Miracle-dz/UniFAR-FTUs huggingface dataset:
Partial decode-forward binning for full-duplex causal cognitive interference channels

The causal cognitive interference channel (CCIC) is a four-node channel, in which the second sender obtains information from the first sender causally and assists in the transmission of both. We propose a new coding scheme called Han-Kobayashi partial decode-forward binning (HK-PDF-binning), which combines the ideas of Han-Kobayashi coding, partial decode-forward relaying, conditional Gelfand-Pinsker binning and relaxed joint decoding. The second sender decodes a part of the message from the first sender, then uses Gelfand-Pinsker binning to bin against the decoded codeword. When applied to the Gaussian channel, this HK-PDF-binning essentializes to a correlation between the transmit signal and the state, which encompasses the traditional dirty-paper-coding binning as a special case when this correlation factor is zero. The proposed scheme encompasses the Han-Kobayashi rate region and achieves both partial decode-forward relaying rate for the first user and interference-free rate for the second user.
A systematic review of NSAIDs withdrawn from the market due to hepatotoxicity: lessons learned from the bromfenac experience

Drug‐induced hepatotoxicity is the leading cause of acute liver failure (ALF) in the US and the most common adverse event causing drug non‐approval and drug withdrawal by the U.S. Food and Drug Administration (FDA). Three different nonsteroidal anti‐inflammatory drugs (NSAIDs) have been withdrawn in the UK and/or the US due to hepatotoxicity (bromfenac, ibufenac, and benoxaprofen). A systematic review of clinical trials data for these drugs was performed in an effort to identify possible early signals that could have predicted post‐marketing serious hepatoxicity. There were very limited published data on benoxaprofen and none on ibufenac or bromfenac. The publicly accessible archives of the FDA provided information on bromfenac. Flu‐like symptoms associated with hepatic enzyme elevation and a case of possible drug‐related hepatocellular jaundice may in retrospect have been signals for serious hepatotoxicity in the database of 1195 subjects reviewed by the FDA. Following approval, rates of acute liver failure for bromfenac were estimated to be in the range of 1:10 000.
Plasticity of Cells and Ex Vivo Production of Red Blood Cells

The supply of transfusable red blood cells (RBCs) is not sufficient in many countries. If transfusable RBCs could be produced abundantly from certain resources, it would be very useful. Our group has developed a method to produce enucleated RBCs efficiently from hematopoietic stem/progenitor cells present in umbilical cord blood. More recently, it was reported that enucleated RBCs could be abundantly produced from human embryonic stem (ES) cells. The common obstacle for application of these methods is that they require very high cost to produce sufficient number of RBCs that are applicable in the clinic. If erythroid cell lines (immortalized cell lines) able to produce transfusable RBCs ex vivo were established, they would be valuable resources. Our group developed a robust method to obtain immortalized erythroid cell lines able to produce mature RBCs. To the best of our knowledge, this was the first paper to show the feasibility of establishing immortalized erythroid progenitor cell lines able to produce enucleated RBCs ex vivo. This result strongly suggests that immortalized human erythroid progenitor cell lines able to produce mature RBCs ex vivo can also be established.
The Jefferson Scale of Empathy (JSE): An Update

Three versions of the JSE are available for administration to 1) physicians and other health providers, 2) medical students, and 3) students in the health professions other than medicine. The three versions are similar in content, with slight modifications in wording of some of the items to maintain face/content validity for the target populations. Other researchers have consulted with us and modified the scale for administration to groups such as pediatric nurses, psychotherapists, clinical social workers, counselors, dentists, veterinarians, ministers/ priests, and leaders/supervisors.
Ontological perspective in metamodeling for model transformations

