Miracle-dz/UniFAR-FTUs huggingface dataset:
Differences in preeclampsia rates between African American and Caucasian women: trends from the National Hospital Discharge Survey.

BACKGROUND African Americans are at higher risk for preeclampsia compared with Caucasians, but longitudinal changes are unknown. We hypothesized that preeclampsia rates among African Americans would be higher than that of Caucasians and over time would maintain a consistent divergence. METHODS We analyzed the annual prevalence rates and calculated prevalence odds ratios (POR) with 95% confidence intervals (95% CI) for preeclampsia comparing 4,644 African American (weighted 608,109) with 12,131 Caucasian (weighted 1,844,391) women from the National Hospital Discharge Survey (1979-2006), including all women for whom a delivery was associated with preeclampsia. We estimated the race-specific prevalence of preeclampsia while adjusting for age, geographic region, diabetes, essential hypertension, prior myocardial infarction, heart failure, benign essential hypertension complicating a pregnancy, transient hypertension, and gestational diabetes. RESULTS There was an increasing trend in preeclampsia rates per year from 1979 to 2006 for African Americans [POR 0.76 (95% CI 0.49, 1.03)] and Caucasians [0.29 (95% CI 0.17, 0.41)]. However, there was an initial decrease in prevalence from 1979-1988 among African-Americans [-0.96 (95% CI -1.78, -0.14)] that was not seen in Caucasians [0.12 (95% CI -0.33, 0.57)]. Across all study years, preeclampsia rates remained higher for African Americans compared to Caucasians, from a POR of 0.98 (95% CI 0.96, 1.0) to POR of 1.75 (95% CI 1.73, 1.78). CONCLUSION There was an increase in the prevalence of preeclampsia in African Americans compared to Caucasians in the most recent decade under study. This may be explained by healthcare system changes and disparities in obesity. Action is needed to reduce the trajectory of future cardiovascular disease caused by preeclampsia.
Malt1 protease inactivation efficiently dampens immune responses but causes spontaneous autoimmunity

The protease activity of the paracaspase Malt1 has recently gained interest as a drug target for immunomodulation and the treatment of diffuse large B‐cell lymphomas. To address the consequences of Malt1 protease inactivation on the immune response in vivo, we generated knock‐in mice expressing a catalytically inactive C472A mutant of Malt1 that conserves its scaffold function. Like Malt1‐deficient mice, knock‐in mice had strong defects in the activation of lymphocytes, NK and dendritic cells, and the development of B1 and marginal zone B cells and were completely protected against the induction of autoimmune encephalomyelitis. Malt1 inactivation also protected the mice from experimental induction of colitis. However, Malt1 knock‐in mice but not Malt1‐deficient mice spontaneously developed signs of autoimmune gastritis that correlated with an absence of Treg cells, an accumulation of T cells with an activated phenotype and high serum levels of IgE and IgG1. Thus, removal of the enzymatic activity of Malt1 efficiently dampens the immune response, but favors autoimmunity through impaired Treg development, which could be relevant for therapeutic Malt1‐targeting strategies.
QBISM: A Prototype 3-D Medical Image Database System.

in a very investigative, interactive, and iterative fashion. A study is a a of collected a single on a single patient, such a slice MRI study three x-rays of a fractured elbow. Querying and visualizing collections of Machines Inc. Query By Interactive, Spatial Magnetic Resonance Imaging. MRI images show soft-tissue structural information.
Simulation of the Health Monitoring and Disease Warning System on the Pig Herd with a Cloud-based GAMA Platform

