Miracle-dz/UniFAR-FTUs huggingface dataset:
Long-term outcomes of proximal interphalangeal joint surface replacement arthroplasty.

BACKGROUND Surface replacement arthroplasty is a reconstructive alternative for the treatment of pain and deformity due to osteoarthritis and rheumatoid arthritis of the proximal interphalangeal joint of the finger. This retrospective study was performed to examine long-term outcomes of proximal interphalangeal joint prosthetic surface replacement with a proximal cobalt-chromium (CoCr) and distal ultra-high molecular-weight polyethylene component over thirty years at a single institution. METHODS Sixty-seven prostheses were implanted in forty-seven patients between 1974 and 2007. The mean duration of follow-up was 8.8 years. There were fifty joints (75%) with osteoarthritis and seventeen (25%) with rheumatoid arthritis. Fifty-six prostheses (84%) were implanted via a dorsal approach, forty-eight (72%) were cemented, and nineteen (28%) were press-fit. Postoperative evaluation, consisting of a clinical history and examination, radiographs, the Short Form-36 (SF-36) and Disabilities of the Arm, Shoulder and Hand (DASH) questionnaires, and a visual analog scale (VAS) pain score, was performed for thirty-six patients. Demographic, surgical, and implant failure data were obtained from the medical charts of eleven patients (sixteen implants) who had died prior to the time of postoperative follow-up. RESULTS At the time of follow-up, the median total active proximal interphalangeal joint motion was 40°. Eight prostheses had failed, yielding a cumulative incidence of implant failure of 3% at one year, 8% at three years, 11% at five years, and 16% at fifteen through twenty-five years. Prostheses implanted via a volar approach failed more often than those implanted via a dorsal approach (relative risk: 6.59, p = 0.004). The failure rate did not differ significantly between patients with rheumatoid arthritis and those with osteoarthritis (p = 0.17). The median VAS pain score at the time of follow-up was 3 (of a maximum of 100). There were twenty-two complications in fourteen patients, resulting in four interphalangeal fusions and two amputations. There were no infections. CONCLUSIONS Proximal interphalangeal surface replacement arthroplasty is a reliable treatment alternative for pain and deformity due to proximal interphalangeal joint osteoarthritis and rheumatoid arthritis. At the time of long-term follow-up, pain was minimal and joint motion was similar to preoperative levels.
GENITAL ULCER DISEASE

Genital ulcers may present the medical profession with a diagnostic dilemma. Ulcers may form on the genitals in a variety of conditions. ''^ The etiology varies with the age of the patient. In the elderly, premalignancies or malignancies must be suspected, ln children, genital ulcers are rarely found and are commonly due to diaper dermatitis. In the sexually active person, sexually transmitted diseases (STD) may be responsible for genital ulcers. It is convenient to divide genital ulcers into two groups, namely those caused by venereal and those caused by nonvenereal disease (Table 1). If ulcerations develop simultaneously on the genitals and on other parts of the body, a venereal cause is less likely. ' Frequent nonvenereal causes of genital ulcers are listed in Table 1. In different regions of the world, different etiologies are responsible for genital ulcer disease (GUD) (Table 2). In the United States, the majority of genital ulcers are caused by genital herpes. ^ The incidence of syphilis in 1987 was the highest since 1950. '' Venereal diseases like lymphogranuloma venereum, chancroid, and donovanosis occur only sporadically or in small outbreaks. In many developing countries, genital ulcerations are common, among numerous other STDs. ''"" In many African countries, chancroid is the most frequent cause of genital ulcers, and lymphogranuloma venereum and donovanosis are still prevalent. '''''•*'''̂ In Papua New Guinea, donovanosis is still widely prevalent,'and genital herpes is rarely diagnosed. '" Under circumstances with no available laboratory facilities, unravelling the cause of genital ulcerations provides extra difficulties and is frequently impossible. The diagnosis is usually based on clinical findings only. In the management of genital ulcers, laboratory investigations are indicated, for most of which a wellequipped laboratory setting is a prerequisite. Most commonly used techniques are summarized in Table 3. Fven with sophisticated modern laboratory techniques.
Relationship between factor XIII activity, fibrinogen, haemostasis screening tests and postoperative bleeding in cardiopulmonary bypass surgery

