Miracle-dz/UniFAR-FTUs huggingface dataset:
Power variation aware Configuration Adviser for scalable HPC schedulers

Efficient scheduling is crucial for time and cost-effective utilization of compute resources especially for high end systems. A variety of factors need to be considered during the scheduling decisions. Power variation across the compute resources of homogeneous large-scale systems has not been considered so far. This paper discusses the impact of the power variation for parallel application scheduling. It addresses the problem of finding the optimal resource configuration for a given application that will minimize the amount of consumed energy, under pre-defined constraints on application execution time and instantaneous average power consumption. This paper presents an efficient algorithm to do so, which also considers the existing power diversity among the compute nodes (modified also at different operating CPU frequencies) of a given homogeneous High Performance Computing system. Based on this algorithm, the paper presents a plug-in, referred to as Configuration Adviser, which operates on top of a given resource management and scheduling system to advise on energy-wise optimal resource configuration for a given application, execution using which, will adhere to the specified execution time and power consumption constraints. The main goal of this plug-in is to enhance the current resource management and scheduling tools for the support of power capping for future Exascale systems, where a data center might not be able to provide cooling or electrical power for system peak consumption but only for the expected power bands.
An investigation into the observed sex difference in prevalence of unipolar depression.

The rates of occurrence of unipolar depression as measured by self-report and by diagnosis based on semistructured interviews were examined in a longitudinal study with a general community sample (N = 998). Number of new cases, average age of onset, and average duration of episodes were comparable in men and women, but women with a history of previous depression were much more likely to become depressed again than men with a similar history. Data on a large number of demographic and psychological variables were collected on the subjects. Controlling for these factors (both singly and in combination) did not eliminate the sex difference in unipolar depression. Neither the artifact hypothesis (according to which the "true" prevalence of depression is equal for men and women) nor the psychosocial hypothesis (according to which women are more disadvantaged on relevant psychosocial variables) was supported by the data.
A monoclonal antibody (3G5)-defined ganglioside antigen is expressed on the cell surface of microvascular pericytes

The identification of microvascular pericytes in vitro relies principally on morphological characteristics and growth dynamics, as there is a paucity of immunochemical markers for these cells. Consequently, an attempt was made to identify mAb reagents that would aid in both the rapid identification and enrichment of retinal capillary pericytes in vascular cell cultures. A panel of mAbs raised by xenogeneic immunization of mice with various tissues was screened for immunoreactivity with dissociated cultures of bovine retinal capillary pericytes. Two antibodies from the panel (3G5 and HISL-8) were seen to react with pericytes by indirect immunofluorescence. The mAb 3G5 was selected for further study. mAb 3G5 did not react with dissociated cultures of smooth muscle cells, endothelial cells, or retinal pigmented endothelial cells. The pericyte 3G5 antigen was insensitive to the action of trypsin; therefore, mAb 3G5 was used to selectively purify pericytes from trypsinized mixed retinal cell cultures by flow cytometry. 3G5+ pericytes (representing 8% of cells in a mixed retinal cell culture) were enriched at least nine-fold to represent greater than 70% of cells. The mAb 3G5 stained retinal capillaries in vivo with a fluorescence distribution consistent with pericyte staining. The 3G5 antigen of cultured pericytes was found to be a glycolipid of mobility intermediate between ganglioside markers GM1 and GM2.
Mediterranean Journal of Hematology and Infectious Diseases Minimal Residual Disease in Acute Myeloid Leukemia of Adults: Determination, Prognostic Impact and Clinical Applications

Pretreatment assessment of cytogenetic/genetic signature of acute myeloid leukemia (AML) has been consistently shown to play a major prognostic role but also to fail at predicting outcome on individual basis, even in low-risk AML. Therefore, we are in need of further accurate methods to refine the patients' risk allocation process, distinguishing more adequately those who are likely to recur from those who are not. In this view, there is now evidence that the submicroscopic amounts of leukemic cells (called minimal residual disease, MRD), measured during the course of treatment, indicate the quality of response to therapy. Therefore, MRD might serve as an independent, additional biomarker to help to identify patients at higher risk of relapse. Detection of MRD requires the use of highly sensitive ancillary techniques, such as polymerase chain reaction (PCR) and multiparametric flow cytometry(MPFC). In the present manuscript, we will review the current approaches to investigate MRD and its clinical applications in AML management. Minimal residual disease in acute myeloid leukemia of adults: determination, prognostic impact and clinical applications. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by-nc/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Introduction. Acute myeloid leukemia (AML) is a clonal disorder of haemopoietic stem cells characterized by an abnormal proliferation of myeloid progenitors and subsequent bone marrow failure. AML response to chemotherapy is extremely variable with complete remission (CR) rates ranging from 50% to 80%. 1 Also frequency of relapse is variable, being reported in 10% to 95% of the cases. 2-4 Currently, risk-stratification is determined by several factors, patient-and disease-related, assessed at diagnosis, such as age,
Phosphate monoesterase and diesterase activities in the North and South Pacific Ocean

