Miracle-dz/UniFAR-FTUs huggingface dataset:
Improving risk communication: a proof-of-concept randomised control trial assessing the impact of visual aids for neurosurgical consent

Introduction Informed consent is a fundamental component in the work-up for surgical procedures. Statistical risk information pertaining to a procedure is by nature probabilistic and challenging to communicate, especially to those with poor numerical literacy. Visual aids and audio/video tools have previously been shown to improve patients' understanding of statistical information. In this study, we aimed to explore the impact of different methods of risk communication in healthy participants randomized to either undergo the consent process with visual aids or the standard consent process for lumbar puncture. Material and methods Healthy individuals above 18 years old were eligible. The exclusion criteria were prior experience of the procedure or relevant medical knowledge, lack of capacity to consent, underlying cognitive impairment and hospitalised individuals. After randomisation, both groups received identical medical information about the procedure of a lumbar puncture in a hypothetical clinical scenario via different means of consent. The control group underwent the standard consent process in current clinical practice (Consent Form 1 without any illustrative examples), whereas the intervention group received additional anatomy diagrams, the Paling Palette and the Paling perspective scale. Anonymised questionnaires were received to evaluate their perception of the procedure and its associated risks. Results Fifty-two individuals were eligible without statistically significant differences in age, sex, professional status and the familiarity of the procedure. Visual aids were noted to improve the confidence of participants to describe the risks by themselves (p = 0.009) and participants in the intervention group felt significantly less overwhelmed with medical information (p = 0.028). The enhanced consent process was found to be significantly more acceptable by participants (p = 0.03). There was a trend towards greater appropriateness (p = 0.06) and it appeared to have “good” usability (median SUS = 76.4), although this also did not reach statistical significance (p = 0.06) Conclusion Visual aids could be an appropriate alternative method for medical consent without being inferior regarding the understanding of the procedure, its risks and its benefits. Future studies could possibly compare or incorporate multiple interventions to determine the most effective tools in a larger scale of population including patients as well as healthy individuals.
Evolutionary Events Promoted Polymerase Activity of H13N8 Avian Influenza Virus

Wild birds are considered to be the natural reservoir hosts of avian influenza viruses (AIVs). Wild bird-origin AIVs may spill over into new hosts and overcome species barriers after evolutionary adaptation. H13N8 AIVs used to be considered primarily circulated in multispecies gulls but have recently been shown to possess cross-species infectivity. In this study, we analyzed the genetic changes that occurred in the process of the evolution of H13 AIVs. Phylogenetic analysis revealed that H13 AIVs underwent complex reassortment events. Based on the full genomic diversity, we divided H13 AIVs into 81 genotypes. Reassortment experiments indicated that basic polymerase 2 (PB2) and nucleoprotein (NP) genes of the H9N2 AIV significantly enhanced the polymerase activity of the H13N8 AIV. Using the replication-incompetent virus screening system, we identified two mutations, PB2-I76T and PB2-I559T, which could enhance the polymerase activity of the H13N8 AIV in mammalian cells. Notably, these mutations had been acquired by circulating H13N8 AIVs in 2015. These findings suggest that H13N8 AIVs are about to cross the host barrier. Occasional genetic reassortments with other AIVs and natural mutation events could promote this process. It is imperative to intensify monitoring efforts for H13N8 AIVs.
Internal Pressure Pattern Design for Variable Surface Shapes of Tongue-Type Pneumatic Soft Actuator

Pneumatic soft actuators with arrayed chambers (PSAC) can reproduce complex and various shapes such as tongues. This study presents a design method for an internal pressure pattern for the tongue-type PSAC. Specifically, using an analytical model, the propose method determines the internal pressure patterns to reproduce the target surface shapes given to PSAC. First, a discrete model representing the surface shape of PSAC for the internal pressure patterns of chambers is constructed using multiple linear elastic elements. Next, the internal pressure patterns to realize the target surface shapes are obtained by nonlinear mathematical optimization using the constructed PSAC surface shape model. Finally, the proposed method is used to obtain the internal pressure patterns for four different target surface shapes. Furthermore, the proposed method is validated through experiments on the actual PSAC.
Genetic variation of FcγRIIa induces higher uptake of Leishmania infantum and modulates cytokine production by adherent mononuclear cells in vitro

