Miracle-dz/UniFAR-FTUs huggingface dataset:
Marketized employment services

Purpose – The purpose of this paper is to examine the challenges confronting Christian-based organisations operating in the employment services quasi-market in Australia. It focuses on the tensions that arise for these organisations as they endeavour to deliver services that reflect their distinctive mission and values, while remaining competitive in an environment characterised by the typical market values of commercialism, competition and compliance. Design/methodology/approach – The data on which this paper is based has been derived from 48 semi-structured interviews with church leaders, senior managers and frontline staff in four Christian-based organisations. Findings – The paper demonstrates that the Christian-based organisations under consideration are constrained in their ability to deliver a distinctive and holistic mission. The pressure to survive has resulted in these organisations emulating the business practices of others considered to be more successful in the field. Research limitations/imp.
Cloning, characterization, and DNA sequence of the rfaLK region for lipopolysaccharide synthesis in Salmonella typhimurium LT2

We have cloned and sequenced the rfaL and rfaK genes for lipopolysaccharide synthesis in Salmonella typhimurium LT2 on a 4.28-kb HindIII fragment from the previously described R' factor pKZ3 (S. K. Kadam, A. Rehemtulla, and K. E. Sanderson, J. Bacteriol. 161:277-284, 1985). rfaL is thought to encode a component of the O-antigen ligase, and rfaK is believed to encode the N-acetylglucosamine transferase. The genes were identified by the loss of complementation of prototype rfaL and rfaK mutations after Tn1000 mutagenesis. Translation of the nucleotide sequence predicted sizes of 45.9 and 43.1 kDa for the rfaL and rfaK gene products, respectively. Hydropathy analysis of the rfaL product suggested that it was an integral membrane protein. A third gene, rfaZ, was found to be an 808-bp open reading frame on the pyrE side of rfaK. Insertions into rfaZ reduced rfaK complementation, suggesting cotranscription in the pyrE-cysE direction. The rfaL gene is transcribed in the opposite direction in a separate operon which may also include rfaC. An incomplete open reading frame with homology to an Escherichia coli gene in the same region, rfaY, was found on the pyrE side of rfaZ. Complementation studies with Tn1000 insertions in rfaL showed that rfaL446 and rfaL447 are allelic. With the cloning of the rfaL and -K genes, the order of genes within the rfa cluster at 79 units on the linkage map was found to be cysE-rfaDFCLKZYJIBG-pyrE.
Risks of untreated depression during pregnancy.

QUESTION One of my patients who was taking an antidepressant for major depression is now pregnant and does not wish to take it any more. I believe she needs to continue her medication. She, however, is adamant about stopping it because she believes it would put her baby at risk. Is there evidence that not treating depression during pregnancy puts babies at risk? ANSWER A growing body of literature investigating the effects of not treating depression on mother and developing fetus suggests that untreated depression is associated with adverse fetal outcomes and a higher risk of maternal morbidity, including suicide ideation and attempts, and postpartum depression.
Analysis of earth observation time series to investigate the relation between rainfall, vegetation dynamic and streamflow in the Uele' basin (Central African Republic)

The hydrology of tropical forests play a key role in watershed processes such as soil erosion, streamflow and ground water recharge. However, tropical forests of Africa are least investigated due to the poor network for data acquisition. Earth Observations can fill this gap by providing consistent time series of data. We analyzed trends of rainfall, vegetation index and river water levels derived from satellite data for the Uele sub-basin and we pointed out that rainfall and river water levels are positively correlated only during the dry season when vegetation activities is low. The unexpected low correlation during the season of highest precipitations is due to the role of vegetation, which is characterized by a significant seasonality also in evergreen tropical forests. These results underline the importance of modeling the role of canopy in the interception and evapotranspiration of the available precipitation in order to provide reliable information on stream flow dynamics.
Phased array antenna controlled by neural network FPGA

In this paper, a beam forming network controlled by a neural network implemented on a Field Programmable Gate Array (FPGA) is presented. A Butler matrix feeding the linear antenna array is used to electronically steer the beams in the desired direction. The four microstrip patches and the 4×4 planar Butler matrix are optimized using the Momentum feature of Advance Design System (ADS) for a 2.4 GHz operation. A neural network is designed to control the beam angle. The neural network and the code for the FPGA have been respectively simulated and generated using Matlab Simulink and Xilinx System Generator.
Cutaneous B‐cell lymphoma of nails, pinna and nose treated with chlorambucil

