Miracle-dz/UniFAR-FTUs huggingface dataset:
DESIGN AND EVALUATION OF BUCCAL FILM OF DICLOFENAC SODIUM

Diclofenac Sodium causes gastro-intestinal irritation and ulceration on prolonged use. The buccal delivery of Diclofenac Sodium avoids direct contact to mucosa so it should reduce the possibility of ulceration. The buccal films of Diclofenac Sodium were formulated using mucoadhesive polymers like PVA and HPMC. The films were evaluated for their mechanical strength, folding endurance, drug content uniformity, swelling, in vitro residence time, in vitro release, in vitro bioadhesion and in vivo mucoadhesion. Films were found to have good tensile strength and elasticity. The drug content was found to be uniform. The films prepared with HPMC had satisfactory residence time, good bioadhesive strength and the release of drug was matrix diffusion type. The films prepared with PVA have comparatively less bioadhesion and in vitro residence time. The buccal films prepared with PVA can be used for the fast release of drug and so fast action, whereas HPMC films can be used for the sustained release of the drug.
No impact of physical activity on the period of the circadian pacemaker in humans.

The intrinsic period tau of the circadian pacemaker in humans was investigated by means of forced desynchrony. In this protocol, during 6 scheduled days, the sleep-wake alternation was forced to a period of 20h (i.e., 13.5h for wakefulness and 6.5h for sleep). Light intensity was kept below 10 lux. Three experiments were performed. In experiment 1, 12 subjects were free to spend the available time studying, watching videos, and reading books. In experiment 2, at 2h intervals, 11 subjects spent 6 half-hour sessions per subjective day cycling with minimal effort on a cycle trainer, resulting in an average increase of heart frequency of less than 10 beats per minute. In experiment 3, 11 subjects spent the same intervals of time cycling, but now during 20 minutes per session at an average heart rate of between 140 and 150 beats per minute. Core body temperature was measured continuously. A deconvolution technique discriminated the impact of the circadian pacemaker on body temperature from the impact of activities related to sleeping and waking. From this analysis, the period of the pacemaker was derived. We found the following results: experiment 1, tau = 24.30 +/- 0.36h; experiment 2, tau = 24.17 +/- 0.45h; experiment 3, tau = 23.98 +/- 0.42h. The trend of shorter tau at higher levels of physical activity was not statistically significant. We conclude that tau in humans, determined under conditions of forced desynchrony, is very close to 24h. The suggestion from the literature that single activity pulses would predominantly yield phase delays of the circadian pacemaker is not confirmed by these multiple pulse experiments because no lengthening of tau with increasing effort was observed.
A multi-faces tracking and recognition framework for surveillance system

A novel framework for unsupervised multi-faces tracking and recognition is built on Detection-Tracking-Recognition (DTR) approach. This framework proposed a hybrid face detector for real-time face tracking which is robust to occlusions and posture changes. Faces acquired during unsupervised detection stage will be further processed by SIFT operator in order to cluster face sequence into certain groups. After that, the relevant faces are put together which is of much importance for face recognition in videos. The framework is validated on several videos collected in unconstrained condition (20min each.). The framework can track the face and automatically group a serial faces for a single human-being object in an unlabeled video robustly.
Emotions in motion

This paper outlines some of the challenges and possibilities of a corpus-based approach to the diachronic description of the semantics of emotion words. It analyses three German anger words (Wut, Zorn and Ärger) in two corpora: DTA (Deutsches Textarchiv, covering the period 1600–1899) and DWDS (Digitales Wörterbuch der Deutschen Sprache, which covers twentieth-century German). The study is based on two complementary approaches: a semantic and pragmatic analysis of co-occurrences (Oster, 2012); and the use of semantic foci (Ogarkova & Soriano, 2014). This allows for a detailed description of the semantic evolution of the three anger words for four aspects of emotion – Control, Lack of Control, Visibility and Internalization – while exploring the advantages of a combined quantitative and qualitative corpus analysis.
An adaptive method to determine the number of clusters in clustering process

