Miracle-dz/UniFAR-FTUs huggingface dataset:
DEMON: mining and monitoring evolving data

Data mining algorithms have been the focus of much research recently. In practice, the input data to a data mining process resides in a large data warehouse whose data is kept up-to-date through periodic or occasional addition and deletion of blocks of data. Most data mining algorithms have either assumed that the input data is static, or have been designed for arbitrary insertions and deletions of data records. We consider a dynamic environment that evolves through systematic addition or deletion of blocks of data. We introduce a new dimension called the data span dimension, which allows user-defined selections of a temporal subset of the database. Taking this new degree of freedom into account, we describe efficient model maintenance algorithms for frequent itemsets and clusters. We then describe a generic algorithm that takes any traditional incremental model maintenance algorithm and transforms it into an algorithm that allows restrictions on the data span dimension. In a detailed experimental study, we examine the validity and performance of our ideas.
Guidelines on the management of massive blood loss

The guideline group was selected to be representative of UKbased medical experts and included the authors of previous recommendations. Preparation of the guidelines included a review of key literature, including Cochrane Database and MEDLINE and consultation with representatives of relevant specialties. Recommendations are based on appraisal of the relevant literature and expert consensus. The writing group produced the draft guideline, which was subsequently revised by consensus by members of the Transfusion Task Force of the British Committee for Standards in Haematology. The guideline was then reviewed by a sounding board of approximately 100 UK haematologists, the British Committee for Standards in Haematology (BCSH) and the British Society for Haematology Committee and comments incorporated where appropriate. Criteria used to quote levels and grades of evidence are as outlined in appendix 3 of the Procedure for Guidelines Commissioned by the BCSH (http:// www.bcshguidelines.com/process1.asp#App3). The objective of this guideline is to provide healthcare professionals with clear guidance on the management of massive blood loss. They do not address the specific problems associated with major obstetric haemorrhage; these are being addressed by the Royal College of Obstetricians. In all cases individual patient circumstances may dictate an alternative approach.
Genome-Wide Identification, Characterization, and Expression Analysis of Four Subgroup Members of the GH13 Family in Wheat (Triticum aestivum L.)

The glycoside hydrolase 13 (GH13) family is crucial for catalyzing α-glucoside linkages, and plays a key role in plant growth, development, and stress responses. Despite its significance, its role in plants remains understudied. This study targeted four GH13 subgroups in wheat, identifying 66 GH13 members from the latest wheat database (IWGSC RefSeq v2.1), including 36 α-amylase (AMY) members, 18 1,4-α-glucan-branching enzyme (SBE) members, 9 isoamylase (ISA) members, and 3 pullulanase (PU) members. Chromosomal distribution reveals a concentration of wheat group 7 chromosomes. Phylogenetic analysis underscores significant evolutionary distance variations among the subgroups, with distinct molecular structures. Replication events shaped subgroup evolution, particularly in regard to AMY members. Subcellular localization indicates AMY member predominance in extracellular and chloroplast regions, while others localize solely in chloroplasts, confirmed by the heterologous expression of TaSEB16 and TaAMY1 in tobacco. Moreover, 3D structural analysis shows the consistency of GH13 across species. Promoter cis-acting elements are suggested to be involved in growth, stress tolerance, and starch metabolism signaling. The RNA-seq data revealed TaGH13 expression changes under drought and submergence stress, and significant expression variation was observed between strong and weak gluten varieties during seed germination using quantitative real-time PCR (qRT-PCR), correlating with seed starch content. These findings demonstrate the pivotal role of GH13 family gene expression in wheat germination, concerning variety preference and environmental stress. Overall, this study advances the understanding of wheat GH13 subgroups, laying the groundwork for further functional studies.
Diesel exhaust exposure among adolescents in Harlem: a community-driven study.

