Miracle-dz/UniFAR-FTUs huggingface dataset:
Improving depression care in a psychiatry resident psychopharmacology clinic: measurement, monitoring, feedback and education

Objective Better outcomes for major depressive disorder (MDD) are associated with proactive treatment, including timely follow-up, systematic assessment and treatment changes for inadequate improvement. The effectiveness of an intervention to facilitate proactive treatment for MDD in a resident psychopharmacology clinic was studied. Methods A quality improvement program with administrative process changes to improve flow and a 40-week pre/post study to evaluate the effect of education and feedback was conducted. A systematic assessment and reengineered scheduling system were implemented. During the first 20 weeks, baseline data were collected; during the second 20 weeks, feedback to residents and attending psychiatrists about adherence to evidence-based treatment recommendations was added. Results Reengineering our system to improve flow was successful. By linking outcomes collection to completion of billing sheets, outcomes at 90% of visits for MDD throughout the 40-week study was assessed. By centralising our scheduling system, the percentage of active-phase patients with MDD seen for follow-up within 6 weeks was improved from 19% to 59%. In response to feedback, residents did not make significant changes to their overall practice patterns. Patient outcomes did not improve as a result of feedback to residents. Residents did improve their practice patterns for a subset of patients including those without comorbid psychiatric disorders and those whose depressive episodes had lasted <1 year. Conclusions Improving administrative processes for the treatment of patients with MDD resulted in rapid changes that were associated with improvements in the delivery of evidence-based care. Feedback to residents was more difficult and less successful.
Basic research and catch-up in China's high-speed rail industry

The existing literature has not studied the role of basic research in industrial catch-up in developing countries in any depth. This article takes high-speed rail as a case study in order to show how basic research has helped the industry to master imported technology and produce secondary innovations. The role of government is important in terms of coordinating the process of technology importation, digesting imported technology and innovation. The role of the home market is also very important in an era of globalisation to promote innovation in this emerging industry.
The Effects of Race on Professional Football Players' Compensation

Using data on 1,363 NFL players from the 1989 season, the author examines the issue of racial discrimination in professional football. He finds that the difference between white and black players' earnings, with controls for performance and other variables, is small (at most, 4%, favoring whites) and, in most equations, not significantly different from zero. Another finding, however, is that the salaries of white and nonwhite players vary positively with the percentages of whites and nonwhites, respectively, in the metropolitan area in which the team is based —suggesting that some football fans prefer to watch players of their own race, and team owners are willing to pay more to players who, because of their race, will attract a larger audience and bring in greater revenue.
Lomitapide for the treatment of hypertriglyceridemia

ABSTRACT Introduction: Severe genetic forms of hypertriglyceridemia carry a risk of life-threatening pancreatitis and lack available effective treatments. Lomitapide is a microsomal triglyceride transfer protein inhibitor currently approved for treatment of homozygous familial hypercholesterolemia that may be useful in the management of severe hypertriglyceridemia. Areas covered: Published trials of lomitapide that reported plasma triglyceride response were reviewed, as was a case report of a patient with hypertriglyceridemia who was treated for 13 years with lomitapide. ClinicalTrials.gov was also reviewed for any unpublished results and ongoing trials. Expert opinion: Lomitapide demonstrates effective triglyceride lowering and may be a useful treatment for patients with genetic hypertriglyceridemia and recurrent acute pancreatitis who are refractory to traditional treatment. However, long term hepatic safety may be a concern and direct clinical trial-level data are lacking for this indication.
Principles- Versus Rules-Based Accounting Standards: The Fasb's Standard Setting Strategy

In response to criticism of rules-based accounting standards and Section 108(d) of the Sarbanes-Oxley Act of 2002, the SEC proposed principles-based (or ‘objectives-oriented’) standards. We identify several shortcomings with this approach and focus on two of them. First, the format (type) of a standard is dependent on the contents of what the standard regulates. Given the asset/liability approach combined with fair values, we argue that the combination of this measurement concept with principles-based standards is inconsistent because it requires significant guidance for management judgment. Second, we propose the inclusion of a true-and-fair override as a necessary requirement for any format that is more than ‘principles-only’ to deal with inconsistencies between principles and guidance. We discuss the benefits of this override and present evidence from the United Kingdom's experience.
Gene–vitamin D interactions on food sensitization: a prospective birth cohort study

To cite this article: Liu X, Wang G, Hong X, Wang D, Tsai H‐J, Zhang S, Arguelles L, Kumar R, Wang H, Liu R, Zhou Y, Pearson C, Ortiz K, Schleimer R, Holt P, Pongracic J, Price HE, Langman C, Wang X. Gene–vitamin D interactions on food sensitization: a prospective birth cohort study. Allergy 2011; 66: 1442–1448.
Blood pressure from mid‐ to late life and risk of incident dementia

