Miracle-dz/UniFAR-FTUs huggingface dataset:
Optimal Design of Broadband Wireless Mesh Networks

Design/planning of WMNs is the key phase before any deployment. Few proposals can be found in the open literature that deal with the design problem; moreover, they do not take into account all the parameters that have an impact on the outcome of the design and they assume the existence of a physical topology where the location and the characteristics of nodes (e.g., number of channels, number of radios) are fixed. In this paper, we define a generalized model for the WMNs design problem that takes into account all the parameters that have a significant impact on the network (interference, multi-channel, transmission power, etc.), the requirements of providers (expected amount of traffic/users), the constraints of the physical environment (potential locations of wireless routers, e.g., poles, and gateways, e.g., data centers), etc. The objective is to minimize the cost of the network and its operations while satisfying the requirements. The proposed model is shown to outperform considerably existing solutions.
Representing and encoding plant architecture: A review

A plant is made up of components of various types and shapes. The geometrical and topological organisation of these components defines the plant architecture. Before the early 1970's, botanical drawings were the only means to represent plant architecture. In the past two decades, high-performance computers have become available for plant growth analysis and simulation, triggering the development of various formal representations and notations of plant architecture (strings of characters, axial trees, tree graphs, multiscale graphs, linked lists of records, object-oriented representations, matrices, fractals, sets of digitised points, etc.). In this paper, we review the main representations of plant architecture and make explicit their common structure and discrepancies. The apparent heterogeneity of these representations makes it difficult to collect plant architecture information in a generic format to allow multiple uses. However, the collection of plant architecture data is an increasingly important issue, which is also particularly time-consuming. At the end of this review, we suggest that a task of primary importance for the plant-modelling community is to define common data formats and tools in order to create standard plant architecture database systems that may be shared by research teams.
Intracranial dural arteriovenous fistulas with or without cerebral sinus thrombosis: analysis of 69 patients

Objectives: To compare the characteristics of dural arteriovenous fistulas (AVFs) with or without cerebral sinus thrombosis (CST), and to analyse the determinants of aggressive manifestations in patients with dural AVF. Methods: We investigated 69 patients aged 51.4 (SD 15) years who were diagnosed as having dural AVF. According to the location of the lesion and venous drainage pattern, dural AVF was classified into three sites (cavernous sinus, large sinus, and other) and five types (by Cognard’s method). Aggressive manifestations of dural AVF were defined as intracranial haemorrhage, venous infarction, seizure, altered mental status, and intracranial hypertension. The diagnosis of CST was based on cerebral angiography. Logistic regression methods were used to analyse the determinants of aggressive manifestation in patients with dural AVF. Results: CST was found in 39% of the patients with dural AVF. It was located at almost either the sinus around the dural AVF or the downstream venous flow pathways of the dural AVF. There was no significant difference with regard to sex, location, or type of dural AVF between patients with dural AVF with and without CST. The location “other sinuses” and the type of dural AVF “IIb/IIa+b/III/IV/V” were significantly related to aggressive manifestations of dural AVF (odds ratio 19 (p = 0.001) and 5.63 (p = 0.033), respectively). Presence of CST in patients with dural AVF had an odds ratio of 4.25 (p = 0.12) for development of aggressive manifestations. Conclusions: CST affects two fifths of patients with dural AVF. The location and type of dural AVF are major determinants of aggressive manifestations in patients with dural AVF.
Targeting and activity-related dendritic modification in mammalian retinal ganglion cells

