Miracle-dz/UniFAR-FTUs huggingface dataset:
Translating the complexities of flood risk science using KEEPER – a knowledge exchange exploratory tool for professionals in emergency response

Within flood risk management (FRM) decision making, there is a growing interest in participatory approaches to engage and integrate stakeholder expertise. Decision support tools are becoming common features in the FRM ‘toolkit’, yet there is a limited application of participatory methodologies in the construction of such tools. This paper reports on completed FRMRC research (Flood Risk Management Research Consortium, UK http://www.floodrisk.org.uk/) and the construction of a geographic information system‐based flood risk assessment tool, KEEPER – a Knowledge Exchange Exploratory tool for Professionals in Emergency Response. An iterative methodology was used to engage emergency professionals throughout the research process, allowing a mixing of scientific and professional expertise in the co‐production of KEEPER. KEEPER was both instrumental in facilitating participation and knowledge exchange, and informing recommendations for future tools in practice. This paper argues that participation is both essential for supporting pragmatic flood research and as a means of enhancing communication across traditionally divided communities.
Clustering-based evolution control for surrogate-assisted particle swarm optimization

When using a fixed number of neighbors for training a local surrogate model in surrogate assisted evolutionary optimization algorithms, it may suffer from the large uncertainty because the actual distribution of candidate's neighborhood may be neglected. In this paper, we propose to firstly analyze the distribution characteristics of candidate's neighborhood through a modified overlapping clustering method before training a local surrogate, and then use the clustering based evolution control strategy or model management strategy to facilitate the evolutionary algorithm to converge to the right optimum. Simulation results on four widely used benchmark functions demonstrate the efficacy of the proposed method.
Color Changes Upon Cooling of Lepidoptera Scales Containing Photonic Nanoarchitectures, and a Method for Identifying the Changes

Abstract The effects produced by the condensation of water vapor from the environment in the various intricate nanoarchitectures occurring in the wing scales of several Lepidoptera species were investigated by controlled cooling (from 23° C, room temperature to -5 to -10° C) combined with in situ measurements of changes in the reflectance spectra. It was determined that all photonic nanoarchitectures giving a reflectance maximum in the visible range and having an open nanostructure exhibited alteration of the position of the reflectance maximum associated with the photonic nanoarchitectures. The photonic nanoarchitectures with a closed structure exhibited little to no alteration in color. Similarly, control specimens colored by pigments did not exhibit a color change under the same conditions. Hence, this method can be used to identify species with open photonic nanoarchitectures in their scales. For certain species, an almost complete disappearance of the reflectance maximum was found. All specimens recovered their original colors following warming and drying. Cooling experiments using thin copper wires demonstrated that color alterations could be limited to a width of a millimeter or less. Dried museum specimens did not exhibit color changes when cooled in the absence of a heat sink due to the low heat capacity of the wings.
Distinct Lineages of Schistocephalus Parasites in Threespine and Ninespine Stickleback Hosts Revealed by DNA Sequence Analysis

Parasitic interactions are often part of complex networks of interspecific relationships that have evolved in biological communities. Despite many years of work on the evolution of parasitism, the likelihood that sister taxa of parasites can co-evolve with their hosts to specifically infect two related lineages, even when those hosts occur sympatrically, is still unclear. Furthermore, when these specific interactions occur, the molecular and physiological basis of this specificity is still largely unknown. The presence of these specific parasitic relationships can now be tested using molecular markers such as DNA sequence variation. Here we test for specific parasitic relationships in an emerging host-parasite model, the stickleback-Schistocephalus system. Threespine and ninespine stickleback fish are intermediate hosts for Schistocephalus cestode parasites that are phenotypically very similar and have nearly identical life cycles through plankton, stickleback, and avian hosts. We analyzed over 2000 base pairs of COX1 and NADH1 mitochondrial DNA sequences in 48 Schistocephalus individuals collected from threespine and ninespine stickleback hosts from disparate geographic regions distributed across the Northern Hemisphere. Our data strongly support the presence of two distinct clades of Schistocephalus, each of which exclusively infects either threespine or ninespine stickleback. These clades most likely represent different species that diverged soon after the speciation of their stickleback hosts. In addition, genetic structuring exists among Schistocephalus taken from threespine stickleback hosts from Alaska, Oregon and Wales, although it is much less than the divergence between hosts. Our findings emphasize that biological communities may be even more complex than they first appear, and beg the question of what are the ecological, physiological, and genetic factors that maintain the specificity of the Schistocephalus parasites and their stickleback hosts.
Evaluation of Candidate Reference Genes for Gene Expression Normalization in Brassica juncea Using Real Time Quantitative RT-PCR

