Miracle-dz/UniFAR-FTUs huggingface dataset:
Gas Exchange and Carbon Partitioning in the Leaves of Celery (Apium graveolens L.) at Various Levels of Root Zone Salinity

Both mannitol and sucrose (Suc) are primary photosynthetic products in celery (Apium graveolens L.). In other biological systems mannitol has been shown to serve as a compatible solute or osmoprotectant involved in stress tolerance. Although mannitol, like Suc, is translocated and serves as a reserve carbohydrate in celery, its role in stress tolerance has yet to be resolved. Mature celery plants exposed to low (25 mM NaCl), intermediate (100 mM NaCl), and high (300 mM NaCl) salinities displayed substantial salt tolerance. Shoot fresh weight was increased at low NaCl concentrations when compared with controls, and growth continued, although at slower rates, even after prolonged exposure to high salinities. Gas-exchange analyses showed that low NaCl levels had little or no effect on photosynthetic carbon assimilation (A), but at intermediate levels decreases in stomatal conductance limited A, and at the highest NaCl levels carboxylation capacity (as measured by analyses of the CO2 assimilation response to changing internal CO2 partial pressures) and electron transport (as indicated by fluorescence measurements) were the apparent prevailing limits to A. Increasing salinities up to 300 mM, however, increased mannitol accumulation and decreased Suc and starch pools in leaf tissues, e.g. the ratio of mannitol to Suc increased almost 10-fold. These changes were due in part to shifts in photosynthetic carbon partitioning (as measured by 14C labeling) from Suc into mannitol. Salt treatments increased the activity of mannose-6-phosphate reductase (M6PR), a key enzyme in mannitol biosynthesis, 6-fold in young leaves and 2-fold in fully expanded, mature leaves, but increases in M6PR protein were not apparent in the older leaves. Mannitol biosynthetic capacity (as measured by labeling rates) was maintained despite salt treatment, and relative partitioning into mannitol consequently increased despite decreased photosynthetic capacity. The results support a suggested role for mannitol accumulation in adaptation to and tolerance of salinity stress.
Perceptual Soundfield Reconstruction in Three Dimensions via Sound Field Extrapolation

Perceptual sound field reconstruction (PSR) is a spatial audio recording and reproduction method based on the application of stereophonic panning laws in microphone array design. PSR allows rendering a perceptually veridical and stable auditory perspective in the horizontal plane of the listener, and involves recording using near-coincident microphone arrays. This paper extends the PSR concept to three dimensions using sound field extrapolation carried out in the spherical-harmonic domain. Sound field rendering is performed using a two-level loudspeaker rig. An active-intensity-based analysis of the rendered sound field shows that the proposed approach can render direction of monochromatic plane waves accurately.
A Three Phase Semantic Web Matchmaker

Since using environments that are made according to the service oriented architecture, we have more effective and dynamic applications. Semantic matchmaking process is finding valuable service candidates for substitution. It is a very important aspect of using semantic Web Services. Our proposed matchmaker algorithm performs semantic matching of Web Services on the basis of input and output descriptions of semantic Web Services matching. This technique takes advantages from a graph structure and flow networks. Our novel approach is assigning matchmaking scores to semantics of the inputs and outputs parameters and their types. It makes a flow network in which the weights of the edges are these scores, using FordFulkerson algorithm, we find matching rate of two web services. So, all services should be described in the same Ontology Web Language. Among these candidates, best one is chosen for substitution in the case of an execution failure. Our approach uses the algorithm that has the least running time among all others that can be used for bipartite matching. The importance of problem is that in real systems, many fundamental problems will occur
Estimating Position and Orientation of an Unmanned Guided Vehicle with Ultrasound and Radio Frequency Sensing

Abstract: Conventional method of finding location of moving an Unmanned Guided Vehicle (UGV) in pre-defined area is by Distance Measurement Equipment (DME) based on Ultrasound and triangulation technique. In many systems the ultrasound transmitter requires to be in line of sight of receiver to reduce the error. In order to overcome this problem powerful transmitters are used to ensure omni directional transmission over large distances resulting in cone shape propagation. In this cone propagation the signal may not be visible in many areas and triangulation is not possible. This paper describes a unique triangulation system based on two different ultrasound signals and Radio Frequency using four transmitters’ at different locations and eight receivers fixed on an UGV. This method requires no line of sight or specific angle to receive the signal from transmitter. Thus vehicle can rotate in any angle and move anywhere in a given specific region. At the same time it was possible to estimate the position coordinates and orientation of vehicle. The new system shows that the vehicle can be more flexible and angular restriction does not bind its movement.
Effect of active immunization against GnRH-I on the reproductive function in cat.

