Miracle-dz/UniFAR-FTUs huggingface dataset:
THE UTILIZATION OF A PRESUMABLY LOW-CARIOGENIC CARBOHYDRATE DERIVATIVE.

The digestion and absorption of a presumably low-cariogenic carbohydrate derivative, a hydrogenated partial hydrolyzate of starch, has been studied. This contains free sorbitol, plus disaccharides, oligosaccharides and dextrins in which the glucose molecule which had a free aldehyde group prior to hydrogenation has been reduced to sorbitol. The dextrins present are rapidly hydrolyzed by α-amylase under the formation of di-and oligosaccharides. Those disaccharides which are composed only of glucose, are completely hydrolyzed by the intestinal disaccharidases and rapidly utilized in the body. The disaccharides containing one molecule of glucose and one of sorbitol, either initially present as disaccharide or formed on the enzymatic cleavage of the dextrins and oligosaccharides, are very slowly hydrolyzed. The glucose bound in this way largely escapes absorption. The sorbitol, whether free or bound, is very slowly absorbed.
Identification of NIPBL, a new ETV6 partner gene in t(5;12) (p13;p13)-associated acute megakaryoblastic leukemia

1 Laboratoire d ’ Histologie, Embryologie et Cytog e n e tique, Facult e de M e decine et des Sciences de la Sant e , Universit e de Bretagne Occidentale, Brest, France, 2 Institut National de la Sant e et de la Recherche M e dicale (INSERM) U1078, Brest, France, 3 Divisi o n de Gen e tica, Centro de Investigaci o n Biom e dica de Occidente, IMSS, Guadalajara, Jalisco, M e xico, 4 Departamento de Hematolog i a, UMAE-H Pediatr i a, Centro M e dico Nacional de Occidente, IMSS, Guadalajara, Jalisco, M e xico, 5 Unidad de Biolog i a Molecular, Gen o mica y Secuenciaci o n, Centro de Investigaci o n y Desarrollo en Ciencias de la Salud, Universidad Aut o noma de Nuevo Le o n, Monterrey, Nuevo Le o n, Mexico and 6 Service de Cytog e n e tique, Cytologie et Biologie de la Reproduction, H o pital Morvan, CHRU Brest, Brest, France
SIEM: An Integrated Evaluation Metric for Measuring Search Engine's Performance

engines as Web-based information retrieval applications traverse a database consisting of millions of Web documents upon receiving a user issued query. In order to evaluate the accuracy and strength of a search engine regarding its robustness in finding relevant Web documents, a set of metrics have been proposed by researchers that each of them evaluates one aspect of a search engine's performance. One of the existing challenges in this area is the lack of one measurement that could state a search engines performance from different perspectives. Some of developed metrics so far are general information retrieval evaluation measures that are not designed as specialized tools for search engine's evaluation. Some other metrics measure the system ability in finding accurate data while other metrics measures the speed of the system for performing the search process. In this paper different evaluation metrics such as precision, recall, f-measure, MAP, MRR, DCG and NDCG will be discussed. Then according to the conducted experiment and an analytical solution, a hybrid evaluation metric is proposed that based on it the overall strength of a search engine could be measured.
Optic nerve dysplasia and renal insufficiency in a family with a novel PAX2 mutation, Arg115X: further ophthalmologic delineation of the renal-coloboma syndrome

Renal-coloboma syndrome, an autosomal dominant disorder associated with mutations in PAX2 , is characterized by colobomatous eye defects, renal hypoplasia, vesicoureteral reflux, high-frequency hearing loss, and rarely central nervous system abnormalities. We identified a three-generation family with optic nerve colobomatous dysplasia and renal disease. We report the identification of a novel mutation in PAX2 in this family with renal-coloboma syndrome, Arg115X. We also report on the ocular and extraocular manifestations of PAX2 mutations for all cases of renal-coloboma syndrome reported to date.
A Java reuse repository for Eclipse using LSI

