Miracle-dz/UniFAR-FTUs huggingface dataset:
Extent and direction of arterial remodeling in stable versus unstable coronary syndromes : an intravascular ultrasound study.

BACKGROUND The morphological characteristics of coronary plaques in patients with stable versus unstable coronary syndromes have been described in vivo with intravascular ultrasound, but the relationship between arterial remodeling and clinical presentation is not well known. METHODS AND RESULTS We studied 85 patients with unstable and 46 patients with stable coronary syndromes using intravascular ultrasound before coronary intervention. The lesion site and a proximal reference site were analyzed. The remodeling ratio (RR) was defined as the ratio of the external elastic membrane (EEM) area at the lesion to that at the proximal reference site. Positive remodeling was defined as an RR >1.05 and negative remodeling as an RR <0.95. Plaque area (13.9+/-5.5 versus 11.1+/-4.8 mm(2); P=0.005), EEM area (16.1+/-6.2 versus 13.0+/-4.8 mm(2); P=0. 004), and the RR (1.06+/-0.2 versus 0.94+/-0.2; P=0.008) were significantly greater at target lesions in patients with unstable syndromes than in patients with stable syndromes. Positive remodeling was more frequent in unstable than in stable lesions (51. 8% versus 19.6%), whereas negative remodeling was more frequent in stable lesions (56.5% versus 31.8%) (P=0.001). CONCLUSIONS Positive remodeling and larger plaque areas were associated with unstable clinical presentation, whereas negative remodeling was more common in patients with stable clinical presentation. This association between the extent of remodeling and clinical presentation may reflect a greater tendency of plaques with positive remodeling to cause unstable coronary syndromes.
Building Ego Factors through the Curriculum

Children in the Dubnoff School for Educational Therapy have problems ranging from neurological dysfunction and learning disabilities to mental retardation and overt psychoses. One common denominator for all of them, regardless of whether the insult to the organism is organic or psychogenic, is a deficiency in ego strength. This paper deals first with the psychological rationale operative throughout the Dubnoff School which is based on the work of ego psychologists, Erik Erikson in particular. Erikson's framework sets for us the task of a step-by-step development of ego identity. This has pointed our work in the direction of building ego strength through mastery. Multi-dimensional programs which have evolved over many years to help overcome ego deficiency are described.
Inventing the Internet

From the Publisher: In Inventing the Internet, Janet Abbate focuses on the social and cultural factors that influenced the Internet's design and use. She unfolds an often twisting tale of collaboration and conflict among a remarkable variety of players, including government and military agencies, computer scientists in academia and industry, graduate students, telecommunications companies, standards organizations, and network users.
Divergence and biogeography of the recently evolved Macaronesian red Festuca (Gramineae) species inferred from coalescence‐based analyses

Studying the biogeography and the phylogeography of the endemic Macaronesian red Festuca species (Loliinae, Poaceae) is of prime interest in understanding the speciation and colonization patterns of recently evolved groups in oceanic archipelagos. Coalescence‐based analyses of plastid trnLF sequences were employed to estimate evolutionary parameters and to test different species‐history scenarios that model the pattern of species divergence. Bayesian IM estimates of species divergence times suggested that ancestral lineages of diploid Macaronesian and Iberian red fescues could have diverged between 1.2 and 1.57 Ma. When empirical data were compared to coalescence‐based simulated distributions of discordance and p‐distance statistics, two species‐history models were chosen in which the first branching lineage derived in Canarian Festuca agustinii. Its sister lineage could have involved a recent polytomy leading to the Madeiran Festuca jubata, the Azorean Festuca francoi + Festuca petraea and the continental Festuca rivularis lineages (Canarian model) or the sequential branching of lineages leading to F. jubata and finally to the sister clades of F. rivularis and F. francoi + F. petraea (Sequential model). Nested clade phylogeographic analysis (NCPA) and a first adapted host–parasite co‐evolutionary ParaFit method were used to detect the phylogeographic signal. NCPA inferred long‐distance colonizations for the entire diploid red Festuca complex, but allopatric‐fragmentation and isolation‐by‐distance (IBD) patterns were inferred within archipelagos. In addition, the ParaFit method suggested a generalized pattern of a stepping‐stone model at all hierarchical levels. Maximum‐likelihood‐based dispersal‐extinction‐cladogenesis (DEC) models were superimposed on the Sequential model species tree. The three‐independent‐colonization (3IC) model was the best supported biogeographic scenario, concurring with previous analysis based on multilocus AFLP data.
Marking feminist times: Remembering the longest revolution in Australia

