Miracle-dz/UniFAR-FTUs huggingface dataset:
Asymmetric DRAM synthesis for heterogeneous chip multiprocessors in 3D-stacked architecture

Various computational requirements of real-world applications have leveraged moving to heterogeneous chip multiprocessors (CMPs) from homogeneous ones. In the meantime, three-dimensional integration of DRAMs and processors using Through Silicon Vias (TSVs) has emerged as the most viable solution for breaking the memory wall in CMP environment by bringing much higher memory bandwidth compared to current PCB level processor-DRAM integration. However, most researches on 3D-stacked DRAM have focused on increasing the memory bandwidth to improve the overall throughput of a system, even though the memory access requirements of real-world applications are various just as the computational requirements. To tackle this problem, we propose an asymmetric 3D-stacked DRAM architecture where the DRAM die is divided into multiple segments and the segments are optimized for different memory requirements. Also, since the optimal architecture of the DRAM can be different for different heterogeneous CMPs, we propose an automatic synthesis method for the asymmetric 3D-stacked DRAM architecture. The experimental results show that the area-power-product is reduced by 65.1% on average compared to the conventional architectures for the four realistic benchmarks and many of their derivatives.
Social Influences on the Creative Process: An Examination of Children's Creativity and Learning in Dance

The purpose of this paper is to look at the influences of social interaction and learning environment on children’s creativity in dance. Data from two separate studies are examined in which a total of thirty-seven fifth grade students created nine dances. This examination aims to (1) identify crucial elements of the classroom environment, which aided the students’ productivity and cognitive activity; and (2) look at how working as a peer group affected the participants’ creative process.
Intersectionality's Definitional Dilemmas

The term intersectionality references the critical insight that race, class, gender, sexuality, ethnicity, nation, ability, and age operate not as unitary, mutually exclusive entities, but rather as reciprocally constructing phenomena. Despite this general consensus, definitions of what counts as intersectionality are far from clear. In this article, I analyze intersectionality as a knowledge project whose raison d'etre lies in its attentiveness to power relations and social inequalities. I examine three interdependent sets of concerns: (a) intersectionality as a field of study that is situated within the power relations that it studies; (b) intersectionality as an analytical strategy that provides new angles of vision on social phenomena; and (c) intersectionality as critical praxis that informs social justice projects.
Affectionate Communication Received from Spouses Predicts Stress Hormone Levels in Healthy Adults

Recent research on the communication of affection illuminates its implications for mental and physical health. In particular, affectionate communication has been shown to covary with healthy hormonal variation and accelerated recovery from stress. The present study focuses on the association between marital affection and hormonal markers of stress regulation, including cortisol, dehydroepiandrosterone-sulfate (DHEA-S), and their ratio. Twenty healthy adults and spouses provided independent reports of their propensity for verbal, nonverbal, and support-based expressions of affection prior to providing saliva samples that were assayed for cortisol and DHEA-S. As hypothesized, spouses’ reports of verbal, nonverbal, and supportive affection significantly predicted participants’ waking cortisol levels, cortisol change, and cortisol:DHEA-S ratio. Participants’ own reports of affection were predictive of cortisol:DHEA-S ratio for verbal affection behaviors only, and were not predictive of participants’ waking cortisol, cortisol change, or DHEA-S. In addition, spouses’ reports of verbal, nonverbal, and supportive affection predicted participants’ evening cortisol levels. Results illustrate that affectionate communication from one's spouse is related to hormonal stress regulation and suggest the possibility that interventions designed to increase affectionate behavior in romantic relationships may have stress-ameliorating physiological effects.
Women's derogatory terms for men: That's right, “dirty” words

ABSTRACT Much of the research concerning “women's language” has focused on differences in pitch and intonation, expressions of uncertainty, and politeness and correctness of form; all predicated on the assumption that women are socially and linguistically conservative and therefore more likely to use standard or prestige forms. This is a study of the derogatory terms (“dirty” words) that women use to refer to men. The frequency and variance of response that results from the study calls into question the assumption that women are more prone to use standard forms of speech, and suggests that the standard/nonstandard distinction is more appropriately applied to the contrast between public versus private discourse than to that of the speech patterns of women versus the language use of men. (Women's language, linguistic taboos, response suppression, prestige forms, public and private discourse)
Correlation between antioxidant activity and coffee beverage quality by Electron Spin Resonance Spectroscopic

