Miracle-dz/UniFAR-FTUs huggingface dataset:
Towards the identification of situational barriers to creative behaviors: The development of a self‐report inventory

Abstract: Four clusters of obstacles have been obtained from the Jones Inventory of Barriers (JIB), a self‐report inventory designed to investigate barriers to individual creativity in organizational environments. The barriers have been modelled as strategic, values, perceptual, and self‐image factors. Statistical evidence is presented for the reliability and validity of the measure across convenience samples of English speaking respondents (N=364). Correlational patterns between the barriers and a battery of established tests of creativity are complex, but satisfactory, as the barriers were negatively correlated with the creativity measures. Significant differences in mean scores for some barriers were found across the sampled occupational groups, including graduate engineers, architects, and business graduates. The JIB offers promise in a range of diagnostic and personal development situations.
Exploiting parallel texts in the creation of multilingual semantically annotated resources: the MultiSemCor Corpus

In this article we illustrate and evaluate an approach to create high quality linguistically annotated resources based on the exploitation of aligned parallel corpora. This approach is based on the assumption that if a text in one language has been annotated and its translation has not, annotations can be transferred from the source text to the target using word alignment as a bridge. The transfer approach has been tested and extensively applied for the creation of the MultiSemCor corpus, an English/Italian parallel corpus created on the basis of the English SemCor corpus. In MultiSemCor the texts are aligned at the word level and word sense annotated with a shared inventory of senses. A number of experiments have been carried out to evaluate the different steps involved in the methodology and the results suggest that the transfer approach is one promising solution to the resource bottleneck. First, it leads to the creation of a parallel corpus, which represents a crucial resource per se. Second, it allows for the exploitation of existing (mostly English) annotated resources to bootstrap the creation of annotated corpora in new (resource-poor) languages with greatly reduced human effort.
Isolation of cDNA clones using yeast artificial chromosome probes

The cloning of large DNA fragments of hundreds of kilobases in Yeast artificial chromosomes, has simplified the analysis of regions of the genome previously cloned by cosmid walking. The mapping of expressed sequences within cosmid contigs has relied on the association of genes with sequence motifs defined by rare-cutting endonucleases, and the identification of sequence conservation between species. We reasoned that if the contribution of repetitive sequences to filter hybridizations could be minimised, then the use of large cloned DNAs as hybridisation probes to screen cDNA libraries would greatly simplify the characterisation of hitherto unidentified genes. In this paper we demonstrate the use of this approach by using a YAC, containing 180 kb of human genomic DNA including the aldose reductase gene, as a probe to isolate an aldose reductase cDNA from a lambda gt11 human foetal liver cDNA library.
School leadership and information communication technology

Leadership is an important component in guiding the teaching-learning process. Principal as school leaders have a major responsibility for initiating and implementing school change through the use of Information and Communication Technology (ICT) and can facilitate complex decision to integrate it into learning, teaching and school administration. Hence, educational leaders must understand, promote and implement the notion that technology integration is not about the technology; it is about focusing on the future generations and leading teachers to a change in pedagogy. However, few studies have empirically examined computer use by principals, their perceived computer competence and their leadership style. This paper will report on these issues from an initial analysis of a baseline data gathered from 30 secondary school principals in Tehran, a large province in Iran. Findings indicate that school principals are using computers for instructional and administrative purposes and they have moderate competency in computer applications. This paper also suggests that the idea of transformational leaders can enhance the computer use in schools. Hence, policy makers must design professional development programs, such as leadership studies, in order to teach the components of transformational leadership; idealized influence, inspirational motivation, intellectual stimulation and individual consideration to future administrators.
Transfer of glutamine between astrocytes and neurons

The export of glutamine from astrocytes, and the uptake of glutamine by neurons, are integral steps in the glutamate‐glutamine cycle, a major pathway for the replenishment of neuronal glutamate. We review here the functional and molecular identification of the transporters that mediate this transfer. The emerging picture of glutamine transfer in adult brain is of a dominant pathway mediated by system N transport (SN1) in astrocytes and system A transport (SAT/ATA) in neurons. The participating glutamine transporters are functionally and structurally related, sharing the following properties: (a) unlike many neutral amino acid transporters which have proven to be obligate exchangers, these glutamine transporters mediate net substrate transfer energized by coupling to ionic gradients; (b) they are sensitive to small pH changes in the physiological range; (c) they are susceptible to adaptive and humoral regulation; (d) they are related structurally to the AAAP (amino acid and auxin permeases) family of transporters. A key difference between SN1 and the SAT/ATA transporters is the ready reversibility of glutamine fluxes via SN1 under physiological conditions, which allows SN1 both to sustain a glutamine concentration gradient in astrocytes and to mediate the net outward flux of glutamine. It is likely that the ASCT2 transporter, an obligate exchanger of neutral amino acids, displaces the SN1 transporter as the main carrier of glutamine export in proliferating astrocytes.
Magnesium Modulates Actin Binding and ADP Release in Myosin Motors*

