Miracle-dz/UniFAR-FTUs huggingface dataset:
Therapeutic impact of Aloe Vera Gel on Ethanol Induced Gastric Ulcer in Rat Through Modulation of MYD88 Gene Expression

Gastric ulcers are among the major GIT problems impacting people globally. A number of natural compounds have been evaluated for gastric ulcer treatment. One of the most popularly used medicinal plants is Aloe vera, which has powerful anti-inflammatory and healing actions. Pantoprazole was used as a reference drug. The current investigation is intended to determine the therapeutic benefits of Aloe Vera in gastric ulcers triggered by ethanol in rats and to clarify if Aloe Vera achieves its therapeutic benefits by improving mucosal immunity through modulating MyD88 expression. Rats were divided into four groups: normal control, ethanol, ethanol + Aloe Vera, and ethanol + Pantoprazole. Gastric ulceration was triggered by giving only a single dose of 100% ethanol (5 ml/kg b.w.t.) orally. Aloe Vera and Pantoprazole were given orally for 2 weeks. At the end of the experiment, after rat sacrificing and stomach harvesting, macroscopic, molecular, and histopathological evaluations were done. The results revealed that the stomach mucosa in the ethanol group developed a severe ulcerative lesion. Also, myeloid differentiation primary response protein 88 (MYD88) gene expression was significantly upregulated. The ethanol group's histopathological examination revealed severe epithelial damage, inflammation, and edema. The macroscopic mucosal lesion, molecular alterations, and histopathological abnormalities are all alleviated by Aloe Vera treatment. Aloe Vera is more significant than medical treatment with pantoprazole. Finally, we concluded that Aloe Vera's ability to mitigate stomach ulcers is through its anti-inflammatory and healing capacities. Thus, Aloe Vera could potentially be utilized as a medication for relieving gastric ulcers.
Controls on the 87Sr/86Sr composition of seawater from the Middle Eocene to Oligocene: Hole 689B, Maud Rise, Antarctica

A 87Sr/86Sr isotope curve of the middle Eocene to Oligocene was produced from analysis of foraminifera in Ocean Drilling Program Hole 689B, Maud Rise, near the coast of Antarctica. Sediments from the hole are well preserved with no evidence of diagenetic alteration. The sequence is nearly complete from 46.3 to 24.8 Ma, with an average sampling interval of 166 kyr. Excellent magnetostratigraphy in Hole 689B allows calibration to the geomagnetic polarity time scale of Cande and Kent (1992). Marine strontium isotopic ratios were nearly stable from 46.3 to 35.5 Ma, averaging near 0.70773, after which they began to increase. A slow increase began after 40.4 Ma, rising at a rate of only about 8×10−6/m.y. from base values of 0.707707. From 35.5 Ma to 24.8 Ma the average slope increased to 40×10−6/m.y. The slope remained constant at least until 24.8 Ma, when the record becomes discontinuous owing to unconformities. We evaluate several possible controls on the marine strontium isotope curve that could have led to the observed growth in 87Sr/86Sr ratios near the Eocene/Oligocene boundary. Three mechanisms are considered, including the onset of Antarctic glaciation, increased mountain building in the Himalayan-Tibetan region, and decreased hydrothermal activity. None of the mechanisms alone seems to adequately explain the increased 87Sr/86Sr ratios during the Oligocene. Glaciation as a weathering agent was too episodic and probably began too late to explain the upturn in marine 87Sr/86Sr ratios. There is evidence that uplift in the Himalayan-Tibetan region began in the Miocene, much too late to control Oligocene strontium isotope ratios. Lastly, hydrothermal flux changes since the Eocene were apparently not great enough alone to account for the rise in marine 87Sr/86Sr ratios. We suggest that a combination of causes, such as decreased hydrothermal activity perhaps followed by increased glaciation and mountain building, might best explain the growth of the marine 87Sr/86Sr curve during the Oligocene.
Airborne Visible/Infrared Imaging Spectrometer (Aviris) Spectrometer Design And Performance

