Miracle-dz/UniFAR-FTUs huggingface dataset:
Social work with single fathers and non-resident fathers: How inclusive is our practice and where do we go from here?

This chapter is focused upon social work with single and non-resident fathers. There is a dearth of social work research that explores the experiences of single or non-resident fathers’ with social work, so this chapter starts to explore how we can work more sensitively and collaboratively with both groups. Both single and non-resident fatherhood raise challenges for socially constructed gendered norms, hegemonic masculinity and how children and families social work is practiced. Concepts of borderwork and the emotional regime are applied to develop understanding of these fathers’ experiences with social work and how practice can change. The chapter is located within wider discourses about the feminised role of caring and increasingly bureaucratic and authoritarian social work systems. Key practice features of assessment and engagement are discussed and suggestions for developing and improving practice are tentatively made.
Case report: A novel CACNA1S mutation associated with hypokalemic periodic paralysis

Background Hypokalemic periodic paralysis (HypoKPP) is a rare neuromuscular genetic disorder causing recurrent episodes of flaccid paralysis. Most cases are associated with CACNA1S mutation, causing defect of calcium channel and subsequent impairment of muscle functions. Due to defined management approaches early diagnosis is crucial for promptly treatment and prevention new attacks. Materials and methods We report a case of HypoKPP associated with previously unreported mutation in CACNA1S gene (p.R900M). Molecular modeling of CaV1.1 was applied to evaluate its pathogenicity. Results As a patient referred between attacks neurological status, laboratory and neurophysiological examination were unremarkable. Molecular modeling predicted that the p.R900M mutation affects the process of calcium channels activation. Conclusion Novel CACNA1S mutation, associated with HypoKPP was identified. Monte-Carlo energy minimization of the CaV1.1 model supported the association of this mutation with this disease.
Documenting past South American camelid diversity at Telarmachay (Puna of Junín, Peru) using first phalanges morphometrics

To get insights into the elusive process of the domestication of South American Camelids (SAC), we focused on the Central Andean zone and the long sequence from Telarmachay (Puna of Junín, Peru), for which an early process of domestication, dating 5500-5000 BP, has been proposed. We explored the camelid diversity of Telarmachay with a morphometric approach using modern guanaco and vicuña first phalanges. Our results support the previous identification of both wild camelids and indicated hunting practices. They also suggest earlier camelid anthropic control based on the occurrence of intermediate sized specimens. However, Telarmachay camelids require further investigated using a more powerful approach to access reliable proxies of changes in locomotor behaviors.
Field test of spectral line intensity parameters for tropospheric water vapor

[1] We report the results of a field experiment designed to study atmospheric water vapor absorption in the visible and near-infrared spectral regions between 550 and 1000 nm. We carried out spectroscopic ground measurements of direct solar radiation under clear-sky conditions in Boulder, Colorado. The data with a spectral resolution of approximately 1 nm were analyzed using the differential optical absorption spectroscopy (DOAS) technique in five different absorption bands of water vapor. We show that this technique can reveal the broadband effects of errors and inconsistencies in absorption spectra information for the water molecule. Retrievals of column tropospheric water vapor from the field spectra were compared to simultaneous independent estimates from Global Positioning System (GPS) data and radiosonde soundings. The data set is used to critically assess the widely used High-Resolution Transmission Molecular Absorption Database (HITRAN) [Rothman et al., 1998]. The results indicate that line intensities in the 3ν + δ polyad centered at 820 nm are underestimated by 21% with respect to the strong 3ν polyad centered at 940 nm, while the 4ν polyad at 720 nm shows agreement within the measurement accuracy of 3%. Two weaker bands centered at 650 and 590 nm were found to be overestimated by about 8–10%. The effect of the proposed corrections on the absorption of incoming solar flux for a clear-sky atmosphere is estimated to be 0.6 W/m2 for an overhead Sun.
Gendered Risk Engagement: Challenging the Embedded Vulnerability, Social Norms and Power Relations in Conventional Australian Bushfire Education

Building on an identified need for gender-sensitive approaches to bushfire risk engagement, this paper examines outreach initiatives specifically targeting women’s bushfire awareness and preparedness in southeast Australia. The results of an online survey, together with two workshops with community engagement staff and volunteers from rural fire services, convey perceived aids and obstacles for engaging women. Efforts at engaging women with bushfire risk management are shown to align squarely with efforts to create a more gender-balanced and gender-sensitive environment for bushfire brigade volunteers. The paper demonstrates how gender roles and gendered norms are reinforced by the patriarchal structures that shape everyday life and the on-the-ground application of official outreach policy and practice. This, in turn, results in heightened dimensions of gendered vulnerability to bushfire. Three key pointers to more successful engagement emerge from the analysis: the benefits of hands-on experience and practice, the strength of networks and the imperative of supportive learning environments.
STUDIES ON GENETIC VARIABILITY IN RICE

