Miracle-dz/UniFAR-FTUs huggingface dataset:
Photon-subtracted squeezed coherent state: nonclassicality and decoherence in thermal environment

We introduce the photon-subtracted squeezed coherent state (PSSCS), which is theoretically constructed by repeatedly subtracting photons from the squeezed coherent state (SCS) with squeezing parameter r and displacement amplitude α=|α|eiφ. Employing the normal ordering form of density operator of the SCS, we study the nonclassicality of the PSSCS by analyzing Mandel’s Q-parameter, quadratures squeezing, photon-number distribution (PND), and Wigner function (WF). We find that the PND in a PSSCS is a periodic function of φ with a period π and exhibits more remarkable oscillations than that of a SCS in the case of strong squeezing. The partial negative region of the WF is sensitive to r and |α|. The fidelity between PSSCS and SCS is analyzed, which manifests that larger photon subtraction number may result in lower fidelity. By virtue of the thermal entangled state representation the decoherence of the PSSCS in thermal environment is studied through the time evolution of the WF. The negative volume of the WF gradually diminishes with the increase of evolution time and thermal photon number, respectively. The study of the PSSCS shows that generating new photon-number-controllable nonclassical states from a weak coherent light may be realized by subtracting suitable photons from a SCS.
Singing in Co-Harmony: An Introduction to Trauma Informed Voice Care

Abstract:This article provides an overview of how trauma can impact the individuals that we work with, and offers strategies for creating a supportive environment within the context of voice care. Trauma-informed voice professionals aim to cultivate a supportive presence that has the ability to mindfully and imperfectly navigate both comfort and discomfort. We can begin this process by noticing our own physical and emotional sensations, and engaging in co-regulation (or co-harmony)—establishing compassionate, non-judgmental reciprocal connections. By acknowledging how trauma and chronic stress can manifest our bodies, we learn to hold more informed spaces for individuals to communicate with more ease, creativity, and authenticity.
A BAYESIAN APPROACH TO ESTIMATING AND FORECASTING ADDITIVE NONPARAMETRIC AUTOREGRESSIVE MODELS

We present a Bayesian approach for estimating nonparametrically an additive autoregressive model with the regression curve estimates cubic smoothing splines. Our approach is robust to innovation outliers; it can handle missing observations and produce multistep ahead forecasts. The computation is carried out using Markov chain Monte Carlo and requires O(nM) operations where n is the sample size and M is the number of Markov chain iterations. This makes it the first exact algorithm for spline smoothing of an additive autoregressive model which can handle large data sets. The properties of the estimates and forecasts are studied empirically using simulated and real data sets.
Intelligent electronic tongue system for the classification of genuine and false honeys

ABSTRACT Honey quality is a global concern since this product is highly susceptible to adulteration, given its competitive price. As a reliable strategy for honey authenticity determination, this work introduces an intelligent classification system that considers the pattern recognition point of view to develop an economical and quick analytical method to identify and differentiate genuine from adulterated honey. This work used an electronic tongue composed of three working electrodes of carbon, platinum, and gold. The system used Cyclic voltammetry to obtain data from 50 genuine and 50 adulterated honey samples. Subsequently, the system used multivariate data analysis using a pattern recognition methodology composed of three big stages, including data organization and normalization, dimensionality reduction, and k-Nearest Neighbors (k-NN) as a classification method. The process was validated with the Leave One Out Cross Validation technique (LOOCV), reaching a classification accuracy performance of 100%. The results show that it was possible the development of a combined methodology between analytical tools and chemometrics for an in-situ, quick and efficient authenticity honey evaluation.
Fibrin-Rhamnogalacturonan I Composite Gel for Therapeutic Enzyme Delivery to Intestinal Tumors