The development of the Airborne Visible/Infrared Imaging Spectrometer (AVIRIS) has been completed at the Jet Propulsion Laboratory, California Institute of Technology. This paper outlines the functional requirements for the spectrometer optics subsystem, and describes the spectrometer optical design. The optical subsystem performance is shown in terms of spectral modulation transfer functions, radial energy distributions and system transmission at selected wavelengths for the four spectrometers. An outline of the spectrometer alignment is included.
HairStep : Transfer Synthetic to Real Using Strand and Depth Maps for Single-View 3D Hair Modeling – Supplementary Materials

Statistics of data distribution. To construct HiSa and HiDa, we collect 1,250 clear portrait images with various hairstyles from the Internet, where 80% are female and 20% are male. We classify the collected hairstyles into three classes, i.e., Short, Middle and Long, according to the position of their hair ends. If hair ends are above the mouth, the hairstyle will be classified as Short. If hair ends are below the shoulder, the hairstyle belongs to Long class. Otherwise, it is Middle. We collect 300 Short hair, 300 Middle hair and 650 Long hair. As for the curl type, the number of straight, wavy and curly are 210, 620, 420, respectively. More examples about strand map annotation and depth pair sampling are shown in Fig. S1.
Characterization of Obesity-associated Long Noncoding RNAs in Lung

Obesity often increases the risk of cancer and worsens the prognosis. Unlike most types of cancer, several studies concluded that obesity had an inverse inﬂuence on LUAD survival. Increasing evidence showed that obesity-related and adipocyte-derived lncRNAs were associated with cancer initiation, progression, drug resistance, and the tumor microenvironment in lung cancer. In the present study, we identiﬁed two BMI-associated lncRNAs (LINC01500 and lnc-MAFB-1) that could potentially regulate tumor progression in LUAD. Both lncRNAs downregulated signiﬁcantly in the obese lung. The increased expression level of LINC01500 could be observed in LUAD tumors and predict poorer survival. In addition, through estimation from bulk RNA-seq and proﬁling in single-cell sequencing, we found that the expressions of both BMI-associated lncRNAs were associated with macrophages. The downregulation of BMI-associated lncRNAs could create a less immunosuppressive microenvironment, leading to a more eﬃcient response toward immunotherapy. To our knowledge, this is the ﬁrst study to investigate BMI-associated lncRNAs in lung. We believe our ﬁndings can expand the understanding of obesity and the immune microenvironment in lung cancer.
Stress Analysis on Walls in Complex Fluids with Fluid-Solid Interaction

STRESS ANALYSIS ON WALLS IN COMPLEX FLUIDS WITH FLUIDSOLID INTERACTION Dehong Fang, M.S. Department of Mechanical Engineering Northern Illinois University, 2022 Dr. Jifu Tan, Director The wall shear stress (WSS) in blood vessels influences many b iological processes, such as atherosclerosis, clot growth, angiogenesis, aneurysm rupture, and blood cell transport and adhesion. The deformable red blood cells (RBCs) in blood flow make t he WSS even more complex. To analyze the WSS in complex fluids with cell suspensions, numerical simulations of blood flows i n s imple s traight c hannels w ere c onducted, w here t he fluid-solid interactions were simulated by immersed boundary-lattice Boltzmann method. The spatiotemporal dynamics of WSS were analyzed using dynamic mode decomposition (DMD), which is a technique that can extract the low-rank spatiotemporal features from complex fluids. The velocity fields and traction forces on the wall were an alyzed. The dynamic modes showed the fluctuations a nd d istribution o f t he t raction f orces e xerted by t he c ells o n the vessel wall, where magnitudes of traction forces were sharply increased when RBCs were close to the wall. The dynamic distribution reflected the shapes and l ocations o f the RBC contacting surfaces. The reconstruction of dynamic modes captured features of distribution of traction forces accurately, with an average root-mean-square error (RMSE) of 0.0095 and an average relative RMSE of 3.012%, and average mean absolute error (MAE) is 0.0040 and average relative MAE is 8.806%. The WSS was influenced by tube diameter, RBC deformation, and hematocrit. E.g., radially squeezed RBCs can block the flow and cause a local discrepancy of flow velocity for vessels with small diameters (5 and 8 μm with hematocrits 22.93% and 28.95%, respectively), which are less than the diameter of an RBC (8 μm). Dense distributions of footprints were found on the walls of vessels with large diameters (8, 10, and 15 μm with a hematocrit around 30%), where more RBCs were moving and colliding with each other, and their maximum traction forces were around 0.3 Pa. Local peaks of fluctuated traction forces caused by wall contacting of RBCs were around 0.15 Pa for cases of large diameters (8, 10, and 15 μm), and the traction forces increased as RBCs approached to the wall and then decreased as RBCs moved away. The dynamics of the footprint of traction forces were captured by DMD models, and the majority of trends of fluctuations of traction forces are matched. The current research can be potentially used to construct reduced order models for complex flows. NORTHERN ILLINOIS UNIVERSITY DE KALB, ILLINOIS AUGUST 2022 STRESS ANALYSIS ON WALLS IN COMPLEX FLUIDS WITH FLUID-SOLID INTERACTION BY DEHONG FANG © 2022 Dehong Fang A THESIS SUBMITTED TO THE GRADUATE SCHOOL IN PARTIAL FULFILLMENT OF THE REQUIREMENTS FOR THE DEGREE MASTER OF SCIENCE DEPARTMENT OF MECHANICAL ENGINEERING Thesis Director: Dr. Jifu Tan
Time-Series Momentum in a Small European Stock Market: Evidence from a New Historical Financial Dataset

