Miracle-dz/UniFAR-FTUs huggingface dataset:
Weakly-coupled ontology integration of P2P database systems

We present the basic elements of a new semantics that captures the modular structure of a data-intensive Peer-to-peer (P2P) system, and opens up the possibility of effective query answering techniques. One of the basic characteristics of peers in our approach is that they (possibly) encapsulate an ontology of a data integration system in order to deal with incomplete Web-based information, and to offer a rich ontology interface to their clients. Each peer acts at the same level with respect to the others, with no direct mapping between them, and no unifying structure above them. Based on the above ideas, we define a general framework for P2P systems, and we describe an incremental algorithm for answering conjunctive queries posed to one peer. The contributions to the query answer of any peer are given by the certain answers that such peer provides. We show that the algorithm computes its answers according to a generalized epistemic modal S5 logic, where frames are partitioned according to the structure of peers. This new semantics for P2P systems models a kind of intensional mapping that is fundamentally different from the GLAV (Global and Local As View) extensional mappings, traditionally adopted in data integration.
Design of Ring Couplers for Arbitrary Power Division With 50 $\Omega$  Lines

A new 0°/180° ring coupler structure is proposed for the arbitrary power division ratios. The proposed coupler consists only of 50 Ω transmission lines with the simple ring structure. The electrical lengths of the 50 Ω branches are adjusted to obtaining any desired values of the power division ratio without changing the impedance. A very wide range of power division ratios can be obtained easily with the simple 50 Ω line based ring structure.
Individual differences in schizotypal personality traits correlate with amphetamine induced dopamine release in striatal and extra-striatal brain regions

Objective—Schizotypal personality traits are associated with schizophrenia spectrum disorders. Individuals with schizophrenia spectrum disorders demonstrate increased dopamine transmission in the striatum. We sought to determine if individual differences in normal variation in schizotypal traits correlate with dopamine transmission in the striatum and extra-striatal brain regions. Method—63 healthy individuals with no history of psychiatric illness completed the Schizotypal Personality Questionnaire and underwent positron emission tomography (PET) imaging with [18F]fallypride at baseline and after administration of oral (0.43 mg/kg) d-amphetamine. Dopamine release, quantified by subtracting each subject’s d-amphetamine scan from their baseline scan, was correlated with Schizotypal Personality Questionnaire total and factor scores using region-of-interest and voxel-wise analyses. Results—Dopamine release in the striatum positively correlated with overall schizotypal traits. The association was especially robust in the associative sub-division of the striatum. Voxel-wise analyses identified additional correlations between dopamine release and schizotypal traits in the left middle frontal gyrus and left supramarginal gyrus. Exploratory analyses of Schizotypal Personality Questionnaire factor scores revealed correlations between dopamine release and disorganized schizotypal traits in the striatum, thalamus, medial prefrontal cortex, temporal lobe, insula, and inferior frontal cortex. Conclusions—The association between dopamine signaling and psychosis phenotypes extends to individual differences in normal variation in schizotypal traits and involves dopamine transmission in both striatal and extra-striatal brain regions. D-amphetamine induced dopamine release may be a useful endophenotype for investigating the genetic basis of schizophrenia spectrum disorders. Address Correspondence to: Neil D. Woodward, Ph.D., Assistant Professor of Psychiatry, Vanderbilt Psychiatric Hospital, Suite 3057, 1601 23rd Ave. S. , Nashville, TN 37212, Phone: 615.322. 8361, Fax: 615.936. 3563. A symposium abstract based on this work was presented at the 65th Annual Meeting of the Society of Biological Psychiatry in New Orleans, May 20-22, 2010. Conflict of interest statement: Dr. Robert M. Kessler holds a patent for the use of Fallypride in humans, although there are no plans currently to use it commercially. None of the remaining authors report any conflicts of interest. NIH Public Access Author Manuscript Am J Psychiatry. Author manuscript; available in PMC 2013 September 11. Published in final edited form as: Am J Psychiatry. 2011 April ; 168(4): 418–426. doi:10.1176/appi.ajp. 2010.10020165. N IH PA Athor M anscript N IH PA Athor M anscript N IH PA Athor M anscript
Centrality Approach for Community Detection in Large Scale Network