We have studied factors that influence the development of dendritic morphology in hamster retinal ganglion cells. By combining fluorescent retrograde tracing with in vitro Lucifer yellow injection into fixed retina, cells with appropriate and inappropriate visuotopic projections have been compared. In adult hamsters, cells with an aberrant ipsilateral projection from the nasal retina display a uniformly sparse dendritic morphology. However, following monocular enucleation at postnatal day 0 (P0), this population displays a significantly enhanced dendritic complexity in the adult. By contrast, removal of one eye at P6 or at P12 produces progressively less effect. These results suggest that dendritic complement of the adult aberrant projection can be regulated by altering the early postnatal axonal environment. The development of aberrant ganglion cells was investigated to determine the relative influences of cell death and dendritic remodeling in shaping the composition of the adult aberrant population. Aberrant cells were found to be indistinguishable from other cells in nasal retina throughout early development. After ganglion cell death (P1-P12) is over, aberrant cells still display a full range of cell types. However, at eye opening (P16) they undergo a rapid loss of dendritic complexity by remodeling. By P22, aberrant cells display a uniformly sparse dendritic morphology. When hamsters were raised in the dark between P12 (the end of ganglion cell death) and P22, this severe remodeling was blocked. This block was maintained when hamsters were dark reared to P42. Hence, both dark rearing and monocular enucleation at P0 produce similar effects on the development of visuotopically inappropriate hamster retinal ganglion cells. We speculate that the patterns of dendritic sculpting that we have observed reflect activity- mediated modulation of dendritic form via retrograde signals from the terminal arbors. This has implications for retinal ganglion cell morphological classification and, more generally, for mechanisms that influence the dendritic development of other neurons in the CNS.
Hemşirelik Öğrencilerinin Yeme Tutumları Ve Obsesif-Kompulsif Belirtileri

Objective: This study was carried out to evaluate eating attitudes and obsessive-compulsive symptoms of nursing students. Method: This study was performed with 270 nursing students between FebruaryMarch 2013, in a foundation university and a state univesity. Analyses of datas, which were collected using social-demographics questionnaire form, Maudsley Obssesive-Compulsive Question Form and Eating Attitudes Test, were performed with parametric and non-parametric tests. Results: Mean age of participants was 20.89±1.54, 88.1% were women, 33.7% were student in third class, 32.2% were student in second class and 67.8% were having education in state university. Mean body mass index was 21.48±3.12 and according to weights 75.9% were normal, 12.2% were obese, 11.9%were weak. Mean score for EAT was 15.66±8.50 and %5.6 of students have eating disorder. Mean score for MOCQ was 15.46±5.65. It was noted that eating attitudes and obssesive-compulsive signs were not effected by sex, school of education, residence and parents educational status (p>0.05). EAT scores of obese and over weighted students were significantly higher than normal weighted students (p=0.049). There was a significant difference between class of education and total MOCQ score (p=0.004), controlling (p=0.005) and slowness (p=0.009) sub-dimensions. There was a negative correlation between total MOCQ score and income (p=0.009) and age (p=0.001). In addition, very weakly positive correlations between EAT scores and total MOCQ scores (p=0.001), controlling (p=0.005), slowness (p=0.009), rumination (p=0.001) sub-dimesions were noted. Conclusion: Obesity is related with eating attitude, obsessivecompulsive signs were effeted by educating class, age and family income. An increase was noted in frequency of obsessive-compulsive signs along with eating attitude disorders
A software engineering perspective on algorithmics

An algorithm component is an implementation of an algorithm which is not intended to be a stand-alone module, but to perform a specific task within a large software package or even within several distinct software packages. Therefore, the design of algorithm components must also incorporate software-engineering aspects. A key design goal is adaptability. This goal is important for maintenance throughout a project, prototypical development, and reuse in new, unforseen contexts. From a theoretical viewpoint most algorithms apply to a range of possible use scenarios. Ideally, each algorithm is implemented by one algorithm component, which is easily, safely, and efficiently adaptable to all of these contexts. Various techniques have been developed for the design and implementation of algorithm components. However, a common basis for systematic, detailed evaluations and comparisons in view of the real practical needs is still missing. Basically, this means a set of concrete criteria, which specify what sort of adaptability is really required in practice, and which are well-justified by convincing, representative use scenarios. This paper is intended to be a first “milestone” on the way towards such a system of criteria. We will present a set of concrete goals, which are general and problem-independent and might appear ubiquitously in the algorithmic realm. These goals are illustrated, motivated, and justified by an extensive requirements analysis for a particular algorithm from a particular algorithmic domain: Dijkstra's algorithm for shortest paths in networks. Clearly, the field of algorithmics might be too versatile to allow a comprehensive, yet concise set of precise, justified criteria. Even a domain as restricted as graph and network algorithms includes aspects that are not fully understood. The analysis will include a discussion of the limits of the case study and the scope of the goals. The case study was chosen because it seems to be close to the “boderline” between the aspects that are well understood and the aspects that are not. Hence, this example may well serve as an“acid test” for programming techniques in view of the state of the art.
Evidence for preservation of cortical bone mineral density in patients on continuous ambulatory peritoneal dialysis