In this paper, we examine the Portuguese stock market for indication of time-series momentum effects using a new historical financial dataset that covers about 120 years of data. We find strong time-series momentum effects that cannot be explained by conventional risk factors. The positive return continuation seems to last for a period of 12 months, being heavily concentrated at the first month. At longer investment horizons, returns tend to mean-revert. The market exhibited significant time-series momentum for all look-back and holding periods of 12 months or less. A strategy with a 1-month look-back period and a 12-month holding period is shown to be the most profitable yielding a Sharpe ratio roughly 5.4 times that generated by a passive strategy. Time-series momentum strategies tend to perform best during extreme up-market periods and deliver the worst returns during down markets. This suggests that the strategy may not offer significant diversification benefits. Our findings add to the evidence that time-series momentum effects are not a product of data mining and are difficult to reconcile with the assertion that stock markets follow a random walk.
Mound ZZl, Nixtun-Ch'ich', Petén, Guatemala: Rescue Operations at a Long-Lived Structure in the Maya Lowlands

Abstract Mound ZZl, located on the tip of the peninsular portion of the large lowland Maya site of Nixtun-Ch’ich’ in Petén, Guatemala, was investigated in 2007 during a salvage operation. An axial trench revealed a long sequence of activity in the area, beginning before 1000 B. C. and extending into the early 18th century. Early platform construction was accompanied by feasting and smashing of Middle Preclassic (1000—400 B.C.) pottery in a termination and/or dedication rite. The mound grew through the construction and reconstruction of numerous platforms and structures—and further episodes of termination and dedication—that primarily extended it laterally, rather than vertically. The location of Mound ZZl and its features—reincorporation of Middle Preclassic fill materials; secondary burials; clay figurines; protection by a large wall-ditch complex; pecked plaster symbols; and the presence of a Spanish mission church—suggest that it was a key civic-ceremonial component of the region's sacred landscape for nearly three thousand years.
El uso del método Delphi en la definición de los criterios para una formación de calidad en Animación sociocultural y tiempo libre

To offer a quality formation to the sociocultural agents (sociocultural entertainers, monitors of free time, educators of average open.) he demands an exhaustive analysis of the formative task made by the agencies that take care of this formation and requires negotiated criteria that orient this formation. In this work the methodology process followed is described to define of negotiated way criteria of the quality of the formation regulated and non formal in Sociocultural Animation, Leisure and Free Time from the judgment contributed by a group of experts. The Delphi Method has been the methodology frame from which the search of negotiated and decided group opinions is had boarded on which these criteria haven been defined.
A Last Glacial Maximum World-Ocean simulation at eddy-permitting resolution – Part 2: Confronting the paleo-proxy data