Margaret Henderson’s Marking Feminist Times: Remembering the Longest Revolution in Australia is the first book-length study to interrogate the construction of an Australian feminist past (and feminism as having past) across a broad range of sources: ‘popular’ feminist histories, autobiographies, novels, journalism, radio, film and television, and men’s movement texts are all analysed as important sites of memory work. Henderson’s theoretical frame is Freudian, as she emphasizes that the fraught process of cultural memory is deeply implicated in unconscious processes of mourning and melancholy. The book’s structure, part of Henderson’s laudable search for a ‘poetics of cultural remembrance’, works well and enables her to ask the following questions across a range of genres: ‘how does the form of text mediate and possibly constrain the types of pasts narrated? Which forms are more prevalent as spaces of historical enunciation? ’ (p. 20). For Henderson, a revolutionary feminism is the ‘lost love object’, that is either mourned (as in reluctantly relinquished) or is the subject of melancholy, resulting from the failure or inability to perform the detachment that is an ineluctable part of mourning: ‘either a process of working through real or imagined loss, or of holding on’ (p. 242). In order to come to terms with the historicization of second-wave feminism as a public process, Henderson moves deftly from feminism’s ‘insides’ to its ‘outside’. That is, from remembrances produced by those claiming a speaking position within the women’s movement to those commentators/writers/journalists whose goal in constructing a past for feminism often has an altogether different ideological inflection. In this way, Henderson is concerned with the kinds of discourses, tropes and metaphors through which both feminists and those with a tangential relationship to feminism, one of hostility, or none at all, come to conceptualize its past. This should not imply a separation into ‘authentic’ feminist histories and those produced outside its boundaries; on the contrary, throughout Henderson is conscious of the inevitable permeability of these two sites of remembrance, a fact which is particularly evident in her chapter on journalism. As she emphasizes in Chapter 1, until the mid-1990s the modern Australian women’s movement had not been subject to extended historical analysis. This chapter analyses a number of texts produced at this juncture: Gisela Kaplan’s The Meagre Harvest, Marilyn Lake’s Getting Equal, Chilla Bulbeck’s Living Feminism and Jean Curthoys’ tellingly entitled Feminist Amnesia. Identifying their key textual strategies, Henderson shows how the necessarily interested memory work performed by these feminist academics produces at times conflicting pasts. Chapter 2 takes the field of feminist autobiography as its subject, and analyses the first autobiography of a prominent Australian feminist (Zelda Z’prano’s Zelda) prior to examining the individualist narratives of high-profile Australian
Applications of storage mapping optimization to register promotion

Storage mapping optimization is a flexible approach to folding array dimensions in numerical codes. It is designed to reduce the memory footprint after a wide spectrum of loop transformations, whether based on uniform dependence vectors or more expressive polyhedral abstractions. Conversely, few loop transformations have been proposed to facilitate register promotion, namely loop fusion, unroll-and-jam or tiling. Building on array data-flow analysis and expansion, we extend storage mapping optimization to improve opportunities for register promotion.Our work is motivated by the empirical study of a computational biology benchmark, the approximate string matching algorithm BPR from NR-grep, on a wide issue micro-architecture. Our experiments confirm the major benefit of register tiling (even on non-numerical benchmarks) but also shed the light on two novel issues: prior array expansion may be necessary to enable loop transformations that finally authorize profitable register promotion, and more advanced scheduling techniques (beyond tiling and unroll-and-jam) may significantly improve performance in fine-tuning register usage and instruction-level parallelism.
Real-Time Reshaping of Humans

We present a system for real-time deformation of the shape and appearance of people who are standing in front of a depth+RGB camera, such as the Microsoft Kinect. Our system allows manipulating human body shape parameters such as height, muscularity, weight, waist girth and leg length. The manipulated appearance is displayed in realtime. Thus, instead of posing in front a real mirror and visualizing their appearance, users can pose in front of a 'virtual mirror' and visualize themselves in different body shapes. Our system is made possible by a morphable model of 3D human shape that was learnt from a large database of 3D scans of people in various body shapes and poses. In an initialization step, which lasts a couple of seconds, this model is fit to the 3D shape parameters of the people as observed in the depth data. Then, a succession of pose tracking, body segmentation, shape deformation and image warping steps are performed -- in real-time and independently for multiple people. We present a variety of results in the paper and the video, showing the interactive virtual mirror cabinet experience.
Emotions in climbing: a design opportunity for haptic communication

This paper presents the results of 11 interviews to beginner climbers aimed at investigating the role of emotions in learning climbing. Climbing is an extreme sport becoming increasingly popular thanks to a higher safety and to the spread of indoor gyms. Although the evolution of this sport from alpinism to indoor practice has made it accessible to all, the emotional involvement that it entails has remained. Our findings suggest that there can be a space for the design of technologies that help managing negative emotions by augmenting the communication between climbing partners with haptic feedback.
Granulocyte Transit from Bone Marrow to Blood

