Miracle-dz/UniFAR-FTUs huggingface dataset:
Comparative Evaluation of Coronally Advanced Flap with Modified Coronally Advanced Flap in the Management of Gingival Recession: A Randomized Clinical Trial

Gingival recession is one of the most common esthetic concerns associated with periodontal tissues. As the conventional technique of coronally advanced flap ends up with different disadvantages, a modified technique has been introduced to overcome the limitations. Thus, the two techniques has been planned to compare and evaluate. The study was conducted on 11 randomly selected subjects. In phase I, scaling was done and in phase II, coronally advanced flap technique in control group and modified coronally advanced flap technique in test group was done. Clinical attachment level, probing pocket depth, keratinized tissue width, length and width of recession, pain and healing index was assessed. Results showed a statistically significant reduction in pain index scores, clinical attachment level scores, probing depth scores, recession length and width scores in both the groups were observed. Also, statistically significant increase in healing index scores and keratinized tissue width scores were observed on intragroup comparison. However, on intergroup comparison, test group revealed better results as compared to control group in all the parameters. Thus, from the observation, it was concluded that both the groups has better clinical outcomes but test group showed better results in all the clinical parameters as compared to control group.
FLORISTIC INVENTORY AND ETHNOBOTANICAL STUDY OF THE NALTAR VALLEY (KARAKORAM RANGE), GILGIT, PAKISTAN

Naltar valley has diverse range of flora inhabiting some natural population of endemic plants listed as endangered category. The present study was carried out to record ethnobotanical uses of plants by local inhabitants of the Naltar Valley during summer 2009-11. The detailed information was gathered from the native herbal healers (Hakeems), shepherds and midwives (Daai) by using open ended questionnaire. Global Positioning System (GPS) was used to record coordinates of the 46 localities and their distribution map was designed by using ArcGis 9.3. In all, 141 plant species belonging to 107 genera and 48 families were found in practice by the natives for fulfilling their daily life requirements. The reported ethnoflora were comprised of 91 herbs and 23 shrubs. The highest numbers of species (133) were used for medicinal purpose, followed by fodder and forage (101 spp.), fuel and timber (37 spp.), ethnoveterinary uses (27 spp.) and miscellaneous (10 spp.). With reference to medicinal plants, 133 species were used in treating 48 different diseases/ailments by the local herbalists. Family Importance Value (FIV) indicated that Asteraceae was the most dominant (12.06%), followed by Fabaceae (7.09%), Polygonaceae and Rosaceae (7.67% each), while rest of the families had fewer species. The natural ecosystem is declining at rapid pace due to over harvesting coupled with overgrazing and un-sustainable management of flora causing threat to local biodiversity and need a comprehensive plan to protect natural resources.
The Characterization and Cytotoxic Evaluation of Chondrosia reniformis Collagen Isolated from Different Body Parts (Ectosome and Choanosome) Envisaging the Development of Biomaterials

Chondrosia reniformis is a collagen-rich marine sponge that is considered a sustainable and viable option for producing an alternative to mammalian-origin collagens. However, there is a lack of knowledge regarding the properties of collagen isolated from different sponge parts, namely the outer region, or cortex, (ectosome) and the inner region (choanosome), and how it affects the development of biomaterials. In this study, a brief histological analysis focusing on C. reniformis collagen spatial distribution and a comprehensive comparative analysis between collagen isolated from ectosome and choanosome are presented. The isolated collagen characterization was based on isolation yield, Fourier-transformed infrared spectroscopy (FTIR), circular dichroism (CD), SDS-PAGE, dot blot, and amino acid composition, as well as their cytocompatibility envisaging the development of future biomedical applications. An isolation yield of approximately 20% was similar for both sponge parts, as well as the FTIR, CD, and SDS-PAGE profiles, which demonstrated that both isolated collagens presented a high purity degree and preserved their triple helix and fibrillar conformation. Ectosome collagen had a higher OHpro content and possessed collagen type I and IV, while the choanosome was predominately constituted by collagen type IV. In vitro cytotoxicity assays using the L929 fibroblast cell line displayed a significant cytotoxic effect of choanosome collagen at 2 mg/mL, while ectosome collagen enhanced cell metabolism and proliferation, thus indicating the latter as being more suitable for the development of biomaterials. This research represents a unique comparative study of C. reniformis body parts, serving as a support for further establishing this marine sponge as a promising alternative collagen source for the future development of biomedical applications.
Tropical cyclone rainfall structure affecting indochina peninsula and lower mekong river basin (LMB)

