Miracle-dz/UniFAR-FTUs huggingface dataset:
Knowledge and Skills for Life: School Libraries in Disadvantaged Areas of Northern Ireland

This study involved data collection and analysis from four distinct phases of research to establish the features of current provision of post-primary school library services in Northern Ireland; and how these services are being implemented in disadvantaged areas. The research also considers the challenges for school library provision, explores examples of good practice, and sets out recommendations for the future for both provision within schools and at a Northern Ireland policy level.
Construction and Validation of Alternative Usability Scale

Usability is the extent of a system being user-friendly. The aim of this research was to make a test to measure usability based on five-factor model of usability by Nielsen (1993). Total of 755 participants (Mage=26.1, SD=5.86) representing the users of 21 types of products or services gave responses. Psychometric analyses were done. The test with fifteen items did not fit the model of its parent theory as revealed by confirmatory factor analysis. Principal component analysis was conducted and some items were deleted. Finally, a test of 12 items with two subscales was made. The participants were given a survey in English but they were not its native speakers. The future research can take native speakers and more diverse products’ or services’ users for psychometric analyses of the 15-item version.
Neue Therapieansätze bei progredienter Multipler Sklerose

Die MS (Multiple Sklerose) ist eine chronisch inflammatorische Erkrankung des ZNS (Zentralnervensystems), die durch Demyelinisierung, einhergehend mit axonaler und neuronaler Degeneration, gekennzeichnet ist. Die meisten Patienten haben initial einen schubförmig-remittierenden Verlauf (RRMS, 85%), der im Mittel nach 15–20 Jahren in einen sekundär chronisch progredienten Verlauf (SPMS) übergeht. Ein kleiner Teil von 10–15% der Patienten hat keine Schübe, sondern eine schleichende Akkumulation von Behinderung, die PPMS (primär progrediente Multiple Sklerose).
Fertility Protection, A Novel Concept: Umbilical Cord Mesenchymal Stem Cell-Derived Exosomes Protect against Chemotherapy-Induced Testicular Cytotoxicity

Currently, there is no viable option for fertility preservation in prepubertal boys. Experimentally, controlled vitrification of testicular tissue has been evaluated and found to cause potential structural damage to the spermatogonial stem cell (SSC) niche during cryopreservation. In this report, we leveraged the regenerative effect of human umbilical cord-derived Mesenchymal stem cell exosomes (h-UCMSC-Exo) to protect against testicular damage from the cytotoxic effects of polychemotherapy (CTX). A chemotherapy-induced testicular dysfunctional model was established by CTX treatment with cyclophosphamide and Busulfan in vitro (human Sertoli cells) and in prepubescent mice. We assessed the effects of the exosomes by analyzing cell proliferation assays, molecular analysis, immunohistochemistry, body weight change, serum hormone levels, and fertility rate. Our data indicates the protective effect of h-UCMSC-Exo by preserving the SSC niche and preventing testicular damage in mice. Interestingly, mice that received multiple injections of h-UCMSC-Exo showed significantly higher fertility rates and serum testosterone levels (p < 0.01). Our study demonstrates that h-UCMSC-Exo can potentially be a novel fertility protection approach in prepubertal boys triaged for chemotherapy treatment.
Dual-Band and Dual-Polarized Shared-Aperture Phased-Array Antennas With Enhanced Beam Coverage for 5G FR2 and 6G FR3

This article proposes an antenna that employs the shared aperture concept and is devised to simultaneously operate in the dual bands of Ku and Ka while supporting dual polarization. The antenna element is specified according to the four distinct derivation processes. The port isolation is enhanced by using an indirect feeding mechanism through slot aperture coupling integrated with substrate integrated waveguide (SIW) feed. Based on the antenna array theory, the extended array structure ensures optimized interantenna spacings. The reflection coefficient of the antenna element satisfies below −10 dB for both operating bands. In addition, interport isolation surpasses 30 dB in Ku-band and 20 dB in Ka-band. For the demonstration of beam-steering capabilities, distinct array structures are devised and constructed for each band. Both simulations and measurements for the Ku-band feature a beam-steering angle exceeding ±40° for both polarizations, with a peak gain of 10.3 dBi based on a <inline-formula> <tex-math notation="LaTeX">$1\times3$ </tex-math></inline-formula> array antenna structure. In the case of the Ka-band, measurements and simulations consistently demonstrate a beam-steering angle of no less than ±43° across both polarizations. This results in a maximum gain of 13.1 dBi based on a <inline-formula> <tex-math notation="LaTeX">$1\times5$ </tex-math></inline-formula> array antenna structure.
Aspects of biological diversity in the CONECOFOR plots. V. Deadwood surveying experiments in alpine and mediterranean forest ecosystems