The real time quantitative reverse transcription PCR (qRT-PCR) is becoming increasingly important to gain insight into function of genes. Given the increased sensitivity, ease and reproducibility of qRT-PCR, the requirement of suitable reference genes for normalization has become important and stringent. It is now known that the expression of internal control genes in living organism vary considerably during developmental stages and under different experimental conditions. For economically important Brassica crops, only a couple of reference genes are reported till date. In this study, expression stability of 12 candidate reference genes including ACT2, ELFA, GAPDH, TUA, UBQ9 (traditional housekeeping genes), ACP, CAC, SNF, TIPS-41, TMD, TSB and ZNF (new candidate reference genes), in a diverse set of 49 tissue samples representing different developmental stages, stress and hormone treated conditions and cultivars of Brassica juncea has been validated. For the normalization of vegetative stages the ELFA, ACT2, CAC and TIPS-41 combination would be appropriate whereas TIPS-41 along with CAC would be suitable for normalization of reproductive stages. A combination of GAPDH, TUA, TIPS-41 and CAC were identified as the most suitable reference genes for total developmental stages. In various stress and hormone treated samples, UBQ9 and TIPS-41 had the most stable expression. Across five cultivars of B. juncea, the expression of CAC and TIPS-41 did not vary significantly and were identified as the most stably expressed reference genes. This study provides comprehensive information that the new reference genes selected herein performed better than the traditional housekeeping genes. The selection of most suitable reference genes depends on the experimental conditions, and is tissue and cultivar-specific. Further, to attain accuracy in the results more than one reference genes are necessary for normalization.
Towards a Characterization of Behavior-Disease Models

The last decade saw the advent of increasingly realistic epidemic models that leverage on the availability of highly detailed census and human mobility data. Data-driven models aim at a granularity down to the level of households or single individuals. However, relatively little systematic work has been done to provide coupled behavior-disease models able to close the feedback loop between behavioral changes triggered in the population by an individual's perception of the disease spread and the actual disease spread itself. While models lacking this coupling can be extremely successful in mild epidemics, they obviously will be of limited use in situations where social disruption or behavioral alterations are induced in the population by knowledge of the disease. Here we propose a characterization of a set of prototypical mechanisms for self-initiated social distancing induced by local and non-local prevalence-based information available to individuals in the population. We characterize the effects of these mechanisms in the framework of a compartmental scheme that enlarges the basic SIR model by considering separate behavioral classes within the population. The transition of individuals in/out of behavioral classes is coupled with the spreading of the disease and provides a rich phase space with multiple epidemic peaks and tipping points. The class of models presented here can be used in the case of data-driven computational approaches to analyze scenarios of social adaptation and behavioral change.
Your Body of Water: A Display that Visualizes Aesthetic Heart Rate Data from a 3D Camera

We present the design and implementation of Your Body of Water, a display that wirelessly gathers heart rate data using a 3D camera and then visualizes the viewer's heart rate as water. As heart rate goes up the water gets livelier (with larger and faster waves) and as heart rate goes down the water gets calmer. The purpose of the display is to use aesthetic biofeedback data to help participants reflect on their felt bodily experience. The device went through system critique using somaesthetic appreciation design heuristics, and we describe the design themes that arose from those critiques.
What Maintains the Central North Pacific Genetic Discontinuity in Pacific Herring?

