Miracle-dz/UniFAR-FTUs huggingface dataset:
L’impact du handicap sur les trajectoires d’emploi : une comparaison public-privé

In this study, we use panel data built from the “Sante et itineraire professionnel” (Sip) (“Health and Labor Market Histories”) survey conducted in France in 2006-2007, we investigate whether handicaps have a significant impact on individuals’ performance in the labour market depending on the sector of employment, distinguishing the effects of the handicap’s length (transitory or permanent) and origin (accident or disease). We use the difference in differences (DiD) methodology with exact dynamic matching in order to control for both observable and unobservable correlated heterogeneity). We also control for lagged endogenous variables. We find that, whatever the origin of handicap, the public sector seems to fully protect people against losing one’s job in the case of transitory handicap (less one year) whereas it strongly decreases the likelihood of losing one’s job in the case of permanent handicap. Nevertheless, in the private sector, handicap has a negative impact whose magnitude varies according to the persistence and the origin of handicap, as well as gender.
Kank regulates RhoA-dependent formation of actin stress fibers and cell migration via 14-3-3 in PI3K–Akt signaling

Phosphoinositide-3 kinase (PI3K)/Akt signaling is activated by growth factors such as insulin and epidermal growth factor (EGF) and regulates several functions such as cell cycling, apoptosis, cell growth, and cell migration. Here, we find that Kank is an Akt substrate located downstream of PI3K and a 14-3-3–binding protein. The interaction between Kank and 14-3-3 is regulated by insulin and EGF and is mediated through phosphorylation of Kank by Akt. In NIH3T3 cells expressing Kank, the amount of actin stress fibers is reduced, and the coexpression of 14-3-3 disrupted this effect. Kank also inhibits insulin-induced cell migration via 14-3-3 binding. Furthermore, Kank inhibits insulin and active Akt-dependent activation of RhoA through binding to 14-3-3. Based on these findings, we hypothesize that Kank negatively regulates the formation of actin stress fibers and cell migration through the inhibition of RhoA activity, which is controlled by binding of Kank to 14-3-3 in PI3K–Akt signaling.
Motor cortex stimulation enhances motor recovery and reduces peri-infarct dysfunction following ischemic insult

Abstract Recovery of motor function following stroke is believed to be supported, at least in part, by functional compensation involving residual neural tissue. The present study used a rodent model of focal ischemia and intracortical microstimulation (ICMS) to examine the behavioral and physiological effects of cortical stimulation in combination with motor rehabilitation. Adult rats were trained to criterion on a single pellet reaching task before ICMS was used to derive maps of movement representations within forelimb motor cortex contralateral to the trained paw. All animals then received a focal ischemic infarct within the motor map. A cortical surface electrode was implanted over the motor cortex. Low levels of electrical stimulation were applied during rehabilitative training on the same reaching task for 10 days and ICMS used to derive a second motor map. Results showed that both monopolar and bipolar cortical stimulation significantly enhanced motor recovery and increased the area of cortex from which microstimulation movements could be evoked. The results demonstrate the behavioral and neurophysiological benefits of cortical stimulation in combination with rehabilitation for recovery from stroke.
Design and implementation of a supervisory system for wind turines inverters

This paper describes the implementation of a supervisory system for wind turbine inverters, that incorporates into the frequency inverter the characteristics of the relays necessary for microgeneration. As a result, the inverter added value is increased, as external protective relays are not needed. A diagram depicting the possible inverter operating status and respective control actions is shown. The methods utilized to implement the functionalities related to inverter protection are also described. To validate the proposed supervisory system, experimental results are presented and compared to Grid Code requirements.
Modeling the relationships between subdimensions of environmental literacy

Abstract The aim of this study is to demonstrate the relationships between subdimensions of environmental literacy using Structural Equation Modeling (SEM). The study was conducted by the analysis of students' answers to questionnaires data using SEM. Initially, Kaiser-Meyer-Olkin and Bartlett's tests were done to test appropriateness of subdimensions to factor analysis. Exploratory factor analysis was done for the subdimensions that were seen to be suitable for factor analysis and then structural model was tested. At the end of the SEM test, it was found that there are positive and high relations between knowledge, behavior, attitude, and tendency.
Surprise as a conceptual category

