Miracle-dz/UniFAR-FTUs huggingface dataset:
Intrinsic foot muscles have the capacity to control deformation of the longitudinal arch

The human foot is characterized by a pronounced longitudinal arch (LA) that compresses and recoils in response to external load during locomotion, allowing for storage and return of elastic energy within the passive structures of the arch and contributing to metabolic energy savings. Here, we examine the potential for active muscular contribution to the biomechanics of arch deformation and recoil. We test the hypotheses that activation of the three largest plantar intrinsic foot muscles, abductor hallucis, flexor digitorum and quadratus plantae is associated with muscle stretch in response to external load on the foot and that activation of these muscles (via electrical stimulation) will generate sufficient force to counter the deformation of LA caused by the external load. We found that recruitment of the intrinsic foot muscles increased with increasing load, beyond specific load thresholds. Interestingly, LA deformation and muscle stretch plateaued towards the maximum load of 150% body weight, when muscle activity was greatest. Electrical stimulation of the plantar intrinsic muscles countered the deformation that occurred owing to the application of external load by reducing the length and increasing the height of the LA. These findings demonstrate that these muscles have the capacity to control foot posture and LA stiffness and may provide a buttressing effect during foot loading. This active arch stiffening mechanism may have important implications for how forces are transmitted during locomotion and postural activities as well as consequences for metabolic energy saving.
Toward Optimal Multiuser Antenna Beamforming for Hierarchical Cognitive Radio Systems

In this paper, we present a joint antenna beamforming and power allocation technique to maximize the multiuser sum rate in an underlying microcellular system which reuses the same spectrum of a macrocellular system. One challenge in this kind of hierarchical cognitive radio (HCR) systems is to manage the interference between the macrocell and the microcell. The key contribution of this paper is to develop an optimization technique for antenna beamforming that can maximize the achievable sum rate of the underlying cognitive radio (CR) microcellular system and control the interference between the macrocell and the microcell with a satisfaction level. The proposed technique optimizes the sum rate performance by maximizing its lower bound and transfers the original non-convex problem into a convex optimization problem by introducing auxiliary variables to confine the intra-user interference power among the secondary system. Next, an iterative sum rate maximization (ISM) algorithm is developed to find the beamforming weights and the allocated power for each secondary user to simultaneously maximize system sum rate, coverage, and concurrent multiuser transmission probability in the HCR system. The developed joint design methodology provides valuable insights into the design of an optimal HCR system for various numbers of users as well as cell coverage, and can quantitatively optimize the performance tradeoffs in the hierarchical multiuser CR systems for current and future wireless communication applications.
Intellectual disability and homelessness.

BACKGROUND The association between poverty and intellectual disability (ID) has been well documented. However, little is known about persons with ID who face circumstances of extreme poverty, such as homelessness. This paper describes the situation of persons with ID who were or are homeless in Montreal and are currently receiving services from a team dedicated to homeless persons. AIMS (1) To describe the characteristics, history and current situation of these persons; and (2) to report within-group differences as a function of gender and current residential status. METHODS The data were collected from files using an anonymous chart summary. Descriptive statistics on the whole sample (n = 68) and inferential statistics on cross-tabulations by gender and residential status were performed. RESULTS Persons with ID exhibited several related problems. Some of these persons, primarily women, experienced relatively short periods of homelessness and their situations stabilised once they were identified and followed up. Other persons with ID experienced chronic homelessness that appeared to parallel the number and severity of their other problems. When compared with a previous epidemiological study of the homeless in Montreal, the population of homeless persons with ID differed from the overall homeless population in a number of respects. CONCLUSION The results suggest prevention and intervention targets. The need for epidemiological research appears particularly clear in light of the fact that below-average intellectual functioning has been identified as a risk factor for homelessness and a predisposing factor for vulnerability among street people.
Leakage Optimized DECAP Design for FPGAs

On-chip decoupling capacitors (Decaps) are widely used to mitigate on-chip power supply noise. At and below 100nm on-chip decaps face leakage and area overhead problems associated with it and is estimated to increase with technology scaling. A recent work has proposed a gated decap structure to reduce leakage in decaps. Their work analyzes leakage saving obtained by implementing gated decap structure in a pipelined super scalar core. FPGAs on the otherhand face similar leakage problem associated with decaps in their unmapped regions. We analyze here the leakage saving due to gated decap structure in FPGAs. With the on-chip gated decap structure we do uniform placement of decaps that achieves decap leakage savings of 7-60% with 39% on an average for various MCNC benchmarks mapped on to the FPGA device
Change in peripheral blood leukocyte telomere length and mortality in breast cancer survivors.