The thermohaline circulation (THC) corresponds to the large time- and spatial-scales ocean circulation associated with the transport of heat and salt, and is known to be an important factor controlling the climate variability. The large scales involved in the THC make it difficult to observe, and therefore the synergy of numerical models and climate proxy reconstructions is particularly relevant to study the characteristics of this circulation in the present and past climates.In this doctoral thesis, the THC during the Last Glacial Maximum (LGM) and the Present-Day (PD) is explored using a state-of-the-art Ocean General Circulation Model in its high- and low-resolution regimes. By comparing the LGM model outputs with the paleo-proxy reconstructions, it is shown that the high-resolution simulation improves the representation of the sea surface tem- peratures in the regions where the current structures appear to be complex, i.e., the western boundary currents (Agulhas, Kuroshio, Gulf Stream) and the Antarctic Circumpolar Current, although statistical comparisons with paleo- proxy reconstructions are not significantly improved on a global scale.The THC involves a superposition of processes acting at widely different spatial and temporal scales, from the geostrophic large-scale and slowly-varying flow to the mesoscale turbulent eddies and at even smaller-scale, the mixing generated by the internal wave field. Not all these processes can be properly resolved in numerical models, and thus need to be parameterized. Analyzing the THC in an eddy-permitting numerical model, it was found that the temporal scales required for diagnosing the Southern Ocean circulation should not exceed 1 month and the spatial scales needed to be taken into account must be smaller than 1°. Important changes in the nature and intensity of the THC were observed between the LGM and PD simulations. An estimation of the turnover times (i.e., the time it takes for the water parcel to make and entire loop on the Conveyor Belt) revealed that the LGM THC could be more vigorous than under the PD conditions. As a result, the ocean transports of heat and freshwater, the oceanic uptake of CO2, the ventilation of the deep ocean and the reorganization of the passive and active tracers (e.g., temperature, salinity, greenhouse gases, nutrients) can be altered in these different regimes.
How systematic is organized tropical convection within the MJO?

Recent theories of the dynamics of the Madden‐Julian Oscillation (MJO) have been building on its multiscale structure. While it is observed that much of the convection within the MJO envelope is related to higher frequency equatorial waves, it is not known to what extent this organization is systematic from one MJO event to another. For instance, it is of interest to know whether MJO favors waves of particular types and propagation direction, and how this variability changes seasonally. This work presents a wavenumber‐frequency spectral analysis of the MJO convective envelope, which indicates that there is no strong preferred scale of high frequency organization that is ubiquitous to the MJO. This null finding supports the use of convective parametrizations in modeling the MJO since, while moist convection is likely critical to its initiation and maintenance, the particular details of that organization may not be critical for its prediction and simulation.
Supplementary Material for PartManip: Learning Cross-Category Generalizable Part Manipulation Policy from Point Cloud Observations

We select 494 object instances from GAPartNet [11] dataset. GApartNet provides large-scale articulated objects with rich annotations. For doors and drawers, our benchmark requires a handle on it. For the button, there is no constraint. Because there are too many buttons on some remote or phone, we randomly select a maximum of 5 buttons on each object. The total benchmark contains 494 objects and 1432 different target parts.
On the use of the discrete power function for-building public-key cryptosystems

This paper proposes a generalization of the discrete power function that can be used for constructing public-key cryptosystems. Particular cases of this function, with specific values for the encryption exponent, are used in RSA and Rabin cryptosystem. This paper provides a cryptosystem that can be built on a generalization of this function that holds for any value of the encryption exponent.
Reconstruction of the exhumation path of the Alpe Arami garnet‐peridotite body from depths exceeding 160 km

ABSTRACT Chemical disequilibrium exists between all phases of the Alpe Arami garnet‐peridotite body (Ticino, Switzerland) which hampers the evaluation of P‐T conditions of origin, yet disequilibrium offers the inherent possibility to derive a P‐T‐t path for this mantle slice. We tried to tackle this problem by carrying out new mineral analyses and taking diffusion rates and bulk‐rock compositional effects into consideration. Peak metamorphic conditions from mineral core compositions were estimated as 112050C/50.2 GPa. These values are significantly higher than previously published results and were determined from a combination of the O'Neill & Wood (1979) Fe/Mg garnet‐olivine exchange thermometer and the Al‐in‐orthopyroxene barometer (Brey & Köhler, 1990), and are supported by the Ca/Cr ratios in garnet, which are in accord with these conditions. Details of the exhumation path were derived from (1) rim compositions of minerals that yield a first retrograde stage of 720 50C/2 0.25 GPa (2) a spinel lherzolite assemblage in narrow shear zones (tectonic phase F0″, after Möckel, 1969) which documents a second retrograde stage at 500–600C/0.8‐l.5 GPa. The Ca content in olivine (Köhler & Brey, 1989) can be used to evaluate further P‐T conditions along the retrograde path. We measured very low values (30–40 ppm Ca) in the cores of olivine and a remarkable increase towards the rim (120 ppm). The low core values may reflect an equilibrium stage during the main Alpine metamorphism. The increasing values towards the olivine rims probably represent a late‐stage heating event. The initial cooling rates for the peridotite body are between 2700 and 5100C Ma‐1, depending on which diffusion data are used.
Crime is Terribly Revealing: Information Technology and Police Productivity*

