Miracle-dz/UniFAR-FTUs huggingface dataset:
Effect of the coupled administration of Lydium-KLP or methisoprinol and respisure on the health status and prevention of mycoplasmal pneumonia of swine in large-scale commercial breeding

The study was aimed on determining the clinical protective value of Lydium-KLP and Methisoprinol in the prevention of respiratory system diseases, as well as their effect on the health status of pigs in large-scale commercial breeding and on the improvement of in the effectiveness of specific immunoprophylaxis of mycoplasmal pneumonia of in swine (MPS). Piglets at the age of 7 d were divided into eight groups of 25-30 piglets each. On days 7 and 21 of life they were immunised with Respisure vaccine (group I) or administrated Lydium-KLP or Methisoprinol (groups IV and VII). In other groups, Lydium-KLP or Methisoprinol were given simultaneously (groups II and V) or 48 h before immunisation with Respisure (groups III and VI). Control piglets were administrated PBS (group C). Clinical observations as well as post-slaughter and animal husbandry analyses indicated that the simultaneous administration of Lydium-KLP or Methisoprinol with Respisure gives better results in comparison to immunisationonly with Respisure. The statistically-significant differences were found in the mean percentage of meatiness between groups receiving Methisoprinol with or 48 h before Respisure and control group, as well as in the point evaluation of lesions in the lungs between groups receiving Lydium-KLP with Respisure and Methisoprinol 48 h before Respisure and control group. The study demonstrated the beneficial effect of coupled administration of Lydium-KLP or Methisoprinol and Respisure on the improvement of health status and the productive performance of pigs, as well as on the effectiveness of specific immunoprophylaxis of MPS in large– scale commercial breeding. The most beneficial variants of coupled administration were the simultaneous application of LydiumKLP and Respisure, and Methisoprinol application 48 h before immunisation with Respisure.
Towards a generic framework for empirical studies of Model-Driven Engineering

The goal of this paper is to introduce a work-in-progress approach that intends to formalize and facilitate empirical studies in Software Engineering in general and in Model-Driven Engineering in particular. The main idea is to use a detailed model of software that makes explicit the different intermediate models used at the different levels of abstraction, their different quality characteristics together with their relationships. The expected benefits of using such an explicit modeling is illustrated though five examples for which empirical studies are designed (but not yet conducted) on basis of that approach.
ON A CONJECTURE OF CONRAD, DIAMOND, AND TAYLOR

We prove a conjecture of Conrad, Diamond, and Taylor on the size of certain deformation rings parametrizing potentially Barsotti-Tate Ga- lois representations. To achieve this, we extend results of Breuil and M ezard (classifying Galois lattices in semistable representations in terms of \strongly divisible modules") to the potentially crystalline case in Hodge-Tate weights (0; 1). We then use these strongly divisible modules to compute the desired deformation rings. As a corollary, we obtain new results on the modularity of potentially Barsotti-Tate representations.
Opór indywidualny. Teorie, klasyfikacje i diagnozowanie w ujęciu psychologicznym

W artykule zaprezentowano rekonstrukcję psychologicznych ujęć zagadnienia indywidualnego oporu. Wśród nich znalazły się stanowiska definiujące opór jako dyspozycję, stan motywacyjny, stan mentalny lub typ relacji. Uwzględniono również ujęcie oporu w kontekście konfrontacji z autorytetem oraz w perspektywie teorii perswazji. W efekcie pozwoliło to na sformułowanie propozycji wspólnego mianownika różnych stanowisk oraz uwypuklenie możliwości empirycznego ujęcia zjawiska indywidualnego oporu. W tym kontekście zaprezentowane zostały również teoretyczne podstawy oraz psychometryczne właściwości kluczowych narzędzi pomiaru indywidualnego oporu.
Seedling recruitment in a hurricane‐driven tropical forest: light limitation, density‐dependence and the spatial distribution of parent trees

