Miracle-dz/UniFAR-FTUs huggingface dataset:
Maternal HealthCare Using IoT-Based Integrated Medical Device: Bangladesh Perspective

Purpose: The main purpose of this study is to develop a low-cost integrated medical device. This device will help investigate the risk levels of maternal patients as well will reduce the cost involved in medical diagnosis for poor countries like Bangladesh, where maternal healthcare is a great concern. Methodology: We proposed and developed an integrated medical device that includes all possible sensors to collect raw data from maternal patients. As soon as the data is collected it will be sent to the cloud for processing. In the cloud, there are a set of algorithms (software) for processing raw data received from the device. After processing and analyzing our system will automatically identify the risk levels of those patients. The software is developed in open source code so that in the future it can be updated by researchers. Results: We developed the system and practically collected raw data from patients and uploaded those data to our cloud system. In the cloud, it was processed and the resultant data were presented in the form of graphs. From these graphs, the risk levels were identified. Limitations: The proposed system is developed for maternal patients only. This system needs to be authorized by the health regulatory authority. To make it cost-effective some expensive sensors were not used. Contribution: The main contribution of this study is to minimize the cost involved in maternal healthcare in poor countries like Bangladesh. This, in turn, controls the death of mother and child by improving maternal healthcare facilities.
Human daily activity recognition by fusing accelerometer and multi-lead ECG data

Human daily activity recognition has gained much attention since it has a wide range of applications. In this paper, we propose a novel scheme for recognizing human daily activity by fusing multiple wearable sensors, i.e., accelerometer and multi-lead ECG. Firstly, both time and frequency domain features are extracted from raw sensor data. In order to alleviate the computation complexity of subsequent process, the dimensions of feature vectors would be sharply reduced by performing linear discriminant analysis (LDA). Then, the reduced feature vectors are classified by relevance vector machines (RVM). Finally, considering different sensors and leads would provide complementary information about the human activity, the individual classification results are fused at the decision level to improve the overall recognition performance. Experimental results show that if seven leads of ECG and accelerometer are fused, we can even achieve recognition accuracy as high as 99.57%. Furthermore, the proposed scheme has great potential in real-time applications due to its strong ability in feature dimensionality reduction, simple classifier structure, and perfect recognition performance.
Plasmin-Sensitive Dibasic Sequences in the Third Fibronectin-like Domain of L1–Cell Adhesion Molecule (CAM) Facilitate Homomultimerization and Concomitant Integrin Recruitment

L1 is a multidomain transmembrane neural recognition molecule essential for neurohistogenesis. While moieties in the immunoglobulin-like domains of L1 have been implicated in both heterophilic and homophilic binding, the function of the fibronectin (FN)-like repeats remains largely unresolved. Here, we demonstrate that the third FN-like repeat of L1 (FN3) spontaneously homomultimerizes to form trimeric and higher order complexes. Remarkably, these complexes support direct RGD-independent interactions with several integrins, including αvβ3 and α5β1. A pep- tide derived from the putative C-C′ loop of FN3 (GSQRKHSKRHIHKDHV852) also forms trimeric complexes and supports αvβ3 and α5β1 binding. Substitution of the dibasic RK841 and KR845 sequences within this peptide or the FN3 domain limited multimerization and abrogated integrin binding. Evidence is presented that the multimerization of, and integrin binding to, the FN3 domain is regulated both by conformational constraints imposed by other domains and by plasmin- mediated cleavage within the sequence RK↓HSK↓RH846. The integrin α9β1, which also recognizes the FN3 domain, colocalizes with L1 in a manner restricted to sites of cell–cell contact. We propose that distal receptor ligation events at the cell–cell interface may induce a conformational change within the L1 ectodomain that culminates in receptor multimerization and integrin recruitment via interaction with the FN3 domain.
Exploiting Context to Identify Lexical Atoms - A Statistical View of Linguistic Context

Interpretation of natural language is inherently context-sensitive. Most words in natural language are ambiguous and their meanings are heavily dependent on the linguistic context in which they are used. The study of lexical semantics can not be separated from the notion of context. This paper takes a contextual approach to lexical semantics and studies the linguistic context of lexical atoms, or "sticky" phrases such as "hot dog". Since such lexical atoms may occur frequently in unrestricted natural language text, recognizing them is crucial for understanding naturally-occurring text. The paper proposes several heuristic approaches to exploiting the linguistic context to identify lexical atoms from arbitrary natural language text.
Coffee consumption, alcohol use, and cigarette smoking as determinants of serum total and HDL cholesterol in two Serbian cohorts of the Seven Countries Study.

