Miracle-dz/UniFAR-FTUs huggingface dataset:
Is Usage of a Wellness Center Associated with Improved Quality of Life?

Purpose. There is limited documentation regarding the potential quality of life (QOL) benefits associated with use of a worksite wellness center. Therefore, the aim of this study was to examine the relationship between potential QOL change and use of a worksite wellness center during a 12-month period. Design. Analysis of an annual QOL wellness center member survey and wellness center use during a 12-month time period. Setting. A worksite wellness center. Participants. A total of 1151 employee wellness center members, average age of 39.5 years, 69.7% female, and 43.5% reported being overweight. Intervention. Members of the worksite wellness center have access to a range of fitness options, including exercise classes, water aerobics, an indoor track, strength training, and aerobic conditioning equipment. Additionally, nutritional classes are offered, and there is a wellness café. For resiliency, members can participate in wellness coaching or a stress-reduction group program. Method. Participants completed a baseline QOL survey and a second QOL survey 1 year later. An electronic entry system tracked use of the wellness center. Results. Participants were divided into four wellness center use quartiles: low users (less than once every 2 weeks), below-average users, above-average users, and high users (two to three visits per week). High users reported experiencing improvements in their physical QOL (p < .0001) compared with the low users. Additionally, low users experienced a greater decline in their mental QOL (p = .05) compared with high users. Conclusion. In a large sample of employees, use of a wellness center during a 12-month period was associated with benefits for physical QOL. QOL is an important domain of wellness; therefore, in addition to measuring physiologic changes, examining potential QOL changes may be another important outcome measure for wellness centers.
Time to Forget “Just‐in‐Time”? Observations on a Visit to Japan

The study of Japanese manufacture continues to focus on certain elements of the JIT/kanban approach. A recent study tour found that these elements might be broadened to include planning systems and people development initiatives, examples of which are described. The degree to which JIT is a system at all, or has been fully understood in the West, is considered and future research directions proposed.
Substance P primes the formation of hydrogen peroxide and nitric oxide in human neutrophils

Substance P (SP), a neurotransmitter of the central and peripheral nervous system, has been implicated as a mediator of the pulmonary inflammatory response through its stimulatory effects on neutrophils. We investigated the role of SP in priming the production of reactive oxygen species by human neutrophils with the cytochrome c reduction assay and by flow cytometry using the intracellular oxidizable probe dichlorofluorescein. We also investigated SP‐induced formation of nitrite and nitrate as an index of nitric oxide (NO) production. Our results indicate that SP primes two distinct pathways with respect to the induction of reactive oxygen species in the human neutrophil: the production of superoxide anion and hydrogen peroxide by the calmodulin‐dependent NADPH oxidase, and the generation of NO by a constitutive NO synthase. Preincubation of neutrophils with inhibitors of calmodulin and NO synthase diminished the oxidative response in an additive fashion. These results give insight into distinct signal transduction pathways in the SP‐primed neutrophil with respect to the formation of superoxide anion, hydrogen peroxide, and NO. J. Leukoc. Biol. 65: 834–840; 1999.
Speculative boundaries: Chicago and the regulatory history of US financial derivative markets

This paper considers the history of governance and speculation on US derivative markets from their emergence in the middle of the 19th century through their incursion into finance in the late 20th century. It explores the importance of derivatives’ extended ancestry in agricultural markets before analyzing their entanglement with financial markets, which came much later in the 1970s and 1980s. The paper is particularly concerned with the institutional inheritance of a set of legal–regulatory boundaries that prioritized price making and the speculative trading that was necessary to produce a consistent flow of prices. This governance system for derivatives is set in contrast with the governance of securities markets, which during the 1930s became subject to more strict government oversight, particularly with regard to speculative trading. The legal boundaries between these two markets began to deteriorate in the 1970s when the Chicago derivative exchanges applied the speculative logic of agricultural derivative markets to financial instruments. The implications of this are twofold. First the paper argues that market mechanisms and market regulation are analytically inseparable, and ought to be studied as such. Second, employing this approach, the paper argues that US financial derivative markets are originally ‘derivative’ not of New York and the finance sector, but of Chicago and the agricultural sector.
Traditional jamu versus industrial jamu: perceptions and beliefs of consumers in the city of Yogyakarta: what future for traditional herbal medicine in urban Indonesia?