1 We used inverse modelling to parameterize spatially‐explicit seedling recruitment functions for nine canopy tree species in the Luquillo Forest Dynamics Plot (LFDP), Puerto Rico. We modelled the observed spatial variation in seedling recruitment following Hurricane Georges as a function of the potential number of seedlings at a given location (based on local source trees and the potential contribution of parents from outside of the mapped area) and of light levels and density‐dependent mortality during establishment. We adopted the model comparison paradigm and compared the performance of increasingly complex models against a null model that assumes uniform seedling distribution across the plot. 2 Our data supported a model in which parents must reach a threshold size before any seedling production will occur. Once parents attain that size, the relationship between tree diameter and the number of seedlings produced is fairly flat for the majority of species. These results contradict previous analyses that simply assumed a linear relationship between biomass and seedling production and a uniform size threshold for seedling production across species. 3 The majority of species tested supported models that included at least one of a bath term (contribution from non‐local trees), conspecific density dependence and light availability after the hurricane. Density dependence shifted the mode of the effective dispersal kernel away from potential parent trees and significantly reduced the number of seedlings established near parent trees. Recruitment from non‐local sources accounted for 6–81% of observed seedling recruitment depending upon the tree species. Light availability appeared to divide species into three groups that showed more successful seedling establishment at low (< 5% of full sun), intermediate or high light levels (> 30% full sun). 4 Differences between individual species in the importance of local vs. bath recruitment and the intensity of density dependence suggest the existence of distinct recruitment syndromes that go beyond the traditional focus of tropical tree life histories. Understanding these syndromes will provide valuable insights into the spatial distribution of tropical tree species and the maintenance of tropical forest diversity.
Closed versus open system models and their impact on performance

Workload generators may be classified as based on a closed system model, where new job arrivals are only triggered by job completions (followed by think time), or an open system model, where new jobs arrive independently of job completions. In general, system designers pay little attention to whether a workload generator is closed or open. Using a combination of implementation and simulation experiments, we illustrate that there is a vast difference in behavior between open and closed models in realworld settings. We synthesize these differences into eight simple guiding principles, which serve three purposes. First, the principles specify how scheduling policies are impacted by closed and open models, and explain the differences in user level performance. Second, the principles motivate the use of partly open system models, whose behavior we show to lie between that of closed and open models. Finally, the principles provide guidelines to system designers for determining which system model is most appropriate for a given workload.
Optical Trapping of Nanoparticles and Quantum Dots

Optical manipulation of nanostructures offers new exciting possibilities for building new nano-architectures and for exploring the fundamental interactions between light and nanoparticles. The optical properties of nanostructures differ substantially from those of similar bulk material and exhibit an exquisite sensitivity on nanoparticle shape and composition. The plethora of particles available today expands the possibilities of optical manipulation to include control over particle temperature, luminescence, orientation, and even over the rotational optical momentum transferred to the nanoparticle. Here, we summarize recent experimental advances within optical manipulation of individual nanoparticles and quantum dots with a focus on resonant versus non-resonant trapping, optically induced heating, spherical aberration, and orientation control. Also, we present novel quantitative data on the photonic interaction between gold nanoshells and a focused laser beam. Lastly, promising applications of the biophotonical properties of nanoparticles within nanoscience and biophysics are pointed out.
Glycans on Secretory Component Participate in Innate Protection against Mucosal Pathogens*

In mucosal secretions, secretory component (SC) is found either free or bound to polymeric IgA within the secretory IgA complex. SC displays numerous and various glycans, which are potential ligands for bacterial compounds. We first established that human SC (hSC) purified from colostrum (hSCcol) or produced in Chinese hamster ovary cells (hSCrec) exhibits the same lectin reactivity. Both forms bind to Clostridium difficile toxin A and functionally protect polarized Caco-2 cell monolayers from the cytopathic effect of the toxin. The interaction is mediated by glycans present on hSC and involves galactose and sialic acid residues. hSCcol and hSCrec were also shown to bind enteropathogenic Escherichia coli adhesin intimin and to inhibit its infectivity on HEp-2 cells in a glycan-dependent manner as well. SC remained operative in the context of the whole secretory IgA molecule and can therefore enhance its Fab-mediated neutralizing properties. On the contrary, hSC did not interact with three different strains of rotavirus (RF, RRV, and SA11). Accordingly, infection of target MA104 cells with these rotavirus strains was not reduced in the presence of either form of hSC tested. Although not a universal mechanism, these findings identify hSC as a microbial scavenger contributing to the antipathogenic arsenal that protects the body epithelial surfaces.
The triplex theory of vision: the fourth dimension

