Miracle-dz/UniFAR-FTUs huggingface dataset:
MetNet: Software to Build and Model the Biogenetic Lattice of Arabidopsis

MetNet (http://www.botany.iastate.edu/∼mash/metnetex/metabolicnetex.html) is publicly available software in development for analysis of genome-wide RNA, protein and metabolite profiling data. The software is designed to enable the biologist to visualize, statistically analyse and model a metabolic and regulatory network map of Arabidopsis, combined with gene expression profiling data. It contains a JAVA interface to an interactions database (MetNetDB) containing information on regulatory and metabolic interactions derived from a combination of web databases (TAIR, KEGG, BRENDA) and input from biologists in their area of expertise. FCModeler captures input from MetNetDB in a graphical form. Sub-networks can be identified and interpreted using simple fuzzy cognitive maps. FCModeler is intended to develop and evaluate hypotheses, and provide a modelling framework for assessing the large amounts of data captured by high-throughput gene expression experiments. FCModeler and MetNetDB are currently being extended to three-dimensional virtual reality display. The MetNet map, together with gene expression data, can be viewed using multivariate graphics tools in GGobi linked with the data analytic tools in R. Users can highlight different parts of the metabolic network and see the relevant expression data highlighted in other data plots. Multi-dimensional expression data can be rotated through different dimensions. Statistical analysis can be computed alongside the visual. MetNet is designed to provide a framework for the formulation of testable hypotheses regarding the function of specific genes, and in the long term provide the basis for identification of metabolic and regulatory networks that control plant composition and development.
Implementação de um geocatálogo utilizando banco de dados orientado a grafos para apoio à metodologia SERVUS

This research presents the construction of a Geo-Catalogue using semantics and ontologies to aid in the discovery process of geographic features in service of a spatial data infrastructure. Its architecture incorporates a non-relational graph database and is liable for deployment to an environment of clouds. For its validation, the methodology of development of system called SERVUS was used. It is a methodology specialized in services of geospatial oriented architecture. The study of the case discusses a typical situation of government auditing in the environmental theme.
Teaching C in a Functional Style

The rst introduction to imperative programming for the majority of our students is with C, but fortunately it is preceded by a course on problem solving and program design using the lazy functional language Miranda. C is a diicult language to learn, but by drawing on the skills taught in the Miranda course, notions such as modularity, information hiding, recursion, abstraction, top-down design, functional composition, composite types, and higher order functions can be introduced relatively painlessly. One of the major tasks for programmers is the design and implementation of Abstract Data Types (ADTs). This is made more diicult in C by being based on dynamic data structures coded with pointers. We describe a translation strategy from a Miranda version of an ADT to a C version, which utilises all of the good programming habits developed with Miranda. The translation from Miranda to C allows a wide ranging discussion of many important topics: strict versus non-strict functions, recursive data structures, polymorphism, the importance of typing, pattern matching versus information hiding in ADTs, destructive versus non-destructive assignment, and the trade-oos between understandability and eeciency. This approach to C programming was used in a course at the end of 1993, and the results of a student questionnaire are brieey reported.
Precession and recession of the rock'n'roller

We study the dynamics of a spherical rigid body that rocks and rolls on a plane under the effect of gravity. The distribution of mass is non-uniform and the centre of mass does not coincide with the geometric centre. The symmetric case, with moments of inertia I1 = I2 < I3, is integrable and the motion is completely regular. Three known conservation laws are the total energy E, Jellett's quantity QJ and Routh's quantity QR. When the inertial symmetry I1 = I2 is broken, even slightly, the character of the solutions is profoundly changed and new types of motion become possible. We derive the equations governing the general motion and present analytical and numerical evidence of the recession, or reversal of precession, that has been observed in physical experiments. We present an analysis of recession in terms of critical lines dividing the (QR, QJ) plane into four dynamically disjoint zones. We prove that recession implies the lack of conservation of Jellett's and Routh's quantities, by identifying individual reversals as crossings of the orbit (QR(t), QJ(t)) through the critical lines. Consequently, a method is found to produce a large number of initial conditions so that the system will exhibit recession.
Sensorimotor Information flow in Genetic Regulatory Network driven control systems

