Miracle-dz/UniFAR-FTUs huggingface dataset:
Estimation of InSAR baseline based on the Frequency Shift Theory

Baseline is a very important parameter in SAR interferometry (InSAR) processing and applications, and it is crucial in InSAR system design, data processing and error analysis, and then straightly impacts the generation and quality of DEM from interferogram, so how to get the high precision baseline becomes the important problem of airborne InSAR. In this paper, a new quick method of baseline estimation was proposed, which was based on the frequency shift theory for estimating the perpendicular component of the baseline. The result is validated with the SIR-C/X-SAR data over the Tienshan area of china on October 7 and 8, 1994
RNA Virus Reassortment: An Evolutionary Mechanism for Host Jumps and Immune Evasion

Reassortment is an evolutionary mechanism of segmented RNA viruses that plays an important but ill-defined role in virus emergence and interspecies transmission. Recent experimental studies have greatly enhanced our understanding of the cellular mechanisms of reassortment within a host cell. Our purpose here is to offer a brief introduction on the role of reassortment in segmented RNA virus evolution, explain the host cellular mechanisms of reassortment, and provide a synthesis of recent experimental findings and methodological developments. While we focus our discussion on influenza viruses, wherein most of the studies on reassortment have been carried out, the concepts presented are broadly applicable to other multipartite genomes.
Cluster Radio Relics as a Tracer of Shock Waves of the Large-Scale Structure Formation

We present evidence for the existence of shock waves caused by the formation of the large-scale structure. In some clusters of galaxies peripherally located sources of extended diffuse radio emission exist, the so-called cluster radio relics. They have steep radio spectra but no apparent cutoff, as old remnants of radio galaxies usually have. Therefore particle acceleration has to take place within them. We propose that shock structures of the cosmological large-scale matter flows are responsible for the acceleration of relativistic electrons: cluster accretion shocks and bow shocks of merger events. We develop a theory of radio plasma having traversed these shocks and compare it to observational data of nine radio relics (0038-096, 0917+75, 1140+203, 1253+275, 1712+64, 1706+78, 2006-56, 2010-57, 1401-33) and their host clusters (A85, A786, A1367, Coma, A2255, A2256, A3667, S753). The necessary accretion power, the spectral index of the radio spectrum, the acceleration efficiency of the shock, the diffusion coefficient in the post-shock region, and the predicted radio polarization in all of our examples fit into a coherent interpretation of the observational data. Since polarization measurements are available only for four sources, the predictions of our theory can be independently checked using other examples. The predicted values of the shock compression ratio, density and temperature of the infalling gas, magnetic field strength of the shocked and unshocked radio plasma are discussed within the frame of structure formation theory.
Contextual Differences in Substance Use for Rural Appalachian Treatment-Seeking Women

Objective: To examine differences in substance use among a sample of women entering treatment from rural Appalachian and non-Appalachian areas. Participants: A total of 2,786 women participating in state-funded substance abuse treatment programs statewide. Measures: Substance use measures were based on the SAMHSA CSAT Government Performance and Results Act (GPRA) gathering information on lifetime and past 12-month use of alcohol, marijuana, opiates, sedatives/tranquilizers, cocaine, and stimulants. Results: Women entering treatment in rural Appalachia had disproportionately high rates of opiate and sedative/tranquilizer use while methamphetamine, cocaine, marijuana, and alcohol were more prevalent for women in non-Appalachian areas. Conclusions: Women entering treatment in rural Appalachia were significantly more likely to report opiate and sedative/tranquilizer use compared to non-Appalachian women. In order to begin to understand the elevated rates of prescription drug abuse in rural Appalachian Kentucky, substance use must be considered within the context of demographic, geographic, social, and economic conditions of the region.
Climate change, tree pollination and conservation in the tropics: a research agenda beyond IPBES