An 83‐year‐old woman presented with primary multifocal cutaneous B‐cell lymphoma, presenting as discrete nodules on the right pinna and nail‐bed of the left middle finger, diffuse swelling and erythema of several other nail‐beds of the fingers and toes, with associated pincer nail deformity and rhinophyma. Because of the involvement of several sites not amenable to radiotherapy, she was treated with oral cyclical chlorambucil with good result.
Correlates of substance misuse in patients with first-episode schizophrenia and schizoaffective disorder.

OBJECTIVE To identify factors associated with substance misuse in first-episode patients with schizophrenia or schizoaffective disorder. METHOD Twenty-seven patients with a past or current history of substance misuse were compared with 91 patients with no history of misuse on demographic and psychopathological measures before being treated for their first episode of psychosis, and on cognitive measures after 6 months of treatment. RESULTS There were no statistically significant differences between groups for sex, schizophrenia subtype, marital status, education, family history of schizophrenia, course of illness, age of onset, baseline symptoms, time to treatment response, medication side effects, attention span, memory and executive functioning. However, dual diagnosis patients were found to have a higher parental social class, better premorbid cognitive functioning, higher IQ and better language skills. CONCLUSION First-episode patients with a history of substance misuse have higher intellectual functioning, which may be associated with higher premorbid socioeconomic status and cognitive functioning.
Broadcast Channel Feedback in Multiple-Antenna Transmitter Cooperation Networks: Accuracy or Consistency?

—We consider the use of broadcast feedback of chan-nel state information (CSI) in multi-cell cooperative networks. The salient feature of this form of feedback lies in the exploitation of the broadcast nature of the wireless medium in order to convey CSI to all transmitters in contrast with other forms of feedback exchange mechanisms relying on inter-transmitter signaling. We show that this particular design approach for feedback naturally leads to a scalable partially distributed precoding framework for multi-cell MIMO networks. A model based on channel quantization is provided to assess the performance of such a system. The analysis exhibits a novel trade-off between feedback consistency and accuracy which is specific to the multi-transmitter cooperation scenario. The optimal trade-off is explored through analysis and numerical simulations.
[Study of biologic effects of simulating static magnetic field of magnetic attachment on human periodontal ligament fibroblasts].

OBJECTIVE To evaluate the biologic effects of simulating static magnetic field of magnetic attachment on human periodontal ligament fibroblasts (HPDLF). METHODS HPDLF were cultured in vitro and exposed to simulating static magnetic fields of magnetic attachments for 4 days with magnetic flux density of 12.5, 125 and 250 mT respectively, while the control group free of additional static magnetic field was also set up. The activities of cellular alkaline phosphatase (ALP) and superoxide dismutase (SOD) were measured with a spectrophotometer, and cell cycle was analyzed by flow cytometry. RESULTS An increase were detected, induced by 250 mT static magnetic field exposure for 4 days in terms of activity of ALP in HPDLF, as compared with the control group (P < 0.05). However, no corresponding effects were found in activity measurements of SOD (P > 0.05). Also there were no statistical differences observed on cell cycle distribution (P > 0.05) or cell proliferation index (P > 0.05) under such static magnetic fields. CONCLUSION The static magnetic fields of magnetic attachment used in this study have improved the activity of ALP, and do little inference to the activity of SOD and the cell cycle distribution.
Political Knowledge and Policy Representation in the States

Political knowledge is central to the success of representative democracy. However, public policy has been shown to follow public opinion even despite low levels of political information in the electorate. Does this mean that political knowledge is irrelevant to policy representation? We consider whether knowledgeable electorates are better able to achieve representative policy outcomes. Using the heterogeneity in the responsiveness of government across the states, we consider how state political knowledge moderates the connection between citizen ideology and the policy outcomes of state government. Using national surveys and multilevel logit with post-stratification, we develop measures of collective political knowledge in the states. We test whether knowledgeable electorates are more likely to secure representative political outcomes than less politically informed constituencies. We find that as state political knowledge increases, so does the correspondence between the preferences of the public and the ideological tenor of state policy outcomes.
Inhibition of the replication of the DNA polymerase M550V mutation variant of human hepatitis B virus by adefovir, tenofovir, L‐FMAU, DAPD, penciclovir and lobucavir