Software reuse is a concept that is frequently mentioned as a way to improve software developers' productivity. However, there are a number of issues that need to be addressed in order for software reuse to be adopted by developers. One of those issues is providing enough reusable artifacts. The Java Standard API has been quite successful in this, with the latest version having over 3000 classes available. However this raises the issue of finding the right artifact to reuse. With the Java API, this means trawling through the JavaDoc Web pages, which has the risk of not being able to find the right artifact, even though it is in the API. In this paper, we explore the use of latent semantic indexing as a means to index the Java API JavaDoc pages. Specifically, we describe Prophecy, an Eclipse plug-in that presents the Java API as a software repository
Dynamic control of 3-D rolling contacts in two-arm manipulation

When two or more arms are used to manipulate a large object, it is necessary to maintain and control contacts between the object and effector(s) on one or more arms. The dynamic control of two arms manipulating a large object with rolling contacts is addressed. In the framework presented, the motion of the object as well as the loci of the contact points on the surface of the effectors and on the object can be directly controlled. The velocity and acceleration equations for three-dimensional rolling contacts are derived in order to obtain a dynamical model of the system. A nonlinear feedback algorithm that decouples and linearizes the system is used to demonstrate the control of rolling motion along each arm and the adaption of grasps to varying loads. <<ETX>>
An Approach to Evaluate Blurriness in Retinal Images with Vitreous Opacity for Cataract Diagnosis

Cataract is one of the leading causes of blindness in the world's population. A method to evaluate blurriness for cataract diagnosis in retinal images with vitreous opacity is proposed in this paper. Three types of features are extracted, which include pixel number of visible structures, mean contrast between vessels and background, and local standard deviation. To avoid the wrong detection of vitreous opacity as retinal structures, a morphological method is proposed to detect and remove such lesions from retinal visible structure segmentation. Based on the extracted features, a decision tree is trained to classify retinal images into five grades of blurriness. The proposed approach was tested using 1355 clinical retinal images, and the accuracies of two-class classification and five-grade grading compared with that of manual grading are 92.8% and 81.1%, respectively. The kappa value between automatic grading and manual grading is 0.74 in five-grade grading, in which both variance and P value are less than 0.001. Experimental results show that the grading difference between automatic grading and manual grading is all within 1 grade, which is much improvement compared with that of other available methods. The proposed grading method provides a universal measure of cataract severity and can facilitate the decision of cataract surgery.
Carbon in urban, brownfield and heavy metal contaminated soils

This thesis is comprised of a collection of work on urban, brownfield and heavy metal contaminated soils carried out within the North West of England from March 2007 to December 2009. Field and laboratory based experiments were used to determine the amount of carbon stored in urban soils and fluxes of dissolved organic carbon and soil respiration. The effects of added organic amendments on carbon storage and mobility as well as the onward implications to heavy metals and arsenic mobility and the impact of earthworms on these processes were also investigated. A city-wide topsoil survey of parkland and road verges in Liverpool showed that carbon storage ranged from 10 kg total organic carbon m-2 whilst physico-chemical characteristics and heavy metal and arsenic concentrations also varied considerably. The abundance oftechnogenic material restricted organic carbon storage and flux to the upper 30 cm of an inner city lawn soil studied in greater detail. Brownfield soil carbon storage and fluxes were enhanced by adding a small amount of green waste compost to these soils but large applications did not greatly increase carbon storage further. Enhanced losses of carbon by dissolved organic carbon leaching and increased soil respiration rates were consequences of greenwaste compost additions, although these effects were highly seasonal, occurring in greatest magnitude at the warmest periods of the year. Proportionately, the annual losses of carbon to soil respiration were far greater than those to dissolved organic carbon. An amendment consisting predominantly of woody material and a biochar amendment had a lower impact than composted greenwaste on dissolved organic carbon mobility, and the co-mobilisation of heavy metals and arsenic in a soil from a previously heavily industrialised centre of population. Earthworms reduced dissolved organic carbon when inoculated with compost and biochar amended soil, but increased this soluble fraction of carbon in woody amended soils, with attendant consequence to trace metal and arsenic mobility. Zinc and cadmium mobility were largely independent of changes in soluble carbon, but arsenic, copper and lead were heavily influenced by added carbon. Biochar amendment proved very effective in reducing concentrations of soluble cadmium and zinc in a heavy metal contaminated soil by adsorption, as well as having the added benefit of reducing total and bioavailable polycyclic aromatic hydrocarbon (PAH) concentrations. It is concluded that carbon storage in urban soils can potentially be increased by applying organic amendments, although longer-term carbon storage may only be substantially enhanced with repeated applications of amendments. However, in urban soils with significant residual pollution, it can be questioned whether this practice is environmentally sound, regarding mobilisation of potentially harmful trace elements. Biochar and larger woody fraction amendments to soils may be more efficacious.
Regenerative nodules in liver cirrhosis: findings at CT during arterial portography and CT hepatic arteriography with histopathologic correlation.