A difficult problem of most clustering algorithms is how to specify the appropriate number of clusters. This paper proposes an adaptive method of selecting of number of clusters in clustering process by making coefficients indicated the appropriate number of clusters. The intra-cluster coefficient reflects intra distortion of cluster through maximum distance and a mean distance of cluster's extremely marginal objects. The inter-cluster coefficient reflects distance among clusters. It is ratio between closest distance from this cluster's centre to an extremely marginal object of other cluster and mean distance from this cluster's centre to all of extremely marginal object of other cluster respectively. A new coefficient that indicates the appropriate number of clusters is build from the intra-cluster coefficient and inter-cluster coefficient. The looking for extremely marginal objects and the new coefficient are integrated in a weighted FCM algorithm and it is calculated adaptively while the weighted FCM is processing. The weighted FCM algorithm integrated new coefficient is called FCM++. We experiment with FCM++ on some data sets of UCI: Iris, Wine, Soybean-small and show encouraging results.
Source localization and separation using Random Sample Consensus with phase cues

In this paper we present a system for localization and separation of multiple speech sources using phase cues. The novelty of this method is the use of Random Sample Consensus (RANSAC) approach to find consistency of interaural phase differences (IPDs) across the whole frequency range. This approach is inherently free from phase ambiguity problems and enables all phase data to contribute to localization. Another property of RANSAC is its robustness against outliers which enables multiple source localization with phase data contaminated by reverberation noise. Results of RANSAC based localization are fed into a mixture model to generate time-frequency binary masks for separation. System performance is compared against other well known methods and shows similar or improved performance in reverberant conditions.
A model for quality guaranteed resource-aware stream mining

Data streams are produced continuously at a high speed. Most data stream mining techniques address this challenge by using adaptation and approximation techniques. Adapting to available resources has been addressed recently. Although these techniques ensure the continuity of the data mining process under resource limitation, the quality of the output is still an open issue. In this paper, we propose a generic model that guarantees the quality of the output while maintaining efficient resource consumption. The model works on estimating the quality of the output given the available resources. Only a subset of these resources will be used that guarantees the minimum quality loss. The model is generalized for any data stream mining technique.
Interaction of Human Osteoblast-Like Saos-2 and MG-63 Cells with Thermally Oxidized Surfaces of a Titanium-Niobium Alloy

An investigation was made of the adhesion, growth and differentiation of osteoblast-like MG-63 and Saos-2 cells on titanium (Ti) and niobium (Nb) supports and on TiNb alloy with surfaces oxidized at 165°C under hydrothermal conditions and at 600°C in a stream of air. The oxidation mode and the chemical composition of the samples tuned the morphology, topography and distribution of the charge on their surfaces, which enabled us to evaluate the importance of these material characteristics in the interaction of the cells with the sample surface. Numbers of adhered MG-63 and Saos-2 cells correlated with the number of positively-charged (related with the Nb2O5 phase) and negatively-charged sites (related with the TiO2 phase) on the alloy surface. Proliferation of these cells is correlated with the presence of positively-charged (i.e. basic) sites of the Nb2O5 alloy phase, while cell differentiation is correlated with negatively-charged (acidic) sites of the TiO2 alloy phase. The number of charged sites and adhered cells was substantially higher on the alloy sample oxidized at 600°C than on the hydrothermally treated sample at 165°C. The expression values of osteoblast differentiation markers (collagen type I and osteocalcin) were higher for cells grown on the Ti samples than for those grown on the TiNb samples. This was more particularly apparent in the samples treated at 165°C. No considerable immune activation of murine macrophage-like RAW 264.7 cells on the tested samples was found. The secretion of TNF-α by these cells into the cell culture media was much lower than for either cells grown in the presence of bacterial lipopolysaccharide, or untreated control samples. Thus, oxidized Ti and TiNb are both promising materials for bone implantation; TiNb for applications where bone cell proliferation is desirable, and Ti for induction of osteogenic cell differentiation.
Development of A Space Arm-Hand System for On-orbit Servicing