Background: Magnesium may be an important physiological regulator of myosin motor activity. Results: Mg2+ inhibits the ADP release rate constant in the subset of myosins examined and reduces actin affinity in the post-hydrolysis state in myosin V. Conclusion: Mg2+ alters contractile velocity without altering overall tension-generating capacity. Significance: Mg2+-dependent regulation of motor activity is conserved in myosin motors. We examined the magnesium dependence of five class II myosins, including fast skeletal muscle myosin, smooth muscle myosin, β-cardiac myosin (CMIIB), Dictyostelium myosin II (DdMII), and nonmuscle myosin IIA, as well as myosin V. We found that the myosins examined are inhibited in a Mg2+-dependent manner (0.3–9.0 mm free Mg2+) in both ATPase and motility assays, under conditions in which the ionic strength was held constant. We found that the ADP release rate constant is reduced by Mg2+ in myosin V, smooth muscle myosin, nonmuscle myosin IIA, CMIIB, and DdMII, although the ADP affinity is fairly insensitive to Mg2+ in fast skeletal muscle myosin, CMIIB, and DdMII. Single tryptophan probes in the switch I (Trp-239) and switch II (Trp-501) region of DdMII demonstrate these conserved regions of the active site are sensitive to Mg2+ coordination. Cardiac muscle fiber mechanic studies demonstrate cross-bridge attachment time is increased at higher Mg2+ concentrations, demonstrating that the ADP release rate constant is slowed by Mg2+ in the context of an activated muscle fiber. Direct measurements of phosphate release in myosin V demonstrate that Mg2+ reduces actin affinity in the M·ADP·Pi state, although it does not change the rate of phosphate release. Therefore, the Mg2+ inhibition of the actin-activated ATPase activity observed in class II myosins is likely the result of Mg2+-dependent alterations in actin binding. Overall, our results suggest that Mg2+ reduces the ADP release rate constant and rate of attachment to actin in both high and low duty ratio myosins.
Downregulated MicroRNA-200a in Meningiomas Promotes Tumor Growth by Reducing E-Cadherin and Activating the Wnt/β-Catenin Signaling Pathway

ABSTRACT Meningiomas, one of the most common human brain tumors, are derived from arachnoidal cells associated with brain meninges, are usually benign, and are frequently associated with neurofibromatosis type 2. Here, we define a typical human meningioma microRNA (miRNA) profile and characterize the effects of one downregulated miRNA, miR-200a, on tumor growth. Elevated levels of miR-200a inhibited meningioma cell growth in culture and in a tumor model in vivo. Upregulation of miR-200a decreased the expression of transcription factors ZEB1 and SIP1, with consequent increased expression of E-cadherin, an adhesion protein associated with cell differentiation. Downregulation of miR-200a in meningiomas and arachnoidal cells resulted in increased expression of β-catenin and cyclin D1 involved in cell proliferation. miR-200a was found to directly target β-catenin mRNA, thereby inhibiting its translation and blocking Wnt/β-catenin signaling, which is frequently involved in cancer. A direct correlation was found between the downregulation of miR-200a and the upregulation of β-catenin in human meningioma samples. Thus, miR-200a appears to act as a multifunctional tumor suppressor miRNA in meningiomas through effects on the E-cadherin and Wnt/β-catenin signaling pathways. This reveals a previously unrecognized signaling cascade involved in meningioma tumor development and highlights a novel molecular interaction between miR-200a and Wnt signaling, thereby providing insights into novel therapies for meningiomas.
Shaping the Archaeal Cell Envelope

Although archaea have a similar cellular organization as other prokaryotes, the lipid composition of their membranes and their cell surface is unique. Here we discuss recent developments in our understanding of the archaeal protein secretion mechanisms, the assembly of macromolecular cell surface structures, and the release of S-layer-coated vesicles from the archaeal membrane.
Dysregulation of Chemokine/Chemokine Receptor Axes and NK Cell Tissue Localization during Diseases

Chemokines are small chemotactic molecules that play key roles in physiological and pathological conditions. Upon signaling via their specific receptors, chemokines regulate tissue mobilization and trafficking of a wide array of immune cells, including natural killer (NK) cells. Current research is focused on analyzing changes in chemokine/chemokine receptor expression during various diseases to interfere with pathological trafficking of cells or to recruit selected cell types to specific tissues. NK cells are a heterogeneous lymphocyte population comprising several subsets endowed with distinct functional properties and mainly representing distinct stages of a linear development process. Because of their different functional potential, the type of subset that accumulates in a tissue drives the final outcome of NK cell-regulated immune response, leading to either protection or pathology. Correspondingly, chemokine receptors, including CXCR4, CXCR3, and CX3CR1, are differentially expressed by NK cell subsets, and their expression levels can be modulated during NK cell activation. At first, this review will summarize the current knowledge on the contribution of chemokines to the localization and generation of NK cell subsets in homeostasis. How an inappropriate chemotactic response can lead to pathology and how chemokine targeting can therapeutically affect tissue recruitment/localization of distinct NK cell subsets will also be discussed.
Youth Civic Engagement in the United States: Understanding and Addressing the Impact of Social Impediments on Positive Youth and Community Development

