Miracle-dz/UniFAR-FTUs huggingface dataset:
Intention-mining: A solution to process participant support in process aware information systems

While the advantages of flexible business processes have been highly recognized by the academia and organizations, the research focus has recently shifted to its trade-offs and how the negative consequences could be minimized. This research addressed the problem consisting of the difficulties encountered by process participants when interacting with flexible process aware information systems. In order to overcome these difficulties, several approaches for guiding or supporting the process participants during enactment, based on process mining, have been proposed. However, these solutions lacked the suitable semantics for humans reasoning and decision making during enactment as they provided recommendations at a low granularity level. Consequently, the objective of this research was twofold. First, the implications for agents, process participant and process administrator, of integrating flexible processes into process aware information systems were analyzed through a systematic literature study. Secondly, using design science, two artifacts were created to solve the problematic situation: 1) an innovative process mining technique that discovers the intentional model of the executable process in an unsupervised manner, and 2) a recommendation tool that formulates recommendations as intentions and confidence factors, based on partial traces and probabilistic calculus. The artifacts were evaluated in a case study with a Childcare application supporting flexible process enactment with a datadriven approach. The experiments revealed that the intention mining technique had a precision of 0.69 in discovering the correct intentions. Regarding the recommendation tool, the majority of the participants agreed on the improved support for decision making, offered by the recommendations given as intentions in comparison to recommendations given as activities, while a majority disagreed on the utility of the confidence factors attached to each recommendation.
Revision of Campylobacter, Helicobacter, and Wolinella taxonomy: emendation of generic descriptions and proposal of Arcobacter gen. nov.

Hybridization experiments were carried out between DNAs from more than 70 strains of Campylobacter spp. and related taxa and either 3H-labeled 23S rRNAs from reference strains belonging to Campylobacter fetus, Campylobacter concisus, Campylobacter sputorum, Campylobacter coli, and Campylobacter nitrofigilis, an unnamed Campylobacter sp. strain, and a Wolinella succinogenes strain or 3H- or 14C-labeled 23S rRNAs from 13 gram-negative reference strains. An immunotyping analysis of 130 antigens versus 34 antisera of campylobacters and related taxa was also performed. We found that all of the named campylobacters and related taxa belong to the same phylogenetic group, which we name rRNA superfamily VI and which is far removed from the gram-negative bacteria allocated to the five rRNA superfamilies sensu De Ley. There is a high degree of heterogeneity within this rRNA superfamily. Organisms belonging to rRNA superfamily VI should be reclassified in several genera. We propose that the emended genus Campylobacter should be limited to Campylobacter fetus, Campylobacter hyointestinalis, Campylobacter concisus, Campylobacter mucosalis, Campylobacter sputorum, Campylobacter jejuni, Campylobacter coli, Campylobacter lari, and "Campylobacter upsaliensis. " Wolinella curva and Wolinella recta are transferred to the genus Campylobacter as Campylobacter curvus comb. nov. and Campylobacter rectus comb. nov., respectively. Bacteroides gracilis and Bacteroides ureolyticus are generically misnamed and are closely related to the genus Campylobacter. Campylobacter nitrofigilis, Campylobacter cryaerophila, and an unnamed Campylobacter sp. strain constitute a new genus, for which the name Arcobacter is proposed; this genus contains two species, Arcobacter nitrofigilis comb. nov. (type species) and Arcobacter cryaerophilus comb. nov. Wolinella succinogenes so far is the only species of the genus Wolinella. The genus Helicobacter is also emended; Campylobacter cinaedi and Campylobacter fennelliae are included in this genus as Helicobacter cinaedi comb. nov. and Helicobacter fennelliae comb. nov., respectively. The genus "Flexispira," with "Flexispira rappini" as the only species, is closely related to the genus Helicobacter. The free-living, sulfur-reducing campylobacters do not belong to any of these genera; they probably constitute a distinct genus within rRNA superfamily VI.
Biologically active synthetic peptides as probes of embryonic development: a competitive peptide inhibitor of fibronectin function inhibits gastrulation in amphibian embryos and neural crest cell migration in avian embryos