More and more Internet of Things devices are being used in precision farming to measure parameters related to animal growth. Sensors from precision feeding systems are used to collect and analyze data on feed intake of group-housed pigs helping farmers to make valuable decisions that help in pig growth. Besides, African Swine Fever (ASF) is a disease occurring in pigs that kills millions of them. The outbreak comes from the lack of management by localities, connection between farms, and the ability to improve productivity. It is a fact that effects of disease on animals can be observed early through data of voluntary feed intake which can be used to detect dangerous outbreaks of ASF over a wide graphical area in real time. This will contribute to reducing economic losses due to epidemics and improving the quality of animal products. In this paper, we first introduce a cloud-based simulation of the precision feeding system to quantify the cumulative feed intake of growing pigs, thanks to which it is possible to detect early signs of disease in the daily decrease in food intake. Secondly, output statistical data on the disease of pig herds from the first simulation are used for the second simulation of ASF transmission in Hanoi, which is an essential tool for policymakers to inform decision-making people and help them understand better the impact of the disease outbreaks. Through these simulations on GAMA platform, we wish to introduce a cost-effective research model on disease transmission in pig herds using cloud-based simulation and illustration instead of investing heavily in expensive actual equipment.
Efeitos do envelhecimento na função coclear

Introduction: As long as the individual grows old, all his organs suffer multiple organic transformations, and the deterioration of the sensorial auditory function appears as one of the most frustrating sensorial deficits. The aim of this work was to evaluate aging effects on the cochlear function. Material and Method: a group consisting of fifty persons with ages from 61 to 90 years, with high frequency hearing loss, eight men and 42 women, was evaluated. The patients underwent basic audiologic evaluation, transient and distortion product emissions. Results: Age interfered in the pure tone thresholds and women presented best thresholds. In the transient and distortion product otoacoustic emissions, aging interfered in the results and women were the only ones presenting responses in the transient otoacoustic emissions. Conclusion: Age influenced negatively over the auditory function on both genders, and the impact of the deterioration was more prevalent on men.
Digital back-end for RFI detection and mitigation in microwave radiometers

Radio-frequency interference (RFI) is a serious problem in microwave radiometry. In order to process the received data in real time, a powerful back-end for RFI detection and mitigation system must be implemented. This system includes many techniques against RFI, like time, frequency domain and spectrogram analysis. A wavelet-based RFI-mitigation technique is implemented in hardware. The interfering signal is estimated by using the powerful denoising capabilities of the wavelet transform. Then, this estimate of the RFI signal is subtracted from the total received signal to obtain a RFI-mitigated noise signal. Statistical analysis helps to validate the mentioned methods.
Social Representations of Attention Deficit/Hyperactivity Disorder, 1988–1997

Considerable debate has arisen regarding many aspects of attention deficit/hyperactivity disorder (ADHD), including the existence, diagnosis and prevalence of the disorder, the use of medications in treating young children for the disorder, and the long-term side-effects of the medications. A fundamental catalyst in this debate involves the numerous and diverse social representations of ADHD: the differing ways of perceiving what ADHD is, whom it affects, and the most appropriate treatments. This paper presents a discussion of social representations theory and its previous applications to the study of mental illness, connecting this theory with research in media framing. Quantitative and qualitative content analyses of print media representations of ADHD over a ten-year period are presented. Using results from the media analysis, we examine different processes through which these representations might influence perceptions of individuals experiencing ADHD-related symptoms, particularly as these perceptions relate to mental health treatment decisions.
Scrib regulates HGF-mediated epithelial morphogenesis and is stabilized by Sgt1–HSP90

Summary Scribble was originally identified as a Drosophila protein that regulates epithelial polarity and formation of the basolateral surface. The mammalian orthologue, Scrib, is evolutionarily conserved, but does not appear to be necessary for apical-basolateral epithelial polarity. Instead, it is implicated in the regulation of cell survival, protein trafficking, adhesion and migration. A key issue is to understand the molecular pathway by which Scrib participates in these processes. We have investigated Scrib using a three-dimensional epithelial cell culture system. We show a novel association between the leucine-rich repeat domain of Scrib and the co-chaperone Sgt1 and demonstrate that these proteins are necessary for epithelial morphogenesis and tubulogenesis following hepatocyte growth factor (HGF) stimulation. The molecular chaperone HSP90 is also required for Sgt1 association with Scrib, and both Sgt1 and HSP90 are needed to ensure proper Scrib protein levels. Furthermore, reduced Scrib stability, following inhibition of Sgt1–HSP90, lowers the cellular abundance of the Scrib–&bgr;Pix–PAK complex. Inhibition of any member of this complex, Scrib, &bgr;Pix or PAK, is sufficient to block HGF-mediated epithelial morphogenesis. The identification of Scrib as an Sgt1–HSP90 client protein required for three-dimensional cell migration suggests that chaperone-mediated regulation of polarity protein stability and homeostasis is an unappreciated mechanism underlying dynamic rearrangements during morphogenesis.
Strategies of Rule Discovery in an Inference Task