Model Driven Engineering (MDE) aims to facilitate building larger and more complex, reliable software systems by introducing a higher abstraction level than the code level. The technical space concept discusses how the basic MDE principles may be mapped onto modern platform support and several technical spaces are proposed to support MDE. In this paper, we propose to use the ontology technical space in model transformations to achieve the targets of MDE. Using the ontology technical space will enable us to model not only the meta concepts but also the semantic context which can be used in model inferencing. Within this context, we define meta models of object oriented models ontologicaly.
Ontogeny of erythropoiesis

Purpose of reviewThe present study review examines the current understanding of the ontogeny of erythropoiesis with a focus on the emergence of the embryonic (primitive) erythroid lineage and on the similarities and differences between the primitive and the fetal/adult (definitive) forms of erythroid cell maturation. Recent findingsPrimitive erythroid precursors in the mouse embryo and cultured in vitro from human embryonic stem cells undergo ‘maturational’ globin switching as they differentiate terminally. The appearance of a transient population of primitive ‘pyrenocytes’ (extruded nuclei) in the fetal bloodstream indicates that primitive erythroblasts enucleate by nuclear extrusion. In-vitro differentiation of human embryonic stem cells recapitulates hematopoietic ontogeny reminiscent of the murine yolk sac, including overlapping waves of hemangioblast, primitive, erythroid, and definitive erythroid progenitors. Definitive erythroid potential in zebrafish embryos, like that in mice, initially arises prior to, and independent of, hematopoietic stem cell emergence in the region of the aorta. Maturation of definitive erythroid cells within macrophage islands promotes erythroblast–erythroblast and erythroblast–stromal interactions that regulate red cell output. SummaryThe study of embryonic development in several different model systems, as well as in cultured human embryonic stem cells, continues to provide important insights into the ontogeny of erythropoiesis. Contrasting the similarities and differences between primitive and definitive erythropoiesis will lead to an improved understanding of erythroblast maturation and the terminal steps of erythroid differentiation.
On Selective Result Merging in a Metasearch Enviroment

When a query is passed to multiple search engines, each search engine returns a ranked list of documents. The problem of metasearch is to fuse these ranked lists such that optimal performance is achieved because of the combination. There are two parts of the metasearch process. The first part is to select which search engine results are to be merged. The second part is the actual process of merging. In this paper we propose (1) a strategy for selective merging of results from a metasearch engine and (2) a heuristic for handling missing documents in result sets to be merged to improve the result-merging process Our experimental results will show that our proposed strategy for selection before merging coupled by incorporating it into the BORDA method improves the performance of merging.
Pacific Asia Conference on Information Systems ( PACIS ) 6-18-2013 Understanding Status Update in Microblog : A Perspective on Media Needs

Microblog has grown popularly as a seminal social medium for timely information seeking and sharing. However, the reason why individuals update real-time information in microblog has not been well understood, and empirical research to address this specific information behavior is hardly available. As a felt urge can be conceptualized as a precursor of real-time updating in the microblog, we attempt to capture the underlying mechanism in causing this less reflective behavior urge. We apply the media needs theory to investigate how the individuals’ media needs spark their urge to update personal status in the microblog. In particular, we conceptualize the cognitive needs as related to information uniqueness, personal integrative needs as related to connectivity, social integrative needs as a unidirectional relationship, affective needs as positive emotions and tension release needs as negative emotions. An online survey was employed to validate the proposed model within 523 microblog users in China. The results suggest that the users’ behavior urge is significantly influenced by information uniqueness, connectivity, unidirectional relationship and positive emotions. Furthermore, among the five media needs, the affective and social integrative related factors strongly determine the personal real-time status update in microblog. The theoretical and practical implications are discussed in this paper.
A Case Study in Multi-Sensory Investigation of Geoscientific Data

In this paper, we report our ongoing research into multi-sensory investigation of geoscientific data. Our Geoscientific Data Investigation System (GDIS) integrates three-dimensional, interactive computer graphics, touch (haptics) and real-time sonification into a multi-sensory Virtual Environment. GDIS has been used to investigate geological structures on the high-resolution bathymetry data from the Mid-Atlantic Ridge. Haptic force feedback was used to precisely digitize line features on three-dimensional morphology and to feel surface properties via varying friction settings; additional, overlapping data can be perceived via sound (sonification). We also report on the results of a psycho-acoustic study about the absolute recognition of sound signals, and on the actual feedback that we have received from a number of geoscientists during a recent major geoscience conference.
Cataract surgery: limitations and barriers in Makurdi, Benue State.