OBJECTIVES This study sought individual-level data on diesel exhaust exposure and lung function among adolescents in Harlem as part of a community-driven research agenda. METHODS High school students administered in-person surveys to seventh grade students to ascertain information on demographics, asthma history, and self-reported and maternal smoking. Urine samples were assayed for 1-hydroxypyrene (1-HP), a marker of diesel exhaust exposure, and cotinine, a marker of tobacco smoke exposure. Computer-assisted spirometry was used to measure lung function. RESULTS Three quarters (76%) of the participating students had detectable levels of 1-HP. Three students (13%) had an FEF25-75 of less than or equal to 80% of their predicted measurements, and 4 students (17%) had results between 80% and 90% of the predicted value, all of which are suggestive of possible lung impairment. CONCLUSIONS These data suggest that most adolescents in Harlem are exposed to detectable levels of diesel exhaust, a known exacerbator and possible cause of chronic lung disorders such as asthma. Community-driven research initiatives are important for empowering communities to make needed changes to improve their environments and health.
Ensembling and Clustering Approach to Gene Selection

In pattern recognition the problem of input variable selection has been traditionally focused on technological issues, e.g., performance enhancement, lowering computational requirements, and reduction of data acquisition costs. However, in the last few years, it has found many applications in basic science as a model selection and discovery technique, as shown by a rich literature on this subject, witnessing the interest of the topic especially in the field of bioinformatics. A clear example arises from DNA microarray technology that provides high volumes of data for each single experiment, yielding measurements for hundreds of genes simultaneously. In this paper, we propose a flexible method for analyzing the relevance of input variables in high dimensional problems with respect to a given dichotomic classication problem. Both linear and non-linear cases are considered. In the linear case, the application of derivative-based saliency yields a commonly adopted ranking criterion. In the non-linear case, the approach is extended by introducing a resampling technique and by clustering the obtained results for stability of the estimate. The method we propose (seeTab. 1) is termed Random Voronoi Ensemble since it is based on random Voronoi partitions [1], and these partitions are replicated by resampling, so the method actually uses an ensemble of random Voronoi partitions. Within each Voronoi region, a linear classification is performed using Support Vector Machines (SVM) with a linear kernel [4], while, to integrate the outcomes of the ensemble, we use the Graded Possibilistic Clustering technique to ensure an appropriate level of outlier insensitivity [3].
TRANCE Is Necessary and Sufficient for Osteoblast-mediated Activation of Bone Resorption in Osteoclasts

TRANCE (tumor necrosis factor–related activation-induced cytokine) is a recently described member of the tumor necrosis factor superfamily that stimulates dendritic cell survival and has also been found to induce osteoclastic differentiation from hemopoietic precursors. However, its effects on mature osteoclasts have not been defined. It has long been recognized that stimulation of osteoclasts by agents such as parathyroid hormone (PTH) occurs through a hormonal interaction with osteoblastic cells, which are thereby induced to activate osteoclasts. To determine whether TRANCE accounts for this activity, we tested its effects on mature osteoclasts. TRANCE rapidly induced a dramatic change in osteoclast motility and spreading and inhibited apoptosis. In populations of osteoclasts that were unresponsive to PTH, TRANCE caused activation of bone resorption equivalent to that induced by PTH in the presence of osteoblastic cells. Moreover, osteoblast-mediated stimulation of bone resorption was abrogated by soluble TRANCE receptor and by the soluble decoy receptor osteoprotegerin (OPG), and stimulation of isolated osteoclasts by TRANCE was neutralized by OPG. Thus, TRANCE expression by osteoblasts appears to be both necessary and sufficient for hormone-mediated activation of mature osteoclasts, and TRANCE-R is likely to be a receptor for signal transduction for activation of the osteoclast and its survival.
How Many Wi-Fi APs Does it Take to Light a Lightbulb?