Therapy of colorectal cancer with protein drugs, including targeted therapy using monoclonal antibodies, requires the preservation of the drug’s structure and activity in the gastrointestinal tract or bloodstream. Here, we confirmed experimentally the fundamental possibility of creating composite protein–polysaccharide hydrogels based on non-degrading rhamnogalacturonan I (RG) and fibrin as a delivery vehicle for antitumor RNase binase. The method is based on enzymatic polymerization of fibrin in the presence of RG with the inclusion of liposomes, containing an encapsulated enzyme drug, into the gel network. The proposed method for fabricating a gel matrix does not require the use of cytotoxic chemical cross-linking agents and divalent cations, and contains completely biocompatible and biodegradable components. The process proceeds under physiological conditions, excluding the effect of high temperatures, organic solvents and ultrasound on protein components. Immobilization of therapeutic enzyme binase in the carrier matrix by encapsulating it in liposomes made from uncharged lipid made it possible to achieve its prolonged release with preservation of activity for a long time. The release time of binase from the composite carrier can be regulated by variation of the fibrin and RG concentration.
The Involvement of Cx43 in JNK1/2-Mediated Endothelial Mechanotransduction and Human Plaque Progression

Atherosclerotic lesions preferentially develop at bifurcations, characterized by non-uniform shear stress (SS). The aim of this study was to investigate SS-induced endothelial activation, focusing on stress-regulated mitogen-activated protein kinases (MAPK) and downstream signaling, and its relation to gap junction proteins, Connexins (Cxs). Human umbilical vein endothelial cells were exposed to flow (“mechanical stimulation”) and stimulated with TNF-α (“inflammatory stimulation”). Phosphorylated levels of MAPKs (c-Jun N-terminal kinase (JNK1/2), extracellular signal-regulated kinase (ERK), and p38 kinase (p38K)) were quantified by flow cytometry, showing the activation of JNK1/2 and ERK. THP-1 cell adhesion under non-uniform SS was suppressed by the inhibition of JNK1/2, not of ERK. Immunofluorescence staining and quantitative real-time PCR demonstrated an induction of c-Jun and c-Fos and of Cx43 in endothelial cells by non-uniform SS, and the latter was abolished by JNK1/2 inhibition. Furthermore, plaque inflammation was analyzed in human carotid plaques (n = 40) using immunohistochemistry and quanti-gene RNA-assays, revealing elevated Cx43+ cell counts in vulnerable compared to stable plaques. Cx43+ cell burden in the plaque shoulder correlated with intraplaque neovascularization and lipid core size, while an inverse correlation was observed with fibrous cap thickness. Our results constitute the first report that JNK1/2 mediates Cx43 mechanoinduction in endothelial cells by atheroprone shear stress and that Cx43 is expressed in human carotid plaques. The correlation of Cx43+ cell counts with markers of plaque vulnerability implies its contribution to plaque progression.
Cyclic relations and the Goldberg coefficients in the Campbell-Baker-Hausdorff formula

Recursively defined coefficients for the commutator-free form of the Campbell-Baker-Hausdorff formula are shown to apply to the commutator version of this formula, and a new relation on these coefficients is derived. Let x and y be noncommuting indeterminates over the rational numbers. The Campbell-Baker-Hausdorff formula asserts that exey ez, where z is a formal series in x and y with rational coefficients, and in fact that z is a Lie element, meaning that it may be written as a formal series in iterated commutators of x and y. (a) An attractive paper of Karl Goldberg published twenty-six years ago presents z as a commutator-free series in x and y:
Matrix Completion via Successive Low-rank Matrix Approximation

In this paper, a successive low-rank matrix approximation algorithm is presented for the matrix completion (MC) based on hard thresholding method, which approximate the optimal low-rank matrix from rank-one matrix step by step. The algorithm enables the distance between the matrix with the observed elements and the projection on low-rank manifold to be minimum. The optimal low-rank matrix with observed elements is obtained when the distance is zero. In theory, convergence and convergent error of the new algorithm are analyzed in detail. Furthermore, some numerical experiments show that the algorithm is more effective in CPU time and precision than the orthogonal rank-one matrix pursuit(OR1MP) algorithm and the augmented Lagrange multiplier (ALM) method when the sampling rate is low.
A Microfiber Cavity with Minimal-Volume Confinement