The topic of civic engagement has come to the forefront of many recent discussions about the positive and healthy development of youth. Researchers and practitioners writing about youth civic engagement agree that civic engagement has short- and long-term benefits for youth and for society. These benefits have been discussed in terms of youth psychological well-being, academic achievement, and contributions to the social and political fabric of the country, including the promotion of civil society. Despite the general support across the past few decades for civic endeavors involving young people, such support has been largely absent for youth living in communities deprived of opportunities for civic experience or composed of critical masses of youth and adults willing to become civically engaged. This article discusses the benefits of youth civic engagement for youth and societies and the nature and role of contemporary social impediments to youth civic engagement in the United States.
Optimally Anonymous and Transferable Conditional E-cash

Transferable conditional electronic-cash (e-cash) allows a payer to spend an e-cash based on the outcome not known in advance. It also allows a payee to spend the e-cash to others, or deposit the e-cash to a bank based on the future outcome. Among security properties, the anonymity of the payer has been widely studied. However, the payer is linkable in the existing conditional e-cash schemes. This paper presents the rst optimally anonymous and transferable conditional electronic-cash (e-cash) system based on two recent cryptographic primitives, i.e., the Groth-Sahai(GS) proof system and the commuting signatures, to obtain the user's unlinkability and optimal anonymity. A publisher is introduced to publish the conditions, and is rstly for- malized. By dividing the deposit protocol into two parts, the anonymity of the user is obtained in the deposit protocol. Compared with the existing conditional e-cash schemes, this scheme has the constant size for the computation and communication. Finally, we give the security proof in the standard model.
Intersonic shear cracks and fault ruptures

Recent experimental observations of intersonic shear rupture events that occur in a variety of material systems have rekindled interest in the intersonic failure phenomenon. Since the early 1990s, engineers and scientists working in all length scales, from the atomistic, the structural, all the way up to the scale of the earth's deformation processes, have undertaken joint efforts to study this unexplored area of fracture mechanics. The analysis in the present article emphasizes the cooperative and complementary manner in which experimental observations and analytical and numerical developments have proceeded. The article first reviews early contributions to the theoretical literature of dynamic subsonic and intersonic fracture and highlights the significant differences between tensile and shear cracks. The article then uses direct laboratory observations as a framework for discussing the physics of intersonic shear rupture occurring in constitutively homogeneous (isotropic and anisotropic) as well as in inhomogeneous systems, all containing preferable crack paths or faults. Experiments, models, and field evidence at a variety of length scales (from the atomistic, the continuum, and up to the scale of geological ruptures) are used to discuss processes such as (1) shock wave formation, (2) large-scale frictional contact and sliding at the rupture faces, and (3) maximum attainable rupture speeds and rupture speed stability. Particular emphasis is given to geophysical field evidence and to the exploration of the possibility of intersonic fault rupture during shallow crustal earthquake events.
Social Class and Inequalities in Early Cognitive Scores

Research emphasising the importance of parenting behaviours and aspirations for child outcomes has been seized on by policymakers to suggest the responsibility of the worst off themselves for low levels of social mobility. This article provides a critique of the way in which research evidence has been used to support the dominant policy discourse in this area, as well as an empirical analysis. We use the Millennium Cohort Study to interrogate the relationship between social class and attainment in the early years of schooling. We investigate the extent to which social class inequalities in early cognitive scores can be accounted for by parental education, income, family social resources and parental behaviours. We conclude that social class remains an important concept for both researchers and policymakers, and that the link between structural inequalities and inequalities in children’s cognitive scores cannot be readily accounted for in terms of individual parenting behaviours.
A quantitative comparison of parallel computation models

This paper experimentally validates performance related issues for parallel computation models on several parallel platforms (a MasPar NIP-1 with 1024 processors, a 64-node GCel and a CM-5 of 64 processors). Our work consists of three parts. First, there is an evaluation part in which we investigate whether the models correctly predict the execution time of an algorithm implementation. Unlike previous work, which mostly demonstrated a close match between the measured and predicted running times, this paper shows that there are situations in which the models do not precisely predict the actual execution time of an algorithm implementation. Second, there is a comparison part in which the models are contrasted with each other in order to determine which model induces the fastest algorithms. Finally, there is an eficiency validation part in which the performance of the model derived algorithms are compared with the performance of highly optimized library routines to show the effectiveness of deriving fast algorithms through the formalisms of the models.
From Kidd to Dewey: the origin and meaning of ‘social efficiency’

