Miracle-dz/UniFAR-FTUs huggingface dataset:
Improvement of the Sensing Window on a Capacitorless 1T-DRAM of a FinFET-Based Unified RAM

A novel initialization concept is demonstrated to improve the program efficiency of the 1T-DRAM mode of unified random access memory (URAM). The proposed method involves boosting the gate-induced drain leakage current for the generation of excess holes by pretrapping electrons to the nitride layer prior to the activation of 1T-DRAM mode. The proposed initialization concept doubles the current sensing window in 1T-DRAM operation. Due to the potential for soft erasing caused by hot-hole injections into electrons that are trapped in the nitride during the P/E cycling of 1T-DRAM, immunity against soft erasing is confirmed through a dc stress measurement as well.
Generational Differences in the Orientation of Time in Cantonese Speakers as a Function of Changes in the Direction of Chinese Writing

It has long been argued that spatial aspects of language influence people’s conception of time. However, what spatial aspect of language is the most influential in this regard? To test this, two experiments were conducted in Hong Kong and Macau with literate Cantonese speakers. The results suggest that the crucial factor in literate Cantonese people’s spatial conceptualization of time is their experience with writing and reading Chinese script. In Hong Kong and Macau, Chinese script is written either in the traditional vertical orientation, which is still used, or the newer horizontal orientation, which is more common these days. Before the 1950s, the dominant horizontal direction was right-to-left. However, by the 1970s, the dominant horizontal direction had become left-to-right. In both experiments, the older participants predominately demonstrated time in a right-to-left direction, whereas younger participants predominately demonstrated time in a left-to-right direction, consistent with the horizontal direction that was prevalent when they first became literate.
Nucleation, imaging, and motion of magnetic domain walls in cylindrical nanowires

We report several procedures for the robust nucleation of magnetic domain walls in cylindrical permalloy nanowires. Specific features of the magnetic force microscopy (MFM) contrast of such wires are discussed, to avoid the misinterpretation of the magnetization states. The domain walls moved under quasistatic magnetic fields in the range 0.1–10 mT, as evidenced by MFM at remanence at different stages of their motion.
Attentional Capture to a Singleton Distractor Degrades Visual Marking in Visual Search

Visual search is easier after observing some distractors in advance; it is as if the previewed distractors were excluded from the search. This effect is referred to as the preview benefit, and a memory template that visually marks the old locations of the distractors is thought to help in prioritizing the locations of newly presented items. One remaining question is whether the presence of a conspicuous item during the sequential shift of attention within the new items reduces this preview benefit. To address this issue, we combined the above preview search and a conventional visual search paradigm using a singleton distractor and examined whether the search performance was affected by the presence of the singleton. The results showed that the slope of reaction time as a function of set size became steeper in the presence of a singleton, indicating that the singleton distractor reduced the preview benefit. Furthermore, this degradation effect was positively correlated with the degree of conventional attentional capture to a singleton measured in a separate experiment with simultaneous search. These findings suggest that the mechanism of visual marking shares common attentional resources with the search process.
Maintaining consistency between system architecture and dynamic system models with SysML4Modelica

Nowadays many technical products include mechatronic systems that incorporate components from multiple disciplines --- mechanical, electronic, controls and software. In model-based design of mechatronic systems different kinds of models are used to model various system aspects, such as the system structure or its dynamic behavior. This often leads to a process that involves multiple formalisms and is concerned with the coupling of and transformation between models described in these formalisms. In this paper, an approach based on the OMG SysML-Modelica specification is introduced to facilitate the formal definition of dependencies between a system architecture view described in SysML and a continuous system dynamics view defined in Modelica. We discuss the problem of maintaining consistency between these two views. Taking into account the characteristics of the modeling languages, the design workflows, and current modeling tool capabilities, we present the advantages and challenges of modeling the dynamic behavior completely in SysML4Modelica followed by a transformation to Modelica. To overcome the disadvantages, a "mixed-paradigm" approach is proposed in which different parts of the dynamic system behavior are modeled at different levels of abstraction with different formalisms. Finally, an illustrative example is provided which focuses on practical issues related to the usage of SysML4-Modelica.
Online Learning to Rank for Information Retrieval: SIGIR 2016 Tutorial