Summary We investigated the relationship between factor XIII, fibrinogen, blood coagulation screening tests and postoperative bleeding in 98 patients undergoing cardiopulmonary bypass (CPB) surgery. All patients received aprotinin. Blood samples were collected preoperatively (T1), after termination of CPB (T2), 12 h (T3) and 24 h (T4) after surgery to determine FXIII activity, fibrinogen, platelet count, prothrombin time (PT), activated partial thromboplastin time (APTT) and D-dimers (DD). Laboratory results were correlated with the chest tube drainage 24 h after surgery and compared between patients with 24-hour chest tube drain volumes in the lower (Group 1) with those in the upper tertile (Group 3). Median FXIII and fibrinogen levels dropped by 33.9% and 34.2%, respectively, during CPB. No association between FXIII activity and the extent of postoperative bleeding was found. However, chest tube bleeding was significantly correlated with preoperative and postoperative fibrinogen. This was confirmed by comparing Groups 1 and 3. Group 3 patients had significantly lower fibrinogen levels than Group 1 at T1 – T4, although most fibrinogen values were within or above the reference range (medians, g/l: 3.5 vs. 4.0, p = 0.043 at T1; 2.3 vs. 2.7, p = 0.015 at T2; 2.9 vs. 3.3, p = 0.008 at T3; 4.2 vs. 5.2, p = 0.002 at T4). There was also a significant relationship of platelet count, PT and APTT, as measured after CPB (T2), with postoperative chest tube drainage. In conclusion, plasma FXIII activity does not influence postoperative bleeding in patients undergoing CPB surgery. There is however an inverse association between preoperative or postoperative plasma fibrinogen levels and postoperative bleeding. These findings indicate a modulation of postoperative bleeding by fibrinogen levels.
Selected papers on analysis of algorithms

Amazon.com: Selected Papers on Design of Algorithms Center for the Study of Language and Information. Selected Papers on the Analysis of Algorithms.by Donald E. Knuth Stanford, California: Center for the Study of Language and Information, 2000, xvi621 pp. Selected Papers on Design of Algorithms. The fourth was Selected Papers on Analysis of Algorithms the fifth was Selected Papers on Computer Languages.This is a list of Selected papers series: written by Donald Knuth. Knuth, Selected Papers on Analysis of Algorithms Stanford, California: Center for.equal footing with selection sort and quicksort in online. A 1956 reference 10 to an analysis of the algorithm. Also in Selected Papers on Analysis of.Think of analysis as the measurement of. The habit of using algorithm analysis to justify design de. We use two algorithms for selection as examples for the.This paper considers a number of selection schemes commonly used in. Or that selection scheme in genetic algorithms GAs, but most of these are based.This site contains design and analysis of various computer algorithms such as. Matrix-chain Multiplication Knapsack Problem DP Solution Activity Selection Problem DP Solution.
Educational Nursing Program Implementation: It’s Effect on Hepatic Encephalopathy Severity among Patients with Liver Cirrhosis