Genetic divergence was assessed in 32 varieties of rice (Oryza sativa L.) using u statis tic for six characters related to yield. The population was grouped into nine clusters. Tho geographic distribution was not related to genetic diversity. Genotypes chosen from the same eco-geographic region were found scattered in different clusters. tetra-cluster 0 value was highest for cluster V. Maximum intercluster D value was observed between clusters I and IX. Cluster i, had high mean value for panicle bearing tilles, cluster V for grains) panicle and grain yield/plant, and cluster VI for panicle length. The cluster Vil had the lowest mean for sterile grains/panicle, Plant height contributed Maximum role in total genetic diversity followed by sterile grains and grains/panicle, utilizing the genotypes of clusters which are highly divergent is likely to result in wide spectrum or variabilty through hybridization.
Regional and Racial Disparity of Preterm Birth Prevalence in Georgia, 1995–2012

Preterm birth (PTB), defined as a live birth with a gestational age of less than 37 weeks, is the leading cause of infant mortality in developed countries. Recent studies have shown increases in PTB rates through the 1990s and 2000s in the United States, especially in a few states in the southeast including Georgia. Although researchers have studied the epidemiology of PTB in several regions, the spatial-temporal patterns of PTB rates in Georgia remain largely unexplored. This paper examines the spatial variations of PTB prevalence in Georgia at the county level between 1995 and 2012. Spatial clusters are assessed using global Moran's I and local indicators of spatial association (LISA). For disparity analysis, comparisons are made between births classified by race (black vs. white) and by four levels of urbanization. Results indicated a steady increase in PTB rates for both black and white births of all four urbanization classifications from 1995 to 2007, followed by a general decline from 2007 to 2012 for all groups. More urbanized counties tended to have lower PTB rates than more rural counties when compared as groups. Spatial clustering of high PTB rates tended to occur in the southern portion of the state for both white and black births, growing more prominent in the south central region as time progressed. Alternatively, spatial clustering of low PTB rates tended to occur in counties located in the north and northeastern areas of Georgia. The findings from this exploratory research are expected to serve as the basis of further studies of PTB and its risk factors, as well as to more effectively allocating prenatal health care resources.
Integrative computational approach identifies new targets in CD4+ T cell-mediated immune disorders

CD4+ T cells provide adaptive immunity against pathogens and abnormal cells, and they are also associated with various immune related diseases. CD4+ T cells’ metabolism is dysregulated in these pathologies and represents an opportunity for drug discovery and development. Genome-scale metabolic modeling offers an opportunity to accelerate drug discovery by providing high-quality information about possible target space in the context of a modeled disease. Here, we develop genome-scale models of naïve, Th1, Th2 and Th17 CD4+ T cell subtypes to map metabolic perturbations in rheumatoid arthritis, multiple sclerosis, and primary biliary cholangitis. We subjected these models to in silico simulations for drug response analysis of existing FDA-approved drugs, and compounds. Integration of disease-specific differentially expressed genes with altered reactions in response to metabolic perturbations identified 68 drug targets for the three autoimmune diseases. In vitro experimental validations together with literature-based evidence showed that modulation of fifty percent of identified drug targets has been observed to lead to suppression of CD4+ T cells, further increasing their potential impact as therapeutic interventions. The used approach can be generalized in the context of other diseases, and novel metabolic models can be further used to dissect CD4+ T cell metabolism.
Genome-wide identification of the TCP gene family in Chrysanthemum lavandulifolium and its homologs expression patterns during flower development in different Chrysanthemum species

TCP proteins, part of the transcription factors specific to plants, are recognized for their involvement in various aspects of plant growth and development. Nevertheless, a thorough investigation of TCPs in Chrysanthemum lavandulifolium, a prominent ancestral species of cultivated chrysanthemum and an excellent model material for investigating ray floret (RF) and disc floret (DF) development in Chrysanthemum, remains unexplored yet. Herein, a comprehensive study was performed to analyze the genome-wide distribution of TCPs in C. lavandulifolium. In total, 39 TCPs in C. lavandulifolium were identified, showing uneven distribution on 8 chromosomes. Phylogenetic and gene structural analyses revealed that ClTCPs were grouped into classes I and II. The class II genes were subdivided into two subclades, the CIN and CYC/TB1 subclades, with members of each clade having similar conserved motifs and gene structures. Four CIN subclade genes (ClTCP24, ClTCP25, ClTCP26, and ClTCP27) contained the potential miR319 target sites. Promoter analysis revealed that ClTCPs had numerous cis-regulatory elements associated with phytohormone responses, stress responses, and plant growth/development. The expression patterns of ClTCPs during capitulum development and in two different florets were determined using RNA-seq and qRT-PCR. The expression levels of TCPs varied in six development stages of capitula; 25 out of the 36 TCPs genes were specifically expressed in flowers. Additionally, we identified six key ClCYC2 genes, which belong to the class II TCP subclade, with markedly upregulated expression in RFs compared with DFs, and these genes exhibited similar expression patterns in the two florets of Chrysanthemum species. It is speculated that they may be responsible for RFs and DFs development. Subcellular localization and transactivation activity analyses of six candidate genes demonstrated that all of them were localized in the nucleus, while three exhibited self-activation activities. This research provided a better understanding of TCPs in C. lavandulifolium and laid a foundation for unraveling the mechanism by which important TCPs involved in the capitulum development.
Modeling Coupled Hydromechanical Behavior of Landfilled Waste in Bioreactor Landfills: Numerical Formulation and Validation