We present results from applying information theory based measures to simulated robots controlled by evolved Genetic Regulatory Networks. Measuring the information flow across sensory and effector surfaces, we create an information profile illustrated using area-proportional Venn diagrams. We examine the relationship between this information profile and various elements of the overall system including the GRN controlling the robot, the environment, the nature of the task for which the GRN controller has been evolved, and evolutionary fitness.
Application of Probabilistic Multiple-Bias Analyses to a Cohort- and a Case-Control Study on the Association between Pandemrix™and Narcolepsy

Background An increase in narcolepsy cases was observed in Finland and Sweden towards the end of the 2009 H1N1 influenza pandemic. Preliminary observational studies suggested a temporal link with the pandemic influenza vaccine Pandemrix™, leading to a number of additional studies across Europe. Given the public health urgency, these studies used readily available retrospective data from various sources. The potential for bias in such settings was generally acknowledged. Although generally advocated by key opinion leaders and international health authorities, no systematic quantitative assessment of the potential joint impact of biases was undertaken in any of these studies. Methods We applied bias-level multiple-bias analyses to two of the published narcolepsy studies: a pediatric cohort study from Finland and a case-control study from France. In particular, we developed Monte Carlo simulation models to evaluate a potential cascade of biases, including confounding by age, by indication and by natural H1N1 infection, selection bias, disease- and exposure misclassification. All bias parameters were evidence-based to the extent possible. Results Given the assumptions used for confounding, selection bias and misclassification, the Finnish rate ratio of 13.78 (95% CI: 5.72–28.11) reduced to a median value of 6.06 (2.5th- 97.5th percentile: 2.49–15.1) and the French odds ratio of 5.43 (95% CI: 2.6–10.08) to 1.85 (2.5th—97.5th percentile: 0.85–4.08). Conclusion We illustrate multiple-bias analyses using two studies on the Pandemrix™-narcolepsy association and advocate their use to better understand the robustness of study findings. Based on our multiple-bias models, the observed Pandemrix™-narcolepsy association consistently persists in the Finnish study. For the French study, the results of our multiple-bias models were inconclusive.
Frameworks of Composite Services Execution Engine with Feedback Control

According to the SOA, we proposed the framework of composite service execution engine WebJetFlow. In this framework, to guarantee the response time from different services of different levels, we designed and implemented the flow execution structure with dual feedback control loops, which are in the process executor and service proxy respectively. Moreover, we separated process executor and service proxy to decouple process execution and service invocation. The new idea of this paper is that decoupling method improves the efficiency and throughput of the engine, and introduces the feedback control mechanism that enables the engine to provide response time guarantees for different services even when load varies significantly.
Proof of the Conjecture that the Planar Self-Avoiding Walk has Root Mean Square Displacement Exponent 3/4

This paper proves the long-standing open conjecture rooted in chemical physics (Flory (1949)) that the self-avoiding walk (SAW) in the square lattice has root mean square displacement exponent \nu= 3/4. This value is an instance of the formula \nu=1 on Z and \nu = max(1/2, 1/4 + 1/d) in Z^d for dimensions d \geq 2, which will be proved in a subsequent paper. This expression differs from the one that Flory's arguments suggested. We consider (a) the point process of self-intersections defined via certain paths of the symmetric simple random walk in Z^2 and (b) a ``weakly self-avoiding cone process'' relative to this point process when in a certain "shape". We derive results on the asymptotic expected distance of the weakly SAW with parameter \beta>0 from its starting point, from which a number of distance exponents are immediately collectable for the SAW as well. Our method employs the Palm distribution of the point process of self-intersection points in a cone.
The impact of endorsements in intra-party elections: Evidence from open primaries in a new Portuguese party

What affects the prospects of candidates in open intra-party elections? This research article examines the determinants of candidate performance in the first open party primaries conducted by LIVRE, a newly emerged Portuguese party, in 2015. This innovative process of candidate selection allowed individuals from outside the party not only to vote but also to run for office. Through the construction of an original dataset and the use of social network analysis, this study shows that centrality in the network of endorsements has a significant impact on the probability to be selected in party lists. Our findings shed additional light on the determinants of success in candidate selection and open new insights into the dynamics behind party primaries.
Temporal constraints on experimental emmetropization in infant monkeys.

