Miracle-dz/UniFAR-FTUs huggingface dataset:
Incremental Elliptical Boundary Estimation for Anomaly Detection in Wireless Sensor Networks

Wireless Sensor Networks (WSNs) provide a low cost option for gathering spatially dense data from different environments. However, WSNs have limited energy resources that hinder the dissemination of the raw data over the network to a central location. This has stimulated research into efficient data mining approaches, which can exploit the restricted computational capabilities of the sensors to model their normal behavior. Having a normal model of the network, sensors can then forward anomalous measurements to the base station. Most of the current data modeling approaches proposed for WSNs require a fixed offline training period and use batch training in contrast to the real streaming nature of data in these networks. In addition they usually work in stationary environments. In this paper we present an efficient online model construction algorithm that captures the normal behavior of the system. Our model is capable of tracking changes in the data distribution in the monitored environment. We illustrate the proposed algorithm with numerical results on both real-life and simulated data sets, which demonstrate the efficiency and accuracy of our approach compared to existing methods.
Numerical Simulation of Transport Phenomena for Laser Full Penetration Welding

In laser full penetration welding process, full penetration hole(FPH) is formed as a result of force balance between the vapor pressure and the surface tension of the surrounding molten metal. In this work, a three-dimensional numerical model based on a conserved-mass level-set method is developed to simulate the transport phenomena during laser full penetration welding process, including full penetration keyhole dynamics. Ray trancing model is applied to simulate multi-reflection phenomena in the keyhole wall. The ghost fluid method and continuum method are used to deal with liquid/vapor interface and solid/liquid interface. The effects of processing parameters including laser power and scanning speed on the resultant full penetration hole diameter, laser energy distribution and energy absorption efficiency are studied. The model is validated against experimental results. The diameter of full penetration hole calculated by the simulation model agrees well with the coaxial images captured during laser welding of thin stainless steel plates. Numerical simulation results show that increase of laser power and decrease of welding speed can enlarge the full penetration hole, which decreases laser energy efficiency.
Human actions recognition using Fuzzy PCA and discriminative hidden model

As a temporal classification problem, visual-based human actions recognition is an important component for some potential applications. In this paper, we combine Fuzzy Principle Component Analysis(Fuzzy PCA) and hidden Conditional Random Fields(HCRFs) to achieve a viewpoint insensitive human action recognition. Fuzzy PCA is used to reduce the dimension of the silhouette image features to obtain the compact representation of action space. HCRFs is applied to model the human actions from different actors and different viewpoints. This method can relax the independence assumption of the generative model. Experiment results on a public dataset demonstrate the effectiveness and robustness of our method.
Unilateral Lesion of Dopamine Neurons Induces Grooming Asymmetry in the Mouse

Grooming behaviour is the most common innate behaviour in animals. In rodents, it consists of sequences of movements organized in four phases, executed symmetrically on both sides of the animal and creating a syntactic chain of behavioural events. The grooming syntax can be altered by stress and novelty, as well as by several mutations and brain lesions. Grooming behaviour is known to be affected by alterations of the dopamine system, including dopamine receptor modulation, dopamine alteration in genetically modified animals, and after brain lesion. While a lot is known about the initiation and syntactic modifications of this refined sequence of movements, effects of unilateral lesion of dopamine neurons are unclear particularly regarding the symmetry of syntactic chains. In the present work we studied grooming in mice unilaterally lesioned in the medial forebrain bundle by 6-hydroxydopamine. We found a reduction in completion of grooming bouts, associated with reduction in number of transitions between grooming phases. The data also revealed the development of asymmetry in grooming behaviour, with reduced tendency to groom the contralateral side to the lesion. Symmetry was recovered following treatment with L-DOPA. Thus, the present work shows that unilateral lesion of dopamine neurons reduces self-grooming behaviour by affecting duration and numbers of events. It produces premature discontinuation of grooming chains but the sequence syntax remains correct. This deficient grooming could be considered as an intrinsic symptom of Parkinson’s disease in animal models and could present some similarities with abnormalities of motor movement sequencing seen in patients. Our study also suggests grooming analysis as an additional method to screen parkinsonism in animal models.
The Economics of Private Equity Funds

This article analyzes the economics of the private equity industry using a novel model and dataset. We obtain data from a large investor in private equity funds, with detailed records on 238 funds raised between 1993 and 2006. We build a model to estimate the expected revenue to managers as a function of their investor contracts, and we test how this estimated revenue varies across the characteristics of our sample funds. Among our sample funds, about two-thirds of expected revenue comes from fixed-revenue components that are not sensitive to performance. We find sharp differences between venture capital (VC) and buyout (BO) funds. BO managers build on their prior experience by increasing the size of their funds faster than VC managers do. This leads to significantly higher revenue per partner and per professional in later BO funds. The results suggest that the BO business is more scalable than the VC business and that past success has a differential impact on the terms of their future funds. The Author 2010. Published by Oxford University Press on behalf of The Society for Financial Studies. All rights reserved. For Permissions, please e-mail: journals.permissions@oxfordjournals.org. , Oxford University Press. (This abstract was borrowed from another version of this item.)
A Sufficient Way of Mass Data Storage for Cloud Computing Based on Hashing Strategy