: Hepatic encephalopathy one of the most serious complications of liver diseases which is responsible for the major cause of admission and high mortality in cirrhotic patients. So effective educational nursing intervention may be of great value in minimizing hepatic encephalopathy episode. Purpose : was to examine the effect of educational nursing program on hepatic encephalopathy severity among patients with liver cirrhosis. Design : a quasi-experimental research design was utilized. Setting : The current study was carried out at endemic diseases department and the outpatient clinics of Menoufia University Hospital as well as National Liver Institute at Shebin El-Kom, Menoufia Governorate, Egypt. Subjects : A consecutive sample of 100 adult patients with liver cirrhosis were assigned randomly and alternatively into two equal groups, 50 patients for each group. Instruments : Three instruments were used for data collection: Structure interview questionnaire, bio - physiological measurement instrument and West-Haven criteria scale (WHC scale). Results : It is revealed that 92% and 96% of study and control groups respectively had poor total knowledge pre-intervention. While 90% and 86% respectively of study group compared to 0.0% of control group had good total knowledge level immediately post intervention and after 2 months. There was highly statistically significant reductions in hepatic encephalopathy severity grade among study group compared to control group immediately post intervention and after 2 months, in which majority of study group (88%) didn’t have hepatic encephalopathy abnormality compared to 48% of control group after 2 months of educational nursing intervention. Conclusions : Educational nursing program had a positive impact on reducing hepatic encephalopathy episodes and its severity among study group (group I) than control group (group II). Recommendations : Supervised health teaching should be given for all patients with liver cirrhosis to improve their knowledge and awareness about hepatic encephalopathy, its prevention and early detection especially for high risk persons. Also establishing a web site, including all information pertained to hepatic encephalopathy and all aspect of health education such as different educational materials, medias and audio-visual aids.
MANAGEMENT AND CONTROL PLAN FOR ZINFANDEL VINES IN SOUTH PASO ROBLES

Zinfandel, also known as Zin, is a red skinned variety of wine grape very popular in California. The wines produced from Zinfandel grapes have an intense fruitiness and luscious texture. Production is extremely variable throughout California and is dependent upon, climate, soil fertility, crop level management practices, and irrigation. This study was conducted to determine the on site soil physical and chemical properties as a means to obtain optimal yields and fruit quality. The A & L Western Agriculture Laboratories performed comprehensive fertility analysis to determine the concentrations of the plant essential nutrients, organic matter, electrical conductivity, cation exchange capacity, and pH in the soils. This site has experienced considerable soil disturbance during the rainy seasons due to the erosion of the Salinas River bank bordering the eastern side of the site as well as the non-vegetative ground to the north. Unfortunately, bare soil is highly susceptible to erosive losses. Valuable topsoil can be lost and areas can be deeply cut by gully erosion during the rainy season. The best erosion treatment is to take prevention measures. Therefore, it is recommended that any areas with bare soil be vegetated before next winter's rainy season. Irrigation rates should be adjusted throughout the year in accordance with annual precipitation, average wind speeds, average temperature, and the evapotranspiration rate. Special considerations should be made where irrigation water 4 could run off a steep slope. On these sites vegetation must be established, and measures taken to offset sediment loss due to erosion. Zinfandel vines appear to be sensitive to a variation in soil classifications and the effect of the loss of topsoil. With an improvement in land use management this specific site shows considerable potential to be a long term winemaking site. 5 ACKNOWLEDGEMENTS
Parallel Cardiac and Vascular Adaptation in Hypertension

BackgroundAlthough vascular damage in the noncoronary circulation is a major cause of complica-tions in hypertension, relatively little is known of the in vivo geometry and function of the arterial circulation in patients with uncomplicated hypertension or of their relation to left ventricular hypertro-phy, a marker of enhanced risk of cardiovascular complications. Methods and ResultsWall thickness and internal diameter of the common carotid artery and the presence of atherosclerosis within the extracranial carotid arteries were determined by ultrasound in 43 asymptomatic hypertensive patients and 43 normotensive subjects matched for sex, age, and body size. Vascular stiffness was estimated from simultaneous superimposed carotid pressure waveforms obtained with an external solid-state transducer. Left ventricular size and function were determined echocardio-graphically. Compared with normal subjects, hypertensive patients had greater left ventricular absolute and relative wall thicknesses, left ventricular mass, and carotid absolute and relative wall thicknesses (p < O.O05). Carotid intimal-medial thickness exceeded the 95th percentile of normal values in 28% of hypertensive patients (p < O.Ol). Carotid atherosclerosis was equally prevalent within the two blood pressure groups and was associated with older age, larger left ventricular and carotid wall thicknesses, and carotid diameter. Despite similar carotid pulse pressures, vascular stiffness was significantly increased in the hypertensive patients. Among the population as a whole, significant relations existed between cardiac and vascular wall thicknesses and internal dimensions. In multivariate analyses, these relations were statistically independent of age and blood pressure. ConclusionsThe present study documents the presence of geometric and functional changes within the common carotid artery in uncomplicated hypertension that parallel findings within the left ventricle. The potential contribution of these changes to the cardiovascular complications of hypertension, particularly in the setting of left ventricular hypertrophy, is unknown.
Phosphorylation of Exo1 modulates homologous recombination repair of DNA double-strand breaks

