Miracle-dz/UniFAR-FTUs huggingface dataset:
Mindfulness beyond the Third Wave: The Role of Mindfulness outside the Cognitive-behavioural Tradition

Mindfulness has been defined in cognitive-behavioural terms in the mental health literature despite its broader application by many practitioners. Mindfulness is a complex and often ambiguous concept that has historically been understood and applied in myriad ways depending on the context; thus its application to psychotherapy outside the cognitivebehavioural tradition is not necessarily straightforward, and has not been addressed. This study addressed this gap in the literature through interviews with 9 experienced psychotherapists who integrate mindfulness with non-cognitive-behavioural psychotherapeutic modalities or eclectic psychotherapy. Interviews addressed how participants a) define mindfulness, b) apply it to psychotherapy, and c) the aims of that integration. Data were analyzed via the grounded theory approach. The results depicted mindfulness and its potential applications as broader than its presentation in the mental health literature, and emphasized the role of contexts in shaping conceptualization and application. A broad, context-based model of mindfulness/ psychotherapy integration is proposed. MINDFULNESS BEYOND THE THIRD WAVE iii Acknowledgements I have wanted to undertake this study for several years, but its actual execution was made possible through the ongoing help of many people. I would like to thank my Master’s supervisor, Dr. Roy Moodley for giving me the space to let this project unfold, but always offering guidance as I needed it. I would also like to thank my second reader, Dr. Charles Chen, for the time and consideration he offered this project. Many thanks to the participants for trusting me with their stories, journeys and time – writing this thesis was itself an ongoing mindfulness practice for me, and my conversations with you inspired me to keep practicing. Thank you to my friends at OISE and elsewhere, especially those of you who have also written Master’s theses. You have provided considerable support and inspiration, and you made “It will all be over soon” sound plausible. A big thank you to my family for their willingness to provide feedback on everything from third-grade French homework to graduate essays, for providing me with some of my best research ideas at the dinner table, for always letting me follow my heart, and for teaching me that procrastination is worth less than taking a real summer vacation. Finally, thank you to Rajiv for making me smile and laugh every single day, for making me dinner when I have too much work to do, and for seeing me through two theses now – hopefully only one more to go. MINDFULNESS BEYOND THE THIRD WAVE iv Table of
Rank aggregation via nuclear norm minimization

The process of rank aggregation is intimately intertwined with the structure of skew symmetric matrices. We apply recent advances in the theory and algorithms of matrix completion to skew-symmetric matrices. This combination of ideas produces a new method for ranking a set of items. The essence of our idea is that a rank aggregation describes a partially filled skew-symmetric matrix. We extend an algorithm for matrix completion to handle skew-symmetric data and use that to extract ranks for each item. Our algorithm applies to both pairwise comparison and rating data. Because it is based on matrix completion, it is robust to both noise and incomplete data. We show a formal recovery result for the noiseless case and present a detailed study of the algorithm on synthetic data and Netflix ratings.
Teaching for genetics literacy in the post-genomic era

Abstract Research in genetics and genomics is advancing at a fast pace, and thus keeping up with the most recent findings and conclusions can be very challenging. At the same time these recent findings and conclusions have made necessary a reconceptualization of genes and heredity, both in science and in science education, beyond the mostly gene-centred view of the twentieth century. The teaching of genetics at schools should have a key role in helping students achieve genetics literacy. However, the literature on research in genetics education reports persistent difficulties and misunderstandings. We first consider the public understanding of and the attitudes towards genetics. Then, we review the most recent literature and present the most typical conceptions found among secondary students in various countries, ages and backgrounds. We argue that particular factors such as intuitive thinking, teachers, textbooks, and the media affect students’ development of erroneous or outdated ideas related to genetics. Finally, we suggest how these problems might be addressed in order for genetics teaching at the secondary level to fulfil the aim of contributing to students’ genetics literacy in the current post-genomic era.
Functional traits of woody plants: correspondence of species rankings between field adults and laboratory-grown seedlings?