It is still unclear whether dialysis modality, i.e., continuous ambulatory peritoneal dialysis (CAPD) versus hemodialysis (HD) specifically affects bone mineral density (BMD). To answer this question, 34 patients on HD and 25 on CAPD were matched for age, sex, height, and body weight with 125 normal subjects. BMD was measured using dual‐energy X‐ray absorptiometry (DXA; Hologic QDR 1000/W) at the lumbar spine (trabecular bone), the femoral neck (mixed cortical and trabecular bone), the distal tibial diaphysis (cortical bone), and the epiphysis (trabecular bone) in all subjects. No significant difference for blood hemoglobin, albumin, total and ionized calcium, intact parathyroid hormone (PTH) or phosphorus concentrations, as well as for alkaline phosphatase activity, failed renal allograft, prior steroid therapy, prior parathyroidectomy, duration of uremia, or of dialysis was found between patients on HD and those on CAPD. However, the residual daily urine volume and renal function at the time of the absorptiometry were higher in CAPD than in HD patients (p < 0.05) as well as the mean dialysate calcium concentration during dialysis, the blood bicarbonate concentration, and the residual renal function at the initiation of dialysis (p, 0.01, p < 0.05, and p < 0.005, respectively). In contrast, the total dose of calcium carbonate was lower in CAPD than in HD patients (p < 0.01). Results of BMD were expressed as Z scores (the number of standard deviations from the appropriate mean of BMD of 623 healthy subjects adjusted for age and sex). At the lumbar spine, no significant difference with respect to BMD was observed between the three groups. At the femoral neck and tibial epiphysis, HD patients had lower BMD (p < 0.001) than normal controls, whereas no difference was observed between HD and CAPD patients. At tibial diaphysis, patients on HD had lower BMD (p < 0.001) than patients on CAPD and than normal controls, with the values being similar in patients on CAPD and in normal controls. The results remained identical after exact matching of HD (n = 25) and CAPD (n = 25) patients for dialysis duration (1.9 ± 03 and 1.7 ± 03 years, respectively). Multiple regression analysis revealed significant negative correlations between Z scores at the lumbar spine (p < 0.05), femoral neck (p < 0.02), tibial diaphysis (p < 0.005), and tibial epiphysis (p < 0,05) on the one hand and plasma alkaline phosphatase activity on the other. The Z score at tibial diaphysis was also correlated with residual renal function at the initiation of dialysis (p < 0.05). In conclusion, this study provides evidence for the preservation of cortical bone with CAPD as opposed to HD. The higher residual renal function observed in the former treatment modality might account, at least in part, for this finding.
Inducing Information Extraction Systems for New Languages via Cross-language Projection

Information extraction (IE) systems are costly to build because they require development texts, parsing tools, and specialized dictionaries for each application domain and each natural language that needs to be processed. We present a novel method for rapidly creating IE systems for new languages by exploiting existing IE systems via cross-language projection. Given an IE system for a source language (e.g., English), we can transfer its annotations to corresponding texts in a target language (e.g., French) and learn information extraction rules for the new language automatically. In this paper, we explore several ways of realizing both the transfer and learning processes using off-the-shelf machine translation systems, induced word alignment, attribute projection, and transformation-based learning. We present a variety of experiments that show how an English IE system for a plane crash domain can be leveraged to automatically create a French IE system for the same domain.
Zika virus in the Americas: Early epidemiological and genetic findings