Indochina Peninsula is located in between Bay of Bengal (BoB) and South-China Sea (SCS). This region is affected frequently from Tropical Cyclones (TCs) formed in North Indian Ocean (NIO), South-China Sea (SCS), and North West Pacific Ocean (NWP). This research analyzed the structure of the rainfall over Indochina Peninsula and its relationships with TCs from the aforementioned sources. Principle Component Analysis (PCA) was performed to investigate the dominant rainfall area produced from those TCs. Spatial and Temporal structures of rainfall from the TCs is analyzed to understand their propagation. The results show that the dominant TC rainfall area covers Central Vietnam which contributed around 25% to total rainfall in the region. However, the contribution of this TC rainfall over LMB is likely less than 20% where Laos's territory receives highest contribution (20%). Furthermore, from the three source areas, TCs formed in SCS produce the highest rain rate when they develop into typhoon intensity stage of Joint Typhoon Warning Center (JTWC)’s scale. The average duration of TC rainfall over Indochina Peninsula is 81.28 hours, and over LMB is 66.22 hours. Thus, same as other regions in the Indochina Peninsula, LMB is affected by TC rainfall with considerable scales both spatially and temporally that may lead to significant hydrometeorological hazards.
A Systematic Literature Review of Deep Learning Approaches for Sketch-Based Image Retrieval: Datasets, Metrics, and Future Directions

Sketch-based image retrieval (SBIR) utilizes sketches to search for images containing similar objects or scenes. Due to the proliferation of touch-screen devices, sketching has become more accessible and therefore has received increasing attention. Deep learning has emerged as a potential tool for SBIR, allowing models to automatically extract image features and learn from large amounts of data. To the best of our knowledge, there is currently no systematic literature review (SLR) of SBIR with deep learning. Therefore, the aim of this review is to incorporate related works into a systematic study, highlighting the main contributions of individual researchers over the years, with a focus on past, present and future trends. To achieve the purpose of this study, 90 studies from 2016 to June 2023 in 4 databases were collected and analyzed using the Preferred Reporting Items for Systematic reviews and Meta-Analyses (PRISMA) framework. The specific models, datasets, evaluation metrics, and applications of deep learning in SBIR are discussed in detail. This study found that Convolutional Neural Networks (CNN) and Generative Adversarial Networks (GAN) are the most widely used deep learning methods for SBIR. A commonly used dataset is Sketchy, especially in the latest Zero-shot sketch-based image retrieval (ZS-SBIR) task. The results show that Mean Average Precision (mAP) is the most commonly used metric for quantitative evaluation of SBIR. Finally, we provide some future directions and guidance for researchers based on the results of this review.
Rett Syndrome and the Role of MECP2: Signaling to Clinical Trials

Rett syndrome (RTT) is a neurological disorder that mostly affects females, with a frequency of 1 in 10,000 to 20,000 live birth cases. Symptoms include stereotyped hand movements; impaired learning, language, and communication skills; sudden loss of speech; reduced lifespan; retarded growth; disturbance of sleep and breathing; seizures; autism; and gait apraxia. Pneumonia is the most common cause of death for patients with Rett syndrome, with a survival rate of 77.8% at 25 years of age. Survival into the fifth decade is typical in Rett syndrome, and the leading cause of death is cardiorespiratory compromise. Rett syndrome progression has multiple stages; however, most phenotypes are associated with the nervous system and brain. In total, 95% of Rett syndrome cases are due to mutations in the MECP2 gene, an X-linked gene that encodes for the methyl CpG binding protein, a regulator of gene expression. In this review, we summarize the recent developments in the field of Rett syndrome and therapeutics targeting MECP2.
Impact of oxygen ordering on titanium lattice parameters