Abstract Research into interspecific variation in functional traits is important for our understanding of trade-offs in plant design and function, for plant functional type classifications and for understanding ecosystem responses to shifts in species composition. Interspecific rankings of functional traits are a function of, among other factors, ontogenetic or allometric development and environmental effects on phenotypes. For woody plants, which attain large size and long lives, these factors might have strong effects on interspecific trait rankings. This paper is the first to test and compare the correspondence of interspecific rankings between laboratory grown seedlings and field grown adult plants for a wide range of functional leaf and stem traits. It employs data for 90 diverse woody and semi-woody species in a temperate British and a (sub)Mediterranean Spanish flora, all collected according to a strict protocol. For 12 out of 14 leaf and stem traits we found significant correlations between the species ranking in laboratory seedlings and field adults. For leaf size and maximum stem vessel diameter > 50 % of variation in field adults was explained by that in laboratory seedlings. Two important determinants of plant and ecosystem functioning, specific leaf area and leaf N content, had only 27 to 36 and 17 to 31 % of variation, respectively, in field adults explained by laboratory seedlings, owing to subsets of species with particular ecologies deviating from the general trend. In contrast, interspecific rankings for the same traits were strongly correlated between populations of field adults on different geological substrata. Extrapolation of interspecific trait rankings from laboratory seedlings to adult plants in the field, or vice versa, should be done with great caution. Nomenclature: Castroviejo et al. (1986–2000); Stace (1991). Abbreviations: DM/SM = Leaf dry mass/saturated mass ratio; LD = leaf density; PAR = Photosynthetically active radiation; SLA = Specific leaf area; SSLM = Specific saturated leaf mass; SVDmax = Maximum stem vessel diameter.
Attention driven computational model of the auditory midbrain for sound localization in reverberant environments

In this paper, an auditory attention driven computational model of the auditory midbrain is proposed based on a spiking neural network [17] in order to localize attended sound sources in reverberant environments. Both bottom-up attention driven by sensors and top-down attention driven by the cortex are modeled at the level of an auditory midbrain nucleus - the inferior colliculus (IC). Improvements of the model in [17] is made to increase biological plausibility. First, inter-neuron inhibitions are modeled among the IC neurons which have the same characteristic frequency but different spatial response. This is designed to mimic the precedence effect [15] to produce localization results in reverberate environments. Secondly, descending projections from the auditory cortex (AC) to the IC are model to simulate the top-down attention so that focused sound sources can be better sensed in noise or multiple sound source situations. Our model is implemented on a mobile robot with a manikin head equipped with binaural microphones and tested in a real environment. The results shows that our attention driven model can give more accurate localization results than prior models.
Dynamics of Major Histocompatibility Complex Class II Compartments during B Cell Receptor–mediated Cell Activation

Antigen recognition by clonotypic B cell receptor (BcR) is the first step of B lymphocytes differentiation into plasmocytes. This B cell function is dependent on efficient major histocompatibility complex (MHC) class II–restricted presentation of BcR-bound antigens. In this work, we analyzed the subcellular mechanisms underlying antigen presentation after BcR engagement on B cells. In quiescent B cells, we found that MHC class II molecules mostly accumulated at the cell surface and in an intracellular pool of tubulovesicular structures, whereas H2-M molecules were mostly detected in distinct lysosomal compartments devoid of MHC class II. BcR stimulation induced the transient intracellular accumulation of MHC class II molecules in newly formed multivesicular bodies (MVBs), to which H2-M was recruited. The reversible downregulation of cathepsin S activity led to the transient accumulation of invariant chain–MHC class II complexes in MVBs. A few hours after BcR engagement, cathepsin S activity increased, the p10 invariant chain disappeared, and MHC class II–peptide complexes arrived at the plasma membrane. Thus, BcR engagement induced the transient formation of antigen-processing compartments, enabling antigen-specific B cells to become effective antigen-presenting cells.
Effects of Traditional versus Electronic Note Taking in a High School Biology Classroom

________________________________________________________________ iv INTRODUCTION _____________________________________________________________ 1 METHODS AND MATERIALS __________________________________________________ 5 RESULTS ____________________________________________________________________ 9 DISCUSSION ________________________________________________________________ 18 BIBLIOGRAPHY _____________________________________________________________ 22 APPENDIX A: LA/TN ALIGNMENT ____________________________________________ 26 APPENDIX B: UNIT 1 PRE/POST TEST _________________________________________ 33 APPENDIX C: UNIT 2 PRE/POST TEST _________________________________________ 38 APPENDIX D: UNIT 3 PRE/POST TEST _________________________________________ 43 APPENDIX E: UNIT EXAM QUESTION ALIGNMENT _____________________________ 47 APPENDIX F: ENGAGEMENT SURVEY ________________________________________ 49 APPENDIX G: IRB APPROVAL ________________________________________________ 52 VITA _______________________________________________________________________ 53
Chemokines in cutaneous wound healing

Healing of wounds is one of the most complex biological events afterbirth as a result of the interplay of different tissue structures and alarge number of resident and infiltrating cell types. The latter aremainly constituted by leukocyte subsets (neutrophils, macrophages, mastcells, and lymphocytes), which sequentially infiltrate the wound siteand serve as immunological effector cells but also as sources ofinflammatory and growth‐promoting cytokines. Recent data demonstratethat recruitment of leukocyte subtypes is tightly regulated bychemokines. Moreover, the presence of chemokine receptors on residentcells (e.g., keratinocytes, endothelial cells) indicates thatchemokines also contribute to the regulation of epithelialization,tissue remodeling, and angiogenesis. Thus, chemokines are in anexclusive position to integrate inflammatory events and reparativeprocesses and are important modulators of human‐skin wound healing.This review will focus preferentially on the role of chemokines duringskin wound healing and intends to provide an update on the multiplefunctions of individual chemokines during the phases of woundrepair.
Drug–drug interactions with imatinib