AbstractBioreactor landfills involving leachate recirculation are emerging as the preferred option for managing municipal solid waste (MSW). Effective bioreactor landfill performance can be achieved by ensuring uniform and adequate moisture (leachate) distribution in landfilled MSW. This paper presents a numerical two-phase flow model as a tool to predict hydraulic behavior (moisture distribution and pore fluid pressures) in unsaturated MSW under leachate recirculation, mechanical response (stress-strain behavior), and coupled hydromechanical interactions of MSW in landfills. The selected mathematical model is the Fast Lagrangian Analysis of Continua (FLAC), which assumes leachate and landfill gas as two immiscible phases. The governing equations and numerical implementation are presented along with the general model implementation considerations. The model is validated by simulating the published laboratory studies, field studies, and published modeled studies. Overall, it is shown that the mathematical .
Design and Fabrication of a New Filament, PLA with PTFE as Fillers, for Water Repellent Surfaces

The use of additive manufacturing by fused deposition is a versatile, cost-effective and simple prototyping and manufacturing technique that is generating and accelerating a revolution in equipment and filaments. However, materials are limited to a small number of polymers. It is a scientific challenge to bring new characteristics and properties to the parts obtained. In this work, a new filament has been designed with the combination of PLA (poly lactic acid) as matrix and PTFE (polytetrafluoroethylene) as filler. This filament has improved the water repellency of the parts obtained. Cleaning, demoulding, anti-adherence, anti-frost, anti-humidity and anti-bacterial applications can be deployed with this new filament. Extruded filaments have been obtained with PLA beads and PTFE micropowder. Flat test tubes have been produced with this filament. The experiments included PTFE fillers (1% to 40% by weight). The surfaces have been characterised by sliding angle (SA) and static contact angle (CA) tests, surface roughness (Sa and Sz), flatness error and % water adsorption. The results indicate, as expected, that the higher the fluoropolymer content, the higher the hydrophobicity, reaching values of 125° for CA and 9° for SA, and the % adsorption decreases. In terms of roughness, the surfaces are less rough when the PTFE load increases. On the other hand, the flatness is a property strongly affected by the % PTFE load and at values higher than 15% it produces intense warping and deformation of the specimens. Finally, the PTFE loading thresholds in the PLA matrix have been obtained below which the wettability and dimensional reproduction properties are balanced and optimal.
Alpha/beta-gamma decoupling in methylphenidate medicated ADHD patients

There is much interest to understand how different neural rhythms function, interact and are regulated. Here, we focus on WM delay gamma to investigate its coupling with alpha/beta rhythms and its neuromodulation by methylphenidate. We address this through the use of human EEG conducted in healthy and ADHD subjects which revealed ADHD-specific electrophysiological deficits and MPH-induced normalization of gamma amplitude and its coupling with alpha/beta rhythms. Decreased alpha/beta-gamma coupling is known to facilitate memory representations via disinhibition of gamma ensembles coding the maintained stimuli. Here, we present EEG evidence which suggests that these dynamics are sensitive to catecholaminergic neuromodulation. MPH decreased alpha/beta-gamma coupling and this was related to the increase in delay-relevant gamma activity evoked by the same drug. These results add further to the neuromodulatory findings that reflect an electrophysiological dimension to the well-known link between WM delay and catecholaminergic transmission.
1-km-resolution land surface analysis over Japan: Impact of satellite-derived solar radiation

: Recent advances in remote-sensing technology have enabled estimation of surface solar radiation, which is an important input for land surface models (LSMs). This study investigates the impacts of satellite-derived solar radiation on an LSM by performing sensitivity experiments with and without a satellite-derived solar radiation product known as “EXAM”. Using the LSM “SiBUC-SIMRIW”, land surface analyses over Japan at a 1-km resolution were performed, comparable to observations from flux towers. We demonstrate that using the EXAM solar radiation improves not only the net solar radiation analyses, but also the analyses of net long-wave radiation, sensible heat flux, and latent heat flux at four ground observation sites. This suggests that using the satellite-derived EXAM solar radiation improves the three main budgets, i.e., radiation, heat and water budgets, of the land surface simulation. The findings demonstrate consistent improvements, therefore, SiBUC-SIMRIW-based land surface analyses can be expected to be improved using EXAM. The sensitivity experiments over Japan demonstrate that the change in solar radiation inputs largely affects the simulated sensible and latent heat fluxes. A relatively large change in surface runoff is evident in heavy snowfall regions in winter, which could be caused by a change in the snow melting period.
Evaluation of Removable Partial Denture Metal Frameworks Produced by Digital Methods—A Systematic Review