We describe a new method for analyzing embryonic events dependent on a specific peptide recognition signal. A short, specific amino acid sequence in fibronectin has been implicated as a recognition site in fibronectin-mediated interactions. Fibroblast adhesion to fibronectin is competitively inhibited by certain synthetic peptides, including the decapeptide Arg-Gly-Asp-Ser-Pro-Ala-Ser-Ser-Lys-Pro, which appears to contain the cell recognition sequence. We found that this peptide inhibited both amphibian gastrulation and avian neural crest cell migration in vivo, as well as the attachment and migration of neural crest cells in vitro. These processes are major cell migratory events previously suggested to involve fibronectin. Negative controls included another conserved fibronectin peptide from the collagen-binding region containing the sequence Cys-Gln-Asp-Ser-Glu-Thr-Arg-Thr-Phe-Tyr and another peptide. Our results demonstrate the feasibility of using synthetic peptides directed at recognition sites in extracellular proteins as probes of morphogenetic processes, and they provide further support for the hypothesis that fibronectin is involved in gastrulation and neural crest cell migration.
“Jumping to conclusions” in delusion-prone participants: an experimental economics approach

Introduction That delusional and delusion-prone individuals “jump to conclusions” on probabilistic reasoning tasks is a key finding in cognitive neuropsychiatry. Here we focused on a less frequently investigated aspect of “jumping to conclusions” (JTC): certainty judgments. We incorporated rigorous procedures from experimental economics to eliminate potential confounds of miscomprehension and motivation and systematically investigated the effect of incentives on task performance. Methods Low- and high-delusion-prone participants (n = 109) completed a series of computerised trials; on each trial, they were shown a black or a white fish, caught from one of the two lakes containing fish of both colours in complementary ratios. In the betting condition, participants were given £4 to distribute over the two lakes as they wished; in the control condition, participants simply provided an estimate of how probable each lake was. Deviations from Bayesian probabilities were investigated. Results Whereas high-delusion-prone participants in both the control and betting conditions underestimated the Bayesian probabilities (i.e. were conservative), low-delusion-prone participants in the control condition underestimated but those in the betting condition provided accurate estimates. In the control condition, there was a trend for high-delusion-prone participants to give higher estimates than low-delusion-prone participants, which is consistent with previous reports of “jumping to conclusions” in delusion-prone participants. However, our findings in the betting condition, where high-delusion-prone participants provided lower estimates than low-delusion-prone participants (who were accurate), are inconsistent with the jumping-to-conclusions effect in both a relative and an absolute sense. Conclusions Our findings highlight the key role of task incentives and underscore the importance of comparing the responses of delusion-prone participants to an objective rational standard as well as to the responses of non-delusion-prone participants.
Evaluation of Voids in the Mineral Aggregate for HMA Paving Mixtures

This study was undertaken to (a) reexamine the rationale behind the minimum voids in the mineral aggregate (VMA) values currently being used, and (b) quantify the relationship between various asphalt film thicknesses and the aging characteristics of the hot mix asphalt (HMA) mix, so that an optimum film thickness desirable for satisfactory mix durability could be established. The optimum film thickness could then be used to establish VMA requirements. Mixes prepared with asphalt binder film thickness ranging from about 4 to 13 microns were subjected to accelerated aging using Strategic Highway Research Program (SHRP) procedures to simulate both short and long term aging. Both the aggregate (RD) and the asphalt cement (AAM-1) used in this study were obtained from the SHRP Materials Reference Library. The aged, compacted mix was tested for tensile strength, tensile strain at failure and resilient modulus. The aged asphalt cement was recovered and tested for penetration, viscosity, complex between various asphalt film thicknesses and the aging characteristics of the HMA mix, so that an optimum film thickness desirable for satisfactory mix durability could be established. The optimum film thickness could then be used to establish modulus and phase angle. Aging indices were obtained from these tests, and the relationship between film thickness and the aged mix/aged asphalt cement properties were determined using regression analysis. For the particular aggregate/asphalt cement combination used in this study, it was found that accelerated aging would occur if the asphalt binder film thickness was less than 9 - 10 microns in an HMA mixture compacted to 8% air void content. The minimum VMA required to accommodate this optimum asphalt film thickness and 4% air void content was also calculated.
Conjugate gradient method for dual-dual mixed formulations