Phosphate monoesterase and diesterase activities were measured with soluble reactive phosphorus (SRP) and labile and total dissolved organic phosphorus (DOP) concentrations in the North and South Pacific Ocean, to reveal the microbial utilization of phosphate esters in the Pacific Ocean. Both esterase activities were noticeably enhanced around the western part of 30° N, where the surface SRP concentration was below 10 nM, while they showed no significant correlation with DOP concentration. The proportion of the activity in the dissolved fraction was higher for diesterase than monoesterase, which may support results from previous genomic analyses. Substrate affinity and the maximum hydrolysis rate of monoesterase were the highest at lower concentrations of SRP, showing the adaptation of microbes to inorganic phosphorus nutrient deficiency at the molecular level. The calculated turnover time of monoesters was 1 to 2 weeks in the western North Pacific Ocean, which was much shorter than the turnover time in other areas of the Pacific Ocean but longer than the turnover time in other phosphate-depleted areas. In contrast, the turnover rate of diesters was calculated to exceed 100 days, revealing that diesters in the western North Pacific were a biologically refractory phosphorus fraction. In the present study, it was revealed that both phosphate monoesters and diesters can be a phosphorus source for microbes in the phosphate-depleted waters, although the dynamics of the two esters are totally different.
Apuntes críticos sobre teorías y tipologías del liderazgo organizacional

El presente articulo tiene como finalidad realizar una valoracion critica de las principales teorias de liderazgo organizacional desarrolladas por diversos autores. El analisis parte de la evolucion historica de estas teorias y los fundamentos que sustentan cada una de ellas. Igualmente se abordan las diferentes tipologias del liderazgo. Entre las principales teorias consideradas se destacan las que conciben el liderazgo como personalidad, como conducta, el transformacional y el humanista. La valoracion planteada en este articulo se fundamenta en la consideracion del papel protagonico que le corresponde asumir a los lideres y sus seguidores para el lograr el desempeno exitoso de las organizaciones. El trabajo evidencia la necesidad de desarrollar en las organizaciones un liderazgo transformador y humanista, sustentado en principios eticos, valores y competencias de exito.
Haptic feedback in motor hand virtual therapy increases precision and generates less mental workload

In this work we show that haptic feedback in upper limb motor therapy improves performance and generates a lower mental workload. To demonstrate this, two groups of participants (healthy adults and elders with hand motor problems) used a low-cost haptic device (Novint Falcon) and a non-robotic device (Leap Motion Controller). Participants conducted the same rehabilitation task by using a non-immersive virtual environment. Results show significant differences for all participants regarding precision on the use of the haptic feedback device. Additionally, participants in the older adult group demonstrated a lower mental workload while using the haptic device (Novint Falcon). Finally, qualitative results show that participants preferred to conduct their therapy exercises by using the haptic device, as they found it more useful, easier to use and easier to learn.
Characteristics of buffer overflow attacks tunneled in HTTP traffic

The purpose of this article is to describe characteristics of obfuscated network buffer overflow attacks in contrast with characteristics of directly simulated attacks. The obfuscation was performed by tunneling of malicious traffic in HTTP and HTTPS protocols. These protocols wrap a malicious communication between an attacker situated outside of an intranet and a callback located inside of an intranet. The detection analysis which we perform is based on features extraction from network packets dumps and it employs a behavioral and statistical analysis of communications' progress in time and packet index domain. There were performed experiments in four scenarios simulating traffic shaping, traffic policing and transmission on unreliable network channel to make properties of direct attacks and obfuscated attacks as various as possible. Next part of this article is comparison of obfuscated and direct attacks classification by our previously designed ASNM network features with state-of-the-art features set of A. Moore, both representing statistical and behavioral based experimental academic kernels for NBA. Presented results show better classification accuracy of ASNM features in all kinds of experiments.
QUANTUM WITTEN LOCALIZATION AND ABELIANIZATION

We prove a quantum version of the localization formula of Witten [74], see also [70], [61], [78], that relates invariants of a git quotient with the equivariant invariants of the action. Using the formula we prove a quantum version of an abelianization formula of S. Martin [48], relating invariants of geometric invariant theory quotients by a group and its maximal torus, conjectured by Bertram, Ciocan-Fontanine, and Kim [13]. By similar techniques we prove a quantum Lefschetz principle for holomorphic symplectic reductions. As an application, we give a formula for the fundamental solution to the quantum differential equation (qde) for the moduli space of points on the projective line and for the smoothed moduli space of framed sheaves on the projective plane (a Nakajima quiver variety).
Mapping the extent of abandoned farmland in Central and Eastern Europe using MODIS time series satellite data