T HE TEMPORAL COURSE of granulocyte development has been rather well characterized.1’2 However, there is still a good deal of uncertainty about the behavior of the mature granulocytes in bone marrow. Interpretation of the chronology of appearance of mature cells after DNA labeling is open to question because of the unavoidable contamination of marrow samples with blood and possibly for other reasons as well. Thus, relatively little is known about the time spent by a mature granulocyte in the bone marrow and about the nature of its release to the circulating blood; for example, whether this follows first in-first out kinetics or is essentially a simple random process as in the case of granulocyte removal from blood. We have approached the problem indirectly by making a closely spaced study of the rise and fall of the progeny of presumably a single generation of tritiated thymidine labeled granulocytes in the blood of the dog. It was possible in this way to determine that granulocyte release from marrow was normally distributed with a mean time from labeling as a myelocyte to appearance in blood of 102 ± 13.8 hours.
High lung inflation increases mRNA levels of ECM components and growth factors in lung parenchyma.

Remodeling of pulmonary capillaries occurs after chronic increases in capillary pressure (e.g., mitral stenosis). Also, remodeling of pulmonary arteries begins within 4 h of increased wall stress and is endothelium dependent. We have previously shown that high lung inflation increases wall stress in pulmonary capillaries. This study was designed to determine whether high lung inflation induces remodeling of the extracellular matrix (ECM) in lung parenchyma. Open-chest rabbits were ventilated for 4 h with 9-cmH2O positive end-expiratory pressure (PEEP) on one lung and 1-cmH2O PEEP on the other (High-PEEP group), or with 2-cmH2O PEEP on both lungs (Low-PEEP group). An additional untreated control group was also included. We found increased levels of mRNA in both lungs of High-PEEP rabbits (compared with both the Low-PEEP and untreated groups) for alpha1(III) and alpha2(IV) procollagen, fibronectin, basic fibroblast growth factor, and transforming growth factor-beta1. In contrast, alpha2(I) procollagen and vascular endothelial growth factor mRNA levels were not changed. We conclude that high lung inflation for 4 h increases mRNA levels of ECM components and growth factors in lung parenchyma.
Construct validity of material-specific memory measures following unilateral temporal lobe ablations.

Material-specific memory test performance of 18 left (LTL), and 11 right (RTL), unilateral temporal lobectomy patients was assessed pre- and 1 wk postsurgery. Selective Reminding and Serial Digit Learning tests were the verbal, and Complex Figure and Form Sequence Learning tests were the nonverbal, learning measures. Reasons for the difficulty in finding «pure» measures of visual learning are discussed, and suggestions for future nonverbal memory test development are presented
A Spurious-Power Suppression technique for a Low-Power Multiplier

This paper presents the design exploration of a spurious-power suppression technique (SPST) which can dramatically reduce the power dissipation of combinational VLSI designs for multimedia/DSP purposes. The proposed SPST separates the target designs into two parts, i.e., the most significant part and least significant part (MSP and LSP), and turns off the MSP when it does not affect the computation results to save power. The objective of a good multiplier is to provide a physically compact, good speed and low power consuming chip. To save significant power consumption of a VLSI design, it is a good direction to reduce its dynamic power that is the major part of total power dissipation. In this paper, we propose a high speed lowpower multiplier adopting the new SPST implementing approach. This multiplier is designed by equipping the Spurious Power Suppression Technique (SPST) on a modified Booth encoder which is controlled by a detection unit using an AND gate. The modified booth encoder will reduce the number of partial products generated by a factor of 2. The SPST adder will avoid the unwanted addition and thus minimize the switching power dissipation. Keywords-Booth encoder; low power; spurious power suppression technique(SPST); SPST-Adder.
Thin film high temperature superconducting RF coils for low field MRI

We have built and tested a thin‐film high temperature superconducting (HTS) surface coil for MRI at 0.064T. When placed as close as possible to a conductive sample, the 6.7‐cm outer diameter HTS coil had a measured signal‐to‐noise ratio (SNR) 1.8; times higher than a room temperature copper coil of similar size and location. Our results predict that in some cases, SNR gains of about a factor of 2 can be attained in low‐field MRI systems by substituting HTS surface coils for copper coils.
Elicited Imitation in Children and Adults With Autism: the Effect of Different Types of Actions