The global move toward wireless access point (AP) densification has alluded toward the possibility of harvesting the unused ambient RF energy, especially in the 2.4-GHz unlicensed band, in order to power useful electronic devices, which collectively make up the so-called low energy Internet of Things (LE-IoT). Despite the huge market demand for free ambient energy and the research community's efforts in prototyping efficient rectifiers, there is, however, little knowledge about the available power densities in dense indoor and outdoor AP deployments. Obtaining this information is, therefore, vital for engineering the power requirements of LE-IoT devices and managing expectations for their subsequent commercialization. In this paper, we present power density measurements in a controlled indoor ultra-dense deployment corresponding to approximately one AP per square meter. We detail our methodology and hardware and offer a variety of ambient RF measurement results suggesting that Wi-Fi AP densification cannot solely power personal devices such as wearables, but at best can trickle charge them in the hopes of extending battery life, the main hurdle being the small form factor of such mobile devices. In contrast, our measurements suggest that household devices, such as smoke detectors, can be powered by ambient RF harvesting. To this end, AP densification aids in increasing the total available power density, but also in distributing a smooth blanket of available RF energy thus minimizing harvesting-holes.
Evaluation of in-situ Compositions in Retrograde Gas Condensate Fields

Summary Production from gas condensate fields cause low condensate recoveries at surface facilities because of in-situ retrograde condensation and condensate build-up in the reservoir particularly in the vicinity of the wellbore. During depletion, the total composition of in-situ fluid (gas and condensate composition) changes from initial reservoir composition as pressure decreases to values less than Saturation (dew-point) pressure. This paper extends the line of the study conducted by our team (Nasriani et al., 2016) to attain initial in-situ composition from gas and liquid compositions taken from separator during several depletion stages. In our previous work, based on the composition of the mixed sample and initial reservoir composition, a set of novel correlations was developed for estimating initial gas condensate reservoir composition. But as carbon number increased, the predicted compositions by correlation became less accurate. In this study, in order to improve the prediction of in-situ compositions, the components with similar carbon numbers were grouped into a category. The generalised reduced gradient (GRG) algorithm of iteration was used to tune the constant and exponents of the correlation based on available field data.
CARACTERIZAÇÃO MORFOLÓGICA DE CULTIVARES DE ARROZ VISANDO A CERTIFICAÇÃO DA PUREZA VARIETAL * Morphological characteristics of rice cultivars; application for variety purity certification

RESUMOCom o presente trabalho, objetivou-se avaliar a eficienciados descritores morfologicos, na caracterizacao de cultivarescomerciais de arroz (Oryza sativa L.), servindo como suporte as empresas produtoras de sementes na identificacao de cultivares,assim como as exigencias da Lei de Protecao de Cultivares. Foram caracterizadas as cultivares de arroz Carisma, IAC 202, Confianca,Douradao, Guarani, Primavera, Canastra e Caiapo. O estudo consistiu de dois experimentos, o primeiro conduzido em casa-de-vegetacao, quando os genotipos foram caracterizados utilizando-se dos descritores morfologicos recomendados para o registro eprotecao de cultivares. O segundo experimento foi conduzido em uma area de producao de sementes e consistiu na identificacao, porparte de avaliadores, de variedades de arroz contaminantes propositalmente distribuidas junto as cultivares em estudo. Concluiu-seque os descritores morfologicos sao uteis, porem, nao suficientes para a caracterizacao e diferenciacao de cultivares de arroz. Ascaracteristicas morfologicas observadas em sementes e plantas apos a antese sao as mais adequadas para a caracterizacao e diferenciacaode cultivares. Os genotipos de arroz de sequeiro apresentam grande similaridade morfologica.Termos para indexacao: Arroz, marcadores morfologicos, distincao varietal, Oryza sativa L.ABSTRACTThis study had the objective of evaluating the efficiency of morphological markers as descriptors for commercial rice cultivars(Oryza sativa L.) to be used in cultivar identification by seed companies, as well as, to fulfill the requirements for cultivar protectionlaw. The studied cultivars were: Confianca, IAC 202, Carisma, Primavera, Guarani, Douradao, Canastra, and Caiapo. This studyconsisted of two experiments: one, conducted in greenhouse, where the varieties were characterized based on morphological descriptorsrecommended by protection cultivar law; the other, done in a seed production field that consisted in identification of rice contaminantvarieties distributed among the studied cultivars. The morphological descriptors were useful, but not enough to characterize anddistict upland rice cultivars; seeds and plants morphological characteristics after anthesis were the most suitable for the characterizationand discrimination of varieties; and also, the upland rice genotypes had high morphological similarities.Index terms: Rice, morphological markers, varietal distinction, Oryza sativa L. (Recebido em 22 de setembro de 2004 e aprovado em 16 de fevereiro de 2006)
Algorithms to Improve the Reparameterization of Spherical Mappings of Brain Surface Meshes

