Miracle-dz/UniFAR-FTUs huggingface dataset:
An Adaptive Receiver for STBC in Frequency Selective Channel with Improved Robustness and Pilot Requirements

Abstract: The semi-blind recursive least squares (RLS) based adaptive receiver has been designed to perform joint interference suppression and equalization for space time block codes (STBC) in a frequency and time selective channel. In order to decrease pilot requirements in the training block, this paper introduces a linear predictor (LP) algorithm to do a forward prediction of the channel coefficients based on a smaller pilot block. We then introduce a QR-decomposition (QRD) based algorithm to improve the performance of the receiver at higher Doppler frequencies. The simulation results show that the addition of the LP does not affect the frame error rate (FER) of the overall system. Linear prediction requires a smaller number of pilot symbols in order to provide the channel estimates for a given burst. Hence the LP increases the overall throughput of the system by decreasing the pilot symbols required. The simulation results show that this is a more effective method for improving the system performance as the overall FER of the combined QRD-LP receiver is decreased significantly. Finally, by comparing the QRD based receiver and the RLS based receiver at higher Doppler frequencies, we verify that the QRD receiver has superior FER performance under these conditions.
Tunable Resonances in the Plasmonic Split-Ring Resonator

A nanoscale resonator composed of two metal-insulator-metal (MIM) waveguides and a split ring is investigated numerically. The multipolar plasmonic resonance modes can be excited, weakened, or even cut off by adjusting the split angle. These novel phenomena are due to the electric polarization in the split area. Odd modes exhibit when the electric field is polarized perpendicular to the split. The resonator acts as a LC circuit for the electric field polarized parallel to the split, in which even modes are excited. The capacitance diminished when the split depth is increased, and the resonance wavelengths of even modes exhibit blue shift. Our results imply an extensive potential for tunable multichannel filters and biosensor devices in integrated nano-optics.
Parent‐of‐origin effects for MSX1 in a Chilean population with nonsyndromic cleft lip/palate

Based on association and sequencing studies, investigators have postulated muscle segment homeobox 1 (MSX1) as a strong candidate gene involved in the causation of nonsyndromic cleft lip with or without cleft palate (NSCLP). Parent‐of‐origin effects have been suggested for some NSCLP candidate genes but not for MSX1. The aims of the present study were to test for allele/haplotype associations applying the transmission disequilibrium test (TDT) and the transmission asymmetry test (TAT) to evaluate the possible parent‐of‐origin effects of MSX1 in Chilean patients with NSCLP. We analyzed five SNPs (rs6446693/c.‐425G>T/c.‐35G>A/rs3775261/rs12532) located from 6.3 kb upstream to 3′ UTR in a sample of 150 unrelated NSCLP case–parent trios. Four haplotypes showed overtransmission from parents to affected progeny, but individual SNPs did not. Two haplotypes presented allele combination C‐G‐A‐G (P = 0.035) and two T‐G‐C‐A (P = 0.044) (SNP order rs6446693/c.‐35G>A/rs3775261/rs12532). The rs12532 A allele had a 2.08‐fold increase in the risk of NSCLP when inherited from the father (95% CI: 1.10–4.02; P = 0.025), but not from the mother. These results could indicate epigenetic control by imprinting in the role of MSX1 in NSCLP. Different authors have proposed that some genes that play a role in NSCLP depend on parental origin. Our findings and those previously reported by our group show that a variety of factors appears to be involved in the association between MSX1 and NSCLP. The full mechanism of MSX1 in the development of NSCLP has not been fully understood. © 2010 Wiley‐Liss, Inc.
A Novel Method for the Parameterization of a Li-Ion Cell Model for EV/HEV Control Applications