Identifying communities in social network plays an important role in predicting behavior of the complex network. Real world systems in social network can be modeled as a graph structure, where nodes represents the social entities and edges represents the relationships among the entities. Usually nodes inside a community are having similar kinds of properties and most of them are influence by one or more central nodes in the network. Hence centrality principle can be adapted for efficiently discovery of communities. In this paper, an attempt has been made for community detection using central nodes of the network. Discovering central nodes in large scale network is a challenging task due to its huge complex structure. Central nodes have been been identified using map reduce paradigm in order to carry out the computation in distributed manner. The process of discovering communities is then carried out using the identified central nodes. Experimental evaluation shows that the proposed method for community detection provides better performance in term of both accuracy and time complexity.
Five Lenses for Designing Exertion Experiences

The field of HCI has increasingly looked at ways to support the physically active human being, however, new work suggests that the field has only begun to understand the many virtues of exertion. To further the field, we present a set of five design lenses extended primarily from sports philosophy literature to help approach exertion not just as a means of deferring death, but also as an opportunity for personal growth. The lenses facilitate learning how to appreciate a void (Reverie), welcome pleasure (Pleasure), become humble (Humility), as well as be fearful and excited simultaneously (Sublime), whilst being more carefully aware of one's own body (Oneness). Using these lenses, we articulate associated technology opportunities through related work as well as our own craft knowledge. With our work, we aim to support designers who want to facilitate the many virtues of exertion so that ultimately more people profit from the many benefits of being physically active.
RNF: a general framework to evaluate NGS read mappers

Motivation: Read simulators combined with alignment evaluation tools provide the most straightforward way to evaluate and compare mappers. Simulation of reads is accompanied by information about their positions in the source genome. This information is then used to evaluate alignments produced by the mapper. Finally, reports containing statistics of successful read alignments are created. In default of standards for encoding read origins, every evaluation tool has to be made explicitly compatible with the simulator used to generate reads. Results: To solve this obstacle, we have created a generic format Read Naming Format (Rnf) for assigning read names with encoded information about original positions. Futhermore, we have developed an associated software package RnfTools containing two principal components. MIShmash applies one of popular read simulating tools (among DwgSim, Art, Mason, CuReSim, etc.) and transforms the generated reads into Rnf format. LAVEnder evaluates then a given read mapper using simulated reads in Rnf format. A special attention is payed to mapping qualities that serve for parametrization of Roc curves, and to evaluation of the effect of read sample contamination. Availability and implementation: RnfTools: http://karel-brinda.github. io/rnftools Spec. of Rnf: http://karel-brinda.github. io/rnf-spec Contact: karel.brinda@univ-mlv.fr
Immune Infiltration and Clinical Outcome in Non-Small Cell Lung Cancer

Recent data indicate that tumor-associated neutrophils (TANs) serve a dual role in tumor progression and regression. CD66b is a neutrophil marker and has been associated with patient outcome in various cancers. However, its clinical impact in non-small cell lung cancer (NSCLC) remains controversial. 536 NSCLC patients, of which 172 harbored lymph node metastases, were included in this study. Tissue microarrays were constructed and multiplexed immunohistochemistry of CD66b, CD34 and pan-keratin was performed to evaluate the localization and quantity of CD66b+ TANs. High intratumoral CD66b+ TANs density in squamous cell carcinoma (SCC) subgroup was an independent positive prognosticator for disease-specific survival (P = 0.038). In contrast, high intratumoral TANs density was an independent negative prognostic factor in the adenocarcinoma (ADC) subgroup (P= 0.032). Likewise, in ADC patients with lymph node metastases, high level of intratumoral TANs was associated with poor prognosis (P = 0.003). Stromal CD66b+ TANs were not associated with outcome of NSCLC patients. In conclusion, CD66b+ TANs show diverging prognostic effect in NSCLC patients according to histological subgroups. The presence of CD66b+ TANs could prove pivotal for development of an immunoscore in ADC NSCLC patients.
A Physical/Virtual Carrier-Sense-Based Power Control MAC Protocol for Collision Avoidance in Wireless Ad Hoc Networks