In this paper, I examine the concept of surprise from a cognitive linguistic perspective. As previous studies indicate, surprise is a not-quite-prototypical emotion category. My focus will be on the structure and content of surprise as an emotion category, as this can be revealed on the basis of the language speakers of English use to talk about it. As regards methodology, I will follow my earlier work and employ a “lexical approach” to emotion concepts (see, e.g., Kovecses, 1986, 1990, 2000) to explore the language-based folk model of surprise in English. I will investigate the conceptual metaphors and metonymies associated with surprise and will propose a cognitive model for the emotion. It is hoped that this methodology enables us to see why surprise is not a prototypical emotion concept on a par with, for example, anger or fear.
Protective effects of α-tocopherol against oxidative stress related to nephrotoxicity by monosodium glutamate in rats

Context: Chronic oral intake of high doses of monosodium glutamate (MSG) could be harmful to tissues and organs. Oxidative stress enhances membrane damage by lipid peroxidation and alterations of antioxidant enzymes, which affects the functional activity of organs. Antioxidant vitamins have the capacity to regulate the oxidative stress related functional and pathological processes. Objective: In this study, the protective role of α-tocopherol against MSG-induced nephrotoxicity was analyzed. Materials and methods: MSG (4 g/kg) was given orally to female wistar rats for a period of 180 days. Renal function parameters (urea, uric acid, and creatinine), lipid peroxidation markers (malondialdehyde and conjugated dienes), antioxidant system (superoxide dismutase, catalase, glutathione peroxidase, glutathione transferase, and reduced glutathione), and histopathology were investigated. All tests were done in rats treated with MSG and at two different doses of α-tocopherol (100 and 200 mg/kg). Results: Oral exposure of MSG significantly increased renal function markers, lipid peroxidation byproducts, and altered antioxidant system. Moreover, the kidney showed congested glomeruli, tubular swelling, capillary congestion and microhemorrhages in stromal areas of the tubules. Co-administration of MSG and α-tocopherol (200 mg/kg) significantly reduced the oxidative damage compared with MSG-treated group and also restored the normal renal function. Discussion: The results indicated that oxidative stress was involved in MSG-induced functional and pathological changes in the kidney. α-tocopherol modulates the functional disorder and maintains the normal architecture of renal tissue by reducing oxidative stress. Conclusion: The α-tocopherol may be a potent protective agent in combating MSG-induced renal toxicity.
Evidence-Based Clinical Practice Guidelines Initial Diagnosis of Lung Cancer : ACCP

2007;132;131-148 Chest M. Patricia Rivera and Atul C. Mehta (2nd Edition) Evidence-Based Clinical Practice Guidelines Initial Diagnosis of Lung Cancer: ACCP http://chestjournal.org/cgi/content/abstract/132/3_suppl/131S and services can be found online on the World Wide Web at: The online version of this article, along with updated information ). ISSN: 0012-3692. http://www.chestjournal.org/misc/reprints.shtml ( of the copyright holder may be reproduced or distributed without the prior written permission Northbrook IL 60062. All rights reserved. No part of this article or PDF by the American College of Chest Physicians, 3300 Dundee Road, 2007 Physicians. It has been published monthly since 1935. Copyright CHEST is the official journal of the American College of Chest
Batf3 Deficiency Reveals a Critical Role for CD8α+ Dendritic Cells in Cytotoxic T Cell Immunity