Objective: To determine the association between blood pressure during midlife (40–64 years) to late life (≥65 years) and risk of incident dementia. Methods: This study included 1,440 (758 women, mean age 69 ± 6 years) Framingham Offspring participants who were free of dementia and attended 5 consecutive examinations at 4-year intervals starting at midlife (1983–1987, mean age 55 years) until late life (1998–2001, mean 69 years) and subsequently were followed up for incident dementia (mean 8 years). We determined the effect of midlife hypertension (≥140/90 mm Hg), late life hypertension, lower late life blood pressure (<100/70 mm Hg), persistence of hypertension during mid- to late life, and steep decline in blood pressure from mid- to late life over an 18-year exposure period. Results: During the follow-up period, 107 participants (71 women) developed dementia. Using multivariable Cox proportional hazards models, we found that midlife systolic hypertension (hazard ratio [HR] 1.57, 95% confidence interval [CI] 1.05–2.35) and persistence of systolic hypertension into late life (HR 1.96, 95% CI 1.25–3.09) were associated with an elevated risk of incident dementia. However, in individuals with low to normal blood pressure (≤140/90 mm Hg) at midlife, a steep decline in systolic blood pressure during mid- to late life was also associated with a >2-fold increase in dementia risk (HR 2.40, 95% CI 1.39–4.15). Conclusions: Elevated blood pressure during midlife, persistence of elevated blood pressure into late life, and, among nonhypertensives, a steep decline in blood pressure during mid- to late life were associated with an increased dementia risk in a community-based cohort. Our data highlight the potential sustained cognitive benefits of lower blood pressures in midlife but also suggest that declining blood pressure in older adults with prehypertension or normotension, but not in those with hypertension, may be a risk marker for dementia.
Screen printed flexible capacitive pressure sensor

A novel flexible fully printed capacitive based pressure sensor was designed and fabricated using screen printing technique. Silver (Ag) ink and polydimethylsiloxane (PDMS) were printed on a flexible polyethylene terephthalate (PET) substrate as metallization and dielectric layers, respectively. The capacitive response of the sensor demonstrated a percentage change of 1 % and 3.6 % for compressive forces of 0.2 MPa and 2.4 MPa, respectively when compared to the base capacitance. The response of the pressure sensor is analyzed and presented in this paper.
Management Development Skills in the Hospitality and Tourism Sector: Needs and Issues from a Regional Perspective

Skills development, training and continuing professional education are perceived as critical factors leading to competitiveness of destinations and improvements to quality of tourist experiences. However, they are a perennial issue facing the hospitality and tourism sectors, which are perceived as low-skilled, and where management development is driven by internal promotion. However, most research in this area has focused on skills generally, whereas this study focuses on gaps in, and the need for, management skills specifically. Management skills and training development needs in the sector are analysed in a regional context to highlight barriers and drivers of training uptake locally. The research informs policy on provision of training and concludes for the need to increase communication and routes to training within the sector.
Operator based nonlinear compensation of backlash nonlinearity in spur gear pairs

This paper presents nonlinear compensation of gear driven systems with a backlash nonlinearity. To begin with, a modified model of spur gear pairs including the backlash nonlinearity using dynamic transmission error (DTE) is shown. Then, this paper shows a design scheme of a nonlinear compensator using operator theory. Finally, the effectiveness of the designed compensator is evaluated by numerical simulations.
Aging Induces Changes in the Somatic Nerve and Postsynaptic Component without Any Alterations in Skeletal Muscles Morphology and Capacity to Carry Load of Wistar Rats

The present study aimed to analyze the morphology of the peripheral nerve, postsynaptic compartment, skeletal muscles and weight-bearing capacity of Wistar rats at specific ages. Twenty rats were divided into groups: 10 months-old (ADULT) and 24 months-old (OLD). After euthanasia, we prepared and analyzed the tibial nerve using transmission electron microscopy and the soleus and plantaris muscles for cytofluorescence and histochemistry. For the comparison of the results between groups we used dependent and independent Student's t-test with level of significance set at p ≤ 0.05. For the tibial nerve, the OLD group presented the following alterations compared to the ADULT group: larger area and diameter of both myelinated fibers and axons, smaller area occupied by myelinated and unmyelinated axons, lower numerical density of myelinated fibers, and fewer myelinated fibers with normal morphology. Both aged soleus and plantaris end-plate showed greater total perimeter, stained perimeter, total area and stained area compared to ADULT group (p < 0.05). Yet, aged soleus end-plate presented greater dispersion than ADULT samples (p < 0.05). For the morphology of soleus and plantaris muscles, density of the interstitial volume was greater in the OLD group (p < 0.05). No statistical difference was found between groups in the weight-bearing tests. The results of the present study demonstrated that the aging process induces changes in the peripheral nerve and postsynaptic compartment without any change in skeletal muscles and ability to carry load in Wistar rats.
The Evolution of Australia's Intergovernmental Financial Relations Framework (澳大利亚政府间财政关系框架的演变)

