Miracle-dz/UniFAR-FTUs huggingface dataset:
From Fruit Waste to Medical Insight: The Comprehensive Role of Watermelon Rind Extract on Renal Adenocarcinoma Cellular and Transcriptomic Dynamics

Cancer researchers are fascinated by the chemistry of diverse natural products that show exciting potential as anticancer agents. In this study, we aimed to investigate the anticancer properties of watermelon rind extract (WRE) by examining its effects on cell proliferation, apoptosis, senescence, and global gene expression in human renal cell adenocarcinoma cells (HRAC-769-P) in vitro. Our metabolome data analysis of WRE exhibited untargeted phyto-constituents and targeted citrulline (22.29 µg/mg). HRAC-769-P cells were cultured in RPMI-1640 media and treated with 22.4, 44.8, 67.2, 88.6, 112, 134.4, and 156.8 mg·mL−1 for 24, 48, and 72 h. At 24 h after treatment, (88.6 mg·mL−1 of WRE) cell proliferation significantly reduced, more than 34% compared with the control. Cell viability decreased 48 and 72 h after treatment to 45% and 37%, respectively. We also examined poly caspase, SA-beta-galactosidase (SA-beta-gal), and wound healing activities using WRE. All treatments induced an early poly caspase response and a significant reduction in cell migration. Further, we analyzed the transcript profile of the cells grown at 44.8 mg·mL−1 of WRE after 6 h using RNA sequencing (RNAseq) analysis. We identified 186 differentially expressed genes (DEGs), including 149 upregulated genes and 37 downregulated genes, in cells treated with WRE compared with the control. The differentially expressed genes were associated with NF-Kappa B signaling and TNF pathways. Crucial apoptosis-related genes such as BMF, NPTX1, NFKBIA, NFKBIE, and NFKBID might induce intrinsic and extrinsic apoptosis. Another possible mechanism is a high quantity of citrulline may lead to induction of apoptosis by the production of increased nitric oxide. Hence, our study suggests the potential anticancer properties of WRE and provides insights into its effects on cellular processes and gene expression in HRAC-769-P cells.
Contrasting Impacts of Agricultural Intensification and Urbanization on Lake Phosphorus Cycling and Implications for Managing Eutrophication

Sediment core and water quality data, together with historical information on land use/land cover (LULC), were used to reconstruct changes in phosphorus (P) loading and cycling in Lake Wilcox, Ontario, Canada, since the early 1920s. After first being cleared for farming, the originally forested watershed subsequently underwent urbanization. The large increase in P loading accompanying agricultural intensification after World War II caused the eutrophication of the lake. However, improved soil conservation since the 1980s and urban stormwater management since the 1990s have brought watershed P loading and sediment accumulation down to levels comparable to the early 1900s. Yet, the lake continues to exhibit eutrophication‐like symptoms, especially the intensification of hypoxia in the hypolimnion. Post‐2000 water quality data indicate that the latter is not driven by external P loading from the watershed, but rather by rapid salinization that strengthens the lake's summer stratification and enhances internal P loading. Salinization is caused by the increasing application of deicing agents in the expanding urban area. Curbing salt inputs will therefore be essential to restore the lake. Overall, our results provide new insights into the shifts in lake biogeochemistry associated with LULC changes and the implementation of best management practices. The approaches and findings of our case study have broad applicability for the large number of freshwater ecosystems worldwide that are experiencing salinization.
Vibration Problems associated with the Helicopter

The Chairman, in introducing the Author, said that the occasion was a very auspicious one, in that a paper was being presented by one of the founder members of the Association at a Joint Meeting with the Royal Aeronautical Society, with which the Association maintained the closest of links On behalf of the Association he welcomed the fact that a joint meeting was being held, and he welcomed those members of the Society who were present to hear a paper and discussion on a specialised helicopter subject In particular he welcomed the President of the Royal Aeronautical Society, Mr E T Jones
Long recurrence records from the Wasatch fault zone, Utah