A kind of hidden terminal problem, called the POINT problem, which is caused by the expansion of the interference range of the receiver due to the controlled transmission power of the sender, is deemed a notorious problem in wireless ad hoc networks. This paper utilizes physical and virtual carrier-sensing schemes to avoid the POINT problem. We analyze the relationships among the transmission range, the carrier-sensing range, and the interference range in case power control is adopted, and based on the analyzed results, we propose four mechanisms to prevent the POINT problem from occurring in wireless ad hoc networks. This paper further analyzes the superiority of each mechanism under certain situations and proposes an adaptive range-based power control (ARPC) MAC protocol to make use of the advantages of the four mechanisms to avoid the POINT problem from happening. The proposed protocol cannot only prevent collisions caused by the POINT problem, but it can also reduce the energy consumption of STAs. Simulation results also verify the advantages of the proposed protocol.
The apoB/apoA‐I ratio: a strong, new risk factor for cardiovascular disease and a target for lipid‐lowering therapy – a review of the evidence

During the last several years interest has focused on the importance of the lipid‐transporting apolipoproteins – apoB transports all potentially atherogenic very low‐density lipoprotein (VLDL), intermediate‐density lipoprotein (IDL) and LDL particles, and apoA‐I transports and acts as the major antiatherogenic protein in the HDL particles. The evidence for the apoB/apoA‐I ratio being a strong, new risk factor for cardiovascular (CV) disease and a target for lipid‐lowering therapy is reviewed. Results from clinical prospective studies and lipid‐lowering trials in healthy subjects and in patients with different clinical manifestations of atherosclerosis are reported. Risk of nonfatal and fatal myocardial infarction and stroke, and manifestations of atherosclerosis documented by angiographic, ultrasound and other techniques has been related to conventional lipids and apolipoproteins (apo). The cholesterol balance determined as the apoB/apoA‐I ratio has repeatedly been shown to be a better marker than lipids, lipoproteins and lipid ratios. The results indicate that the apoB/apoA‐I ratio is a simple, accurate and new risk factor for CV disease – the lower the apoB/apoA‐I ratio, the lower is the risk. Guidelines should be developed in order to recognize the important clinical risk information embedded in the apoB/apoA‐I ratio.
Confidentiality enforcement by hybrid control of information flows

An information owner, possessing diverse data sources, might want to offer information services based on these sources to cooperation partners and to this end interact with these partners by receiving and sending messages, which the owner on his part generates by program execution. Independently from data representation or its physical storage, information release to a partner might be restricted by the owner's confidentiality policy on an integrated, unified view of the sources. Such a policy should even be enforced if the partner as an intelligent and only semi-honest attacker attempts to infer hidden information from message data, also employing background knowledge. For this problem of inference control, we present a framework for a unified, holistic control of information flow induced by program-based processing of the data sources to messages sent to a cooperation partner. Our framework expands on and combines established concepts for confidentiality enforcement and its verification and is instantiated in a Java environment. More specifically, as a hybrid control we combine gradual release of information via declassification, enforced by static program analysis using a security type system, with a dynamic monitoring approach. The dynamic monitoring employs flow tracking for generalizing values to be declassified under confidentiality policy compliance.
The Road We Travelled: Discovery, Choreography, and Significance of Brain Replaceable Neurons