Several nucleoside analogues (penciclovir, lobucavir, dioxalane guanine [DXG], 1‐β‐2,6‐diaminopurine dioxalane [DAPD], L‐FMAU, lamivudine) and acyclic nucleoside phosphonate analogues (adefovir, tenofovir) that are in clinical use, in clinical trials or under preclinical development for the treatment of hepatitis B virus (HBV) infections, were evaluated for their inhibitory effect on the replication of a la‐ mivudine‐resistant HBV variant containing the methionine → valine substitution (M550V) in the polymerase nucleoside‐binding domain. The antiviral activity was determined in the tetracycline‐responsive HepAD38 and HepAD79 cells, which are stably transfected with either a cDNA copy of the wild‐type pregenomic RNA or with cDNA containing the M550V mutation. As expected, lamivudine was much less (≈ 200‐fold) effective at inhibiting replication of the M550V mutant virus than the wild‐type virus. In contrast, adefovir, tenofovir, lobucavir, L‐FMAU, DXG and DAPD proved almost equally effective against both viruses. A second objective of this study was to directly compare the antiviral potency of the anti‐HBV agents in HepG2 2.2. 15 cells (which are routinely used for anti‐HBV drug‐screening purposes) with that in HepAD38 cells. HepAD38 cells produce much larger quantities of HBV than HepG2 2.2. 15 cells, and thus allow drug screening in a multiwell plate format. All compounds were found to be almost equally effective at inhibiting HBV replication in HepAD38 cells (as in HepG2 2.2.15 cells), except for penciclovir, which was clearly less effective in HepAD38 cells.
Comment on "robustness and regularization of support vector machines" by H. Xu, et al., (Journal of Machine Learning Research, vol. 10 pp. 1485-1510, 2009, arXiv: 0803.3490

This paper comments on the published work dealing with robustness and regularization of support vector machines (Journal of Machine Learning Research, vol. 10, pp. 1485-1510, 2009) [arXiv:0803.3490] by H. Xu, etc. They proposed a theorem to show that it is possible to relate robustness in the feature space and robustness in the sample space directly. In this paper, we propose a counter example that rejects their theorem.
Longterm Safety and Efficacy of Tocilizumab in Patients with Rheumatoid Arthritis: A Cumulative Analysis of Up to 4.6 Years of Exposure

Objective. To assess the longterm safety and efficacy of tocilizumab (TCZ) in patients with moderate to severe rheumatoid arthritis (RA). Methods. Patient data were from 5 randomized controlled TCZ trials (n = 4211), their open-label extension phases (n = 3512), and a drug interaction study (n = 23). All randomly assigned patients, regardless of previous RA treatment, were analyzed. Measures of safety included number of adverse events (AE), serious AE (SAE), AE leading to treatment discontinuation, laboratory tests, and deaths. Efficacy measures included American College of Rheumatology (ACR) 20/50/70 responses, tender joint count (TJC), swollen joint count (SJC), ACR core set components, and low disease activity (LDA) or Disease Activity Score in 28 joints (DAS28) remission. ACR/European League Against Rheumatism (EULAR) disease remission was a posthoc exploratory analysis. Results. Total duration of observation was 12,293 patient-years (PY). No new safety signals were identified; infections were the most common AE and SAE. The rate of serious infections was 4.5/100 PY. Improvements from baseline in clinical efficacy, measured as ACR20/50/70 responses, TJC, SJC, ACR core set components, and LDA and DAS28 remission, were generally sustained through at least 216 weeks of followup. ACR/EULAR disease remission was attained by 16.5% (Boolean) and 22.7% (index) of patients at Week 216. Conclusion. TCZ has to date been studied for up to 4.6 years (240 weeks) of treatment in patients with RA. Our analysis reveals a longer-term safety profile consistent with previous observations, no new safety signals, and durable efficacy of TCZ in a large clinical trial program.
The cyanobacterial phytochrome Cph2 inhibits phototaxis towards blue light