We demonstrate a type of microcavity with minimal-volume confinement using a high-contrast phase-shifted Bragg grating in a microfiber. While waveguiding by the air-silica boundary provides a diffraction-limited two-dimensional confinement, the grating introduces the third degree of confinement. Theoretical simulations verified the microfiber cavity confinement while the experimental demonstration, carried out in samples nanostructured by focused ion beam, showed a good agreement with theoretical predictions. This cavity can be used for a variety of applications ranging from sensing to quantum dynamic experiments.
Controlled electron injection in a laser-plasma accelerator

A few years ago, several experiments showed that laser-plasma accelerators can produce high-quality electron beams, with quasi-monoenergetic energy distributions at the 100 MeV level. These experiments were performed by focusing a single ultra-short and ultraintense laser pulse into an underdense plasma. Here, we report on recent experimental results of electron acceleration using two counter-propagating ultra-short and ultraintense laser pulses. We demonstrate that the use of a second laser pulse provides enhanced control over the injection and subsequent acceleration of electrons into plasma wakefields. The collision of the two laser pulses provides a pre-acceleration stage which provokes the injection of electrons into the wakefield. The experimental results show that the electron beams obtained in this manner are collimated (5 mrad divergence), monoenergetic (with relative energy spread <10%), tuneable (between 50 and 250 MeV) and, most importantly, stable.
An Optimized CoBRA Method for the Microfluidic Electrophoresis Detection of Breast Cancer Associated RASSF1 Methylation

Although breast cancer screening assays exist, many are inaccessible and have high turnaround times, leaving a significant need for better alternatives. Hypermethylation of tumor suppressor genes is a common epigenetic marker of breast cancer. Methylation tends to occur most frequently in the promoter and first exon regions of genes. Preliminary screening tests are crucial for informing patients whether they should pursue more involved testing. We selected RASSF1, previously demonstrated to be aberrantly methylated in liquid biopsies from breast cancer patients, as our gene of interest. Using CoBRA as our method for methylation quantification, we designed unique primer sets that amplify a portion of the CpG island spanning the 5′ end of the RASSF1 first exon. We integrated the CoBRA approach with a microfluidics-based electrophoresis quantification system (LabChip) and optimized the assay such that insightful results could be obtained without post-PCR purification or concentration, two steps traditionally included in CoBRA assays. Circumventing these steps resulted in a decreased turnaround time and mitigated the laboratory machinery and reagent requirements. Our streamlined technique has an estimated limit of detection of 9.1 ng/μL of input DNA and was able to quantify methylation with an average error of 4.3%.
Research on the Pose Error Compensation Technology for the Mass and Centroid Measurement of Large-Sized Aircraft Based on Kinematics

The accurate measurement of mass and centroid is indispensable for accurate control of aircraft. In order to eliminate the influence of assembly error and product pose error on the measurement results, a multi-station measurement idea that can self-compensate for the geometric parameter error is proposed in this paper based on. At the same time, the kinematic model of the mechanical structure of the measurement equipment is established to prove the effectiveness of the structure in error compensation theoretically, and the experimental verification of the standard part and aircraft is carried out. The test results show that the measurement results using the idea of the multi-station compensation measurement are significantly better than those of the more common methods, with the mass measurement accuracy of 0.03% and the centroid error within ±0.15 mm, meeting the requirement of high precision measurement for the mass properties.
Influence of core-shell interfaces on exciton and multi-exciton dynamics of CdSe-CdxZn1-xS quantum dots

Semiconductor quantum dots possess attractive optical properties useful in the photonic field. Thanks to the evolution of core-shell colloidal synthesis, quantum dots exhibit almost ideal emitting properties. Their employment in optoelectronic devices is encouraged by their size-tunable emission as well as by their high absorption cross-section and high photoluminescence quantum yield. In this work, starting from the archetypal CdSe based system, the influence of shell thickness and composition on exciton dynamics in CdSe/CdxZn1-xS core-shell QDs is investigated. By means of steadystate and transient optical spectroscopy, single- and multi-exciton recombination processes are characterized and correlated with different shell materials. The present study clarifies why graded CdSe-CdS-Cd0.5Zn0. 5-ZnS core-shell represents the best performing heterostructure for optical gain applications, since such quantum dots combine the high radiative rates of CdS with the superior confinement potential of ZnS in a single dot.
Mathematical model for soybean mosaic disease transmission with entomopathogen interventions and photoperiodicity