This study was designed to explore the effect of active immunization against maltose binding protein-gonadotropin releasing hormone I hexamer (MBP-GnRH-I6) on the reproductive function in cats. Each immunized cat was administered twice intramuscularly in the neck at 16 and 20 weeks old. The concentrations of the testosterone and estradiol and the level of anti-GnRH-I antibody in the serum were measured by radioimmunoassay and ELISA, respectively. The results showed that the weight and size of testicles and ovaries, and the concentrations of serum testosterone and estradiol in the immunized animals were lower than those of the control cats (P < 0.05), but that the levels of anti-GnRH-I antibody were significant higher compared to control animals (P < 0.05). Testicular tissues from the immunized male cats showed that seminiferous tubules were depauperate with the lumen relatively empty and that the differentiation of spermatogonia was not obvious. Tissues from the immunized female cats showed that the ovaries had many primordial follicles and primary follicles, but no secondary follicle was observed. These results showed active immunization against MBP-GnRH-I6 could make the gonads atrophy and reduce the concentrations of gonadal hormones, which suggested that MBP-GnRH-I6 was a very effective immunogen in the cat.
Perinatal and crowding-related risk factors for invasive pneumococcal disease in infants and young children: a population-based case-control study.

BACKGROUND Denmark's systems of registry-based data offer a unique opportunity to examine, on a population basis, risk factors for invasive pneumococcal disease (IPD) relating to perinatal and crowding exposures among children. The main objective of this study was to identify the role of familial and day care factors in the risk of IPD among unvaccinated infants and children. METHODS A total of 1381 children aged 0-5 years old who experienced IPD were identified from a national surveillance program of IPD in Denmark. Risk factors were assessed in a matched, nested, case-control study that assigned 10 population control subjects to every case patient. Exposure information was obtained from several population-based, person-identifiable Danish registries. RESULTS Preterm birth and low birth weight significantly increased the risk of IPD among infants. In infants 0-5 months of age, the risk of IPD was high among infants who had older siblings, compared with infants of the same age who had no older siblings (adjusted rate ratio [aRR], 3.38; 95% confidence interval, 2.11-5.42), whereas the aRR was low (aRR, 0.56; 95% confidence interval, 0.47-0.65) in children aged 6-23 months. Day care attendance, compared with home care, increased the aRR of IPD 0-2 months after enrollment in a day care program (aRR, 2.28; 95% confidence interval, 1.73-3.00), whereas the aRR was 0.70; (95% confidence interval, 0.46-1.06) > or = 6 months after enrollment in children aged 6-23 months. CONCLUSIONS During infancy (age, 0-6 months), risk of IPD is associated with low birth weight, presumably because of lower levels of passively acquired maternal antibody. During early childhood, exposure to other young children (either siblings or through day care attendance) is clearly associated with IPD, but natural exposure appears to occur rapidly and confer durable immunity.
A 41-year-old Female Presenting with Sicca Syndrome

Objective: To describe a case of Sicca syndrome, review the literature on and discuss the diagnostic criteria for Sjögren Syndrome. Methods: Design: Case report Setting: Private clinic Patient: One Results: A 41-year-old female presenting with throat dryness, dry eyes, bilateral parotid enlargement, vaginal dryness and multiple joint pains previously seen by four specialists over three decades was finally diagnosed with Sjögren syndrome. Conclusion: Sjögren syndrome presents uncommonly. As the presentation and clinical course should be taken as a whole, and no single test can be considered as a gold standard for its diagnosis, the disease entity may actually be under diagnosed, misdiagnosed or frequently present as diagnostic dilemmas. A comprehensive history and physical examination beyond the usual focus of the otorhinolaryngologic evaluation is the key for the astute clinician. Our experience may indicate a need for further evaluation of the EU revised criteria for Sjögren syndrome classification in the local setting.
Evaluation of Source-wise Missing Data Techniques for the Prediction of Parkinson’s Disease Using Smartphones

Multi-source datasets often present the challenge of source-wise missing data which can render large portions of the dataset inaccessible. The applicability of traditional missing data techniques on multi-source datasets is poorly understood. We present the first quantitative evaluation of the state-of-the-art missing data techniques as applied to a freely available dataset of smart-phone recordings from Parkinsonian patients wherein source-wise missing data is simulated. The classification accuracy and imputation error of five missing data techniques, including a multi-modal autoencoder and multi-source ensemble learning, are compared at varying levels of missingness. These results demonstrate the relative applicability of each technique under different conditions and subsequently highlight the challenges of source-wise missing on remotely collected datasets. Specifically, multi-source ensemble learning proves to be a highly successful alternative to the traditional imputation techniques when a majority of observations possess missing data.
Achievable Rates of UAV-Relayed Cooperative Cognitive Radio MIMO Systems