Pacific herring show an abrupt genetic discontinuity in the central North Pacific that represents secondary contact between refuge populations previously isolated during Pleistocene glaciations. Paradoxically, high levels of gene flow produce genetic homogeneity among ocean-type populations within each group. Here, we surveyed variability in mtDNA control-region sequences (463 bp) and nine microsatellite loci in Pacific herring from sites across the North Pacific to further explore the nature of the genetic discontinuity around the Alaska Peninsula. Consistent with previous studies, little divergence (ΦST = 0.011) was detected between ocean-type populations of Pacific herring in the North West Pacific, except for a population in the Yellow Sea (ΦST = 0.065). A moderate reduction in genetic diversity for both mtDNA and microsatellites in the Yellow Sea likely reflects founder effects during the last colonization of this sea. Reciprocal monophyly between divergent mtDNA lineages (ΦST = 0.391) across the Alaska Peninsula defines the discontinuity across the North Pacific. However, microsatellites did not show a strong break, as eastern Bering Sea (EBS) herring were more closely related to NE Pacific than to NW Pacific herring. This discordance between mtDNA and microsatellites may be due to microsatellite allelic convergence or to sex-biased dispersal across the secondary contact zone. The sharp discontinuity between Pacific herring populations may be maintained by high-density blocking, competitive exclusion or hybrid inferiority.
Association of Maternal Preeclampsia With Infant Risk of Premature Birth and Retinopathy of Prematurity

Importance Studies report conflicting associations between preeclampsia and retinopathy of prematurity (ROP). This study provides explanations for the discrepancies to clarify the relationship between preeclampsia and ROP. Objective To evaluate the association of maternal preeclampsia and risk of ROP among infants in an unrestricted birth cohort and a restricted subcohort of preterm, very low birth weight (P-VLBW) infants. Design, Setting, and Participants A retrospective review of 290 992 live births within the Intermountain Healthcare System in Utah from January 1, 2001, through December 31, 2010, was performed. Generalized estimating equations for logistic regressions with covariate adjustment were applied to relate ROP to preeclampsia among the full cohort and in a subcohort of P-VLBW infants born at younger than 31 weeks’ gestation and weighing less than 1500 g. Main Outcomes and Measures The occurrence of ROP was related to maternal preeclampsia in the full cohort and in a subcohort of P-VLBW infants. Results In the full cohort, 51% of the infants were male and the mean (SD) gestational age was 38.38 (1.87) weeks. In the P-VLBW cohort, 55% were male and the mean (SD) gestational age was 26.87 (2.40) weeks. In the full cohort, preeclampsia was associated with an increased risk of all ROP (adjusted odds ratio [aOR], 2.46; 95% CI, 2.17–2.79; P < .001), severe ROP (aOR, 5.21; 95% CI, 3.44–7.91; P < .001), infant death (aOR, 1.66; 95% CI, 1.16–2.38; P = .006), and giving birth to a P-VLBW infant (aOR, 7.74; 95% CI, 6.92–8.67; P < .001). In the P-VLBW subcohort, preeclampsia was inversely associated with the development of all ROP (aOR, 0.79; 95% CI, 0.68–0.92; P = .003), severe ROP (aOR, 0.62; 95% CI, 0.36–1.06; P = .08), and infant death (aOR, 0.19; 95% CI, 0.11-0.32; P < .001). Conclusions and Relevance Preeclampsia was associated with an increased risk of developing ROP among an unrestricted cohort but with a reduced risk of ROP among a restricted subcohort of P-VLBW infants. Although the conflicting associations in the full and P-VLBW cohorts may reflect true differences, the association of a reduced risk of ROP among the P-VLBW subcohort also may reflect biases from restricting the cohort to prematurity, because prematurity is an outcome of preeclampsia.
Agriculture Sustainability: A California Agribusiness Students’ Perspective