AbstractMany patients treated with imatinib, used in cancer treatment, are using several other drugs that could interact with imatinib. Our aim was to study all the drug–drug interactions (DDIs) observed in patients treated with imatinib.We performed 2 observational studies, between the 1st January 2012 and the 31st August 2015 in the Midi-Pyrénées area (South Western France), using the French health insurance reimbursement database and then the French Pharmacovigilance Database (FPVD). A total of 544 patients received at least 1 reimbursement for imatinib. Among them, 486 (89.3%) had at least 1 drug that could potentially interact with imatinib. Paracetamol was the most frequent drug involved (77.4%). Proton pump inhibitors, dexamethasone and levothyroxine, were found in >10% of patients. In the FPVD, among a total of 25 reports of ADRs with imatinib recorded in the Midi-Pyrénées area, 10 (40%) had potential DDIs with imatinib. Imatinib was most frequently prescribed by hospital physicians and drugs interacting with imatinib, by general practitioners.Our study showed that at least 40% of the patients treated with imatinib were at risk of DDIs and that all prescribers must be cautious with DDIs in patients treated with imatinib. During imatinib treatment, we particularly recommend to limit the dose of paracetamol at 1300 mg per day, to avoid the use of dexamethasone, and to double the dose of levothyroxine.
Developmental Exposure to Low-Dose PBDE-99: Effects on Male Fertility and Neurobehavior in Rat Offspring

In utero exposure to a single low dose of 2,2′,4,4′,5-pentabromodiphenyl ether (PBDE-99) disrupts neurobehavioral development and causes permanent effects on the rat male reproductive system apparent in adulthood. PBDEs, a class of flame retardants, are widely used in every sector of modern life to prevent fire. They are persistent in the environment, and increasing levels of PBDEs have been found in biota and human breast milk. In the present study we assessed the effects of developmental exposure to one of the most persistent PBDE congeners (PBDE-99) on juvenile basal motor activity levels and adult male reproductive health. Wistar rat dams were treated by gavage on gestation day 6 with a single low dose of 60 or 300 μg PBDE-99/kg body weight (bw). In offspring, basal locomotor activity was evaluated on postnatal days 36 and 71, and reproductive performance was assessed in males at adulthood. The exposure to low-dose PBDE-99 during development caused hyperactivity in the offspring at both time points and permanently impaired spermatogenesis by the means of reduced sperm and spermatid counts. The doses used in this study (60 and 300 μg/kg bw) are relevant to human exposure levels, being approximately 6 and 29 times, respectively, higher than the highest level reported in human breast adipose tissue. This is the lowest dose of PBDE reported to date to have an in vivo toxic effect in rodents and supports the premise that low-dose studies should be encouraged for hazard identification of persistent environmental pollutants.
Computing-based Self-esteem: The Interplay of Competence and Worthiness

Rachel Vannatta Reinhart, Advisor This concurrent mixed methods study examined how the experiences of being a woman in computing affects her self-esteem over the course of her undergraduate career and into professional employment. Self-esteem was measured using the Rosenberg Self-esteem Scale that applies both competence and worthiness constructs. General (global) self-esteem was compared to self-esteem within the context of computing (computing-based self-esteem). Female attendees (N=546) of ACM-W celebrations of women in computing were invited to complete a Computing Experience Survey (CES). Quantitative and qualitative data were analyzed separately then mixed to validate findings. Quantitative results indicated that women reported significantly lower computing-based self-esteem than global self-esteem. Additionally, competence and worthiness significantly differed within computing-based self-esteem throughout one’s college progression and into the profession. All measures of self-esteem (global, computing-based, competence, and worthiness) improve for professionals. Analysis of open-ended questions illustrated that competence and worthiness are intertwined in computing experiences, and positive and negative experiences often contained a social component. The following conclusions were presented: (1) context matters when measuring self-esteem; (2) competence and worthiness are separate but related dimensions of self-esteem; (3) computingbased self-esteem changes throughout a student’s college career and into the profession; (4) experiences in computing provide explanations for these changes in computing-based selfesteem and shed light on persistence, career faithfulness, and leadership; and, (5) when worthiness is present, it is strongly tied to competence for women in computing.
CACAO - A 64-bit JavaVM Just-in-Time Compiler