In 1993, based on my original 1981 research on serial sections of human embryos, I proposed that vision may have three components, rather than just 2—the rods and cones. I termed the third component nonvisual retinal ganglion cells (NVRGCs)(ipRGCs: intrinsically photosensitive retinal ganglion cells NVRGCs: nonvisual retinal ganglion cells, PACAP: pituitary adenylate cyclase-activating polypeptide RHT: retinohypothalamic tract); subsequent researchers identified the same phenomenon, but used a different term, intrinsically photosensitive retinal ganglion cells (ipRGCs). I also reported nonvisual photopigments, one of which, with more recent techniques, has been identified as melanopsin. The purpose of this paper is to synthesize my earlier research with more recent findings to establish the triplex theory of vision and to describe the fourth, nonvisual , dimension of vision and its possible future applications for affecting circadian rhythm, pupillary light reaction, hormonal activities, mood changes, thermal regulation, sleep, and other nonvisual functions.
Racial discrimination, ethnicity and work stress.

BACKGROUND Previous research has suggested higher work stress among minority ethnic workers. AIMS To determine levels of work stress in three ethnic groups, consider the contribution of racial discrimination to the groups' profiles of occupational and demographic associations with stress, and assess the association between work stress and well-being. METHODS A household quota sample design was used, and 204 black African-Caribbean, 206 Bangladeshi and 216 white (UK born) working people took part in structured interviews. RESULTS More black African-Caribbean respondents reported high work stress than either Bangladeshi or white respondents. Reported racial discrimination among black African-Caribbean female respondents was strongly associated with perceived work stress. Among the black African-Caribbean respondents, women who reported experiencing racial discrimination at work had higher levels of psychological distress. CONCLUSIONS Perceived work stress may be underpinned by exposure to racial discrimination at work among black African-Caribbean women, and this may affect their psychological well-being.
Nipple Pain in Breastfeeding Mothers: Incidence, Causes and Treatments

Background: Persistent nipple pain is one of the most common reasons given by mothers for ceasing exclusive breastfeeding. We aimed to determine the frequency of nipple pain as a reason for consultation, the most common attributed aetiologies, and the effectiveness of the advice and treatment given. Methods: All consultations at the Breast Feeding Centre of Western Australia (WA) were audited over two six-month periods in 2011 (n = 469) and 2014 (n = 708). Attributed cause(s) of nipple pain, microbiology results, treatment(s) advised, and resolution of pain were recorded. Results: Nipple pain was one of the reasons for consultation in 36% of cases. The most common attributed cause of nipple pain was incorrect positioning and attachment, followed by tongue tie, infection, palatal anomaly, flat or inverted nipples, mastitis, and vasospasm. Advice included correction of positioning and attachment, use of a nipple shield, resting the nipples and expressing breastmilk, frenotomy, oral antibiotics, topical treatments, and cold or warm compresses. Pain was resolving or resolved in 57% of cases after 18 days (range 2–110). Conclusion: The multiple attributed causes of nipple pain, possibly as a result of a cascade of events, suggests that effective early lactation management for prevention of nipple pain and early diagnosis and effective treatment are crucial to avoid early weaning.
New Trade Union Activism: Class Consciousness or Social Identity?, by Sian Moore

Author biography Philip Roberts is a second-year Ph.D. candidate in the Department of Politics and International Relations, University of Nottingham. He is also a fellow of the Centre for the Study of Social and Global Justice (CSSGJ). His research focuses on the Landless Workers Movement of Brazil, and seeks to apply the work of Marxist theorists including Antonio Gramsci and Henri Lefebvre to questions of space, ideology, state formation and class strategy. His work is funded by a Nottingham University Faculty of Social Sciences bursary.
A Stringent Authorization using Principles and Policy for Grid Computing