Abstract: Neurons are constantly added to the telencephalon of songbirds. In the high vocal center (HVC), where this has been studied, new neurons replace older ones that died. Peaks in replacement are seasonal and affect some neuronal classes but not others. Peaks in replacement coincide with peaks in information acquisition. The new neurons are produced by division of cells in the wall of the lateral ventricle. Where studied closely, the neuronal stem cells proved to be radial glia. Life expectancy of the new neurons ranges from weeks to months. New neuron survival is regulated by vacancies, hormones, and activity. The immediate agent of new neuron survival is, in some cases, brain‐derived neurotrophic factor (BDNF). The effect of BDNF is maximal 14‐20 days after the cells are born, when they are establishing their connections. These observations are now being extended to other vertebrates and may apply, to varying degrees, to all of them. The function of neuronal replacement in healthy adult brain remains unclear. If synaptic number and efficacy sufficed as mechanisms for long‐term memory storage and could be adjusted again and again to incorporate new memories, then neuronal replacement would seem unnecessary. Since it occurs, it seems reasonable to suppose that replacement serves to maintain learning potential in a way that could not be done just by synaptic change. Long‐term memories may be encoded by long‐term changes in gene expression akin to a last step in cell differentiation. If so, neuronal replacement may be the adult brain's way of striking a balance between limited memory space and the need to acquire new memories. The testing of this hypothesis remains in the future. This chapter tells how neuronal replacement was discovered in the adult songbird brain.
A Feasibility Study of Wrist-Worn Accelerometer Based Detection of Smoking Habits

Cigarette smoking is one of the major causes of lung cancer, and has been linked to a large amount of other cancer types and diseases. Smoking cessation, the only mean to avoid these serious risks, is hindered by the ease to ignore these risks in day-to-day life. In this paper we present a feasibility study with smokers wearing an accelerometer device on their wrist over the course of a week to detect their smoking habits based on detecting typical gestures carried out while smoking a cigarette. We provide a basic detection method that identifies when the user is smoking, with the goal of building a system that provides an individualized risk estimation to increase awareness and motivate smoke cessation. Our basic method detects typical smoking gestures with a precision of 51.2% and shows a user-specific recall of over 70% - creating evidence that an unobtrusive wrist-watch-like sensor can detect smoking.
Assessing outcomes through congruence of course objectives and reflective work

Introduction: Course outcomes have been assessed by examining the congruence between statements of commitment to change (CTCs) and course objectives. Other forms of postcourse reflective exercises (for example, impact and unmet‐needs statements) have not been examined for congruence with course objectives or their utility in assessing course outcomes. This study assessed the congruence of course objectives and statements of commitment to change, effects on practice, unmet‐needs, and the utility of supplementing CTCs with other forms of reflective work in course evaluations. Methods: A 3‐module course on Alzheimer's disease and other dementias provided end‐of‐course CTC statements, follow‐up data, and statements of effects on practice and unmet needs. Statements were aligned to module objectives and analyzed descriptively. Results: Of the 932 physicians who registered for 1 of the 3 modules, 404 provided CTCs, 302 provided impact statements, and 265 provided unmet‐needs statements. Sixty percent of the CTCs could be assigned to an objective for their module, and between 14% and 25% of CTCs were assigned to objectives for another module. Three‐quarters of CTCs were fully or partially implemented. Physicians did not have an opportunity to implement the new content in 70% of nonimplemented CTCs. Fewer impact and unmet‐needs statements were congruent with course objectives than CTCs. Conclusions: Commitment‐to‐change statements had more congruence with objectives than did impact or unmet‐needs statements. These latter statements, particularly those that could not be assigned to an objective, may reinforce and supplement the information provided by CTC analyses.
CPW-fed circular ring monopole antenna

A novel design of circular ring monopole antenna fed by coplanar waveguide (CPW) is presented and studied for ultra wideband (UWB) applications in this paper. Printed on a dielectric substrate and fed by a 50/spl Omega/ CPW on the same side of the substrate, a circular ring monopole can operate over an ultra wide frequency range with omni-directional radiation patterns over the entire bandwidth. Good agreement has been obtained between the simulation and experiment.
The central neural connections of the area postrema of the rat