Introduction Single nucleotide variations (SNVs) are specific genetic variations that commonly occur in a population and often do not manifest phenotypically. However, depending on their location and the type of nucleotide exchanged, an SNV can alter or inhibit the function of the gene in which it occurs. Immunoglobulin G (IgG) receptor genes have exhibited several polymorphisms, including rs1801274, which is found in the FcgRIIa gene. The replacement of A with T results in a Histidine (H) to Arginine (R) substitution, altering the affinity of the IgG receptor for IgG subtypes and C-reactive protein (CRP). In this study, we analyzed rs1801274 and its functional implications concerning L. Infantum uptake and cytokine production. Methods We genotyped 201 individuals from an endemic area for visceral leishmaniasis to assess the presence of rs1801274 using Taqman probes for a candidate gene study. Additionally, we included seventy individuals from a non-endemic area for a functional study. Subsequently, we isolated and cultivated one-week adherent mononuclear cells (AMCs) derived from the peripheral blood of participants residing in the non-endemic region in the presence of L. infantum promastigotes, with and without antigen-specific IgG and/or CRP. We analyzed the rate of phagocytosis and the production of nitric oxide (NO), tumor necrosis factor (TNF)-a, interleukin (IL)-10, IL-12 p70, IL-1b, IL- 6, and IL-8 in the culture supernatants. Results and discussion In participants from the endemic region, the A/G (H/R isoform) heterozygous genotype was significantly associated with susceptibility to the disease. Furthermore, SNVs induced a change in the phagocytosis rate in an opsonin-dependent manner. Opsonization with IgG increased the production of IL-10, TNF-a, and IL-6 in AMCs with the H/R isoform, followed by a decrease in NO production. The results presented here suggest that the rs1801274 polymorphism is linked to a higher susceptibility to visceral leishmaniasis.
Facile Preparation of β-Cyclodextrin-Modified Polysulfone Membrane for Low-Density Lipoprotein Adsorption via Dopamine Self-Assembly and Schiff Base Reaction

A facile method for the immobilization of β-cyclodextrin on polysulfone membranes with the aim of selectively adsorbing low-density lipoprotein (LDL) was established, which is based on the self-assembly of dopamine on the membrane followed by the Schiff base reaction with mono-(6-ethanediamine-6-deoxy)-β-cyclodextrin. The surface modification processes were validated using X-ray photoelectron spectroscopy and attenuated total reflectance Fourier-transform infrared spectroscopy. Surface wettability and surface charge of the membranes were investigated through the water contact angle and zeta potential analysis. The cyclodextrin-modified polysulfone membrane (PSF-CD) showed good resistance to protein solutions, as shown by the measurement of BSA adsorption. The assessment of BSA adsorption revealed that the cyclodextrin-modified polysulfone membrane (PSF-CD) exhibited excellent resistance to protein solutions. To investigate the adsorption and desorption behaviors of the membranes in single-protein or binary-protein solutions, an enzyme-linked immunosorbent assay was employed. The results revealed that the PSF-CD possessed remarkable adsorption capacity and higher affinity for LDL in both single-protein and binary-protein solutions, rendering it a suitable material for LDL apheresis.
Navigating the Future: A Comprehensive Review of Artificial Intelligence Applications in Gastrointestinal Cancer

This comprehensive review explores the transformative role of artificial intelligence (AI) in the realm of gastrointestinal cancer. Gastrointestinal cancers present unique challenges, necessitating precise diagnostic tools and personalized treatment strategies. Leveraging AI, particularly machine learning and deep learning algorithms, has demonstrated remarkable potential in revolutionizing early detection, treatment planning, prognosis, and drug development. The analysis of current research and technological advancements underscores the capacity of AI to unravel intricate patterns within extensive datasets, providing actionable insights that enhance diagnostic accuracy and treatment efficacy. The transformative impact of AI on the landscape of gastrointestinal cancer is emphasized, signaling a paradigm shift towards more precise and targeted cancer care. The conclusion emphasizes the need for sustained research efforts and collaborative initiatives among AI researchers, healthcare professionals, and policymakers. By fostering interdisciplinary collaboration, we can navigate the evolving field of gastrointestinal cancer care, embracing the potential of AI to improve patient outcomes and contribute to a more effective and personalized approach to cancer management.
Self-reported political ideology