The associations between serum total and HDL cholesterol and three lifestyle factors--consumption of Turkish coffee, consumption of alcohol, and cigarette smoking--were examined in two Serbian cohorts of the Seven Countries Study. In 1988 and 1989, 319 men from Zrenjanin and Belgrade, 65 to 84 years old and free of myocardial infraction, participated. The men from Zrenjanin were originally working in a large cooperative, and the men from Belgrade were faculty members of the university. HDL cholesterol, alcohol consumption, and cigarette smoking were significantly higher in Zrenjanin than in Belgrade. Serum total cholesterol levels and coffee consumption were not different. ANCOVA showed that serum total cholesterol levels were 8.2% higher (P < .05) in men consuming two small cups of coffee per day compared with abstainers, and this was also seen after adjustment for cigarette smoking, age, body mass index, cohort, and alcohol consumption. In men consuming one or more alcoholic drinks per day (more than 10 g/d alcohol), HDL cholesterol levels were increased by 0.19 mmol/L (15.4%) compared with men consuming no alcohol (P < .001). This association was stronger in the Zrenjanin cohort than in the Belgrade cohort (P < .05). Smoking was not associated with total cholesterol or with HDL cholesterol levels. In Serbian men, boiled Turkish coffee and alcohol consumption are independently associated with serum total and HDL cholesterol levels, respectively.
SiSMA-a tool for efficient analysis of analog CMOS integrated circuits affected by device mismatch

In this paper a simulator for the statistical analysis of analog CMOS integrated circuits affected by technological tolerance effects, including device mismatch, is presented. The tool, able to perform dc, ac, and transient analyses, is based on a rigorous formulation of circuit equations starting from the modified nodal analysis and including random current sources to take into account technological tolerances. Statistical simulation of specific circuits shows that the simulator requires a simulation time several orders of magnitude lower than that required by Monte Carlo analysis, while ensuring a good accuracy.
The Effects of Urbanization and Human Disturbance Upon Plant Community Structure and Bird Species Richness, Diversity, and Abundance in a Natural Forested Area (Forest Park) in Portland, Oregon

This Dissertation is brought to you for free and open access. It has been accepted for inclusion in Dissertations and Theses by an authorized administrator of PDXScholar. For more information, please contact pdxscholar@pdx.edu. Recommended Citation Broshot, Nancy Ellen, "The Effects of Urbanization and Human Disturbance Upon Plant Community Structure and Bird Species Richness, Diversity, and Abundance in a Natural Forested Area (Forest Park) in Portland, Oregon" (1999). Dissertations and Theses. Paper 3962.
Inhibition of T Helper Cell Type 2 Cell Differentiation and Immunoglobulin E Response by Ligand-Activated Vα14 Natural Killer T Cells

Murine Vα14 natural killer T (NKT) cells are thought to play a crucial role in various immune responses, including infectious, allergic, and autoimmune diseases. Because Vα14 NKT cells produce large amounts of both interleukin (IL)-4 and interferon (IFN)-γ upon in vivo stimulation with a specific ligand, α-galactosylceramide (α-GalCer), or after treatment with anti-CD3 antibody, a regulatory role on helper T (Th) cell differentiation has been proposed for these cells. However, the identity of the cytokine produced by Vα14 NKT cells that play a dominant role on the Th cell differentiation still remains controversial. Here, we demonstrate by using Vα14 NKT-deficient mice that Vα14 NKT cells are dispensable for the induction of antigen-specific immunoglobulin (Ig)E responses induced by ovalbumin immunization or Nippostrongylus brasiliensis infection. However, upon in vivo activation with α-GalCer, Vα14 NKT cells are found to suppress antigen-specific IgE production. The suppression appeared to be IgE specific, and was not detected in either Vα14 NKT– or IFN-γ–deficient mice. Consistent with these results, we also found that ligand-activated Vα14 NKT cells inhibited Th2 cell differentiation in an in vitro induction culture system. Thus, it is likely that activated Vα14 NKT cells exert a potent inhibitory effect on Th2 cell differentiation and subsequent IgE production by producing a large amount of IFN-γ. In marked contrast, our studies have revealed that IL-4 produced by Vα14 NKT cells has only a minor effect on Th2 cell differentiation.
POTENTIAL CONSEQUENCES OF THE BRCA 1 MUTATION CARRIER STATE ON ESTROGEN RESPONSIVE ORGANS

