Miracle-dz/UniFAR-FTUs huggingface dataset:
Evaluation of the potential of dogs, cats and rats to spread classical swine fever virus

other antimicrobial agents against bacterial pathogens of swine from the United States, Canada and Denmark. Journal of Clinical Microbiology 33, 2435-2444 STEPHENS, C. P., GIBSON, J. A. & RICHARDSON, L. (1995) Antimicrobial susceptibility of Pasteurella multocida isolates from cases of pneumonia in slaughter swine from south-east Queensland. Australian Veterinary Journal 72, 156 WILSON, M. R. , TAKOV, R. , FRIENDSHIP, R. M. , MARTIN, S. W. , MCMILLAN, I. , HACKER, R. R. & SWAMINATHAN, S. (1986) Prevalence of respiratory diseases and their association with growth rate and space in randomly selected swine herds. Canadian Journal of Veterinary Research 50, 209-216
Uptake and Release of d‐Aspartate, GABA, and Glycine in Guinea Pig Brainstem Auditory Nuclei

Abstract: This study attempts to determine if the medial (MSO) and lateral superior olive (LSO), medial nucleus of the trapezoid body (MNTB), ventral nucleus of the lateral lemniscus (VNLL), and central nucleus of the inferior colliculus (ICc) contain glutamatergic synaptic endings. Micropunch and microdissection procedures provided fresh samples of these auditory nuclei for the measurement of the high‐affinity uptake and electrically evoked release of exogenous d‐[3H]ASP. The study also determined if the LSO and MSO contain glycinergic synaptic endings by measuring uptake and release of [14C]‐Gly in these nuclei, and whether the MNTB, VNLL, and ICc contain GABAergic endings by assessing the uptake and release of [14C]GABA in these structures. Several strategies optimized the evoked Ca2+‐dependent release of the labeled amino acids. These included the enhancement of high‐affinity uptake during loading of the markers into the tissues, inhibition of uptake during the subsequent measurement of release, and use of an electrical stimulus current that evoked maximal Ca2+‐dependent release. Each of these nuclei manifested the high‐affinity uptake and the evoked Ca2+‐dependent release of d‐[3H]Asp, suggesting the presence of synaptic endings that may use Glu or Asp as a transmitter. Similar findings suggest the presence of glycinergic synaptic endings in the LSO and MSO, and of GABAergic synaptic endings in the MNTB, VNLL, and ICc.
Deriving quantitative models for correlation clusters

Correlation clustering aims at grouping the data set into correlation clusters such that the objects in the same cluster exhibit a certain density and are all associated to a common arbitrarily oriented hyperplane of arbitrary dimensionality. Several algorithms for this task have been proposed recently. However, all algorithms only compute the partitioning of the data into clusters. This is only a first step in the pipeline of advanced data analysis and system modelling. The second (post-clustering) step of deriving a quantitative model for each correlation cluster has not been addressed so far. In this paper, we describe an original approach to handle this second step. We introduce a general method that can extract quantitative information on the linear dependencies within a correlation clustering. Our concepts are independent of the clustering model and can thus be applied as a post-processing step to any correlation clustering algorithm. Furthermore, we show how these quantitative models can be used to predict the probability distribution that an object is created by these models. Our broad experimental evaluation demonstrates the beneficial impact of our method on several applications of significant practical importance.
Sample isolation procedures

We first identified genes differentially expressed in rodent testis by comparing total testis, (TT; gonads whose tunica was removed by decapsulation) and isolated seminiferous tubules (TU; lacking the interstitial cells) to enriched populations of Sertoli cells (SE), spermatogonia (SG), pachytene spermatocytes (SC) and round spermatids (ST). Chondrocytes (CC) and vascular smooth muscle (SM) samples were included as controls because the human Sertoli cell and spermatogonia populations were not sufficiently pure for reliable analysis. To determine the number of conserved loci showing similar meiotic and post-meiotic expression across species, rodent samples were then compared to enriched human germ cells, tubules and total testis samples. To identify the subset of potentially testis-specific transcripts, somatic non-testicular control tissues were included in the analysis. Finally, among conserved, co-expressed and potentially testis-specific proteins, the group of factors known to be component of protein interaction networks was examined. All cell and tissue samples were pooled and processed in duplicate (see Supplementary Fig. 1).
Chymotryptic digestion of Tetrahymena ciliary dynein. II. Pathway of the degradation of 22S dynein heavy chains