BACKGROUND Progressive telomere shortening with cell division is a hallmark of aging. Short telomeres are associated with increased cancer risk, but there are conflicting reports about telomere length and mortality in breast cancer survivors. METHODS We measured peripheral blood leukocyte telomere length at two time points in women enrolled in a multiethnic, prospective cohort of stage I to stage IIIA breast cancer survivors diagnosed between 1995 and 1999 with a median follow-up of 11.2 years. We evaluated associations between telomere length measured at mean 6 (baseline; LTL0; n = 611) and 30 months (LTL30; n = 478) after diagnosis and the change between those time points (n = 478), with breast cancer-specific and all-cause mortality using Cox proportional hazards models adjusted for possible confounders. Statistical tests were two-sided. RESULTS There were 135 deaths, of which 74 were due to breast cancer. Neither baseline nor 30-month telomere length was associated with either all-cause or breast cancer-specific mortality (LTL0: hazard ratio [HR] = 0.83, 95% confidence interval [CI] = 0.67 to 1.02; HR = 0.88; 95% CI = 0.67 to 1.15; LTL30: HR = 0.78, 95% CI = 0.59 to 1.05; HR = 0.86; 95% = CI = 0.58 to 1.26, respectively). However, participants whose telomeres shortened between baseline and 30 months were at a statistically significantly increased risk of breast cancer-specific (HR = 3.03; 95% CI = 1.11 to 8.18) and all-cause mortality (HR = 2.38; 95% CI = 1.28 to 4.39) compared with participants whose telomeres lengthened. When follow-up was censored at 5-years after diagnosis, LTL0 (HR = 0.66; 95% CI = 0.45 to 0.96), LTL30 (HR = 0.51; 95% CI = 0.29 to 0.92), and change in telomere length (HR = 3.45; 95% CI = 1.11 to 10.75) were statistically significantly associated with all-cause mortality. CONCLUSIONS Telomere shortening was associated with increased risk of breast cancer-specific and all-cause mortality, suggesting that change in blood telomere length over time could be a biomarker of prognosis. Research on determinants of telomere length and change is needed.
The relationship between five-factor model and diagnostic and statistical manual of mental disorder-fifth edition personality traits on patients with antisocial personality disorder

Background: Despite the fact that new criteria of antisocial personality disorder (ASPD) in diagnostic and statistical manual of mental disorders-fifth edition (DSM-5) were resulted from five-factor model (FFM), there is a small amount of studies that investigate the relations between proposed personality traits and FFM. Also, cross-cultural study in this field continuously would be needed. The aim of the present study was to evaluate the relation between the FFM and DSM-5 ASPD pathological traits. Materials and Methods: This study was a cross-sectional study design. The participants consisted of 122 individuals with ASPD that selected from prisoners (73.0%), outpatients (18.0%), and inpatients (9.0%). They were recruited from Tehran Prisoners, and Clinical Psychology and Psychiatry Clinics of Razi and Taleghani Hospitals, Tehran, Iran, since 2013-2014. The Sample was selected based on judgmental sampling. The structured clinical interview for DSM-IV axis II disorders-Personality Questionnaire, NEO-Personality Inventory-Revised, and DSM-5 personality trait rating form were used to diagnosis and assessment of personality disorder. Pearson correlation has been used for data analysis. All statistical analyses were performed using the SPSS 16 software. Results: The results indicate that neuroticism (N) has positive significant relationship with hostility (r = 0.33, P < 0.01), manipulativeness (r = 0.25, P < 0.01), deceitfulness (r =.23, P < 0.01), impulsivity (r = 0.20, P < 0.05), and negative relation with risk taking (r = −0.23, P < 0.01). Also, there was significant relationship between extraversion (E) with manipulativeness (r = 0.28, P < 0.01) and deceitfulness (r = 0.32, P < 0.01). Agreeableness and conscientiousness have negative significant relation with DSM-5 traits. In addition, results showed that there is positive significant relationship between FFM and DSM-5 personality traits with DSM-fourth edition-text revision (DSM-IV-TR) ASPD symptoms (P < 0.01). Conclusion: Except manipulativeness, deceitfulness, and callousness, there is positively significant relationship between DSM-5 ASPD traits and DSM-IV-TR ASPD symptoms. The present study helps to understand the adequacy of dimensional approach to evaluation of ASPD pathology, specifically on Iranian sample.
Hand-arm vibration and the risk of vascular and neurological diseases—A systematic review and meta-analysis