Variations with oxygen concentration of titanium lattice parameters are obtained by means of ab initio calculations, considering the impact of oxygen ordering. The quasiharmonic approximation is used to take into account the thermal expansion at finite temperature. Results show that lattice parameters depend mainly on oxygen concentration and, to a lesser extent, on the ordering state. Knowing these theoretical variations, one can get insights into the composition of ordered compounds existing in Ti-O binary alloys from their lattice mismatch measured experimentally by x-ray diffraction. The approach is used in a binary alloy containing 6000 ppm in weight of oxygen. It is concluded that the ordered compounds, which are observed after a recrystallization heat treatment, do not have the expected Ti6O stoichiometry but have a composition close to the nominal concentration. Oxygen ordering proceeds, therefore, before oxygen partitioning in titanium.
Acidic Urine pH and Clinical Outcome of Lower Urinary Tract Infection in Kidney Transplant Recipients Treated with Ciprofloxacin and Fosfomycin

Different factors, including antimicrobial resistance, may diminish the effectiveness of antibiotic therapy, challenging the management of post-transplant urinary tract infection (UTI). The association of acidic urine pH with microbiological and clinical outcomes was evaluated after fosfomycin or ciprofloxacin therapy in 184 kidney transplant recipients (KTRs) with UTI episodes by Escherichia coli (N = 115) and Klebsiella pneumoniae (N = 69). Initial urine pH, antimicrobial therapy, and clinical and microbiological outcomes, and one- and six-month follow-up were assessed. Fosfomycin was prescribed in 88 (76.5%) E. coli and 46 (66.7%) K. pneumoniae UTI episodes in the total cohort. When the urine pH ≤ 6, fosfomycin was prescribed in 60 (52.2%) E. coli and 29 (42.0%) K. pneumoniae. Initial urine pH ≤ 6 in E. coli UTI was associated with symptomatic episodes (8/60 vs. 0/55, p = 0.04) at one-month follow-up, with a similar trend in those patients receiving fosfomycin (7/47 vs. 0/41, p = 0.09). Acidic urine pH was not associated with microbiological or clinical cure in K. pneumoniae UTI. At pH 5, the ciprofloxacin MIC90 increased from 8 to >8 mg/L in E. coli and from 4 to >8 mg/L in K. pneumoniae. At pH 5, the fosfomycin MIC90 decreased from 8 to 4 mg/L in E. coli and from 512 to 128 mg/L in K. pneumoniae. Acidic urine is not associated with the microbiological efficacy of fosfomycin and ciprofloxacin in KTRs with UTI, but it is associated with symptomatic UTI episodes at one-month follow-up in E. coli episodes.
Stability analysis and rock movement prediction of stope roof below the subsidence area

In order to analyze the stability of the roof below the subsidence area,the RMR rock mass classification and the Q system rock mass classification have been used for rock quality evaluation to calculate the rock condition,and the mechanical model of the subsidence area has been established to analyze the strained state in the roof. The results show that the roof of-127 m level is unstable enough with the mechanical condition of the collapse.The possibility of the collapse of the mined-out area in-127 m level has been verified by the calculation results of the 3D FEM numerical analysis,then the time series predicting analysis has been used for rock displacement deformation.Based on the results of predicting data,the rock movement value of-127 m level increases gradually with the accumulation of potential collapse. Therefore, supporting scheme should be formulated to control the value of rock movement and the time series prediction should be forecasted periodically to monitor the tendency of the rock movement value.
Implementation of public information disclosure policy in the house of Representatives of the Republic of Indonesia

Purpose: This study aims to identify how the implementation of the public information disclosure policy in the House of Representatives (DPR) in 2019-2021 is going and to find the right strategies to be implemented so that the DPR can become an informative public body. Research methodology: This research uses a qualitative descriptive method with a case study approach, where primary and secondary data are obtained through in-depth interviews with predetermined key informants, field observations, and literature studies relevant to the research topic. Results: The findings show that the implementation of public information disclosure policy in Parliament is still not optimal due to various obstacles in the process of documenting, classifying, managing, and serving public information that are technical, administrative, bureaucratic, and political in nature. DPR needs to start building and developing an internal big data system that is connected to real time public information management and service applications. In addition, the active role of Members and factions in the House in providing public information is also important to support the successful implementation of public information disclosure in the House.
Variability of erodibility in bedrock-floored channels produced by differential weathering