Zika virus genomes from Brazil The Zika virus outbreak is a major cause for concern in Brazil, where it has been linked with increased reports of otherwise rare birth defects and neuropathology. In a phylogenetic analysis, Faria et al. infer a single introduction of Zika to the Americas and estimated the introduction date to be about May to December 2013—some 12 months earlier than the virus was reported. This timing correlates with major events in the Brazilian cultural calendar associated with increased traveler numbers from areas where Zika virus has been circulating. A correlation was also observed between incidences of microcephaly and week 17 of pregnancy. Science, this issue p. 345 Virus sequencing indicates that Zika arrived in Brazil during the middle of 2013, coincident with a surge in air travelers. Brazil has experienced an unprecedented epidemic of Zika virus (ZIKV), with ~30,000 cases reported to date. ZIKV was first detected in Brazil in May 2015, and cases of microcephaly potentially associated with ZIKV infection were identified in November 2015. We performed next-generation sequencing to generate seven Brazilian ZIKV genomes sampled from four self-limited cases, one blood donor, one fatal adult case, and one newborn with microcephaly and congenital malformations. Results of phylogenetic and molecular clock analyses show a single introduction of ZIKV into the Americas, which we estimated to have occurred between May and December 2013, more than 12 months before the detection of ZIKV in Brazil. The estimated date of origin coincides with an increase in air passengers to Brazil from ZIKV-endemic areas, as well as with reported outbreaks in the Pacific Islands. ZIKV genomes from Brazil are phylogenetically interspersed with those from other South American and Caribbean countries. Mapping mutations onto existing structural models revealed the context of viral amino acid changes present in the outbreak lineage; however, no shared amino acid changes were found among the three currently available virus genomes from microcephaly cases. Municipality-level incidence data indicate that reports of suspected microcephaly in Brazil best correlate with ZIKV incidence around week 17 of pregnancy, although this correlation does not demonstrate causation. Our genetic description and analysis of ZIKV isolates in Brazil provide a baseline for future studies of the evolution and molecular epidemiology of this emerging virus in the Americas.
Diagnostic Performance of High-Sensitivity Troponin T, Myeloperoxidase, and Pregnancy-Associated Plasma Protein A Assays for Triage of Patients with Acute Myocardial Infarction

Background Early diagnosis is the cornerstone of management of acute myocardial infarction (AMI). We aimed to compare the diagnostic accuracy of high-sensitivity troponin T (hs-cTnT) with myeloperoxidase (MPO) and pregnancy-associated plasma protein A (PAPP-A) for early diagnosis of AMI in patients at the time of presentation to the emergency department (ED). Methods We enrolled 289 patients who presented at the ED of the National Institute of Heart Disease (NIHD) Rawalpindi, Pakistan, within 4 hr of onset of chest pain. Clinical assessment, electrocardiography (ECG), and angiography were carried out. Blood samples were collected at 0, 3, 6, and 12 hr. Analyses of plasma hs-cTnT, MPO, and PAPP-A were carried out using commercial kits. Results Out of 289 subjects who presented to the ED, we diagnosed 180 patients with coronary heart disease as having AMI (N= 61) and 119 as without AMI (stable coronary artery disease, N=61; unstable angina, N=58). Compared to non-AMI patients, the patients with AMI had significantly higher levels (represented here as median [inter quartile range]) of plasma hs-cTnT (136 [39-370] vs. 12 [7-21] ng/L), MPO (906 [564-1,631] vs. 786 [351-1,299] pmol/L) and PAPP-A (5.78 [2.67-13.4] vs. 2.8 [1.8-4.9] mIU/L). Receiver operator characteristic curves (95% CI) for hs-cTnT (0.952 [0.909-0.978]) were significantly higher (P<0.001) than those for MPO (0.886 [0.830-0.929]) and PAPP-A (0.797 [0.730-0.854]), with AMI sensitivity and specificity percentages of 87% and 98% (hs-cTnT), 82% and 84% (MPO), and 65% and 87% (PAPP-A), respectively. Conclusions The diagnostic performance of hs-cTnT was superior to that of MPO and PAPP-A for early triage and diagnosis of AMI among patients of coronary heart disease presenting with chest pain to the ED.
The PtdIns3P-binding protein Phafin2 escorts macropinosomes through the cortical actin cytoskeleton