In recent years, deadwood has become more and more considered as indicator in the assessment of the biodiversity and naturalness of forest ecosystems. Its occurrence, in an appropriate proportion according to forest use, is fundamental for the maintenance of biological diversity, since it represents a microhabitat for hundred of species of invertebrates, fungi, bryophytes, lichens, amphibians, small mammals and birds. Having acknowledged its importance in forest coenoses, quantification of deadwood components in a given habitat, in relation to forest type and type of management, becomes essential. In our study, different survey designs were tested and compared for assessing deadwood components: stumps, lying coarse wood pieces and lying fine wood pieces. As expected, the experiments carried out show that sample-based estimates of ground necromass tend to be more accurate as the quantity of necromass present within the area to be surveyed and the size of the sampling units increase. The adoption of four 7-m-radius subplots in a systematic configuration has proved to be a good compromise between accuracy and survey costs for volume estimation of stumps and lying wood pieces within the examined experimental forest stand plot.
Enhanced Catalytic Soot Oxidation over Co-Based Metal Oxides: Effects of Transition Metal Doping

A series of Co-M (M = Fe, Cr, and Mn) catalysts were synthesized by the sol-gel method for soot oxidation in a loose contact mode. The Co-Fe catalyst exhibited the best catalytic activity among the tested samples, with the characteristic temperatures (T10, T50, and T90) of 470 °C, 557 °C, and 602 °C, respectively, which were 57 °C, 51 °C, and 51 °C lower than those of the CoOx catalyst. Catalyst characterizations of N2 adsorption–desorption, X-ray diffraction (XRD), X-ray photo-electron spectrometry (XPS), and the temperature programmed desorption of O2 (O2-TPD) were performed to gain insights into the relationships between the activity of catalytic soot oxidation and the catalyst properties. The content of Co2+ (68.6%) increased due to the interactions between Co and Fe, while the redox properties and the relative concentration of surface oxygen adsorption (51.7%) were all improved, which could significantly boost the activity of catalytic soot oxidation. The effects of NO and contact mode on soot oxidation were investigated over the Co-Fe catalyst. The addition of 1000 ppm of NO led to significant reductions in T10, T50, and T90 by 92 °C, 106 °C, and 104 °C, respectively, compared to the case without the NO addition. In the tight contact mode, the soot oxidation was accelerated over the Co-Fe catalyst, resulting in 46 °C, 50 °C, and 50 °C reductions in T10, T50, and T90 compared to the loose contact mode. The comparison between real soot and model Printex-U showed that the T50 value of real soot (455 °C) was 102 °C lower than the model Printex-U soot.
Structural Studies of Klebsiella pneumoniae Fosfomycin-Resistance Protein and Its Application for the Development of an Optical Biosensor for Fosfomycin Determination

Fosfomycin-resistance proteins (FosAs) are dimeric metal-dependent glutathione transferases that conjugate the antibiotic fosfomycin (Fos) to the tripeptide glutathione (γ-Glu-Cys-Gly, GSH), rendering it inactive. In the present study, we reported a comparative analysis of the functional features of two FosAs from Pseudomonas aeruginosa (FosAPA) and Klebsiella pneumoniae (FosAKP). The coding sequences of the enzymes were cloned into a T7 expression vector, and soluble active enzymes were expressed in E. coli. FosAKP displayed higher activity and was selected for further studies. The crystal structure of the dimeric FosAKP was determined via X-ray crystallography at 1.48 Å resolution. Fos and tartrate (Tar) were found bound in the active site of the first and second molecules of the dimer, respectively. The binding of Tar to the active site caused slight rearrangements in the structure and dynamics of the enzyme, acting as a weak inhibitor of Fos binding. Differential scanning fluorimetry (DSF) was used to measure the thermal stability of FosAKP under different conditions, allowing for the selection of a suitable buffer to maximize enzyme operational stability. FosAKP displays absolute specificity towards Fos; therefore, this enzyme was exploited for the development of an enzyme-based colorimetric biosensor. FosAKP was tethered at the bottom of a plastic cuvette using glutaraldehyde chemistry to develop a simple colorimetric method for the determination of Fos in drinking water and animal plasma.
The Karlsruhe Institute of Technology Systems for the News Translation Task in WMT 2017

We present our experiments in the scope of the news translation task in WMT 2017, in three directions: German → English, English → German and English → Latvian. The core of our systems is the encoder-decoder based neural machine translation models , enhanced with various modeling features, additional source side augmentation and output rescoring. We also ex-periment various methods in data selection and adaptation.
Menstruation-related symptoms are associated with physical activity and midpoint of sleep: a pilot study