Jamu is the Indonesian traditional herbal medicine practiced in the Indonesian community to maintain good health and to treat diseases. The Jamu industry in Indonesia is predominant among Indonesia's traditional health systems and its popularity is increasing. The paper analyses the different socio-cultural values and perceptions of traditional jamu and industrial jamu among young consumers in the urban environment. It provides insights on the ways in which these traditional practices are perceived to improve the health and well-being of the jamu customers. This paper also aims to give an understanding of the process of internationalisation of the herbal sector in Indonesia and to shed light on the challenges met in exporting the traditional medicinal products in Asia as well as in other western countries. The comprehension of these elements can give some interesting insights on the future evolution of this traditional medicinal system in Asia as well as in other Western countries.
SOCIAL CAPITAL IN A RAINWATER‐HARVESTING PROJECT IN RURAL SOUTH AFRICA

This paper examines social aspects within and amongst households in two selected villages in the Thaba Nchu area in the Free State Province, South Africa. In a semi‐arid environment and low potential for dry croplands, techniques of rainwater harvesting were introduced to enable individual households to improve the level of their food production. This intervention could be seen from a purely biophysical and economic perspective, but the sociocultural domain is just as important for the successful outcome of the intervention. The assumption is that water utilisation and food production are socially embedded in the sense that individuals with different levels of support, are bound together in a situation of risk and uncertainty to collectively find ways to deal with scarcity in resources. The potential for internal conflict and consequent failure or disruption of development projects are real threats to the outcome of any intervention. The paper characterises selected aspects of social capital, namely social support, social networks and cohesion, which are regarded as important factors to consider in the planning and executing of interventions in the field of small‐scale food production. Copyright © 2012 John Wiley & Sons, Ltd.
Fatal atypical T‐cell proliferation associated with Epstein–Barr virus infection

We report the case of a young Caucasian man who presented with polyneuropathy and severe, ultimately fatal, congestive heart failure in the context of a chronic active Epstein–Barr virus (EBV) infection. Post‐mortem examination revealed both monoclonal and polyclonal proliferation of EBV‐positive atypical T lymphocytes within different organs. Predominant infiltration of the nervous system and heart with extensive myocardial scarring accounted for the clinical symptoms. The remarkable features of this case are (i) the occurrence in a Caucasian patient, (ii) the absence of detectable immunodeficiency, and (iii) the myocardial destruction by EBV‐infected monoclonal T cells.
Deafferentation up‐regulates the expression of the mGlu1a metabotropic glutamate receptor protein in the olfactory bulb

Chemical lesion of olfactory neuroepitheium induced an up‐regulation of the mGlu1a metabotropic glutamate receptor protein in the olfactory bulb, as shown by Western blot analysis. At 2 days after the lesion, the increase in the receptor protein was associated with an increase in mGlu1a mRNA levels; in contrast, at longer times after the lesion (16 days), mRNA levels were reduced in spite of the high expression of the receptor protein, perhaps as a result of product‐inhibition of mGlu1 gene expression. Immunohistochemical analysis showed that the increase in mGlu1a induced by olfactory denervation was confined to the glomeruli, which occupy the external portion of the olfactory bulb. Within these structures, mGlu1a receptors are mainly localized on the distal dendrites of mitral cells, which are innervated by the glutamatergic axons of the olfactory nerve.
Autonomy and choice in palliative care: time for a new model?

AIMS This paper will examine understandings of autonomy and choice in relation to palliative and end-of-life care and identify implications for nursing practice. BACKGROUND Autonomy in relation to patient-centred care and advocacy has been identified as a key component of palliative and end-of-life care provision internationally. Understandings of autonomy have emerged in an individualised framework, which may be inadequate in supporting palliative and end-of-life care. DESIGN A critical discussion paper. DATA SOURCES Seminal texts provide a backdrop to how autonomy is understood in the context of palliative care. An overview of literature from 2001 is examined to explore how autonomy and choice are presented in clinical practice. IMPLICATIONS FOR NURSING A model of autonomy based on a 'decision ecology' model may be more applicable to palliative and end-of-life care. Decision ecology aims to situate the individual in a wider social context and acknowledges the relational dimensions involved in supporting choice and autonomy. Such a model recognizes autonomy around wider care decisions but may also highlight the everyday personal aspects of care, which can mean so much to an individual in terms of personal empowerment and dignity. CONCLUSION A 'decision ecology' model that acknowledges the wider social context, individual narratives and emphasises trust between professionals and patients may support decision-making at end of life. Such a model must support autonomy not just at the level of wider decisions around care choice but also at the level of everyday care.
Personal Consumption and Single Persons: A Reply to Kurt Krueger

In the last issue of the Journal of Forensic Economics, Kurt Krueger responded to my earlier comment on his paper on “Personal Consumption and Single Persons. ” In his response, he provided an incorrect characterization of my views. My response clarifies my own position with respect to testimony about personal consumption of single persons.
Towards a Process Model of Corporate Greening