Facing current on-orbit servicing tasks, a space arm-hand system is designed and developed in this paper. Firstly, through contrast and analysis, the arm configuration of non-biased elbow and spherical wrist is identified, and the space hand system adopts the five-fingered dexterous robot hand. Secondly, the 6-DOF space arm system is accomplished including humanoid links and two different types of modular joints highly integrated in mechanical, electrical and control design. For the sake of attractive appearance and safety, the internal alignment design is adopted. Thirdly, the five-fingered space hand system is developed from modular fingers, multi-sensor integration system and hardware system. Finally, the system control strategy is formulated according to different on-orbit servicing stages and the corresponding ground verification test is arranged. The test result confirms on-orbit servicing capability of this space arm-hand system.
The Largest Admitted IT Project Failure in the Southern Hemisphere: A Teaching Case

The Queensland Health implementation project failure is the largest IS failure in the southern hemisphere to date, costing $1.25 billion AUD. This case highlights the importance of systematically analysing project failure. It examines the case organization details, royal commission report, auditor general report and 118 witness statements pertaining to the Queensland Health implementation project. The objective of this teaching case is (1) to illustrate the factors that contributed to Queensland Health’s disastrous implementation project and (2) to understand the broader applications of this project failure on state and national legislations as well as industry sectors. The case narrative and teaching notes are appropriate for both undergraduate and postgraduate students studying IS and project management subjects.
A Vocabulary-Free Infinity-Gram Model for Nonparametric Bayesian Chord Progression Analysis

This paper presents probabilistic n-gram models for symbolic chord sequences. To overcome the fundamental limitations in conventional models—that the model optimality is not guaranteed, that the value of n is fixed uniquely, and that a vocabulary of chord types (e.g., major, minor, ··· )i s defined in an arbitrary way—we propose a vocabulary-free infinity-gram model based on Bayesian nonparametrics. It accepts any combinations of notes as chord types and allows each chord appearing in a sequence to have an unbounded and variable-length context. All possibilities of n are taken into account when calculating the predictive probability of a next chord given a particular context, and when an unseen chord type emerges we can avoid out-of-vocabulary error by adaptively evaluating the 0-gram probability, i.e., the combinatorial probability of note components. Our experiments using Beatles songs showed that the predictive performance of the proposed model is better than that of the state-of-theart models and that we could find stochastically-coherent chord patterns by sorting variable-length n-grams in a line according to their generative probabilities.
A DSGE MODEL OF THE U . S . ECONOMY WITH STOCHASTIC VOLATILITY AND PARAMETER DRIFTING

In this paper the authors report the results of the estimation of a rich dynamic stochastic general equilibrium (DSGE) model of the U.S. economy with both stochastic volatility and parameter drifting in the Taylor rule. They use the results of this estimation to examine the recent monetary history of the United States and to interpret, through this lens, the sources of the rise and fall of the Great Inflation from the late 1960s to the early 1980s and of the Great Moderation of business cycle fluctuations between 1984 and 2007. Their main findings are that, while there is strong evidence of changes in monetary policy during Chairman Paul Volcker’s tenure at the Federal Reserve, those changes contributed little to the Great Moderation. Instead, changes in the volatility of structural shocks account for most of it. Also, although the authors find that monetary policy was different under Volcker, they do not find much evidence of a big difference in monetary policy among the tenures of Chairmen Arthur Burns, G. William Miller, and Alan Greenspan. The difference in aggregate outcomes across these periods is attributed to the time-varying volatility of shocks. The history for inflation is more nuanced, as a more vigorous stand against it would have reduced inflation in the 1970s, but not completely eliminated it. In addition, they find that volatile shocks (especially those related to aggregate demand) were important contributors to the Great Inflation. (JEL E10, E30, C11)
On a class of 4D Kähler bases and AdS5 supersymmetric black holes