4 Introduction.5 Acknowledgements.5 Geologic and Geomorphic Setting of the Megatrench Site . 6 Location and Local geology.6 Site Geomorphology . 7 Previous Trenching Study of Woodward-Clyde Consultants (1979) . 8 Structure.9 Overview.9 Fault Zone F1.9 Fault Zone F2.12 Fault Zone F3.12 Fault Zone F4.12 Stratigraphy, Soils, and Geochronology . 12 Mapping Conventions.13 Lacustrine Stratigraphy.13 Soils . 16 Geochronology.16 Loess . 17 Alluvial Units.17 Colluvial Units . 18 Colluvium in the Eastern and Central Parts of the Trench.19 Colluvium in the Western End of the Trench . 20 Soil Profile Development.21 Post-Trenching Geophysics . 24 Sequence of Faulting Events.25 Overview.25 Fault Zone F1.25 Fault Zone F2.28 Fault Zone F3.28 Fault Zone F4.28 Composite Retrodeformation Sequence of Entire Trench . 30 Conclusions.30 Comparison of Previous Paleoearthquake Chronologies.30 Physical Causes of Variable Earthquake Recurrence . 35 Implications of the Megatrench Results for Probability Estimates of Future Earthquakes on the Salt Lake City Segment . 36 References.38 Appendices.40 Appendix 1; Trench Unit Descriptions . 40
Towards inoculant development for Bambara groundnut (Vigna subterranean (L.) Verdc) pulse crop production in Namibia

Introduction The globally expanding population, together with climate change, poses a risk to the availability of food for humankind. Bambara groundnut (BGN) (Vigna subterranea (L.) Verdc) is a neglected, relatively drought-tolerant native legume of Sub-Saharan Africa that has the potential to become a successful food crop because of its nutritional quality and climate-smart features. Nitrogen fixation from root nodule symbiosis with climate-adapted rhizobial symbionts can contribute nitrogen and organic material in nutrient-poor soil and improve yields. However, high soil temperature and drought often reduce the abundance of native rhizobia in such soil. Therefore, the formulation of climate-smart biofertilizers has the potential to improve the farming of BGN at a low cost in a sustainable manner. Method The effect of seven Bradyrhizobium spp. strains native to Namibia, including B. vignae and B. subterraneum, were tested on three Namibian BGN varieties (red, brown, cream) in greenhouse pot experiments in Namibia, using soil from the target region of Kavango. Each variety was treated with a mixed inoculant consisting of seven preselected strains (“MK”) as well as with one promising single inoculant strain. Results The results revealed that in all three varieties, the two inoculants (mixed or single) outperformed the non-inoculated cultivars in terms of shoot dry weight by up to 70%; the mixed inoculant treatment performed significantly better (p < 0.05) in all cases compared to the single inoculant used. To test whether the inoculant strains were established in root nodules, they were identified by sequence analysis. In many cases, the indigenous strains of Kavango soil outcompeted the inoculant strains of the mix for nodule occupancy, depending on the BGN variety. As a further preselection, each of the individual strains of the mix was used to inoculate the three varieties under sterile conditions in a phytotron. The agronomic trait and root nodulation response of the host plant inoculations strongly differed with the BGN variety. Even competitiveness in nodule occupancy without involving any indigenous strains from soil differed and depended strictly on the variety. Discussion Severe differences in symbiont-plant interactions appear to occur in BGN depending on the plant variety, demanding for coupling of breeding efforts with selecting efficient inoculant strains.
Hybrid Force/Position Control of Multi-Mobile Manipulators for Cooperative Operation Without Force Measurements

In this paper, considering the difficulty of the interaction between the multi-mobile manipulators and the environment, the dynamics model of the mobile manipulator is analyzed, and a hybrid force/position control method based on the prescribed performance is proposed to improve the stability of the multi-mobile manipulators in the process of cooperative object transportation. Firstly, the dynamics model of the underdriven system of the multi-mobile manipulators is established by the Newton-Euler theorem. Then, the equivalent control theory is adopted for underdriven system, and a prescribed performance control method is proposed by considering the motion interference between the mobile manipulator and the high precision control of the manipulator. At the same time, an adaptive impedance control method is used to overcome internal and external disturbance during the cooperative transport of multi-mobile manipulators. The stability of the proposed method is analyzed through the Lyapunov stability theory. Finally, the effectiveness and superiority of the proposed scheme are verified through a simulation of multi-mobile manipulators collaborative object transportation.
A towed geophone system for use in snow-covered terrain

