Miracle-dz/UniFAR-FTUs huggingface dataset:
Integrative Neuroscience Original Research Article Neural Underpinnings of Distortions in the Experience of Time across Senses

Auditory signals (A) are perceived as lasting longer than visual signals (V) of the same physical duration when they are compared together. Despite considerable debate about how this illusion arises psychologically, the neural underpinnings have not been studied. We used functional magnetic resonance imaging (fMRI) to investigate the neural bases of audiovisual temporal distortions and more generally, intersensory timing. Adults underwent fMRI while judging the relative duration of successively presented standard interval–comparison interval (CI) pairs, which were unimodal (A–A, V–V) or crossmodal (V–A, A–V). Mechanisms of time dilation and compression were identified by comparing the two crossmodal pairs. Mechanisms of intersensory timing were identified by comparing the unimodal and cross-modal conditions.The behavioral results showed that auditory CIs were perceived as lasting longer than visual CIs.There were three novel fMRI results. First, time dilation and compression were distinguished by differential activation of higher-sensory areas (superior temporal, posterior insula, middle occipital), which typically showed stronger effective connectivity when time was dilated (V–A). Second, when time was compressed (A–V) activation was greater in frontal cognitive-control centers, which guide decision making. These areas did not exhibit effective connectivity. Third, intrasensory timing was distinguished from inter-sensory timing partly by decreased striatal and increased superior parietal activation.These regions showed stronger connectivity with visual, memory, and cognitive-control centers during intersensory timing. Altogether, the results indicate that time dilation and compression arise from the connectivity strength of higher-sensory systems with other areas. Conversely, more extensive network interactions are needed with core timing (striatum) and attention (superior parietal) centers to integrate time codes for intersensory signals.
Substitution rates of video consultations for traditional consultations at a tertiary public hospital

Using a case study approach, we conducted a retrospective review of 12 months of outpatient activity at the Princess Alexandra Hospital (PAH) in Brisbane, Australia. From our dataset we calculated two variables – the telehealth-eligible substitution rate and the overall telehealth substitution rate. Telehealth eligibility is specialty-specific and is based on clinical and geographical constraints. During the study period there were video consultations (N = 1088) and traditional consultations (N = 41,951). The telehealth-eligible and overall substitution rates were 17.5% and 2.5%, respectively. The overall telehealth substitution rate is substantially lower than the telehealth-eligible substitution rate. This is due to the majority of patients being from local catchment areas which are currently ineligible for video consultations at the PAH. The highest observed overall telehealth substitution rate was for the radiosurgery which had telehealth activity as a reportable key performance indicator since inception of the service, which may have contributed to the relatively high rate. In-home video consultations with patients who reside in metropolitan areas are needed to substantially increase the rate of telehealth substitution.
Vector Control of Double Excited Synchronous Machine as Integrated Starter-Alternator

The paper proposes a double excited synchronous machine as integrated starter-alternator for future automobiles applications. Particularly, the biaxial excitation synchronous machine (BESM) is proposed for its high efficiency and wide constant power speed range. As the integrated starter-alternator system combines both starter and generator functions in a single electric machine, an alternative vector control strategy for BESM is developed and detailed to allow operation in the two modes at unity power factor operation by setting d-axis current to be zero and q-axis current to be constant and equal to its value that cancel the q-axis flux. In such conditions, the BESM torque can be controlled by the dc-excitation current and the required dc-bus voltage can be regulated within the 42V PowerNet specifications. To overcome the slowness dc-excitation current response, which is due to higher dc-field excitation time constant, and to increase the torque response quickness, the control of the magnetising current is proposed instead of the d-axis current. Implementation and simulation results validate the proposed scheme and provide a practical solution for an integrated starter-alternator.
Fast Agglomerative Clustering Using a k-Nearest Neighbor Graph

We propose a fast agglomerative clustering method using an approximate nearest neighbor graph for reducing the number of distance calculations. The time complexity of the algorithm is improved from O(tauN2) to O(tauN log N) at the cost of a slight increase in distortion; here, tau denotes the lumber of nearest neighbor updates required at each iteration. According to the experiments, a relatively small neighborhood size is sufficient to maintain the quality close to that of the full search
Vaccines for Tuberculosis: Novel Concepts and Recent Progress

