Miracle-dz/UniFAR-FTUs huggingface dataset:
Prevalence of Non-Alcoholic Fatty Liver Disease and Its Predictors in North of Iran

Abstract Background Nonalcoholic fatty liver disease (NAFLD) is one of the aspects of metabolic syndrome (MetS). Due to the increase of MetS in Iran, this study was conducted to determine the prevalence of NAFLD, its potential predictors and their sex distribution in north of Iran, Amol. Methods In 2008 this population based cross-sectional study included 5023 adult individuals who were randomly selected from Amol healthcare centers. Blood analysis and hepatic sonography was performed for each individual and Clinical histories were reviewed. MetS was defined according to the National Cholesterol Education Program Adult Treatment Panel III. Chi-square test, univariate and multivariate logistic regression were used to analyze data. Results The prevalence of NAFLD and metabolic syndrome was 43.8% and 29.6% respectively. Both NAFLD and metabolic syndrome were significantly more prevalent in women. There was a stronger association between these two factors in women which may indicate MetS has a much more potency to result in NAFLD in women. The strongest predictors of NAFLD in men were waist circumference>102 cm, serum ALT ≥40 (U/L) and the age group of 40-60 years. The strongest predictors of NAFLD in women were waist circumference>88 cm, the age groups of 40-60 and >60 years. Conclusions The observed prevalence is alarming because almost 7out of 10 subjects with MetS had NAFLD. As high waist circumference was an important predictor of NAFLD in both sexes, health care policies to reduce the incidence of obesity in the country will have an important impact on the occurrence of NAFLD.
A high-efficiency PA with peak PAE of 32.9% and 12.7 dBm P1dB for 60 GHz beamforming applications in SiGe

A fully integrated differential power amplifier, produced in 130 nm SiGe process for 60 GHz application is presented. The PA features one-stage cascade topology with measured gain of 17.5 dB. The measured differential 1dB compression point (P1dB) at the output is 12.7 dBm, and the measured saturated power is 13.3 dBm. Power consumption at P1dB is 57.1 mW. The measured peak power-aided efficiency is 32.9%. To the best knowledge of authors, this is a record value for 60 GHz PAs in SiGe and CMOS.
Designing virtual topologies in flexible optical networks

A set of techniques to design the virtual topology for flexible optical networks is presented. They are based on previous algorithms proposed for fixed-grid optical networks, which are adapted and optimized to the characteristics of flexible networks. A simulation study is presented to evaluate their performance. The technique that obtains the best result is based on genetic algorithms and enhanced with a cognitive technique.
BINDING OF COLCHICINE-3H TO VINBLASTINE- AND VINCRISTINE-INDUCED CRYSTALS IN MAMMALIAN TISSUE CULTURE CELLS

the vinca alkaloids, vinblastine sulfate and vincristine sulfate (Velban and Oncovin, respectively ; Eli Lilly and Co ., Indianapolis, Ind .), cause hypertrophy of the granular endoplasmic reticulum and annulate lamellae in cultured mammalian cells (7), and the accumulation of large proteinaceous cytoplasmic crystals in tissue culture cells (8), in cells of the central nervous system (9), and in platelets (10) . In electron micrographs, longitudinally cut crystals show a substructure of parallel, electron-opaque lines with approximately 280 A periodicity while in cross-sections a honeycomblike arrangement of tubules, 280 A wide, is seen . Association of large arrays of ribosomes and polyribosomes with the crystals has been recently demonstrated (11, 12) . In cells reincubated in fresh medium after the formation of the vinblastineinduced crystals, large masses of 50-80 A filaments are seen instead of the crystals, suggesting that the crystals and the filaments are interconvertible (11) . Precipitation of a colchicine-binding protein (isolated and characterized earlier [13]) from the high-speed supernates of homogenized tissue culture cells and pig brain, and from isolated microtubular protein, by vinblastine has been reported (14, 15) . Precipitation of structural proteins other than the colchicine-binding microtubular proteins by vinblastine has been recently demonstrated (16) . In view of these observations, it is important to consider whether or not the proteins forming the intracellular cytoplasmic crystals are similar to the colchicine-binding microtubular proteins (13) and the proteins precipitated by vinblastine and vincristine from the supernates of the cell homogenates (14, 15) . BRIEF NOTES
Human Infection with a Novel Avian-Origin Influenza A (H7N9) Virus.

