Miracle-dz/UniFAR-FTUs huggingface dataset:
Review of the Magnitude of Folate and Vitamin B12 Deficiencies Worldwide

Human deficiencies of folate and vitamin B12 result in adverse effects which may be of public health significance, but the magnitude of these deficiencies is unknown. Therefore, we examine the prevalence data currently available, assess global coverage of surveys, determine the frequency with which vitamin status assessment methods are used, and identify patterns of status related to geographical distribution and human development. Surveys were identified through PubMed and the Vitamin and Mineral Nutrition Information System at the World Health Organization (WHO). Since different thresholds were frequently used to define deficiency, measures of central tendency were used to compare blood vitamin concentrations among countries. The percentage of countries with at least one survey is highest in the WHO Regions of South-East Asia and Europe. Folate and vitamin B12 status were most frequently assessed in women of reproductive age (34 countries), and in all adults (27 countries), respectively. Folate status assessment surveys assessed plasma or serum concentrations (55%), erythrocyte folate concentrations (21%), or both (23%). Homocysteine was assessed in one-third of the surveys of folate and vitamin B12 status (31% and 34% respectively), while methylmalonic acid was assessed in fewer surveys of vitamin B12 status (13%). No relationship between vitamin concentrations and geographical distribution, level of development, or population groups could be identified, but nationally representative data were few. More representative data and more consistent use of thresholds to define deficiency are needed in order to assess whether folate and vitamin B12 deficiencies are a public health problem.
Trace: Tennessee Research and Creative Exchange Frequency-dependent Selection by Wild Birds Promotes Polymorphism in Model Salamanders Recommended Citation Frequency-dependent Selection by Wild Birds Promotes Polymorphism in Model Salamanders

Background: Co-occurrence of distinct colour forms is a classic paradox in evolutionary ecology because both selection and drift tend to remove variation from populations. Apostatic selection, the primary hypothesis for maintenance of colour polymorphism in cryptic animals, proposes that visual predators focus on common forms of prey, resulting in higher survival of rare forms. Empirical tests of this frequency-dependent foraging hypothesis are rare, and the link between predator behaviour and maintenance of variation in prey has been difficult to confirm. Here, we show that predatory birds can act as agents of frequency-dependent selection on terrestrial salamanders. Polymorphism for presence/absence of a dorsal stripe is widespread in many salamander species and its maintenance is a long-standing mystery.
On the Metrics for Benchmarking Vulnerability Detection Tools

Research and practice show that the effectiveness of vulnerability detection tools depends on the concrete use scenario. Benchmarking can be used for selecting the most appropriate tool, helping assessing and comparing alternative solutions, but its effectiveness largely depends on the adequacy of the metrics. This paper studies the problem of selecting the metrics to be used in a benchmark for software vulnerability detection tools. First, a large set of metrics is gathered and analyzed according to the characteristics of a good metric for the vulnerability detection domain. Afterwards, the metrics are analyzed in the context of specific vulnerability detection scenarios to understand their effectiveness and to select the most adequate one for each scenario. Finally, an MCDA algorithm together with experts' judgment is applied to validate the conclusions. Results show that although some of the metrics traditionally used like precision and recall are adequate in some scenarios, others require alternative metrics that are seldom used in the benchmarking area.
A look at unsociability on Facebook

We propose unsociability as a novel perspective to approach and support online social interactions. With examples taken from focus group discussions, we highlight the need of users to save face in their online interactions within social network sites. We claim that people follow a "social-over-technical" pattern on Facebook, as they base their interactions on their social understanding of this site instead of on its technical capabilities. These social norms and patterns challenge social translucence which has for more than a decade been recognized as one of the cornerstones of social computing systems.
A Trust Model for the Reliability of Agent Communications