BACKGROUND Cataract is amenable to surgery; despite this affected patients do not always embrace or accept cataract surgical intervention. The study aims to ascertain the factors responsible for this negative attitude towards cataract surgery by affected patients. METHODS A prospective study was carried out with an interview assisted questionnaire, parameters assessed were duration of blindness before presentation, insight into the cause of cataract, awareness of the available treatment, knowledge of where to go for treatment and possible barriers to surgical treatment was administered to all consecutive patients aged 40 years and above whose cause of visual impairment and blindness is principally due to cataract for a period of one year (January 2007 December 2007). RESULTS Senile cataract constituted 2.6% (180) of all the patients aged 40 years and above. Duration of blindness before presentation ranged from 6 to 84 months. Majority of the patients (65%) were aware that surgical intervention was the answer to their visual dysfunction. CONCLUSION Although, affected patients are knowledgeable that surgical intervention was the answer to their visual dysfunction, they do not readily embrace surgical intervention for diverse reasons.
Pregnancy in women with chronic renal disease.

PREGNANCY in women with chronic renal disease is accompanied by an increase in such complications as hypertension and proteinuria and by increases in prematurity and fetal loss. Although fertility is decreased in women with advanced renal insufficiency, pregnancy sometimes occurs. Moreover, transplantation restores fertility to many women with end-stage renal disease. This article attempts to define some of the risks associated with pregnancy in women with renal disease and to offer guidelines for their care. Hypertension The problem that poses the greatest danger to the mother's life is severe hypertension, with its risk of central nervous system bleeding. Hypertension is .
Therapy of chemotherapy‐induced peripheral neuropathy

Chemotherapy‐induced peripheral neuropathy (CIPN) is still a common and disabling side effect of many chemotherapy agents in use today. Unfortunately, neither prophylactic strategies nor symptomatic treatments have proven useful yet. This review will discuss the diagnosis and evaluation of neuropathy in cancer patients, as well as reviewing the various prophylactic and symptomatic treatments that have been proposed or tried. However, sufficient evidence is lacking to recommend any of these treatments to patients suffering with CIPN. Therefore, the best approach is to treat symptomatically, and to start with broad‐spectrum analgesic medications such as non‐steroidal anti‐inflammatory drugs (NSAIDs). If NSAIDs fail, a reasonable second‐line agent in properly selected patients may be an opioid. Unfortunately, even when effective in other types of neuropathic pain, anti‐depressants and anticonvulsants have not yet proven effective for treating the symptoms of CIPN.
Recognition Algorithms for the Loom Classifier

Most of today's terminological representation systems implement hybrid reasoning architectures wherein a concept classifier is employed to reason about concept definitions, and a separate recognizer is invoked to compute instantiation relations between concepts and instances. Whereas most of the existing recognizer algorithms designed to maximally exploit the reasoning supplied by the concept classifier, LOOM has experimented with recognition strategies that place less emphasis on the classifier, and rely more on the abilities of LOOM'S backward chaining query facility. This paper presents the results of experiments that test the performance of the LOOM algorithms. These results suggest that, at least for some applications, the LOOM approach to recognition is likely to outperform the classical approach. They also indicate that for some applications, much better performance can be achieved by eliminating the recognizer entirely, in favor of a purely backward chaining architecture. We conclude that no single recognition algorithm or strategy is best for all applications, and that an architecture that offers a choice of inference modes is likely to be more useful than one that offers only a single style of reasoning.
Respiratory Modulation of Muscle Sympathetic Nerve Activity in Patients With Chronic Heart Failure

