Miracle-dz/UniFAR-FTUs huggingface dataset:
A novel super-resolution music-based pseudo-bispectrum

The high-resolution capability of eigen-decomposition-based techniques motivates their extension to the higher-order domain. A two-dimensional version of the MUSIC algorithm for estimating the quadratic phase coupling between two frequency components in the bispectrum domain is proposed in this paper. The algorithm is based on the Singular Value Decomposition (SVD) of a toeplitz matrix derived from the third-order cumulant sequence of the process. This matrix is decomposed into two orthogonal subspaces, the signal and the noise subspaces. A frequency estimation function matching the one used in the MUSIC algorithm is then constructed using the noise singular vectors. The proposed algorithm is aimed at extracting the phase-coupled frequencies in the bispectrum. Comparable resolution to the parametric approach of bispectrum estimation based on a non-Gaussian white noise driven Auto Regressive (AR) model is achievable for the same data length and better resolution is obtained for short data segments.
RANZCP 2017 Book of Abstracts

Background: Attention-deficit hyperactivity disorder (ADHD) is one of the most common mental health disorders in children. Limitations of behavioural interventions and pharmacological treatment have led to the development of other novel interventions. Neurofeedback has shown promise in improving not only inattention symptoms but also impulsivity/hyperactivity symptoms. A feed-forward mechanism has been proposed to be more feasible in the treatment of ADHD as it trains individuals to harness their ability to pay attention and also shows promise in improving impulsivity symptoms. Objectives: The aim of the current study is to investigate the impact of a novel intervention using (feed-forward) brain-to-computer interface (BCI) technology on an objective measure of attention and impulsivity in children with ADHD. Methods: A total of 172 children aged 6 to 12 years (mean = 8.63, standard deviation = 1.51) with a clinical diagnosis of ADHD, inattentive or combined subtype were recruited. Participants were randomized into the waitlist-control or intervention group. Participants in the intervention group underwent 24 sessions of brain-to-computer interface technology (BCI) intervention over a period of 8 weeks, whereas participants in the control group did not receive any intervention. The Conners’ Continuous Performance Test, second edition (CPT-II) was administered to the participants before and after the treatment. Findings: Analysis was conducted for the intervention and control groups at weeks 1 and 8.Conclusions: Results will be discussed with a view to inform future research.
Emotional distress in Motor Neurone Disease : the role of metacognitive beliefs and repetitive negative thinking

Understanding of the factors that predict emotional distress in Motor Neurone Disease (MND) is limited. This systematic review aimed to appraise currently available data to understand the clinical and demographic, social, and psychological factors that predict distress over time. A systematic search was conducted in three online databases (Medline, PsychINFO and CINAHL Plus) up to November 2016. Studies were included if they were prospective studies assessing if clinical and demographic, psychological, or social factors at baseline predicted distress at followup at least one month later in adults with a diagnosis of MND. Only studies written in the English language, using validated measures of distress or quality of life psychological subscales were included. The methodological quality of the articles was also assessed. In total 11 studies were included. Demographic or clinical factors were investigated in all 11 studies, social factors in two studies, and psychological factors in three studies. No conclusive predictors were identified due to the limited number of studies assessing the same predictors, and null or contradictory findings. There was scarce evidence that baseline demographic factors predicted distress. For clinical factors, there was minimal evidence that percutaneous endoscopic gastrostomy use reduced distress. For social factors, there was consistent evidence that lower social support predicted increased distress. Psychological factors were considered only in individual studies, not allowing for comparison of findings. Cognitive appraisals of coping potential, mindfulness, and psychological quality of life were predictors in single studies indicating a need for further research. Findings support previous research that there is no simple or consistent relationship between physical factors and distress. Findings also highlight the lack of prospective research considering potential predictors of distress in MND. Further research is EMOTIONAL DISTRESS AND PSYCHOLOGICAL PROCESSES IN MND 8 needed to investigate the mechanisms underlying distress, particularly modifiable factors such as psychological factors, to reduce distress in people living with MND. Review Registration Number: PROSPERO ID:CRD42017050036
CO line emission from Lyman break galaxies - cosmological simulations and predictions for ALMA