4 Introduction . 5 Methods. 12 Results . 24 Discussion . 39 Conclusion . 50 Future Work . 51 Acknowledgements . 52 References . 53
Open Access proceedings Journal of Physics: Conference series

A bond graph Input-State-Output Port-Hamiltonian formulation of memristive networks for Josephson junction circuits in state space is presented. The methodology has applications to the modeling of SQUIDs and other non-linear transducers and enables the formulation of input-output models of complex components embedded in non-linear networks.
Multiplexed Imaging Mass Cytometry Analysis in Preclinical Models of Pancreatic Cancer

Pancreatic ductal adenocarcinoma (PDAC) is one of the most lethal cancers. PDAC is characterized by a complex tumor microenvironment (TME), that plays a pivotal role in disease progression and resistance to therapy. Investigating the spatial distribution and interaction of TME cells with the tumor is the basis for understanding the mechanisms underlying disease progression and represents a current challenge in PDAC research. Imaging mass cytometry (IMC) is the major multiplex imaging technology for the spatial analysis of tumor heterogeneity. However, there is a dearth of reports of multiplexed IMC panels for different preclinical mouse models, including pancreatic cancer. We addressed this gap by utilizing two preclinical models of PDAC: the genetically engineered, bearing KRAS–TP53 mutations in pancreatic cells, and the orthotopic, and developed a 28–marker panel for single–cell IMC analysis to assess the abundance, distribution and phenotypes of cells involved in PDAC progression and their reciprocal functional interactions. Herein, we provide an unprecedented definition of the distribution of TME cells in PDAC and compare the diversity between transplanted and genetic disease models. The results obtained represent an important and customizable tool for unraveling the complexities of PDAC and deciphering the mechanisms behind therapy resistance.
THE CLIMATE OF NIWOT RIDGE, FRONT RANGE, COLORADO, U.S.A.

The climate of Niwot Ridge is described using monthly and annual mean temperatures and monthly and annual total precipitation values for the period 1951 to 1985 and comparable precipitation values for the nearby Silver Lake station from 1915. Summary statistics and water budget values are presented. Time series analysis indicates abnormally low temperatures in the early 1980s and an overall downward trend in temperature. Autoregressive moving average forecasting models and spectral analysis hint at some cyclicity in the data series of annual values of both temperature and precipitation. Silver Lake annual precipitation data show only a slight downward trend when the extremely high value for the year of 1921 is excluded. Implications of these changes for the alpine tundra ecosystem are briefly discussed.
Biotechnology and Bioengineering

Funding information Puridify (now part of GE healthcare), Grant/ Award Number: EP/N013395/1; Engineering and Physical Sciences Research Council, Grant/Award Number: EP/L01520X/1 Abstract Viral vectors such as adenovirus have successful applications in vaccines and gene therapy but the manufacture of the high‐quality virus remains a challenge. It is desirable to use the adsorption‐based chromatographic separations that so effectively underpin the therapeutic protein manufacture. However fundamental differences in the size and stability of this class of product mean it is necessary to revisit the design of sorbent's morphology and surface chemistry. In this study, the behaviour of a cellulose nanofiber ion‐exchange sorbent derivatised with quaternary amine ligands at defined densities is characterised to address this. This material was selected as it has a large accessible surface area for viral particles and rapid process times. Initially, the impact of surface chemistry on infective product recovery using low (440 μmol/g), medium (750 μmol/g), and high (1029 μmol/g) ligand densities is studied. At higher densities product stability is reduced, this effect increased with prolonged adsorption durations of 24min with just ~10% loss at low ligand density versus ~50% at high. This could be mitigated by using a high flow rate to reduce the cycle time to ~1min. Next, the impact of ligand density on the separation's resolution was evaluated. Key to understanding virus quality is the virus particle: infectious virus particle ratio. It was found this parameter could be manipulated using ligand density and elution strategy. Together this provides a basis for viral vector separations that allows for their typically low titres and labile nature by using high liquid velocity to minimise both load and on‐column times while separating key product and process‐related impurities.
Consuming Mobility: A Practice Approach to Sustainable Mobility Transitions