American politics scholarship has relied extensively on self-reported measures of ideology. We evaluate these widely used measures through an original national survey. Descriptively, we show that Americans’ understandings of “liberal” and “conservative” are weakly aligned with conventional definitions of these terms and that such understandings are heterogeneous across social groups, casting doubt on the construct validity and measurement equivalence of ideological self-placements. Experimentally, we randomly assign one of three measures of ideology to each respondent: (1) the standard ANES question, (2) a version that adds definitions of “liberal” and “conservative,” and (3) a version that keeps these definitions but removes ideological labels from the question. We find that the third measure, which helps to isolate symbolic ideology from operational ideology, shifts self-reported ideology in important ways: Democrats become more conservative, and Republicans more liberal. These findings offer first-cut experimental evidence on the limitations of self-reported ideology as a measure of operational ideology, and contribute to ongoing debates about the use of ideological self-placements in American politics.
Multiview Stereo via Noise Suppression PatchMatch

In this article, we reveal and rectify two underlying factors that hinder the performance of previous PatchMatch-based multiview stereo (MVS) methods in texture-less regions. First, previous methods approximate the desire pixel-wise similarity measurement with the patch-wise counterpart, which tends to be misled by ambiguous matches in texture-less areas. Therefore, we propose a novel similarity measurement that takes into account the relation between neighboring pixels and the central one. Second, the projection formula adopted by previous methods mistakes invisible points behind the optical center as visible, which leads to wrong results in view selection and depth maps. We not only rectify the formula, but also propose a geometric restriction that eliminates wrong results by shrinking the solution space of the hypothetical normal vector. These two improved aspects are necessary components of the traditional MVS pipeline and can therefore be easily applied to other PatchMatch-based MVS methods. Experiment results show that the proposed approach can effectively suppress the noise in depth maps while preserving fine details. In terms of ${F} _{\textbf {1}}$ -score, it achieves state-of-the-art performance on ETH3D high-resolution MVS benchmark.
LIVED EXPERIENCES OF STUDENTS DURING THE TRANSITION FROM MODULAR TO IN-PERSON CLASS: ORAL RECITATION IN FOCUS

This phenomenological study aimed to investigate the experiences of senior high school students transitioning from modular to in-person learning in the new normal education setting. The research involved in-depth interviews and focus group discussions with Grade 12 students who had previously used modular learning. Participants, aged 18 or above, were purposively sampled from the Schools Division of City of Mati, having engaged in modular education during the academic years 2020–2021 and 2021–2022. Thematic analysis revealed five major themes related to the students experiences in transitioning, focusing on oral recitation. Another set of four major themes emerged regarding coping mechanisms, and additional themes depicted insights into learning approaches and classroom participation. The study recommends integrating more platforms associated with Speech Mastery Workshops to allow students to practice oral recitation in a supportive environment. Additionally, it advocates for teacher training to enhance educators understanding of emotions, active listening, and empathetic responses. KEYWORDS: senior high school students, oral recitation, transition, in-person class qualitative research, phenomenological approach, thematic analysis, City of Mati
A Lightweight Interlayer Multiscale Dense Network for Classifying Hyperspectral Remote Sensing Images

Multiscale Dense Network (MSDN) is a deep convolutional neural network method proposed to solve the loss of fine features in hyperspectral remote sensing images. Multiscale Dense Network (MSDN), which makes full use of the different scale information in the network, implements feature extraction of HSI in both horizontal and vertical dimensions. Since MSDN maintains all fine scales until the last layer of the network, the computational effort is large. To address this problem, this paper proposes a lightweight Inter layer Short Multiscale Dense Network (IMSDN) method for hyperspectral image classification. HSI classification is performed using network reduction and inert computation to avoid unnecessary computation, the MSDN network is divided into S blocks along the horizontal dimension, keeping the coarsest (S-i+1) scale only in the ith block and only down sampling the final output of each block in the Short Multiscale Dense Network (SMSDN) for HSI classification. On the basis of the SMSDN network, in order to maintain the classification accuracy of the network, the Lightweight Interlayer Multiscale Dense Network (IMSDN) utilizes three scales of convolution kernels in different horizontal directions to extract the image features separately, which are then fused for the classification of HSI. Experiments are conducted on two publicly available datasets and the results are compared with other methods to demonstrate that the IMSDN network has less computation and shortens the experiment time compared to the MSDN network while guaranteeing the classification accuracy.
ECOLOGY OF GRACILARIA TIKVAHIAE MCLACHLAN (GIGARTINALES, RHODOPHYTA) IN THE GREAT BAY ESTUARY, NEW HAMPSHIRE