Context. The detection of the rotational lines of CO in proto-galaxies in the early Universe provides one of the most promising ways of probing the fundamental physical properties of a galaxy, such as its size, dynamical mass, gas density, and temperature. While such observations are currently limited to the most luminous galaxies, the advent of ALMA will change the situation dramatically, resulting in the detection of numerous normal galaxies at high redshifts. Aims. We investigate the morphology and strength of the CO rotational line emission emerging from z ~ 3 progenitor systems of normal field galaxies seen in the present-day Universe, examine how well ALMA will be able to detect such systems and how accurately CO line widths, gas morphologies and ultimately dynamical masses can be inferred. Methods. Maps and spectra of rotational CO line emission were calculated from a cosmological N-body/hydrodynamical TreeSPH simulation of a z ~ 3 “Lyman break galaxy” of UV luminosity about one order of magnitude below L^∗. To simulate a typical observation of our system with ALMA, we imposed characteristic noise, angular, and spectral resolution constraints. Results. The CO line properties predicted by our simulation are in good agreement with the two Lyman break systems detected in CO to date. We find that while supernovae explosions from the ongoing star formation carve out large cavities in the molecular ISM, they do not generate large enough gas outflows to make a substantial imprint on the CO line profile. This implies that for most proto-galaxies – except possibly the most extreme cases – stellar feedback effects do not affect CO as a dynamical mass tracer. Conclusions. Detecting CO in sub-L^∗ galaxies at z similar or equal to 3 will push ALMA to the limits of its cababilities, and whether a source is detected or not may depend critically on its inclination angle. Both these effects (sensitivity and inclination) will severely impair the ability of ALMA to infer the gas kinematics and dynamical masses using line observations.
Mobility based application specific low power routing protocol for wireless sensor networks

Data gathering is a common but critical operation in many applications of wireless sensor networks (WSNs). Innovative techniques that improve Energy efficiency to prolong the network lifetime are highly required. The lifetime of a sensor system is the time during which it gathers information from all the sensors to the base station (BS). Given the location of sensors, BS and the available energy at each sensor, there is a requirement of an efficient manner in which the data should be collected from all the sensors and transmitted to BS, such that the system lifetime is maximized. In this paper, the researchers investigated a mobility based application specific low power routing (M-ASLPR) protocol for mobile WSNs (MWSNs). In this protocol, a sensor node gets elected as CH depending upon some parameters like residual energy, mobility and connection time etc. Simulation results show that the performance of M-ASLPR protocol is varied in terms of network lifetime according to the dynamic node densities and speed. The network lifetime gets affected on increasing the number of mobile nodes and speed which is due to high traffic in the network as mobile nodes interfere with each other.
Comparative Analysis of Team effectiveness Achievement Motivation among Badminton, Basket Ball and Foot Ball players

The purpose of this study was to find out the compare and analyse of Team effectiveness Achievement Motivation among Badminton, Basketball and Football players. To achieve the purpose of the study, 90 subjects (30 players from each game) were selected randomly as subjects. The age of the subjects ranged from 18 to 25 years. The static group comparison design was used for this Study. All the subjects responded to the questionnaire to assess the psychological variables. The collected data from the two factors, namely, game and groups were statistically analysed by using two-way (3x4) factorial Analysis of Variance (ANOVA).
PERADILAN ADAT DAN KEADILAN RESTORATIF