We study the achievable rate of an uplink MIMO cognitive radio system where the primary user (PU) and the secondary user (SU) aim to communicate to the closest primary base station (BS) via a multi-access channel through the same unmanned aerial vehicle (UAV) relay. The SU message is then forwarded from the primary BS to the secondary network with a certain incentive reward as a part of the cooperation protocol between both the networks. A special linear precoding scheme is proposed to enable the SU to exploit the PU free eigenmodes. We analyze two scenarios in which the UAV relay gain matrix is either fixed or optimized. We derive the optimal power allocation that maximizes the achievable rate of the SU respecting power budget, interference, and relay power constraints. Numerical results highlight the cognitive rate gain of our proposed scheme with respect to various problem parameters. We also highlight the effect of UAV altitude on the SU and PU rates. Finally, when the relay matrix is optimized, we show that the PU rate is remarkably enhanced and that the SU rate is only improved at high-power regime.
Impact of autoimmune rheumatic diseases on birth outcomes: a population-based study

Objectives Autoimmune rheumatic diseases (ARDs) affect women of childbearing age and have been associated with adverse birth outcomes. The impact of diseases like ankylosing spondylitis and psoriatic arthritis (PsA) on birth outcomes remains less studied to date. Our objective was to evaluate the impact of ARDs on preterm birth (PTB), congenital anomalies, low birth weight (LBW) and small for gestational age (SGA), in a large cohort of women. Methods We conducted a propensity score-matched analysis to predict ARD from a retrospective birth cohort of all live, singleton births in California occurring between 2007 and 2012. Data were derived from birth certificate records linked to hospital discharge International Classification of Diseases, ninth revision codes. Results We matched 10 244 women with a recorded ARD diagnosis (rheumatoid arthritis (RA), systemic lupus erythematosus (SLE), antiphospholipid syndrome, PsA); ankylosing spondylitis and juvenile idiopathic arthritis (JIA) to those without an ARD diagnosis. The adjusted OR (aOR) of PTB was increased for women with any ARD (aOR 1.93, 95% CI 1.78 to 2.10) and remained significant for those with RA, SLE, PsA and JIA. The odds of LBW and SGA were also significantly increased among women with an ARD diagnosis. ARDs were not associated with increased odds of congenital anomalies. Conclusion Consistent with prior literature, we found that women with ARDs are more likely to have PTB or deliver an SGA infant. Some reassurance is provided that an increase in congenital anomalies was not found even in this large cohort.
Weight Loss with Magnesium Alloys

New design and processing approaches for magnesium-based alloys are offering a variety of opportunities in lightweight and energy-efficient applications. The compelling need for lightweight, energy-efficient, environmentally benign engineering systems is driving the development of a wide range of structural and functional materials for energy generation, energy storage, propulsion, and transportation. These challenges motivate wider spread use of magnesium—the eighth most common element in the earth's crust and also extractable from seawater. In addition, the ease of recycling, compared with polymers, makes magnesium alloys environmentally attractive. Importantly, with a density of 1.74 g/cm3—about 30% less than aluminum, one-quarter that of steel, and nearly the same as many polymers—magnesium is attractive for lightweight structural systems and, most notably, automotive systems. A typical car weighing 1525 kg currently contains about 975 kg of steel, 127 kg of Al, 114 kg of polymeric materials, and 5 to 6 kg of magnesium (1). It is estimated that 22.5 kg of mass reduction would improve fuel efficiency by around 1%; thus, automotive manufacturers worldwide have goals to increase the Mg content of automobiles to between 45 and 160 kg (1, 2).
MOTOR EVOKED POTENTIALS IN MOTOR NEURON DISEASE: PARAMETERS OF EVALUATION AND ITS RELATION TO DISEASE SEVERITY

Background: Transcranial magnetic stimulation (TMS) is a technique that can activate cortical motor areas and the corticospinal tract without causing discomfort to the patients. Objective: To evaluate the parameters of MEP induced by TMS in MND and its relation to the severity of the disease. Methodology: Twenty five subjects with motor neuron disease (MND) who had been diagnosed as MND using the standard clinical and electrophysiological studies (nerve conduction studies, EMG and the somatosensory evoked potential studies) had been subjected to TMS and the MEP parameters {threshold, central motor conduction time (CMCT), amplitude percentage quotient, phases and duration of the MEPs} were determined. Matched healthy persons were selected as control. Functional evaluation and disease severity assessment had been scored using the ALS Functional Rating Scale (ALSFRS) and the ALS Severity Score (ALSSS) respectively and compared to the control group. Results: A statistical significant difference of all the motor evoked potentials (MEP) parameters of the studied patients and the scale measurements were present when compared with the control group. The mean central conduction time (CMCT) was correlated with the severity of the disease while the amplitude changes were evident in late stages especially when associated with bulbar manifestations whereas
On the Fundamental Limits of Random Non-Orthogonal Multiple Access in Cellular Massive IoT