Background Increased occurrence of Raynaud’s phenomenon, neurosensory injury and carpal tunnel syndrome has been reported for more than 100 years in association with work with vibrating machines. The current risk prediction modelling (ISO-5349) for “Raynaud’s phenomenon” is based on a few studies published 70 to 40 years ago. There are no corresponding risk prediction models for neurosensory injury or carpal tunnel syndrome, nor any systematic reviews comprising a statistical synthesis (meta-analysis) of the evidence. Objectives Our aim was to provide a systematic review of the literature on the association between Raynaud’s phenomenon, neurosensory injuries and carpal tunnel syndrome and hand-arm vibration (HAV) exposure. Moreover the aim was to estimate the magnitude of such an association using meta-analysis. Methods This systematic review covers the scientific literature up to January 2016. The databases used for the literature search were PubMed and Science Direct. We found a total of 4,335 abstracts, which were read and whose validity was assessed according to pre-established criteria. 294 articles were examined in their entirety to determine whether each article met the inclusion criteria. The possible risk of bias was assessed for each article. 52 articles finally met the pre-established criteria for inclusion in the systematic review. Results The results show that workers who are exposed to HAV have an increased risk of vascular and neurological diseases compared to non-vibration exposed groups. The crude estimate of the risk increase is approximately 4–5 fold. The estimated effect size (odds ratio) is 6.9 for the studies of Raynaud’s phenomenon when including only the studies judged to have a low risk of bias. The corresponding risk of neurosensory injury is 7.4 and the equivalent of carpal tunnel syndrome is 2.9. Conclusion At equal exposures, neurosensory injury occurs with a 3-time factor shorter latency than Raynaud’s phenomenon. Which is why preventive measures should address this vibration health hazard with greater attention.
A lithotrophic microbial fuel cell operated with pseudomonads-dominated iron-oxidizing bacteria enriched at the anode

In this study, we attempted to enrich neutrophilic iron bacteria in a microbial fuel cell (MFC)‐type reactor in order to develop a lithotrophic MFC system that can utilize ferrous iron as an inorganic electron donor and operate at neutral pHs. Electrical currents were steadily generated at an average level of 0.6 mA (or 0.024 mA cm–2 of membrane area) in reactors initially inoculated with microbial sources and operated with 20 mM Fe2+ as the sole electron donor and 10 ohm external resistance; whereas in an uninoculated reactor (the control), the average current level only reached 0.2 mA (or 0.008 mA cm–2 of membrane area). In an inoculated MFC, the generation of electrical currents was correlated with increases in cell density of bacteria in the anode suspension and coupled with the oxidation of ferrous iron. Cultivation‐based and denaturing gradient gel electrophoresis analyses both show the dominance of some Pseudomonas species in the anode communities of the MFCs. Fluorescent in‐situ hybridization results revealed significant increases of neutrophilic iron‐oxidizing bacteria in the anode community of an inoculated MFC. The results, altogether, prove the successful development of a lithotrophic MFC system with iron bacteria enriched at its anode and suggest a chemolithotrophic anode reaction involving some Pseudomonas species as key players in such a system. The system potentially offers unique applications, such as accelerated bioremediation or on‐site biodetection of iron and/or manganese in water samples.
Un índice de sesgo entre observadores basado en modelos mixtura

