Miracle-dz/UniFAR-FTUs huggingface dataset:
Identification and Analysis of a Four-Gene Set for Diagnosing SFTS Virus Infection Based on Machine Learning Methods and Its Association with Immune Cell Infiltration

Severe Fever with thrombocytopenia syndrome (SFTS) is a highly fatal viral infectious disease that poses a significant threat to public health. Currently, the phase and pathogenesis of SFTS are not well understood, and there are no specific vaccines or effective treatment available. Therefore, it is crucial to identify biomarkers for diagnosing acute SFTS, which has a high mortality rate. In this study, we conducted differentially expressed genes (DEGs) analysis and WGCNA module analysis on the GSE144358 dataset, comparing the acute phase of SFTSV-infected patients with healthy individuals. Through the LASSO–Cox and random forest algorithms, a total of 2128 genes were analyzed, leading to the identification of four genes: ADIPOR1, CENPO, E2F2, and H2AC17. The GSEA analysis of these four genes demonstrated a significant correlation with immune cell function and cell cycle, aligning with the functional enrichment findings of DEGs. Furthermore, we also utilized CIBERSORT to analyze the immune cell infiltration and its correlation with characteristic genes. The results indicate that the combination of ADIPOR1, CENPO, E2F2, and H2AC17 genes has the potential as characteristic genes for diagnosing and studying the acute phase of SFTS virus (SFTSV) infection.
Mapping of Impervious Surface using Spectral Angle Mapper (SAM) and NDVI Techniques, Case Study: Bhopal City

Impervious surface is essential to plot urban area development and the distribution of impervious surfaces can be used as a tool in environmental applications. Multispectral remote sensing based mapping has shown great potential in detailing land uses. Eastern area of Bhopal city has been analyzed of land use/land cover and it is derived from the results that some parts of land which has potentiality for agriculture has been gradually converted to urban plots leading to reduction of land for growing crops whereas some other areas, which tend to be impervious are left bare and it is a crucial fact that no agriculture is possible in such surfaces. Hence proper analysis regarding the surface area has to be done before executing development strategies. This paper emphasiseson the parts of land in the concerned area, that can be utilized for urban development. For comparison, four types of Endmember fractions (i.e. soil, vegetation, water and imperviousness) were used in this study. Selection of Endmember fraction was done by MNF, NDWI and NDVI. Spectral Angle Mapper (SAM), a classification technique, was used to map impervious surface using land sat data of the proposed area of study. SAM classification resulted in classifiying the study area into 5 landclass types with total imperviousness cover of about 27% of the area studied.
Attempts to locate and sample the white shark, Carcharodon carcharias (Lamniformes: Lamnidae), along the Italian coasts in the Mediterranean Sea

Described in the present report are documented attempts to tag and sample the white shark, Carcharodon carcharias (Linnaeus, 1758), along Italian coasts in the Mediterranean Sea, which took place near the Lampedusa Island in the lower Tyrrhenian Channel of Sicily, off the coast of Rimini in the Adriatic Sea, and of Civitavecchia in the central Tyrrhenian Sea. The project, activated in 2015, was aimed at tagging and sampling specimens of the white shark in order to collect data useful to implement conservation strategies in the Mediterranean Sea. Despite four tagging attempts made in 2017, 2018, 2021, and 2022 with 288 total hours of baiting activity and the use of 1030 kg of chum, no white sharks or any other shark species were sighted.
The northward shift of Weihe River and the uplift of Qinling Mountains