During the past 10--15 years offline learning to rank has had a tremendous influence on information retrieval, both scientifically and in practice. Recently, as the limitations of offline learning to rank for information retrieval have become apparent, there is increased attention for online learning to rank methods for information retrieval in the community. Such methods learn from user interactions rather than from a set of labeled data that is fully available for training up front. Below we describe why we believe that the time is right for an intermediate-level tutorial on online learning to rank, the objectives of the proposed tutorial, its relevance, as well as more practical details, such as format, schedule and support materials.
THALAMIC NUCLEI OF PITHECUS (MACACUS) RHESUS: I. VENTRAL THALAMUS

The ventral thalamus consists of the hypothalamus and the subthalamus. The nuclear masses of the ventral thalamus form an ancient and unique ensemble of structures which, through their close union with the basal parts of the forebrain on the one hand and with the tegmental region of the midbrain on the other, may be regarded as closely interrelated anatomicophysiologic systems. The mechanism of the hypothalamus is believed to deal with the integration of the internal organic environment with the various experiences of the organism through the medium of the forebrain and the supra-optic decussations; that of the subthalamus, with the generalized primitive motor reactions through the tegmentum and the reticular formation. From the region of the forebrain the olfactory impulses are brought into the hypothalamus by way of the functionally old preoptic region, and from the hypothalamus they are brought into functional relation with the dorsal thalamus and tegmental region
Effect of thiol-activated toxins (streptolysin O, alveolysin, and theta toxin) on the generation of leukotrienes and leukotriene-inducing and -metabolizing enzymes from human polymorphonuclear granulocytes

The generation of leukotrienes (LTC4, LTD4, LTE4, and LTB4; 12-epi-LTB4 isomer) from human granulocytes by thiol-activated toxins (streptolysin O, alveolysin from Bacillus alvei, and theta toxin from Clostridium perfringens) is described. The release occurs under noncytolytic conditions. Although LTB4 is the major component after calcium ionophore stimulation, more LTC4 as compared with LTB4 is released with the toxins. The 5-lipoxygenase pathway of toxin-mediated activation can effectively be inhibited by caffeic acid, a lipoxygenase inhibitor. The toxins also induce the release of leukotriene-metabolizing enzymes such as gamma-glutamyltranspeptidase, which transfers LTC4 into LTD4, and dipeptidase, which metabolizes LTD4, into LTE4. Dipeptidase activity is more pronounced than the gamma-glutamyltranspeptidase activity but still does not reach the levels obtained when cells were triggered with opsonized zymosan.
Incorporating environmental flows into "water stress" indicator 6.4.2: guidelines for a minimum standard method for global reporting

assessment of SDG 6.4. 2 on water stress by contributing data and information on environmental flows (EF). These data are necessary for calculation of the SDG 6.4. 2 indicator on water stress, for which countries are required to submit information to FAO who is custodian of this SDG indicator. The guidelines provide a minimum standard method, principally based on the Global Environmental Flows Information System (GEFIS), which is accessible via http://eflows.iwmi. org, and is the approach that will be used to generate the country EF data that will make up the global 6.4. 2 report. Countries that have more comprehensive and accurate EF data will be able to make use of that data when checking the global dataset produced by FAO and also to add additional details to their Voluntary National report on SDG 6.4. 2.
Long-term efficacy of a rural community-based integrated intervention for prevention and management of chronic obstructive pulmonary disease: a cluster randomized controlled trial in China's rural areas