(1) Introduction: This review aimed to synthesize the significant literature addressing digital techniques for producing removable partial denture (RPD) metal frameworks, focusing on oral fit outcomes. (2) Material and Methods: A systematic review of the Web of Science and Pubmed databases was performed according to PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-analyses) guidelines. The selection was for original articles in English containing relevant data on RPD metal frameworks produced with digital techniques, including study characteristics, digital techniques, and fit assessment methods and outcomes. (3) Results: From the 967 search studies, 405 were duplications, and 521 were excluded after screening against set criteria. A manual search included 21 studies resulting in 62 papers for review. Extra-oral was more frequently used than intra-oral scanning. The computer-assisted design was the most applied digital technique. Additive manufacturing was preferred to milling for direct and indirect fabrication of frameworks. Fit assessments were based on qualitative measures, but quantitative evaluation showed acceptable clinical fit for RPDs made by digital protocols. (4) Conclusions: The combination of direct metal additive manufacturing with conventional impression was the most used protocol and included better qualitative and quantitative fit outcomes than the other digital protocols.
Three‐dimensional distribution of a major desert dust outbreak over East Asia in March 2008 derived from IASI satellite observations

We describe the daily evolution of the three‐dimensional (3D) structure of a major dust outbreak initiated by an extratropical cyclone over East Asia in early March 2008, using new aerosol retrievals derived from satellite observations of IASI (Infrared Atmospheric Sounding Interferometer). A novel auto‐adaptive Tikhonov‐Phillips‐type approach called AEROIASI is used to retrieve vertical profiles of dust extinction coefficient at 10 µm for most cloud‐free IASI pixels, both over land and ocean. The dust vertical distribution derived from AEROIASI is shown to agree remarkably well with along‐track transects of CALIOP spaceborne lidar vertical profiles (mean biases less than 110 m, correlation of 0.95, and precision of 260 m for mean altitudes of the dust layers). AEROIASI allows the daily characterization of the 3D transport pathways across East Asia of two dust plumes originating from the Gobi and North Chinese deserts. From AEROIASI retrievals, we provide evidence that (i) both dust plumes are transported over the Beijing region and the Yellow Sea as elevated layers above a shallow boundary layer, (ii) as they progress eastward, the dust layers are lifted up by the ascending motions near the core of the extratropical cyclone, and (iii) when being transported over the warm waters of the Japan Sea, turbulent mixing in the deep marine boundary layer leads to high dust concentrations down to the surface. AEROIASI observations and model simulations also show that the progression of the dust plumes across East Asia is tightly related to the advancing cold front of the extratropical cyclone.
Séquence de la transition Illinoien–Sangamonien : forage IAC-91 de l'île aux Coudres, estuaire moyen du Saint-Laurent, Québec

A series of Pleistocene deposits extending over 155 m below sea level was drilled at Aux Coudres Island, in the middle St. Lawrence Estuary, Quebec. The series, which basis is unknown, is divided into two sedimentary units: the lower Baie-Saint-Paul Glacial Complex facies (−155 to −125 m), which is correlated with the Illinoian (isotopic stage 6), and a stratified sequence referred to as the ile aux Coudres Formation. The latter is subdivided into four zones: a very compact lower clay (−125 to −102 m), rhythmites with Paleozoic schist debris (−102 to −71 m), and prodeltaic silts and deltaic sandy silts with brackish water benthic foraminifera (−71 to −2 m). The spore and pollen content indicates a schrub tundra followed by an afforestation sequence of a boreal forest that changes to an Abies forest and then to an interglacial mixed forest with Betula , Jugions , Carpinus or Ostrya , Carya , and, at the top, Betula , Tsuga , Quercus , and Ulmus . The accumulation of the sediments of the Ile aux Coudres Formation required approximately 3500 years, beginning with a deep marine environment (about 300 m) followed by shallowing waters during the subsequent glacioisostatic rebound phase of the regression. The sedimentation is assigned to a main postglacial marine invasion, referred to as the Guettard Sea, which occurred prior to two regional glacial episodes and was partly contemporaneous with Bell Sea invasion in the Hudson Bay lowlands. A major postglacial sedimentary influx in the Atlantic Ocean, during the Illinoian-Sangamonian transition and at the beginning of the Sangamonian (transition 6–5 and early substage 5e) is inferred from this marine event.