The paper discusses the evolution of Australia's intergovernmental financial relations framework, including developments under Australia's Constitution, and analyses intergovernmental financial transactions under the framework. The methods used to address vertical fiscal imbalance (VFI) and horizontal equity in Australia are discussed and quantitative data on spending across Australian Governments are presented. VFI and horizontal equity are also examined from a historical viewpoint. Finally, some current issues and potential future developments impacting on the distribution of revenue between Australian governments are briefly canvassed. 本文讨论了澳大利亚政府间财政关系框架的演变过程，包括在澳大利亚宪法下此框架的发展情况，并分析了在此框架内的政府间金融交易情况。 同时对用于解决澳大利亚纵向财政不平衡（VFI）和横向财政平衡问题的方法进行了讨论，并列出了澳大利亚各级政府的支出数据。 本文还从历史角度对VFI和横向财政平衡问题进行了研究。 最后，本文还对可能影响澳大利亚政府间财政收入分配的一些现存问题和未来可能的发展方向进行了简要探讨。
Book Review: The Management of Urban Development in Zambia EMMANUEL MUTALE, 2004 Aldershot: Ashgate 284 pp. $99.95/£55.00 hardback ISBN 13 978 0 7546 3596 3 hardback

lives. Through all these considerations, it is surprising that Byrne does not say why a more in-depth and extensive ethnographic study was not chosen to explore the everyday lives of the women. Personal limitations on Byrne’s research are also briefly mentioned in these chapters (her Whiteness, childlessness and middle-class social status), but neither the methodological nor personal limitations discussed are properly dealt with and the core of the work remains unavoidably shaped by them. The core chapters discuss how ‘race’ is talked about and imagined by the 25 mothers in question in the context of their own and their children’s lives in south London (chapter 5); how mothering practices and their social and geographical networks are inclusive and exclusive along racial and class lines (chapter 6); and how national identity (Englishness primarily) is part of the ‘race’ and class-based domestic identities the mothers construct for themselves (chapter 7). Whilst there are some interesting quotes gathered here, much of the analysis is pretty straightforward and does not much extend what we already know or could guess about the matters at hand. The women take their Whiteness for granted, believe racism is a bad thing, but either fail to see racial difference at all or adopt a colour-blind position for fear of otherwise being seen as racist. On the whole, they combine a fearful approach to young Black men on the street with a sense of the desirability of Black culture and masculinity in comparison with the culture and associations that are meant for them as girls from middle-class families and White areas. These are frequently seen as boring and cold and are discussed with elements of self-hatred. Their attitude to racial difference carries over into a quest for schools which have the ‘right mix’ of children, which means fewer Black and working-class kids than White middle-class kids and protection from cultural incursions from non-Christian religions, nonEuropean languages and working-class ‘after-school activities’ and friends. Most of the women identify Britishness and Englishness with Whiteness and use imagined stereotypes to create nostalgic notions of home and country life. Their national and domestic identities are bound together in idealised imaginings of their own childhoods and the past. This is their England. It is narrow and insecure, full of guilt, fear, aspiration, hang-ups, cultural opportunism, a lack of authenticity and aggressive self-advancement. It is an imagined geography but, like all culturally powerful imaginaries, it is dangerous. It has many kinsmen in politics and the media, so Byrne is right to turn her attention to it but she should perhaps be less concerned with its complex interplays and more with its violent backhand.
Synchronization of optical orthogonal codes in optical CDMA systems via simple serial-search method

We analyze, for the first time, the performance of a simple serial-search algorithm for optical code-division multiple access (CDMA) systems using optical orthogonal codes (OOC). For our analysis, we use advanced photon-counting methods and we consider the effect of shot noise and dark current and multi-access interference. We use two approaches for considering the effect of multi-access interference on the performance of the synchronization system. One approach is the general method of considering the average effect of interference. In the other approach, we introduce a new concept for modeling interference; then, with the help of this model, we obtain results that can be regarded as upper and lower bounds on the performance of the synchronization system.
Global quality management programmes: How to make their implementation more effective and less culture dependent

Abstract In this paper, we present a detailed description of the difference between cultural factors and key system factors for implementation of quality management systems. The findings are drawn from observation of the implementation of quality management programmes in numerous factories (electronics, plastic injection, garments, automobile, steel making, etc.) located in Hong Kong/South China, Brazil, Japan and the US. Moreover, we analyze the failure and success factors for multi-cultural implementations. Based on the analysis, we suggest guidelines for a more effective and less culture-dependent implementation methodology.
A 60 GHz down-conversion mixer with variable gain and bandwidth in 130 nm CMOS technology