Pemikiran mengenai akses kepada keadilan sejatinya tidak merujuk kepada keadilan yang merujuk pada pemidanaan melainkan merujuk pada kebersaman. Dengan demikian sengketa diselesaikan melalui kesepakatan semua pihak yang terkait sehingga dapat mewujudkan perdamaian, persaudaraan dan upaya mengembalikan masyarakat kepada ketertiban dan ketenteraman sesuai dengan perasaan dan kesadaran hukum yang hidup di masyarakat yang bersangkutan. Indonesia memiliki khasanah kebudayaan berupa sistem sosial dan hukum tentang peradilan, hakim dan keadilan. Tulisan ini mengangkat permasalahan mengenai bagaimana bentuk mediasi penal dan perlindungan korban dalam restorative justice sistem; bagaimana gambaran hukum adat dan peradilannya di Indonesia; bagaimana mekanisme penyelesaian sengketa alternatif dan keadilan restoratif dalam hukum adat; serta bagaimana penanganan Pelanggaran Adat dan mediasi penal dalam hukum adat. Dengan menggunakan metode yuridis normatif dapat disimpulkan bahwa peradilan adat menjadi penting dalam kehidupan hukum nasional. Oleh karena itu dibutuhkan trasformasi nilai hukum adat yang hidup di masyarakat tentang hukum, peradilan, hakim dan keadilan, menjadi bagian perangkat sistem hukum nasional. Upaya ini penting dilakukan guna mengahiri dikotomi antar pranata dan pemikiran ”hukum negara” dan lembaga dan pranata ”hukum rakyat”. Pendekatan keadilan restoratif dalam penerapan dan penegakan hukum, merupakan jembatan teoritis dan filosofis, untuk menjadikan nilai-nilai hukum yang hidup di masyarakat, sebagai dasar legitimasi pengembangan dan berfungsinya hukum, peradilan dan hakim adat, dalam distribusi keadilan. The idea of access to justice should duly refer to the concept of harmony and not on punishment. Thereby the disputes were settled through agreement of all parties concerned in realizing peace, brotherhood and efforts to restore order and peace in accordance to the community awareness of law. Indonesia has various cultural repertoire of social and legal systems of courts, judges and justice. This paper raises the issue of how to form penal mediation and protection of victims in restorative justice system; overview on how customary law and justice in Indonesia; how alternative dispute resolution and restorative justice in customary law; as well as how to handle violations of Indigenous and penal mediation in customary law. By using normative methods can be concluded that the customary justice become important in the national law system. Therefore, it is necessary to transform the customary law values that live in the community, like the law, justice, judge, and equity, as a part of the national law system. This effort is important in order to end the dichotomy between the institutions and ideas of "state law" and "folk law". Implementation of restorative justice method is important to be the theoretical and philosophical bridge, to make the legal values that live in the community, as a basis for the development and the proper functioning of the legitimacy of customs law, justice and judges, in fairness distribution.
Generic load regulation framework for Erlang

Although Telecoms, the domain for which Erlang was conceived, has strong and ubiquitous requirements on overload protection, the Erlang/OTP platform offers no unified approach to addressing the problem. The Erlang community mailing list frequently sports discussions on how to avoid overload situations in individual components and processes, indicating that such an approach would be welcome. As Telecoms migrated from carefully regulated single-service networks towards multimedia services on top of best-effort multi-service packet data backbones, much was learned about providing end-to-end quality of service with a network of loosely coupled components, with only basic means of prioritization and flow control. This paper explores the similarity of such networks with typical Erlang-based message-passing architectures, and argues that a robust way of managing high-load conditions is to regulate at the input edges of the system, and sampling known internal choke points in order to dynamically maintain optimum throughput. A selection of typical overload conditions are discussed, and a new load regulation framework - JOBS - is presented, together with examples of how such overload conditions can be mitigated.
Positively curved manifolds with maximal discrete symmetry rank