We deal with the iterative solution of linear systems arising from so-called dual-dual mixed finite element formulations. The linear systems are of a two-fold saddle point structure; they are indefinite and ill-conditioned. We define a special inner product that makes matrices of the two-fold saddle point structure, after a specific transformation, symmetric and positive definite. Therefore, the conjugate gradient method with this special inner product can be used as iterative solver. For a model problem, we propose a preconditioner which leads to a bounded number of CG-iterations. Numerical experiments for our model problem confirming the theoretical results are also reported.
Powder Particle Size Measurement with Digital Image Processing Using Matlab

The application of powder particle size measurement in engineering field are introduced, the major powder particle size research methods are also included. Furthermore we analyzed the characteristics of these methods. Based on these, we proposed a method, which makes full use of Matlab to process and analyze the SEM image of powders to get powder particle size and the distribution, and the method achieve a good effect. Finally, In order to verify the processing method, the authors performed an example of the approach. Based on the results, it can be confirmed, therefore, the method using MATLAB is convenient to analyze the powder particle size.
CLICK : Clustering Categorical Data using K-partite Maximal Cliques

Clustering is one of the central data mining problems and numerous approaches have been proposed in this field. However, few of these methods focus on categorical data. The categorical techniques that do exist have significant shortcomings in terms of performance, the clusters they detect, and their ability to locate clusters in subspaces. This work introduces a novel algorithm called Click, which finds clusters in categorical datasets based on a search method for k-partite maximal cliques. Click is able to detect subspace clusters, and outperforms previous approaches by a factor of two to three. It scales better than any of the existing method for high dimensional datasets. These results are demonstrated in a comprehensive performance study on synthetic and real data sets.
Phosphorylated Histone H2AX in Spheroids, Tumors, and Tissues of Mice Exposed to Etoposide and 3-Amino-1,2,4-Benzotriazine-1,3-Dioxide

We reported recently that exposure of hamster V79 fibroblasts to 6 drugs that varied in their ability to produce DNA double-strand breaks stimulated formation of phosphorylated histone H2AX (serine 139 phosphorylated histone H2AX; γH2AX). Using flow cytometry to analyze γH2AX antibody-stained cells 1 h after a 30-min drug treatment, the fraction of cells that showed the control levels of γH2AX correlated well with the fraction of cells that survived to form colonies. This observation is now extended to V79 and SiHa human cervical carcinoma cells grown as multicell spheroids and SiHa xenografts and SCCVII tumors in mice. Animals were injected with etoposide, a topoisomerase-II inhibitor that targets proliferating cells or 3-amino-1,2,4-benzotriazine-1,3-dioxide (tirapazamine), a bioreductive cytotoxin that targets hypoxic cells. For spheroids, γH2AX intensity predicted clonogenic cell survival for cells recovered 90 min after drug injection, regardless of position of the cells within the spheroid. Similar results were obtained for etoposide in tumors; however, the γH2AX signal for tirapazamine was smaller than expected for the observed amount of cell killing. Frozen sections of tumors confirmed the greater intensity of γH2AX staining in cells close to blood vessels of tumors soon after treatment with etoposide and the opposite pattern for tumors exposed to tirapazamine. Analysis of cells or frozen sections from mouse spleen and kidney suggests that information can also be obtained on initial damage in normal tissues. These results support the possibility of using γH2AX antibody staining as a method to aid in prediction of tumor and normal tissue response to treatment.
Brauer algebras, symplectic Schur algebras and Schur-Weyl duality