SUMMARY A new type of drag cable has been developed, which was successfully used to collect seismic reflection data on an Antarctic ice shelf. Standard geophone elements were encapsulated in polyurethane to form 25 m long, rectangular sections. Each of the 12 sections incorporated a group of 12 geophones. The resultant towed array resembles a 300m long flexible ski. The use of a towed cable provided substantial time and manpower savings over the use of planted geophones. In comparison with drag cables utilizing gimbal geophones, the towed array has a much lower coefficient of friction due to its smooth profile, and it is therefore possible to tow an array using snowmobiles. This provides a significant advantage because a system can be deployed by ski-equipped light aircraft to areas that are difficult or impossible to access using large vehicles. The simple construction of the towed array results in a lower cost than when gimbal cables are used. The main disadvantage is that the towed array has poorer wind-noise characteristics than gimbal cables or planted geophones. Use of the array enabled a team of four people to acquire 158 km of single-fold seismic reflection data on the Ronne Ice Shelf over two field seasons. The data are the first to show sub-seabed structure beneath this major ice shelf.
A case of unhealing skin ulcer with iatrogenic Cushing’s syndrome

Cutaneous Leishmaniasis is a rare disease in South-East Asian countries like Bangladesh, often presenting as skin lesions, ulcers or granulomatous plaques on the arm or back. As the disease is uncommon, high index of suspicion is required for the diagnosis. We are presenting a case of cutaneous Leishmaniasis in a migrant Bangladeshi worker in the Kingdom of Saudi Arabia (KSA). The case was initially treated with antibiotics, emollients and systemic steroid for a long time. However, the disease progressed, and the patient developed features of iatrogenic Cushing syndrome. The diagnosis was confirmed with a skin biopsy, which revealed Leishmania parasite. He received treatment with Injectable liposomal Amphotericin B (LAmB) and oral Miltefosine with promising clinical response. Clinicians should be vigilant while treating non-healing ulcers, and consider CL when there is history of travelling to CL endemic areas J Bangladesh Coll Phys Surg 2023; 41(4): 334-337
FastSRM: A fast, memory efficient and identifiable implementation of the shared response model

The shared response model (SRM) provides a simple but effective framework to analyze fMRI data of subjects exposed to naturalistic stimuli. However, when the number of subjects or runs is large, fitting the model requires a large amount of memory and computational power, which limits its use in practice. Furthermore, SRM is not identifiable, which makes the shared response difficult to interpret. In this work, we implement an identifiable version of SRM and show on real data that it improves the stability of the recovered shared response. We then introduce FastSRM, which relies on a dimension reduction step and yields the same solution as the original algorithm. We show experimentally using synthetic and real fMRI data that FastSRM is considerably faster and more memory efficient than current implementations. The experiments performed in this article are fully reproducible: our code available at https://github.com/hugorichard/FastSRM allows you to download the data, run the experiments and plot the figures. For a more pleasant reading of the math equations, we advise the reader to read the version of this article formatted with latex:https://github.com/hugorichard/FastSRM/blob/master/paper/main.pdf.
Sedimentary and petrographic analysis of the St. Peter sandstone

INTRODUCTION The St. Peter sandstone is the most widespread arenaceous terrane of the Ordovician in the Mississippi Valley region (Fig. 1). The formation has been studied and described in Illinois, Missouri, Arkansas, and Oklahoma, but has not been given a comprehensive sedimentary analysis in the upper Mississippi Valley. This study was undertaken in an attempt to determine the characteristics of the formation nearer the source of its sands and to compare the St. Peter of Minnesota and Wisconsin with that of the regions farther south (Fig. 1). It has been stated frequently that the St. Peter sandstone was derived from the Potsdam sandstone that cropped out around the south margin of the pre-Cambrian shield in the upper Mississippi Valley region during Ordovician time. These formations, already composed of well-sorted and well-rounded components, supplied the sands that characterize the St. Peter sandstone. These sands were delivered to the Ordovician sea by .
Dual-Polarized Antenna Arrays Based on Non-Uniform Partial Reflective Decoupling Layers for Vehicular Base Station Systems