This study aimed to assess the efficacy of a rural community-based integrated intervention for early prevention and management of chronic obstructive pulmonary disease (COPD) in China. This 18-year cluster-randomized controlled trial encompassing 15 villages included 1008 patients (454 men and 40 women in the intervention group [mean age, 54 ± 10 years]; 482 men and 32 women in the control group [mean age, 53 ± 10 years]) with confirmed COPD or at risk for COPD. Villages were randomly assigned to the intervention or the control group, and study participants residing within the villages received treatment accordingly. Intervention group patients took part in a program that included systematic health education, smoking cessation counseling, and education on management of COPD. Control group patients received usual care. The groups were compared after 18 years regarding the incidence of COPD, decline in lung function, and mortality of COPD. COPD incidence was lower in the intervention group than in the control group (10% vs 16%, <0.05). A decline in lung function was also significantly delayed in the intervention group compared to the control group of COPD and high-risk patients. The intervention group showed significant improvement in smoking cessation compared with the control group, and smokers in the intervention group had lower smoking indices than in the control group (350 vs 450, <0.05). The intervention group also had a significantly lower cumulative COPD-related death rate than the control group (37% vs 47%, <0.05). A rural community-based integrated intervention is effective in reducing the incidence of COPD among those at risk, delaying a decline in lung function in COPD patients and those at risk, and reducing mortality of COPD.
Temporal Resolution in Coevolution Towards Creating the Molecules of Life in Silico

In order to have an artificial life system with high evolvability, we should not only look for life-like organisms, but also the molecules that are able to create them. From this point of view, a new trend has appeared that coevolves machine instruction set and programs together, hoping to reach a more complex life and a higher diversity. However, we argue that simple coevolution of programs and instruction set can become problematic. We suggest using different temporal resolutions between the two evolutions to alleviate the problem. Our simulation results indicate that this approach and improve coevolution's performance. KeywordsAssembler Automata, Coevolution, Tierra, Artificial Life.
Optimizing Typed Feature Structure Grammar Parsing through Non-Statistical Indexing

This paper introduces an indexing method based on static analysis of grammar rules and type signatures for typed feature structure grammars (TFSGs). The static analysis tries to predict at compile-time which feature paths will cause unification failure during parsing at run-time. To support the static analysis, we introduce a new classification of the instances of variables used in TFSGs, based on what type of structure sharing they create. The indexing actions that can be performed during parsing are also enumerated. Non-statistical indexing has the advantage of not requiring training, and, as the evaluation using large-scale HPSGs demonstrates, the improvements are comparable with those of statistical optimizations. Such statistical optimizations rely on data collected during training, and their performance does not always compensate for the training costs.
A Role for the Chromatin‐Remodeling Factor BAZ1A in Neurodevelopment

Chromatin‐remodeling factors are required for a wide range of cellular and biological processes including development and cognition, mainly by regulating gene expression. As these functions would predict, deregulation of chromatin‐remodeling factors causes various disease syndromes, including neurodevelopmental disorders. Recent reports have linked mutations in several genes coding for chromatin‐remodeling factors to intellectual disability (ID). Here, we used exome sequencing and identified a nonsynonymous de novo mutation in BAZ1A (NM_182648.2:c.4043T > G, p.Phe1348Cys), encoding the ATP‐utilizing chromatin assembly and remodeling factor 1 (ACF1), in a patient with unexplained ID. ACF1 has been previously reported to bind to the promoter of the vitamin D receptor (VDR)‐regulated genes and suppress their expression. Our results show that the patient displays decreased binding of ACF1 to the promoter of the VDR‐regulated gene CYP24A1. Using RNA sequencing, we find that the mutation affects the expression of genes involved in several pathways including vitamin D metabolism, Wnt signaling and synaptic formation. RNA sequencing of BAZ1A knockdown cells and Baz1a knockout mice revealed that BAZ1A carry out distinctive functions in different tissues. We also demonstrate that BAZ1A depletion influence the expression of genes important for nervous system development and function. Our data point to an important role for BAZ1A in neurodevelopment, and highlight a possible link for BAZ1A to ID.
Robust audio fingerprint extraction algorithm based on 2-D chroma