Communication is the cornerstone of decentralized systems. However, in open and decentralized multi-agent systems, assumptions on the internal implementation of the agents are reduced to the minimum, in order to allow heterogeneous agents to enter or quit the system at any time. Therefore, some agents that do not respect – voluntarily or not – the rules for a “good” communicative behavior may be introduced in the system. In this paper, we propose a trust model for the reliability of agent communications. We define inconsistencies in the communications (represented as social commitments) in order to enable agents to detect lies and update their trust model of other agents. Then, agents use their trust model to decide whether to trust or not a new commitment. Some results are presented based on experimentations on the functions proposed to compute the reputation values that compose the trust model.
A Blind Watermarking Scheme Using New Nontensor Product Wavelet Filter Banks

As an effective method for copyright protection of digital products against illegal usage, watermarking in wavelet domain has recently received considerable attention due to the desirable multiresolution property of wavelet transform. In general, images can be represented with different resolutions by the wavelet decomposition, analogous to the human visual system (HVS). Usually, human eyes are insensitive to image singularities revealed by different high frequency subbands of wavelet decomposed images. Hence, adding watermarks into these singularities will improve the imperceptibility that is a desired property of a watermarking scheme. That is, the capability for revealing singularities of images plays a key role in designing wavelet-based watermarking algorithms. Unfortunately, the existing wavelets have a limited ability in revealing singularities in different directions. This motivates us to construct new wavelet filter banks that can reveal singularities in all directions. In this paper, we utilize special symmetric matrices to construct the new nontensor product wavelet filter banks, which can capture the singularities in all directions. Empirical studies will show their advantages of revealing singularities in comparison with the existing wavelets. Based upon these new wavelet filter banks, we, therefore, propose a modified significant difference watermarking algorithm. Experimental results show its promising results.
Association Between Acute Statin Therapy, Survival, and Improved Functional Outcome After Ischemic Stroke: The North Dublin Population Stroke Study

Background and Purpose— Statins improve infarct volume and neurological outcome in animal stroke models. We investigated the relationship between statin therapy and ischemic stroke outcome in the North Dublin Population Stroke Study. Methods— A population-based prospective cohort study was performed using rigorous ascertainment methods. Prestroke and acute (≤72 hours) poststroke medications were recorded. Modified Rankin score and fatality were assessed at 7, 28, and 90 days and 1 year. Results— Of 448 ischemic stroke patients, statins were prescribed before stroke onset in 30.1% (134/445) and were begun acutely (≤72 hours) in an additional 42.5% (189/445). On logistic regression analysis, adjusting for age, prestroke disability (modified Rankin scale), NIHSS score, hypertension, and aspirin, new poststroke statin therapy was independently associated with improved early and late survival (compared with statin untreated patients: OR for death, 0.12; CI, 0.03–0.54 at 7 days; OR, 0.19; CI, 0.07–0.48 at 90 days; OR, 0.26; CI, 0.12–0.55 at 1 year; P≤0.006 for all). Similar findings were observed for statin therapy before stroke onset (adjusted OR for death compared with statin-untreated-patients, 0.04; CI, 0.00–0.33; P=0.003 at 7 days; OR, 0.23; CI, 0.09–0.58; P=0.002 at 90 days; OR, 0.48; CI, 0.23–1.01; P=0.05 at 1 year). Conclusions— Statin therapy at stroke onset and newly begun statins were associated with improved early and late outcomes, supporting data from experimental studies. Randomized trials of statin therapy for treatment of acute stroke are needed.
A new Dendropsophus Fitzinger, 1843 (Anura: Hylidae) of the parviceps group from the lowlands of the Guiana Shield.

