Miracle-dz/UniFAR-FTUs huggingface dataset:
Optimal Configuration of Redundant Inertial Sensors for Navigation and FDI Performance

This paper considers the optimal sensor configuration for inertial navigation systems which have redundant inertial sensors such as gyroscopes and accelerometers. We suggest a method to determine the optimal sensor configuration which considers both the navigation and FDI performance. Monte Carlo simulations are performed to show the performance of the suggested optimal sensor configuration method.
Development of mechanical coupling for piezoelectric energy harvester adapted to low-frequency vibration

Piezoelectric cantilever is widely use as energy harvester from vibration source. Common of the problem is how to tune the natural frequency of piezoelectric in order to generate maximum ouput power. This work was proposed alternative scheme of mechanical coupling for tune the vibration input into natural frequency of piezoelectric, that consist of cantilever beam and permanent magnet. On the experiment, correlation with the lenght of cantilever beam and the output power are evaluated. Based on experiment, the maximum ouput power could be reached when the length of cantilever beam is twice of the length of the piezoelectric dimension.
Profissões e identidades profissionais

Na medida em que todas as obras da UC Digitalis se encontram protegidas pelo Código do Direito de Autor e Direitos Conexos e demais legislação aplicável, toda a cópia, parcial ou total, deste documento, nos casos em que é legalmente admitida, deverá conter ou fazer-se acompanhar por este aviso. Profissões e identidades profissionais Autor(es): Santos, Clara Cruz Publicado por: Imprensa da Universidade de Coimbra URL persistente: URI:http://hdl.handle. net/10316.2/2654 DOI: DOI:http://dx.doi. org/10.14195/978-989-26-0237-0
Pairs of SAT Assignments and Clustering in Random Boolean Formulae

We investigate geometrical properties of the random K-satisfiability problem. For large enough K, we prove that there exists a region of clause density, below the satisfiability threshold, where SAT assignments are grouped into well separated clusters. This confirms the validity of the clustering scenario which is at the heart of the recent heuristic analysis of satisfiability using statistical physics analysis (the cavity method), and its algorithmic counterpart (the survey propagation algorithm). Our method relies on the study of pairs of SAT-assignments at a fixed distance. It uses elementary probabilistic arguments (first and second moment methods), and might be useful in other problems of computational and physical interest where similar phenomena appear.
Globalisation , Productivity and Technology Research Paper 2005 / 01 Acquisition FDI and the Export Intensity of Multinational Firms

This paper investigates the impact of acquisition FDI on exporting intensity in U.K manufacturing. A quasi-likelihood estimation method is used, and the empirical estimates point to the following conclusions: (i) UK firms with higher exporting intensity are more likely to be foreign takeover targets; (ii) US acquired firms increase their exporting intensity, consistent with the idea that acquisition FDI is used as a platform for serving the wider EU market (iii) Firms acquired by European multinationals significantly decrease their export-orientation, suggesting targeting of the domestic market post-takeover; (iv) The exporting propensity of non-US and non-EU multinationals exhibits no significant change. JEL classification: F14, F23
Intra- and Interspecific Variation in Primate Gene Expression Patterns

Although humans and their closest evolutionary relatives, the chimpanzees, are 98.7% identical in their genomic DNA sequences, they differ in many morphological, behavioral, and cognitive aspects. The underlying genetic basis of many of these differences may be altered gene expression. We have compared the transcriptome in blood leukocytes, liver, and brain of humans, chimpanzees, orangutans, and macaques using microarrays, as well as protein expression patterns of humans and chimpanzees using two-dimensional gel electrophoresis. We also studied three mouse species that are approximately as related to each other as are humans, chimpanzees, and orangutans. We identified species-specific gene expression patterns indicating that changes in protein and gene expression have been particularly pronounced in the human brain.
Toxic release inventories and green consumerism: empirical evidence from Canada