Brazil is the largest producer of coffee in the world and coffee prices are directly linked to grain quality. In this work, the antioxidant activity of coffee was related to its quality through Electron Spin Resonance Spectroscopy (ESR), as an attempt to establish a non-subjective method to classify the grain quality. For that purpose, the IC50 and temporal monitoring of its non-oxidized fraction were determined for three bean qualities: Soft (High), Hard (Medium) and Rio (Low). Methanolic solution of 2,2-difenil-1-picril-hidrazila (DPPH), that has a stable radical and a JEOL FA-200 (X-Band) spectrometer were used for these tests. The temporal monitoring of reaction between radical and coffee was performed. The rate of reduced or of antioxidated radicals was determined on time and for each coffee beverage quality were found different slopes of curve: Soft (0.32±0.02), Hard (0.47±0.02) and Rio (0.60±0.02). The IC50 result of Rio quality (2.7 ± 0.9) was different from the Soft (7.8 ± 1.9) and Hard (6.5 ± 1.5) values, but there was no difference between the High and Medium results due to the uncertainty associated. Therefore the results found, mainly for monitoring temporal, establish a new quantitative methodology for classifying the coffee beverage quality.
Widespread Transcriptional Autosomal Dosage Compensation in Drosophila Correlates with Gene Expression Level

Little is known about dosage compensation in autosomal genes. Transcription-level compensation of deletions and other loss-of-function mutations may be a mechanism of dominance of wild-type alleles, a ubiquitous phenomenon whose nature has been a subject of a long debate. We measured gene expression in two isogenic Drosophila lines heterozygous for long deletions and compared our results with previously published gene expression data in a line heterozygous for a long duplication. We find that a majority of genes are at least partially compensated at transcription, both for ½-fold dosage (in heterozygotes for deletions) and for 1.5-fold dosage (in heterozygotes for a duplication). The degree of compensation does not vary among functional classes of genes. Compensation for deletions is stronger for highly expressed genes. In contrast, the degree of compensation for duplications is stronger for weakly expressed genes. Thus, partial transcriptional compensation appears to be based on regulatory mechanisms that insure high transcription levels of some genes and low transcription levels of other genes, instead of precise maintenance of a particular homeostatic expression level. Given the ubiquity of transcriptional compensation, dominance of wild-type alleles may be at least partially caused by of the regulation at transcription level.
Consumer and Case Manager Agreement on Needs Assessments in Programs for Homeless Adults With Serious Mental Illness

Effective treatment planning is optimal when consumers’ perceived needs align with their providers’ assessments of those needs, which can facilitate collaborative partnerships and recovery-oriented services. This study compares consumers’ and case managers’ perceptions of consumer needs for adult clients in programs serving homeless adults with serious mental illness that use either a Housing First or non-Housing First (i.e., traditional) approach. Descriptive statistics were calculated based on a 20-item needs assessment checklist. The alternative chance-correlated coefficient (AC1) was used to assess level of overall agreement between individual consumer–case manager dyads while controlling for chance. Results of analyses with 72 consumer–case manager dyads show that although there was high agreement on the need for housing, case managers assessed greater needs in the clinical and social domains whereas consumers reported greater needs in the vocational and independent living domains, which did not differ between the Housing First and non-Housing First programs. Case managers and the consumers they serve show concordance in some areas of needs assessment; however, the areas of disagreement in perceived need may impede engagement and the delivery of recovery-oriented services, particularly when working with individuals experiencing multiple and sometimes competing needs such as homeless adults with serious mental illness.
The Venture Capital Revolution

Venture capital has emerged as an important intermediary in financial markets, providing capital to young high-technology firms that might have otherwise gone unfunded. Venture capitalists have developed a variety of mechanisms to overcome the problems that emerge at each stage of the investment process. At the same time, the venture capital process is also subject to various pathologies from time to time, which can create problems for investors or entrepreneurs. This article reviews the recent empirical literature on these organizations and points out area where further research is needed.
Intravenous transplantation of mesenchymal stem cells improves cardiac performance after acute myocardial ischemia in female rats