Many Amazonian frog species that are considered widely distributed may actually represent polyspecific complexes. A minute tree frog from the Guiana Shield originally assigned to the allegedly widely distributed Dendropsophus brevifrons proved to be a yet undescribed species within the D. parviceps group. We herein describe this new species and present a phylogeny for the D. parviceps group. The new species is diagnosed from other Dendropsophus of the parviceps group by its small body size (19.6-21.7 mm in males, 22.1-24.5 mm in females), thighs dorsally dark grey with cream blotches without bright yellow patch, absence of dorsolateral and canthal stripe, and an advertisement call comprising trills (length 0.30-0.35 s) composed of notes emitted at a rate of 131-144 notes/s, generally followed by click series of 2-3 notes. Its tadpole is also singular by having fused lateral marginal papillae and absence of both labial teeth and submarginal papillae. Genetic distances (p-distance) are >5.3% on the 12S and >9.3% on the 16S from D. brevifrons, its closest relative. This species occurs from the Brazilian state of Amapá, across French Guiana and Suriname to central Guyana and is likely to also occur in adjacent Brazilian states and eastern Venezuela. This species is not rare but is difficult to collect because of its arboreal habits and seasonal activity peaks.
Méthodes et modèles pour la visualisation de grandes masses de données multidimensionnelles nominatives dynamiques. (Methods and model for huge amount of nominative multidimendionnal dynamic data visualization)

Since ten years, informations visualization domain knows a real interest.Recently, with the growing of communications, the research on social networks analysis becomes strongly active. In this thesis, we present results on dynamic social networks analysis. That means that we take into account the temporal aspect of data. We were particularly interested in communities extraction within networks and their evolutions through time. [. ]
Packet transfer of DLMS/COSEM standards for smart grid

In this paper, we review packet transfer from DCU to meter by using DLMS/COSEM protocol. We descript the kind of book of DLMS/COSEM and explain the combination of DLMS/COSEM such as COSEM application process, COSEM application layer and connection manager. We show some example of packet transfer from application layer of DLMS/COSEM to data link layer and summary the size of packet of each command and response of DLSM/COSEM. Additionally, we will descript the ZigBee basic knowledge that used to physical layer of DLMS/COSEM protocol.
Smartphone Apps for Schizophrenia: A Systematic Review

Background There is increasing interest in using mobile technologies such as smartphones for improving the care of patients with schizophrenia. However, less is known about the current clinical evidence for the feasibility and effectiveness of smartphone apps in this population. Objective To review the published literature of smartphone apps applied for the care of patients with schizophrenia and other psychotic disorders. Methods An electronic database search of Ovid MEDLINE, the Cochrane Central Register of Controlled Trials, Health Technology Assessment Database, Allied and Complementary Medicine, Health and Psychosocial Instruments, PsycINFO, and Embase was conducted on May 24, 2015. All eligible studies were systematically reviewed, and proportional meta-analyses were applied to pooled data on recruitment, retention, and adherence to examine the overall feasibility of smartphone interventions for schizophrenia. Results Our search produced 226 results from which 7 eligible articles were identified, reporting on 5 studies of smartphone apps for patients with schizophrenia. All examined feasibility, and one assessed the preliminary efficacy of a smartphone intervention for schizophrenia. Study lengths varied between 6 and 130 days. Overall retention was 92% (95% CI 82-98%). Participants consistently used the smartphone apps on more than 85% of days during the study period, averaging 3.95 interactions per person per day. Furthermore, participants responded to 71.9% of automated prompts (95% CI 65.7-77.8%). Participants reported a range of potential benefits from the various interventions, and user experience was largely positive. Conclusions Although small, the current published literature demonstrates strong evidence for the feasibility of using smartphones to enhance the care of people with schizophrenia. High rates of engagement and satisfaction with a broad range of apps suggest the nascent potential of this mobile technology. However, there remains limited data on the efficacy of such interventions.
Tag-based Information Flow Analysis for Document Classification in Provenance

A crucial aspect of certain applications such as the ones pertaining to Intelligence domain or Health-care, is to manage and protect sensitive information effectively and efficiently. In this paper, we propose a tagging mechanism to track the flow of sensitive or valuable information in a provenance graph and automate the process of document classification. When provenance is initially recorded, the documents of a provenance graph are assumed to be annotated with tags representing their sensitivity or priority. We then propagate the tags appropriately on the newly generated documents using additional inference rules defined in this paper. This approach enables users to conveniently query to identify sensitive or valuable information, which can now be efficiently managed or protected once identified.
Preperiodic points and unlikely intersections