Los modelos mixtura son procedimientos apropiados para la valoracion del acuerdo entre dos (o mas) observadores que asumen que los objetos a clasificar se extraen de una poblacion que constituye una mezcla de dos subpoblaciones finitas, la primera de las cuales representa acuerdo sistematico y la segunda acuerdo aleatorio y desacuerdo. Una generalizacion del modelo mixtura basico a cuatro subpoblaciones que representan dos variables latentes con dos clases cada una permite preservar su naturaleza (el ajuste del modelo y la subpoblacion de acuerdo sistematico son iguales) y distinguir ademas una subpoblacion para el acuerdo aleatorio y dos subpoblaciones para el desacuerdo (una para el triangulo superior y otra para el triangulo inferior de la tabla de contingencia). En este contexto es posible definir una medida de sesgo entre observadores basada en modelos mixtura similar al indice descriptivo propuesto por Ludbrook. A mixture model-based rater bias index. Mixture models are outstanding procedures to evaluate rater agreement that assume that the objects to be classified by two observers are extracted from a population that is a mixture of two finite subpopulations, the first one representing systematic agreement and the second one random agreement and disagreement. A generalization of the basic mixture model to include four subpopulations representing two latent variables with two classes allows us to preserve its nature (the fit of the model and the systematic subpopulation are the same) and to distinguish a subpopulation for random agreement and two subpopulations for disagreement (one for the upper triangle and the other for the lower triangle of contingency table). In this context, it is possible to define a new rater bias measure based on a mixture model, which is similar to the descriptive index proposed by Ludbrook.
The Use of Fermented Soybean Meals during Early Phase Affects Subsequent Growth and Physiological Response in Broiler Chicks

The objectives of this experiment was to evaluate the subsequent growth and organ weights, blood profiles and cecal microbiota of broiler chicks fed pre-starter diets containing fermented soybean meal products during early phase. A total of nine hundred 1-d-old chicks were randomly assigned into six groups with six replicates of 25 chicks each. The chicks were fed control pre-starter diet with dehulled soybean meal (SBM) or one of five experimental diets containing fermented SBM products (Bacillus fermented SBM [BF-SBM], yeast by product and Bacillus fermented SBM [YBF-SBM]; Lactobacillus fermented SBM 1 [LF-SBM 1]; Lactobacillus fermented SBM 2 [LF-SBM 2]) or soy protein concentrate (SPC) for 7 d after hatching, followed by 4 wk feeding of commercial diets without fermented SBMs or SPC. The fermented SBMs and SPC were substituted at the expense of dehulled SBM at 3% level on fresh weight basis. The body weight (BW) during the starter period was not affected by dietary treatments, but BW at 14 d onwards was significantly higher (p<0.05) in chicks that had been fed BF-SBM and YBF-SBM during the early phase compared with the control group. The feed intake during grower and finisher phases was not affected (p>0.05) by dietary treatments. During total rearing period, the daily weight gains in six groups were 52.0 (control), 57.7 (BF-SBM), 58.5 (YBF-SBM), 52.0 (LF-SBM 1), 56.7 (LF-SBM 2), and 53.3 g/d (SPC), respectively. The daily weight gain in chicks fed diet containing BF-SBM, YBF-SBM, and LF-SBM 2 were significantly higher values (p<0.001) than that of the control group. Chicks fed BF-SBM, YBF-SBM, and LF-SBM 2 had significantly lower (p<0.01) feed conversion ratio compared with the control group. There were no significant differences in the relative weight of various organs and blood profiles among groups. Cecal microbiota was altered by dietary treatments. At 35 d, chicks fed on the pre-starter diets containing BF-SBM and YBF-SBM had significantly increased (p<0.001) lactic acid bacteria, but lowered Coli-form bacteria in cecal contents compared with those fed the control diet. The number of Bacillus spp. was higher (p<0.001) in all groups except for LF-SBM 1 compared with control diet-fed chicks. At 7 d, jejunal villi were significantly lengthened (p<0.001) in chicks fed the fermented SBMs vs control diet. Collectively, the results indicate that feeding of fermented SBMs during early phase are beneficial to the subsequent growth performance in broiler chicks. BF-SBM and YBF-SBM showed superior overall growth performance as compared with unfermented SBM and SPC.
On Using GIS to Teach in the Social Sciences