The reproductive phenology, growth and variation of chemical composition of Gracilaria tikvahiae from the Great Bay Estuary, N.H. were evaluated. A major objective was an analysis of the chemical composition, particularly agar content and properties, of plants separated into reproductive categories. The net photosynthetic responses of G. tikvahiae to several irradiance, temperature and salinity regimes were determined. Gracilaria tikvahiae plants from the Great Bay Estuary were vegetative throughout most of the year. However, discrete maxima of tetrasporic and spermatangial plants occurred during June-July and for cystocarpic plants during July-August. The in situ growth of Gracilaria tikvahiae was highest during June-September, with maximum rates of 11%/day. The growth cycle of G. tikvahiae plants was most strongly correlated with water temperature. Seasonal variations of surface irradiance and dissolved inorganic nitrogen were not related to the growth cycle of G. tikvahiae. Gracilaria tikvahiae had annual cycles of ash, dry weight, carbohydrate, agar, carbon, nitrogen and phycoerythrin contents. In contrast, little variation in protein, phosphorus or chlorophyll occurred. The changes in tissue carbon, nitrogen, carbohydrate and agar had summer minima and winter maxima. However, the ash content was maximal in summer and lowest during winter. The total tissue nitrogen of G. tikvahiae did not decrease below 2% of dry weight. No significant differences in chemical composition were noted between reproductive stages. The agar content of Gracilaria tikvahiae varied between 7% (summer) and 23% (winter). The gel strengths and 3,6-anhydrogalactose content of G. tikvahiae agar were highest in the summer. There were no significant differences in 3,6-anhydrogalactose, sulfate, ash content, gel strength or viscosity between agar, extracted with hydroxide pretreatment, from cystocarpic or tetrasporic plants. The net photosynthesis of Gracilaria tikvahiae was light-saturated at 200-600 (mu)E(.)m('-2)(.)s('-1), but it was not inhibited at 1440 (mu)E(.)m('-2)(.)s('-1). G. tikvahiae had increasing net photosynthetic rates from 5(DEGREES) to 25(DEGREES)C. Maximum net photosynthesis occurred between 25(DEGREES) and 35(DEGREES)C, while rates decreased at 37.5(DEGREES)C. The net photosynthetic responses at 25(DEGREES) and 30(DEGREES)C were stable after acclimation times of one to four days, but declined after three days at 35(DEGREES)C. G. tikvahiae has a euryhaline net photosynthetic response between 5 g/ kg and 40 g/kg.
The relationships between work-family conflict and life satisfaction and happiness among nurses: a moderated mediation model of gratitude and self-compassion

Background Researchers and practitioners are concerned with the impact of work-family conflict on the well-being of workers, including those in the health care sector, and previous research suggested that nurses were experiencing a range of negative outcomes. Aim To investigate the potentially mediating role of self-compassion and moderating role of gratitude in the relationships between work-family conflict and both life satisfaction and happiness among Saudi nurses. Method A cross-sectional survey was conducted with 368 nurses (men age = 35.18, SD = 6.67, 70.65% of females). Nurses were recruited via social media using convenience sampling techniques. They completed the Satisfaction with Life Scale, the Subjective Happiness Scale, the Gratitude Questionnaire–6, the Self-Compassion Scale, and the Work-Family Conflict Scale, as well as a set of demographic questions. The data were analyzed using PROCESS MACRO model 4 and 8, and the reporting followed STROBE checklist. Results As expected, the study found a negative relationship between work-family conflict and both life satisfaction and happiness. These relationships were mediated by self-compassion. For the relationships between work-family conflict and life satisfaction and happiness, and between family-work conflict and happiness, this mediation was moderated by gratitude. Conclusion This study built on positive psychology and demonstrated that the positive personality traits of self-compassion and gratitude can engender enhanced life satisfaction and happiness among Saudi nurses.
Evaluasi Pengolahan Air Limbah Domestik dengan IPAL Komunal di Kota Bogor