Tree‐pollinator interactions are important ecosystem services that are threatened by global warming and climate change. Very few investigations have focused on fruit‐tree pollination interactions in the tropics. In this paper, we analyze knowledge gaps proposed by the Intergovernmental Platform on Biodiversity and Ecosystem Services (IPBES) with special reference to the tropics and associated with (1) the effects of climate change on plant‐pollinator interactions and (2) pollinator diversity and population attributes within the context of nature conservation. WIREs Clim Change 2018, 9:e502. doi: 10.1002/wcc.502
HEREDITARY DEGENERATION OF THE RAT RETINA

cataract than the retinal lesion itself. This point is being more fully investigated. The cataract is not due to a disturbance in the blood supply to the eye; the vessels of the retina and choroid were found to be healthy at the time of onset of the lens changes; the iris and ciliary body were found to be normal. Nor is it likely that the cataract results from some general metabolic disturbance, since the two eyes of an animal are not always affected to the same extent. The animals appear to be healthy and their diet is adequate in all known dietary essentials. It is interesting to note that Jess (1925) described an hereditary and congenital cataract occurring in a colony of white rats. Ihirty-four per cent. of the 300 eyes examined by him were affected. The cataract consisted of granular opacities in the anterior cortex; the number, size and density of these opacities varied greatly, often appearing as a thick " bee-swarm " in an otherwise clear lens. From this description it appears that Jess's cataract is different from the one described here.
Recently occluded intracranial and extracranial carotid arteries. Relevance of the unstable atherosclerotic plaque.

BACKGROUND AND PURPOSE It is now widely accepted that thrombotic coronary artery occlusion usually follows rupture of an unstable atherosclerotic plaque. The significance of such instability in arteries supplying the brain is less well appreciated. We therefore describe the clinical and pathological features of recent, symptomatic internal carotid artery occlusion to examine the pathogenetic role of plaque instability at both extracranial and intracranial sites. METHODS Cases were selected from a consecutive series of 188 adult neuropathology autopsies. In 90 of these, the principal neuropathological abnormality was cerebral infarction, in 14 cases due to recent occlusion of 1 or more segments of the internal carotid artery. In each case, a full systemic, cardiovascular, and neuropathological autopsy was performed. Plaque instability was assessed by the presence or absence of a large, necrotic, lipid core; a thin, fibrous cap; and superficial inflammation. RESULTS Of the 14 cases, 3 showed extracranial (carotid sinus), 7 intracranial, and 4 both extracranial and intracranial carotid artery occlusion. In 6 of the 7 occluded carotid sinuses, thrombus overlay an ulcerated, unstable, atherosclerotic plaque. In 1 extracranial and all 11 intracranial occlusions, there was either no atheroma or a mildly stenotic, stable, fibrous plaque, and in these cases, the cause of occlusion was embolism (8 cases), giant-cell arteritis (1 case), and unknown (3 cases). CONCLUSIONS Coronary-type rupture of an unstable atherosclerotic plaque is the usual cause of fatal occlusion of the carotid sinus, but other causes usually underlie intracranial carotid occlusion. The nature and consequences of intracranial atherosclerosis require further study.
Effects of interactivity and 3D-motion on mental rotation brain activity in an immersive virtual environment

The combination of virtual reality (VR) and brain measurements is a promising development of HCI, but the maturation of this paradigm requires more knowledge about how brain activity is influenced by parameters of VR applications. To this end we investigate the influence of two prominent VR parameters, 3d-motion and interactivity, while brain activity is measured for a mental rotation task, using functional MRI (fMRI). A mental rotation network of brain areas is identified, matching previous results. The addition of interactivity increases the activation in core areas of this network, with more profound effects in frontal and preparatory motor areas. The increases from 3d-motion are restricted to primarily visual areas. We relate these effects to emerging theories of cognition and potential applications for brain-computer interfaces (BCIs). Our results demonstrate one way to provoke increased activity in task-relevant areas, making it easier to detect and use for adaptation and development of HCI.
Relationships between hepatic neoplasms and related lesions and exposure to toxic chemicals in marine fish from the U.S. West Coast.