SUMMARY Three-quarters of a century after the introduction of Mycobacterium bovis BCG, the first tuberculosis vaccine, new vaccines for tuberculosis are finally entering clinical trials. This breakthrough is based not only on advances in proteomics and genomics which have made the construction of new vaccines possible, but also on a greatly expanded knowledge of the immunology of tuberculosis. Here we review our current understanding of how Mycobacterium tuberculosis subverts or survives the host's immune response to cause disease and why the current vaccination strategy, which relies on BCG, is only partially successful in countering the pathogen. This provides a background for describing the new generation of vaccines designed to supplement or replace the current vaccine and the different approaches they take to stimulate immunity against M. tuberculosis.
A temporal paraconsistent relational algebra for incomplete and inconsistent information

We construct a framework for natural handling of incomplete and inconsistent information in temporal databases. Central to this framework are structures that we call time-varying paraconsistent relations, which are essentially 4-valued relations that vary over time. For such structures, we present an algebra based on temporal semantics in which there is no explicit manipulation of time indices, yet it is rich enough to express recursive equations as queries. The algebra is a consistent extension of the relational algebra; it supports basic algebraic equivalences, and has a well-defined formal semantics. We also provide many examples of queries expressed in this algebra. To our knowledge, our framework is the first treatment of inconsistent information in the context of temporal databases.
Efficient Online Inference for Infinite Evolutionary Cluster models with Applications to Latent Social Event Discovery

The Recurrent Chinese Restaurant Process (RCRP) is a powerful statistical method for modeling evolving clusters in large scale social media data. With the RCRP, one can allow both the number of clusters and the cluster parameters in a model to change over time. However, application of the RCRP has largely been limited due to the non-conjugacy between the cluster evolutionary priors and the Multinomial likelihood. This non-conjugacy makes inference di cult and restricts the scalability of models which use the RCRP, leading to the RCRP being applied only in simple problems, such as those that can be approximated by a single Gaussian emission. In this paper, we provide a novel solution for the non-conjugacy issues for the RCRP and an example of how to leverage our solution for one speci c problem - the social event discovery problem. By utilizing Sequential Monte Carlo methods in inference, our approach can be massively paralleled and is highly scalable, to the extent it can work on tens of millions of documents. We are able to generate high quality topical and location distributions of the clusters that can be directly interpreted as real social events, and our experimental results suggest that the approaches proposed achieve much better predictive performance than techniques reported in prior work. We also demonstrate how the techniques we develop can be used in a much more general ways toward similar problems.
Validation of Mobility Simulations via Measurement Drive Tests in an Operational Network

Simulations play a key role in validating new concepts in cellular networks, since most of the features proposed and introduced into the standards are typically studied by means of simulations. In order to increase the trustworthiness of the simulation results, proper models and settings must be provided as inputs to the simulators. It is therefore crucial to perform a thorough validation of the models used for generating results. The objective of this paper is to compare measured and simulated mobility performance results with the purpose of understanding whether simulation models are close to reality. The presented study is based on drive tests measurements and explicit simulations of an operator network in the city of Aalborg (Denmark) - modelling a real 3D environment and using a commonly accepted dynamic system level simulation methodology. In short, the presented results show that the simulated handover rate, location of handovers, radio link failures, and signal/interference level statistics match well with measurements, giving confidence that the simulations produce realistic performance results.
Spatial Modulation for 2 Generalized MIMO : Challenges , 3 Opportunities , and 4 Implementation

8 ABSTRACT | A key challenge of future mobile communication 9 research is to strike an attractive compromise between 10 wireless network’s area spectral efficiency and energy effi11 ciency. This necessitates a clean-slate approach to wireless 12 system design, embracing the rich body of existing knowledge, 13 especially on multiple-input–multiple-ouput (MIMO) technolo14 gies. This motivates the proposal of an emerging wireless 15 communications concept conceived for single-radio-frequency 16 (RF) large-scale MIMO communications, which is termed as SM. 17 The concept of SM has established itself as a beneficial 18 transmission paradigm, subsuming numerous members of the 19 MIMO system family. The research of SM has reached sufficient 20 maturity to motivate its comparison to state-of-the-art MIMO 21 communications, as well as to inspire its application to other 22 emerging wireless systems such as relay-aided, cooperative, 23 small-cell, optical wireless, and power-efficient communica24 tions. Furthermore, it has received sufficient research attention 25 to be implemented in testbeds, and it holds the promise of 26 stimulating further vigorous interdisciplinary research in the 27 years to come. This tutorial paper is intended to offer a 28 comprehensive state-of-the-art survey on SM–MIMO research, 29 to provide a critical appraisal of its potential advantages, and to 30 promote the discussion of its beneficial application areas and 31 their research challenges leading to the analysis of the 32 technological issues associated with the implementation of 33 SM–MIMO. The paper is concluded with the description of the 34 world’s first experimental activities in this vibrant research 35 field.
Visual servoing of constrained differential-drive mobile robots using robust tube-based predictive control