Let M be a closed simply connected n -manifold of positive sectional curvature. We determine its homeomorphism or homotopic type if M also admits an isometric elementary p -group action of large rank. Our main results are: There exists a constant p ( n ) 0 such that (1) If M 2 n admits an effective isometric [inline-graphic xmlns:xlink="http://www.w3. org/1999/xlink" xlink:href="01i" /]-action for a prime p ≥ p ( n ), then k ≤ n and "=" implies that M 2 n is homeomorphic to a sphere or a complex projective space. (2) If M 2 n +1 admits an isometric S 1 × [inline-graphic xmlns:xlink="http://www.w3. org/1999/xlink" xlink:href="02i" /]-action for a prime p ≥ p ( n ), then k ≤ n and "=" implies that M is homeomorphic to a sphere. (3) For M in (1) or (2), if n ≥ 7 and k ≥ [3 n /4] + 2, then M is homeomorphic to a sphere or homotopic to a complex projective space.
Skin regeneration in deep second-degree scald injuries either by infusion pumping or topical application of recombinant human erythropoietin gel

Large doses of recombinant growth factors formulated in solution form directly injected into the body is usual clinical practice in treating second-degree scald injuries, with promising results, but this approach creates side effects; furthermore, it may not allow appropriate levels of the factor to be sensed by the target injured tissue/organ in the specific time frame, owing to complications arising from regeneration. In this research, two delivery methods (infusion pumping and local topical application) were applied to deliver recombinant human erythropoietin (rHuEPO) for skin regeneration. First, rHuEPO was given in deep second-degree scald injury sites in mice by infusion pump. Vascularization was remarkably higher in the rHuEPO pumping group than in controls. Second, local topical application of rHuEPO gel was given in deep second-degree scald injury sites in rats. Histological analysis showed that epithelialization rate was significantly higher in the rHuEPO gel-treated group than in controls. Immunohistochemical studies showed that the rHuEPO gel-treated group showed remarkably higher expression of skin regeneration makers than the control group. An accurate method for visualization and quantification of blood vessel networks in target areas has still not been developed up to this point, because of technical difficulties in detecting such thin blood vessels. A method which utilizes a series of steps to enhance the image, removes noise from image background, and tracks the vessels edges for vessel segmentation and quantification has been used in this study. Using image analysis methods, we were able to detect the microvascular networks of newly formed blood vessels (less than 500 μm thickness), which participate in the healing process, providing not only nutrition and oxygen to grow tissues but also necessary growth factors to grow tissue cells for complete skin regeneration. The rHuEPO-treated group showed higher expression of stem cell markers (CD 31, CD 90, CD 71, and nestin), which actively contribute to in-wound-healing processes for new hair follicle generation as well as skin regeneration. Collectively, both rHuEPO group pumping into the systemic circulation system, and injection into the local injury area, prompted mice and rats to form new blood vessel networks in scald injury sites, which significantly participate in the scald healing process. These results may lead to the development of novel treatments for scald wounds.
Distinct functions of monoclonal IgG antibody depend on antigen-site specificities

Intraveneous hyperimmunization of selectivity bred rabbits with streptococcal group A-variant vaccines elicits antibody responses of restricted heterogeneity at high antibody levels. All antisera contain two functionally distinct antibody populations, which can be isolated in single-band purity upon analytical isoelectric focusing. Typical examples of these two kinds of single-band antibodies were investigated in great detail for several parameters by a variety of methods. 85--99% of the streptococcal group A-variant polysaccharide (Av-CHO)-specific antibody in the antisera does not precipitate the isolated 5,000 daltons poly-L-rhamnose antigen, neither agglutinates nor lyses in the presence of complement Av-CHO-coated sheep erythrocytes (SRBC), binds the radio-labeled Av-CHO with an association constant in the ragne of 10(5)--10(6) M-1, and is of terminal specificity (nonreducing end) for the linear Av-CHO. In contrast, the minor fraction of Av-CHO-specific antibody (1--15%) does precipitate the linear Av-CHO, both agglutinates and lyses Av-CHO-coated SRBC in the presence of complement, has an affinity range of 10(8)--10(9) M-1, and is of internal specificity for the Av-CHO. The antigenic determinants of the Av-CHO for the antibodies are nonoverlapping, only one Fab of the low affinity antibody can be bound whereas four Fab of the high affinity antibody are accommodated. Hence, the determinant specificity explains the functional differences observed, for there is no indication of subclass differences. A mechanistic model of the A-variant carbohydrate presentation on the vaccine appears to account best for the unbalanced levels of low and high affinity antibody.
A time-respecting null model to explore the structure of growing networks