PURPOSE To determine the appearance of regenerative nodules in patients with liver cirrhosis at computed tomography (CT) during arterial portography (CTAP) and CT hepatic arteriography (CTHA). MATERIALS AND METHODS CTAP and CTHA of the liver were performed in 28 consecutive patients with hepatocellular carcinoma (HCC) who were scheduled to undergo partial resection of the liver. Helical CTAP was performed after contrast material injection into the superior mesenteric artery followed by helical CTHA after contrast material injection into the hepatic artery. CT scans were analyzed for the presence of identifiable nodules and their size; results were correlated with gross and microscopic findings. RESULTS Resected livers showed cirrhosis in 20 patients, chronic hepatitis in four, and normal liver in four. Among the 20 patients with cirrhosis, regenerative nodules were demonstrated as enhancing 3-10 mm nodules surrounded by lower attenuation fibrous septa 0.8-1.5 mm thick at CTAP in seven patients and nonenhancing nodules of the same size surrounded by enhancing fibrous septa at CTHA in 15 patients. The degree of fibrosis determined the conspicuity of nodules. CONCLUSION Regenerative nodules in cirrhotic liver are visualized as enhancing nodules surrounded by lower attenuation thin septa at CTAP and nonenhancing nodules surrounded by enhancing fibrous septa at CTHA. CTHA is more sensitive than CTAP in depicting regenerative nodules (P < .005).
A method for characterization of coherent backgrounds in real time and its application in gravitational wave data analysis

Many experiments, and in particular gravitational wave detectors, produce continuous streams of data whose frequency representations contain discrete, relatively narrowband coherent features at high amplitude. We discuss the application of digital Fourier transforms (DFTs) to characterization of these features, hereafter frequently referred to as lines. Application of DFTs to continuously produced time-domain data is achieved through an algorithm [7], hereafter referred to as EFCEvolving Fourier coefficient. , for efficient time-domain determination of the Fourier coefficients of a data set. We first define EFC and discuss parameters relating to the algorithm that determine its properties and action on the data. In gravitational wave interferometers, these lines are commonly due to parasitic sources of coherent background interference coupling into the instrument. Using GEO 600 data, we next demonstrate that time-domain subtraction of lines can proceed without detrimental effects either on features at frequencies separated from that of the subtracted line, or on features at the frequency of the line but having different stationarity properties.
Dark Energy Constraints from Baryon Acoustic Oscillations

Baryon acoustic oscillations (BAOs) in the galaxy power spectrum allow us to extract the scale of the comoving sound horizon at recombination, a cosmological standard ruler accurately determined by the cosmic microwave background anisotropy data. We examine various issues important in the use of BAOs to probe dark energy. We find that if we assume a flat universe and priors on Ωm, Ωmh2, and Ωbh2 as expected from the Planck mission, the constraints on dark energy parameters (w0, w') scale much less steeply with survey area than (area)-1/2 for a given redshift range. The constraints on the dark energy density ρX(z), however, do scale roughly with (area)-1/2 due to the strong correlation between H(z) and Ωm (which reduces the effect of priors on Ωm). Dark energy constraints from BAOs are very sensitive to the assumed linear scale of matter clustering and the redshift accuracy of the survey. For a BAO survey with 0.5 ≤ z ≤ 2, σ (R) = 0.4 [corresponding to kmax (z = 0) = 0.086 h Mpc-1], and σz/ (1 + z) = 0.001, we find = (0.115,0.183) and (0.069, 0.104) for survey areas of 1000 and 10,000 deg2, respectively. We find that it is critical to minimize the bias in the scale estimates in order to derive reliable dark energy constraints. For a 1000 (10,000) deg2 BAO survey, a 1 σ bias in ln H (z) leads to a 2 σ (3 σ) bias in w'. The bias in w' due to the same scale bias from ln DA (z) is slightly smaller and opposite in sign. The results from this paper will be useful in assessing different proposed BAO surveys and guiding the design of optimal dark energy detection strategies.
Winding quotients and some variants of Fermat's Last Theorem.