Introduction Menstruation-related symptoms (MRSs) significantly impact women's health and contribute to economic burdens worldwide. Current interventions, primarily pharmacological ones, have limitations and side effects that underscore the need for alternative management strategies. This study explores the association between MRSs and lifestyle factors, specifically physical activity and sleep timing across menstrual cycle phases, to inform non-pharmacological intervention development. Methods Fourteen female students from Ritsumeikan University, Japan, with regular menstrual cycles (25–38 days), not on hormonal treatment or engaged in shift work, participated in this observational study. Using a Fitbit Inspire 2, total daily energy expenditure (TDEE) and sleep timing were monitored over a complete cycle. Menstrual cycle phases were defined based on ovulation day, predicted using home luteinizing hormone tests. Participants completed daily electronic questionnaires rating MRSs using a modified menstrual distress questionnaire. Data were analyzed using a generalized linear mixed model with a gamma distribution and logarithmic link function, examining the relationship of TDEE and the midpoint of sleep time (MS time) with MRS severity. Results and discussion The following observations were noted: first, MRS severity, except for behavioral change symptoms, significantly increased during the menstrual and luteal phases compared to the follicular phase. Second, delayed MS time was associated with reduced pain, concentration symptoms, water retention, and negative affect during the menstrual phase and reduced negative affect during the luteal phase. Finally, an increase in TDEE was associated with reduced concentration symptoms, autonomic reaction symptoms, and negative affect during the menstrual and luteal phases and reduced water retention only during the luteal phase. This study provides insights into the relationship between MRSs and TDEE/MS time, suggesting potential non-therapeutic approaches for symptom management, though further research is needed to substantiate these findings for practical applications.
Attitudes of Kurdish university students towards the English language, English language education policies, and English language learning purposes

Similar to other parts of the world, Kurdish speakers of English have been subject to English fever. They have a strong desire to learn and speak English. An army of teachers is currently teaching Kurdish speakers to learn English. However, few of them acquire the required level of English when they move from high school level to university one. This might partly be associated with their attitudes towards not only the English language but the English language policies and practices that are currently adopted. Attitudes towards the English language have been extensively investigated both quantitatively and qualitatively in diversified educational and cultural contexts. Furthermore, a few studies have been conducted to investigate the attitudes of Kurdish students towards the English language, but their attitudes to English language education policies and English language learning purposes have yet remained unknown. Therefore, this study is anchored on investigating Kurdish undergraduate students’ attitudes towards the English language, English language education policies that are currently applied in Iraqi Kurdistan, and students’ purposes for learning English. It further concentrates on the effect of such variables as gender and year of study on attitudes. For this purpose, the study utilized a questionnaire consisting of 42 items on a 6-point Likert scale surveyed online on a sample of 154 students belonging to different ages, genders, years of study, and majors. The analysis of the data showed that Kurdish university students held neutral to mildly positive attitudes to the English language and English learning purposes. Nevertheless, they held slightly positive attitudes towards English language education policies. The study concludes that, although fundamental transformations have been achieved in the past two decades, the neutral attitudes show that efforts are yet to be made to satisfy students’ needs and desires, particularly with regard to the policies and practices that are currently adopted. This study, different from previous ones, reveals students’ attitudes towards English education policies whose findings are significant for English language education policymakers.
An Optimized Cost Flow Algorithm to Spread Cells in Detailed Placement

Placement is an important and challenging step in VLSI physical design. The placement solution can significantly impact timing and routability. In sub-nanometric technology nodes, several restrictions have been imposed on the placement solutions. These restrictions make designing an optimized and legal solution very hard. Achieving optimized placement solutions is especially challenging in regions with high-density utilization. The quality of placement solution can significantly impact the final circuit implementation. In this work, we present a cell spreading algorithm to move cells out from high-density utilization regions. Our algorithm opens up new spaces in regions with high cell concentration. These spaces can then be exploited by detailed placement algorithms to further optimize the placement solution. The objective of our technique is to reduce area density utilization while considering cell displacement and circuit delay. The outcome of the proposed algorithm is to obtain a uniform distribution of cells in the placement area while having minimal effects on the delay. To achieve this goal, our proposed algorithm uses branch and cut, and network flow techniques. Experimental results on industrial and academic circuits illustrate that our proposed algorithm can minimize circuit delay (up to 25%), cell displacement (up to 17μ m), dynamic power consumption (up to 5.3%), and leakage power (up to 15%).
Moderating Effect of Grip Strength in the Association between Diabetes Mellitus and Depressive Symptomatology

