Miracle-dz/UniFAR-FTUs huggingface dataset:
THE STAR FORMATION IN RADIO SURVEY: GBT 33 GHz OBSERVATIONS OF NEARBY GALAXY NUCLEI AND EXTRANUCLEAR STAR-FORMING REGIONS

We present 33 GHz photometry of 103 galaxy nuclei and extranuclear star-forming complexes taken with the Green Bank Telescope as part of the Star Formation in Radio Survey. Among the sources without evidence for an active galactic nucleus, and also having lower frequency radio data, we find a median thermal fraction at 33 GHz of ≈76% with a dispersion of ≈24%. For all sources resolved on scales ≲0.5 kpc, the thermal fraction is even larger, being ≳90%. This suggests that the rest-frame 33 GHz emission provides a sensitive measure of the ionizing photon rate from young star-forming regions, thus making it a robust star formation rate (SFR) indicator. Taking the 33 GHz SFRs as a reference, we investigate other empirical calibrations relying on different combinations of warm 24 μm dust, total infrared (IR; 8–1000 μm), Hα line, and far-UV continuum emission. The recipes derived here generally agree with others found in the literature, albeit with a large dispersion that most likely stems from a combination of effects. Comparing the 33 GHz to total IR flux ratios as a function of the radio spectral index, measured between 1.7 and 33 GHz, we find that the ratio increases as the radio spectral index flattens which does not appear to be a distance effect. Consequently, the ratio of non-thermal to total IR emission appears relatively constant, suggesting only moderate variations in the cosmic-ray electron injection spectrum and ratio of synchrotron to total cooling processes among star-forming complexes. Assuming that this trend solely arises from an increase in the thermal fraction sets a maximum on the scatter of the non-thermal spectral indices among the star-forming regions of .
Intimin from enteropathogenic Escherichia coli mediates remodelling of the eukaryotic cell surface.

Adhesion to cultured epithelial cells by enteropathogenic Escherichia coli (EPEC) is associated with extensive rearrangement of the host cell cytoskeleton. Evidence has been presented that EPEC adhesion is associated with activation of signal transduction pathways leading to production of a characteristic histopathological feature known as the attaching and effacing (A/E) lesion. A/E lesion formation requires intimin, an EPEC adhesion molecule and several EPEC secreted proteins (EspA, B, D and Tir) involved in cell signalling and protein translocation. In this study it is shown that HEp-2 cells respond during the early stages of infection with two wild-type EPEC strains (B171 and E2348/69) by producing microvillus-like processes (MLP) at the site of initial bacterial adherence. Intimin appears to play a key role in MLP elongation. At later stages of infection with these wild-type EPEC strains, when A/E lesions have formed, the MLP were reduced in number and length to appear as at time zero, and the cell surface in the vicinity of bacterial clusters appeared unaffected. In contrast, infection with EspA- or EspB-negative, but intimin-positive, EPEC strains (UMD872 and UMD864, respectively) resulted in enhanced MLP proliferation and formation of 'cage-like' structures engulfing the bacteria. Inoculating HEp-2 cells with intimin-coated latex spheres induced similar 'cage-like' structures. Caco-2 cells did not show intimin-induced microvillus elongation in response to EPEC infection, although microvillus effacement and reduction in number occurred. Similar phenomena appeared on B171 and E2348/69 infection of paediatric intestine using in vitro organ culture, i.e. elongated microvilli were seen in association with small colonies and at the periphery of large localized colonies, along with evidence of microvillus breakdown and debris in the colony centre. These results show that intimin activates signal transduction pathways involved in the remodelling of the eukaryotic cell surface, probably via binding to a receptor encoded by the host cell.
TRIP6 Enhances Lysophosphatidic Acid-induced Cell Migration by Interacting with the Lysophosphatidic Acid 2 Receptor*