Mesenchymal stem cells (MSCs) are potential sources of cells for tissue repairing. However, little information is available regarding the therapeutic potency of intravenously transplanted MSCs for myocardial ischemia (MI). In the present study, MSCs were isolated from bone marrow of male rats and expanded in vitro. Three hours after ligation of left anterior descending artery, the transplanted group received an infusion of MSCs through the tail vein. At the same time, a coronary‐ligated control group was injected with culture medium. Homing of MSCs to the heart was assessed by expression of the Y chromosome sry gene using fluorescent in situ hybridization (FISH). At 1 week or 8 weeks after transplantation, sry positive cells were present in cardiac tissue in the transplanted group, but not in the hearts of control group. Cardiomyocytes, smooth muscle cells, and endothelial cells that bore sry gene were identified in transplanted group at 8 weeks after transplantation. Ultrastructural observation revealed that a large number of capillary and some immature myocytes were found to survive in the ischemia region. MSCs transplantation also decreased LVEDP pressure and −dP/dt, but increased LVSP and +dP/dt. The cardiac infarct size was significantly smaller in transplanted group than in control group. Our data suggest that intravenously transplanted MSCs improve cardiac performance and promote the regeneration of blood vessels and cardiomyocytes.
EGFR mutation and copy number, EGFR protein expression and KRAS mutation as predictors of outcome with erlotinib in bronchioloalveolar cell carcinoma (BAC): Results of a prospective phase II trial.

7003 Background: Erlotinib produces dramatic responses in a subset of patients with NSCLC. Mutations in the EGFR tyrosine kinase domain, EGFR amplification or polysomy and EGFR overexpression on immunohistochemistry have all been associated with sensitivity and benefit; pts with KRAS mutation are commonly resistant to this agent. These correlative studies were prospectively undertaken to characterize the ability of these markers to predict response rate, time to progression and survival in pts with BAC treated with the EGFR-TKI, erlotinib. METHODS One hundred and two patients received erlotinib as part of a phase II trial in BAC (Kris, Proc ASCO 2005); 84 had one or more correlative studies completed. Analysis of EGFR exons 19 and 21 (n=82) (Pao, et al PNAS 2004), EGFR IHC (n=62) (DAKO) was performed and EGFR copy number was determined by chromogenic in situ hybridization (CISH) (n=74) (Zymed); detection of ≥ 4 signals per cell was considered evidence of amplified copy number. KRAS exon 2 (n=79) testing was performed by direct sequencing. Fisher's exact test was used to study the association of each feature in pts with partial response or no partial response. Time to progression and survival were analyzed with log-rank test. RESULTS See table below. CONCLUSIONS 1) EGFR exon 19 or 21 mutation is a powerful predictor of response and TTP but not OS in pts with BAC treated with erlotinib. 2) CISH ≥4 is associated with response and improved TTP but not OS. 3) Patients with both EGFR mutation and amplification fare well supporting the concept of "oncogene addiction"; erlotinib should be considered as initial therapy in this population. 4) EGFR amplification without mutation is uncommon. 5) There is no clear utility of EGFR IHC in clinical decision making. 6) The presence of KRAS mutation predicts resistance to erlotinib. Supported, in part, by Genentech. [Table: see text] [Table: see text].
Emerging Pollutants – Part I: Occurrence, Fate and Transport

Part I: Occurrence, Fate, and Transport (this review) is a sequel of Emerging Pollutants. This review compiles research in 2014 for investigating emerging pollutants in wastewater and environmental sources of emerging pollutants. It investigates the occurrence, fate, transport of emerging pollutants in the environment. This review further discusses the monitoring approaches, modeling, and toxicological impacts of these compounds that are relevant to wastewater.
Loss, Gain, and Singular Points in Open Quantum Systems

Non-Hermitian quantum physics is used successfully for the description of different puzzling experimental results, which are observed in open quantum systems. Mostly, the influence of exceptional points on the dynamical properties of the system is studied. At these points, two complex eigenvalues Ei≡Ei+iΓi/2 of the non-Hermitian Hamiltonian H coalesce (where Ei is the energy and Γi is the inverse lifetime of the state i). We show that also the eigenfunctions Φi of the two states play an important role, sometimes even the dominant one. Besides exceptional points, other critical points exist in non-Hermitian quantum physics. At these points a=acr in the parameter space, the biorthogonal eigenfunctions of H become orthogonal. For illustration, we show characteristic numerical results.
Examining the Feasibility of Metasearch Based on Results of Human Judgements on Thai Queries