Incessant menstrual cycle activity, uninterrupted by either pregnancy or oral contraceptive use, is the most important risk factor for sporadic ovarian cancer. Menstrual cycle progression is partly controlled by steroid hormones such as estrogens and others that are secreted by ovarian granulosa cells. We showed earlier that mice carrying a homozygous granulosa cell specific knock out of Brca1, the homolog of BRCA1that is associated with familial ovarian cancer predisposition in humans, develop benign epithelial tumors in their reproductive tract. These tumors are driven, at least in part, by a prolongation of the proestrus phase of the estrus cycle (equivalent to the follicular phase of the menstrual cycle) in Brca1 mutant mice, resulting in prolonged unopposed estrogen stimulation. Mutant mice synchronized in proestrus also showed increased circulating estradiol levels, but the possibility that this changealso plays a role in tumor predisposition was not investigated. We sought to determine whether these changes in hormonal stimulation result in measurable changes in tissues targeted by estrogen outside the ovary. Here we show that mice carrying a Brca1 mutation in ovarian granulosa cells show increased endometrial proliferation during proestrus, implying that the effects of Brca1 inactivation on estrogen stimulation have short-term consequences, at least on this target organ. We further show that mutant mice develop increased femoral trabecular thickness and femoral length, which are well-known consequences of chronic estrogen stimulation. Estrogen biosynthesis by granulosa cells was increased not only in Users may view, print, copy, download and text and datamine the content in such documents, for the purposes of academic research, subject always to the full Conditions of use: http://www.nature. com/authors/editorial_policies/license.html#terms Corresponding author: Louis Dubeau, Ezralow Tower room 6338, USCNorris, Comprehensive Cancer Center, 1441 Eastlake Avenue, Los Angeles, CA 90033; ldubeau@usc.edu; tel: 323-865-0720; fax: 323-865-0077. Conflict of interest: none declared. HHS Public Access Author manuscript Lab Invest. Author manuscript; available in PMC 2015 August 10. Published in final edited form as: Lab Invest. 2012 June ; 92(6): 802–811. doi:10.1038/labinvest.2012. 58. A uhor M anscript
Using multiple sensors for mobile sign language recognition

We build upon a constrained, lab-based Sign Languagerecognition system with the goal of making it a mobile assistivetechnology. We examine using multiple sensors for disambiguationof noisy data to improve recognition accuracy.Our experiment compares the results of training a smallgesture vocabulary using noisy vision data, accelerometerdata and both data sets combined.
Deterioration of Groundwater in Beirut Due to Seawater Intrusion

All of Lebanon’s aquifers, without exception, are afflicted with some form of contamination, be it from untreated raw sewage, pesticides or fertilizers, but at the forefront there is seawater intrusion, and nowhere it is more pronounced than in Beirut, the capital. Extensive sampling of Beirut’s groundwater in recent years has revealed alarming values of Total Dissolved Solids (TDS) in the thousands of milligrams per litre, in an increasing number of wells. This irreversible deterioration of groundwater quality is forcing citizens to install costly desalination equipment, importing questionable water by private tankers or abandoning their wells altogether. Initial groundwater sampling began in 2004. In what was possibly Lebanon’s worst drought in decades, another campaign to sample Beirut’s groundwater was undertaken in the summer of 2014 which still continues to date. Acute water shortages in recent years coupled with recurrent periods of drought, have rendered Total Dissolved Solids (TDS) of many sampled wells in Beirut, equivalent to that of seawater (~37,500 mg/L). Fundamental in combating the impact of seawater intrusion however is an understanding of the Ghyben-Herzberg principle which warns that for every meter of groundwater drop above sea level there is an equivalent rise of 40 meters of the saline-fresh water interface, demonstrating just how sensitive over-pumping is in coastal aquifers. With an understanding of the principle dynamics behind the phenomena of seawater intrusion, myriad methods may then be employed to combat this encroachment in coastal aquifers. Restricting or even preventing altogether withdrawals from Beirut’s coastal aquifers may however be the only viable option left.
[Effect of Chinese herbal drug-containing serum for activating blood, activating blood and dispelling toxin on TNF-alpha-induced adherence between endothelial cells and neutrophils and the expression of MAPK pathway].