PURPOSE To characterize the temporal integration properties of the emmetropization process, the authors investigated the effects of brief daily interruptions of lens wear on the ocular compensation for negative lenses in infant rhesus monkeys. METHODS Eighteen monkeys wore -3 D lenses binocularly starting from approximately 3 weeks of age. Six of these monkeys wore the lenses continuously. For the other animals, the -3 D lenses were removed for four 15-minute periods each day. During these periods, the monkeys viewed through either zero-power lenses (n = 6) or +4.5 D lenses (n = 6). Three monkeys reared with binocular plano lenses and 16 monkeys reared normally served as controls. Refractive development was assessed by cycloplegic retinoscopy and A-scan ultrasonography. RESULTS As expected, the group of animals that wore the -3 D lenses continuously exhibited clear evidence of compensating axial myopia. These predictable myopic changes were mostly eliminated by the brief, daily periods of viewing through plano lenses. Interestingly, brief periods of viewing through +4.5 D lenses produced weaker protective effects. CONCLUSIONS Brief periods of unrestricted vision can prevent the axial myopia normally produced by long daily periods of imposed hyperopic defocus. Thus, the temporal integration properties of the emmetropization process normally reduce the likelihood that transient periods of hyperopic defocus will cause myopia.
Improving TCP performance over wireless networks

This paper proposes a novel end-to-end congestion control mechanism called TCP NewZag. NewZag is simple and effective in dealing with random packet loss, so it can improve TCP performance in the wireless network. TCP NewZag proposes two new mechanisms: (1) a new end-to-end loss differentiation algorithm (LDA); (2) the adjustments of TCP NewReno multiplicative decrease algorithm. These two mechanisms only require the adjustment of TCP sender side, while the receiver side protocol remains the same. Based on experimental measurements of single link, it is shown that NewZag achieves significant throughput improvement when the wireless random packet losses occur. Compared with NewReno in 0.5% random packet loss rate, 20% throughput improvement can be demonstrated.
The Synthesis and Characterization of Hydroxyapatite-β-Alanine Modified by Grafting Polymerization of γ-Benzyl-l-glutamate-N-carboxyanhydride

In this study, hydroxyapatite (HAP) was surface-modified by the addition of β-alanine (β-Ala), and the ring-opening polymerization of γ-benzyl-l-glutamate-N-carboxy-anhydride (BLG-NCA) was subsequently initiated. HAP containing surface poly-γ-benzyl-l-glutamates (PBLG) was successfully prepared in this way. With the increase of PBLG content in HAP-PBLG, the solubility of HAP-PBLG increased gradually and it was ultimately soluble in chloroform. HAP-PLGA with surface carboxyl groups was obtained by the catalytic hydrogenation of HAP-PBLG. In the process of HAP modification, the morphology changes from rod to sheet and from flake to needle. The effect of BLG-NCA concentration on the character of hydroxyapatite-β-alanine-poly(γ-benzyl-l-glutamate) (HAP-PBLG) was investigated. The existence of amino acids on the HAP surfaces was confirmed in the resulting Fourier transform infrared (FTIR) spectra. The resulting powder X-ray diffraction patterns indicated that the crystallinity of HAP decreased when the ratio of BLG-NCA/HAP-NH2 increased to 20/1. Transmission electron microscopy (TEM) indicated that the particle size of HAP-PBLG decreased significantly and that the resulting particles appeared less agglomerated relative to that of the HAP-NH2 crystals. Furthermore, 1H-NMR spectra and FTIR spectra revealed that hydroxyapatite-β-alanine-poly (l-glutamic acid) (HAP-PLGA) was able to successfully bear carboxylic acid groups on its side chains.
HS-ROBDD: an efficient variable order binary decision diagram