Contemporary historians of education associate the term ‘social efficiency’ with a group of US educators who, in the 1910s and 1920s, aimed at creating a technocratic school and a conservative society of social stability and harmony. However, an investigation of the origin of the term indicates that ‘social efficiency’ began its career in 1894 in the UK with the writing of Benjamin Kidd. From the outset, Kidd’s social Darwinist position was disputed by sociologists and philosophers who interpreted the term from a humanitarian point of view. It was the broad, liberal approach inspired by John Hobson, Lester Ward, and John Dewey—and not the narrow, utilitarian approach propagated by David Snedden—that educators took up when they employed the term ‘social efficiency’ to define the main aim of education.
The lived experience of students with an invisible disability at a Canadian university

University institutions are required by law to make their services accessible to students with disabilities. Canadian universities have gone a long way to eliminate the physical obstacles that present barriers for students. Many students with disabilities have invisible disabilities that require different types of adjustments. Although some researchers have evaluated the needs of students with disabilities in higher education, the unique needs of students with invisible disabilities have received less attention. The best means of assessing these needs is through direct consultation with students with disabilities. Thus, in-depth interviews were conducted with university students with dyslexia, attention-deficit hyperactivity disorder, and mental illness. Themes were developed that related to the nature of the disability, the accessibility of the university context, the social and organizational barriers, and recommendations for change. This research lends insight into how individuals with invisible disabilities believe that they are perceived within the university context.
Lexicography and cognitive linguistics

The lexicon of a language is not an unstructured list of words. In this paper, we exemplify some of the basic conceptual structures that cognitive linguists work with and we discuss their potential applications to lexicographic work. Specifically, we focus on the possible advantages of using cognitive linguistics as a theoretical background in the structuring of entries, meanings, and idioms in dictionaries. In connection with these organizational issues, we discuss the knowledge-based organization of the mental lexicon (known as conceptual frames), and a type of organization of the mental lexicon that seems to be much more characteristic of Hungarian than of English: organization according to certain “root morphemes. ” We also deal with the conceptualization of an element within a topic area through another element within the same topic area (known as conceptual metonymy), the conceptualization of a topic area in terms of another topic area (known as conceptual metaphor); and the internal organization of the various senses of a word-concept (known as polysemy). We devote a section to idioms and their role as well as possible arrangement in the dictionary. Such thematic structures have, on the whole, remained outside the focus of everyday lexicographic practice. Here, we hope to demonstrate their importance and usefulness.
MULTIMODAL DISCOURSE MODELLING IN A MULTI-USER MULTI-DOMAIN ENVIRONMENT 1

This paper describes the discourse component of GALAXY , a multi-domain, multimodal conversational system. In designing this module, we are attempting to develop domain-independent mechanisms, controlled via declarative tables, to promote convenient instantiation of a discourse component for each new domain. Direct anaphoric reference as well as elliptical reference are dealt with appropriately. Users can also refer verbally to items selected via mouse clicks. Cross domain references are particularly challenging, as is the ambiguity problem arising from different case roles for different subdomains. Users often utter fragments, sometimes in response to server-initiated dialogue exchanges, so an extensive fragment interpretation mechanism is supported.
Reliability considerations in mobile devices

The problem of reliability in current chips has been the subject of numerous researchers. Mobile devices, commonly used in multimedia communications require low power during both normal operation and testing. In this paper a novel algorithm is presented for embedding test sets containing don't care values into sequences generated by binary counters. Therefore, both test time and power consumed during testing of the chips can be considerably reduced.
A Model of Factors Contributing to STEM Learning and Career Orientation

The purpose of this research was to develop and test a model of factors contributing to science, technology, engineering, and mathematics (STEM) learning and career orientation, examining the complex paths and relationships among social, motivational, and instructional factors underlying these outcomes for middle school youth. Social cognitive career theory provided the foundation for the research because of its emphasis on explaining mechanisms which influence both career orientations and academic performance. Key constructs investigated were youth STEM interest, self-efficacy, and career outcome expectancy (consequences of particular actions). The study also investigated the effects of prior knowledge, use of problem-solving learning strategies, and the support and influence of informal educators, family members, and peers. A structural equation model was developed, and structural equation modeling procedures were used to test proposed relationships between these constructs. Results showed that educators, peers, and family-influenced youth STEM interest, which in turn predicted their STEM self-efficacy and career outcome expectancy. STEM career orientation was fostered by youth-expected outcomes for such careers. Results suggest that students’ pathways to STEM careers and learning can be largely explained by these constructs, and underscore the importance of youth STEM interest.