HAL is a multi-disciplinary open access archive for the deposit and dissemination of scientific research documents, whether they are published or not. The documents may come from teaching and research institutions in France or abroad, or from public or private research centers. L’archive ouverte pluridisciplinaire HAL, est destinée au dépôt et à la diffusion de documents scientifiques de niveau recherche, publiés ou non, émanant des établissements d’enseignement et de recherche français ou étrangers, des laboratoires publics ou privés. Human Infection with a Novel Avian-Origin Influenza A (H7N9) Virus. Rongbao Gao, Bin Cao, Yunwen Hu, Zijian Feng, Dayan Wang, Wanfu Hu, Jian Chen, Zhijun Jie, Haibo Qiu, Ke Xu, et al.
Pathological Gambling and Associated Drug and Alcohol Abuse, Emotion Regulation, and Anxious-Depressive Symptomatology

Background and aims Pathological gambling is associated with comorbid disorders, such as anxiety, depression, and drug and alcohol abuse. Difficulties of emotion regulation may be one of the factors related to the presence of addictive disorders, along with comorbid symptomatology in pathological gamblers. Therefore, the aim of this study was to evaluate the difficulties of emotion regulation, drug and alcohol abuse, and anxious and depressive symptomatology in pathological gamblers, and the mediating role of difficulties of emotion regulation between anxiety and pathological gambling. Methods The study sample included 167 male pathological gamblers (mean age = 39.29 years) and 107 non-gamblers (mean age = 33.43 years). Pathological gambling (SOGS), difficulties of emotion regulation (DERS), drug and alcohol abuse (MUTICAGE CAD-4), and anxious and depressive symptomatology (SA-45) were measured. Student’s t, Pearson’s r, stepwise multiple linear regression and multiple mediation analyses were conducted. The study was approved by an Investigational Review Board. Results Relative to non-gamblers, pathological gamblers exhibited greater difficulties of emotion regulation, as well as more anxiety, depression, and drug abuse. Moreover, pathological gambling correlated with emotion regulation difficulties, anxiety, depression, and drug abuse. Besides, emotion regulation difficulties correlated with and predicted pathological gambling, drug and alcohol abuse, and anxious and depressive symptomatology. Finally, emotion regulation difficulties mediated the relationship between anxiety and pathological gambling controlling the effect of age, both when controlling and not controlling for the effect of other abuses. Discussion and conclusions These results suggest that difficulties of emotion regulation may provide new keys to understanding and treating pathological gambling and comorbid disorders.
Real time analysis of current transport protocols in high loss networks

Internet real-time and reliable transmission is demanded in many applications. Existing transport protocols is hard to meet above requirements. For example, RTP is used in real-time applications, but it is not reliable. In high loss and delay networks, TCP is hard to provide real-time transmission. On the contrary, UDP is not reliable protocol. In this paper, the property of real-time is analysed which focused on TCP and UDP. Transmission delay and average transmission delay are employed to express the real-time. It is clear that low average transmission delay indicates better real-time. In our simulation, we focus on TCP about its real-time in high loss and delay networks. In addition, goodput is also important for users. High goodput and real-time transport protocol is desired for a number of applications.
PSA Oligoepitope Peptide Prostate-Specific Antigen (PSA) Employing a Lymphocyte Lines Directed Against Generation of Human Cytolytic T