It has long been known that subjects in certain inference tasks will seek evidence which can confirm their present hypotheses, even in situations where disconfirmatory evidence could be more informative. We sought to alter this tendency in a series of experiments which employed a rule discovery task, the 2-4-6 problem first described by Wason. The first experiment instructionally modified subjects confirmatory tendencies. While a disconfirmatory strategy was easily induced, it did not lead to greater efficiency in discovering the rule. The second experiment introduced subjects to the possibility of disconfirmation only after they had developed a strongly held hypothesis through the use of confirmatory evidence. This manipulation also failed to alter the efficiency of rule discovery. In the third experiment, subjects were taught to use multiple hypotheses at each step, in the manner of Platt's “Strong Inference”. This operation actually worsened performance. Finally, in the fourth experiment, the structure of the problem was altered slightly by asking subjects to seek two interrelated rules. A dramatic increase in performance resulted, perhaps because information which in previous tasks was seen as merely erroneous could now be related to an alternative rule. The four studies have broad implications for the psychological study of inference processes in general, and for the study of scientific inference in particular.
A new full-chip verification methodology to prevent CDM oxide failures

This paper describes a new full-chip CDM ESD verification method that enables the evaluation of complete integrated circuits (ICs) for CDM risk. We demonstrate that a robust analysis must comprehend millions of locations of driver-receiver (D/R) pairs on an IC, an accurate model of the grid resistance and an adequate representation of the CDM current distribution.
La RSE et les PME : Analyse descriptive à partir de l'enquête COI 2006

Cet article propose, a partir de l�enquete Changements organisationnels et informatisation (COI, 2006), d�etudier les pratiques de RSE des PME francaises comparees a celles des grandes entreprises. Les resultats montrent un moindre interet des PME aux enjeux RSE. En particulier, les pratiques sociales sont les plus divergentes entre les PME et les autres entreprises. Ces resultats mettent egalement en evidence un investissement differentiel en termes de RSE en fonction du secteur d�activite. Ils sont par la suite discutes au regard de l�investissement social responsable (ISR). En effet, ce dernier joue un role important comme levier d�action pour la diffusion des pratiques RSE.
Optimal power allocation for parallel Gaussian channels with LPD constraints

Low probability of detection (LPD) communication refers to reliable transmission of information that is difficult to detect by an unauthorised adversary. This paper studies LPD communication over parallel Gaussian channels, which are used to model a variety of communication scenarios. First a lower bound on the miss detection probability is derived assuming the adversary employs Neyman-Pearson hypothesis testing. It is shown that at low signal-to-noise ratio (SNR), the LPD constraint is equivalent to a constraint on the adversary's mean-square SNR. The optimal power allocation strategy that maximises the achievable number of transmitted information bits per codeword under constraints on the receiver's decoding error probability and the adversary's detection probability is analysed. Intuitively, it is shown that the optimal strategy favours channels where the receiver's noise power is low relative to that of the adversary's. Furthermore, as the block length increases, the optimal power allocation is simply a weighted version of the adversary's noise power profile, where the weights are the ratio of the adversary and receiver's noise power.
Diagnostic imaging of psoriatic arthritis. Part II: magnetic resonance imaging and ultrasonography