English sole (Parophrys vetulus) inhabiting polluted waterways and embayments of Puget Sound, Washington, are affected with a variety of multiple, co-occurring idiopathic hepatic lesions, including unique degenerative conditions, putatively preneoplastic foci of cellular alteration, and neoplasms. Results of a statistical analysis of the patterns of co-occurrence of these lesions in wild English sole are consistent with the concept that these lesions represent morphologically identifiable steps forming a sequence of progression ultimately leading to the development of hepatic neoplasms. This progressive sequence parallels the pattern identified in experimental models of chemically induced hepatocarcinogenesis in rodents. The rationale for the hypothesis that these lesions in wild English sole can be caused by exposure to certain hepatoxic and hepatocarcinogenic xenobiotic compounds in the marine environment is based on the demonstration of significant and consistent statistical associations between levels of aromatic hydrocarbons (AHs) in sediment and prevalences of these idiopathic liver lesions; a significant contribution by sediment AHs to the variability in hepatic neoplasm prevalence in a logistic regression model; significantly increased probabilities for several idiopathic lesions in sole from chemically contaminated sites in Puget Sound; significant correlations between uptake of polycyclic aromatic hydrocarbons, as measured by levels of fluorescent metabolites of aromatic compounds in bile of sole, and prevalences of several hepatic lesion types; and experimental induction of unique degenerative, proliferative, and putatively preneoplastic focal lesions in English sole injected with either benzo(a)pyrene or a polycyclic aromatic hydrocarbons (PAH) enriched fraction of an extract from a contaminated urban sediment from Puget Sound. (ABSTRACT TRUNCATED AT 250 WORDS)
Risk of myocardial infarction in patients with psoriasis.

CONTEXT Psoriasis is the most common T-helper cell type 1 (T(H)1) immunological disease. Evidence has linked T(H)1 diseases to myocardial infarction (MI). Psoriasis has been associated with cardiovascular diseases, but has only been investigated in hospital-based studies that did not control for major cardiovascular risk factors. OBJECTIVE To determine if within a population-based cohort psoriasis is an independent risk factor for MI when controlling for major cardiovascular risk factors. DESIGN, SETTING, AND PATIENTS A prospective, population-based cohort study in the United Kingdom of patients with psoriasis aged 20 to 90 years, comparing outcomes among patients with and without a diagnosis of psoriasis. Data were collected by general practitioners as part of the patient's medical record and stored in the General Practice Research Database between 1987 and 2002, with a mean follow-up of 5.4 years. Adjustments were made for hypertension, diabetes, history of myocardial infarction, hyperlipidemia, age, sex, smoking, and body mass index. Patients with psoriasis were classified as severe if they ever received a systemic therapy. Up to 5 controls without psoriasis were randomly selected from the same practices and start dates as the patients with psoriasis. A total of 556,995 control patients and patients with mild (n = 127,139) and severe psoriasis (n = 3837) were identified. MAIN OUTCOME MEASURE Incident MI. RESULTS There were 11,194 MIs (2.0%) within the control population and 2319 (1.8%) and 112 (2.9%) MIs within the mild and severe psoriasis groups, respectively. The incidences per 1000 person-years for control patients and patients with mild and severe psoriasis were 3.58 (95% confidence interval [CI], 3.52-3.65), 4.04 (95% CI, 3.88-4.21), and 5.13 (95% CI, 4.22-6.17), respectively. Patients with psoriasis had an increased adjusted relative risk (RR) for MI that varied by age. For example, for a 30-year-old patient with mild or severe psoriasis, the adjusted RR of having an MI is 1.29 (95% CI, 1.14-1.46) and 3.10 (95% CI, 1.98-4.86), respectively. For a 60-year-old patient with mild or severe psoriasis, the adjusted RR of having an MI is 1.08 (95% CI, 1.03-1.13) and 1.36 (95% CI, 1.13-1.64), respectively. CONCLUSIONS Psoriasis may confer an independent risk of MI. The RR was greatest in young patients with severe psoriasis.
Persistent infection of K562 cells by encephalomyocarditis virus