OBJECTIVE To explore the effect of drug-containing serum of Chinese herbal compounds [Xiongshao Capsule (XS, for activating blood) and Huanglian Capsule (HL, for dispelling toxin)] on tumor necrosis factor-alpha (TNF-alpha)-induced adherence between human umbilical vein endothelial cells (HUVECs) and polymorphonuclear neutrophils (PMN), inflammatory reaction and expression of related proteins in mitogen-activated protein kinase (MAPK) pathway. METHODS Thirty-two rats were randomly divided into four groups (8 in each group) using random digit table: the blank control group treated with distilled water, the test group I treated with Chinese herbal compound of XS (0.135 g/kg), the test group II treated with Chinese herbal compound of HL (0.135 g/kg), and the test group Ill treated with Chinese herbal compound of XS (0.135 g/kg) and HL (0.135 g/kg). All medication was given by gastrogavage once a day for a week. Rats' blood serum was harvested 1 h after the last administration to prepare drug-containing serum. HUVECs were exposed to TNF-alpha (100 ng/mL) to induce cell injury model and incubated with corresponding drug-containing serum (10%) for 24 h. Normal rats' serum was given to cells in the blank control group and the model group, while XC + HL containing serum was given to cells in the rest 3 groups. The adherence of HUVECs and PMN cells was detected by using rose bengal strain. Levels of E-selectin, intercellular adhesion molecule-1 (ICAM-1), and interleukin-1beta (IL-1P) in the supernatant of cultured HU-VECs were determined by ELISA. Protein expressions of mitogen-activated protein kinases p38 (p38MAPK) and extracellular signal-regulated kinase 1/2 (ERK 12) were determined by Western blot. RESULTS Compared with the blank control group, HUVECs were seriously injured; PMN adherence amount significantly increased; levels of E-selectin, ICAM-1, and IL-1beta increased; expression levels of p-p38MAPK and p-ERK 1/2 in the supernatant of HUVECs significantly increased in the model group (all P < 0.01). Compared with the model group, HUVECs-PMN adherence amount decreased (P < 0.05); levels of E-selectin, ICAM-1, and IL-1 beta in the supernatant of HUVECs decreased (P < 0.01, P < 0.05); expression levels of p-p38MAPK and p-ERK 1/2 of endothelial cells decreased in the test group I, II, and III (P < 0.01). CONCLUSIONS Drug-containing serums of activating blood, activating blood and dispelling toxin could attenuate TNF-alpha induced injury of HUVECs, inhibit HUVECs-PMN adherence and the release of adhesion factors. Its mechanism might be involved with protein phosphorylation of p38MAPK and ERK 1/2 in the MAPK pathway.
Good Governance and Public Trust

The success of a democratic country is the increasing public trust in the government. With increasing public trust, it is hoped that the community can participate in the government development process. One way that can be done to increase trust is good governance. Good governance itself consists of responsiveness, accountability, and transparency. However, in Indonesia, people's trust in the government has declined, contributing to the ineffectiveness of the government's performance. The number of corruption cases in Indonesia has also caused a decline in public trust. Therefore, this study aims to determine whether responsiveness, accountability, and transparency affect public trust. The novelty of this research is the use of data processing methods. The research method used was distributing questionnaires and then processing the data using SEM PLS. The research results show that responsiveness, accountability, and transparency affect public trust. The results of this study are anticipated to help government institutions promote good governance and boost community trust. Furthermore, this research is expected to enhance the community's understanding of the importance of information and communication technology in evaluating government performance.
Towards a unified framework for hand-based methods in First Person Vision