FALL 2012 46 courses who have aspirations in business or other fields. Our content is foundational, but not core to their degree programs. Alternatively, our economics, history, and humanities courses also attract undeclared underclassmen because they fulfill certain requirements. But without long-term interest in these fields, students will often disconnect and become frustrated with our content. They sometimes lament our subject matter does not equip them with marketable skills. After all, it is easier for students to associate the practice of chemistry in the “real world” with the study of chemistry in college than, say, to associate the practice of law in the real world with the study of economics or history or English. So, how can a professor of “the dismal science”—or any other social science—engage a group of skeptical students who may be just passing In higher education, teaching is required but learning is optional. For those with a true passion for learning, it is almost unbearable when students do not seem to “get it. ” Yet, as the rising tide of outcomes assessment rolls in, learning communities must come to grips with the fruit of their labor. If we are honest, sometimes the harvest is plentiful, sometimes the pickings are slim, and sometimes we sow apple seeds and get squash! While this experience is not limited to any one discipline, in liberal arts programs the fruit basket can be quite the cornucopia. Why? Increasingly we draw students to our lower-level On Using GIS to Teach in the Social Sciences
An Angiotensin Receptor Blocker Prevents Arrhythmogenic Left Atrial Remodeling in a Rat Post Myocardial Infarction Induced Heart Failure Model

This study investigated the role of angiotensin II receptor blocker in atrial remodeling in rats with atrial fibrillation (AF) induced by a myocardial infarction (MI). MIs were induced by a ligation of the left anterior descending coronary artery. Two days after, the rats in the losartan group were given losartan (10 mg/kg/day for 10 weeks). Ten weeks later, echocardiography and AF induction studies were conducted. Ejection fraction was significantly lower in the MI rats. Fibrosis analysis revealed much increased left atrial fibrosis in the MI group than sham (2.22 ± 0.66% vs 0.25 ± 0.08%, P = 0.001) and suppression in the losartan group (0.90 ± 0.27%, P 0.001) compared with the MI group. AF inducibility was higher in the MI group than sham (39.4 ± 43.0% vs 2.0 ± 6.3%, P = 0.005) and significantly lower in losartan group (12.0 ± 31.6%, P = 0.029) compared with the MI. The left atrial endothelial nitric oxide synthase (NOS) and sarco/endoplasmic reticulum Ca2+-ATPase levels were lower in the MI group and higher in the losartan group significantly. The atrial inducible NOS and sodium-calcium exchanger levels were higher in the MI and lower in the losartan group significantly. Losartan disrupts collagen fiber formation and prevents the alteration of the tissue eNOS and iNOS levels, which prevent subsequent AF induction.
Visualizing antenna design spaces

This paper describes a long-term project exploring advanced visual interfaces for antenna design. MERL developed three successive prototypes that embodied an evolution towards larger scales and more concrete semantics for visualization of large sets of candidate designs and then winnowing them down. We experimented with multidimensional scaling and then collective line graphs before settling on linked scatterplots to visualize performance in a design space of up to 10 million antennas at a time. In the end, the scatterplot solution was most successful at balancing intelligibility with visualization of the space as a whole. The design allows for adding more 1D or 2D linked feature visualizations if needed, and it smoothly transitions to other "details on demand" views for final tweaking.
Bis{2-hydroxy-N-[2-(2-pyridyl)ethyl]benzamide}copper(I) tetrafluoridoborate

The title complex, [Cu(C14H14N2O2)2]BF4, is a monomeric copper(I) species with linear two-coordinate geometry around the CuI atom. The asymmetric unit contains two half-cations that sit on crystallographic twofold rotation axes. The selected crystal was non-merohedrally twinned by a twofold rotation about an axis normal to the (100) family of planes. The ratio of the twin components refined to 0.4123 (6). Two 2-hydroxy-N-[2-(2-pyridyl)ethyl]benzamide ligands coordinate to each CuI atom via the pyridyl N atom. Intramolecular hydrogen bonding between the phenol OH groups and the amide O atoms imparts rigidity and planarity to the non-coordinating end of the ligand. The cationic complex is linked to the BF4 − anions via hydrogen bonding between the amide NH groups in the cations and BF4 − anions.