We analysed the effects of inactivation of the phytochrome genes cph1 and cph2 on the phototactic migration of the cyanobacterium Synechocystis sp. PCC 6803 under different light qualities. Motility towards white, green, red and far red light was not altered in several independently raised cph1, cph2 and cph1/cph2 double mutants. Blue light (λ = 400–500 nm) did not induce motility in wild‐type and cph1 mutant cells, whereas cph2 and cph1/cph2 double mutants moved towards the blue light. Inhibition of the photosynthetic electron transport by DCMU influenced the motility of cph2 mutants under blue light, but not under white, red and far red light. RNA blot hybridizations did not indicate an altered transcript accumulation of the pilin‐encoding pilA1 gene under blue light. We propose that the Cph2 protein is part of a light‐stimulated signal transduction chain inhibiting the movement of Synechocystis sp. PCC 6803 cells towards blue light.
Eddy current loss analysis in the rotor of permanent magnet traction motor with high power density

For a permanent magnet machine, temperature rise due to the losses in the rotor can affect the performance of the permanent magnet. This is a critical problem for the designers of electric machine. These losses, especially eddy current losses in the conductive part of the rotor, cause heat which cannot easily be mitigate due to the mechanical structure. Therefore, it is very important to consider the losses in the designing step to ensure that the machine operates stably. The most common means of reducing the eddy current losses is to divide them into smaller parts. The analysis for this segmentation structure is only possible in 3D-FEM (Finite Element Method) and though this requires a considerable amount of time during design step. Therefore, it is necessary to calculate the eddy current losses rapidly and accurately. In this paper, an eddy current loss analysis method in the retainer of the permanent magnet machine which has a high power density is proposed. First, the concept of effective conductivity is introduced to solve the segmentation problems not to use 3D-FEM. Also, in order to improve the accuracy of the proposed method, the skin effect which occurs in high speed driving region is considered and a FFT analysis is also performed on the harmonic components of air gap flux density. Finally the thermal analysis result which is based on the loss analysis result is also demonstrated and it is verified to compare with the thermal experimental results.
Early development and innervation of taste bud‐bearing papillae on the rat tongue

Early development of fungiform papillae on the fetal rat tongue was examined: (1) to determine whether morphogenesis of the taste bud‐bearing fungiform papillae is induced by nerve and (2) to study the growth pattern of the two sensory nerves that innervate the papilla. The papillae first appear on the 15th day of gestation (E15; E1 is the day when the dam is sperm positive) in rows parallel to the midline sulcus. There appears to be a medial‐lateral and an anterior‐posterior gradient in the sequence of papilla differentiation. The epithelium of the early papilla resembles a multilayered placode topped by a flattened surface periderm. Close examination of the peridermal cells at the apex of the papillae reveals that the cells have fewer surface microvilli and their cytoplasm is more electron opaque than that of similar cells in interpapillary regions. The basal cells in the placode‐like epithelium differ from those in interpapillary regions in that they are postmitotic and have more mitochondria. At later stages, the papilla acquires a mesenchymal core and nerves grow into the core. Results from organ culture experiments of tongue fragments taken from E14 fetuses indicate that morphogenesis of fungiform papillae is initiated in the absence of sensory nerve influence, but the nerve exerts a trophic effect on their maintenance. The two sensory nerves of the tongue, the chorda tympani and the lingual branch of the trigeminal nerve, enter the tongue mesenchyme at E14 and grow toward the epithelium. By E15 the chorda tympani branches have reached the developing fungiform papillae, by E16 many have entered the papilla, and by E17 they have penetrated the epithelium at the papilla apex. Their fibers are associated exclusively with the cells at the papilla apex, where the taste bud will develop. The trigeminal nerve ramifies beneath the surface of the entire epithelium by E15. Later, it, too, sends branches into fungiform papillae; these ascend along the trunk of the chorda tympani and at E17 terminate in the connective tissue core around the chorda tympani field. The results are compatible with the notion that the tongue epithelium exerts a general tropic effect on growing axons of both sensory nerves, and the epithelial cells of the fungiform papilla apex exert a similar effect to which only the chorda tympani axons are responsive.
3-Carboxy-2-(2-cyclopropylamino-4-methylpyridinium-3-ylamino)pyridinium dinitrate dihydrate