Prostate-speciﬁc Ag (PSA), which is expressed in a majority of prostate cancers, is a potential target for speciﬁc immunotherapy. Previous studies have shown that two 10-mer PSA peptides (designated PSA-1 and PSA-3) selected to conform to human HLA class I-A2 motifs can elicit CTL responses in vitro. A longer PSA peptide (30-mer) designated PSA-OP (oligoepitope peptide), which contains both the PSA-1 and PSA-3 HLA-A2 epitopes and an additional potential CTL epitope (designated PSA-9) for the HLA-class I-A3 allele, was investigated for the ability to induce cytotoxic T cell activity. T cell lines from different HLA-A2 and HLA-A3 donors were established by in vitro stimulation with PSA-OP; the CTL lines lysed PSA-OP as well as PSA-1- or PSA-3-pulsed C1R-A2 cells, and PSA-OP and PSA-9-pulsed C1R-A3 cells, respectively. The CTL lines derived from the PSA-OP peptide also lysed PSA-positive prostate cancer cells. PSA-OP-derived T cell lines also lysed recombinant vaccinia-PSA-infected targets but not targets infected with wild-type vaccinia. PSA-OP did not bind HLA-A2 and HLA-A3 molecules. The decrease in cytotoxicity in the presence of protease inhibitors suggests that the PSA-OP is cleaved into shorter peptides, which in turn can interact with HLA-class I molecules and, as a consequence, induce CTL-mediated lysis. We have also demonstrated that it is possible to induce CTL responses in HLA-A2.1/K b transgenic mice by immunization
Surface-plasmon enhanced Raman scattering of DNA molecules on regular arrays of modified gold nanoparticles

We performed surface-plasmon enhanced Raman scattering (SERS) studies of a DNA monolayer on chemically modified Au nanoparticle arrays. Drastic enhancement of Raman signal from DNA molecules was observed on the optimized templates that were prepared by using electron-beam lithography followed by chemical modification. We observed that Raman signal of DNA molecules was enhanced when the surface plasmons in the closely-spaced Au nanoparticles were resonantly excited. Our results suggest that the artificial generation of spatially controlled hot spots for SERS can be achieved by this technique.
Power efficient topology control in wireless ad hoc networks

In the wireless ad hoc networks, for prolonging the communication duration of the nodes, the transmission power is required to be minimized to conserve the limited battery life. In addition, for the wireless ad hoc networks to be applicable, the networks are required to he connected. Unfortunately, the two requirements are against each other. In this paper, by analyzing the probability of isolated node, we obtain the relationships between transmission range, service area and network connectedness. Furthermore, we propose a generalized (N,B) wireless ad hoc network model to investigate the impact of boundary nodes on the network connectivity, equivalent service area and average node degree.
Emotion perception in pre-kindergarten school children at Central Institute for the Deaf

The purpose of this study is to assess the ability of Pre-kindergarten (pre-k) students with both normal hearing (NH) and impaired hearing (HI) to identify emotion in speech through audition only. A secondary purpose is to assess whether a listener's familiarity with a speaker's voice has an effect on his/her ability to identify the emotion of the talker.
Tracing the production and degradation of autochthonous fractions of dissolved organic matter by fluorescence analysis

We present the results of a mesocosm experiment investigating the production and utilization of autochthonous dissolved organic matter (DOM) by the plankton community under different inorganic nutrient regimes. Fluorescence spectroscopy combined with parallel factor analysis was applied to study the dynamics of autochthonous DOM. Seven independent fluorescent fractions were identified, differing in their spectral characteristics, production rates, and sensitivity to photochemical and microbial degradation processes. Five different humic fractions, a marine protein, and a peptide fluorescence were found. The five humic fractions were produced microbially, with the greatest production occurring under combined Si‐ and P‐limiting conditions. The two proteinaceous fractions were produced during exponential growth of phytoplankton, irrespective of biomass composition. Photodegradation was an important sink for the microbially derived humic material, and the marine protein material was susceptible to both photoand microbial degradation.
Implementation of real time channel based spectrum monitoring for 2.4 GHz ISM band

In communication applications, frequency spectrum management has become an important issue due to rapid increase in the number of devices that use the limited frequency spectrum. Efficient spectrum management is a necessity due to resource scarcity. Cognitive radios are emerged as one of the most prominent for solutions for this problem. Recently, the frequency spectrum management implementations of cognitive radios has increased. In this study, channel based spectrum monitoring of 2.4 GHz ISM band is implemented using energy detection method and also software defined radio technology. The channel based usage density of ISM band is shown consistently as the outcome of this study.
Image super-resolution reconstruction based on adaptive interpolation norm regularization

An image super-resolution reconstruction algorithm is proposed based on adaptive interpolation norm regularization, which can not only preserve more details near image edges than Tikhonov regularization, but also efficiently alleviate the staircasing of total variation regularization on flat regions. Furthermore, we propose the use of regularization functional instead of a constant regularization parameter. The regularization functional is defined in terms of the restored image at each iteration step, therefore allowing for the simultaneous determination of its value and the restoration of the degraded image. The iteration scheme, convergence and control function are thoroughly studied. Experimental results demonstrate the power of the proposed method.
Real-time multimedia over ATM: RMOA