: Mosaic is a severe disease of soybeans that has the potential to reduce the quality and quantity of soybean production. The Mosaic disease can infect soybean plants by the Aphis vector carrying Soybean Mosaic Virus (SMV). In this study, a mathematical model of the spread of Mosaic disease was built by considering two interventions, namely the application of entomopathogen and the regulation of photosynthesis intensity. This research focuses on knowing the effect of intervention in controlling Mosaic disease and increasing the population of susceptible generative plants. Using dynamical system theory, non-endemic and endemic equilibrium points and their stability are obtained. Then, the basic reproduction ratio (ℜ 0 ) is obtained for this model. Sensitivity analysis was carried out to determine the most influential parameters in the model. Optimal control theory was used to determine the optimal conditions of the model by considering the cost of entomopathogen application and photoperiodicity. The results of numerical simulations show that the application of entomopathogen and photosynthetic intensity can suppress the population of plant and vector infections and increase the population of susceptible plants in the generative phase at the same time
RADIAL VELOCITIES AND SPECTRA OF FAINT BLUE STARS AT HIGH GALACTIC LATITUDES

Only fifteen years elapsed between the discovery by Humason and Zwicky of 48 faint blue stars near the Hyades and the North Galactic Pole and the recent publication of the catalog by Haro and Luyten of over 8000 blue stars brighter than m = 19 in the neighborhood of the South Galactic Pole. These blue stars are similar in color to the youngest stars of open clusters and the horizontal-branch stars of globular clusters, and are located at large distances from the galactic plane. In addition to the discovery programs for faint blue stars, studies of the Humason-Zwicky stars have been made by various investigators using low or moderate-dispersion spectra»»» and proper motions. »»»» A considerable number of photoelectric colors have been obtained. However, until now, little more is known about most of these faint blue stars—more than 10,000 have been listed—than the coordinates and rough estimates of the apparent magnitudes and colors. Only five percent of these stars are brighter than m = 16 ; the rest are accessible only with difficulty to spectrographic observations with present-day techniques and instruments. A still smaller proportion of them are bright enough to permit the use of old Carte du Ciel positions for the determination of their proper motions. The fragmentary data that we possess indicate, however, that we are concerned with a population whose characteristics differ from those of hot population I stars. Moreover, various observers have been able to recognize among them hot, type O and B, subdwarfs, sharp-line B or A stars similar to the bluest members of globular clusters, and a few white dwarfs, as well
The Mediating Effect of Presenteeism on the Relationship between Emotional Labor and Work Engagement of Coaches for Disability Sports

The aim of present study was to examine the mediating effect of presenteeism on the relationship between emotional labor and work engagement of coaches for disability sports. A total of 198 coaches in Korea participated in this study. Participants responded a survey measuring emotional labor, presenteeism, and work engagement. After analyzing the correlation between each variable, the mediation model was verified through structural equation model analysis. The results reveal that emotional labor of coaches for disability sports positively predicted their work engagement, but negatively predicted presenteeism. In addition, the participants’ presenteeism can have a negative effect on their work engagement. Moreover, completing work in presenteeism was found to mediate the relationship between the deep acting and surface acting in emotional labor and work engagement of disability sports coaches.
Double Model Following Adaptive Control for a Complex Dynamical Network