As the Weihe River graben subsided constantly,this graben basin had accepted a huge of Cenozoic deposits.The very top part of these deposits,including a little of the Upper Pleistocene and the main part of the Holocene,was exposed at many sites of Weihe River second terrace.The exposed stratigraphic section of the Upper Pleistocene and the Holocene at Qilipu village, near Xianyang City,is about 15m thick.According to the characteristics of the rocks,it has been subdivided into nine strata ranging from the top as 1 to the bottom as 9.Five samples used for age dating by 14C and accelerator were collected.Sample S1 is from the lower part of the third stratum; S2,in the middle of the fifth;S3,at the bottom of the sixth; S4, at the lower part of the eighth and S5,just at the bottom line of the eighth. The ages of these samples are 3 160±80(or±55) B.P. for S1, 4 370±50B.P.for S2,10 200±1 00B.P.for S3,17 025±170B.P. for S4, 18 600±145B.P. for S5, respectively.The sedimentary rate of each deposited body has been measured on the basis of the age of the sample and the thickness of deposit between two adjacent samples.These sedimentary rates obviously show a tendency that the newer the geologic period,the faster the sedimentary rate,especially in the Holocene.Considering the uplift of Qinling Mountains,there is a trend that the newer the geologic period,the faster the uplift rate.Because the Weihe River is situated at the north of Qinling Mountains,the two trends might have some interrelationship.During the uplift process of Qinling Mountains,more eroded materials were accumulated in the graben basin,which push the Weihe River towards the north. Although many other factors make the Weihe River shift northwards,we think the essential and main reason is the uplift of Qinling Mountains. 
Policy Study of Local Content Curriculum in Madrasah

The local curriculum that is part of the national curriculum has educational programs. One of the elements that must be maintained and maintained through educational activities is the values, traditions, culture, skills, and concepts prevailing in society. In recent years, the government implemented curriculum changes by adding local subjects. Through learning local subjects, it is expected that students will not only have academic knowledge that is global as expected but also have concern for social and cultural values that surround students. Researchers use the literature study method, which is a method of collecting data by understanding and studying theories from various literature related to the research. There are four stages of literature study in this research, namely preparing the necessary equipment, compiling a bibliography, managing time, and reading or recording research material. Conceptually, the locally-based curriculum consists of two forms. The first form is inherent in all subjects, and the second form is a separate activity that is not related to the subject. This paper tries to explain the model and implementation of a locally-based curriculum in Madrasah
DISTRICT HEATING SYSTEMS IN ORADEA, ROMANIA

Oradea is located on the Crisul Repede River, in the northwestern corner of Romania almost due west of Budapest, Hungary. The city has a population around half a million people and can trace its origins back to the Neolithic Age. It was an urban settlement beginning in the 13th century and has been an economic and cultural center for the region. It is a geothermal city with 12 wells drilled within the city limits, six in the nearby Felix Spa and five in the Bors geothermal area to the west, with one doublet set at Nufarul. Currently, there are a variety of geothermal uses in the area, including space and greenhouse heating, domestic hot water supply, process heat, balneology and swimming pools. Wellhead temperatures range from 70 to 105{degrees}C with artesian flows of from 5 to 25 L/s. The present installed capacity is 25 MWt and the heat supply is estimated at 60,000 MWh per year (216,000 GJ/yr). With pumping, the production would double and adding four more doublets, the installed capacity be increased to 65 MWt.
Finite‐difference elastic wave propagation in 2D heterogeneous transversely isotropic media1

The velocity-stress formulation for propagation of elastic seismic waves through 2D heterogeneous transversely isotropic media of arbitrary orientation is presented. The equations are recast into a finite-difference scheme and solved numerically using fourth-order spatial operators and a second-order temporal operator on a staggered grid. Absorbing, free-surface and symmetry boundary conditions have been implemented. Test cases compare well with other published solutions. Synthetic seismograms are calculated over two idealized models: (i) vertical fractures in granite with a dolerite sill reflector and (ii) a dipping anisotropic shale. Comparisons with the isotropic counterparts show significant differences which may have to be accounted for in seismic processing in the future.
The strength of correlations between geotechnical variables and acoustic classifications

Seabed grain size, shear strength, bearing strength, and porosity were measured at 15 sites, all in bays and harbours around southern Vancouver Island. Sounder echoes at 38 and 200 kHz from the same sites were classified using the QTC VIEW/sup TM/ technology. This approach uses a feature set generated from the direct echoes by a set of algorithms and then reduced by multivariate analysis, with similar acoustic responses put into the same class. Canonical correlation analysis was used to uncover correlations between two data sets: the frequency of occurrence of each acoustic class, and the four geotechnical variables. Bearing strength was found to be the major contributor to the first geotechnical canonical variable, which correlated with classes from the 38-kHz echoes with a coefficient of 0.94.
The mycoparasite Pythium oligandrum induces legume pathogen resistance and shapes rhizosphere microbiota without impacting mutualistic interactions