Lysophosphatidic acid (LPA) induces actin rearrangement, focal adhesion assembly, and cell migration through the activation of small G protein Rho and its downstream effectors. These diverse cellular responses are mediated by its associated G protein-coupled receptors. However, the mechanisms and specificity by which these LPA receptors mediate LPA actions are still poorly understood. Here we show that LPA stimulation promotes the interaction of the LPA2 receptor with a focal adhesion molecule, TRIP6 (thyroid receptor interacting protein 6)/ZRP-1 (zyxin-related protein 1). TRIP6 directly binds to the carboxyl-terminal tail of the LPA2 receptor through its LIM domains. LPA-dependent recruitment of TRIP6 to the plasma membrane promotes its targeting to focal adhesions and co-localization with actin stress fibers. In addition, TRIP6 associates with the components of focal complexes including paxillin, focal adhesion kinase, c-Src, and p130cas in an agonist-dependent manner. Overexpression of TRIP6 augments LPA-induced cell migration; in contrast, suppression of endogenous TRIP6 expression by a TRIP6-specific small interfering RNA reduces it in SKOV3 ovarian cancer cells. Strikingly, the association with TRIP6 is specific to the LPA2 receptor but not LPA1 or LPA3 receptor, indicating a specific role for TRIP6 in regulating LPA2 receptor-mediated signaling. Taken together, our results suggest that TRIP6 functions at a point of convergence between the activated LPA2 receptor and downstream signals involved in cell adhesion and migration.
UWB wireless positioning technology in the application

Ultra-Wideband (UWB) technology with high data transfer rate, high temporal resolution and the advantages of strong penetrability, in short distance, the complex environment in the wireless sensor network location technology has attracted great interest. This article mainly through to the development of UWB technology and combining with a large number of the latest work, summarizes the technical development trajectory, discusses the location in the wireless network based on the technology of UWB technology, the algorithm. Combined with some of the latest research results, based on UWB wireless positioning technology is still existing problems and development direction.
Solving Uncertain MDPs with Objectives that Are Separable over Instantiations of Model Uncertainty

Markov Decision Problems, MDPs offer an effective mechanism for planning under uncertainty. However, due to unavoidable uncertainty over models, it is difficult to obtain an exact specification of an MDP. We are interested in solving MDPs, where transition and reward functions are not exactly specified. Existing research has primarily focussed on computing infinite horizon stationary policies when optimizing robustness, regret and percentile based objectives. We focus specifically on finite horizon problems with a special emphasis on objectives that are separable over individual instantiations of model uncertainty (i.e., objectives that can be expressed as a sum over instantiations of model uncertainty): (a) First, we identify two separable objectives for uncertain MDPs: Average Value Maximization (AVM) and Confidence Probability Maximisation (CPM). (b) Second, we provide optimization based solutions to compute policies for uncertain MDPs with such objectives. In particular, we exploit the separability of AVM and CPM objectives by employing Lagrangian dual decomposition(LDD). (c) Finally, we demonstrate the utility of the LDD approach on a benchmark problem from the literature.
Refactored Design of I/O Architecture for Flash Storage

Flash storage devices behave quite differently from hard disk drives (HDDs); a page on flash has to be erased before it can be rewritten, and the erasure has to be performed on a block which consists of a large number of contiguous pages. It is also important to distribute writes evenly among flash blocks to avoid premature wearing. To achieve interoperability with existing block I/O subsystems for HDDs, NAND flash devices employ an intermediate software layer, called the flash translation layer (FTL), which hides these differences. Unfortunately, FTL implementations require powerful processors with a large amount of DRAM in flash controllers and also incur many unnecessary I/O operations which degrade flash storage performance and lifetime. In this paper, we present a refactored design of I/O architecture for flash storage which dramatically increases storage performance and lifetime while decreasing the cost of the flash controller. In comparison with page-level FTL, our preliminary experiments show a reduction of 19 percent in I/O operations, improvement of I/O performance by 9 percent and storage lifetime by 36 percent. In addition, our scheme uses only 1 128 DRAM memory in the flash controller.
A Complete Multi-Processor System-on-Chip FPGA-Based Emulation Framework