Although in vitro observations suggest that cross-presentation of antigens is mediated primarily by CD8α+ dendritic cells, in vivo analysis has been hampered by the lack of systems that selectively eliminate this cell lineage. We show that deletion of the transcription factor Batf3 ablated development of CD8α+ dendritic cells, allowing us to examine their role in immunity in vivo. Dendritic cells from Batf3–/– mice were defective in cross-presentation, and Batf3–/– mice lacked virus-specific CD8+ T cell responses to West Nile virus. Importantly, rejection of highly immunogenic syngeneic tumors was impaired in Batf3–/– mice. These results suggest an important role for CD8α+ dendritic cells and cross-presentation in responses to viruses and in tumor rejection.
Molecular Phylogeny of Sesiidae (Lepidoptera) Inferred From Mitochondrial DNA Sequences

Abstract Partial DNA sequence data from the mitochondrial DNA (mtDNA) cytochrome oxidase I and II genes were used to construct a molecular phylogeny based on representative species from 10 of the 20 genera of Sesiidae. Maximum likelihood, maximum parsimony, and Bayesian analysis were utilized. Sequencing of a 606-base pair region of the mtDNA cytochrome oxidase I (COI), tRNA leucine, and COII gene revealed 271 polymorphic sites among 20 species. Genetic variation ranged from 0.8 to 21.2% among species. Maximum parsimony, maximum likelihood, and Bayesian analysis do not support the recent synonmy of Synansphecia as Pyropteran. Maximum parsimony and maximum likelihood support the recent divergence of Synanthedon pamphyla from Synanthedon culciformis, which are almost identical morphologicaly. Maximum likelihood, parsimony, and Bayesian analysis do not support the inclusion of Melittia cucurbitae in the Sesiinae subfamily. All analysis support Synanthedon included in the Sesiinae subfamily. All analysis also give support for Vitacea and Paranthrene forming the subfamily Paranthrenini. This is the first attempt to resolve relationships within Sesiidae with molecular data. Sesiidae are a divergent order of Lepidoptera in which many relationships should be examined more closely. Future studies should investigate nucleur markers to further support relationships supported by molecular data.
Mix Queues Approach for Indoor Network Traffic Modelling

As a result of increasing international air traffic, airports are one of the most complicated built environments. Airport terminals will increasingly require ubiquitous systems with high levels of computational power to provide the necessary intelligent automation, high quality services to passengers and stringent levels of safety and security that are as unobtrusive as possible. These requirements involve mobile appliances, and hence, an advanced telecommunication network that can handle the teletraffic load reliably and efficiently. In this paper we propose a mixed of series queues to model the airport network. The model cannot result in closed form solution to the steady state probability of the network. Instead, the proposed model divides the whole network into stages of separately defined queues which can be dealt with independently. Important data such as number of passengers in the nodes and the time spent in the queues can be obtained by considering each stage separately. The model is used to find the teletraffic distribution over the network in different times.
Pilot dose‐finding and safety study of bivalirudin in infants <6 months of age with thrombosis

Summary. Background: Thrombosis is not uncommon in children with serious medical conditions. Unfractionated heparin, the most commonly used anticoagulant in the acute management of thrombosis, has significant pharmacologic limitations, especially in infants. Newer anticoagulants have improved properties relative to heparin, and this may enhance the outcome in children.Objective: To determine dosing, and to assess the safety and efficacy of bivairudin for infants with thrombosis.Methods: Infants <6 months old were chosen for this pilot study as they may most benefit from a direct thrombin inhibitor because of their physiologically low antithrombin levels. This was an open label, dose‐finding and safety study. Patients received one of three bolus doses and one of two initial infusion doses with subsequent dosing adjusted utilizing the activated partial thromboplastin time. Safety was assessed by specific bleeding endpoints. Efficacy was determined by reassessing the initial imaging study at 48–72 h and by measurement of molecular markers of thrombin generation.Results: Sixteen patients completed the study. All three bolus doses resulted in therapeutic anticoagulation, as did both initial infusion doses. A dose–response effect was noted for the continuous infusion but not the bolus dosing. Two patients met the study criteria for major bleeding, both with gross hematuria, which resolved with a reduction in the bivalirudin infusion rate. In terms of efficacy, 37.5% of patients had complete or partial resolution of their thrombosis by 48–72 h. There was a significant decrease in all three molecular markers of thrombin generation.Conclusion: This study demonstrates the potential utility of bivalirudin in the pediatric population.
Statistical pre-filtering for OFDM systems with multiple transmit antennas