This paper presents a 60 GHz Gilbert-cell down-conversion mixer in 130 nm RF CMOS technology. In order to enhance the mixer gain and noise performance, inter-stage inductors are used between the switching pairs and the transconductance stage. Also, for the same purpose, the current bleeding/injection technique is adopted which allow us to control both the Conversion Gain (CG) and Bandwidth (BW). Due to the differential mixer structure, two on-chip baluns are used, for the transformation of the single-balanced signal to differential. The baluns show less than 1° and less than 0.2 dB phase and amplitude imbalance, respectively. With a 60 GHz -30 dBm radio-frequency (RF) signal and a 56.8 GHz 2 dBm local-oscillator (LO) signal, the mixer achieves a conversion gain of 15 dB and a noise figure lower than 11 dB. The circuit is biased with a 1.2 V supply voltage and the total power consumption is about 16 mW.
Output Effects of Government Purchases

The theoretical analysis focuses on the distinction between temporary and permanent movements in government purchases. Under plausible conditions, the temporary case involves an output response that is positive, less than one-to-one with the change in government purchases, and larger than that generated by an equal-sized, but permanent, shift in purchase. The equilibrium real rate of return rise in the temporary case, but changes little in the permanent one. Defense purchases are divided empirically into "permanent" and "temporary" components by considering the role of (temporary) wars. No temporary shifts in nondefense purchases were isolated. Empirical results verify an expansionary output effect for temporary purchases that exceeds that of permanent purchases. The results for some other expectational hypotheses are found to be generally supportive of the theory.
Context-Aware Event Stream Analytics

Complex event processing is a popular technology for continuously monitoring high-volume event streams from health care to traffic management to detect complex compositions of events. These event compositions signify critical “application contexts” from hygiene violations to traffic accidents. Certain event queries are only appropriate in particular contexts. Yet state-of-the-art streaming engines tend to execute all event queries continuously regardless of the current application context. This wastes tremendous processing resources and thus leads to delayed reactions to critical situations. We have developed the first context-aware event processing solution, called CAESAR, which features the following key innovations. (1) The CAESAR model supports application contexts as first class citizens and associates appropriate event queries with them. (2) The CAESAR optimizer employs context-aware optimization strategies including context window push-down strategy and query workload sharing among overlapping contexts. (3) The CAESAR infrastructure allows for lightweight event query suspension and activation driven by context windows. Our experimental study utilizing both the Linear Road stream benchmark as well as real-world data sets demonstrates that the contextaware event stream analytics consistently outperforms the state-of-the-art strategies by factor of 8 on average.
Fiscal Interactions of Central City and Suburbs: The Case of Zurich

One possible explanation for the migration from the central city to fiscally independent suburbs is a lack of equivalence between taxation and perceived benefits from local public goods. Spill-outs to suburbs add to this process and may lead to fiscal erosion of the central city. Piecemeal evidence is presented that this problem applies to the city of Zurich. Various possible remedies are discussed, one of which has been applied in Zurich, though not successfully. It is shown theoretically and empirically why this failure occurred. Alternative countermeasures are suggested and an account of how Zurich government officials reacted is supplied.
Strategic Allocation to Premiums in the Equity Market

Investors tend to focus on harvesting the risk premiums offered by traditional asset classes when making their strategic investment decisions. Some recent papers, however, argue that investors should also consider various other premiums for possible inclusion in the strategic asset allocation. Examples of such premiums that have been documented for the equity market are the size, value, momentum and low-volatility effects. In this article, the author demonstrates that the theoretically optimal strategic allocation to these premiums is sizable, even when using highly conservative assumptions regarding their future expected magnitudes. The pros and cons of two ways of obtaining the implied exposures in practice, specifically passively managed index funds versus actively managed quant funds, are also discussed.
Development costs and funding of extra care housing

This article reports findings from an indepth evaluation of extra care housing (a form of assisted living positioned between sheltered housing and care homes) for older people in the UK. The information presented is a significant improvement on that previously in the public domain. The authors conclude that a careful reappraisal of cost components and a more integrated approach across housing, health and social care is required, particularly in a climate of public funding cuts.
Factors influencing the conversion to organic farming in Norway

Determinants of the decision to convert to organic farming methods are examined by applying bivariate analyses and a multinomial logit model to a survey of 1018 Norwegian crop and dairy farmers. The results show that 4% of the conventional respondents plan to convert by 2009, which may imply that the national goal of 10% organically managed area will not be achieved. The analysis indicates that organic farmers, compared to their conventional counterparts, are more likely to have larger farms, more education, be located closer to urban areas, be crop farmers, have 'sustainable and environment-friendly farming' as a goal and hold favourable views about the values of organic farming methods. Even though the farmers who are planning to convert seem to be more business-minded and less organically oriented than the existing organic producers, policies for promoting organic farming which confine itself to financial considerations may miss important factors which prompt farmers to convert.