This work proposes a control strategy for the vision-based control problem of a nonholonomic constrained differential-drive mobile robots with bounded disturbance by using robust tube-based model predictive control (MPC) method. The proposed Tube-based MPC approach introduces the state feedback controller into the nonlinear system to force the state variables to be constrained within an invariant designed tube and a nominal MPC is applied to stabilize the nominal system which is limited to the tighter constraint sets. Finally, extensive experimental results on stabilization control of the nonholonomic mobile robot are provided to verify the effectiveness of the proposed robust tuber-based MPC.
Thyroid cancer in the Pacific.

Affiliations of authors:A. L. Coker, Department of Epidemiology and Biostatistics, School of Public Health, University of South Carolina, Columbia; M. M. Crane (Research Epidemiologist), R. P. Sticca (Cancer Treatment Center), Greenville Hospital System, SC; D. W. Sepkovic, Strang-Cornell Cancer Center, New York, NY. Correspondence to: Ann L. Coker, Ph.D., Department of Epidemiology and Biostatistics, School of Public Health, University of South Carolina, Columbia, SC, 29208. Supported by Cooperative Agreement No. U48/ CCU409664-03 from the Centers for Disease Control and Prevention.
F-box protein FBXO31 is down-regulated in gastric cancer and negatively regulated by miR-17 and miR-20a

FBXO31, a subunit of the SCF ubiquitin ligase, played a crucial role in neuronal development, DNA damage response and tumorigenesis. Here, we investigated the expression and prognosis value of FBXO31 in human primary gastric cancer (GC) samples. Meanwhile, the biological role and the regulation mechanism of FBXO31 were evaluated. We found that FBXO31 mRNA and protein was decreased dramatically in the GC tissue compared with the adjacent non-cancerous tissues. FBXO31 expression was significantly associated with tumor size, tumor infiltration, clinical grade and patients' prognosis. FBXO31 overexpression significantly decreased colony formation and induced a G1-phase arrest and inhibited the expression of CyclinD1 protein in GC cells. Further evidence was obtained from knockdown of FBXO31. Ectopic expression of FBXO31 dramatically inhibited xenograft tumor growth in nude mice. miR-20a and miR-17 mimics inhibited, whereas the inhibitor of miR-20a and miR-17 increased, the expression of FBXO31, respectively. miR-20a and miR-17 directly bind to the 3'-UTR of FBXO31. The level of miR-20a and miR-17 in GC tissue was significantly higher than that in surrounding normal mucosa. Moreover, a highly significant negative correlation between miR-20a (miR-17) and FBXO31 was observed in these GC samples. Therefore, effective therapy targeting the miR-20a (miR-17)-FBXO31-CyclinD1 pathway may help control GC progression.
Alcohol in Australia : Issues and Strategies

The National Alcohol Strategy and its companion document 'Alcohol in Australia: Issues and Strategies' were endorsed by the Ministerial Council on Drug Strategy in July 2001. The documents were prepared for the Intergovernmental Committee on Drugs by members of the National Expert Advisory Committee on Alcohol (NEACA) with assistance from the NEACA project officer and secretariat. The Australian National Council on Drugs and a broad range of key stakeholders also contributed to the drafting of the documents.
HCI Research Issues in Electronic Commerce

This article outlines a number of important research issues in human-computer interaction in the e-commerce environment. It highlights some of the challenges faced by users in browsing Web sites and conducting searches for information, and suggests several areas of research for promoting ease of navigation and search. Also, it discusses the importance of trust in the online environment, describing some of the antecedents and consequences of trust, and provides guidelines for integrating trust into Web site design. The issues discussed in this article are presented under three broad categories of human-computer interaction – Web usability, interface design, and trust – and are intended to highlight what we believe are worthwhile areas for future research in e-commerce
Hybrid Fault Detection Technique: A Case Study on Virtex-II Pro's PowerPC 405