Internal processes of corporate greening have received little scholarly attention. A two-study investigation of consumer-goods producers, implementing environmental management and subject to the 1991 German Packaging Ordinance offers new insights. Findings from Study 1, an exploratory factor analysis, suggest two independent dimensions of environmental management: Policy Commitment and Approach to Implementation. We expand traditional strategic change models, and generate a typology of four types of corporate greening: Deliberate Reactive, Unrealized, Emergent Active, and Deliberate Proactive greening. These are fleshed out with four known cases in Study 2. Alternative conceptual scenarios, developed to explain those types with inconsistent values for Policy Commitment and Implementation, point to new directions for research on the dynamics of internal processes of corporate greening. We conclude with implications for corporate social performance and strategic process models.
Explaining the Performance of Domestic Equity Mutual Funds

Using data over 1992Q1–2000Q1, the authors evaluate the ability of various publicly available mutual fund attributes to explain subsequent domestic equity fund returns. Risk and investment style explain a great deal of the variability in mutual fund returns during this period, but the relationship between these attributes and future fund returns changes dramatically from quarter to quarter. Past performance and expenses explain less of the variability in subsequent fund returns, through relationships that are much more consistent over the period. The recommendation is to choose an asset allocation based on the investor's risk tolerance and implement it using funds with good past performance and low expenses. Investors who are not market or style timers should diversify across fund styles, as good past performance and low expenses alone are not powerful enough to offset the damage from investing heavily in a style that goes out of favor.
CORONARY ARTERY DISEASE Original Studies Early Beneficial Effects of Drug-Eluting Stents in Vein Grafts Wane During Long Term Follow-Up: A Case–Control Study

Objectives: The aim of the study was to compare outcomes of drug-eluting stents (DES) versus bare-metal stents (BMS) in saphenous vein graft (SVG) interventions in a case–control study with a long-term follow-up. Background: Safety and efficacy of DES in SVG interventions are still controversial. Methods: We performed a multicenter registry assessing clinical outcomes with DES vs. BMS. We included 311 patients (239 men, age 68 6 8 years) who underwent percutaneous coronary interventions (PCI) of SVG lesions with DES (n 5 138) or BMS (n 5 173) with a 2-year follow-up. Results: The two groups were similar for age, sex, main risk factors, incidence of diabetes, use of IIb/IIIa antagonists, use of aspiration devices or filters, number of stents, and total stent length. Overall, at 9 months follow-up incidence of major adverse cardiac events (MACE) and target vessel revascularization (TVR) were significantly lower in the DES group compared with the BMS group (10.9% vs. 22.0%, P 5 0.014 and 8.7% vs. 19.1% in DES and BMS respectively, P 5 0.015), while there was no significant difference in incidence of myocardial infarction (5.1% vs. 5.2%, P 5 0.96) or death (2.2% vs. 4%, respectively, P 5 0.54). However, at 24-month follow-up incidence of MACE was 29.7% in the DES group and 37.0% in BMS group (P 5 0.29); incidence of TVR (23.2% vs. 28.9% P 5 0.39), myocardial infarction (9.4% vs. 9.2%), death (7.2% vs. 6.9%) were also similar in the two groups. Conclusions: Although DES appear safe, our findings suggest that the early benefit of DES in SVG may rapidly wane during long-term follow-up. VC 2012 Wiley Periodicals, Inc.
Equity in Whom Gets Studied: A Systematic Review Examining Geographical Region, Gender, Commodity, and Employment Context in Research of Low Back Disorders in Farmers

ABSTRACT Farmers are at high risk of having low back disorders (LBDs). Agriculture employs half the global workforce, but it is unclear whether all farming populations are represented equitably in the LBD literature. This systematic review quantifies the number and quality of research studies by geographical region, agricultural commodity, and farmer characteristics. MEDLINE, Web of Science, CINAHL, Scopus, and Embase databases were searched using conceptual groups of search terms: “farming” and “LBD. ” Screening and extraction were performed by two researchers in parallel, then reconciled through discussion. Extracted study characteristics included location of study; commodity produced; worker sex, ethnicity, and migration status; type of employment; and study quality. These were compared with agricultural employment statistics from the International Labour Organization and World Bank. From 125 articles, roughly half (67) did not specify the employment context of the participants in terms of migration status or subsistence versus commercial farming. Although in many regions worldwide women make up the bulk of the workforce, only a minority of low back disorder studies focus on women. Despite the predominance of the agricultural workforce in developing nations, 91% of included studies were conducted in developed nations. There was no significant difference in study quality by geographic region. The nature of the world’s agricultural workforce is poorly represented by the literature when it comes to LBD research. If developing nations, female sex, and migrant work are related to increased vulnerability, then these groups need more representation to achieve equitable occupational health study.
Vote Bying I: General Elections

We examine the consequences of vote buying, assuming this practice were al- lowed and free of stigma. Two parties compete in a binary election and may purchase votes in a sequential bidding game via up-front binding payments and/or campaign promises (platforms) that are contingent upon the outcome of the elec- tion. We analyze the role of the parties' and voters' preferences in determining the winner and the payments to voters.
Human GATA‐3: a lineage‐restricted transcription factor that regulates the expression of the T cell receptor alpha gene.