With the growing complexity in consumer embedded products and the improvements in process technology, multiprocessor system-on-chip (MPSoC) architectures have become widespread. These new systems are very complex to design as they must execute multiple complex real-time applications (e.g. video processing, or videogames), while meeting several additional design constraints (e.g. energy consumption or time-to-market). Therefore, mechanisms to efficiently explore the different possible HW-SW design interactions in complete MPSoC systems are in great need. In this paper, we present a new FPGA-based emulation framework that allows designers to rapidly explore a large range of MPSoC design alternatives at the cycle-accurate level. Our results show that the proposed framework is able to extract a number of critical statistics from processing cores, memory and interconnection systems, with a speed-up of three orders of magnitude compared to cycle-accurate MPSoC simulators
Sixty-Year Changes in Residential Landscapes in Beijing: A Perspective from Both the Horizontal (2D) and Vertical (3D) Dimensions

Landscape changes associated with urbanization can lead to many serious ecological and environmental problems. Quantifying the vertical structure of the urban landscape and its change is important to understand its social and ecological impacts, but previous studies mainly focus on urban horizontal expansion and its impacts on land cover/land use change. This papers focuses on the residential landscape to investigate how the vertical dimension of the urban landscape (i.e., building height) change through time, and how such change is related to changes in the horizontal dimension of the landscape, using Beijing, the capital of China, as a case study. We quantified the expansion of the residential neighborhoods from 1949 to 2009, and changes in vegetation coverage, building density, and building height within these neighborhoods, using 1 m spatial resolution imagery. One-way ANOVA and correlation analysis were used to examine the relationships of building height to vegetation coverage and building density. We found: (1) The residential areas expanded rapidly and were dominated by outward growth, with much less within-city infilling. The growth rate varied greatly through time, first increasing from 1949–2004 and then decreasing from 2005–2009. The expansion direction of newly built residential neighborhoods shifted from west to north in a clockwise direction. (2) The vertical structure of residential neighborhoods changed with time and varied in space, forming a “low-high” pattern from urban central areas to the urban edges within the 5th ring road of Beijing. (3) The residential neighborhoods built in different time periods had significant differences in vegetation coverage, building density, and building height. The residential neighborhoods built in more recent years tended to have taller buildings, lower building density and lower vegetation coverage.
Calendario Seminari e Convegni di Dipartimento

This paper investigates whether Twitter can be conceived of as a public sphere or an echo chamber. By using big data, data mining and network analysis, we predicted the political orientation of the users and measured the political homophily in the graph. Evidence was found that supports the echo chamber view. Furthermore, we found that Democrats’ political homophily is associated with political ideology, while Republicans’ political homophily with political affiliation
The private is political: Women and family in intellectual Islam

In Hiba Ra’uf’s Woman and Political Work, she argues that the family is the basic political unit of the Islamic community or nation (the umma). Her thesis is both feminist and Islamist, as she argues that the ‘private is political’. By drawing analogies between family and umma, family and caliphate, the personal and the political, the private and public, Ra’uf seeks to dismantle the oppositions of secular society, to challenge the division of society into discrete spheres. This entails an implicit challenge to the secular state, but effected through the politics of the family. An Islamic family, she argues, is a powerful site for the transformation of socio-political institutions; a politics of the microcosmic with macrocosmic ramifications, effected through the very embodiment and practice of an Islamic ethos at a grassroots, capillary level. However, though Ra’uf contests liberal secularism’s division of spheres with feminist and Islamist critical methods, she reproduces some of its fundamental assumptions about the nature of the family: as the domain of religion, in opposition to the secular state; as rooting community, in opposition to the individualism of the citizen; as an ethics grounded in affect; and as an essentially feminine world. In making the family the sphere of Islamic politics, Ra’uf re-enacts secularism’s division of spheres, sacralizing the affective bonds of intimate relations and making the family the domain of religion. Furthermore, by emphasizing the family as the domain of women’s political work, she reinscribes the family as a feminine sphere, so that woman’s vocation is familial, as is her ethical disposition.
Improving Performance Using Torque Vectoring on an Electric All-Wheel-Drive Formula