As shown in the preceding paper (Toyoshima, Y. Y., 1987, J. Cell Biol., 105:887-895) three-headed Tetrahymena 22S dynein consists of three heavy chains (HCs) and is decomposed into two-headed (H) and one-headed (L) fragments by chymotryptic digestion. To accurately determine the presence of multiple ATPases and ultimately the location of various domains, it is necessary to determine the identity of each HC fragment relative to the original HCs in 22S dynein. The degradation pathway of each HC was determined by peptide mapping and immunoblotting. The three HCs (A alpha, A beta, and A gamma) were immunologically different; although SDS-urea gel electrophoresis showed that A gamma HC was apparently resistant to the digestion, actually three distinct HCs contributed to the same band alternately. H fragment was derived from A beta and A gamma HCs, whereas L fragment originated from A alpha HC. Since both fragments were associated with ATPase activity, these results directly demonstrate the presence of multiple ATPase sites in Tetrahymena 22S dynein.
Control of a car-like robot using a dynamic model

A solution to the problem of controlling a car-like nonholonomic robot is proposed using a "virtual" vehicle approach, which is shown to be robust with respect to errors and disturbances. The proposed algorithms are model independent, and the stability analysis is done using a dynamical model in which, for instance, the side slip angles are taken into account.
The Effect of Thyroid Hormone, Prostaglandin E2, and Calcium Gluconate on Orthodontic Tooth Movement and Root Resorption in Rats

Statement of the Problem A major objective of investigators is to clarify the role of metabolites in achievement of maximum tooth movement with minimal root damage during orthodontic tooth movement (OTM). Purpose The aim of this study was to determine the effect of administration of thyroid hormone, prostaglandin E2, and calcium on orthodontic tooth movement and root resorption in rats. Materials and Method Sixty four male Wistar rats were randomly divided into 8 groups of eight rats each: 1- 20µg/kg thyroxine was injected in traperitoneally after installation of the orthodontic appliance. 2- 0.1 ml of 1 mg/ml prostaglandin E2 was injected submucosally. 3- 10% (200 mg/kg) calcium gluconate was injected. 4- Prostaglandin E2 was injected submucosally and 10% calcium was injected intraperitoneally. 5- Thyroxine was injected intraperitoneally and prostaglandin E2 was injected submucosally. 6- 20µg/kg thyroxine with calcium was injected. 7- Prostaglandin E2 was injected submucosally with calcium and thyroxine. 8- Distilled water was used in control group. The orthodontic appliances comprised of a NiTi closed coil were posteriorly connected to the right first molar and anteriorly to the upper right incisor. OTM was measured with a feeler gauge. The mid-mesial root of the first molar and the adjacent tissues were histologically evaluated. The Data were analyzed by one-way ANOVA and Student-Newman-Keuls test. Results The highest mean OTM was observed in the thyroxine and prostaglandin E2 group (Mean±SD = 0.7375±0.1359 mm) that was significantly different (p< 0.05). A significant difference (p< 0.05) in root resorption was observed between the prostaglandin E2 (0.0192±0.0198 mm2) and the other groups. Conclusion It seems that the combination of thyroxine and prostaglandin E2, with a synergistic effect, would decrease the root resorption and increase the rate of orthodontic tooth movement in rats.
Orbifolds and flows from gauged supergravity

We examine orbifolds of the IIB string via gauged supergravity. For the gravity duals of the A_{n-1} quiver gauge theories, we extract the massless degrees of freedom and assemble them into multiplets of N=4 gauged supergravity in five dimensions. We examine the embedding of the gauge group into the isometry group of the scalar manifold, as well as the symmetries of the scalar potential. From this we find that there is a large SU(1,n) symmetry group which relates different RG flows in the dual quiver gauge theory. We find that this symmetry implies an extension of the usual duality between ten-dimensional IIB solutions which involves exchanging geometric moduli with background fluxes.
Pseudometathesis in three Standard Arabic broken-plural templates1