In this paper, two non-uniform partially reflective decoupling layers (PRDLs) are applied to dual-polarized rectangular antenna arrays. By analyzing the coupled waves of the reference array and the reflected wave introduced by the PRDL, two-layer PRDLs are designed step-by-step. Compared to the array with only one-layer PRDL, the array with two-layer PRDLs can not only suppress various types of couplings but also improve the radiation performance. These PRDLs, which both have high dielectric constants in the two-dimensional plane, are composed of non-uniform artificial unit cells that are capable of reducing the cross-polarization discrimination (XPD) of the antennas while reducing the mutual coupling effectively. Simulated and measured results show that the isolation between antennas can be improved from 12 dB to more than 21 dB in the 1.71–2.2 GHz band, while the reflection coefficient remains below −15 dB. Compared with the reference array with no decoupling measures, the radiation pattern of the proposed array remains stable and the realized gain is increased. The proposed method is quite suitable for decoupling large-scale rectangular 5G MIMO arrays.
Effect of Hydrolysable Tannin on Nutrient Intake Obesity and Other Associated Metabolic Risk Factors in Polycystic Rats

Faiza Manzoor (  drfaizaahmadmmt@gmail.com ) Institute of Home and Food Science, Faculty of Life Sciences https://orcid.org/0000-0002-0905-5572 Mahr Un Nisa Institute of Home and Food Science, Faculty of Life Sciences Ha z Amjad Hussain Faisalabad Medical University, Faisalabad, Pakistan, Department of Internal Medicine Muhammad Kamran Khan Government College University, Faisalabad, Pakistan Rabia Shabir Ahmad Government College University, Faisalabad, Pakistan Nazir Ahmad Institute of Home and Food Science, Faculty of Life Sciences Muhammad Imran Institute of Home and Food Science, Faculty of Life Sciences Huma Umbreen Institute of Home and Food Science, Faculty of Life Sciences
Algorithm of Vehicle Speed Detection in Unmanned Aerial Vehicle Videos

The use of Unmanned Aerial Vehicles (UAVs) for traffic surveillance applications has been steadily growing by their unique advantages over the past few years. But at present the method which can extract traffic information from UAV videos still has many challenges, including camera motion, high object distance, varying object background or multiple objects near to each other. In this paper, an algorithm is proposed to track vehicle and extract its speed from the UAV videos. Firstly, detect feature points in the frames and match them, then choose the inner points from the matched points. Use the inner points to calibrate affine model and complete image registration by the model. Secondly, select the target by the way of human-computer interaction and use Camshift algorithm to track the target. Then a series of position coordinates about the moving target are extracted. Thirdly, use the affine model to calibrate the position coordinates obtained in the second step, then use the calibrated position coordinates and time interval to calculate the tracked target speed. Experiments have shown the results that the algorithm for different speed vehicles has good detection accuracy all above 92.4%.
Effect Verb Extraction on Crime Traditional Cluster

: Natural language processing (NLP) is a theory-motivated range of computational techniques for the automatic analysis and representation of human language. NLP used in text clustering for extraction the most important terms. The extraction research has evolved from period the Bag of Word to N-gram to part of sentence such as nouns and verbs, where the verbs terms play important role to differentiation each cluster about other. Still this method of extraction need to evaluate the effective on text clustering. This paper draws on use verbs extraction for text clustering using two datasets namely; real datasets about crime and industrial datasets using benchmark datasets. We identified the limitation of traditional clusters such as k-means on the initial centroids, for that's, we generated two new way of choose initial centroids to make the comparison more confident than the previous work.
Lawrence Berkeley Accelerator & Fusion Research