Abstract Plain radiography reveals specific, yet late changes of advanced psoriatic arthritis. Early inflammatory changes are seen both on magnetic resonance imaging and ultrasound within peripheral joints (arthritis, synovitis), tendons sheaths (tenosynovitis, tendovaginitis) and entheses (enthesitis, enthesopathy). In addition, magnetic resonance imaging enables the assessment of inflammatory features in the sacroiliac joints (sacroiliitis), and the spine (spondylitis). In this article, we review current opinions on the diagnostics of some selective, and distinctive features of psoriatic arthritis concerning magnetic resonance imaging and ultrasound and present some hypotheses on psoriatic arthritis etiopathogenesis, which have been studied with the use of magnetic resonance imaging. The following elements of the psoriatic arthritis are discussed: enthesitis, extracapsular inflammation, dactylitis, distal interphalangeal joint and nail disease, and the ability of magnetic resonance imaging to differentiate undifferentiated arthritis, the value of whole-body magnetic resonance imaging and dynamic contrast-enhanced magnetic resonance imaging.
THE RELATION OF PTYALIN CONCENTRATION TO THE DIET AND TO THE RATE OF SECRETION OF THE SALIVA

T HE ptyalin concentration in the various salivas was tested by the starch method. There was mixed with I/IO or ~/IO C.C. of saliva . 2j C.C. of I per cent boiled starch, and the rate of clearing of the starch solution, the rate of disappearance of the blue starch color on addition of iodine, and the rate of disappearance of the erythrodextrin determined. In this way we have three checks on the relative rate of digestion of the different saliva samples, and when all three correspond we are pretty certain to have an actual difference in ptyalin concentration. The advantages of this method are its simplicity and its relatively quick application. At the New York meeting of the American Physiological Society in December, 1906, Nielson l reported that forced diet of carbohydrates or sugar in man, even for a period of three or four days, greatly increases the ptyalin concentration in the mixed saliva. The same author had previously reported similar observations on the dog? Nielson’s results on the dog have not only not been confirmed by other observers (Mendel and Underhill,” Garrey,4 Carlson and Ryan 3, but it has been
Bilateral smoothing of gradient vector field and application to image segmentation

Medical image segmentation finds application in computer-aided diagnosis, computer-guided surgery, measuring tissue volumes, locating tumors, and pathologies. One approach to segmentation is to use active contours or snakes. Active contours start from an initialization (often manually specified) and are guided by image-dependent forces to the object boundary. Snakes may also be guided by gradient vector fields associated with an image. The first main result in this direction is that of Xu and Prince, who proposed the notion of gradient vector flow (GVF), which is computed iteratively. We propose a new formalism to compute the vector flow based on the notion of bilateral filtering of the gradient field associated with the edge map - we refer to it as the bilateral vector flow (BVF). The range kernel definition that we employ is different from the one employed in the standard Gaussian bilateral filter. The advantage of the BVF formalism is that smooth gradient vector flow fields with enhanced edge information can be computed noniteratively. The quality of image segmentation turned out to be on par with that obtained using the GVF and in some cases better than the GVF.
Deictic and Propositional Meaning—New Perspectives on Language in Schizophrenia

Emerging linguistic evidence points at disordered language behavior as a defining characteristic of schizophrenia. In this article, we review this literature and demonstrate how a framework focusing on two core functions of language—reference and propositional meaning—can conceptualize schizophrenic symptoms, identify important variables for risk assessment, diagnosis, and treatment, and inform cognitive behavioral therapy and other remedial approaches. We introduce the linguistic phenomena of deictic anchoring and propositional complexity, explain how they relate to schizophrenic symptoms, and show how they can be tracked in language behavior.
Shifting the Circadian Rhythm of Feeding in Mice Induces Gastrointestinal, Metabolic and Immune Alterations Which Are Influenced by Ghrelin and the Core Clock Gene Bmal1