Background: It was proposed by Rogers & Pennington (1991) that an early deficit in imitation, together with a cascade of developmental disorders in emotion sharing and Theory of Mind, could be important in understanding autism. Having already found that imitation appeared not to be specifically or universally impaired in autism, the present study tested whether there were distinctions between different types of actions, such as symbolic versus non-symbolic, one-handed versus two-handed or symmetrical versus asymmetrical actions, on a test of elicited imitation. Methods: A large battery of tasks was used to elicit imitation from three groups of autistic children and adults (aged 4–34 years of age), two groups of typically developing children and a group of children with mild-to-moderate intellectual disabilities. Results: The majority of children and adults with autism had few impairments relative to the controls, although certain actions did seem more difficult, especially for the youngest children. For example, actions within the categories of 'symbolic actions' and 'asymmetrical actions' seemed to give some groups more problems. Certain types of errors such as hand reversals and using body parts as objects were found in both autistic and non-autistic groups, but, for the most part, in the youngest children in the whole sample. A final analysis compared the number of partial imitations for eight specific actions. Conclusions: The overall picture was not one of an autism-specific deficit in imitation, but rather of a normal (i.e. age-related) developmental trend. These results are discussed in terms of Rogers & Pennington's theory and other leading theories.
Affective Computing: From Laughter to IEEE

This is an invited introduction to the first issue of the IEEE Transactions on Affective Computing, telling personal stories and sharing viewpoints of a pioneer and visionary of the field of Affective Computing. This article is not intended to be a thorough or a historical account of the development of the field, for the author is not a historian and cannot begin to properly credit the extraordinary efforts of hundreds of people who helped to cultivate and expand the rich and fertile landscape that extends before us now.
Life history determines biogeographical patterns of soil bacterial communities over multiple spatial scales

The extent to which the distribution of soil bacteria is controlled by local environment vs. spatial factors (e.g. dispersal, colonization limitation, evolutionary events) is poorly understood and widely debated. Our understanding of biogeographic controls in microbial communities is likely hampered by the enormous environmental variability encountered across spatial scales and the broad diversity of microbial life histories. Here, we constrained environmental factors (soil chemistry, climate, above‐ground plant community) to investigate the specific influence of space, by fitting all other variables first, on bacterial communities in soils over distances from m to 102 km. We found strong evidence for a spatial component to bacterial community structure that varies with scale and organism life history (dispersal and survival ability). Geographic distance had no influence over community structure for organisms known to have survival stages, but the converse was true for organisms thought to be less hardy. Community function (substrate utilization) was also shown to be highly correlated with community structure, but not to abiotic factors, suggesting nonstochastic determinants of community structure are important Our results support the view that bacterial soil communities are constrained by both edaphic factors and geographic distance and further show that the relative importance of such constraints depends critically on the taxonomic resolution used to evaluate spatio‐temporal patterns of microbial diversity, as well as life history of the groups being investigated, much as is the case for macro‐organisms.
Glucose estimation in the salivary secretion of diabetes mellitus patients

Aim Saliva is one of the most abundant secretions in the human body and its collection is easy and noninvasive. The aim of this study was to find a medium that can be used to diagnose and monitor diabetes. In this, saliva could play a major role. To substantiate the role of saliva as a diagnostic tool, we compared saliva samples with blood glucose and glycated hemoglobin (HbA1c) in healthy and diabetic subjects. Materials and methods Included in the study were 106 patients, newly diagnosed with type 2 diabetes mellitus and 15 healthy control subjects. The patients and control subjects were asked to come to the clinic in the morning, after an 8-hour fast. At that time, 5 mL of venous blood was collected, 2 mL of which was collected in an ethylenediaminetetraacetic acid (EDTA)-containing blood collection tube and sent for HbA1c estimation. Unstimulated saliva was collected from both groups as well. The saliva and sera from the blood samples were subjected to glucose estimation. Results The correlation coefficient between serum glucose and salivary glucose in the control group was calculated and the r value was found to be 0.5216, which was statistically significant (P < 0.05). The correlation coefficient between serum glucose and salivary glucose in the patient group was also calculated and the r value was found to be 0.7686, which was highly significant (P < 0.01). Finally, the correlation coefficient between HbA1c level and salivary glucose in the patient group was calculated and the r value was found to be 0.5662, which was also highly significant (P < 0.01).
Complete Genome Sequences of the Obligate Symbionts “Candidatus Sulcia muelleri” and “Ca. Nasuia deltocephalinicola” from the Pestiferous Leafhopper Macrosteles quadripunctulatus (Hemiptera: Cicadellidae)

ABSTRACT Two bacterial symbionts of the European pest leafhopper, Macrosteles quadripunctulatus (Hemiptera: Cicadellidae), were fully sequenced. “Candidatus Sulcia muelleri” and “Ca. Nasuia deltocephalinicola” represent two of the smallest known bacterial genomes at 190 kb and 112 kb, respectively. Genome sequences are nearly identical to strains reported from the closely related host species, M. quadrilineatus.