Do firms abate pollution in response to actual or anticipated green consumerism? Lacking direct observational data on the extent of green consumerism, we construct an indirect method to elicit its effect on pollution abatement. If environmentally motivated consumers target companies rather than particular facilities of a multi-product firm, green consumerism can be identified through intra-firm inter-plant spillover effects in pollution abatement. We test the prediction that `environmentally-leveraged' firms with consumer market exposure experience larger emission reductions. We use 1993-99 panel data from Canada's National Pollutant Release Inventory (NPRI), with pollutants adjusted for toxicity. Our empirical results find statistically significant evidence of green consumerism, but its economic magnitude is very small.
High spatial resolution subsurface microscopy

We present a high-spatial-resolution subsurface microscopy technique that significantly increases the numerical aperture of a microscope without introducing an additional spherical aberration. Consequently, the diffraction-limited spatial resolution is improved beyond the limit of standard subsurface microscopy. By realizing a numerical aperture of 3.4, we experimentally demonstrate a lateral spatial resolution of better than 0.23 μm in subsurface inspection of Si integrated circuits at near infrared wavelengths.
Badminton injuries.

In a one year period, from 1 January 1986 to 31 December 1986, 4303 patients with sports injuries were treated at Aarhus Amtssygehus and Aarhus Kommunehospital. The mean age was 21.6 years (range 7-72 years) and 2830 were men. Two hundred and seventeen badminton injuries occurred in 208 patients (136 men) with a mean age of 29.6 years (range 7-57 years), constituting 4.1 percent of all sport injuries in Aarhus. Joints and ligaments were injured in 58.5 percent of the patients, most frequently located in the lower limb and significantly more often among patients younger than 30 years of age. Muscle injury occurred in 19.8 percent of the patients. This type of injury was significantly more frequent among patients older than 30 years of age. Most injuries were minor. However, 6.8 percent of the patients were hospitalized and 30.9 percent received additional treatment by a physician. As the risk of injury varies with age, attempts to plan training individually and to institute prophylactic measures should be made.
Optimization of task allocation and priority assignment in hard real-time distributed systems

The complexity and physical distribution of modern active safety, chassis, and powertrain automotive applications requires the use of distributed architectures. Complex functions designed as networks of function blocks exchanging signal information are deployed onto the physical HW and implemented in a SW architecture consisting of a set of tasks and messages. The typical configuration features priority-based scheduling of tasks and messages and imposes end-to-end deadlines. In this work, we present and compare formulations and procedures for the optimization of the task allocation, the signal to message mapping, and the assignment of priorities to tasks and messages in order to meet end-to-end deadline constraints and minimize latencies. Our formulations leverage worst-case response time analysis within a mixed integer linear optimization framework and are compared for performance against a simulated annealing implementation. The methods are applied for evaluation to an automotive case study of complexity comparable to industrial design problems.
A Viral Ubiquitin Ligase Has Substrate Preferential SUMO Targeted Ubiquitin Ligase Activity that Counteracts Intrinsic Antiviral Defence

Intrinsic antiviral resistance represents the first line of intracellular defence against virus infection. During herpes simplex virus type-1 (HSV-1) infection this response can lead to the repression of viral gene expression but is counteracted by the viral ubiquitin ligase ICP0. Here we address the mechanisms by which ICP0 overcomes this antiviral response. We report that ICP0 induces the widespread proteasome-dependent degradation of SUMO-conjugated proteins during infection and has properties related to those of cellular SUMO-targeted ubiquitin ligases (STUbLs). Mutation of putative SUMO interaction motifs within ICP0 not only affects its ability to degrade SUMO conjugates, but also its capacity to stimulate HSV-1 lytic infection and reactivation from quiescence. We demonstrate that in the absence of this viral countermeasure the SUMO conjugation pathway plays an important role in mediating intrinsic antiviral resistance and the repression of HSV-1 infection. Using PML as a model substrate, we found that whilst ICP0 preferentially targets SUMO-modified isoforms of PML for degradation, it also induces the degradation of PML isoform I in a SUMO modification-independent manner. PML was degraded by ICP0 more rapidly than the bulk of SUMO-modified proteins in general, implying that the identity of a SUMO-modified protein, as well as the presence of SUMO modification, is involved in ICP0 targeting. We conclude that ICP0 has dual targeting mechanisms involving both SUMO- and substrate-dependent targeting specificities in order to counteract intrinsic antiviral resistance to HSV-1 infection.
What paves the way to conventional language? The predictive value of babble, pointing and SES.