In addition to its role in the recognition of foreign antigens, the T cell receptor (TCR) alpha gene serves as a model system for studies of developmentally‐regulated, lineage‐specific gene expression in T cells. TCR alpha gene expression is restricted to cells of the TCR alpha/beta+ lineage, and is controlled by a T cell‐specific transcriptional enhancer located 4.5 kb 3′ to the C alpha gene segment. The TCR alpha enhancer contains four nuclear protein binding sites called T alpha 1‐T alpha 4. In this report we describe the identification and characterization of a novel human cDNA, hGATA‐3 that binds to the T alpha 3 element of the human TCR alpha enhancer. hGATA‐3 contains a zinc finger domain that is highly related to the DNA‐binding domain of the erythroid‐specific transcription factor, GATA‐1, and binds to a region of T alpha 3 that contains a consensus GATA binding site (AGATAG). Northern blot analyses of hematopoietic cell lines demonstrate that hGATA‐3 is expressed exclusively in T cells. Overexpression of hGATA‐3 in HeLa cells or human B cells specifically activated transcription from a co‐transfected reporter plasmid containing two copies of the T alpha 3 binding site located upstream of the minimal SV40 promoter. Taken together these results demonstrate that hGATA‐3 is a novel lineage‐specific hematopoietic transcription factor that appears to play an important role in regulating the T cell‐specific expression of the TCR alpha gene.
Women’s Experience of Violence During Stalking by Former Romantic Partners

This study investigated female experiences of physical violence during stalking by a former romantic partner. It aimed to identify factors that were predictive of such stalking violence. Two hundred and twenty female undergraduates who defined themselves as victims of stalking following the dissolution of a romantic relationship completed a short questionnaire. From their responses, 11 predictor variables were considered. These were self-reported relationship experiences of physical and sexual violence, intentional damage to participant’s property, partner jealousy, isolation, monitoring, criticism and insults by the former partner, former partner’s drug and alcohol abuse, and specific threats of violence while being stalked. The dependent variable in the study was whether stalking violence occurred; 35.9% (79/220) of participants experienced stalking violence. Logistic regression analysis revealed that there were statistically significant independent associations between threats, partner jealousy, and former partner drug abuse and stalking violence.
Clinical efficacy of reversible and selective inhibitors of monoamine oxidase A in major depression

This article reviews efficacy studies of the reversible selective inhibitor of monoamine oxidase A (MAO‐A) nioclobemide, which has now received extensive evaluation. Placebo‐controlled trials have shown it clearly to be effective. In comparisons with tricyclic and similar antidepressants and with serotonin reuptake inhibitors, it has been found of equal efficacy to these standard drugs. Because of previous suggestions that older MAO inhibitors are particularly effective in depressions characterized as alypical, the effects in subtypes are of particular interest. The evidence indicates that moclobemide is effective in typical severe depression with melancholia rather than being limited to less lypical subtypes.
Political Pressures in the Life of Ethicists: Opportunities for Professional Moral Development

Abstract: This symposium highlights the political conflicts, clashing views, ethically problematic laws and regulations and competing pressures that ethicists encounter in professional practice. Viewed through the lens of Rest’s Four Component Model of Morality, the stories illustrate the capacities required for effective professional practice: Are ethicists sensitive to the full range of ethical issues? Are they equipped to reason through complex situations in a principled manner? Do they have a strong ethical and professional identity? Do they have the perseverance, character, and implementation abilities needed to translate their convictions into action? The stories also reveal unsettled problems with respect to the role and responsibilities of the ethicist in contemporary society.
Ground referencing GRACE satellite estimates of groundwater storage changes in the California Central Valley, USA

There is increasing interest in using Gravity Recovery and Climate Experiment (GRACE) satellite data to remotely monitor groundwater storage variations; however, comparisons with ground‐based well data are limited but necessary to validate satellite data processing, especially when the study area is close to or below the GRACE footprint. The Central Valley is a heavily irrigated region with large‐scale groundwater depletion during droughts. Here we compare updated estimates of groundwater storage changes in the California Central Valley using GRACE satellites with storage changes from groundwater level data. A new processing approach was applied that optimally uses available GRACE and water balance component data to extract changes in groundwater storage. GRACE satellites show that groundwater depletion totaled ∼31.0 ± 3.0 km3 for Groupe de Recherche de Geodesie Spatiale (GRGS) satellite data during the drought from October 2006 through March 2010. Groundwater storage changes from GRACE agreed with those from well data for the overlap period (April 2006 through September 2009) (27 km3 for both). General correspondence between GRACE and groundwater level data validates the methodology and increases confidence in use of GRACE satellites to monitor groundwater storage changes.