An increasing number of police departments use information technology (IT) to optimize patrolling strategies, yet little is known about its e ectiveness in preventing crime. Based on quasi-random access to predictive policing, this study shows that IT improves police productivity as measured by crime clearance rates. Thanks to detailed information on individual incidents and o ender-level identi ers it also shows that criminals strategies are predictable. Moreover, the introduction of predictive policing coincides with a large negative trend-discontinuity in crime rates. The bene t-cost ratio of this IT innovation appears to be large.
Synthetic Observations of the Planetary Boundary Layer from Space: A Retrieval Observing System Simulation Experiment Framework

To address critical gaps identified by the National Academies of Sciences, Engineering and Medicine in the current Earth system observation strategy, the 2017-2027 Decadal Survey for Earth Science and Applications from Space recommended incubating concepts for future targeted observables including the atmospheric planetary boundary layer (PBL). A subsequent NASA PBL Incubation Study Team Report identified measurement requirements and activities for advancing the maturity of the technologies applicable to the PBL targeted observables and their associated science and applications priorities. While the PBL is the critical layer where humans live and surface energy, moisture, and mass exchanges drive the Earth system, it is also the farthest and most inaccessible layer for spaceborne instruments. Here we document a PBL retrieval Observing System Simulation Experiment (OSSE) framework suitable for assessing existing and new measurement techniques and determining their accuracy and improvements needed for addressing the elevated Decadal Survey requirements. In particular, the benefits of Large-Eddy Simulation (LES) are emphasized as a key source of high-resolution synthetic observations for key PBL regimes: from the tropics, through sub-tropics and mid-latitudes, to subpolar and polar regions. The potential of LES-based PBL retrieval OSSEs is explored using six instrument simulators: global navigation satellite system-radio occultation, differential absorption radar, visible to shortwave infrared spectrometer, infrared sounder, multi-angle imaging radio spectrometer, and microwave sounder. The crucial role of LES in PBL retrieval OSSEs and some perspectives for instrument developments are discussed.
Participant satisfaction with Youth Justice Conferencing

Aims: To evaluate offender and victim satisfaction with New South Wales (NSW) Youth Justice Conferences (YJCs) immediately after conference participation and to re-assess victim satisfaction 4 months after the conference date. Method: A self-report survey designed to assess satisfaction with YJCs was completed by 263 offenders and 141 victims immediately following their participation in a NSW YJC. Additionally, 96 victims also participated in a phone-based survey 4 months after the conference. Results: When asked immediately following the conference, more than 85 per cent of offenders and victims reported being 'satisfied' or 'very satisfied' with most aspects of the conference. High levels of satisfaction with conferencing were also reported by victims 4 months after the conference. For some measures, however, the percentage of victims who were 'satisfied' or 'very satisfied' was not as high at the 4-month follow-up, as it was in the baseline survey. The aspect of conferencing that victims at the 4-month follow-up reported the least satisfaction with was the lack of feedback they received from conference staff about the offender's completion of the outcome plan. Fewer than half of the victims were 'satisfied' or 'very satisfied' with this part of the conference. Conclusion: The results of this study suggest that offender and victim satisfaction is high immediately following a YJC. Even 4 months after a YJC, victim satisfaction with most aspects of conferencing remains high. Satisfaction levels may be increased still further if, at some point prior to the end of the statutory time-period for completing the plan, victims were provided with feedback about the offender's progress towards completing the outcome plan. Further research also needs to be conducted comparing victim satisfaction following a conference with victim satisfaction following a court appearance.