This paper presents a Li-ion cell model parameterization technique for hybrid electric and electric vehicle control applications. The proposed method is based on an equivalent electrical circuit (EEC) model of the Li-ion cell and combines the advantages of the two main strategies employed for cell model parameterization, namely, the offline and online procedures. Offline methods are based on the identification of relevant EEC parameter values using a limited set of test data specific to the target cell chemistry. Conversely, online techniques employ adaptive algorithms that update the cell model as it is being used. The novel method presented in this paper employs recurrent offline updates of the EEC parameterization set, and thus, it integrates the advantages of the offline approach, such as flexibility, reduced complexity, and improved run-time performance, with the main benefit of the online counterpart, which is the capacity to adapt the model parameterization to uncharacterized operating conditions. Based on an extensive set of experimental and simulation results obtained from tests specified in the IEC 62660-1 standard, it is shown that the proposed approach offers a significant accuracy improvement over simple offline methods, as well as enhanced runtime speed in comparison with commonly employed online strategies.
Sentiment classification for unlabeled dataset using Doc2Vec with JST

Supervised learning require sentiment labeled corpus for training. But it is hard to apply automatic sentiment classification system to new domain because labeled dataset construction costs a lot of time. Meanwhile, researches using Doc2vec based document representation beat out other sentiment classification researches. However, these document representation methods only represent documents' context or sentiment. In this paper, we proposed supervised learning scheme for unlabeled corpus and also proposed document representation method which can simultaneously represent documents' context and sentiment.
Health Literacy—Identification and Response

The term ‘‘health literacy’’ has now permeated the public health lexicon. The 2006 U.S. National Assessment of Adult Literacy (NAAL) is the first national survey to employ assessment tasks conducted specifically to measure the health literacy of adults living in the United States. These landmark data provide results on the scope of overall literacy and health literacy in America with a survey of over 19,000 U.S. adults. The health literacy scale and health literacy tasks were guided by the definition of health literacy accepted by the U.S. Institute of Medicine and Healthy People 2010 that states that health literacy is: ‘‘The degree to which individuals have the capacity to obtain, process, and understand basic health information and services needed to make appropriate health decisions (HHS, 2000; Ratzan & Parker, 2000; Institute of Medicine, 2004). Similarly, across the Atlantic, the UK government also embraced the U.S. definition. The UK Committee on Safety of Medicines highlighted this concept is a useful tool in identifying problems in communicating health information and enabling people to use that information to make health decisions. They further emphasized a component they called medication literacy, referring to the range of skills needed to access, understand and act on medicines information (Medicines and Healthcare Products Regulatory Agency, 2005). The most recent U.S. study employed a scale of 0 to 500 for overall literacy and for health literacy, and categorized skills in four performance levels: Below Basic, Basic, Intermediate, and Proficient. Official reports of the health literacy survey emphasized that the majority of adults (53%) had Intermediate health literacy. About 22% had Basic and 14% had Below Basic health literacy. The complete report is available at http:==nces.ed.gov=pubs2006=2006483.pdf. Additionally, adults in the oldest age group—65 and older—had lower average health literacy than adults in younger age groups. Adults ages 25 to 39 had higher average health literacy than adults in other age groups.
A DNA vaccine encoding mutated HPV58 mE6E7-Fc-GPI fusion antigen and GM-CSF and B7.1