A spherical map of a cortical surface is often used for improved brain registration, for advanced morphometric analysis (eg, of brain shape), and for surface‐based analysis of functional signals recorded from the cortex. Furthermore, for intersubject analysis, it is usually necessary to reparameterize the surface mesh into a common coordinate system. An isometric map conserves all angle and area information in the original cortical mesh; however, in practice, spherical maps contain some distortion. Here, we propose fast new algorithms to reduce the distortion of initial spherical mappings generated using one of three common spherical mapping methods. The algorithms iteratively solve a nonlinear optimization problem to reduce distortion. Our results demonstrate that our correction process is computationally inexpensive and the resulting spherical maps have improved distortion metrics. We show that our corrected spherical maps improve reparameterization of the cortical surface mesh, such that the distance error measures between the original and reparameterized surface are significantly decreased.
Antinociceptive Effect of Hydantoin 3-Phenyl-5-(4-ethylphenyl)-imidazolidine-2,4-dione in Mice

Imidazolidine derivatives, or hydantoins, are synthetic compounds with different therapeutic applications. Many imidazolidine derivatives have psychopharmacological properties, such as phenytoin, famous for its anticonvulsant efficacy, but also effective in the treatment of neuropathic pain. The hydantoin, 3-phenyl-5-(4-ethylphenyl)-imidazolidine-2,4-dione (IM-3), synthesized from the amino acid, glycine, was selected for psychopharmacological studies in mice on the basis of its chemical and structural similarity with phenytoin. The first step of this study was to define the LD50, which determined the doses of 50, 100 and 200 mg/kg for subsequent tests. The results obtained from the behavioral screening indicated that IM-3 produces decreased ambulation and analgesia in mice. Motor coordination and anxiety behavior were not affected by treatment with IM-3, as observed in the rotarod and elevated plus-maze tests, respectively. Regarding its antinociceptive properties, IM-3 showed efficacy in the acetic acid-induced writhing test by increasing the latency of the first writhe and reducing the number of writhes, as well as reducing the paw licking time in the second phase of the formalin test. The behavior of treated animals exposed to the hot plate test, however, did not differ from that of the control group. These data suggest that IM-3 has antinociceptive effects in mice, which is probably mediated by anti-inflammatory mechanisms.
Challenges in evaluation standards for public investment projects (PIP) in Lao PDR: Evaluation of quality of life by a combination of OECD, ADB, and PCAP evaluation approaches

Minority people are living in society in Laos, and the Lao government is struggling to promote their lives. In rural areas, minority people are having difficulties accessing good food and safe drink intake ‘GFSDI’. In this survey, the author 1) investigated the GFSDI of minority people by using logistic regression, and to find the effectiveness and efficiency of the PIP projects via the result of GFSDI; 2) used an evaluation approach modified from OECD, ADB, and PCAP, which is called the mixed economic evaluation ‘ECEVA’, to find the effectiveness and efficiency of the PIP projects by employing ECEVA and AECEVA. The author used the primary set of data collected from the field survey by interviewing 518 villagers who were minority people and worked with the PIP projects in 11 provinces. As a result, the AECEVA showed that PIP projects were quite effective and efficient in supporting the quality of life of minority people in rural areas. Interestingly, the result of logistic regression also showed that the GFSDI of minorities could demonstrate the effectiveness and efficiency of the PIP projects in Laos.
Inactive GroEL Monomers Can Be Isolated and Reassembled to Functional Tetradecamers That Contain Few Bound Peptides (*)