RMOA is a new ATM Forum standard addressing the transport of H.323 VoIP traffic over ATM-based Internet backbones. It defines a new H.323 gateway devised to carry H.323 real-time media streams by taking advantage of the quality of service features of ATM. The approach is extremely efficient in that it reduces the protocol overhead on the ATM transport.
Design of the dynamic stability properties of the collective behavior of articulated bipeds

The control of the collective behavior of multiple interacting agents is a challenging problem in robotics and autonomous systems design. Such behaviors can be characterized by the dynamic interaction between multiple locomoting bipeds with highly nonlinear articulation dynamics. The analysis and design of the stability properties of such complex multi-component systems is a largely unsolved problem. We discuss a first approach to this problem exploiting concepts from Contraction Theory, a recent framework for the analysis of the stability of complex nonlinear dynamical systems. We demonstrate the application of this framework to groups of humanoid agents interacting collectively in different ways, requiring different types of control rules for their propagation in space and their articulation dynamics. We illustrate the framework based on a learning-based realtime-capable architecture for simulation of the kinematics of propagating bipeds, suitable for the reproduction of natural locomotion trajectories and walking styles. Exploiting central theorems from Contraction Theory and nonlinear control, we derive conditions guaranteeing the global exponential stability of the formation of the coordinated multiagent behavior. In addition, we demonstrate that the same approach permits to derive bounds that guarantee minimum convergence speeds for the formation of ordered states for collective behaviors of multiple humanoid agents.
Soluble Vascular Cell Adhesion Molecule-1 (sVCAM-1) Is Elevated in Bronchoalveolar Lavage Fluid of Patients with Acute Respiratory Distress Syndrome

Introduction Pulmonary vascular endothelial activation has been implicated in acute respiratory distress syndrome (ARDS), yet little is known about the presence and role of endothelial activation markers in the alveolar space in ARDS. We hypothesized that endothelial activation biomarkers would be differentially expressed in bronchoalveolar lavage fluid from patients with ARDS compared with healthy volunteers, and that biomarker concentrations would be associated with ARDS severity. Methods We performed a cross-sectional analysis of data from 26 intubated patients with ARDS undergoing evaluation for clinically suspected ventilator-associated pneumonia and five healthy volunteers. Patients underwent bronchoalveolar lavage a median of five days after intubation. Healthy volunteers also underwent bronchoalveolar lavage. Endothelial activation biomarkers (soluble vascular cell adhesion molecule-1 [sVCAM-1], soluble endothelial selectin [sESEL], angiopoietin-1 [Ang-1] and angiopoietin-2 [Ang-2]) were measured in bronchoalveolar lavage fluid. Clinically suspected ventilator-associated pneumonia was confirmed with microbiologic culture data. Results Patients with ARDS had significantly higher median sVCAM-1 concentrations in the bronchoalveolar lavage fluid compared with healthy volunteers (985 vs 119 pg/mL, p = 0.03). Additionally, there was a trend toward greater bronchoalveolar lavage fluid sVCAM-1 concentrations among patients with moderate/severe compared to mild ARDS (1395 vs 209 pg/mL, p = 0.06). We did not detect significant differences in bronchoalveolar lavage fluid levels of sESEL, Ang-1 or Ang-2 between patients with ARDS and healthy volunteers. Median bronchoalveolar lavage fluid biomarker levels did not differ between patients with and without microbiologically-confirmed ventilator-associated pneumonia. Conclusions sVCAM-1 concentrations were significantly higher in the bronchoalveolar lavage fluid of patients with ARDS compared to healthy controls, and tended to be higher in moderate/severe ARDS compared to mild ARDS. Our findings add to the growing evidence supporting the concept that endothelial activation plays an important mechanistic role in the pathogenesis of ARDS. Further studies are necessary to characterize the role and/or clinical significance of sVCAM-1 and other endothelial activation markers present in the alveolar space in ARDS.
Unsupervised image change detection means based on 2-D entropy