We applied the neuroanatomical tracers cholera toxin‐horseradish peroxidase and wheat germ agglutinin‐horseradish peroxidase to investigate the neural connections of the area postrema (AP) in the rat. We find that the AP projects to the nucleus of the solitary tract (NTS) and dorsal motor nucleus of the vagus bilaterally both rostral and caudal to obex; the nucleus ambiguus; the dorsal aspect of the spinal trigeminal tract and nucelus and the paratrigeminal nucleus; the region of the ventrolateral medullary catecholaminergic column; the cerebellar vermis; and a cluster of structures in the dorsolateral pons which prominently include a discrete set of subnuclei in the lateral parabrachial nucleus. The major central afferent input to the area postrema is provided by a group of neurons in the paraventricular and dorsomedial hypothalamic nuclei whose collective dendrites describe a horizontally oriented plexus which encircles the parvocellular nucleus of the hypothalamus bilaterally. In addition, the caudal NTS may project lightly to the AP. The lateral parabrachial nucleus provides a very light input as well. These connections, when considered in the context of the known vagal afferent input and reduced blood‐brain barrier of AP, place this structure in a unique position to receive and modulate ascending interoceptive information and to influence autonomic outflow as well.
Development, Modeling, and Control of a Micro-/Nanopositioning 2-DOF Stick–Slip Device

The studies presented in this paper are motivated by the high performances required in micromanipulation/microassembly tasks. For that, this paper presents the development, the modeling, and the control of a 2-DOF (in linear and angular motion) micropositioning device. Based on the stick-slip motion principle, the device is characterized by unlimited strokes and submicrometric resolutions. First, experiments were carried out to characterize the performances of the micropositioning device in resolution and speed. After that, a state-space model was developed for the substep functioning. Such functioning is interesting for a highly accurate task like nanopositioning. The model is validated experimentally. Finally, a controller was designed and applied to the micropositioning device. The results show good robustness margins and a response time of the closed-loop system.
Blinking Patterns in Soft Contact Lens Wearers Can Be Altered with Training

ABSTRACT The blinking patterns of 15 soft contact lens wearers were recorded with a concealed video camera. Each of 20 consecutive blinks were graded, during slow motion replay of the video, as either complete, incomplete, forced, or twitch. Ten of these subjects were instructed to perform blinking exercises for a period of 2 weeks and the remaining 5 subjects acted as controls. After these exercises all the experimental group displayed an increased frequency of complete blinks, whereas the blinking patterns of the control group remained unchanged. Blinking exercises are likely to alleviate many of the signs and symptoms associated with incomplete blinking amongst contact lens wearers.
Gingival Enlargement Management in Bir Hospital – A Case Series

An increase in size of gingiva is a common clinical condition termed as gingival overgrowth. The definite aetiology is unknown. It is classified on the basis of aetiologic factors and pathologic changes. Both localised and generalised overgrowth are encountered commonly and patients are aesthetically, socially, psychologically and functionally disturbed until they revert back to the original contour. Localised gingival enlargement frequently is inflammatory and can also be associated with systemic diseases/condition (hormonal, nutritional, allergic, nonspecific conditioned) or neoplasic and sometimes false enlargement. DIGO is a well documented side effect with the use of anticonvulsant, immunosuppressant, and calcium channel blockers. Total 3% to 84.5% of subjects taking these drugs seem to have significant enlargement. Localised overgrowth are managed by proper diagnosis followed by controlling inflammation and other causative factors before surgical excision. DIGO is managed by drug replacement and surgical excision if required after nonsurgical treatment. Gingivoplasty of gingival margin is necessary to create self-cleansing and aesthetic architecture. palpable. Erosion of teeth with plaque and calculus deposit was found. IOPAR revealed no abnormal finding. Treatment consisted of smoking cessation counselling and four visits of nonsurgical periodontal therapy. Excisional biopsy of the enlargement sent for histopathological assessment revealed chronic inflammatory lesion with no dysplasia. Histopathology report: Stratified squamous epithelium with mild acanthosis and pseudo-epithelomatous hyperplasia, fibrocollagenous tissue, edematous stroma along with diffuse chronic inflammatory cell infiltrate, lymphocyte and congested blood vessels in stroma.