With the rapid development of information technology and Internet, the mass data storage of Internet is an urgent problem to be solved. Due to the insufficiency of single NameNode, a new improved data storage method based on HDFS was proposed. In this method, consistent hashing strategy was adopted for metadata allocation; NameNode clusters were built and BLT was used for management of NameNode mapping; log copy was used to achieve data security and consistency. Simulation results showed that the method can effectively improve read and write performance under ensuring metadata's security, consistency and fault tolerance.
A rank-aggregation approach to searching for optimal query-specific clusters

To improve the precision at the very top ranks of a document list presented in response to a query, researchers suggested to exploit information induced from clustering of documents highly ranked by some initial search. We propose a novel model for ranking such (query-specific) clusters by the presumed percentage of relevant documents that they contain. The model is based on (i) proposing a palette of "witness" cluster properties that purportedly correlate with this percentage, (ii) devising concrete quantitative measures for these properties, and (iii) ordering the clusters via aggregation of rankings induced by these individual measures. Empirical evaluation shows that our model is consistently more effective than previously suggested methods in detecting clusters containing a high relevant-document percentage. Furthermore, the precision-at-top-ranks performance of this model transcends that of standard document-based retrieval, and competes with that of a state-of-the-art document-based retrieval approach.
c-Jun NH2-Terminal Kinase Activation Contributes to Hypoxia-Inducible Factor 1α–Dependent P-Glycoprotein Expression in Hypoxia

We previously have shown that hypoxia increases the expression of P-glycoprotein, which in turn increases tumor cell capacity to actively extrude chemotherapeutic agents and may contribute to tumor drug resistance. This event is mediated through the hypoxia-inducible factor (HIF-1). Here, we investigated the role of the stress-activated protein kinase c-Jun NH2-terminal kinase (JNK) in the signaling mechanisms underlying these events. Hypoxia activates JNK activity in vitro and in vivo. Overexpression of mitogen-activated protein kinase (MAPK) kinase kinase (MEKK-1), which preferentially activates JNK, mimics, in a nonadditive way, hypoxia-induced activity of the MDR1 promoter and expression of MDR1 mRNA and P-glycoprotein. Furthermore, the JNK inhibitor SP600125 selectively and specifically inhibits hypoxia- and MEKK-1–induced MDR1 promoter activity in a dose-dependent manner. JNK inhibition also reversed hypoxia- and MEKK-1–induced activity of an HIF-1–dependent reporter gene. MEKK-1–induced MDR1 expression depends on a functional HIF-1 binding site (hypoxia-responsive element). Hypoxia- but not cobalt chloride–dependent HIF-1–DNA binding and transcriptional activation was inhibited by SP600125, indicating that hypoxia-induced signaling to HIF-1 depends on JNK activation. Because it has been reported that reactive oxygen species are increased in hypoxia and related to JNK activation, we investigated their role in signaling this response. Whereas exogenous addition of H2O2 was sufficient to activate JNK, reactive oxygen species scavengers were without effect on hypoxia-induced JNK or HIF-1 activation. Thus, hypoxia-elicited MDR1 expression, which depends on HIF-1 activation, depends at least in part on signaling via activation of JNK. Furthermore, these events are independent of the generation of reactive oxygen intermediates. Thus, JNK may represent a therapeutic target in the prevention of tumor resistance to chemotherapeutic treatment.
Labour Market Institutions and Wage Inequality

In this paper we investigate the importance of labor market institutions such as unemployment insurance, unions, firing regulation and minimum wages for the evolution of wage inequality across countries. We derive a simple log-linear equation of the wage differential as a function of the institutional parameters, total factor productivity, final good prices and relative skill supply. Our estimates for 11 OECD countries imply that labor market institutions can account for a large part of the change of wage inequality across countries after controlling for time and country effects.
YEE'S SCHEME FOR THE INTEGRATION OF MAXWELL'S EQUATION ON UNSTRUCTURED MESHES

The co-volume integration method, Yee's scheme, generalized to unstructured mesh is considered and compared with time domain finite element method (TDFE). In order to generate the meshes for which a good quality dual mesh is ensured, a new point placing method for the generation of meshes appropriate for the use of the co-volume method is proposed. Numerical examples are presented which demonstrate the consistency and performance of the co-volume method.
Studies of the basis of localization of influenza virus in ferret organ cultures.