A child’s first words mark the emergence of a uniquely human ability. Theories of the developmental steps that pave the way for word production have proposed that either vocal or gestural precursors are key. These accounts were tested by assessing the developmental synchrony in the onset of babbling, pointing and word production for 46 infants observed monthly between the ages of 9 and 18 months. Babbling and pointing did not develop in tight synchrony and babble onset alone predicted first words. Pointing and maternal education emerged as predictors of lexical knowledge only in relation to a measure taken at 18months. This suggests a far more important role for early phonological development in the creation of the lexicon than previously thought.
Type II compactifications on manifolds with SU(2) × SU(2) structure

We study compactifications of type II theories on SU(2) × SU(2) structure manifolds to six, five and four spacetime dimensions. We use the framework of generalized geometry to describe the NS-NS sector of such compactifications and derive the structure of their moduli spaces. We show that in contrast to SU(3) × SU(3) structure compactifications, there is no dynamical SU(2) × SU(2) structure interpolating between an SU(2) structure and an identity structure. Furthermore, we formulate type II compactifications on SU(2) × SU(2) structures in the context of exceptional generalized geometry which makes the U-duality group manifest and naturally incorporates the scalar degrees of freedom arising in the Ramond-Ramond sector. Via this formalism we derive the structure of the moduli spaces as it is expected from N = 4 supergravity.
Molecular cloning of amphiglycan, a novel integral membrane heparan sulfate proteoglycan expressed by epithelial and fibroblastic cells

We have synthesized an antisense oligonucleotide primer that matches a supposedly conserved sequence in messages for heparan sulfate proteoglycans with transmembrane orientations. With the aid of this primer we have amplified partial and selected full-length copies of a message from human lung fibroblasts that codes for a novel integral membrane heparan sulfate proteoglycan. The encoded protein is 198 amino- acids long, with discrete cytoplasmic, transmembrane, and amino- terminal extracellular domains. Except for the sequences that represent putative heparan sulfate chain attachment sites, the extracellular domain of this protein has a unique structure. The transmembrane and cytoplasmic domains, in contrast, are highly similar to the corresponding domains of fibroglycan and syndecan, the two cell surface proteoglycans that figured as models for the design of the antisense primer. This similarity includes the conservation of four tyrosine residues, one immediately in front of the stop transfer sequence and three in the cytoplasmic segment, and of the most proximal and most distal cytoplasmic sequences. The cDNA detects a single 2.6-kb message in cultured human lung fibroblasts and in a variety of human epithelial and fibroblastic cell lines. Polyclonal and monoclonal antibodies raised against the encoded peptide after expression as a beta- galactosidase fusion protein react with the 35-kD coreprotein of a cell surface heparan sulfate proteoglycan of human lung fibroblasts and decorate the surface of many cell types. We propose to name this proteoglycan "amphiglycan" (from the Greek words amphi, "around, on both sides of" and amphoo, "both") referring to its domain structure which extends on both sides of the plasmamembrane, and to its localization around cells of both epithelial and fibroblastic origin.
Metformin use and improved response to therapy in rectal cancer