Background In our 24-hour society, an increasing number of people are required to be awake and active at night. As a result, the circadian rhythm of feeding is seriously compromised. To mimic this, we subjected mice to restricted feeding (RF), a paradigm in which food availability is limited to short and unusual times of day. RF induces a food-anticipatory increase in the levels of the hunger hormone ghrelin. We aimed to investigate whether ghrelin triggers the changes in body weight and gastric emptying that occur during RF. Moreover, the effect of genetic deletion of the core clock gene Bmal1 on these physiological adaptations was studied. Methods Wild-type, ghrelin receptor knockout and Bmal1 knockout mice were fed ad libitum or put on RF with a normal or high-fat diet (HFD). Plasma ghrelin levels were measured by radioimmunoassay. Gastric contractility was studied in vitro in muscle strips and in vivo (13C breath test). Cytokine mRNA expression was quantified and infiltration of immune cells was assessed histologically. Results The food-anticipatory increase in plasma ghrelin levels induced by RF with normal chow was abolished in HFD-fed mice. During RF, body weight restoration was facilitated by ghrelin and Bmal1. RF altered cytokine mRNA expression levels and triggered contractility changes resulting in an accelerated gastric emptying, independent from ghrelin signaling. During RF with a HFD, Bmal1 enhanced neutrophil recruitment to the stomach, increased gastric IL-1α expression and promoted gastric contractility changes. Conclusions This is the first study demonstrating that ghrelin and Bmal1 regulate the extent of body weight restoration during RF, whereas Bmal1 controls the type of inflammatory infiltrate and contractility changes in the stomach. Disrupting the circadian rhythm of feeding induces a variety of diet-dependent metabolic, immune and gastrointestinal alterations, which may explain the higher prevalence of obesity and immune-related gastrointestinal disorders among shift workers.
Using the apparent diffusion coefficient to identifying MGMT promoter methylation status early in glioblastoma: importance of analytical method

Accurate knowledge of O6‐methylguanine methyltransferase (MGMT) gene promoter subtype in patients with glioblastoma (GBM) is important for treatment. However, this test is not always available. Pre‐operative diffusion MRI (dMRI) can be used to probe tumour biology using the apparent diffusion coefficient (ADC); however, its ability to act as a surrogate to predict MGMT status has shown mixed results. We investigated whether this was due to variations in the method used to analyse ADC.
Electricity consumption prediction based on Transformer-LSTM

The prediction of electricity consumption in the power system has always been an important task in the management of the power department. Propose a regional electricity consumption prediction model based on the combination of Transformer and Long Short Term Memory Network (LSTM). Firstly, the time dimension of the data is split and combined with other features as data features for electricity consumption prediction. Then, the input data is first passed through the Transformer encoding layer, then through the LSTM layer, and finally output is obtained through the linear layer. At the same time, a residual connection was added to concatenate the output and input features of the LSTM layer and input them into the linear layer. The experimental results show that the Transformer LSTM based prediction method exhibits excellent performance in predicting regional electricity consumption, providing a feasible and effective solution for managers when analyzing electricity consumption.
Constrained Model Predictive Control of spacecraft attitude with reaction wheels desaturation

In this paper we propose a Model Predictive Controller for spacecraft attitude tracking with reaction wheel actuators. The controller is designed for desaturation of the reaction wheels. In contrast with standard desaturation techniques, which rely on the activation of thrusters, the proposed strategy does not need to consume fuel as it exploits external torques derived from gravity gradients and/or the Earth magnetic field. The controller also guarantees that the spacecraft attitude is constrained within specified bounds during desaturation.
An empirical study of success factors on business-to-business e-marketplaces from buyers' and sellers' perspectives

This study tried to go a step further from the existing research framework, which is a TOE (technological, organizational and environmental perspectives) based model for technological innovation. The revised model is TOIM (technological, organizational, inter-organizational and marketplace perspectives). Additional variables such as trust (inter-organizational perspective), aggregation and service quality (marketplace perspective) were successfully tested for buyers and sellers in e-marketplaces. As the hypotheses for the new factors were supported, this research significantly contributed to further this line of research for the academics and has practical values for the participants in e-marketplaces.
Fibrous dysplasia-recent concepts

Fibrous dysplasia (FD) is a benign intramedullary fibro-osseous lesion. FD is a bone developmental anomaly characterized by replacement of normal bone and marrow bone by fibrous tissue. It involves any of the bones as single lesion (monostotic) or in multiple bone lesions (polyostotic) or all of the skeletal system (panostotic). Long bones are most commonly involved, which mostly identified incidentally and clinically appears asymptomatic. Clinical, radiographical and histopathological findings will help in confirming the lesion. There are many treatment option available, but still management of FD remains challenging.