giving an abundant but rather uninteresting supply of solutions to equation (2). It is natural to restrict ones attention to the primitive solutions, which is what we will do from now on. Equations (1), (2) and (3) also have certain obvious “trivial” solutions: a solution is called trivial if xyz = 0 or ±1, and is called non-trivial otherwise. The work of Hellegouarch, Frey [12], Serre [27], and Ribet [24] relating Fermat’s Last Theorem to the Shimura-Taniyama conjecture (and the precise
New flexible OFDM structure for consumer electronics communication systems

This paper introduces a promising property in which the transmitter of an OFDM system can utilize an N-point IFFT operation to build the time-domain symbols of a KN-point IFFT operation. Based on this property, we propose a flexible OFDM structure. This structure will support uplink applications which include many transmitters using different numbers of subcarriers and one receiver with just one IFFT/FFT module with the subcarriers of least common multiple (LCM) for the number of subcarriers of all the transmitters. Therefore it reduces the design complexities of the receiver and increases the compatible characteristics for consumer electronics (CE). Compared with the original OFDM system, the proposed system improves the performance of the packet error ratio (PER) and the bit error ratio (BER) performance by using the appropriate K. In addition, the proposed structure can be designed to enlarge the bandwidth efficiency of the system and improve the performance of channel estimation compared with the OFDM/TDM system.
Role of Positron Emission Tomography-Computed Tomography in Head and Neck Cancer

Head and neck squamous cell carcinoma (HNC) is the sixth most common cancer worldwide. In the United States, it accounts for approximately 2% of all cancers and 2% of cancer deaths. The introduction of integrated positron emission tomography and computed tomography (PET/CT) has revolutionized imaging by permitting improved and more accurate anatomic localization of functional abnormalities in the complex territory of the head and neck region, and PET/CT has become a standard clinical imaging modality in patients with HNC. The main indications for PET/CT in HNC are in pretherapy staging, detection of unknown primaries, and monitoring of therapy response or disease surveillance. Although PET/CT is a promising tool in diagnosis and surveillance of HNC, there is lack of consensus as to its use, accuracy, and implications for patient management. The existing literature on the role of PET/CT in the management of HNC is reviewed, and a summary of the current debate is provided. Second primary cancers are the main cause of death among HNC patients with early disease, and the presence of distant metastases greatly impairs the survival of patients with advanced HNC. Therefore, early detection of second primary and metastatic tumors is imperative for optimizing survival outcome. However, given the lack of randomized, prospective trials addressing the role of PET/CT after chemoradiotherapy, the ideal function of PET/CT in disease surveillance has yet to be defined.
Forest Fire Detection in Wireless Sensor Network Using Fuzzy Logic

The multi-purpose integrated homeland surveillance security systems are usually located in remote areas. Intelligent decision making (IDM) capability emerges as the primary feature in the realization of the T/R architecture. The aim of employing IDM is two-fold. First is to save energy, as the system operation is desired to be autonomous based on the available solar power and the corresponding battery-bank. Second is to activate the necessary action(s) required based on the pre-defined sensitivity levels. The current work is focused on the second aim using the pre-defined sensitivity levels. We propose to use a wireless sensor network (WSN) for data harvesting to be used as raw input data into our control system. Fire detection has been chosen to illustrate the IDM capability of the system. A Fuzzy Logic algorithm is developed using five membership functions as temperature, smoke, light, humidity and distance. Simulation results for the probability of fire based on the fuzzy rules using the status of the membership functions are presented in the paper.
Nine‐color flow cytometry for accurate measurement of T cell subsets and cytokine responses. Part I: Panel design by an empiric approach