Increasing effort is being put into engineering designs of reactors and reactor-like magnetic confinement experiments. A central question concerns the methods of heating, fueling, and maintaining the plasmas, functions that primarily are now performed by neutral beams. Planning in the U.S.A. does not include' the use of neutral beams on tokamaks in the 1990's and beyond. Tandem mirrors, however, will use energetic beams ("sloshing ion" beams) in the end plugs to produce electrostatic potentials that will confine plasma ions. These systems will be based on the production, acceleration, transport, and neutralization of negative hydrogen-ion (0-), multiampere beams with energies of 200-to 500-keV. In addition, lower-energy D and T beams may be used. These systems must operate steady state, with high reliability, and be compatible with radiation from a D-T burning plasma. Planning for fusion reactors may change in the future, and tokamaks, tandem mirrors, and perhaps other confinement geometries eventually may use neutral beams for other functions, such as heating; in this case it may be desireable to inject polarized nuclei to adjust the reactivity and directionality of fusion products. In any event, all reactor experiments" may use high-energy neutral beams for diagnostics.
Modeling Rumor Spread and Influencer Impact on Social Networks

Social networks act as an indispensable component in the lives of individuals. However, misinformation and fake news are critical challenges in the digital world as people get persuaded towards false information. Though several fake news detection algorithms emerged, epidemic modeling is crucial in understanding the dissemination of fake news, which helps the policyholders to adopt control mechanisms to prevent the curb of infection within the networks. We propose a mathematical model of rumor spread by considering the human nature of selection and social influence within social networks by analyzing the stiffness of different global communities. The positivity of the model was mathematically proved, which proves the validity of the model within the real world. Our real-world data analysis showcases the possibility of a significant increase in fake news and misinformation within online digital networks during the COVID-19 pandemic. A comparative study using real-world data by extracting tweets shows that the proposed model outperforms the existing model. The significance of influencers in digital networks in disseminating rumors is discussed using the proposed model. The results can be used to analyze the impact of misinformation in different communities, which can help the policyholders implement necessary intervention mechanisms at the right time.
FACTORS THAT INCREASE DRYNESS PHENOMENON ON SMALL RIVERS IN PRUT BASIN (ANALYSIS OF CONDITIONALITIES)

This study aims to analyze factors causing increased of dryness phenomenon on small rivers in Prut basin. Are analyzed, the non-climate components of the landscape (relief, geology, soil, vegetation) and climatic factors on corresponding area (rainfalls). In reporting the number of years that has occurred dryness to number of years of observations showed that the frequency of the dryness phenomenon is over 90% for basins with areas less than 5 km 2 . The maximum period recorded without flow for small rivers in this basin was 292 days in 1987 on Ciurea hydrometric station closing Tinoasa catchment (A = 4.71 km 2 ) and 326 days on Humăria hydrometric station (A = 1.65 km 2 ) in the same basin. Should be noted the role of factors determine increasing phenomenon, namely geology (groundwater un-interception) and wooded areas (if smaller quantities of precipitation).
Biomass accumulation in trees and downed wood in northern hardwood forests: repeated measures of a successional chronosequence in New Hampshire, USA

Successional, second-growth forests dominate much of eastern North America, thus patterns of biomass accumulation in standing trees and downed wood are of great interest for forest management and carbon accounting. The timing and magnitude of biomass accumulation in later stages of forest development are not fully understood. We applied a “chronosequence with resampling” approach to characterize live and dead biomass accumulation in sixteen northern hardwood stands in the White Mountains of New Hampshire. Live aboveground biomass increased rapidly and leveled off at about 350 Mg/ha by 145 years. Downed wood biomass fluctuated between 10 and 35 Mg/ha depending on disturbances. The species composition of downed wood varied predictably with overstory succession, and total mass of downed wood increased with stand age and the concomitant production of larger material. Fine woody debris peaked at 30-50 years during the self-thinning of early-successional species, notably pin cherry. Our data support a model of northern hardwood forest development wherein live tree biomass accumulates asymptotically and begins to level off at ~140-150 years. Still, 145-year-old second-growth stands differed from old-growth forests in their live (p = 0.09) and downed tree diameter distributions (p = 0.06). These patterns of forest biomass accumulation would be difficult to detect without a time series of repeated measurements of stands of different ages.