Reduced Ordered Binary Decision Diagrams (ROBDDs) are frequently used as the representation of choice to solve various CAD problems such as synthesis, digital-system verification and testing. The size of an ROBDD for a function can be increased exponentially by the number of independent variables of the function that is called "memory explosion problem". Since the size of an ROBDD heavily depends on the variable order used, there is a strong need to find variable orders that minimize the number of nodes in an ROBDD. As finding the optimal variable ordering is an NP-Complete problem, in this paper, we use Harmony Search (HS) to find an optimal variable ordering in binary decision diagram. Some benchmarks form LGSynth91 are used to evaluate our suggestion method. Obtained results show that this method has the ability to find optimal order of input variable and reduce the size of ROBDD considerably.
Ju n 19 99 Apparent multifractality in financial time series

We present a exactly soluble model for financial time series that mimics the long range volatility correlations known to be present in financial data. Although our model is ‘monofractal’ by construction, it shows apparent multiscaling as a result of a slow crossover phenomenon on finite time scales. Our results suggest that it might be hard to distinguish apparent and true multifractal behavior in financial data. Our model also leads to a new family of stable laws for sums of correlated random variables. Many time series exhibit interesting scaling properties. This means that if x(t) denotes the time series, the probability distribution of the variations δT x = x(t + T ) − x(t), rescaled by a lag-dependent factor ξ(T ), can be written as: P (δT x, T ) = 1 ξ(T ) F (
Kafka, Samza and the Unix Philosophy of Distributed Data

Apache Kafka is a scalable message broker, and Apache Samza is a stream processing framework built upon Kafka. They are widely used as infrastructure for implementing personalized online services and real-time predictive analytics. Besides providing high throughput and low latency, Kafka and Samza are designed with operational robustness and long-term maintenance of applications in mind. In this paper we explain the reasoning behind the design of Kafka and Samza, which allow complex applications to be built by composing a small number of simple primitives – replicated logs and stream operators. We draw parallels between the design of Kafka and Samza, batch processing pipelines, database architecture, and the design philosophy of Unix.
Role of Diet, Nutrients, Spices and Natural Products in Diabetes Mellitus

Diabetes mellitus is a global disease, prevails all over the world, though the prevalence rate differs from country to country. Diabetes, a disorder of carbohydrate metabolism, is characterized by high blood glucose level and glycosuria resulting from dysfunction of pancreatic beta cells and insulin resistance. In advance stages of diabetes, metabolism of protein and lipid is also altered. Many factors like heredity, age, obesity, diet, sex, sedentary life style, socio economic status, hypertension and various stresses are involved in the etiology of diabetes mellitus. Drug, diet and recently spices therapies are the major approaches used for treatment and control of diabetes mellitus. In drug therapy, hypoglycemic medicines and insulin are used. In diet therapy, diet composition, amount, distribution and time of food intake are important factors. The diet must be acceptable, must supply adequate amount of nutrients, and be formulated in a way to normalize body weight. The diet for diabetic children should have sufficient calories for adequate nutrition, normal weight gain and growth. The diet should be high in complex carbohydrate, low in simple carbohydrate, low in fat and high in mono-unsaturated fatty acid. High fiber diets are beneficial for treatment of diabetes. Soluble fibers are more effective than insoluble fibers. Chromium is important for diabetes and functions in carbohydrate and lipid metabolism primarily via its role in potentiating insulin action in carbohydrate metabolism. In the spices therapy, cinnamon, cloves, bay leaves and turmeric have an insulin potentiating activity and are beneficial for diabetic individuals. Cinnamon is effective in reducing glucose level in type 2 diabetic individuals. The effective ingredient in cinnamon for hypoglycemic function has been identified as methyl hydroxy chalcone polymers. Other plant products have also hypoglycemic activities and may have beneficial role in treatment of diabetes mellitus. Cinnamon should be a part of diabetic diets for its hypoglycemic effect in diabetic individuals.
The Associations Between the Maladaptive Personality Dimensions of Neediness and Self-Criticism, Defense Styles, Selfobject Needs, and Attachment Styles in an Iranian Sample