DNA double-strand break (DSB) repair via the homologous recombination pathway is a multi-stage process, which results in repair of the DSB without loss of genetic information or fidelity. One essential step in this process is the generation of extended single-stranded DNA (ssDNA) regions at the break site. This ssDNA serves to induce cell cycle checkpoints and is required for Rad51 mediated strand invasion of the sister chromatid. Here, we show that human Exonuclease 1 (Exo1) is required for the normal repair of DSBs by HR. Cells depleted of Exo1 show chromosomal instability and hypersensitivity to ionising radiation (IR) exposure. We find that Exo1 accumulates rapidly at DSBs and is required for the recruitment of RPA and Rad51 to sites of DSBs, suggesting a role for Exo1 in ssDNA generation. Interestingly, the phosphorylation of Exo1 by ATM appears to regulate the activity of Exo1 following resection, allowing optimal Rad51 loading and the completion of HR repair. These data establish a role for Exo1 in resection of DSBs in human cells, highlighting the critical requirement of Exo1 for DSB repair via HR and thus the maintenance of genomic stability.
Categorial Semantics for LFG

A categorial semantics for Lexical-khmctional Grammar provides a means for semantic interpretation of sentences of natural language that is appropriately constrained both syntactically and semantically. The f-structure of LFG provides a cross-lingnistically uniform format for representing syntactic information; constraining a derivation with respect to the f-structure rather than a phrase structure tree allows reference to relevant functional syntactic information without requiring construction of a phrase structure tree whose form is (often dubiously) motivated on semantic grounds. Additionally, a categorial semantics constrains semantic derivations appropriately, obviating the need for an appeal to wellformedness conditions on the resulting semantic representation.
Advancing Abstractive Bangla Text Summarization: A Deep Learning Approach Using Seq2seq Encoder- Decoder Model and T5 Transformer

Text summarization plays a vital role in distilling essential information from large volumes of text. While significant progress has been made in English text summarization using deep learning techniques, the research on Bangla text summarization remains limited, with most existing methods relying on non-deep learning approaches. This study addresses the scarcity of abstractive Bangla text summarization methods by conducting a comprehensive analysis using two deep learning models: Sequence-to-sequence (se q2se q) encoder-decoder model and T5 transformer. Through evaluation using BERT and ROUGE scores on the AUST NLP Research dataset and standard BNLPC datasets, this study reveals the Seq2seq model's superior performance in generating coherent abstractive summaries. According to the investigation's findings, the average F1-score is 0.8551, with average precision and recall of 0.8527 and 0.8578, respectively, determined through BERT score evaluations.
Effects of independently altering body weight and body mass on the metabolic cost of running