First Person Vision (Egocentric) video analysis stands nowadays as one of the emerging fields in computer vision. The availability of wearable devices recording exactly what the user is looking at is ineluctable and the opportunities and challenges carried by this kind of devices are broad. Particularly, for the first time a device is so intimate with the user to be able to record the movements of his hands, making hand-based applications for First Person Vision one the most explored area in the field. This paper explores the more popular processing steps to develop hand-based applications, and proposes a hierarchical structure that optimally switches between each of the levels to reduce the computational cost of the system and improve its performance.
Towards a multi-scale approach for source code approximate match report

Finding exact clones in source code can be efficiently handled using classical exact substring or subtree pattern matching techniques inspired from genomics applications. These methods may be wisely employed as a foundation to sketch new techniques highlighting duplicated code chunks presenting minor edits or more extensive modifications at a higher structural scale. The main goal is to improve recall of small near matches and to aggregate them into larger ones to provide a more global view of similarities with a reasonable complexity. These concerns are essential to be able to address a large database of source code projects.
P-GLYCOPROTEIN PLAYS A MAJOR ROLE IN THE EFFLUX OF FEXOFENADINE IN THE SMALL INTESTINE AND BLOOD-BRAIN BARRIER, BUT ONLY A LIMITED ROLE IN ITS BILIARY EXCRETION

Fexofenadine is a selective, nonsedating H1-receptor antagonist approved for symptoms of allergic conditions, which is mainly excreted into feces via biliary excretion. The purpose of this study is to investigate its pharmacokinetics in mice and rats to determine the role of P-glycoprotein (P-gp) in its biliary excretion. In mice, biliary excretion clearance (17 ml/min/kg) accounted for almost 60% of the total body clearance (30 ml/min/kg). Comparing the pharmacokinetics after intravenous and oral administration indicated that the bioavailability of fexofenadine was at most 2% in mice. Knockout of Mdr1a/1b P-gp did not affect the biliary excretion clearance with regard to both plasma and liver concentrations, whereas the absence of P-gp caused a 6-fold increase in the plasma concentration after oral administration. In addition, the steady-state brain-to-plasma concentration ratio of fexofenadine was approximately 3-fold higher in Mdr1a/1b P-gp knockout mice than in wild-type mice. Together, these results show that P-glycoprotein plays an important role in efflux transport in the brain and small intestine but only a limited role in biliary excretion in mice. In addition, there was no difference in the biliary excretion between normal and hereditarily multidrug resistance-associated protein 2 (Mrp2)-deficient mutant rats (Eisai hyperbilirubinemic rats) and between wild-type and breast cancer resistance protein (Bcrp) knockout mice. These results suggest that the biliary excretion of fexofenadine is mediated by unknown transporters distinct from P-gp, Mrp2, and Bcrp.
A small file performance optimization algorithm on P2P distributed file system

With the further development of the Internet, the amount of data on the network grows exponentially in recent years. While the fastest increasing objects are the mass small files from blogs, forums, etc. Master/Slave structure distributed file systems have some shortcomings, such as the poor access performance with small files, single-point bottlenecks, etc. Although these problems have been solved in the P2P structure distributed file system to some extent, there is still some improvement room of accessing performance for small files in the P2P structure distributed file system, so a small file merging strategy(SFMS) is proposed in this paper. The throughput rate of reading small files is increased significantly. Experiments show that the throughput rate of reading small files is increased by 90% compared with the original system, and 25 times higher than the TFS which is based on Master/Slave structure.
Time-Series Estimation of Structural Import Demand Equations: A Cross-Country Analysis

A structural import demand equation is derived and estimated for a large number of countries, using recent time-series techniques that address the problem of nonstationarity. The average price elasticity is close to zero in the short run but is slightly higher than one in the long run. A similar pattern holds for income elasticities: the short-run income elasticities are on average less than 0.5, while the long-run income elasticities are close to 1.5. The paper also analyses the small-sample properties of both the ordinary-least-squares (OLS) and the fully modified (FM) estimators of the short- and long-run elasticities, using Monte Carlo methods.