Audio fingerprinting, like human fingerprint, identifies audio clips from a large number of databases successfully, even when the audio signals are slightly or seriously distorted. In the paper, based on 2-D, we propose an improved audio fingerprinting extraction algorithm which was proposed by Shazam company. The algorithm uses a combinatorial hashed time-frequency analysis of the audio, yielding unusual properties in which multiple tracks mixed together may each be identified. The results of experiment verify the improvement in the retrieval speed and accuracy.
Molecular Cloning and Expression of cDNA Encoding 3α,7α,12α-Trihydroxy-5β-cholestanoyl-CoA Oxidase from Rabbit Liver*

The steroid side chain cleavage in bile acid formation is catalyzed by liver peroxisomal enzymes (Pedersen, J. I. and Gustafsson, J. (1980) FEBS Lett. 121, 345–348; Kase, F. , Björkhem, I. , and Pedersen, J. I. (1983) J. Lipid Res. 24, 1560–1567). We here describe the cloning and sequencing of a cDNA coding the first of these enzymes, a 3α,7α,12α-trihydroxy-5β-cholestanoyl-CoA oxidase (THCA-CoA oxidase) from rabbit liver peroxisomes. After tryptic digestion of purified protein in a polyacrylamide gel, five peptides were isolated and sequenced. Using two oligonucleotides deduced from the amino acid sequence data, two overlappping clones were isolated from a rabbit liver cDNA library, which together made up a unique cDNA sequence of 2139 base pairs. It contained an open reading frame of 2046 base pairs encoding a protein of 681 amino acids with a molecular mass of 76,209 daltons. All five peptides could be localized within the sequence. Transfection of COS cells with the coding part of the cDNA resulted in a significant expression of THCA-CoA oxidase activity. We were not able to demonstrate 3α,7α-dihydroxy-5β-cholestanoyl-CoA oxidase activity under the same conditions. The obtained sequence showed 73.6% similarity with a proposed rat THCA-CoA oxidase and 81% similarity with a recently reported human branched chain acyl-CoA oxidase, indicating that these three proteins represent the same enzyme. The similarity with rat palmitoyl-CoA oxidase was 41.8%. The C-terminal tripeptide of the protein was SNL, a previously undescribed variant of the main class of peroxisomal targeting signals. Northern blot analysis revealed that the gene is transcribed in liver and kidney, and the major mRNA fraction had a size of approximately 2.6 kilobase pairs.
An Exploratory Study of Physicians' Clinical Judgment

This article describes an exploratory application of social judgment theory (SJT) to analysis of physicians' clinical judgment. The study reflects the interest of the investigators in evaluating the utility of SJT in assessments of an important component of physicians'clinical skills. In the opening section, research on judgment is described relative to other contemporary approaches. A description of the conceptual underpinnings of SJT is provided next, followed by data obtained in a preliminary application of SJT to physicians' clinical judgment in management of ambulatory patients with chronic illness. Discussion of results is restricted to possible interpretations of various measures of clinical judgment. In the closing sections the structure of a broad research agenda is outlined.
Learning Disabilities in the Workplace