Various forms of electronic stability, traction and launch control have existed for over two decades, improving safety, sports performance and off-road capabilities of vehicles. These technologies involve individual control of each wheel’s drive torque or braking force in response to the dynamics of the driving conditions and the driver’s intentions. With the exception of launch control, applications of these electronic handling-improvement systems are rarely seen on the Formula SAE platform. This is mostly due to the limitations of a combustion engine and conventional drivetrain; individual control of torque to each wheel requires additional mechanical systems adding unjustifiable weight and complexity for the resulting gains. However, an all-wheel-drive electric Formula SAE vehicle with four individual hub motors has the potential for experiments with torque vectoring via electronic means, with minimal additional mechanical systems. The University of Western Australia’s Renewable Energy Vehicle (REV) group has been designing such a vehicle for the 2013 Formula SAE competition in Melbourne. Processing driver inputs such as steering angle, throttle and brake position in addition to the actual dynamic state of the vehicle observed through wheel speeds, three axes of acceleration and angular velocities, a torque vectoring algorithm has been designed and implemented on an ARM Cortex M3 microcontroller and has achieved significant improvements in cornering performance.
Enhancing Relationships Between Children and Teachers

Why Supportive Relationships Are Essential How the Parts Affect the Whole - Systems Theory in Classroom Relationships The Child as a Developing System The Emotional Bond Between Children and Adults Examples from Life Counselling Teachers - the Key to Affecting Child-Teacher Relationships Enhancing the Relationships of the Classroom How School Policy Affects the Child Teacher Relationship Strong Relationships Mean Less Risk - an Agenda for Practice and Research.
Accuracy and Time Delay of Glucose Measurements of Continuous Glucose Monitoring and Bedside Artificial Pancreas During Hyperglycemic and Euglycemic Hyperinsulinemic Glucose Clamp Study

Background: Glucose values of continuous glucose monitoring (CGM) have time delays compared with plasma glucose (PG) values. The artificial pancreas (STG-55, Nikkiso, Japan) (AP), which measures venous blood glucose directly, also has a time delay because of the long tubing lines from sampling vessel to the glucose sensor. We investigate accuracy and time delay of CGM and AP in comparison with PG values during 2-step glucose clamp study. Methods: Seven patients with type 2 diabetes and 2 healthy volunteers were included in this study. CGM (Enlite sensor, Medtronic, Northridge, CA, USA) was attached on the day before the experiment. Hyperglycemic (200 mg/dL) clamp was performed for 90 minutes, followed by euglycemic (100 mg/dL) hyperinsulinemic (100 μU/mL) clamp for 90-120 minutes using AP. CGM sensor glucose was calibrated just before and after the clamp study. AP and CGM values were compared with PG values. Results: AP values were significantly lower than PG values at 5, 30 minute during hyperglycemic clamp. In comparison, CGM value at 0 minute was significantly higher, and its following values were almost significantly lower than PG values. The time delay of AP and CGM values to reach maximum glucose levels were 5.0 ± 22.3 (NS) and 28.6 ± 32.5 (P < .05) min, respectively. Mean absolute rate difference of CGM was significantly higher than AP (24.0 ± 7.6 vs 15.3 ± 4.6, P < .05) during glucose rising period (0-45 min); however, there were no significant differences during other periods. Conclusions: Both CGM and AP failed to follow plasma glucose values during nonphysiologically rapid glucose rising, but indicated accurate values during physiological glucose change.
Beta‐carotene, carotenoids, and disease prevention in humans