Pythium oligandrum is a soil-borne oomycete associated with rhizosphere and root tissues. Its ability to enhance plant growth, stimulate plant immunity and parasitize fungal and oomycete preys has led to the development of agricultural biocontrol products. Meanwhile, the effect of P. oligandrum on mutualistic interactions and more generally on root microbial communities has not been investigated. Here, we developed a biological system comprising P. oligandrum interacting with two legume plants, Medicago truncatula and Pisum sativum. P. oligandrum activity was investigated at the transcriptomics level through an RNAseq approach, metabolomics and finally metagenomics to investigate the impact of P. oligandrum on root microbiota. We found that P. oligandrum promotes plant growth in these two species and protects them against infection by the oomycete Aphanomyces euteiches, a devastating legume root pathogen. In addition, P. oligandrum up-regulated more than 1000 genes in M. truncatula roots including genes involved in plant defense and notably in the biosynthesis of antimicrobial compounds and validated the enhanced production of M. truncatula phytoalexins, medicarpin and formononetin. Despite this activation of plant immunity, we found that root colonization by P. oligandrum did not impaired symbiotic interactions, promoting the formation of large and multilobed symbiotic nodules with Ensifer meliloti and did not negatively affect the formation of arbuscular mycorrhizal symbiosis. Finally, metagenomic analyses showed the oomycete modifies the composition of fungal and bacterial communities. Together, our results provide novel insights regarding the involvement of P. oligandrum in the functioning of plant root microbiota.
Existence and stability of ground-state solutions of a Schrödinger—KdV system

We consider the coupled Schrödinger–Korteweg–de Vries system which arises in various physical contexts as a model for the interaction of long and short nonlinear waves. Ground states of the system are, by definition, minimizers of the energy functional subject to constraints on conserved functionals associated with symmetries of the system. In particular, ground states have a simple time dependence because they propagate via those symmetries. For a range of values of the parameters α, β, γ, δi, ci, we prove the existence and stability of a two-parameter family of ground states associated with a two-parameter family of symmetries.
τ‐migration and velocity analysis: application to data from the Red Sea

Imaging pre‐salt reflections for data acquired from the coastal region of the Red Sea is a task that requires prestack migration velocity analysis. Conventional post‐stack time processing lacks the lateral inhomogeneity capability, necessary for such a problem. Prestack migration velocity analysis in the vertical time domain reduces the velocity–depth ambiguity that usually hampers the performance of prestack depth‐migration velocity analysis. In prestack τ‐migration velocity analysis, the interval velocity model and the output images are defined in τ (i.e. vertical time). As a result, we avoid placing reflectors at erroneous depths during the velocity analysis process and thus avoid inaccurately altering the shape of the velocity model, which in turn speeds up the convergence to the true model. Using a 1D velocity update scheme, the prestack τ‐migration velocity analysis produces good images of data from the Midyan region of the Red Sea. For the first seismic line from this region, only three prestack τ‐migration velocity analysis iterations were required to focus pre‐salt reflections in τ. However, the second line, which crosses the first line, is slightly more complicated and thus required five iterations to reach the final, reasonably focused, τ‐image. After mapping the images for the two crossing lines to depth, using the final velocity models, the placements of reflectors in the two 2D lines were consistent at their crossing point. Some errors occurred due to the influence of out‐of‐plane reflections on 2D imaging. However, such errors are identifiable and are generally small.
Human-Robot Collaboration in a Sanding Task