In this paper, a novel image change detection means based on 2-D histogram formed by pixel gray levels and the local average gray levels is proposed. First, the 2-D histogram is segmented by a line passing through the diagonal of 2-D histogram in a certain direction. Second, the improved 2-D entropy is defined to acquire the optimal segmentation direction and the optimal threshold. And the 2-D histogram is segmented into unchanged region and change region. Then the change area is detected based on the change region of 2-D histogram. Finally, the change detection means is compared to traditional means Theoretical analysis and experiment result show that this algorithm is more accurate on detection precision and faster on detection speed.
Using Option Models to Evaluate Investment Decisions in Cross Training Programs

We propose using a real options framework to quantify the financial value of cross training. We model the investment decision in cross training as a series of European call options with the same exercise price but with different maturity dates. We use the Black-Scholes formula and the binomial tree approach to find the value of having the option to cross train. A case study shows the application of our proposed model to value the option of cross training in an environment where the price of the product is stochastic. We also demonstrate the advantage of using the option valuation method as opposed to the traditional discounted cash flow analysis to quantify the value of cross training.
Comparison of sequence matching techniques for video copy detection

Video copy detection is a complementary approach to watermarking. As opposed to watermarking, which relies on inserting a distinct pattern into the video stream, video copy detection techniques match content-based signatures to detect copies of video. Existing typical content-based copy detection schemes have relied on image matching. This paper proposes two new sequence-matching techniques for copy detection and compares the performance with one of the existing techniques. Motion, intensity and color-based signatures are compared in the context of copy detection. Results are reported on detecting copies of movie clips.
Effect of Peaches, Pears and Green Tea on Plasma Lipids Profile and Antioxidant Content in Rats Fed High Sucrose Diet

The beneficial effects of feeding syrup of peaches and pears (peel and pulp) & green tea on the restoration of the changes produced by feeding high sucrose diet on plasma lipid profile, plasma antioxidant activity, and antioxidant enzymes in red blood cells (RBC) hemolysate were studied. High sucrose diet induced hyperlipidemia as manifested by significant (P ≤ 0.05) increases in the levels of cholesterol, triglycerides (TG) and low density lipoproteins (LDL) in plasma from 103.33 ± 1.8, 61.17 ± 0.48 and 26.6 ± 5.01 mg/dl to 136.67 ± 2.2, 81.3 ± 1.5 and 64.6 ± 6.5 mg/dl respectively. The high density lipoproteins (HDL) level was not significantly affected. TG levels in heart muscles increased significantly P ≤ 0.05 from the level of 194.14 ± 4.35 μg/g in the negative control to 269.72 ± 5.39 μg/g. Administration of fruits syrup and green tea resulted in a significant variable reduction in the elevated levels of cholesterol, TG and LDL and TG in the heart. Administration of sucrose resulted also in elevation of Malondialdehyde (MDA) in plasma from 5.06 ± 0.18 in the negative control to 14.81 ± 0.48 μmol/L in the positive control. This was also accompanied by reduction in the activities of supper oxide dismutase (SOD), glutathione peroxidase (GSH-Px), catalase (CAT) and a decrease in the concentration of reduced glutathione (GSH) in plasma, indicating lipid peroxidation. The activities of SOD, GSH-Px, CAT in the negative control were 8.96 ± 0.19, 315.67 ± 5.86, 209 ± 2.18 U/gHb respectively and were reduced significantly in the positive control to 4.7 ± 0.2, 273.83 ± 7.85, 207 ± 2.53 U/g Hb. There was a significant decrease in the level of total antioxidant status (TAS) in plasma from 1.45 ± 0.09 to 0.88 ± 0.09 nmol/L. However, no statistically significant changes were noticed in the concentrations of plasma total proteins and albumin. Intake of syrup of peaches and pears (peel and pulp) & green tea increased the level of TAS and GSH and decreased the level of LDL. The treatment also decreased significantly (P ≤ 0.05) the levels of plasma cholesterol, TG and heart TG levels. The activities of SOD and GSH-Px were increased following the treatment. It can be concluded that syrup of peaches and pears (peel and pulp) & green tea modulate lipid metabolism and enhance antioxidant status and in this respect green tea produced the best effect followed by peels of pears and peaches. The beneficial effect produced by fruits syrup and green tea may be due to their contents of phytochemicals.