Locally advanced rectal cancer is commonly treated with chemoradiation prior to total mesorectal excision (TME). Studies suggest that metformin may be an effective chemopreventive agent in this disease as well as a possible adjunct to current therapy. In this study, we examined the effect of metformin use on pathologic complete response (pCR) rates and outcomes in rectal cancer. The charts of 482 patients with locally advanced rectal adenocarcinoma treated from 1996 to 2009 with chemoradiation and TME were reviewed. Median radiation dose was 50.4 Gy (range 19.8–63). Nearly, all patients were treated with concurrent 5‐fluorouracil‐based chemotherapy (98%) followed by adjuvant chemotherapy (81.3%). Patients were categorized as nondiabetic (422), diabetic not taking metformin (40), or diabetic taking metformin (20). No significant differences between groups were found in clinical tumor classification, nodal classification, tumor distance from the anal verge or circumferential extent, pretreatment carcinoembryonic antigen level, or pathologic differentiation. pCR rates were 16.6% for nondiabetics, 7.5% for diabetics not using metformin, and 35% for diabetics taking metformin, with metformin users having significantly higher pCR rates than either nondiabetics (P = 0.03) or diabetics not using metformin (P = 0.007). Metformin use was significantly associated with pCR rate on univariate (P = 0.05) and multivariate (P = 0.01) analyses. Furthermore, patients taking metformin had significantly increased disease‐free (P = 0.013) and overall survival (P = 0.008) compared with other diabetic patients. Metformin use is associated with significantly higher pCR rates as well as improved survival. These promising data warrant further prospective study.
Physical inactivity is associated with lower forced expiratory volume in 1 second : European Prospective Investigation into Cancer-Norfolk Prospective Population Study.

Forced expiratory volume in 1 second (FEV(1)) is a strong risk factor for cardiovascular disease, stroke, lung cancer, and all-cause mortality. One possible explanation for this association is that FEV(1) is a marker of other determinants of mortality risk, such as obesity and physical inactivity. In a population-based cohort study of 12,283 men and women aged 45-74 years from the European Prospective Investigation into Cancer-Norfolk Study recruited in 1993-1997, the cross-sectional association between physical activity and FEV(1) and that between physical activity and change in FEV(1) were analyzed. Indices of physical activity, including participation in vigorous recreational activity, stair climbing, and television viewing, were assessed with a validated questionnaire designed to assess activity in the previous year. Television viewing was negatively associated with FEV(1) in men and women (p < 0.001), whereas stair climbing and participation in vigorous leisure time activities were positively associated with FEV(1) in men and women (p < 0.001). The associations remained after adjustment for known confounders, including age, height, vitamin C, and smoking. Climbing more stairs and participating in vigorous leisure-time activity predicted a slower rate in annual percent decline in FEV(1) (p < 0.004 and p < 0.002, respectively). In conclusion, physical activity is associated with higher levels of FEV(1), whereas television viewing is associated with lower levels.
Frontiers of a paradigm: exploring human computation with digital games

Each day millions of people play digital games with different motivations. These motivations rang from time beating to deep immersion into a narration or interacting with a community. To address all these different means, a range of game designs is necessary. Traditional human computation games cannot present all these aspects yet. This work will give a game centered view on game design for human computation. To demonstrate the value of this view it will present a fast-paced action game called OnTo-Galaxy along with two different human computation tasks.
0 System Overview The Language Processing Modules in Verbmobil Recognition Prosody Synsem Transfer Generation Synthesis Context Dialogue ́

Verbmobil is a speech-to-speech translation system for spontaneous dialogues. It provides mobile phone users with simultaneous dialogue translation services in English, German and Japanese for restricted topics. These topics are appointment scheduling, travel planning and remote PC maintenance. The system is special in that it mediates a dialogue by continuously monitoring and processing the participants input. Using a dialogue memory and respective domain knowledge it provides context-sensitive translations following the dialogue in any direction. In this paper I will present parts of the Verbmobil system, which together make context tracking possible. The review and study is done in the frame of the course Dialogue Systems held by Lars Ahrenberg within GSLT in the spring 2002.
Sufficient Condition on the Fractional Integral for the Convergence of a Function

A sufficient condition on the fractional integral of the absolute value of a function is given in this paper, which allows to assure the convergence of the function to zero. This result can be useful to assure the convergence of a function when it is hard to know its exact evolution, but conditions on its fractional integral can be stated.
Convergence of MAP kinase pathways on the ternary complex factor Sap‐1a