In this paper we prove the Schur-Weyl duality between the symplectic group and the Brauer algebra over an arbitrary infinite field K. We show that the natural homomorphism from the Brauer algebra B n (-2m) to the endomorphism algebra of the tensor space (K 2m )⊗ n as a module over the symplectic similitude group GSp 2m (K) (or equivalently, as a module over the symplectic group Sp 2m (K)) is always surjective. Another surjectivity, that of the natural homomorphism from the group algebra for GSp 2m (K) to the endomorphism algebra of (K 2m )⊗ n as a module over B n (-2m), is derived as an easy consequence of S. Oehms's results [S. Oehms, J. Algebra (1) 244 (2001), 19-44].
Practice Guidelines for the Treatment of Acute Uncomplicated Cystitis and Pyelonephritis in Women : A 2010 Update by the Infectious Diseases Society of America and the European Society for Microbiology and Infectious Diseases

Kalpana Gupta,1 Thomas M. Hooton,2 Kurt G. Naber,9 Björn Wullt,10 Richard Colgan,3 Loren G. Miller,4 Gregory J. Moran,5 Lindsay E. Nicolle,8 Raul Raz,11 Anthony J. Schaeffer,6 and David E. Soper7 1Department of Medicine, Veterans Affairs Boston Health Care System and Boston University School of Medicine, Boston, Massachusetts; 2Department of Medicine, University of Miami Miller School of Medicine, University of Miami, Miami Florida; 3Department of Family and Community Medicine, University of Maryland, Baltimore, Maryland, 4Division of Infectious Diseases, Harbor-UCLA Medical Center, Torrance, and 5Department of Emergency Medicine and Division of Infectious Diseases Olive View-UCLA Medical Center, Slymar, California; 6Deptartment of urology, Northwestern University, Chicago, Illinois; and 7Departments of Obstetrics and Gynecology and Medicine, Medical University of South Carolina, Charleston, South Carolina; 8Department of Internal Medicine and Department of Medical Mirobiology University of Manitoba, Winnipeg, Canada; 9Technical University of Munich, Munich, Germany; 10Lund University Hospital, Lund, Sweden; and 11Infectious Diseases Unit, Ha'Emek Medical Center, Afula, and Rappaport Faculty of Medicine, Technion, Haifa, Israel
RIDE: Mixed-mode control for mobile robot teams

There is a growing need for robot control interfaces that allow a single user to effectively control more than one remote robot. The increasing levels of autonomy demonstrated by our robots allow them to be controlled at higher and higher levels of abstraction. However, these systems are not perfect, and human intervention is sometimes required when unexpected circumstances arise, or an object beyond the capability of the perception systems must be analyzed. This requirement for occasional intervention suggests that our interfaces should be capable of both high-level (taskbased) and low-level (direct teleoperation) control of remote robots, with the ability to switch easily between these modes, as required by the situation. The goal of a single operator controlling many robots also suggests that a system that allows an individual to alert the operator when help is needed would be useful. If there are too many robots for the operator to attend to at once, there is a distinct possibility that a robot may sit idle, waiting for help, for a long time without such a notification system.
Towards Full Automation of Lexicon Construction

We describe work in progress aimed at developing methods for automatically constructing a lexicon using only statistical data derived from analysis of corpora, a problem we call lexical optimization. Specifically, we use statistical methods alone to obtain information equivalent to syntactic categories, and to discover the semantically meaningful units of text, which may be multi-word units or polysemous terms-in-context. Our guiding principle is to employ a notion of "meaningfulness" that can be quantified information-theoretically, so that plausible variants of a lexicon can be judged relative to each other. We describe a technique of this nature called information theoretic co-clustering and give results of a series of experiments built around it that demonstrate the main ingredients of lexical optimization. We conclude by describing our plans for further improvements, and for applying the same mathematical principles to other problems in natural language processing.
The novel Y371D myocilin mutation causes an aggressive form of juvenile open-angle glaucoma in a Caucasian family from the Middle-East