In this article, we combine complex-analytic and arithmetic tools to study the preperiodic points of one-dimensional complex dynamical systems. We show that for any fixed a, b ∈ C, and any integer d ≥ 2, the set of c ∈ C for which both a and b are preperiodic for z + c is infinite if and only if a = b. This provides an affirmative answer to a question of Zannier, which itself arose from questions of Masser concerning simultaneous torsion sections on families of elliptic curves. Using similar techniques, we prove that if rational functions φ,ψ ∈ C(z) have infinitely many preperiodic points in common, then all of their preperiodic points coincide (and in particular the maps must have the same Julia set). This generalizes a theorem of Mimar, who established the same result assuming that φ and ψ are defined over Q. The main arithmetic ingredient in the proofs is an adelic equidistribution theorem for preperiodic points over number fields and function fields, with non-archimedean Berkovich spaces playing an essential role.
Innovative Approaches for Immune Tolerance to Factor VIII in the Treatment of Hemophilia A

Hemophilia A (coagulation factor VIII deficiency) is a debilitating genetic disorder that is primarily treated with intravenous replacement therapy. Despite a variety of factor VIII protein formulations available, the risk of developing anti-dug antibodies (“inhibitors”) remains. Overall, 20–30% of patients with severe disease develop inhibitors. Current clinical immune tolerance induction protocols to eliminate inhibitors are not effective in all patients, and there are no prophylactic protocols to prevent the immune response. New experimental therapies, such as gene and cell therapies, show promising results in pre-clinical studies in animal models of hemophilia. Examples include hepatic gene transfer with viral vectors, genetically engineered regulatory T cells (Treg), in vivo Treg induction using immune modulatory drugs, and maternal antigen transfer. Furthermore, an oral tolerance protocol is being developed based on transgenic lettuce plants, which suppressed inhibitor formation in hemophilic mice and dogs. Hopefully, some of these innovative approaches will reduce the risk of and/or more effectively eliminate inhibitor formation in future treatment of hemophilia A.
The Importance of Hemorrhage in the Relationship Between Gross Morphologic Characteristics and Cerebral Symptoms in 376 Carotid Artery Plaques

In a prospective study 376 carotid artery plaques (275 symptomatic, 101 asymptomatic) were obtained from endarterectomies (184 unilateral and 96 bilateral) in 280 patients. The gross morphologic features of each plaque were noted at surgery and, together with the patient's clinical history, stored in computer memory. These data were analyzed in order to investigate the relationship of gross morphologic plaque characteristics with both the presence of cerebral symptoms and the degree of stenosis associated with the plaque. Ulceration was the most frequently observed of the five major gross plaque morphologic characteristics (46.0% of all plaques), but only intramural hemorrhage (30.6% of all plaques) was significantly more common in all symptomatic compared with all asymptomatic plaques (p < 0.02). Hemorrhage was also the only gross characteristic significantly more common in focal symptomatic plaques when compared with either asymptomatic plaques (p < 0.05) or nonfocal symptomatic plaques (p < 0.01). When all the plaques were divided into three broad degrees of stenosis groups (0–39%, 40–69%, 70–99%) on the basis of angiographic data, only hemorrhage showed a significant correlation in incidence with increased degree of plaque stenosis, both when all plaques were considered (p < 0.001) and when only symptomatic plaques were examined (p < 0.001). The results indicate that intramural hemorrhage is the only carotid plaque gross morphologic characteristic significantly more frequent in symptomatic compared with asymptomatic plaques and the only characteristic significantly correlated with increased plaque size. These findings indicate that factors other than plaque ulceration and intraluminal thrombus play an important role in carotid plaque related cerebral symptoms. The data also raise questions concerning the unequivocal value of anticoagulant therapy in carotid artery disease, especially in highly stenotic lesions.
State Amplification Subject to Masking Constraints