This paper suggests that what McCarthy and Prince (1990), following Levy (1971), call consonant-vowel metathesis in three Standard Arabic broken-plural templates is more likely a two-step diachronic process of pseudometathesis in the sense of Blevins and Garrett (1998). This process is characterized by vowel deletion followed by vowel insertion. Evidence from present-day dialects, mainly Lebanese Arabic and Moroccan Arabic, is used to argue that this alternative analysis is the more plausible analysis.
Throughput performance improvement in cognitive radio networks based on spectrum prediction

Spectrum sensing is used to detect spectrum holes and find active primary users while randomly selecting channel for sensing leads to secondary user's low throughput in cognitive radio networks. Spectrum prediction forecasts future channel status on the basis of historical information, and BP neural network is used as an example of the prediction method. Second users' frame structure is redesigned in this paper based on spectrum prediction, aiming to select the most likely idle channel for sensing. Theoretical and simulation results show that secondary users' throughputs are significantly improved by spectrum prediction. Correlations both in the frequency domain and time domain are compared, and the impacts of the prediction method, traffic intensity, and channel number on the throughput are also investigated in this study.
Comparative Sequence Analysis of Human and Mouse Promoter Regions

The DNA sequence just adjacent to the transcriptional start sites (TSSs), what we call the promoter, plays an important role in transcription regulation. Although many attempts have been made to detect functional signals in promoter regions aiming to understand the mechanisms of transcription regulation, those attempts remain challenges because the grammars or semantics of promoter sequences are not fully unveiled. The completion of genome sequences has made the large scale genomic comparison an effective tool for mining the signals from genome sequences. In addition, experimentally validated TSS data has been accumulating in these years [1], which made possible the comparisons of the promoter sequences [2]. The TSS data are especially abundant for human and mouse. In this study, we carried out the most comprehensive comparison to date for promoter regions of human and mouse, and the relationship between gene function and promoter conservation were examined.
Research on the Trust in Supply Chain Dynamic Collaboration Based on MAS

On the basis of dynamic trust theory, the paper proposes a staggered theoretic model which describes dynamic collaboration trust in supply chain from the view of collaboration relationship, which studies the dynamic dissimilar effect of institution-based trust on collaboration trust and cooperation intention in differential stage. More than forty supply chain companies in different fields are chosen to be the objects of experimental research and a sample data of more than three hundred actual members is finally collected. Fact or analysis and structural equation modeling are implemented to validate the hypothesized relationship between institution-based trust, collaboration trust in supply chain trust, and cooperation intention in theoretic model.
Effects of Representation on Solving Complex Spatial-Temporal Problems

We present a study of how humans represent space when solving Tower Defense puzzles, a complex spatial reasoning task requiring the subject to protect locations by arranging a set of defense towers at strategic positions. We have discovered that the representation humans use is significantly more complex than what is needed to describe the spatial situation. Strategy and spatial representations are tightly intertwined with spatial representations forgoing objective, atomically-defined spatial features for context-sensitive, goal-oriented spatial affordances. Spatial relationships exist not only between objects but between an object’s properties, second-order properties, joint spatial properties and temporal properties.
Third-person Diagnostic Interview on the Cognitive Insight Level of Psychotic Patients with an Insight at the Denial Level

Objectives: According to the previous findings, the third-person technique improved the clinical insight of psychotic patients, therefore the present study aims to examine the effect of a third-person interview compared to a first-person interview on the level of cognitive insight of psychotic patients with an insight at the denial level. Materials and Methods: In this study, using interviews and questionnaires, a total number of 44 patients of Razi Psychiatric Educational and Treatment Center with an insight at the denial level being assessed using diagnostic interviews were divided randomly into two groups. Then, the two groups of patients' cognitive insights were evaluated using Beck Cognitive Insight Scale. Results: The findings indicated that in psychotic patients with an insight at the denial level, the third-person technique of interview compared to the first-person had little effect on the improvement of overall cognitive insight and its components, including self-reflection and self-assurance; however, this effect was not strong enough to make a significant difference between the two groups of patients. Conclusion: According to the study findings, we can conclude that the third-person interview compared to the first-person interview has no effect on the improvement of the cognitive insight of psychotic patients with an insight at the denial level. This finding is consistent with the previous studies indicating that although the theory of mind has some correlations with the clinical insight of patients, it has no effect on their cognitive insight.
Chapter 1 TOWARD THE PLACEMENT OF POWER MANAGEMENT POINTS IN REAL-TIME APPLICATIONS ∗