Abstract The differing susceptibilities of ferret nasal mucosa and oesophagus to infection with influenza virus have been investigated. Evidence, obtained using organ cultures, suggested that virus was adsorbed with equal efficiency to both tissues. Electron microscopy showed virus directly adsorbed to the cilia and cell surfaces of the respiratory tissue. However, in contrast to nasal mucosa, virus adsorbed to oesophagus appeared to be mainly associated with an amorphous substance covering the epithelial cells and rarely in direct contact with cell membranes. Subsequently, virus penetrated the cells of the nasal mucosa and newly synthesized virus was recovered within 8 hr of infection. Virus apparently failed to penetrate the oesophagus and infective virus recovered probably merely represented residual inoculum.
Members, Isolates, and Liaisons: Meta-Analysis of Adolescents’ Network Positions and Their Smoking Behavior

Existing research finds that peer networks play an important role in adolescents’ smoking behaviors. To evaluate this research, meta-analysis was utilized to investigate the relationship between social positions (e.g., group members vs. isolates vs. liaisons) in friendship networks and smoking behaviors. The results (N = 5,067, k = 8) showed that adolescents from multiple countries who are isolated in friendship networks are more likely to report smoking behaviors than those with friends (members or liaisons). The results also show that these differential odds of smoking based on network position has decreased over the past 15 years.
Regulation of pri-miRNA processing by the hnRNP-like protein AtGRP7 in Arabidopsis

The hnRNP-like glycine-rich RNA-binding protein AtGRP7 regulates pre-mRNA splicing in Arabidopsis. Here we used small RNA-seq to show that AtGRP7 also affects the miRNA inventory. AtGRP7 overexpression caused a significant reduction in the level of 30 miRNAs and an increase for 14 miRNAs with a minimum log2 fold change of ±0.5. Overaccumulation of several pri-miRNAs including pri-miR398b, pri-miR398c, pri-miR172b, pri-miR159a and pri-miR390 at the expense of the mature miRNAs suggested that AtGRP7 affects pri-miRNA processing. Indeed, RNA immunoprecipitation revealed that AtGRP7 interacts with these pri-miRNAs in vivo. Mutation of an arginine in the RNA recognition motif abrogated in vivo binding and the effect on miRNA and pri-miRNA levels, indicating that AtGRP7 inhibits processing of these pri-miRNAs by direct binding. In contrast, pri-miRNAs of selected miRNAs that were elevated or not changed in response to high AtGRP7 levels were not bound in vivo. Reduced accumulation of miR390, an initiator of trans-acting small interfering RNA (ta-siRNA) formation, also led to lower TAS3 ta-siRNA levels and increased mRNA expression of the target AUXIN RESPONSE FACTOR4. Furthermore, AtGRP7 affected splicing of pri-miR172b and pri-miR162a. Thus, AtGRP7 is an hnRNP-like protein with a role in processing of pri-miRNAs in addition to its role in pre-mRNA splicing.
Heat-protective Ventilated Jackets: A Comparison of Humid and Dry Ventilating Air

A comparison has been made between humid and dry air for ventilating a heat-protective jacket. At sensible cooling capacities of 4·5 kcal. /min. and above, humid and dry air provided equal protection. At sensible cooling capacities of 4 kcal. /min. and above, the subject achieved thermal equilibrium within 65 min. with both humid and dry air, but below this value humid ventilating air is associated with elevated sweat rates and a failure to achieve thermal equilibrium within 65 minutes.
Histological Assessment of 526 Symptomatic Carotid Plaques in Relation to the Nature and Timing of Ischemic Symptoms: The Oxford Plaque Study

Background— Atherosclerotic plaque at the carotid bifurcation is often associated with transient ischemic attack (TIA) and ischemic stroke, but the mechanisms are not completely understood. Previous histological studies have been too small or insufficiently detailed to reliably determine the temporal course of features of plaque instability or to stratify analyses by the nature of presenting symptoms. Methods and Results— We performed the largest-ever histological study of symptomatic carotid plaques from consecutive patients (n=526) undergoing endarterectomy and related detailed reproducible histological assessments to the nature and timing of presenting symptoms. There was a high prevalence of many features of coronary-type plaque instability. Dense plaque inflammation (especially infiltration with macrophages) was the feature most strongly associated with both cap rupture (odds ratio 3.39, 95% confidence interval 2.31 to 4.98, P<0.001) and time since stroke (P=0.001). Strong negative associations with time since stroke were also seen for cap rupture (P=0.02), overall plaque inflammation (P=0.003), and “unstable plaque” (P=0.001). Although plaques removed ≤60 days after the most recent event were more unstable after a stroke than after a TIA, the instability persisted after a TIA, and plaques removed >180 days after most recent event were less unstable after a stroke than after a TIA (plaque inflammation: ≤60 days, odds ratio 2.33 [95% confidence interval 0.76 to 7.19]; >180 days, 0.36 [0.16 to 0.84]; P=0.008; unstable plaque: odds ratio 3.27 [95% confidence interval 0.93 to 11.50] versus 0.74 [0.33 to 1.69], P=0.05). Conclusions— Pathology of recently symptomatic carotid plaques is similar to that of culprit coronary plaques, with strong correlations between macrophage infiltration and plaque instability. The tendency for plaque inflammation and overall instability to persist with time after a TIA but to decrease with time after a stroke suggests that the nature of the underlying pathology may differ.
Combat‐related guilt mediates the relations between exposure to combat‐related abusive violence and psychiatric diagnoses