SUMMARY The metabolic cost of running is substantial, despite the savings from elastic energy storage and return. Previous studies suggest that generating vertical force to support body weight and horizontal forces to brake and propel body mass are the major determinants of the metabolic cost of running. In the present study, we investigated how independently altering body weight and body mass affects the metabolic cost of running. Based on previous studies, we hypothesized that reducing body weight would decrease metabolic rate proportionally, and adding mass and weight would increase metabolic rate proportionally. Further, because previous studies show that adding mass alone does not affect the forces generated on the ground, we hypothesized that adding mass alone would have no substantial effect on metabolic rate. We manipulated the body weight and body mass of 10 recreational human runners and measured their metabolic rates while they ran at 3 m s–1. We reduced weight using a harness system, increased mass and weight using lead worn about the waist, and increased mass alone using a combination of weight support and added load. We found that net metabolic rate decreased in less than direct proportion to reduced body weight, increased in slightly more than direct proportion to added load (added mass and weight), and was not substantially different from normal running with added mass alone. Adding mass alone was not an effective method for determining the metabolic cost attributable to braking/propelling body mass. Runners loaded with mass alone did not generate greater vertical or horizontal impulses and their metabolic costs did not substantially differ from those of normal running. Our results show that generating force to support body weight is the primary determinant of the metabolic cost of running. Extrapolating our reduced weight data to zero weight suggests that supporting body weight comprises at most 74% of the net cost of running. However, 74% is probably an overestimate of the metabolic demand of body weight to support itself because in reduced gravity conditions decrements in horizontal impulse accompanied decrements in vertical impulse.
Reshaping Anatomy Education – The Need of the Hour

Curricular reform in the anatomical sciences education is at cross roads. Many medical schools are continuing to modify their curriculum and educational methods with respect to anatomy. On one hand, the hours allotted for teaching anatomy has been significantly reduced, which prevents the anatomy educators from imparting their best to the students and on other hand, it has been dreaded that, because of the drastic reduction in time devoted to gross anatomy, ``the amount of detail in gross regional anatomy has now decreased below the safety level'' [1].
A CBR/RL system for learning micromanagement in real-time strategy games

The gameplay of real-time strategy games can be divided into macromanagement and micromanagement. Several researchers have studied automated learning for macromanagement, using a case-based reasoning/reinforcement learning architecture to defeat both static and dynamic opponents. Unlike the previous research, we present the Unit Priority Artificial Intelligence (UPAI). UPAI is a case-based reasoning/reinforcement learning system for learning the micromanagement task of prioritizing which enemy units to attack in different game situations, through unsupervised learning from experience. We discuss different case representations, as well as the exploration vs exploitation aspect of reinforcement learning in UPAI. Our research demonstrates that UPAI can learn to improve its micromanagement decisions, by defeating both static and dynamic opponents in a micromanagement setting.
A Hybrid Both Filter and Wrapper Feature Selection Method for Microarray Classification

Gene expression data is widely used in disease analysis and cancer diagnosis. However, since gene expression data could contain thousands of genes simultaneously, successful microarray classification is rather difficult. Feature selection is an important pre-treatment for any classification process. Selecting a useful gene subset as a classifier not only decreases the computational time and cost, but also increases classification accuracy. In this study, we applied the information gain method as a filter approach, and an improved binary particle swarm optimization as a wrapper approach to implement feature selection; selected gene subsets were used to evaluate the performance of classification. Experimental results show that by employing the proposed method fewer gene subsets needed to be selected and better classification accuracy could be obtained.
Decentralized and Energy-Efficient Workload Management in Enterprise Clouds

We present a decentralized approach towards scalable and energy-efficient management of virtual machine (VM) instances that are provisioned by large, enterprise clouds. In our approach, the computation resources of the data center are effectively organized into a hypercube structure. The hypercube seamlessly scales up and down as resources are either added or removed in response to changes in the number of provisioned VM instances. Without supervision from any central components, each compute node operates autonomously and manages its own workload by applying a set of distributed load balancing rules and algorithms. On one hand, underutilized nodes attempt to shift their workload to their hypercube neighbors and switch off. On the other, overutilized nodes attempt to migrate a subset of their VM instances so as to reduce their power consumption and prevent degradation of their own resources, which in turn may lead to SLA violations. In both cases, the compute nodes in our approach do not overload their counterparts in order to improve their own energy footprint. An evaluation and comparative study of the proposed approach provides evidence of its merits in terms of elasticity, energy efficiency, and scalability, as well as of its feasibility in the presence of high workload rates.