Background— Sympathoexcitation and respiratory instability are closely related to worsening of chronic heart failure. To elucidate the dynamic nature of respiratory modulation of sympathetic activity in patients with heart failure, we studied within-breath variation of muscle sympathetic nerve activity (MSNA) under various ventilatory volumes. Methods and Results— MSNA, blood pressure, and respiratory flow were recorded in 23 patients with left ventricular ejection fraction ≤45%. Within-breath suppression of MSNA (neural silence) was found in 11 patients (MSNA bursts: 71±10/100 heartbeats) but not in the remaining 12 patients (MSNA bursts: 88±8/100 heartbeats). Patients without neural silence had a smaller tidal volume (391±70 versus 267±75 mL/m2, P <0.01) and a higher respiratory rate (15±2 versus 19±4 breaths/min, P <0.01) during spontaneous respiration than those with neural silence. The relationship between tidal volume and minimal amplitude of MSNA bursts in each breath was obtained during random-interval breathing and fitted by an exponential function. The curve of patients without neural silence was shifted to the right and upward, which suggests that a greater tidal volume was required to suppress MSNA (227±70 versus 437±195 mL/m2, P <0.01). Conclusions— Sympathoexcitation in patients with chronic heart failure is closely related to both a decrease in resting tidal volume and an attenuated sympathoinhibitory effect of lung inflation reflex.
An Introduction to Description Logic

2 A Basic Description Logic 10 2.1 The concept language of the DL ALC 10 2.2 ALC knowledge bases 16 2.2.1 ALC TBoxes 17 2.2.2 ALC ABoxes 19 2.2.3 Restricted TBoxes and concept definitions 23 2.3 Basic reasoning problems and services 28 2.4 Using reasoning services 36 2.5 Extensions of the basic DL ALC 37 2.5. 1 Inverse roles 37 2.5. 2 Number restrictions 39 2.5. 3 Nominals 41 2.5. 4 Role hierarchies 42 2.5. 5 Transitive roles 42 2.6 DLs and other logics 44 2.6. 1 DLs as decidable fragments of first-order logic 44 2.6. 2 DLs as cousins of modal logic 46 2.7 Historical context and literature review 48
A Novel Regression Model Combining Instance Based Rule Mining With EM Algorithm

In recent years, there have been increasing efforts to apply association rule mining to build Associative Classification (AC) models. However, the similar area that applies association rule mining to build Associative Regression (AR) models has not been well explored. In this work, we fill this gap by presenting a novel regression model based on association rules called AREM. AREM derives a set of regression rules by: (i) applying an instance based approach to mine itemsets which form the regression rules’ left hand side, and (ii) developing a probabilistic model which determines, for each mined itemset, the corresponding rule’s right hand side and the importance weight. To address the computational bottleneck of the traditional two-step approach for itemset mining, AREM utilizes an Instance-Based Itemset Miner (IBIMiner) algorithm that directly discovers the final set of itemsets. IBIMiner incorporates various methods to bound the quality of any future extensions of the itemset under consideration. These bounds are then used to prune the search space. In addition, AREM treats the regression rules’ right hand side and importance weights as parameters of a probabilistic model, which are then learned in the expectation and maximization (EM) framework. The extensive experimental evaluation shows that our bounding strategies allow IBIMiner to considerably reduce the runtime and the EM optimization can improve the predictive performance dramatically. We also show that our model can perform better than some of the state of the art regression models.
Stochastic Scheduling of Renewable and CHP-Based Microgrids