This paper considers a state dependent broadcast channel with one transmitter, Alice, and two receivers, Bob and Eve. The problem is to effectively convey (“amplify”) the channel state sequence to Bob while “masking” it from Eve. The extent to which the state sequence cannot be masked from Eve is referred to as leakage. This can be viewed as a secrecy problem, where we desire that the channel state itself be minimally leaked to Eve while being communicated to Bob. This paper is aimed at characterizing the tradeoff region between amplification and leakage rates for such a system. An achievable coding scheme is presented, wherein the transmitter transmits a partial state information over the channel to facilitate the amplification process. For the case when Bob observes a stronger signal than Eve, the achievable coding scheme is enhanced with secure refinement. Outer bounds on the tradeoff region are also derived, and used in characterizing some special case results. In particular, the optimal amplification-leakage rate difference, called as differential amplification capacity, is characterized for the reversely degraded discrete memoryless channel, the degraded binary, and the degraded Gaussian channels. In addition, for the degraded Gaussian model, the extremal corner points of the tradeoff region are characterized, and the gap between the outer bound and achievable rate-regions is shown to be less than half a bit for a wide set of channel parameters.
Sliding Control of Force Reflecting Teleoperation:Preliminary Studies

In this paper, sliding mode nonlinear control is applied to force reflecting teleoperation. Various forms of the sliding mode control law are derived for force feedback master manipulation with an arbitrary factor for force and position scaling. Experiments were performed on a one axis test system and frequency domain Hybrid 2-port matrices are measured and compared between the sliding mode controller and a classical position error-based feedback controller. Time domain experiments are also performed. The model-based portion of the sliding mode controller was shown to be responsible for most of its performance improvement, but the nonlinear sliding component was essential for steady-state position accuracy and robust stability.
Positive direct immunofluorescence and autoantibody profiles in psoriasis patients

Psoriasis and systemic lupus erythematosus are common, but their coexistence is thought to be infrequent. Each of these diseases has a broad clinical spectrum, so that diagnosis may not be straightforward. This study aimed to investigate the following immunological parameters in psoriasis patients: (i) direct immunofluorescence (DIF); (ii) antinuclear antibody; (iii) anti‐double‐stranded DNA (dsDNA); (iv) anti‐Ro; and (v) anti‐nuclear ribonucleoprotein (nRNP). Of 300 cases, comprising 189 men (62.9%) and 111 women (37.1%), 17 (5.7%; 10 men, seven women) were positive for at least one immunological parameter. Nine of 300 (3%; seven male, two female) biopsy specimens from sun‐exposed psoriatic lesions demonstrated bright continuous bands of granular IF along the dermoepidermal junction with immunoreactant immunoglobulin (Ig)G, IgM, C3 and fibrinogen. The intensity of IF at the dermoepidermal junction was graded 3+ and 2+. Three cases demonstrated IgM, two had IgG, two fibrinogen and six cases showed C3. Three cases demonstrated more than one immunoreactant. One case demonstrated C3 at the vessels. No specimen demonstrated IgA deposition. Three hundred sera were obtained from patients with psoriasis, of which five demonstrated elevated antinuclear antibody (ANA) titer; dilution titer varied from 1:80–640. Three had a homogeneous pattern and two had a speckled pattern. None had a peripheral pattern. Five (1.7%) of 300 demonstrated anti‐Ro, two had negative ANA, and three were positive ANA, two of which were speckled and the other homogenous. Anti‐dsDNA, anti‐Sm and anti‐nRNP were not detected. Ten patients had positive DIF but negative ANA, while five had positive ANA; all had negative DIF results. Thus, the incidence of psoriasis and lupus erythematosus coexistence is low and a baseline immunological screening test for psoriasis might not prove worthwhile.