Background Persistent infection with high-risk human papillomavirus (HPV) is a predominant cause of cervical cancer, and HPV58 is the third most common virus detected in the patients with cervical cancer in Asia. E6 and E7 are the viral oncogenes which are constitutively expressed in HPV-associated tumor cells and can be used as target antigens for related immunotherapy. In this study, we modified the HPV58 E6 and E7 oncogenes to eliminate their oncogenic potential and constructed a recombinant DNA vaccine that coexpresses the sig-HPV58 mE6E7-Fc-GPI fusion antigen in addition to granulocyte-macrophage colony-stimulating factor (GM-CSF) and B7.1 as molecular adjuvants (PVAX1-HPV58 mE6E7FcGB) for the treatment of HPV58 (+) cancer. Methods PVAX1-HPV58 mE6E7FcGB recombinant DNA vaccine was constructed to express a fusion protein containing a signal peptide, a modified HPV58 mE6E7 gene, and human IgG Fc and glycosylphosphatidylinositol (GPI)-anchoring sequences using the modified DNA vaccine vector PVAX1-IRES-GM/B7.1 that coexpresses GM-CSF, and B7.1. C57BL/6 mice were challenged by HPV58 E6E7-expressing B16-HPV58 E6E7 cells, followed by immunization by PVAX1-HPV58 mE6E7FcGB vaccine on days 7, 14, 21 after tumor challenge. The cellular immune responses in immunized mice were assessed by measuring IFN-γ production in splenocytes upon stimulation by HPV58 E6E7-GST protein and the lysis of B16-HPV58 E6E7 target cells by splenocytes after restimulation with HPV58 E6E7-GST protein. The antitumor efficacy was evaluated by monitoring the growth of the tumor. Results PVAX1-HPV58 mE6E7FcGB elicited varying levels of IFN-lsgdB58onn T-cell immune responses and lysis of target cell in mice in response to the recombinant antigen HPV58 E6E7-GST. Furthermore, the vaccine also induced antitumor responses in the HPV58 (+) B16-HPV58 E6E7 tumor challenge model as evidenced by delayed tumor development. Conclusion The recombinant DNA vaccine PVAX1-HPV58 mE6E7FcGB efficiently generates cellular immunity and antitumor efficacy in immunized mice. These data provide a basis for the further study of this recombinant vaccine as a potential candidate vaccine.
Hospital-acquired acute renal failure.

Acute renal failure (ARF) is the abrupt loss of renal function sufficient to decrease urinary elimination of nitrogenous waste (urea nitrogen and creatinine). Although there is consensus about this general definition, few agree on the magnitude of the rise in serum eneatinine necessary to ascribe a diagnosis of ARF (1,2). These differences in definition plus variances in methods of patient accrual, populations analyzed, and eategorization of causes render development of a broad-based overview of ARF difficult. However. two generalizations about contemporary ARF are compelling. First, ARF is predominantly a hospital-acquired disorder (1-3). Second, the high mortality of patients with ARF is not explained entirely by comonbid conditions. Recent data indicate that ARF per se increases the risk of development of multiple nonrenal conditions that lead to death and disability (4). Thus, ARF should not always be considered a treatable condition that complicates advanced disease. Together, these two generalizations prompt this review, which focuses on the causes, diagnosis, prevention, and management of hospital-acquired ARF.
Historical Background

According to a centuries-old European legend, children that tasted salty when kissed on the forehead were considered " enchanted " or " be-witched " and would soon die. The first references to possible carriers of the disease appeared in the literature in the 16 th century, as autopsy reports. The first records of an autopsy performed on a " cursed " 11-year-old girl who presumably died of cystic fibrosis was performed in 1595 by Pi-eter Pauw, professor of Botany and Anatomy in Leiden, Netherlands, and included the first medical description of the related pancreatic lesions 1. In 1606, Alonso y de los Ruyzes de Fonteca, professor of medicine in Henares, Spain, reported that one's fingers tasted salty after rubbing the forehead of these supposedly bewitched children 1. Nearly three centuries later, in 1905, Land-steiner described meconium ileus, relating it to exocrine pancreatic insufficiency. Three decades later, Fanconi (1936) referred to the disease as cystic fibromatosis with bronchiectases and recognized it as a disease entity independent of celiac disease 1. At the same time, Dorothy An-dersen, in 1938, described the disease in minute detail, with its clinical, anatomopathological, and epidemiological characteristics, referring to it as " cystic fibrosis of the pancreas " 1. In mid-1945, Farber believed that the cause of the disease was a generalized " state of thickening of secretions " , thus coining the term mu-Abstract The clinical and diagnostic aspects of cystic fibro-sis have been extensively reviewed, with an emphasis on neonatal screening. This systematic literature review involved a search for relevant contributions in the PubMed and SciELO databases. The first references to cystic fibrosis date to the Middle Ages. Cystic fibrosis is the most frequent autosomal recessive hereditary disease among Caucasians (1:2,000 to 3,500). More than 1,000 mutations lead to the disease, the most common being ΔF508, with 70% prevalence among Cana-dian, Northern European, and American Cauca-sians and 23 to 55% prevalence among Brazil-ians. The basic defect is in chloride ion secretion. Cystic fibrosis screening has long been controversial , and after almost three decades, there are few nationwide programs (most are regional or local). However, the U.S. Centers for Disease Control and Prevention (CDC) has concluded that screening for cystic fibrosis is justified. The lack of a specific screening test and the ethnic heteroge-neity of the Brazilian population pose challenges for neonatal screening. Cystic fi brosis and neonatal screening Fibrose cística e a triagem neonatal …
Benchmarks for the Assessment of Novel Cardiovascular Biomarkers