Uptake of large volumes of extracellular fluid by actin-dependent macropinocytosis plays important roles in infection, immunity and cancer development. A key question is how large macropinosomes are able to squeeze through the dense actin network underlying the plasma membrane in order to move towards the cell centre for maturation. Here we show that, immediately after macropinosomes have been sealed off from the plasma membrane, the PH-and FYVE domain-containing protein Phafin2 is recruited by a mechanism that involves binding to phosphatidylinositol 3-phosphate (PtdIns3P) generated in a non-canonical manner. Phafin2 in turn regulates the actin cross-linking protein Filamin A to promote entry of macropinosomes through the subcortical actin matrix and subsequent maturation. Depletion of Phafin2 inhibits macropinocytic internalization and maturation. We conclude that PtdIns3P and its effector Phafin2 are key components of a system that allows nascent macropinosomes to navigate through the dense subcortical actin network.
Muscarinic dependence of nucleus basalis induced conditioned receptive field plasticity

Receptive field (RF) plasticity in primary auditory cortex of adult animals, specifically selective increased response to a tonal conditioned stimulus (CS) relative to other frequencies, can be induced both by behavioral conditioning and by pairing a tone with stimulation of the nucleus basalis (NB). This study determined whether cortical muscarinic receptors are necessary for NB-induced RF plasticity. Single units in layers II–IV were studied in Urethane anesthetized adult rats. The cortex was perfused with saline or saline + atropine sulfate. Conditioning, 30 trials of pairing a tone with NB stimulation, produced a significant CS-specific response increase (n = 8). Local atropine blocked NB-induced RF plasticity, actually resulting in CS-specific response decrease (n = 6). Therefore, NB-induced RF plasticity requires engagement of muscarinic receptors in auditory cortex.
C 2015 Fangzhou Yao Secure Framework for Virtualized Systems with Data Confidentiality Protection

Benefits have been claimed by adopting virtualization techniques in many fields. It could significantly reduce the cost of managing systems, including critical systems used in cyber power grid. However, in such environments, multiple virtual instances run on the same physical machine concurrently, and reliance on logical isolation makes a system vulnerable to attacks. Virtual Machine Introspection techniques show effectiveness in building a more secure virtualized environment, since they simplify the process to acquire evidence for further analysis in this complex system. However, the VMI technique breaks down the borders of the segregation between multiple tenants, which might lead to the disclosure of cloud tenants’ data. This potential threat becomes a concern for virtual instances running critical systems, and hence it should be avoided in a public cloud computing environment. The disclosure of data could happen easily due to compromised connections, both inside and outside of the cloud, and the misuse of the cloud administrator’s authorization. Thus, in this thesis, we focus on building a secure framework, CryptVMI, to address the above concerns. Our approach maintains a client application on the user end to send queries to the cloud, as well as parse the results returned in a standard form. We also have a handler that cooperates with the introspection applications in the cloud infrastructure to process queries and return encrypted results. The introspection application is able to extract information reflecting the behaviors of the guest systems. It also demonstrates its ability to restore processes upon unexpected modification from the remote user. This work shows our design and implementation of this system, and the benchmark results prove that it does not incur much performance overhead.
Parametric structural modeling of insect wings

Insects produce thrust and lift forces via coupled fluid–structure interactions that bend and twist their compliant wings during flapping cycles. Insight into this fluid–structure interaction is achieved with numerical modeling techniques such as coupled finite element analysis and computational fluid dynamics, but these methods require accurate and validated structural models of insect wings. Structural models of insect wings depend principally on the shape, dimensions and material properties of the veins and membrane cells. This paper describes a method for parametric modeling of wing geometry using digital images and demonstrates the use of the geometric models in constructing three-dimensional finite element (FE) models and simple reduced-order models. The FE models are more complete and accurate than previously reported models since they accurately represent the topology of the vein network, as well as the shape and dimensions of the veins and membrane cells. The methods are demonstrated by developing a parametric structural model of a cicada forewing.