The current fossil fuel-based system of mobility is associated with a wide range of environmental and social problems. There is a growing body of literature on system innovations and transitions which has as a common understanding that long-term transformative change is necessary to deal with these complex problems. However, knowledge on the crucial role of citizen-consumers in sustainable mobility transitions is still underdeveloped. By incorporating the viewpoint of consumption patterns and everyday life routines, this book provides (new) knowledge on the role of citizen-consumers in sustainable mobility transitions. Theoretically, a practice based approach is developed as a novel framework to analyse, understand and influence transition processes to sustainable mobility at the level of everyday life. The focus in each of the three cases studies is on situated interactions between consumers and producers. Amongst these is an analysis of the role environmental information and subsidies in new car purchasing. Also, various examples in which an attempt was made to orchestrate a (modal) shift in commuting practices are examined. Each of the empirical case studies shows the important role of contextual factors in understanding and influencing mobility behaviour of citizen-consumers. In addition, this book helps to understand how and why innovation in mobility practices takes place or not.
SnS₂ and ZnO Nanocomposite Prepared by Dispersion Method for Photodetector Application

This letter reports a SnS2 and ZnO nanocomposite (NC) prepared by dispersion method. The nanocomposite shows promising characteristics for optoelectronic application. SnS2:ZnO NC shows a wide absorption spectrum covering ultraviolet (UV)-visible-near infrared (NIR) regions. Hence, using the proposed nanocomposite a broadband photodetector with a structure comprising Al/ SnS2:ZnO/PEDOT:PSS/ Indium Tin Oxide (ITO) is fabricated. At a bias voltage of 1 V, the measured responsivity values (A/W) of the proposed device are 140.41, 848.63, and 1094.48 at 350 nm (UV), 750 nm (visible) and 900 nm (NIR), respectively.
RETRACTED ARTICLE: Field evidence of Gorkha earthquake of 25 April (7.8 M) and Kodari earthquake of 12 May 2015 (7.2 M) in Nepal

ABSTRACT25 April 2015 Gorkha Earthquake (Mw 7.8) and 12 May 2015 Kodari Earthquake (Mw 7.3) have been considered as devastating earthquakes with a heavy toll of lives and loss of properties. The present study envisages the visit of the various damaged sites affected by the recent earthquakes. The existing attenuation relationship from various existing models fails to explain the observed ground motion parameters. The Gorkha earthquake occurred as the result of thrust faulting near the Main Frontal Fault and Kodari earthquake occurred due to thrust faulting near the decollement associated with the Main Himalayan Thrust, which defines the interface between the underthrusting Indian and the overriding Eurasian Plates. The Kodari earthquake is located beyond the eastern end of that of Gorkha earthquake, but, it is not considered as aftershocks. These earthquakes caused considerable damage to life and properties and induced many mass movements in mountainous areas, which could be another cause of secondary dis.
Multi-Objective Reconfigurable Three-Phase Off-Board Charger for EV

This paper deals with the control and implementation of solar photovoltaic (PV) array-based multi-objective bi-directional charger beneficial for electric vehicle (EV), household load, and utility. For EV, the charger provides the charging facility. For household load, the charger acts as a standalone inverter, and for utility the charger acts as an active power filter. However, for providing the multi-functionality and the multi-mode operation capability of the charger, a reconfigurable control strategy is proposed. Moreover, an adaptive dc-link voltage strategy is proposed for achieving the optimum voltage at dc link under all voltage conditions for achieving minimum ripple in grid currents. The charger also uses a voltage synchronization strategy for achieving the seamless mode transition between the grid-connected and standalone modes. In grid-connected mode, the charger uses a double second-order generalized integrator-based positive sequence estimator along with the improved linear sinusoidal tracer-based algorithm for generating the balanced and sinusoidal reference grid currents, under the unbalanced and distorted grid voltages. The charger is implemented in the laboratory, and the performance is presented under various steady-state and dynamic conditions.