The present study extends previous findings by examining whether defense styles, selfobject needs, attachment styles relate to Neediness and Self-Criticism, as maladaptive personality dimensions focused, respectively, on relatedness and self-definition in an Iranian sample. Three hundred and 52 participants completed a sociodemographic questionnaire as well as the Persian forms of the Depressive Experiences Questionnaire, Experience of Close Relationships-Revised, Defense Style Questionnaire, Beck Depression Inventory—II and Selfobject Needs Inventory. Two multiple linear regression analyses, entering Self-criticism and Neediness as criterion variables, were computed. According to the results, high attachment anxiety, high immature defenses, high depressive symptoms, and high need for idealization were related to self-criticism, and explained 47% of its variance. In addition, high attachment anxiety, low mature defenses, high neurotic defenses, high avoidance of mirroring, and low avoidance of idealization/twinship were related to neediness, and explained 40% of its variance. A principal components analysis was performed, entering all the studied variables. Three factors emerged; 1 describing a maladaptive form of psychological functioning and 2 describing more mature modes of psychological functioning. The results are discussed in their implications for the understanding of neediness and self-criticism as maladaptive personality dimensions focused, respectively, on relatedness and self-definition.
Learning styles in relation to information processing modes and multiple talents

The present study was undertaken to investigate the learning style patterns, information processing modes and multitalent characteristics of university students, and also to determine the effect of gender as well as the influence of concerned disciplines on the above mentioned variables. The sample comprised of four hundred and thirty four Delhi University students. The independent variables involved were gender (male Vs. female) and five disciplines of study (Arts, Science, Commerce, Fine Arts and Management Students). First, on the basis of Kolb's (1985) LSI, the specific learning styles of the subjects'were assessed. The subject's were then administered, the SOLAT-C Form by Torrance and Reynolds (1980), with the help of which the subjects, information processing modes could be determined. Lastly, the MPI by Khatena and Morse (1986); was administered. Such an instrument served as a viable screening device for the identification of the students' multiple talents (as measured from their versatility , as an index of multi talent perception). Statistical analysis of the results reveal that (a) University students differed in their learning style patterns and modes of information processing ways in terms of their gender as well as the type of concerned disciplines to which they belonged. (b) University students displayed multitalent characteristics (as indicated from their, Versatility as an index of multi talent perception. Gender, however has no influence on this variable, but the type of faculty to which they belong seems to have an effect on the versatility dimension of the students.
Continuity and discontinuity in education: example of transition from preschool to school

ABSTRACT This article reconsiders multiple perspectives about continuity and discontinuity of early childhood education. Theoretical starting points, childhood policies and research of continuity and discontinuity exemplified through transition to school, are promising in rethinking and creating productive practices of childhood in different sociocultural contexts of childhood from the perspective of children and adults. The focus is on the compromise-approach in interpreting children’s agency, their experiences, continuity and discontinuity in the context of transition and in researching transition from the children’s perspective. The presupposed reliability and value of children’s views have been empirically examined through research on children’s perspectives about preschool and school. The theoretical frame of the research is sociocultural theory of development, viewing childhood as a sociocultural construction and children as capable and active beings and becomings. Research results confirmed children’s agency, evident in their awareness of social alignment with adult (parents, preschool teachers and teachers) expectations and practices. Insight into children’s views of preschool and school is one way of understanding the reality of childhood and life transitions as a precondition of creating an environment in which children and adults, through reciprocal interactions, achieve mutual accommodations in a continuous process of being and becoming.