Dynamically changing CPU voltage and frequency have been shown to greatly save the processor energy. These adjustments can be done at specific power management points (PMPs), which are not without overheads. In this work we study the effect of different overheads on both time and energy; these can be seen as the overhead of computing the new speed, and then the overhead of dynamically adjusting the speed. We propose a theoretical solution for choosing the granularity of inserting PMPs in a program taking into consideration such overheads. We validate our theoretical results and show that the accuracy of the theoretical model is between zero and five management points of simulation results.
A case of malignant otitis externa caused by Candida glabrata in a patient receiving haemodialysis

A 74-y-old male receiving haemodialysis presented with right-sided otalgia, otorrhoea and diffuse swelling on the right external auditory canal. Following an initial successful treatment with prolonged intravenous antibiotics, the patient relapsed with a secondary infection in the same site due to Candida glabrata. We report an unusual case of malignant otitis externa caused by the fungus C. glabrata.
A Single-Blinded, Randomized Comparison of Laparoscopic Versus Open Hernia Repair in Children

OBJECTIVE. The role of laparoscopic surgery in pediatric inguinal hernia repair is unclear. We aimed to compare day-case laparoscopic hernia repair with open repair. METHODS. A prospective, single-blinded randomized study in children aged 4 months to 16 years with unilateral inguinal hernia was performed. The primary outcome measure was the time to normal daily activities after surgery. Secondary outcome measures included postoperative pain, time in the operation room, results, and complications. RESULTS. Eighty-nine patients were enrolled (laparoscopic hernia repair: 47, open repair: 42). The mean number of days to normal activity after laparoscopic hernia repair and open repair was 2.4 and 2.5, respectively. Thirty-seven (79%) patients with laparoscopic hernia repair and 20 (42%) with open repair required rescue analgesia postoperatively. The median pain score in the second postoperative morning was significantly higher after laparoscopic hernia repair. The median times in the operation room for laparoscopic hernia repair and open repair were 63 and 38 minutes, respectively. Surgical and cosmetic results were similar at up to 2 years' follow-up. CONCLUSIONS. Recovery and outcome were similar after open repair and laparoscopic hernia repair in children. Laparoscopic hernia repair was associated with increased theater time and postoperative pain.
Minimizing N -detect Tests for Combinational Circuits Minimizing N -detect Tests for Combinational Circuits Minimizing N -detect Tests for Combinational Circuits

Except where reference is made to the work of others, the work described in this thesis is my own or was done in collaboration with my advisory committee. This thesis does not include proprietary or classified information. Permission is granted to Auburn University to make copies of this thesis at its discretion, upon the request of individuals or institutions and at their expense. An N-detect test set detects each stuck-at fault by at least N different vectors. N-detect tests are of practical interest because of their ability to improve the defect coverage. The main problem that limits their use is their size. Researchers have proposed various methods to generate N-detect tests, but not much work has been done on minimizing them. Also, there is no clear minimum size estimate of an N-detect test set. We provide a theoretical lower bound on the size of an N-detect test set. This is derived using the independent fault set concept proposed by Akers et al. An independent fault set (IFS) is a set of faults in which no two faults are detectable by the same vector. A known lower bound on the size of any single-detect test set is equal to the size of the largest IFS. We show that the lower bound on the size of an N-detect test set is N times the size of the largest IFS. Given any N-detect vector set, we derive a minimal N-detect vector set from it. Integer linear programming (ILP) is used to find the smallest set. Each vector is assigned an integer [0,1] variable such that 1 means that the vector is included in, and 0 means that it is excluded v from, the minimized set. Faults are simulated without fault dropping and that result is used to formulate the ILP model. The model consists of a single N-detection constraint for each fault and an objective function to be minimized, which is the sum of all integer variables. The problem is then solvable by any ILP solver program. The ILP method, when applied to the ISCAS85 benchmark circuits, produces better results compared to an earlier N-detect test minimization method [64]. For most circuits, an order of magnitude reduction in the minimized test set size is achieved. For the circuit c1355, the earlier minimization method produced a 15-detect test set of size 1274 in 5674.6 seconds, while our ILP method produced a test set of …
Research on Similar Materials for Rheological Test of Hard Rock Mass