For the first time, it has been shown that GroEL can be converted from tetradecamers (14-mers) to monomers under conditions commonly used for the preparation of this chaperonin. The essential requirements are the simultaneous presence of nucleotides such as MgATP or MgADP and a solid-phase anion-exchange medium. The monomers that are formed are metastable in that they only reassemble to a small degree in the absence of additives. These results are in keeping with previous studies on high pressure dissociation that showed the separated monomers display conformational plasticity and can undergo conformational relaxation when relieved of the constraints of the quaternary structure in the oligomer (Gorovits, B., Raman, C. S., and Horowitz, P. M.(1995) J. Biol. Chem. 270, 2061-2066). The monomers display greatly enhanced hydrophobic exposure to the probe 1,1′-bis(4-anilino)naphthalene-5,5′-disulfonic acid, although they are not active in folding functions, and they are unable to form complexes with partially folded rhodanese. The monomers can be completely reassembled to 14-mers by incubation in 1 M ammonium sulfate. There is no evidence of intermediates in the reassembly process. Compared with the original oligomers, the reassembled 14-mers have (a) very low levels of polypeptide contaminants and tryptophan-like fluorescence, two problems that previously hampered spectroscopic studies of GroEL structure and function; (b) functional properties that are very similar to the original material; (c) considerably decreased hydrophobic exposure in the native state; and (d) a similar triggered exposure of hydrophobic surfaces after treatment with urea or spermidine. This study demonstrates that the quaternary structure of GroEL is more labile than previously thought. These results are consistent with suggestions that nucleotides can loosen subunit interactions and show that changes in quaternary structure can operate under conditions where GroEL function has been demonstrated.
Central Nervous System Melanoma: Report of two cases

Primary brain melanomas are exceedingly rare, and metastasis outside of the central nervous system is an uncommon occurrence. The patients initially presented with an intraparenchymal hematoma with associated symptoms. Extensive diagnostic tests did not reveal any tumor-related or vascular patterns contributing to these bleedings. A comprehensive surgical resection was conducted, and the diagnosis of Central Nervous System (CNS) melanoma was confirmed through histological examination. Despite the generally poor prognosis associated with malignant melanomas, the combination of complete surgical resection and emerging therapies is extending overall survival and enhancing the quality of life. In cases where primary brain melanoma is suspected, even in the presence of extracerebral metastasis, aggressive treatment may be a viable consideration.
RFexpress! — Exploiting the wireless network edge for RF-based emotion sensing

We present RFexpress! the first-ever network-edge based system to recognize emotion from movement, gesture and pose via Device-Free Activity Recognition (DFAR). With the proliferation of the IoT, also wireless access points are deployed at increasingly dense scale. in particular, this includes vehicular nodes (in-car WiFi or Bluetooth), office (Wlan APs, WiFi printer or projector) and private indoor domains (home WiFi mesh, Wireless media access), as well as public spaces (City/open WiFi, Cafes, shopping spaces). Processing RF-fluctuation at such edge-devices, enables environmental perception. In this paper, we focus on the distinction between neutral and agitated emotional states of humans from RF-fluctuation at the wireless network edge in realistic environments. In particular, the system is able to detect risky driving behaviour in a vehicular setting as well as spotting angry conversations in an indoor environment. We also study the effectiveness of edge-based DFAR emotion and activity recognition systems in real environments such as cafes, malls, outdoor and office spaces. We measure radio characteristics in these environments at different days and times and analyse the impact of variations in the Signal to Noise Ratio (SNR) on the accuracy of DFAR emotion and activity recognition. In a case study with 5 subjects, we then exploit the limits of edge-based DFAR by deriving critical SNR values under which activity and emotion recognition results are no longer reliable. In case studies with 8 and 5 subjects the system further could achieve recognition accuracies of 82.9% and 64% for vehicular and stationary wireless network edge in the wild (non-laboratory noisy environments and non-scripted, natural individual behaviour patterns).