The demand for agricultural products continues to grow rapidly, but further agricultural expansion entails substantial environmental costs, making recultivating currently unused farmland an interesting alternative. The collapse of the Soviet Union in 1991 led to widespread abandonment of agricultural lands, but the extent and spatial patterns of abandonment are unclear. We quantified the extent of abandoned farmland, both croplands and pastures, across the region using MODIS NDVI satellite image time series from 2004 to 2006 and support vector machine classifications. Abandoned farmland was widespread, totaling 52.5 Mha, particularly in temperate European Russia (32 Mha), northern and western Ukraine, and Belarus. Differences in abandonment rates among countries were striking, suggesting that institutional and socio-economic factors were more important in determining the amount of abandonment than biophysical conditions. Indeed, much abandoned farmland occurred in areas without major constraints for agriculture. Our map provides a basis for assessing the potential of Central and Eastern Europe’s abandoned agricultural lands to contribute to food or bioenergy production, or carbon storage, as well as the environmental trade-offs and social constraints of recultivation.
On the design of single-inductor multiple-output DC-DC buck converters

Design techniques for single inductor multiple output (SIMO) DC-DC buck converters are presented. The suitable control of a multiple feedback loop enables the sharing of a single inductor with many outputs with a good stability and limited cross regulation. The method has been verified with simulations at the behavioural and transistor level to obtain four independent regulated output voltages ranging from 0 V to 1 V below the power supply voltage. The use of a suitable analog processing of errors allows obtaining a power efficiency as high as 86%.
A combinatorial analysis and a closed-form analytical expression for the signal to third-order distortion ratio in OFDM signals through smooth memoryless nonlinearity

In this paper we present a combinatorial analysis that explicitly exposes the exact number, weight and relative phase contributions of individual in-band signal subcarriers, for the in-band nonlinear distortion, experienced by a specific subcarrier in a nonlinearly distorted multicarrier Orthogonal Frequency Division Multiplex (OFDM) signal. This analysis is based on a discrete model of the passband signal and a polynomial smooth memoryless model of the nonlinearity. A closed-form analytical formula for the in-band intermodulation distortion is derived, which precisely quantifies the Signal to Third-Order Distortion Ratio for each subcarrier, permitting the calculation of the individual subcarrier and the overall OFDM signal Bit Error Rate (BER) performance. The motivation is the development of a simple and accurate analytical tool for the characterization of the nonlinear distortion performance of systems that use amplification for antenna received DVB-T signals. Our approach follows a straightforward combinatorial analysis and requires minimum signal and nonlinearity information.
Implementation and simulation of single phase active shunt power filter

Active power filtering is one of the most promising and mature technologies used for eradication of harmonics in power systems. This paper presents the implementation and simulation of shunt active power filter with diode rectifier connected to RL Load. Generation of reference fundamental load current signal is done without calculating load active power. The simulation results are analyzed and THD-I of source current is compared in both cases (with and without filter) to bring out the effects of active power filter on source current. The results show successful reduction of harmonics from source current.
Dynamic Annotation of Interactive Environments using Object-Integrated Billboards

We present a technique for the dynamic annotation of three-dimensional objects in interactive virtual environments. Annotations represent textual or symbolic descriptions providing explanatory or thematic information associated with scene objects. In contrast to techniques that treat annotations as two-dimensional view-plane elements, our technique models annotations as separate three-dimensional scene elements that are automatically positioned and oriented according to the shape of the referenced object. The shape of such an object is generalized by an annotation hull and skeleton used to determine an adequate position and orientation of the annotation with respect to the viewing direction. During camera movements, annotations float along the surface of the annotation hull. Additional constraints for the generalizations provide further control about geometric and dynamical properties. In a case study, we show how this technique can be applied for annotating buildings and other components of virtual 3D city models.
Novel alpha-D-mannosidase of rat sperm plasma membranes: characterization and potential role in sperm-egg interactions