We construct a class of toric Kahler manifolds, 4, of real dimension four, a subset of which corresponds to the Kahler bases of all known 5D asymptotically AdS5 supersymmetric black-holes. In a certain limit, these Kahler spaces take the form of cones over Sasaki spaces, which, in turn, are fibrations over toric manifolds of real dimension two. The metric on 4 is completely determined by a single function H(x), which is the conformal factor of the two dimensional space. We study the solutions of minimal five dimensional gauged supergravity having this class of Kahler spaces as base and show that in order to generate a five dimensional solution H(x) must obey a simple sixth order differential equation. We discuss the solutions in detail, which include all known asymptotically AdS5 black holes as well as other spacetimes with non-compact horizons. Moreover we find an infinite number of supersymmetric deformations of these spacetimes with less spatial isometries than the base space. These deformations vanish at the horizon, but become relevant asymptotically.
Directional vs non-directional modes of vibrotactile feedback for arm posture replication

This paper presents an integrated system for upper limb rehabilitation which uses small inertia-based sensors and vibrotactile feedback devices. Vibrotactile feedback is incorporated together with two Inertial Measurement Units (IMUs) attached at the upper arm and the forearm to measure arm motions. The whole arm posture is modeled using three parameters - wrist position, elbow position, and forearm's orientation. Two different strategies of utilizing vibrotactile feedback for arm posture replication are discussed in this paper. The vibrotactile feedback is used firstly as a directional indicator and secondly as a non-directional indicator that informs the user of matching errors between the current posture and the target posture. The experiments involve seven student volunteers replicating five different arm postures. Results show that the non-directional vibrotactile feedback enables faster and more accurate arm posture correction.
Knowledge Management Cultures: A Comparison of Engineering and Cultural Science Projects

This work in progress presents an approach to compare patterns of communication and knowledge organization in cultural and engineering science projects under the leading point of media use. The goal of the underlying project is to gain a better understanding on similarities and di erences in both areas and to develop more appropriate information system support for both areas. Central to the comparative analysis approach is a process knowledge repository which was successfully used in two case studies about real world information systems.
An Application with Non-identical Parallel Machines using Genetic Algorithm with the Help of Fuzzy Logic

After industrial revolution in Europe, manufacturing systems have become very important research areas. In shifting and improving world, manufacturing is a positive function of consumption of humankind. In this regard, there has been too many algorithms and methodologies about scheduling to find a solution to combinatorial complex problems. In the literature, most of the articles about production scheduling are related with identical parallel machines. Even though it is a common problem in the industry, only a small number of studies deal with non-identical parallel machines. This paper is about fuzzy approach to scheduling problem of non-identical parallel machines using genetic algorithm. The genetic algorithm is proposed here fits the nonidentical parallel machine scheduling problem of minimizing the maximum completion time.
Angiotensin-(1–7) activates a tyrosine phosphatase and inhibits glucose-induced signalling in proximal tubular cells