This article describes the design and implementation of CACAO, a just in time compiler for Java. The CACAO system translates Java byte code on demand into native code for the ALPHA processor. During this translation process the stack oriented Java byte code is transformed into a register oriented intermediate code. Local variables and stack locations are replaced by pseudo registers eliminating the 32 bit restriction on address types. A fast register allocation algorithm is applied to map the pseudo registers to machine registers. During code generation, eld oosets are computed for proper alignment on 64 bit architectures. Even though the CACAO system has to incur loading and compilation time, it executes Java programs up to 85 times faster than the JDK interpreter, up to 7 times faster than the kaae JIT compiler. It is slightly slower than equivalent C programs compiled at the highest optimization level.
Application of Artificial Neural Networks to Recognize the Relationship Between Corporate Social Responsibility and Financial Performance

The purpose of the present research is to investigate the application of artificial neural networks to recognize the relationship between companies' social responsibility and their financial performance. The data were collected from 20 companies active in the field of pharmaceutical products in Tehran and East Azarbaijan Stock Exchange. The responders to the social responsibility questionnaire consist of the managers of these companies (5 managers from each company). This questionnaire is based on Likert's 5-item scale and measures the 5 dimensions of social responsibility. For gathering information about financial performance, size and risk, we have used financial documents of the firms. Multi-layer perceptron (MLP) neural networks with hyperbolic tangent function trained by feed forward training algorithm were utilized to build the recognition model. The result reveals that the recognition accuracy of the test on the model is greater than that expected by chance. Meanwhile, a set of contribution weights representing the general importance of each independent variable was produced. The advantages of using the model are highlighted. The authors believe that the model is useful and suitable to design internal and external organizational strategies.
Research on SLA information model based on SID

Referring to the international specifications on NGOSS released by TMF (eTOM which specifies the Business Process Framework and SID which describes the Shared Information/Data and SLA which describes the service level agreement in NGOSS knowledge base), and domestic business specifications and status of related to BSS/OSS, the author studied the materials related to the SLA Information Model in OSS, explored the information modeling methods. It includes the correlation content of SLA information model from resource, service to customer.
Does the law alone explain the rise in bankruptcies in XIXth century France

This paper is the first result of a project aiming at understanding the history of bankruptcy law from an empirical economic perspective. By contrast with some proponents of "law and economics" (e.g. La Porta & alii, 1998), we consider that the impact of bankruptcy law on national economic performance cannot be deducted a priori from a simple description of the law, but can only be measured examining actual court practices and economic agents' behaviour. First of all, we believe that an empirical assessment of bankruptcy must start with a better understanding of what determines the proportions of debtor-creditors relationships which end-up in court (contrasting with those settled outside the courts, see Klapper, 2001). This simple question, which is not usually discussed, is a precondition for any interpretation of aggregate bankruptcy statistics. In this paper, we try to measure the impact of the changes in French bankruptcy law in the XIXth century focusing on the behaviour of economic agents as users of bankruptcy law for the sake of finding the best solution to their economic problems. Debtors used bankruptcy law in order to minimize their debt level when facing difficulties in servicing it, but they had to convince their creditors and/or the courts of their good faith, and faced the adverse effects of bankruptcy on their reputation and on the smooth functioning of their business. Creditors used bankruptcy law in order to force their debtors to pay, if they could. We use a new and still incomplete database constructed using both the yearly official statistics produced by the judicial system from 1830 on, and individual bankruptcy files from the Paris commercial court (Tribunal de commerce) archives in order to measure actual practices. The first part of the paper presents the evolution of French bankruptcy law during the XIXth century in its historical context. The second part briefly describes the theoretical model we use in order to understand the choices facing debtors and creditors in the face of financial distress. The last part proposes some major stylized facts concerning bankruptcies during that period and tries to understand their relationship with the legal evolution described before.
Association Analysis of Historical Bread Wheat Germplasm Using Additive Genetic Covariance of Relatives and Population Structure

Linkage disequilibrium can be used for identifying associations between traits of interest and genetic markers. This study used mapped diversity array technology (DArT) markers to find associations with resistance to stem rust, leaf rust, yellow rust, and powdery mildew, plus grain yield in five historical wheat international multienvironment trials from the International Maize and Wheat Improvement Center (CIMMYT). Two linear mixed models were used to assess marker–trait associations incorporating information on population structure and covariance between relatives. An integrated map containing 813 DArT markers and 831 other markers was constructed. Several linkage disequilibrium clusters bearing multiple host plant resistance genes were found. Most of the associated markers were found in genomic regions where previous reports had found genes or quantitative trait loci (QTL) influencing the same traits, providing an independent validation of this approach. In addition, many new chromosome regions for disease resistance and grain yield were identified in the wheat genome. Phenotyping across up to 60 environments and years allowed modeling of genotype × environment interaction, thereby making possible the identification of markers contributing to both additive and additive × additive interaction effects of traits.