Microgrids (MGs) are considered as a key solution for integrating renewable and distributed energy resources, combined heat and power (CHP) systems, as well as distributed energy-storage systems. This paper presents a stochastic programming framework for conducting optimal 24-h scheduling of CHP-based MGs consisting of wind turbine, fuel cell, boiler, a typical power-only unit, and energy storage devices. The objective of scheduling is to find the optimal set points of energy resources for profit maximization considering demand response programs and uncertainties. The impact of the wind speed, market, and MG load uncertainties on the MG scheduling problem is characterized through a stochastic programming formulation. This paper studies three cases to confirm the performance of the proposed model. The effect of CHP-based MG scheduling in the islanded and grid-connected modes, as well as the effectiveness of applying the proposed DR program is investigated in the case studies.
Inhibition of Return Is Modulated by Negative Stimuli: Evidence from Subliminal Perception

Inhibition of return (IOR) is considered as a “blindness mechanism” that emotional stimuli have no impact on it. Most previous studies suggested that IOR was not modulated by emotional cues. However, one key question they ignored was that only supraliminal presentation of emotional stimuli was used in their experiments. The present experiment is aimed at exploring the possible interaction between the IOR effect and subliminal emotional process. We manipulated three different kinds of valence strength of negative stimuli (high negative, HN; moderate negative, MN; low negative, LN) which were presented under the subliminal perception level and an event-related potentials (ERPs) recording was adopted. The results showed that, compared to MN and HN, the IOR effect triggered by peripheral cues was more significant for LN with aspects of behavioral and electrophysiological data (a reduction P1 effect, more negative on cued trials than on uncued trials for both early posterior Nd and Nd components). This indicated that IOR can be modulated by emotionally relevant stimuli. The automatic processing that was triggered by subliminally negative stimuli of peripheral cues had an influence on the shifting of spatial attention that was triggered by IOR. These two mechanisms may occur in the perceptual stage simultaneously.
How effects on health equity are assessed in systematic reviews of interventions.

BACKGROUND Enhancing health equity has now achieved international political importance with endorsement from the World Health Assembly in 2009. The failure of systematic reviews to consider effects on health equity is cited by decision-makers as a limitation to their ability to inform policy and program decisions. OBJECTIVES To systematically review methods to assess effects on health equity in systematic reviews of effectiveness. SEARCH STRATEGY We searched the following databases up to July 2 2010: MEDLINE, PsychINFO, the Cochrane Methodology Register, CINAHL, Education Resources Information Center, Education Abstracts, Criminal Justice Abstracts, Index to Legal Periodicals, PAIS International, Social Services Abstracts, Sociological Abstracts, Digital Dissertations and the Health Technology Assessment Database. We searched SCOPUS to identify articles that cited any of the included studies on October 7 2010. SELECTION CRITERIA We included empirical studies of cohorts of systematic reviews that assessed methods for measuring effects on health inequalities. DATA COLLECTION AND ANALYSIS Data were extracted using a pre-tested form by two independent reviewers. Risk of bias was appraised for included studies according to the potential for bias in selection and detection of systematic reviews. MAIN RESULTS Thirty-four methodological studies were included. The methods used by these included studies were: 1) Targeted approaches (n=22); 2) gap approaches (n=12) and gradient approach (n=1). Gender or sex was assessed in eight out of 34 studies, socioeconomic status in ten studies, race/ethnicity in seven studies, age in seven studies, low and middle income countries in 14 studies, and two studies assessed multiple factors across health inequity may exist.Only three studies provided a definition of health equity. Four methodological approaches to assessing effects on health equity were identified: 1) descriptive assessment of reporting and analysis in systematic reviews (all 34 studies used a type of descriptive method); 2) descriptive assessment of reporting and analysis in original trials (12/34 studies); 3) analytic approaches (10/34 studies); and 4) applicability assessment (11/34 studies). Both analytic and applicability approaches were not reported transparently nor in sufficient detail to judge their credibility. AUTHORS' CONCLUSIONS There is a need for improvement in conceptual clarity about the definition of health equity, describing sufficient detail about analytic approaches (including subgroup analyses) and transparent reporting of judgments required for applicability assessments in order to assess and report effects on health equity in systematic reviews.