The two benzene rings in the cation of the title compound, C15H18N4O2 2+·2NO3 −·2H2O, are almost perpendicular [dihedral angle = 91.6 (2)°]. In the crystal, the components are linked by O—H⋯O, N—H⋯O and C—H⋯O hydrogen bonds.
Robot Auditory System based on Circular Microphone Array for Home Service Robots

A video display converting circuit for converting scanning patterns from interlaced scanning to sequential scanning of a display device includes an input terminal for receiving an input interlaced scanning video signal having alternating odd and even fields of scanning lines; a first line memory for storing picture elements of the input interlaced scanning video signal in a first line of an odd field; a second line memory for storing picture elements of the input interlaced scanning video signal in a last line of an even field; a plurality of sequential line memories for storing picture elements of the input interlaced scanning video signal in sequence for each scanning line; a demultiplexer for sequentially inputting the picture elements of the input interlaced scanning video signal into each of the first line memory, the second line memory and each of the plurality of sequential line memories in accordance with a write clock signal; a first multiplexer for producing a first output signal by multiplexing between the picture elements of the input interlaced scanning video signal stored in one of the first line memory, the second line memory and selected one from the plurality of sequential line memories in accordance with a read clock signal; an interpolator for interpolating picture elements between adjacent scanning lines of the input interlaced scanning video signal in one of the odd field and the even field to produce interpolated picture elements; a second multiplexer for producing a second output signal representing a sequential scanning video signal by multiplexing between the picture elements contained in the first output signal and the interpolated picture elements provided from the interpolator; and a control section for controlling operations of each of the demultiplexer, the first and second demultiplexers.
Efficient parallel UPGMA algorithm based on multiple GPUs

A phylogenetic tree is used to present the evolutionary relationships among the interesting biological species based on the similarities in their genetic sequences. The UPGMA is one of the popular algorithms to construct a phylogenetic tree according to the distance matrix created by the pairwise distances among taxa. To solve the performance issue of the UPGMA, the implementation of the UPGMA method on a single GPU has been proposed. However, it is not capable of handling the large taxa set. This work describes a novel parallel UPGMA approach on multiple GPUs that is able to build a tree from extremely large datasets. The experimental results show that the proposed approach with 4 NVIDIA GTX 980 achieves an approximately × fold speedup over the implementation of UPGMA on CPU and GPU, respectively.
Oral Biopsies from Patients with Orofacial Granulomatosis with Histology Resembling Crohn's Disease Have a Prominent Th1 Environment

Background: Orofacial granulomatosis (OFG) is an idiopathic inflammatory disorder of children and young adults whose clinical symptoms include swelling of the lips or face, mucosal nodularity (cobblestoning), mucosal tags, hyperplasia of the gingivae, and aphthous oral ulcers. Whether some OFG patients with clinical and histological characteristics resembling Crohn's disease (CD) are a special group (oral CD) or true CD patients with symptoms reaching all the way to the oral mucosa remains to be determined. Methods: In this study oral biopsies from 10 patients with OFG were analyzed for the presence of T cells, T‐cell subsets, B cells, and macrophages, as well as cytokines (IL‐4, IL‐10, IFN‐&ggr;, IL‐12, and TNF‐&agr;), chemokines (RANTES and MIP‐1&agr;), and chemokine receptors (CCR3, CCR5, and CXCR3). For comparison, oral tissues from 7 patients with other granulomatous diseases were included. Results: Compared with the non‐OFG group, the OFG group had raised levels of CD4+ T cells, IFN‐&ggr;, IL‐10, and RANTES but reduced levels of CD68+ macrophages outside the granulomas, whereas within the granulomas the levels of CD3+ and CD4+ T cells and of IFN‐&ggr; were raised, but the levels of IL‐4 were decreased. These data are indicative of a Th1 environment within the oral OFG tissues, which resembles that already observed in gut CD tissues. Conclusions: Therefore, it can be concluded that some OFG patients have both histopathological and immunopathological features that resemble those observed in CD patients.