The investigation of novel circulating serum and plasma biomarkers in patients with cardiovascular disease has been accelerating at a remarkable pace. For example, a Medline search that uses the terms “biomarkers” and “acute coronary syndromes” (ACS) reveals an approximate tripling in the number of published reports during the 2-year interval from 2003 to 2004 compared with the period from 2001 to 2002, and this number more than doubled from 2005 to 2006. Although this expanding body of research has established firm evidence for the value of biomarkers, such as for diagnosis and risk assessment among patients with suspected ACS,1 it has also deluged the clinical and research communities with candidate biomarkers, very few of which are likely to survive the test of time as useful clinical tools.2,3 It is thus increasingly important for researchers, manufacturers, regulators, and clinicians to critically appraise the value of new biomarkers as they emerge as candidates for further investigation and possible clinical application. The superb report by Wollert and colleagues4 in the present issue of Circulation on growth differentiation factor-15 (GDF-15) as a biomarker for prognostic assessment in ACS provides an opportunity to outline a basic set of benchmarks against which new markers can be evaluated. Article p 962 Assessment of the clinical potential of a novel biomarker5 may be structured around 3 fundamental questions (Figure): (1) Can the clinician measure it? (2) Does it add new information? (3) Does it help the clinician to manage patients? A, Criteria for assessment of novel cardiovascular biomarkers for clinical use. Statements in bold font are given the highest priority. B, Clinical applications of cardiovascular biomarkers. To be clinically useful, analytical methods must be available that allow reliable measurement, optimally with capability for high throughput tests, prompt turnaround time, and reasonable cost. Evaluation of …
Restless legs syndrome prevalence and impact: REST general population study.

BACKGROUND Restless legs syndrome (RLS), a common sensorimotor disorder, has a wide range of severity from merely annoying to affecting sleep and quality of life severely enough to warrant medical treatment. Previous epidemiological studies, however, have failed to determine the prevalence of those with clinically significant RLS symptoms and to examine the life effects and medical experiences of this group. METHODS A total of 16 202 adults (aged >/=18 years) were interviewed using validated diagnostic questions to determine the presence, frequency, and severity of RLS symptoms; respondents reporting RLS symptoms were asked about medical diagnoses and the impact of the disorder and completed the Short Form-36 Health Survey (SF-36). Criteria determined by RLS experts for medically significant RLS (frequency at least twice a week, distress at least moderate) defined "RLS sufferers" as a group most likely to warrant medical treatment. RESULTS In all, 15 391 fully completed questionnaires were obtained; in the past year, RLS symptoms of any frequency were reported by 1114 (7.2%). Symptoms occurred at least weekly for 773 respondents (5.0%); they occurred at least 2 times per week and were reported as moderately or severely distressing by 416 (2.7%). Of those 416 (termed RLS sufferers), 337 (81.0%) reported discussing their symptoms with a primary care physician, and only 21 (6.2%) were given a diagnosis of RLS. The SF-36 scores for RLS sufferers were significantly below population norms, matching those of patients with other chronic medical conditions. CONCLUSION Clinically significant RLS is common (prevalence, 2.7%), is underdiagnosed, and significantly affects sleep and quality of life.
Design and evaluation of techniques for mobile interaction with dynamic NFC-displays

Near Field Communication (NFC) is a technology for mobile, touch-based interaction with tagged objects that can serve as physical user interfaces (UI). Dynamic NFC-displays use a grid of NFC-tags as a physical UI and combine it with a projected application UI to enable direct interactions between mobile devices and large screens. In this paper, we explore the design of interaction techniques for dynamic NFC-displays beyond the common touch-select interaction with single tags and evaluate them with an NFC-pinboard prototype. A user study confirms the general preference for the simple touch-select, but also shows that other techniques can provide alternatives, e.g. to implement interactions for which users want to feel more in control.
Rituximab for steroid-refractory chronic graft-versus-host disease.