Infection of human erythroleukemic K562 cells by encephalomyocarditis virus readily resulted in establishment of persistently infected cultures. In contrast to the usual typical lytic infection by encephalomyocarditis virus, in which trypan blue staining of cells reaches close to 100% by about 15 h postinfection, K562 cell cultures required 3 to 4 days postinfection to reach a maximum of about 80 to 90% cell staining. The proportion of K562 cells taking up stain gradually decreased to about 10% of those present by about 13 days postinfection; during this time, virus yield per day measured by either plaque or hemagglutination titration fell about 10-fold. The decrease in percent staining was followed by waves of increased staining accompanied by increased virus production. Virus-producing cultures were maintained for over 3 months. Evolution of both virus and cells accompanied establishment of persistence in that plaque size changed from about 7 mm in diameter for the original virus to less than 1.5 mm by day 20 postinfection and most of the cells cloned from persistently infected cultures were resistant to superinfection with the original virus. Resistance was due, at least in part, to reduced virus attachment in that binding of 3H-labeled virus to cloned resistant cells was about 2% of that to uninfected cells.
Hunter-Gatherer Mobility Strategies in the High Andes of Northern Chile during the Late Pleistocene-Early Holocene Transition (ca. 11,500–9500 CAL B.P.)

ABSTRACT The high Andes of western South America feature extreme ecological conditions that impose important physiological constraints on humans including high-elevation hypoxia and cold stress. This leads to questions regarding how these environments were colonized by the first waves of humans that reached them during the late Pleistocene. Based on previous research, and aided by human behavioral ecology principles, we assess hunter-gatherer behavioral strategies in the Andean highlands during the late Pleistocene and early Holocene. Specifically, we formulate three mobility strategies and their archaeological expectations and test these using technological and subsistence evidence from the six earliest well-dated highland sites in northern Chile. Our results suggest that all of the studied sites were temporarily occupied for hunting, processing animals, and toolkit maintenance. The sites also exhibit shared technological features within a curatorial strategy albeit with different occupation intensities. From this evidence, we infer that the initial occupations of the highlands were logistical and probably facilitated by increased local resource availability during a period of environmental amelioration.
Mouse Conventional Dendritic Cells Can be Universally Classified Based on the Mutually Exclusive Expression of XCR1 and SIRPα

Since the identification of mouse dendritic cells (DC) in the early 70s, all attempts to consistently classify the identified functional DC subpopulations according to their surface molecule expression failed. In the absence of DC lineage markers, a great variety of non-congruent surface molecules were used instead. Recent advances in the understanding of the involvement of transcription factors in the differentiation of DC subpopulations, together with the identification of a lineage marker for cross-presenting DC, have now allowed to establish a consistent and unified DC classification in the mouse. We demonstrate in the present article that all conventional DC in the mouse can be universally subdivided into either XCR1+ cross-presenting DC or SIRPα+ DC, irrespective of their activation status. This advancement will greatly facilitate future work on the biology of mouse DC. We discuss this new classification in view of current DC classification systems in the mouse and the human.
Omega-3 and Omega-6 Polyunsaturated Fatty Acid Levels and Correlations with Symptoms in Children with Attention Deficit Hyperactivity Disorder, Autistic Spectrum Disorder and Typically Developing Controls