Hardening processor-based systems against transient faults requires new techniques able to combine high fault detection capabilities with the usual design requirements, e.g., reduced design-time, low area overhead, reduced (or null) accessibility to processor internal hardware. This paper proposes the adoption of a hybrid approach, which combines ideas from previous techniques based on software transformations with the introduction of an Infrastructure IP with reduced memory and performance overheads, to harden system based on the PowerPC 405 core available in Virtex-II Pro FPGAs. The proposed approach targets faults affecting the memory elements storing both the code and the data, independently of their location (inside or outside the processor). Extensive experimental results including comparisons with previous approaches are reported, which allow practically evaluating the characteristics of the method in terms of fault detection capabilities and area, memory and performance overheads
Ensemble kalman filter assimilation of doppler radar data with a compressible nonhydrostatic model : OSS experiments

Abstract A Doppler radar data assimilation system is developed based on an ensemble Kalman filter (EnKF) method and tested with simulated radar data from a supercell storm. As a first implementation, it is assumed that the forward models are perfect and that the radar data are sampled at the analysis grid points. A general purpose nonhydrostatic compressible model is used with the inclusion of complex multiclass ice microphysics. New aspects of this study compared to previous work include the demonstration of the ability of the EnKF method to retrieve multiple microphysical species associated with a multiclass ice microphysics scheme, and to accurately retrieve the wind and thermodynamic variables. Also new are the inclusion of reflectivity observations and the determination of the relative role of the radial velocity and reflectivity data as well as their spatial coverage in recovering the full-flow and cloud fields. In general, the system is able to reestablish the model storm extremely well after a num.
Norovirus GII.4 Strains and Outbreaks, Australia

To the Editor: Viral gastroenteritis affects millions of people of all ages worldwide, and some seasonality has been observed in outbreak occurrences (1–3). During early 2006 in New South Wales (NSW), a marked increase in outbreaks of gastroenteritis occurred (Figure): 155 outbreaks were reported during the first 5 months compared with 88 outbreaks during 2005. During the first 5 months of 2006, the Enteric Pathogens Laboratory–South Eastern Area Laboratory Services (EPL-SEALS) recorded an increase in norovirus in stool samples, detected by using an enzyme immunoassay (IDEIA Norovirus, DakoCytomation, Cambridgeshire, UK). From January through May 2006, the proportion of samples positive for norovirus increased successively: 0/47 (0%), 1/73 (1.4%), 5/169 (3.0%), 8/106 (7.5%), and 93/413 (22.5%). This trend followed the increasing reports of outbreaks made to the NSW Department of Health (Figure). In May, the rate of norovirus detection (22.5%) was significantly greater than that of any other pathogen (Fisher exact test, p<0.0001), including intestinal parasites, foodborne bacterial pathogens (Salmonella, Shigella, and Camplylobacter), and enteric viruses (rotavirus, adenovirus, and astrovirus).
Transcending the meat: immersive technologies and computer mediated bodies

In this paper we will call into question the philosophical grounding for the belief that our mind can in principle be removed from, or transcend, our bodies. We will show that modern immersive technology, such as virtual and web technologies, tacitly attempt to implement this philosophy. We will find that there is a growing community called the Transhumanists who are a loosely knit group of highly educated hi-tech professionals and scientists who explicitly accept the transcendent mind hypothesis. Through the work and influence of these professionals values that are antagonistic to the body enter, explicitly or tacitly, into computer technology. It is our claim that the transcendent mind hypothesis is in error and that immersive technologies have to take seriously issues regarding the embodied nature of their users and that this embodiment can not be transcended in any meaningful way.
Multirate interacting multiple model filtering for target tracking using multirate models

A multirate interacting multiple model (MRIMM) tracking algorithm has been developed. The algorithm is based on a reformulation of the interacting multiple model (IMM) filter under the assumption that each model operates at an update rate proportional to the model's assumed dynamics. A set of multirate models is derived based on the geometrical interpretation of a discrete wavelet transform. A wavelet transform is used to generate equivalent multirate measurements, which exhibit the additional property of lower equivalent measurement noise for low-rate data. Using this filtering approach, the MRIMM algorithm significantly outperforms a full-rate IMM filter when no manoeuvres occur and performs comparably with the IMM filter when manoeuvres occur, with a certain amount of computational savings. This approach also has the advantages of improved sensitivity for manoeuvre detection.