B cells may be implicated in the pathophysiology of chronic graft-versus-host disease (GVHD), as evidenced by antibody production against sex-mismatched, Y chromosome-encoded minor HLA antigens in association with chronic GVHD. We therefore designed a phase 1/2 study of anti-B-cell therapy with rituximab in steroid-refractory chronic GVHD. Twenty-one patients were treated with 38 cycles of rituximab. Rituximab was tolerated well, and toxicity was limited to infectious events. The clinical response rate was 70%, including 2 patients with complete responses. Responses were limited to patients with cutaneous and musculoskeletal manifestations of chronic GVHD and were durable through 1 year after therapy. The median dose of prednisone among treated subjects fell from 40 mg/day to 10 mg/day, 1 year after rituximab therapy (P < .001). A chronic GVHD symptom score improved in the majority of treated patients. Antibody titers against Y chromosome-encoded minor HLA antigens fell and remained low, whereas titers against infectious antigens (EBV, tetanus) remained stable or rose during the treatment period. We conclude that specific anti-B-cell therapy with rituximab may be beneficial for patients with steroidrefractory chronic GVHD. This trial was registered at www.clinicaltrials. gov as #NCT00136396.
Integrated waveguide slot antenna and cavity filter using hollow SIW in LTCC technology

A hollow substrate integrated waveguide (HSIW) is proposed to realize low-loss millimetre-wave (mm-wave) transmission lines. A 38 GHz waveguide slot antenna integrated with a cavity bandpass filter is fabricated in LTCC to demonstrate the HSIW potential. The measured radiation pattern of the waveguide matches well with the simulations. The HSIW medium has great potential for further development and could be used to realize integrated passive elements such as filters, slot antennas and power combiners for future communications needs.
The Source of Spontaneous Activity in the Main Olfactory Bulb of the Rat

Introduction In vivo, most neurons in the main olfactory bulb exhibit robust spontaneous activity. This paper tests the hypothesis that spontaneous activity in olfactory receptor neurons drives much of the spontaneous activity in mitral and tufted cells via excitatory synapses. Methods Single units were recorded in vivo from the main olfactory bulb of a rat before, during, and after application of lidocaine to the olfactory nerve. The effect of lidocaine on the conduction of action potentials from the olfactory epithelium to the olfactory bulb was assessed by electrically stimulating the olfactory nerve rostral to the application site and monitoring the field potential evoked in the bulb. Results Lidocaine caused a significant decrease in the amplitude of the olfactory nerve evoked field potential that was recorded in the olfactory bulb. By contrast, the lidocaine block did not significantly alter the spontaneous activity of single units in the bulb, nor did it alter the field potential evoked by electrical stimulation of the lateral olfactory tract. Lidocaine block also did not change the temporal patters of action potential or their synchronization with respiration. Conclusions Spontaneous activity in neurons of the main olfactory bulb is not driven mainly by activity in olfactory receptor neurons despite the extensive convergence onto mitral and tufted cells. These results suggest that spontaneous activity of mitral and tufted is either an inherent property of these cells or is driven by centrifugal inputs to the bulb.
Licensed under Creative Commons Attribution Cc by Improving Network Management with Software Defined Networking

Network Management is very challenging. The Maintenance, operating and providing a secured communication network is very complex. It requires the network operators to grapple low-level vendor specific configurations to implement the high level network policies which are complex. The rigidity of underlying infrastructure presents few possibilities of improvement or innovation, since network devices are generally closed and vertically integrated. The solution to this problem is a new paradigm in networking; software defined networking (SDN), which advocates the separation of data plane and control plane. This separation makes the network switches in the data plane as simple packet forwarding devices and leaving a logically centralized software program to control the behavior of the entire network. We focus on three problems in network management. They are enabling frequent changes to network conditions and state, providing support for network configuration in high level language and providing better visibility and control over tasks for performing network trouble shooting.