Background There is evidence that children with Attention Deficit Hyperactivity Disorder (ADHD) and Autistic Spectrum Disorder (ASD) have lower omega-3 polyunsaturated fatty acid (n-3 PUFA) levels compared with controls and conflicting evidence regarding omega-6 (n-6) PUFA levels. Objectives This study investigated whether erythrocyte n-3 PUFAs eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) were lower and n-6 PUFA arachidonic acid (AA) higher in children with ADHD, ASD and controls, and whether lower n-3 and higher n-6 PUFAs correlated with poorer scores on the Australian Twin Behaviour Rating Scale (ATBRS; ADHD symptoms) and Test of Variable Attention (TOVA) in children with ADHD, and Childhood Autism Rating Scale (CARS) in children with ASD. Methods Assessments and blood samples of 565 children aged 3–17 years with ADHD (n = 401), ASD (n = 85) or controls (n = 79) were analysed. One-way ANOVAs with Tukey’s post-hoc analysis investigated differences in PUFA levels between groups and Pearson’s correlations investigated correlations between PUFA levels and ATBRS, TOVA and CARS scores. Results Children with ADHD and ASD had lower DHA, EPA and AA, higher AA/EPA ratio and lower n-3/n-6 than controls (P<0.001 except AA between ADHD and controls: P = 0.047). Children with ASD had lower DHA, EPA and AA than children with ADHD (P<0.001 for all comparisons). ATBRS scores correlated negatively with EPA (r = -.294, P<0.001), DHA (r = -.424, P<0.001), n-3/n-6 (r = -.477, P<0.001) and positively with AA/EPA (r = .222, P <.01). TOVA scores correlated positively with DHA (r = .610, P<0.001), EPA (r = .418, P<0.001) AA (r = .199, P<0.001), and n-3/n-6 (r = .509, P<0.001) and negatively with AA/EPA (r = -.243, P<0.001). CARS scores correlated significantly with DHA (r = .328, P = 0.002), EPA (r = -.225, P = 0.038) and AA (r = .251, P = 0.021). Conclusions Children with ADHD and ASD had low levels of EPA, DHA and AA and high ratio of n-6/n-3 PUFAs and these correlated significantly with symptoms. Future research should further investigate abnormal fatty acid metabolism in these disorders.
An Integrated Corporate Governance Framework and Financial Performance in South African Listed Corporations

This paper investigates the relationship between an integrated corporate governance (CG) index and financial performance using a sample of 169 South African (SA) listed corporations between 2002 and 2007. We find a statistically significant and positive association between a broad set of good CG practices and financial performance. In a series of sensitivity analyses, we find that our results are robust to endogeneity, different financial performance proxies, alternative CG weighting scheme and firm-level fixed-effects. We further distinctively examine the link between complying with SA context specific stakeholder CG provisions and financial performance. In line with political cost and resource dependence theories, our results reveal a statistically significant and positive nexus between compliance with stakeholder CG provisions and financial performance.
Physical and logical topology slicing through SDN

This paper demonstrates the physical and logical topological slicing in computer networks through Software Defined Networks (SDN) with the added benefit of data privacy. To deal with the complex requirements of the modern networks, a sudden re-configuration of a network is often required. Modern applications require the configuration of networks on a fly and according to dynamically changing requirements, but the conventional solutions need to configure each and every device locally. The real time requirements are dynamic and the conventional network configuration is static in nature. SDN provides a better option by enabling the programmable interfaces on network hardware and a centralized control. Based on an emulated topology, this paper presents the physical and logical topology slicing under a centralised control by using SDN with no need of the local configuration of network elements.
Adaptive Cache Management for Energy-Efficient GPU Computing

With the SIMT execution model, GPUs can hide memory latency through massive multithreading for many applications that have regular memory access patterns. To support applications with irregular memory access patterns, cache hierarchies have been introduced to GPU architectures to capture temporal and spatial locality and mitigate the effect of irregular accesses. However, GPU caches exhibit poor efficiency due to the mismatch of the throughput-oriented execution model and its cache hierarchy design, which limits system performance and energy-efficiency. The massive amount of memory requests generated by GPU scause cache contention and resource congestion. Existing CPUcache management policies that are designed for multicoresystems, can be suboptimal when directly applied to GPUcaches. We propose a specialized cache management policy for GPGPUs. The cache hierarchy is protected from contention by the bypass policy based on reuse distance. Contention and resource congestion are detected at runtime. To avoid oversaturatingon-chip resources, the bypass policy is coordinated with warp throttling to dynamically control the active number of warps. We also propose a simple predictor to dynamically estimate the optimal number of active warps that can take full advantage of the cache space and on-chip resources. Experimental results show that cache efficiency is significantly improved and on-chip resources are better utilized for cache sensitive benchmarks. This results in a harmonic mean IPC improvement of 74% and 17% (maximum 661% and 44% IPCimprovement), compared to the baseline GPU architecture and optimal static warp throttling, respectively.