This paper formulates and solves a new problem of the double model following adaptive control (MFAC) of nodes and links in a complex dynamical network (CDN). This is different from most existing studies on CDN and MFAC. Inspired by the concept of composite systems, the CDN with dynamic links is regarded as an interconnected system composed of an interconnected node group (NG) and link group (LG). Guided by the above-mentioned new idea of viewing a CDN from the perspective of composite systems, by means of Lyapunov theory and proposed related mathematical preliminaries, a new adaptive control scheme is proposed for NG. In addition, to remove the restriction that the states of links in a CDN are unavailable due to physical constraints, technical restraints, and expensive measurement costs, we synthesize the coupling term in LG with the proposed adaptive control scheme for NG, such that the problem of double MFAC of nodes and links in CDN is solved. Finally, a simulation example is presented to verify the theoretical results.
Rhanteriol, a New Rhanterium suaveolens Desf. Lignan with Pharmacological Potential as an Inhibitor of Enzymes Involved in Neurodegeneration and Type 2 Diabetes

Several specialized plant metabolites are reported to be enzyme inhibitors. In this investigation, the phytochemical composition and the biological activity of Rhanterium suaveolens Desf. were studied. One new lignan (rhanteriol 1) and seven known secondary metabolites were isolated from the aerial parts of R. suaveolens by using different chromatographic procedures. The biological properties of the R. suaveolens extracts and the new compound were evaluated by measuring their ability to inhibit the cholinesterase and carbohydrate-hydrolyzing enzymes, using cell-free in vitro methods. The new lignan, rhanteriol, was shown to inhibit α-amylase and α-glucosidase (IC50 = 46.42 ± 3.25 μM and 26.76 ± 3.29 μM, respectively), as well as butyrylcholinesterase (IC50 = 10.41 ± 0.03 μM), with an effect comparable to that of the respective standards, acarbose and galantamine. Furthermore, docking studies were performed suggesting the interaction mode of rhanteriol with the active sites of the investigated enzymes. The obtained data demonstrated that the aerial part of R. suaveolens could represent a source of active molecules, such as rhanteriol, usable in the development of treatments for preventing or treating type 2 diabetes mellitus and neurodegeneration.
Effects of notch shape on the magnetic domain wall motion in nanowires with in-plane or perpendicular magnetic anisotropy

Magnetic domain walls (DWs) in nanowires have been extensively investigated for potential applications in spintronic devices. For the precise storage of magnetic data, the control of DW pinning and depinning is critical. Here, we report upon the micromagnetic modeling results of the DW motion behaviors in notched or anti-notched nanowires possessing in-plane magnetic anisotropy (IMA) or perpendicular-to-the-plane magnetic anisotropy (PMA). In the nanowires with IMA, the energy of the DW in nanowires with anti-notches was lower compared to that of the nanowires with normal notches. Easier DW depinning motions were observed in the anti-notched nanowires. Unlike in the IMA case, the DW energy in the nanowires with PMA was lower with normal notches. Thus, the DW was able to move faster and easier through the normal notches compared to the anti-notches in the nanowire with the PMA at the same current density.
Effect of Sarecycline on the Acne Symptom and Impact Scale and Concerns in Moderate-to-Severe Truncal Acne in Open-Label Pilot Study

Truncal acne is common, and the psychosocial burden may be underestimated as patients most often complain of facial acne. The Acne Symptom and Impact Scale (ASIS) is a 17-item patient-reported outcome (PRO) measure designed to assess the signs and impacts of acne vulgaris. ASIS has previously been validated in a prospective, non-interventional study as a reliable PRO instrument for facial acne. In a pilot study, ASIS, and an additional 10 new questions that focused on the concerns of patients (ASIS-C), were given to 10 patients with moderate-to-severe truncal acne vulgaris who received 3 months of monotherapy with oral sarecycline, a narrow-spectrum tetracycline-class antibiotic. ASIS-C questionnaires were also given to 10 acne-free control subjects. Average ASIS-C answers decreased by 4% for Signs, 15% for Impact, and 16% for Concerns in the 10 patients, with greater decreases of 5% for Signs, 20% for Impact, and 19% for Concerns in the 60% of patients whose truncal acne was clear or almost clear after 12 weeks of sarecycline treatment. In this study, sarecycline was effective in reducing the psychosocial burden associated with truncal acne based on the ASIS-C PRO measures.