The serum response element (SRE), which is pivotal for transcriptional up‐regulation of the c‐fos proto‐oncogene, is constitutively occupied by a protein complex comprising the serum response factor and a ternary complex factor (TCF). Phosphorylation of the TCFs Elk‐1 and Sap‐1a by the ERK and JNK subclasses of MAP kinases triggers c‐fos transcription. We demonstrate here that Elk‐1 is barely activated by a third subclass of MAP kinases (p38), most likely because the critical residues Ser383 and Ser389 are poorly phosphorylated by p38 MAP kinase. In contrast, the TCF Sap‐1a is efficiently phosphorylated by p38 MAP kinase in vitro and in vivo on the homologous residues Ser381 and Ser387. Mutation of these sites to alanine severely reduces c‐fos SRE‐dependent transcription mediated by Sap‐1a and p38 MAP kinase. Thus, Sap‐1a may be an important target for mitogens, stress and apoptotic signals to elicit a nuclear response. However, signaling from p38 MAP kinase to Sap‐1a or from Sap‐1a to the basal transcription machinery does not occur in all cell types nor at promoters other than the c‐fos SRE, which may ensure the specificity of signaling.
Growing self-leaders: the role of motivating language

Purpose This paper aims to examine how leader communication can help foster an employee’s ability to set and achieve goals and align these goals with organizationally relevant purposes. Design/methodology/approach To better understand this process, the authors use two well-supported theories – motivating language to provide a framework for understanding leader communication and self-leadership to examine employee goal setting. Findings Examining these two theories together has resulted in a practical, theory-based guide for how managers can use leader communication to improve workplace results. Originality/value This paper offers researchers a new lens through which to view workplace practices in organizations driven by innovation and knowledge management, and a framework for managers and consultants to develop methods for inspiring and guiding workers toward improved organizational performance.
Layered Encoding and Transmission of Video in Heterogeneous Environments

for real-time video transmission in heterogeneous network and computing environments, like the Internet, need to be highly scalable and adaptive in terms of bandwidth and processing requirements. Layered video encodings in combination with layered transmission schemes have been proposed as a solution to network and terminal equipment heterogeneity. In this paper we identify the fundamental requirements of layered video encoding and transmission architectures, and review the different types of layering mechanisms available. Two applications are emphasized: multipoint videoconferencing and point-to-point video streaming. The implications of layer granularity for network bandwidth utilization are experimentally investigated through simulations.
Coordinated plasticity in brainstem and auditory cortex contributes to enhanced categorical speech perception in musicians

Musicianship is associated with neuroplastic changes in brainstem and cortical structures, as well as improved acuity for behaviorally relevant sounds including speech. However, further advance in the field depends on characterizing how neuroplastic changes in brainstem and cortical speech processing relate to one another and to speech‐listening behaviors. Here, we show that subcortical and cortical neural plasticity interact to yield the linguistic advantages observed with musicianship. We compared brainstem and cortical neuroelectric responses elicited by a series of vowels that differed along a categorical speech continuum in amateur musicians and non‐musicians. Musicians obtained steeper identification functions and classified speech sounds more rapidly than non‐musicians. Behavioral advantages coincided with more robust and temporally coherent brainstem phase‐locking to salient speech cues (voice pitch and formant information) coupled with increased amplitude in cortical‐evoked responses, implying an overall enhancement in the nervous system's responsiveness to speech. Musicians' subcortical and cortical neural enhancements (but not behavioral measures) were correlated with their years of formal music training. Associations between multi‐level neural responses were also stronger in musically trained listeners, and were better predictors of speech perception than in non‐musicians. Results suggest that musicianship modulates speech representations at multiple tiers of the auditory pathway, and strengthens the correspondence of processing between subcortical and cortical areas to allow neural activity to carry more behaviorally relevant information. We infer that musicians have a refined hierarchy of internalized representations for auditory objects at both pre‐attentive and attentive levels that supplies more faithful phonemic templates to decision mechanisms governing linguistic operations.