Diabetes mellitus and depression rank among the leading causes of disease burden and are present in the top ten causes of disability-adjusted life years worldwide. Numerous studies have shown that both depression and diabetes have a detrimental effect on the quality of life, and when they coexist, the effect is considerably worse. This study aimed to analyse how grip strength moderates the relationship between diabetes and depressive symptoms among middle-aged and older adults. In total, 41,701 participants (18,003 men) in wave 8 of the cross-sectional population-based Survey of Health, Ageing, and Retirement in Europe (2019/2020) data were studied. A dynamometer was used to test grip strength twice on each hand. Depressive symptoms were measured using the 12-item EURO-D scale. The relationship between diabetes and depressive symptoms is negatively moderated by grip strength (male: B = −0.03, 95% CI = −0.04, −0.03; female: B = −0.06, 95% CI = −0.07, −0.06). Furthermore, the significant zone grip strength moderation values for males and females were less than 48.7 kg and 38.9 kg, respectively. Muscular strength was a moderator of depressive symptoms, attenuating its association with diabetes. This supports the premise that physical activity, namely muscle-strengthening exercises, should be included in diabetes treatment programs.
Assessment of carbon loss related to Soil loss in the tropical watershed of Maharashtra, India

Soil carbon pools have a significant impact on the global carbon cycle and soil erosion caused by natural or human activities is one of the main drivers of changes in soil carbon sequestration. The present study aimed to estimate the carbon loss associated with soil loss in the watershed using remote sensing and GIS techniques. The study was carried out at the Central MPKV Campus Watershed, Rahuri, located in the rain shadow region of the Maharashtra state, India. The soil loss from the watershed was estimated using USLE model. The soil loss and carbon loss from the watershed were estimated before the implementation of conservation measures and after the implementation of conservation measures. It was found that the average annual soil loss from the watershed before and after conservation measures was 18.68 t/ha/yr and 9.41 t/ha/yr, respectively. Carbon loss was determined by soil loss rate, organic carbon content and the carbon enrichment ratio. The carbon loss from the watershed before and after conservation measures was 348.71 kgC/ha/yr and 205.52 kgC/ha/yr. The findings revealed that soil and carbon erosion was very severe on steep slopes without conservation measures and with limited vegetation cover. It was found that by reducing the carbon loss associated with soil loss, soil conservation measures not only aid in the conservation of natural resources but also serve as a climate change mitigation measure.
Profitability Optimization of Dairy Farms: The Effect of Pregnancy Rate and Culling Decision

Simple Summary In dairy farms, the culling decision is a complex decision that is influenced by many factors. Economy must also be taken into account when making a decision. The aim of the study was to use a microsimulation to specifically determine the date of culling in addition to the effect of different levels of pregnancy rate on milk production. The results showed that increasing the pregnancy rate successfully reduced the length of the calving interval, but the improved pregnancy rate did not show a significant increase in milk production. Based on this, dairies can more easily determine the time of culling since it has been shown how the milk production of cows can be expected to develop with different pregnancy rates. Abstract One of the most important decisions in dairy cattle production today is the correct choice of culling time for cows. In the culling decision process, the farmer has to take into account a number of factors, the complexity of which makes the decision-making task difficult. A crucial factor is the evolution of reproductive indicators. The aim of the research was to develop a microsimulation method that can be used to easily investigate the impact on profitability of increasing pregnancy rates and when the culling decision is made. In the microsimulation, the stock was examined without changing any other conditions. A microsimulation method has been developed to determine with high accuracy the effect of the pregnancy rate and the increase in culling days on the economic indicators of individual dairy farms. By microsimulation, the effect of changing these two parameters on the expected milk production of cows, the most important economic indicator for cattle farms, was investigated. The other parameters of economic importance were simulated using a cattle farm database. The purpose of microsimulation is to assist in producing certain managerial decisions in order to achieve better profitability and economic efficiency. In summary, the results showed that increasing the pregnancy rate can successfully reduce the length of the calving interval, but the improved pregnancy rate did not show a significant increase in milk production. In order to obtain results that can be used by farms, the authors intend to further develop the model in the future, adapting it to farms and taking into account their specificities.
Discrete Aurora at Mars: Insights Into the Role of Magnetic Reconnection

Discrete aurora are sporadic emissions of light originating in Mars upper atmosphere. We report nadir imaging observations from MAVEN's Imaging UltraViolet Spectrograph which identify the conditions which trigger electron precipitation causing these events. Prior studies have shown that discrete aurora events in the strong crustal magnetic field region in the southern hemisphere are the brightest and most repeatable compared to events occurring outside the region. Our new data set offers a more complete and accurate characterization of aurora in this area. The region of strongest crustal fields is composed of two distinct magnetic regions, with magnetic fields in opposite directions; discrete aurora events trigger in one region after dusk and in the other before dawn. Magnetic reconnection in these two adjacent regions with the draped interplanetary field may open the crustal fields in these regions during opposing local times. Particle precipitation can then cause discrete aurora at the observed times and locations.