A major challenge in network science is to determine whether an observed network property reveals some non-trivial behavior of the network’s nodes, or if it is a consequence of the network’s elementary properties. Statistical null models serve this purpose by producing random networks whilst keeping chosen network’s properties ﬁxed. While there is increasing interest in networks that evolve in time, we still lack a robust time-aware framework to assess the statistical signiﬁcance of the observed structural properties of growing networks. We ﬁll this gap by introducing a null model that, diﬀerently from static models, preserves both the network’s degree sequence and the individual nodes’ degree time-series. By preserving the temporal linking patterns of the real systems it is applied to, the proposed model disentangles structural from temporal patterns. As a consequence, it allows us to properly assess the signiﬁcance of structural properties in settings where temporal patterns heavily impact the outcomes of structural measurements, which is the case for a wide range of real networks. We apply the model to real citation networks to explore the signiﬁcance of widely studied network properties such as degree-degree correlations and the relations between popular node centrality metrics. The proposed model can be used to assess the signiﬁcance of structural properties for any growing network.
Carleman Estimate for Stochastic Parabolic Equations and Inverse Stochastic Parabolic Problems

In this paper, we establish a global Carleman estimate for stochastic parabolic equations. Based on this estimate, we solve two inverse problems for stochastic parabolic equations. One is concerned with a determination problem of the history of a stochastic heat process through the observation at the final time T , for which we obtain a conditional stability estimate. The other is an inverse source problem with observation on the lateral boundary. We derive the uniqueness of the source.
Modulation, Plasticity and Pathophysiology of the Parallel Fiber-Purkinje Cell Synapse

The parallel fiber-Purkinje cell (PF-PC) synapse represents the point of maximal signal divergence in the cerebellar cortex with an estimated number of about 60 billion synaptic contacts in the rat and 100,000 billions in humans. At the same time, the Purkinje cell dendritic tree is a site of remarkable convergence of more than 100,000 parallel fiber synapses. Parallel fiber activity generates fast postsynaptic currents via α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptors, and slower signals, mediated by mGlu1 receptors, resulting in Purkinje cell depolarization accompanied by sharp calcium elevation within dendritic regions. Long-term depression (LTD) and long-term potentiation (LTP) have been widely described for the PF-PC synapse and have been proposed as mechanisms for motor learning. The mechanisms of induction for LTP and LTD involve different signaling mechanisms within the presynaptic terminal and/or at the postsynaptic site, promoting enduring modification in the neurotransmitter release and change in responsiveness to the neurotransmitter. The PF-PC synapse is finely modulated by several neurotransmitters, including serotonin, noradrenaline and acetylcholine. The ability of these neuromodulators to gate LTP and LTD at the PF-PC synapse could, at least in part, explain their effect on cerebellar-dependent learning and memory paradigms. Overall, these findings have important implications for understanding the cerebellar involvement in a series of pathological conditions, ranging from ataxia to autism. For example, PF-PC synapse dysfunctions have been identified in several murine models of spino-cerebellar ataxia (SCA) types 1, 3, 5 and 27. In some cases, the defect is specific for the AMPA receptor signaling (SCA27), while in others the mGlu1 pathway is affected (SCA1, 3, 5). Interestingly, the PF-PC synapse has been shown to be hyper-functional in a mutant mouse model of autism spectrum disorder, with a selective deletion of Pten in Purkinje cells. However, the full range of methodological approaches, that allowed the discovery of the physiological principles of PF-PC synapse function, has not yet been completely exploited to investigate the pathophysiological mechanisms of diseases involving the cerebellum. We, therefore, propose to extend the spectrum of experimental investigations to tackle this problem.