During the course of a study of glycoprotein processing mannosidases in the rat epididymis, we have made an intriguing discovery regarding the presence of a novel alpha-D-mannosidase on the rat sperm plasma membranes. Unlike the sperm acrosomal "acid" mannosidase which has a pH optimum of 4.4, the newly discovered alpha-D-mannosidase has a pH optimum of 6.2, and 6.5 when assayed in sperm plasma membranes and intact spermatozoa, respectively. In addition, the two enzymes show different substrate specificity. The acrosomal alpha-D-mannosidase is active mainly towards synthetic substrate, p-nitrophenyl alpha-D- mannopyranoside, whereas the sperm plasma membrane alpha-D-mannosidase shows activity mainly towards mannose-containing oligosaccharides. Evidence is presented which suggest that the sperm plasma membrane alpha-D-mannosidase is different from several processing mannosidases previously characterized from the rat liver. The newly discovered alpha- D-mannosidase appears to be an intrinsic plasma membrane component, since washing of the purified membranes with buffered 0.4 M NaCl did not release the enzyme in soluble form. The enzyme requires nonionic detergent (Triton X-100) for complete solubilization. The enzyme is activated by Co2+ and Mn2+. However, Cu2+ and Zn2+ are potent inhibitors of the sperm plasma membrane alpha-D-mannosidase. At a concentration of 0.1 mM, these divalent cations caused nearly complete inactivation of the sperm enzyme. In addition methyl-alpha-D-mannoside, methyl-alpha-D-glucoside, mannose, 2-deoxy-D-glucose, and D-mannosamine are inhibitors of the sperm surface alpha-D-mannosidase. The physiological role of the newly discovered enzyme is not yet known. Several published reports in three species, including the rat, suggest that the sperm surface alpha-D-mannosidase may have a role in binding to mannose-containing saccharides presumably present on the zona pellucida.
Concepts of Dignity: Human Dignity and Personal Dignity

INTRODUCTION This thesis reports on research into the ways patients with severe chronic or life-threatening illnesses understand and experience their sense of personal dignity. In this introductory chapter, the aims of the research project are described and a short overview of the methods is provided. Before doing so, usage of the concept of dignity within the context of medicine and healthcare is briefly examined from a theoretical perspective. The concept of dignity (dignitas (Latin), "worthiness") boasts a long philosophical tradition dating back, at least, to Roman and Greek Antiquity, and its meaning has changed along sociocultural and historical lines (Gallagher et al. In the 20th century, physicians and medical and healthcare researchers began showing an interest in the concept of dignity. The concept they were concerned with was 'human dignity', a notion of dignity that had first gained wide recognition through the Enlightenment philosophy of Immanuel Kant (1724-1804). Kant stated that all human beings possess dignity (Würde) by virtue of their rationality. Although the grounds for human dignity have been debated (Malvestiti, 2012), the belief that all humans possess dignity and that this dignity is inalienable has influenced modern thinking since the Second World War. Human dignity proclaims that all human beings possess inherent worth irrespective of rank, station, or any other contingent quality. They therefore deserve to be treated with respect and are entitled to basic rights, such as the right to self-determination and the right not to be harmed. Thus, human dignity denotes the equal worth of all humans; every human has dignity, therefore any discrimination between persons would be unjustified and immoral on the grounds of dignity. Human dignity is an overarching, fundamental principle that refers, on the one hand, to an ethical principle regarding the notions of what it means to be human and how to treat people humanely, stating that the obligation to respect human dignity is a moral absolute, and, on the other hand, to a juridical principle that lies at the heart of legislation concerning the basic human rights enshrined in national and international laws and policies, e.g. in the United Nation's Universal Declaration of Human Rights (1948). The concern with human dignity in medicine was triggered by the discovery of the atrocities committed by Nazi physicians working in concentration camps (Burns, 2008).
Integrating Off-line and On-line Scheduling Approaches

Solving a scheduling problem consists in finding an initial solution able to model all the complex constraints that relate the problem activities. Moreover, the solving process should be necessarily considered as propaedeutic for the next phase of any schedule’s life: its execution in the real world. The inherent unpredictability of real working environments poses serious difficulties to which the scheduling community normally responds by (1) introducing methodologies that tend to increase schedule robustness (off-line phase, proactive approach), and by (2) developing fast-reaction techniques to be employed during schedule execution (on-line phase, reactive approach). In the previous edition of this workshop we presented a benchmark generator for the reactive scheduling problem. This problem consists in monitoring the execution of a schedule and repairing it every time it is deemed necessary. The main motivation behind our previous work came out from the recognized lack (hence the necessity) of benchmark sets for this specific problem. In this paper we provide an empirical study based on the same benchmark generator which focuses on the mutual interactions among a set of off-line and on-line constraint-based scheduling approaches. We devise a set of closed loop execution management algorithms, and compare their behavior within an experimental framework which allows to directly assess the consequences of each chosen strategy combination, through simulated schedule executions. A number of interesting results are described that open new perspectives for future work based on this integrated schema.