Machine-to-machine (M2M) constitutes the communication paradigm at the basis of Internet of Things vision. M2M solutions allow billions of multi-role devices to communicate with each other or with the underlying data transport infrastructure without, or with minimal, human intervention. Current solutions for wireless transmissions originally designed for human-based applications thus require a substantial shift to cope with the capacity issues in managing a huge amount of M2M devices. In this paper, we consider the multiple access techniques as promising solutions to support a large number of devices in cellular systems with limited radio resources. We focus on non-orthogonal multiple access (NOMA) where, with the aim to increase the channel efficiency, the devices share the same radio resources for their data transmission. This has been shown to provide optimal throughput from an information theoretic point of view. We consider a realistic system model and characterize the system performance in terms of throughput and energy efficiency in an NOMA scenario with a random packet arrival model, where we also derive the stability condition for the system to guarantee the performance.
Prestin and the good vibrations

In a recent paper published in the Biochemical Journal, Lolli et al. presented evidence that the C-terminal STAS (sulfate transporter and anti-sigma factor antagonist) domain of the motor protein prestin possesses an anion-binding site. This discovery might shed light on an aspect of the function of this mysterious and fascinating protein that is crucial for the human hearing system.
Investigating the potential role of multi-drug resistance protein (MRP) transporters in fetal to maternal glyburide efflux in the human placenta

Summary Glyburide, a drug used to treat gestational diabetes has previously been shown not to be measurable in fetal blood, and to be transferred from the fetal to the maternal circulation against a concentration gradient. The objective of the study is to determine whether indomethacin, an inhibitor of the multi-drug resistance family (MRP) of transporters is involved in the active efflux of glyburide from the fetus to the mother. Using the dually perfused human placental cotyledon model, 12 perfusions were performed of both glyburide and indomethacin concomitantly. The rate of transfer of glyburide in the presence of inhibitor was not different from the rate of transfer of glyburide in the absence of inhibitor. Furthermore, our study suggests that MRP1, 2 or 3 may be only minimally involved in the transport of glyburide across the human placenta. These results pose other ABC transporters, such as likely candidates for the placental transfer of glyburide.
Mechanization of an Oracle in a Debugging System

We shall make use of a programming calculus to derive the correct result a program is expected to compute. In this way, the decision by an oracle whether or not a result is correct can be derived formally from a specification (model) of the program, and thus the oracle can be mechanized. The debugging system consists mainly of a derivation editor and a fault finding program that collects an erroneous procedure.
The role of maintenance proteins in the preservation of epithelial cell identity during mammary gland remodeling and breast cancer initiation

During normal postnatal mammary gland development and adult remodeling related to the menstrual cycle, pregnancy, and lactation, ovarian hormones and peptide growth factors contribute to the delineation of a definite epithelial cell identity. This identity is maintained during cell replication in a heritable but DNA-independent manner. The preservation of cell identity is fundamental, especially when cells must undergo changes in response to intrinsic and extrinsic signals. The maintenance proteins, which are required for cell identity preservation, act epigenetically by regulating gene expression through DNA methylation, histone modification, and chromatin remodeling. Among the maintenance proteins, the Trithorax (TrxG) and Polycomb (PcG) group proteins are the best characterized. In this review, we summarize the structures and activities of the TrxG and PcG complexes and describe their pivotal roles in nuclear estrogen receptor activity. In addition, we provide evidence that perturbations in these epigenetic regulators are involved in disrupting epithelial cell identity, mammary gland remodeling, and breast cancer initiation.
Distribution of Solution in the Epidural Space: Examination by Cryomicrotome Section

Background and Objectives The routes of distribution and barriers to flow of solutions in the epidural space are incompletely determined. This study examined macroscopic details of epidural injectate spread in postmortem humans by cryomicrotome imaging. Methods Soon after death, 3 nonembalmed adult human subjects were injected with ink through epidural catheters inserted by standard techniques. Following freezing, microtome sectioning was performed to reveal anatomic features down to 100 μm. To control for effects of death, an adult baboon was injected during general anesthesia and subsequently examined in the same fashion. Results Injected ink was readily evident and showed spread as rivulets through numerous small channels rather than as a unified advancing front. The fascia that extends laterally from the posterior longitudinal ligament is an important barrier restricting solution flow. Solution preferentially traveled along the nerve root sheath through the intervertebral foramen. Conclusions Distribution of solution in the epidural space is nonuniform. Rather than a uniform advancing front, spread is directed among paths between structures according to pressures by which they are compressed. No structural barriers block flow through the intervertebral foramina or spinal canal other than the fascia of the posterior longitudinal ligament.