ABSTRACTOne of domestic wastewater treatment in Bogor City is by using communal WWTP (Wastewater Treatment Plant) system. The communal WWTP treats domestic wastewater with an anaerobic baffled reactor configuration (ABR). This study aims to determine the effluent quality of communal WWTP so that it can be used as reference for related institutions in managing communal WWTP. The effluent from 3 communal WWTPs namely KSM Amanah, Rosella, and Cipendek Indah measured the content of TSS, COD, oil and grease, ammonia, and total coliform. The secondary data of effluent from 40 communal WWTP were obtained from Environment Agency of Bogor City. The result of the effluent analysis is compared with the Minister of Environment and Forestry Regulation No. P.68/2016 on the Quality Standard of Domestic Wastewater. The study showed that the total coliform parameter did not meet the quality standard in 3 communal WWTP locations, COD exceeded the quality standard in KSM Rosella and Cipendek Indah, and TSS above the quality standard in KSM Cipendek Indah. The communal WWTP in Bogor city has not been effective in reducing the pollutant content in domestic wastewater especially BOD and total coliform. The communal WWTP management needs to be improved in order for better effluent.Keywords: domestic waste, communal WWTP, effluent, quality standard, bogor cityABSTRAKSalah satu pengolahan air limbah domestik di Kota Bogor yaitu menggunakan sistem IPAL komunal. IPAL komunal mengolah air limbah domestik dengan konfigurasi anaerobic baffled reactor (ABR). Penelitian ini bertujuan untuk mengetahui kualitas efluen IPAL komunal di Kota Bogor sehingga dapat dijadikan acuan bagi instansi terkait dalam mengelola IPAL komunal. Efluen dari 3 IPAL komunal yaitu KSM Amanah, Rosella, dan Cipendek Indah diukur kandungan TSS, COD, minyak lemak, amonia, dan total coliform. Data sekunder efluen dari 40 IPAL komunal diperoleh dari Dinas Lingkungan Hidup Kota Bogor. Hasil analisis efluen tersebut dibandingkan dengan baku mutu PermenLHK No. P.68/2016 tentang Baku Mutu Air Limbah Domestik. Penelitian menunjukkan bahwa parameter total coliform tidak memenuhi baku mutu di 3 lokasi IPAL komunal yang diteliti, COD melebihi baku mutu di KSM Rosella dan Cipendek Indah, serta TSS diatas baku mutu teridentifikasi di KSM Cipendek Indah. IPAL komunal di Kota Bogor belum efektif dalam menurunkan kandungan polutan dalam air limbah domestik terutama BOD dan total coliform. Pengelolaan IPAL komunal perlu ditingkatkan agar kualitas efluen yang dihasilkan lebih baik. Kata kunci: limbah domestik, IPAL komunal, efluen, baku mutu, kota bogor
A First Omics Data Integration Approach in Hass Avocados to Evaluate Rootstock–Scion Interactions: From Aerial and Root Plant Growth to Fruit Development

Grafting, the careful selection of rootstocks and scions, has played a crucial role maintaining Chilean avocado fruit quality standards in a scenario in which climate change and drought-related issues have considerably decreased avocado fruit production in the last fifteen years. The historical use of seedling rootstocks in Chile has experienced a recent shift towards clonal rootstocks, driven by the potential to produce more consistent and predictable crops. This research aims to compare Hass avocado plants grafted on Mexicola seedling and Dusa® clonal rootstocks in a soilless and protected system using (i) a differential expression analysis of root and leaf samples and (ii) a fruit transcriptomic and metabolomic integration analysis to improve our understanding of rootstock–scion interaction and its impact on avocado tree performance and fruit quality. The results demonstrated that no significant transcriptomic and metabolomic differences were identified at fruit level in the ready-to-eat (RTE) stage for Hass avocado fruit from both rootstocks. However, Hass avocados grafted on the clonal rootstock showed greater aerial growth and slightly increased fruit size than the seedling rootstock due to the enrichment of cell wall-remodeling genes as revealed in leaves and fruit at harvest stage.