Robots can help reduce physical stress in manual sanding, but implementation has been challenging due to the skill required, task variability, and robot limitations. In shared control (SC) a robot operates semi-autonomously while the human provides real-time corrections. A laboratory study tested the effectiveness of SC for removing paint using an orbital sander. A robot autonomously sanded the surface, and twenty participants sanded manually and in collaboration with a robot using SC. Subjective discomfort for manual sanding was greater than SC in the upper arm by 28.5%, the lower arm by 29%, the hand by 38%, and the shoulder by 42%. Muscle fatigue, measured using EMG, was 22.4% greater for the manual condition. Cognitive workload measured using the NASA TLX was 14.25% more for manual sanding. Digital imaging showed that SC outperformed the fully autonomous robot by 10.75% for uniformity, by 4.96% for quantity, and by 6.06% for average performance.
Efficient estimation for the proportional hazards model with left‐truncated and interval‐censored data

Interval‐censored data often arise in prospective studies involving periodical follow‐up for monitoring the failure event occurrence. In addition to censoring, left truncation also occurs if only participants who have not experienced the failure event are enrolled in the study, which clearly induces the selection bias and makes the analysis more complicated. This work provides an efficient maximum likelihood estimation approach that appropriately adjusts the biased sampling for the proportional hazards model with left‐truncated and interval‐censored data. A flexible and stable expectation–maximisation algorithm via a two‐stage data augmentation is developed to maximise the intractable likelihood function. The asymptotic properties of the proposed estimators are established with the empirical process theory. The numerical results obtained from extensive simulations suggest that the proposed method performs satisfactorily and has some prominent advantages over the competing methods. An application to a colon cancer dataset also demonstrates the usefulness of the proposed method.
HYPHOP: a tool for high-altitude, long-range monitoring of hydrogen peroxide and higher organic peroxides in the atmosphere

Abstract. Measurements of hydroperoxides help improve our understanding of atmospheric oxidation processes. Here, we introduce an instrument setup designed for airborne hydroperoxide measurements. The HYdrogen Peroxide and Higher Organic Peroxides (HYPHOP) monitor has been deployed on the German High-Altitude and Long-range Observatory (HALO) aircraft and is based on dual-enzyme fluorescence spectroscopy, enabling measurements up to an ambient pressure of approximately 150 hPa pressure altitude (13.5–14 km). We characterized the measurement method and data acquisition of HYPHOP with special emphasis on potential sources of interference impacting instrument uncertainty. Physically derived interference was examined based on a dedicated test flight to investigate potential measurement inconsistencies arising from the dynamic movement patterns of the aircraft. During the test flight, the hydroperoxide monitor was operated in the background air sampling mode with purified air by scrubbing atmospheric trace gases, to investigate the instrument stability and potential parameters that might affect the measurements. We show that technical and physical challenges during flight maneuvers do not critically impact the instrument performance and the absolute measurements of hydroperoxide levels. Dynamic processes such as convective transport in the South Atlantic Convergence Zone (SACZ) are well-resolved as shown in the overview of a recent measurement campaign, Chemistry of the Atmosphere: Field Experiment in Brazil, in December 2022–January 2023 (CAFE-Brazil). The instrument precision based on the measurement results during CAFE-Brazil for hydrogen peroxide and the sum of organic hydroperoxides is estimated to be 6.4 % (at 5.7 ppbv) and 3.6 % (at 5.8 ppbv), respectively, and the corresponding detection limits 20 and 19 pptv for a data acquisition frequency of 1 Hz. The determined instrumental temporal resolution is given at approximately 120 s.
Origin of the Moon and Lunar Water