Background: This study examined the degree to which combat‐related guilt mediated the relations between exposure to combat‐related abusive violence and both Posttraumatic Stress Disorder (PTSD) and Major Depressive Disorder (MDD) in Vietnam Veterans. Methods: Secondary analyses were conducted on data collected from 1,323 male Vietnam Veterans as part of a larger, multisite study. Results: Results revealed that combat‐related guilt partially mediated the association between exposure to combat‐related abusive violence and PTSD, but completely mediated the association with MDD, with overall combat exposure held constant in the model. Follow‐up analyses showed that, when comparing those participants who actually participated in combat‐related abusive violence with those who only observed it, combat‐related guilt completely mediated the association between participation in abusive violence and both PTSD and MDD. Moreover, when comparing those participants who observed combat‐related abusive violence with those who had no exposure at all to it, combat‐related guilt completely mediated the association between observation of combat‐related abusive violence and MDD, but only partially mediated the association with PTSD. Conclusions: These findings suggest that guilt may be a mechanism through which abusive violence is related to PTSD and MDD among combat‐deployed Veterans. These findings also suggest the importance of assessing abusive‐violence related guilt among combat‐deployed Veterans and implementing relevant interventions for such guilt whenever indicated. Depression and Anxiety, 2010. © 2010 Wiley‐Liss, Inc.
Epigenetic Down-Regulation of CDKN1C/p57KIP2 in Pancreatic Ductal Neoplasms Identified by Gene Expression Profiling

Purpose: Intraductal papillary mucinous neoplasm (IPMN) of the pancreas is an increasingly identified precursor to infiltrating ductal adenocarcinoma. Although our knowledge of the clinical and pathologic features of IPMNs is increasing, the molecular mechanisms underlying these neoplasms remain poorly understood. Experimental Designs: To provide further insight into the molecular pathobiology of IPMNs, global expression profiling was done to determine genes that are inactivated/down-regulated in IPMNs using oligonucleotide microarrays (Affymetrix). Results: In total, 300 unique transcripts (217 known genes) were identified as highly underexpressed in 12 IPMNs (<10-fold lower and P < 0.05) compared with five normal pancreatic ductal epithelium samples obtained by laser capture microdissection. The differential expression of a selection of genes was confirmed using reverse-transcription PCR. One of the genes underexpressed at both the transcriptional and protein level in a significant proportion of IPMNs was the cyclin-dependent kinase inhibitor, CDKN1C/p57KIP2. CDKN1C expression was also decreased in many pancreatic cancer cell lines and was restored following treatment with a DNA methylation inhibitor (5-aza-2′-deoxycitidine) or, more potently, with a histone deacetylase inhibitor (trichostatin A). Partial methylation of the CDKN1C promoter CpG island was found in most, but not all, pancreatic cancer cell lines with reduced CDKN1C expression, and was also detectable in IPMNs. Furthermore, a subset of pancreatic cancers showed complete hypomethylation of LIT1, an imprinting control region important for the regulation of CDKN1C expression. Complete hypomethylation in these cancers was the result of deletion of the methylated LIT1 allele at 11p15.5 rather than loss of imprinting. Conclusions: These findings suggest that CDKN1C is commonly down-regulated in pancreatic ductal neoplasms through a combination of promoter hypermethylation, histone deacetylation, and loss of the maternal allele expressing CDKN1C.
Incremental HMM Alignment for MT System Combination

Inspired by the incremental TER alignment, we re-designed the Indirect HMM (IHMM) alignment, which is one of the best hypothesis alignment methods for conventional MT system combination, in an incremental manner. One crucial problem of incremental alignment is to align a hypothesis to a confusion network (CN). Our incremental IHMM alignment is implemented in three different ways: 1) treat CN spans as HMM states and define state transition as distortion over covered n-grams between two spans; 2) treat CN spans as HMM states and define state transition as distortion over words in component translations in the CN; and 3) use a consensus decoding algorithm over one hypothesis and multiple IHMMs, each of which corresponds to a component translation in the CN. All these three approaches of incremental alignment based on IHMM are shown to be superior to both incremental TER alignment and conventional IHMM alignment in the setting of the Chinese-to-English track of the 2008 NIST Open MT evaluation.