Purpose To search for the genetic cause of juvenile open-angle glaucoma (JOAG) in a Caucasian family and to perform genotype/phenotype correlation studies in the kindred. Methods Six members of a three-generation family originating from Uzbekistan and now living in the Middle East were recruited from one large clinic in Israel. Ophthalmologic investigations comprised of visual field assessments, intraocular pressure measurements, optic disc evaluation, and gonioscopy. Medical charts were obtained to date the onset of glaucoma and to evaluate aggressivity of the trait. We screened the myocilin gene (MYOC, OMIM 601652) by direct genomic sequencing of its three exons in all family members. Results JOAG segregated as an autosomal dominant trait in four members of the family. The proband, a 14-year-old girl, had been diagnosed with juvenile open-angle glaucoma at 12 years old. Her mother, maternal aunt, and maternal grandfather all had JOAG that started at an early age. The disorder progressed rapidly even under optimal medical treatment, and all four patients had to undergo trabeculectomy. One missense mutation, Y371D (1111t→g, Tyr [Y] 371 Asp [D]), was identified. This mutation cosegregated with the disorder in all affected members and was absent in 200 Caucasian controls. The Y371D MYOC mutation has not been reported before. One cousin of the proband was a silent heterozygotic carrier of the mutation and was still asymptomatic at nine years of age. Conclusions We identified a novel mutation (Y371D) in MYOC from a Caucasian family who presented with an aggressive form of JOAG that required early trabeculectomy. Genetic screening of the MYOC mutation was beneficial in predicting one asymptomatic heterozygotic carrier.
Community-Associated Methicillin-Resistant Staphylococcus aureus and Athletes

Abstract The remarkable ability of Staphylococcus aureus to develop antibiotic resistance in conjunction with the emergence of highly virulent and/or transmissible strains has established the pathogen as a leading cause of human bacterial infections worldwide. Historically, methicillin-resistant S aureus (MRSA) was found almost exclusively in hospitals and/or health care-related facilities. However, in the late 1990s, community-associated MRSA strains emerged in the United States and rapidly became the leading cause of community-associated bacterial infections. An enhanced understanding of the pathogenesis and epidemiology of this bacterium is fundamental for the prevention and/or treatment of community-associated MRSA infections. This review highlights salient features of S aureus biology that contribute to the exceptional ability of this pathogen to cause human disease, as well as discusses, in brief, the established approaches for treatment and prevention of infection.
CONTINUOUS SOIL MOISTURE MAPPING USING MODIS NDVI AND LST PRODUCTS

Soil moisture is an important storage pool in the hydrologic cycle. The water content of soil affects a variety of physical and biological processes in the biosphere and links the Earth's surface and atmosphere through its influence on surface energy and moisture fluxes. In addition, antecedent soil moisture conditions affect the hydrologic behavior of land surfaces by controlling, in part, the infiltration capacity of soils and the partioning of precipitation into runoff and storage terms (Ward, 1967). Because of this, quantified soil moisture conditions are critical inputs for models in agriculture, biology, climatology, hydrology, and meteorology.
Forty years of ceramic-on-ceramic THR bearings

Abstract The evolution of ceramic bearings for Total Hip Joint Replacement (THR), which have now been in clinical use for over 40 years, is reviewed from a historical perspective with emphasis on the characteristics of the composite materials in clinical use today, their mechanical properties, and wear behavior. Evidence is provided about the advantage of today’s composite ceramics over those of previous generations in terms of increased reliability and minimum wear, especially in the case of bearings operating under abnormal conditions (edge loading and microseparation).
Does the Source of Capital Affect Capital Structure?

Empirical examinations of capital structure have led some to conclude that firms are under-levered. Implicit in this argument and much of the empirical work on leverage is the assumption that the availability of incremental capital depends solely on the risk of the firm's cash flows and characteristics of the firm. However, the same market frictions that make capital structure relevant suggest that firms may be rationed by lenders, leading some firms to appear to be under-levered relative to unconstrained firms. We examine this theory, arguing that the same characteristics that may be associated with firms being rationed by the debt markets are also associated with financial intermediaries, opposed to bond markets, being the source of a firm's debt capital. We find that firms have significantly different leverage ratios based on whether they have access to public bond markets as measured by the firm having a debt rating. Although firms with a debt rating are fundamentally different, these differences do not explain our findings. Even after controlling for the firm characteristics previously found to determine observed capital structure and the possible endogeneity of having a bond rating, we find that firms which are able to raise debt from public markets have 40 percent more debt.