Three principal concepts regarding lunar formation have been examined: the accretion hypothesis, the mega-impact theory, and the multi-impact model. The multi-impact model amalgamates the salient facets of the mega-impact theory and the accretion hypothesis. As per this model, fragments of the terrestrial crust are ejected into space during collisions with numerous planetesimals (proto-asteroids) with diameters around 10-100 kilometers. In the vicinity of Earth’s orbit, this ejecta interacts with the accretion disk, augmenting its mass. Numerical computations demonstrate that particles within the prograde-rotating accretion disk effectively capture prograde-rotating ejecta while shedding retrograde-rotating ejecta onto the planetary body. The multi-impact theory provides an explanation for the creation of not just the Moon and Charon but also the satellites of asteroids. Several predictions regarding the parameters of asteroid satellites posited by this theory have already been validated through statistical analysis of binary asteroids. Different models of lunar formation yield varied conclusions regarding the quantity of lunar water, its subsurface distribution, and isotopic composition. The mega-impact theory postulates the genesis of a largely desiccated Moon. Consequently, the modest lunar water content may arise from comets, solar wind, or the transport of water from Earth’s atmosphere. These mechanisms for lunar water formation imply its superficial occurrence in polar regions and substantial deviation of the deuterium-to-hydrogen (D/H) ratio from terrestrial norms. Conversely, the multi-impact theory posits lunar water’s origin from planetesimals, akin to terrestrial water. Thus, a significant quantity of lunar water is inferred, expected to be pervasive across the lunar surface at varying depths, and possessing isotopic composition analogous to terrestrial water. Geomorphological structures in the lunar polar regions (smoothed craters, landslides, regular patterns) suggest the presence of a substantial permafrost layer with an approximate thickness of a kilometer.
Quantitative potentials for rainwater handling using the “Three Points Approach” (3PA)

Rainwater in cities is both a resource for e.g. recreational and amenity purposes and a potential problem due to e.g. pluvial flooding. This study provides a new tool to communicate the potentials for alternative rainwater handling taking into account the properties of rainfall making it both a problem and a resource. The quantitative potentials of alternative rainwater handling are calculated in relation to the total precipitation volume, the total supplied potable water volume and the total volume of wastewater treated. Two different cases are investigated: one where rainwater is infiltrated and one where it is harvested and used for toilet flushing. The potential is calculated for the two largest municipalities of Denmark: Copenhagen and Aarhus. The Three Points Approach is used to distinguish between different rain domains, and to subdivide the quantitative potentials accordingly. This analysis shows that designing alternative rainwater handling systems for larger return periods than 5 to 10 years result in a very marginal increase in rainwater volume handled by these systems compared to systems designed for less severe events
Self-Talk Scale: Further validation and Polish adaptation

: The aim of the article is twofold: to introduce a Polish adaptation of the Self-Talk Scale (STS) by Brinthaupt et al. (2009), including psychometric properties of the method, and to present some empirical results focusing on relationships between inner speech and other variables, like temperamental and personality traits, selected features of characteristic adaptations, and the self. In a Polish sample of 1,321 participants (770 women) aged 18–70 years ( M = 26.62, SD = 8.30), the internal structure of the scale consisting of self-criticism, self-reinforcement, self-management, and social assessment was confirmed with confirmatory factor analysis (CFA), which showed an acceptable fit of the four-function model to the empirical data. However, according to EFA, two functions, self-management and social assessment, constituted one common factor. Internal consistency of the total score was high, α = . 87 and . 88, in two samples, as well as for particular functions, from . 73 to . 85. Validity of the STS was confirmed with the Internal Dialogical Activity Scale – Revised (Oleś et al., 2020). Moreover, STS results corresponded with traits like endurance and neuroticism; characteristic adaptation, like love for life; characteristics of the self, like reflection and rumination; and slightly with tolerance for ambiguity.
Action leadership

Abstract: Given the economic and social reality that MSMEs are experiencing in the post-pandemic world, it is necessary to have a new style of leaders who can solve new organizational problems, for which a new leadership model was generated that integrates previous theories. Three independent leadership theories were mixed to develop a multidimensional model that could facilitate a better leadership assessment aiming to analyze the most important characteristics that employees seek in a leader. Data from 384 MSMEs employees was collected to analyze 31 combined items from three instruments to assess transformational, authentic, and learning leadership. This data was analyzed for validity using exploratory and confirmatory factor analyzes, resulting in a new model that could help researchers to collect reliable data that could be analyzed using the lens of this new model that receives the name of "action leadership". This new multidimensional model will facilitate the development of better working environments in MSMEs, guiding the efforts of their leaders to be able to fulfil the needs of their employees and their expectations about how their leaders solve the challenges. Keywords: Action Leadership; Transformational leadership; MSME´s JEL codes: M10, M12