Polychromatic flow cytometry offers the unprecedented ability to investigate multiple antigens per cell. Unfortunately, unwanted spectral overlaps and compensation problems increase when more than four colors are used, but these problems can be minimized if staining combinations are chosen carefully. We used an empiric approach to design, test and identify six‐color T cell immunophenotyping reagent panels that can be expanded to include three or more functional or other markers in the FITC, PE, and APC channels without significant spectral limitations. Thirty different six‐color T cell surface antigen reagent panels were constructed to identify major T cell subsets and maturational subtypes as defined by CCR7 and CD45RA expression, while excluding monocytes, B and non‐viable cells. Staining performance of each panel was compared on cryopreserved cells from a single healthy donor recorded on a multiparameter cell sorter. Ten of the thirty reagent panels offered reliable resolution of T cell major and maturational surface markers. Of these, two panels were selected that showed the least spectral overlap and resulting background increase in the FITC, PE, and APC channels. These channels were left unoccupied for inclusion of additional phenotypic or functional markers, such as cytokines. Careful reagent titration and testing of multiple candidate panels are necessary to ensure quality results in multiparametric measurements. © 2008 International Society for Advancement of Cytometry.
Distributing Frequency-Dependent Data Stream Computations

Data stream computations in domains such as internet applications are often performed in a highly distributed fashion in order to save time. An example is the class of applications that use the Google Mapreduce framework of scalable distributed processing as presented by (Dean & Ghemawat 2004). A basic question here is: what kind of data stream computations admit scalable and efficient distributed algorithms? We show that the class of data stream computations that approximate functions of the frequency vector of the stream can be computed efficiently in a distributed manner.
Analytical SIR for Self-Organizing Wireless Networks

The signal to interference ratio (SIR) in the presence of multipath fading, shadowing and path loss is a valuable parameter for studying the capacity of a wireless system. This paper presents a new generalized path loss equation that takes into account the large-scale path loss as well as the small-scale multipath fading. The probability density function (pdf) of the SIR for self-organising wireless networks with Nakagami- channel model is analytically derived using the new path loss equation. We chose the Nakagami- channel fading model because it encompasses a large class of fading channels. The results presented show good agreement between the analytical and Monte Carlo- based methods. Furthermore, the pdf of the signal to interference plus noise ratio (SINR) is provided as an extension to the SIR derivation. The analytical derivation of the pdf for a single interferer in this paper lays a solid foundation to calculate the statistics for multiple interferers.
Synthesis and Characterization of Novel 2-Amino-Chromene-Nitriles that Target Bcl-2 in Acute Myeloid Leukemia Cell Lines

The anti-apoptotic protein Bcl-2 is a well-known and attractive therapeutic target for cancer. In the present study the solution-phase T3P-DMSO mediated efficient synthesis of 2-amino-chromene-3-carbonitriles from alcohols, malanonitrile and phenols is reported. These novel 2-amino-chromene-3-carbonitriles showed cytotoxicity in human acute myeloid leukemia (AML) cell lines. Compound 4g was found to be the most bioactive, decreasing growth and increasing apoptosis of AML cells. Moreover, compound 4g (at a concentration of 5 µM) increased the G2/M and sub-G1 (apoptosis) phases of AML cells. The AML cells treated with compound 4g exhibited decreased levels of Bcl-2 and increased levels of caspase-9. In silico molecular interaction analysis showed that compound 4g shared a similar global binding motif with navitoclax (another small molecule that binds Bcl-2), however compound 4g occupies a smaller volume within the P2 hot spot of Bcl-2. The intermolecular π-stacking interaction, direct electrostatic interactions, and docking energy predicted for 4g in complex with Bcl-2 suggest a strong affinity of the complex, rendering 4g as a promising Bcl-2 inhibitor for evaluation as a new anticancer agent.