DOCUMENT RESUME CE 085 451 Corley, Mary Ann; Tibbetts, John Learning Disabilities in the Workplace: A Professional Development Packet. Session 1 & 2. American Institutes for Research, Washington, DC. Office of Vocational and Adult Education (ED), Washington, DC. Div. of Adult Education and Literacy. 2002-08-00 119p. For full text: http://pro-net2000.org/CM/content_files/ 95.pdf. Guides Non-Classroom (055) EDRS Price MF01/PC05 Plus Postage. Adaptive Behavior (of Disabled); *Adult Students; Attitudes toward Disabilities; Diagnostic Tests; Disability Identification; Employer Employee Relationship; Instructional Materials; *Labor Force Development; *Learning Disabilities; Literacy Education; Normalization (Disabilities); ProfesSional Development; Self Advocacy; Supported Employment; *Teaching Guides; *Vocational Adjustment; Work Environment; *Workplace Literacy *Employment Accommodations (Disabilities); Work Based Learning This field-tested training packet, which was designed for adult literacy providers, contains preparation materials, facilitator's notes, handout masters, and transparency masters for two 3-hour sessions on learning disabilities (LD) in the workplace. (At the end of the first session supported by the packet, participants will be able to do the following: [1] identify a working definition of LD; [2] recognize characteristics of workers with LD and the effect of LD on performance in the workplace; [3] distinguish between screening and diagnostic testing and the uses of each; [4] identify the importance of self-determination, self-advocacy, and disclosure to successful workers with LD; and [5] begin a planning process for helping adults with LD become more successful in the workplace. At the end of the second session, participants will be able to do the following: [1] identify the legal rights of workers with LD; [2] suggest possible workplace accommodations for employees with LD; [3] discuss issues for workers with LD on getting and keeping a job; [4] identify disability-friendly strategies for the workplace; [5] recognize psychosocial issues for employees with LD; [6] present a professional development sequence and lesson plans appropriate for workplace literacy programs; and [7] identify 3 model workplace programs that address issues related to LD.) Includes 14 references and a list of online resources. (MO) Reproductions supplied by EDRS are the best that can be made from the original document. Learning Disabilities in the Workplace A Professional Development Packet
Triptolide markedly attenuates albuminuria and podocyte injury in an animal model of diabetic nephropathy

Triptolide is a major active component of Tripterygium wilfordii Hook F, which exerts marked immunosuppressive, anti-inflammatory and podocyte-protective effects. In this study, the ability of triptolide to inhibit inflammation and attenuate podocyte injury was examined in a rat model of diabetic nephropathy (DN). Type II diabetic rats with DN were treated with triptolide at a dose of 100 μg. kg−1.day−1. Following 8 weeks of triptolide treatment, the urine albumin level, kidney weight/body weight and the number of cells positive for ED-1 (a marker for rat mononuclear macrophages) in the kidney were assessed. The effects of triptolide on podocyte injury and chronic inflammation were analyzed using quantitative polymerase chain reaction (qPCR), western blotting and immunohistochemistry. Following triptolide treatment, the albuminuria in the type II diabetic rats was significantly reduced. Furthermore, the glomerular hypertrophy and foot process effacement were improved, and there was a recovery of the slit diaphragm associated with nephrin and podocin expression. The inflammation in the kidneys was also attenuated. Furthermore, triptolide significantly reduced the expression of transforming growth factor-β1 and osteopontin, and the infiltration of ED-1-positive cells into the kidney. The results demonstrated that triptolide markedly attenuated albuminuria and podocyte injury in the rat model of DN, which may have been correlated with the inhibition of inflammation and macrophage infiltration in the kidneys.
Participation sociale et déficience physique : Favoriser la solidarité et l’inclusion dans les pratiques psychosociales en CSSS

La participation sociale des personnes en situation d’exclusion constitue la finalite principale des politiques sociales adoptees depuis une dizaine d’annees en Occident. Au Quebec, les centres de sante et de services sociaux (CSSS), en raison de la place centrale qu’ils occupent dans le systeme public de sante, sont appeles a promouvoir des interventions novatrices, adaptees aux personnes ayant des besoins particuliers et qui s’accordent avec cet objectif. Les CSSS doivent proposer des pratiques d’intervention sollicitant la capacite d’agir de la personne. Pour cela, la subjectivite de la personne, mais aussi son environnement, doit etre consideree dans l’evaluation et tout au long du processus d’intervention. Dans le programme Deficience physique (DP), parce qu’elles sont maintenues dans un modele de compensation des incapacites, les pratiques psychosociales apparaissent incapables de soutenir les personnes-usageres dans l’atteinte d’un objectif de participation sociale. C’est pourquoi il est necessaire de fournir aux intervenants psychosociaux de premiere ligne un cadre d’analyse et des outils capables de promouvoir des pratiques allant en ce sens.