The incorporation of orthogonal frequency division multiplexing (OFDM) with space-time/frequency coding is a robust and effective method to achieve transmit diversity gain and also suppress both multipath fading and inter-symbol interference for broadband wireless transmissions. This paper is concerned with downlink performance improvement using multiple transmit antennas for OFDM systems with large delay spread. We propose a delay spread reduction method using space frequency block coding and statistical pre-filtering, which combines signal pre-alignment and multiple transmit beamformers, designed with the statistical knowledge of downlink channel state information. The proposed method transforms a large delay spread channel into multiple channels with small delay spread, thus not only shortening the required cyclic prefix length, but also maintaining path diversity by the use of space-frequency coding. By computer simulations we evaluated the effectiveness of the proposed method.
A practical application of behaviour modelling in ethorobotics

The main contribution of this paper is the detailed design of an ethorobotic test environment for simulating behaviour models, together with an implementation of an autonomous, creature-like behaviour model. The test environment is a robot which is, with the help of the implemented model, capable of detecting information about its environment and, by using this information, of modelling emotions. The emotional state of the robot directly affects the parameters of its movements. Our evaluations show that the presented robot can explore its surroundings, avoid obstacles and express its emotional state.
On Dictionary-Based Fault Location in Digital Logic Circuits

In this work, fault location based on a fault dictionary is considered at the chip level. To justify the use of a precomputed dictionary in terms of computation time, the computational effort invested in computing a dictionary is first analyzed. The number of circuit diagnoses that need to be performed dynamically, without the use of precomputed knowledge, before the overall diagnosis effort exceeds the effort of computing a dictionary, is studied. Experimental results on ISCAS-85 circuits show that for relatively small numbers of diagnoses, a precomputed dictionary is more efficient than dynamic diagnosis. Next, a method to derive small dictionaries without losing resolution of modeled faults is proposed, based on extended pass/fail analysis. The same procedure is applicable for selecting internal observation points to increase the resolution of the test set. Methods to compact the resulting dictionary further, using compaction techniques generally applied to fault detection, are then described. Experimental results are presented to demonstrate the effectiveness of the proposed methods.
Reconstruction of Oryza sativa indica Genome Scale Metabolic Model and Its Responses to Varying RuBisCO Activity, Light Intensity, and Enzymatic Cost Conditions

To combat decrease in rice productivity under different stresses, an understanding of rice metabolism is needed. Though there are different genome scale metabolic models (GSMs) of Oryza sativa japonica, no GSM with gene-protein-reaction association exist for Oryza sativa indica. Here, we report a GSM, OSI1136 of O.s. indica, which includes 3602 genes and 1136 metabolic reactions and transporters distributed across the cytosol, mitochondrion, peroxisome, and chloroplast compartments. Flux balance analysis of the model showed that for varying RuBisCO activity (Vc/Vo) (i) the activity of the chloroplastic malate valve increases to transport reducing equivalents out of the chloroplast under increased photorespiratory conditions and (ii) glyceraldehyde-3-phosphate dehydrogenase and phosphoglycerate kinase can act as source of cytosolic ATP under decreased photorespiration. Under increasing light conditions we observed metabolic flexibility, involving photorespiration, chloroplastic triose phosphate and the dicarboxylate transporters of the chloroplast and mitochondrion for redox and ATP exchanges across the intracellular compartments. Simulations under different enzymatic cost conditions revealed (i) participation of peroxisomal glutathione-ascorbate cycle in photorespiratory H2O2 metabolism (ii) different modes of the chloroplastic triose phosphate transporters and malate valve, and (iii) two possible modes of chloroplastic Glu–Gln transporter which were related with the activity of chloroplastic and cytosolic isoforms of glutamine synthetase. Altogether, our results provide new insights into plant metabolism.
Executive Function and Nitric Oxide in Mild-Moderate Traumatic Brain Injury