Agribusiness managers as the major players in the agricultural industry greatly determine agribusiness practicesand affectperception about agricultural sustainability. This study develops a framework to analyze howagribusiness students, the future agribusiness managers, in California view sustainable agriculture. Aneducational program was created and implemented to raise awareness and educate students about agriculturalsustainability. Pre-and post-surveys were administered to collect relevant data and a conditional logit model wasestimated. Our main results suggest that: 1) the educational program is more influential on the ratings of theexternal social and environmental sustainability than on economic and internal social sustainability; 2)participating in the educational program helped future managers realize the importance of obtaining stableincome to achieve economic sustainability; and 3) water quality and farm continuity are important attributesinfarm environmental and internal social sustainability. Given the lack of consensus on how to defineagricultural sustainability, this study provides insightful information to help understand how future agriculturemanagers perceive sustainable farming.
Low Pitched Voices Are Perceived as Masculine and Attractive but Do They Predict Semen Quality in Men?

Women find masculinity in men's faces, bodies, and voices attractive, and women's preferences for men's masculine features are thought to be biological adaptations for finding a high quality mate. Fertility is an important aspect of mate quality. Here we test the phenotype-linked fertility hypothesis, which proposes that male secondary sexual characters are positively related to semen quality, allowing females to obtain direct benefits from mate choice. Specifically, we examined women's preferences for men's voice pitch, and its relationship with men's semen quality. Consistent with previous voice research, women judged lower pitched voices as more masculine and more attractive. However men with lower pitched voices did not have better semen quality. On the contrary, men whose voices were rated as more attractive tended to have lower concentrations of sperm in their ejaculate. These data are more consistent with a trade off between sperm production and male investment in competing for and attracting females, than with the phenotype-linked fertility hypothesis.
22-GHz-Band Oscillator Using Integrated H-Shape Defected Ground Structure Resonator in 0.18- $\mu \text{m}$ CMOS Technology

A novel 22-GHz-band oscillator using an integrated defected ground structure (DGS) resonator is presented for quasi-millimeter waveband applications. The DGS is etched on the first metal layer (M1) below a 50-<inline-formula> <tex-math notation="LaTeX">$\Omega $ </tex-math></inline-formula> microstrip line on the top metal layer (M6) of 0.18-<inline-formula> <tex-math notation="LaTeX">$\mu \text{m}$ </tex-math></inline-formula> one-poly six-metal (1P6M) complementary metal-oxide-semiconductor (CMOS) technology. The proposed oscillator is fabricated using 0.18-<inline-formula> <tex-math notation="LaTeX">$\mu \text{m}$ </tex-math></inline-formula> CMOS technology, and the measured carrier frequency and phase noise are 22.88 GHz and −129.21 dBc/Hz (−108.05 dBc/Hz) at 10-MHz (1 MHz) offset frequency, respectively. The power dissipation is 6 mW that results in a figure of merit to be −188.8 dB. As the DGS resonator could be designed at any high frequency, it may give an alternative design approach of high performance voltage controlled oscillator and frequency synthesizers at K-band and beyond, thus alleviates the problem of self-resonance that a spiral inductor usually encounters at higher frequency.
Crestal Bone Level Around Tissue-Level Implants Restored with Platform Matching and Bone-Level Implants Restored with Platform Switching: A 5-Year Randomized Controlled Trial.