Background. In the diabetic kidney, stimulation of mitogen-activated protein kinases (MAPKs) leads to extracellular matrix protein synthesis. In the proximal tubule, angiotensin-(1–7) [Ang-(1–7)] blocks activation of MAPKs by angiotensin II. We studied the effect of Ang-(1–7) on signalling responses in LLC-PK1 cells in normal (5 mM) or high (25 mM) glucose. Methods. The p38 MAPK was assayed by immunoblot, Src homology 2-containing protein-tyrosine phosphatase-1 (SHP-1) activity was measured after immunoprecipitation, cell protein synthesis was determined by [3H]-leucine incorporation and transforming growth factor-β1 (TGF-β1), fibronectin and collagen IV were assayed by immunoblots and/or ELISA. Results. High glucose stimulated p38 MAPK. This response was inhibited by Ang-(1–7) in a concentration-dependent fashion, an effect reversed by the receptor Mas antagonist A-779. Ang-(1–7) increased SHP-1 activity, via the receptor Mas. An inhibitor of tyrosine phosphatase, phenylarsine oxide, reversed the inhibitory effect of Ang-(1–7) on high glucose-stimulated p38 MAPK. Ang-(1–7) inhibited high glucose-stimulated protein synthesis, and blocked the stimulatory effect of glucose on TGF-β1. Conversely, Ang-(1–7) had no effect on glucose-stimulated synthesis of fibronectin or collagen IV. Conclusions. These data indicate that in proximal tubular cells, binding of Ang-(1–7) to the receptor Mas stimulates SHP-1, associated with the inhibition of glucose-stimulated p38 MAPK. Ang-(1–7) selectively inhibits glucose-stimulated protein synthesis and TGF-β1. In diabetic nephropathy, Ang-(1–7) may partly counteract the profibrotic effects of high glucose.
Using Electroencephalogram (EEG) to Understand The Effect of Price Perception on Consumer Preference

The research examines the influence of price as product cues on consumer’s perception and evaluation by using the application of electroencephalogram (EEG). This method can give objective information about consumer reactions towards product cues that will drive consumer’s choice. The main research objective was to observe and evaluate consumer’s brain activity in different brain regions while they were being exposed by several price levels (low, medium, high) of underwear as stimuli and focused mainly on liking/disliking the stimuli. The participants consist of 10 female and 10 male consumers within 18-24 years old, have normal vision, right handed, and considered as potential purchasers of underwear. The participant’s brain activity was collected using Emotiv EPOC neuroheadset (EEG) with international 10/20 system and was obtained in Beta frequency bands (13–30 Hz). The result indicated that there was a clear and significant change (p<0.05) in the EEG brain spectral activities of right and left hemisphere in the frontal (F3 & F4), temporal (T7 & T8), and parietal (P7 & P8) regions when participants indicated their attentiveness towards each price level stimulus. The results show, the male and female participant’s tactile sensations in parietal lobe does not give more favorable attention towards particular price stimulus, but the difference price perceptions in parietal lobe can lead to rational preference and give most favored response towards high price stimulus. Analyzing of price perception may help to understand the differences in price-related emotions and preference, which can gain insights into an alternative pricing strategy that can lead to influence consumers buying decision.
Determination of Protein Functional Groups Using the Bond Energy Algorithm

Nowadays it is possible to understand the basic components and organization of cell machinery from the network level due to increased availability of large-scale protein-protein interaction (PPI) data. Many studies have shown that clustering of the protein interaction network (PIN) can be found as an effective approach for identifying protein complexes or functional modules. A significant number of proteins in such PIN remain uncharacterized and predicting their function remains a major challenge in system biology. We propose a protein annotation method based on clustering according to Bond Energy Algorithm (BEA), which first transforms the PIN into matrix form suitable for BEA, and after generating the resulting matrix of the BEA the AUTOCLASS algorithm is performed to obtain the PIN clusters. Protein functions are assigned based on cluster information. Experiments were performed on PPI data from the bakers’ yeast and since the network is noisy and still incomplete, we use pre-processing and purifying. Results reveal improvement over previous techniques and the most prominent characteristic of the BEA clustering is that the clustering result is not dependent of the initial number of clusters.
A Location-Based Peer-to-Peer Network for Context-Aware Services in a Ubiquitous Environment

With the popularization of today’s mobile devices, the environment that enables us to publish and utilize information independent of location and time has been actualized. In the future, various kinds of sensors such as GPS as well as network-enabled appliances will also be connected to the Internet. By utilizing various kinds of information acquired from these network terminals, advanced context-aware services will be produced. For realizing context-aware services, we focus on information management and retrieval using a Peer-to-Peer (P2P) network. In this paper, we propose a location-based P2P network named the LL-Net. By constructing a P2P overlay network based on locations of peers, the LL-Net achieves efficient propagation of location-dependent queries issued by context-aware services.