Incidence of Traumatic Brain Injury (TBI) mostly in mild - moderate TBI, increasing the brain disorders due to primary insults and secondary insults by the multiple pathomechanisms. Brain damaging process manifested in brain function disorders primarily the cognitive function, included the executive function disorders. Executive function is a wide description about processes involving in cognitive areas and behavioral control. The aim of this study is to compare the executive function in mild-moderate TBI to the normal population. This is a comparative study design conducted in Kandou General Hospital, Manado, North Sulawesi in September - November 2014 involving of 19 cases and 37 control subjects. The executive function examinations that significanly associated to NO levels in mild-moderate TBI are MoCA, TMT-A and TMT-B (p < 0.05). The results provides evidence for a prevention againts the risk for neurobehavior disorders in mild-moderate TBI.
Flagship: a parallel architecture for declarative programming

The Flagship project aims to produce a computing technology based on the declarative style of programming. A major component of that technology is the design for a parallel machine that can efficiently utilize the implicit parallelism in declarative programs. The computational models that expose this implicit parallelism are described, and an architecture designed to use it is outlined. The operational issues, such as dynamic load balancing, that arise in such a system are discussed, and the mechanisms being used to evaluate the architecture are described. <<ETX>>
U.S. Marines’ Attitudes Regarding Cross-Cultural Capabilities in Military Operations

Cross-cultural competence not only emphasizes building specific skill sets such as language proficiency or negotiation skills, but also on changing the military's attitudes to other cultures by emphasizing the value and importance of cultural skills for successful military operations. In contrast to developing cultural skills, the task of shifting cultural attitudes is a far more complex process. Using empirical data from a survey of 2,406 Marines, this paper seeks to identify some of the social, demographic and experiential factors that influence military service members' attitudes to the value of culture in military operations. The authors found that of the demographic factors tested, only education and commissioning were positively related to attitudes. The greatest predictors were experiential factors: language skills, a multicultural background, travel experience and frequency of interaction with the local population during a previous deployment. Deployment alone was not a predictor. Cultural training was not related to attitudes, although satisfaction with the cultural training was a predictor of positive attitudes.
Bare hand interaction in tabletop augmented reality

Augmented Reality (AR) techniques have been applied to many application areas; however, there is still research that needs to be conducted on the best way to interact with AR content. Since hands are our main means of interaction with objects in real life, it would be natural for AR interfaces to allow free hand interaction with virtual objects. We present a system that tracks the 2D position of the user's hands on a tabletop surface, allowing the user to move, rotate and resize the virtual objects over this surface. Our implementation is based on a computer vision tracking system that processes the video stream of a single usb camera.
Host-Microbe Interactions and Defense Mechanisms in the Development of Amoebic Liver Abscesses

SUMMARY Amoebiasis by Entamoeba histolytica is a major public health problem in developing countries and leads to several thousand deaths per year. The parasite invades the intestine (provoking diarrhea and dysentery) and the liver, where it forms abscesses (amoebic liver abscesses [ALAs]). The liver is the organ responsible for filtering blood coming from the intestinal tract, a task that implies a particular structure and immune features. Amoebae use the portal route and break through the sinusoidal endothelial barrier to reach the hepatic parenchyma. When faced with systemic and cell-mediated defenses, trophozoites adapt to their new environment and modulate host responses, leading to parasite survival and the formation of inflammatory foci. Cytopathogenic effects and the onset of inflammation may be caused by diffusible products originating from parasites and/or immune cells either by their secretion or by their release after cell death. Liver infection thus results from the interplay between E. histolytica and hepatic cells. Despite its importance in terms of public health burden, the lack of integrated data on ALA genesis means that we have only an incomplete description of the initiation and development of hepatic amoebiasis. Here, we review the main steps of ALA development as well as the responses triggered in both the host and the parasite. Transcriptome studies highlighted parasite factors involved in adherence to human cells, cytopathogenic effects, and adaptative and stress responses. An understanding of their role in ALA development will help to unravel the host-pathogen interactions and their evolution throughout the infection.