PURPOSE The aim of this randomized clinical trial with a 5-year follow-up was to assess the differences in radiographic levels of peri-implant bone crest between tissue-level implants restored with platform matching (control group) and bone-level implants restored with platform switching (test group) in the posterior region. MATERIALS AND METHODS To assess marginal bone level changes, periapical radiographs were taken at the moment of prosthesis delivery (baseline), at 1 year, and at 5 years after the definitive restoration. RESULTS One hundred subjects, partially edentulous in the posterior region, were selected for this study. There were 54 men and 46 women between the ages of 25 and 70 years (mean = 50.5 years). A total of 202 implants were assigned to both groups using a randomized procedure (100 implants in the control group and 102 in the test group). The mean marginal bone level (MBL) changes for tissue-level implants restored with platform matching were 0.26 ± 0.55 mm at baseline to 1 year, 0.34 ± 0.54 mm at 1 year to 5 years, and 0.61 ± 0.73 mm at baseline to 5 years. The mean MBL changes for bone-level implants restored with platform switching were -0.03 ± 0.74 mm at baseline to 1 year, -0.17 ± 0.67 mm at 1 year to 5 years, and -0.20 ± 0.75 mm at baseline to 5 years. The mean difference between the two groups was 0.31 mm at baseline to 1 year, 0.53 mm at 1 year to 5 years, and 0.85 mm at baseline to 5 years. There was a statistically significant difference in MBL (P < .001). Both implant systems showed good and similar survival rates (98% for tissue-level implants restored with platform matching and 96.1% for bone-level implants restored with platform switching). CONCLUSION In this randomized controlled trial, the following observations were made. Radiographic levels of peri-implant bone crest in tissue-level implants restored by platform matching were statistically significant in the three interval times. Meanwhile, MBL changes for bone-level implants restored with platform switching were not statistically significant in the different times studied. Nevertheless, the mean difference between the two groups was statistically significant.
Mesotherapy, definition, rationale and clinical role: a consensus report from the Italian Society of Mesotherapy.

OBJECTIVE Since its introduction in the 1950s, the use of mesotherapy has generated much interest among clinicians and patients. The Italian Society of Mesotherapy (SIM) brought together a panel of experts to review available evidence and to draw up a series of recommendations on the use of intradermal therapy (LIT) in clinical practice. CONSENSUS REPORT There was overwhelming agreement among Consensus Group members that, when used correctly, LIT is a valuable therapeutic option in the treatment of painful, loco-regional conditions. They also emphasised that the clinical efficacy of LIT has been demonstrated in the management of chronic venous lymphatic insufficiency, oedematous fibrosclerotic panniculopathy and facial skin aging. The experts were unanimous on the use of LIT in vaccination. Mesotherapy is not a substitute for other therapeutic options and should only be used when the patient has been fully informed of its advantages and limitations. Likewise the procedure should only be carried out by an experienced qualified physician. CONCLUSIONS Although there was widespread agreement among the Consensus Group on the place of LIT in several indications, the Authors reiterated the need for more large-scale clinical trials to determine the specific benefits and limitations in some areas of the application of intradermal therapy.
Hardware-assisted circumvention of self-hashing software tamper resistance

Self-hashing has been proposed as a technique for verifying software integrity. Appealing aspects of this approach to software tamper resistance include the promise of being able to verify the integrity of software independent of the external support environment, as well as the ability to integrate code protection mechanisms automatically. In this paper, we show that the rich functionality of most modern general-purpose processors (including UltraSparc, x86, PowerPC, AMD64, Alpha, and ARM) facilitate an automated, generic attack which defeats such self-hashing. We present a general description of the attack strategy and multiple attack implementations that exploit different processor features. Each of these implementations is generic in that it can defeat self-hashing employed by any user-space program on a single platform. Together, these implementations defeat self-hashing on most modern general-purpose processors. The generality and efficiency of our attack suggests that self-hashing is not a viable strategy for high-security tamper resistance on modern computer systems.
Specific Receptor Usage in Plasmodium falciparum Cytoadherence Is Associated with Disease Outcome

Our understanding of the basis of severe disease in malaria is incomplete. It is clear that pathology is in part related to the pro-inflammatory nature of the host response but a number of other factors are also thought to be involved, including the interaction between infected erythrocytes and endothelium. This is a complex system involving several host receptors and a major parasite-derived variant antigen (PfEMP1) expressed on the surface of the infected erythrocyte membrane. Previous studies have suggested a role for ICAM-1 in the pathology of cerebral malaria, although these have been inconclusive. In this study we have examined the cytoadherence patterns of 101 patient isolates from varying clinical syndromes to CD36 and ICAM-1, and have used variant ICAM-1 proteins to further characterise this adhesive phenotype. Our results show that increased binding to CD36 is associated with uncomplicated malaria while ICAM-1 adhesion is raised in parasites from cerebral malaria cases.