A growing body of literature exists regarding the effects of beta‐carotene and other carotenoids on chronic diseases in humans. This article reviews and critically evaluates this literature and identifies areas for further research. This review is restricted to studies in humans, with a major emphasis on the most recent literature in the area of carotenoids and selected cancers. Effects of carotenoids on cardiovascular diseases, photosensitivity diseases, cataracts, and age‐related macular degeneration are also discussed briefly. Numerous observational studies have found that people who ingest more carotenoids in their diets have a reduced risk of several chronic diseases. However, intervention trials of supplemental beta‐carotene indicate that supplements are of little or no value in preventing cardiovascular disease and the major cancers occurring in well‐nourished populations, and may actually increase, rather than reduce, lung cancer incidence in smokers. As a consequence of these findings, some of the ongoing trials of beta‐carotene and disease prevention have been terminated or have dropped beta‐carotene from their interventions. Researchers should now seek explanations for the apparently discordant findings of observational studies vs. intervention trials. The most pressing research issues include studies of interactions of carotenoids with themselves and with other phytochemicals and mechanistic studies of the actions of beta‐carotene in lung carcinogenesis and cardiovascular disease. Paradoxically, the finding that lung carcinogenesis and cardiovascular disease can be enhanced by sup‐plemental beta‐carotene may ultimately lead to a clearer understanding of the role of diet in the etiology and prevention of these diseases. The con‐clusion that major public health benefits could be achieved by increasing consumption of carotenoid‐ rich fruits and vegetables still appears to stand; however, the pharmacological use of supplemental beta‐carotene for the prevention of cardiovascular disease and lung cancer, particularly in smokers, can no longer be recommended. —Mayne, S. T. Betacarotene, carotenoids, and disease prevention in humane. FASEB J. 10, 690‐701 (1996)
HoppingDuster: self-adaptive cleaning robot based on aerial vehicle

Home cleaning robots have become popular. Most of the home cleaning robots are based on ground vehicles. While the cleaning robots based on ground vehicles can vacuum or wash floors robustly and efficiently, but they only clean on floors, not on stairs or furnitures. In this demo, we show a new concept of cleaning robot, called HoppingDuster. HoppingDuster is based on an aerial vehicle, which can y to stairs or furnitures to be cleaned, and hop or hover to wipe or blow down dust on them toward the floor so that the ground cleaning robot can vacuum the dust. HoppingDuster adapts its behavior to finish it cleaning within designated time and battery capacity.
Biweekly chemotherapy with oxaliplatin, irinotecan, infusional Fluorouracil, and leucovorin: a pilot study in patients with metastatic colorectal cancer.

PURPOSE To determine the feasibility, recommended doses, plasma pharmacokinetics, and antitumor activity of a biweekly chemotherapy regimen with oxaliplatin (L-OHP), irinotecan (CPT-11), infusional fluorouracil (5-FU), and leucovorin (LV) in metastatic colorectal cancer patients. PATIENTS AND METHODS Patients received CPT-11 followed by L-OHP and LV 200 mg/m(2) and followed by 5-FU 3,800 mg/m(2) as a 48-hour infusion, repeated every 2 weeks. In the first part of the study, an escalation of CPT-11 dose and/or a decrease of the L-OHP dose were planned. Once the recommended doses of CPT-11 and L-OHP were determined, all subsequent patients were treated at the recommended doses. RESULTS Forty-two patients entered the study. CPT-11 175 mg/m(2) and L-OHP 100 mg/m(2) in combination with LV 200 mg/m(2) and 5-FU 3,800 mg/m(2) could be administered with acceptable toxicities; 39 patients were treated at these dose levels. The pharmacokinetics parameters of the agents used and their metabolites did not seem to be influenced by the concomitant use of the other drugs. The most relevant toxicities were diarrhea and neutropenia, with 14% of patients experiencing one episode of febrile neutropenia. In five patients (11.9%) a complete and in 25 (59.5%) a partial response was demonstrated, for an objective response rate of 71.4% (95% confidence interval, 47% to 83%). In 11 patients (26%), a surgical resection of residual disease could be performed. Median progression-free and overall survival times were 10.4 and 26.5 months, respectively. CONCLUSION This biweekly regimen is feasible and has acceptable and manageable toxicities and no apparent relevant pharmacokinetics interactions. This combination is associated with a promising antitumor activity, time to progression, and survival. A phase III randomized trial in Italy planned by the Gruppo Oncologico Nord Ovest has just started.