Problem statement: The current information security mechanisms are in sufficient to address authorization issues. The access control mo dels today are mostly static and they are not well- suited for the service-oriented environments where information access is dynamic in nature. Traditional authorization security techniques do no t directly address these concerns as they primarily use access control lists for authorization, where t he user whose name appears in the list is authorize d to access the grid with some privileges associated wit h the names, which requires the resource provider t o maintain authorization decisions for every user, wh ich is very time consuming and non-scalable solution. Approach: Organizations pass user roles instead of name and date of birth but it used Public Key Infrastructure user certificate for authorizati on which is inflexible when it comes to open distributed systems (Grid) as it assumes a pre-agre ed trust between Service Provider and the Service consumer. Usage of Java authentication and authoriz ation services is performed in a pluggable fashion. It permits the application to remain indep endent from underlying authentication technology. Results: Our implementation provides service providers with full control over authentication and authorization of accounts that access services. Imp lementation of the proposed technique has proved to be less time consuming and more secured for auth entication and authorization as compared to the traditional way of authenticating the users. The Po licy Decision Service is envisioned to be used by many Web services protected by their PEPs. Conclusion: The model brings out many advantages over traditional identity. It is more flexible and more powerful and is suited for dynamic environments for Web services.
Du mode de définition de deux programmes de recherche en sociologie et en ethnométhodologie

Ce texte examine la façon dont un courant de recherche sociologique définit son programme, ses méthodes et son épistémologie1. Les oppositions constitutives de toute définition étant polarisées, un programme de recherche comporte de nombreux éléments négatifs (au sens de négation). Ce dossier «science et pathologie» est l’occasion d’interroger ces oppositions ordonnées et les éléments négatifs d’un programme de recherche. La pathologie est différente selon qu’elle vise un mode de connaissance non scientifique ou un paradigme scientifique, ses implications sont différentes selon que la comparaison est envisagée sur le mode de l’hétérogénéité, de la continuité ou de la critique. Le niveau d’analyse de cet article est concret : les considérations d’ordre général sur la science ou la sociologie seront évitées. Sa portée est limitée à l’étude de la définition de deux programmes de recherche qui ont marqué la sociologie : les Studies in ethnomethodology de Harold Garfinkel et Le métier de sociologue de Pierre Bourdieu, JeanClaude Chamboredon et Jean-Claude Passeron. Le choix de ces deux textes fut guidé par la place importante qu’ils occupent dans l’histoire de la sociologie et par leur contemporanéité (une année seulement sépare leur publication).
Mass transit: Epithelial morphogenesis in the Drosophila egg chamber

Epithelial cells use a striking array of morphogenetic behaviors to sculpt organs and body plans during development. Although it is clear that epithelial morphogenesis is largely driven by cytoskeletal rearrangements and changes in cell adhesion, little is known about how these processes are coordinated to construct complex biological structures from simple sheets of cells. The follicle cell epithelium of the Drosophila egg chamber exhibits a diverse range of epithelial movements in a genetically accessible tissue, making it an outstanding system for the study of epithelial morphogenesis. In this review, we move chronologically through the process of oogenesis, highlighting the dynamic movements of the follicle cells. We discuss the cellular architecture and patterning events that set the stage for morphogenesis, detail individual cellular movements, and focus on current knowledge of the cellular processes that drive follicle cell behavior. Developmental Dynamics 232:559–574, 2005. © 2005 Wiley‐Liss, Inc.
A review of web-based technology in behavioural activation