The analog material, used in the Geo-mechanical model test that is designed to study the unloading rheological behavior and failure characteristics of rock mass, must reflect the physico-mechanical behaviors of the actual rock mass. The surrounding rock of Meng-di-gou hydropower station is in complex geological conditions. With the excavation of the rock mass, the surrounding rock gradually unloading, and the property of the near rock mass. It is necessary to carry out Geo-mechanical model test to study the rheological properties of deep rock mass under complicated geological conditions. So the similar material, comprised of iron powder, barite powder, and quartz sands bound with a solution of alcohol and colophonium, is suggested to be improvable. Firstly, through more than 300 groups of mix proportion tests, the influence of different mix proportions of the ingredients are analyzed to obtain the optimal analog materials; Secondly, more than 1200 specimens are made into size Φ50mm×100mm; Lastly, physico-mechanical tests were conducted by using the specimens to test the mechanical property of the similar material, and the basic physico-mechanical parameters are obtained from the analog material. The results indicates that the property of the similar material matches well with that of the rock mass in site, so the similar material is suitable for the Geo-mechanical model test, and it can be used to test the unloading rheological behavior of rock mass of Meng-di-gou hydropower station.
Polymorphisms in the Inflammatory Pathway Genes TLR2, TLR4, TLR9, LY96, NFKBIA, NFKB1, TNFA, TNFRSF1A, IL6R, IL10, IL23R, PTPN22, and PPARG Are Associated with Susceptibility of Inflammatory Bowel Disease in a Danish Cohort

Background The inflammatory bowel diseases (IBD), Crohn's disease (CD) and ulcerative colitis (UC), result from the combined effects of susceptibility genes and environmental factors. Polymorphisms in genes regulating inflammation may explain part of the genetic heritage. Methods Using a candidate gene approach, 39 mainly functional single nucleotide polymorphisms (SNPs) in 26 genes regulating inflammation were assessed in a clinical homogeneous group of severely diseased patients consisting of 624 patients with CD, 411 patients with UC and 795 controls. The results were analysed using logistic regression. Results Sixteen polymorphisms in 13 genes involved in regulation of inflammation were associated with risk of CD and/or UC (p≤0.05). The polymorphisms TLR2 (rs1816702), NFKB1 (rs28362491), TNFRSF1A (rs4149570), IL6R (rs4537545), IL23R (rs11209026) and PTPN22 (rs2476601) were associated with risk of CD and the polymorphisms TLR2 (rs1816702), TLR4 (rs1554973 and rs12377632), TLR9 (rs352139), LY96 (rs11465996), NFKBIA (rs696), TNFA (rs1800629), TNFRSF1A (rs4149570), IL10 (rs3024505), IL23R (rs11209026), PTPN22 (rs2476601) and PPARG (rs1801282) were associated with risk of UC. When including all patients (IBD) the polymorphisms TLR2 (rs4696480 and rs1816702), TLR4 (rs1554973 and rs12377632), TLR9 (rs187084), TNFRSF1A (rs4149570), IL6R (rs4537545), IL10 (rs3024505), IL23R (rs11209026) and PTPN22 (rs2476601) were associated with risk. After Bonferroni correction for multiple testing, both the homozygous and the heterozygous variant genotypes of IL23R G>A(rs11209026) (ORCD,adj: 0.38, 95% CI: 0.21–0.67, p = 0.03; ORIBD,adj 0.43, 95% CI: 0.28–0.67, p = 0.007) and PTPN22 1858 G>A(rs2476601) (ORCD,unadj 0.54, 95% CI: 0.41–0.72, p = 7*10−4; ORIBD,unadj: 0.61, 95% CI: 0.48–0.77, p = 0.001) were associated with reduced risk of CD. Conclusion The biological effects of the studied polymorphisms suggest that genetically determined high inflammatory response was associated with increased risk of CD. The many SNPs found in TLRs suggest that the host microbial composition or environmental factors in the gut are involved in risk of IBD in genetically susceptible individuals.