Objective This article aims to describe emerging web-based behavioural activation to illustrate technology features currently available or under development and investigation. We describe how recent challenges to psychotherapy could be successfully addressed using web-based approaches. These challenges involve the need for greater reach, the need to evaluate mediation for interventions, and the need to address whether web-based interventions maintain treatment integrity (TI) as demonstrated in face-to-face delivery. Method We selected five emerging web-based interventions that have shown initial efficacy based on a PsychInfo search in July 2015. The models chosen are illustrative of the range of technology features that are consistent with behavioural activation implementation and afford the capability of achieving greater reach and advancing both mediation and TI analyses. Results Our investigation revealed three basic points. First, technology can assist dissemination such that greater reach is achieved. Second, this can be done while validating TI. Finally, we propose how mediation and TI analyses can become more widespread and population-specific through the adoption of a technology-based approach. Conclusions The adoption of behavioural intervention technology presents opportunities that include (1) achieving client reach unconstrained by geo-specific location of the home base of clinician-researchers; (2) providing a clearer demonstration of therapy mediation in the simplest terms; and (3) identifying if essential features were delivered as a way of preserving integrity.
The preventive effect of dexmedetomidine on paroxysmal sympathetic hyperactivity in severe traumatic brain injury patients who have undergone surgery: a retrospective study

Background Paroxysmal sympathetic hyperactivity (PSH) results and aggravates in secondary brain injury, which seriously affects the prognosis of severe traumatic brain injury patients. Although several studies have focused on the treatment of PSH, few have concentrated on its prevention. Methods Ninety post-operation (post-op) severe traumatic brain injury (sTBI) patients admitted from October 2014 to April 2016 were chosen to participate in this study. Fifty of the post-op sTBI patients were sedated with dexmedetomidine and were referred as the “dexmedetomidine group” (admitted from May 2015 to April 2016). The other 40 patients (admitted from October 2014 to May 2015) received other sedations and were referred as the “control group. ” The two groups were then compared based on their PSH scores and the scores and ratios of those patients who met the criteria of “probable,” “possible” and “unlikely” using the PSH assessment measure (PSH-AM) designed by Baguley et al. (2014). The durations of the neurosurgery intensive care unit (NICU) and hospital stays and the Glasgow outcome scale (GOS) values for the two groups were also compared to evaluate the therapeutic effects and the patients’ prognosis. Results The overall PSH score for the dexmedetomidine group was 5.26 ± 4.66, compared with 8.58 ± 8.09 for the control group. The difference between the two groups’ PSH scores was significant (P = 0.017). The score of the patients who met the criterion of “probable” was 18.33 ± 1.53 in the dexmedetomidine group and 22.63 ± 2.97 in the control group, and the difference was statistically significant (P = 0.045). The ratio of patients who were classified as “unlikely” between the two groups was statistically significant (P = 0.028); that is, 42 (84%) in the dexmedetomidine group and 25 (62.5%) in the control group. The differences in NICU, hospital stays and GOS values between the two groups were not significant. Conclusion Dexmedetomidine has a preventive effect on PSH in sTBI patients who have undergone surgery.
Structure and function of telomeres.

TELOMERES DEFINED . 579 TELOMERE FUNCTION . 580 SEQUENCE AND STRUCTURE OF TELOMERES . 581 SOLUTIONS FOR REPLICATION OF DNA TERMINI . 586 STRUCTURE OF SUBTELOMERIC REGIONS. 589 FORMA TION OF TELOMERES . 591 PROTEINS THAT INTERACT WITH TELOMERES . 594 ARE TELOMERES REALLY ESSENTIAL? 597 FUTURE PROSPECTS . 598
Role of muscle-derived cells in hematopoietic reconstitution of irradiated mice.

To the editor: Role of muscle-derived cells in hematopoietic reconstitution of irradiated mice In the process of embryonic development, all cells arise from one common cell, the fertilized egg. Similarly, all mesodermal tissues are derived from a common undifferentiated ancestor. It is not known
State of the art of Laser Hardening and Cladding

In this paper an overview is given about laser surface modification processes, which are developed especially with the aim of hardness improvement for an enhanced fatigue and wear behaviour. The processes can be divided into such with and without filler material and in solid-state and melting processes. Actual work on shock hardening, transformation hardening, remelting, alloying and cladding is reviewed, where the main focus was on scientific work from the 21st century.