This paper provides the results of public Web search engine evaluation based on queries written in Thai. Statistical testing shows that there are some significant differences among engines. Besides comparing the effectiveness of Web search engines, the returned results are compared in order to illustrate the relation and overlap among these results. The results reveal that the majority of returned results are quite unique. Since the results among engines differ greatly, this encourages the use of metasearch approaches to combine best search results from different engines. We examine metasearch models based on the Borda count voting scheme. We also propose the use of evolutionary programming (EP) to optimize the weight vector used by the Borda count algorithm. The results show that the use of metasearch approaches produces superior performance compared to any single search engine on Thai queries.
Database Problem Behavior: A Literature Retrieval System for Professionals Dealing with Problem Behaviours of Individuals with Intellectual Disabilities

Knowledge of the literature among professionals in the area of problem behaviours and developmental disabilities is most likely soon out of date as several hundred useful studies appear each year. A literature database may be a useful tool for clinicians and researchers to conveniently retrieve needed information, preventing them from collecting, reading, processing, and storing all the available material. This report describes a database (i.e., Database Problem Behavior) encompassing information that goes far beyond presenting abstracts only. The third version of the database encompasses 885 empirical studies on the (functional) analysis, and behavioural and pharmacological treatment of problem behaviours (e.g., self‐injurious behaviour, aggressive behaviour, depression) for persons with developmental disabilities.
Housing Privatization and Housing Protest in the Transition from State Socialism: A Comparative Study of Budapest and Moscow

The focus of this paper is on housing privatization and housing conflict in moscow and Budapest since 1990. In Moscow the policy of 'free' housing privatization started in 1990 but take-up was low until 1992, after which there was a sharp rise to 35%. In Budapest housing privatization has involved payment and has risen slowly to 35 %. In Budapest the Tenants Association has had cooperative relations with the authorities, whereas in Moscow there has been sharp conflict between 'housing partnerships' and authorities. These patterns are explained in terms of tenants' motivations, institutional interests and the economic and political environment in the two cities. It is shown that these in turn reflect the different variants of state socialism in Hungary and Russia and the character of the 'transition' in each case. Particular emphasis is placed on the familiarity of the concept of home ownership, the level of personal economic security and the degree of institutional stability as immediate causes of the progress of housing privatization. The difference in patterns of housing conflict in the two cities is related to the degree of 'maturity' of democracy (with consequences for state responses to protest) and on the differentiation of commercial and residential property markets which affects the demands made in the housing privatization process.
Leadership Development as Identity Construction

The authors seek to broaden the focus and orientation of social constructionism in leadership development. Previous research has predominantly concerned identity-orientated approaches focused on regulation as opposed to construction of identity. Social constructionism challenges us to view leadership participants as subjects and objects. Using the concept of a “space of action,” the authors focus on places in leadership development where identity work is visible, inducing different kinds of agency. Three different responses are analyzed, exploring their implications for leadership development. The authors propose the importance of three communicative responses in allowing alternative identity storylines to remain open and active. The authors support leadership development as a site, discourse, and series of practices that equips us to work with identity in fluid, dynamic, and plural ways.
Determinants and mechanisms in ego identity development : A review and synthesis

Abstract The literature concerning the determinants and mechanisms of ego identity development is scattered and diverse. This article offers a review of this literature from different fields in the social sciences. Following a review, an attempt is made to integrate the ideas offered in the literature into an encompassing model of the process of identity development. The model describes identity development as an iterative process of person–context transactions. Conflicts arising in the course of these transactions are considered to trigger off development. The developmental trajectory is determined by the way in which these conflicts are solved. Optimal development requires a good balance between assimilation and accommodation of a person's commitments. Important determinants in this process are factors that enhance openness to change, environmental support, and the developmental history.
Glycosaminoglycans modulate inflammation and apoptosis in LPS‐treated chondrocytes

Previous studies reported that hyaluronic acid (HA), chondroitin sulphate (CS) and heparan sulphate (HS) were able to reduce the inflammatory process in a variety of cell types after lypopolysaccharide (LPS) stimulation. The aim of this study was to investigate the anti‐inflammatory effect of glycosaminoglycans (GAGs) in mouse articular chondrocytes stimulated with LPS. Chondrocyte treatment with LPS (50 µg/ml) generated high levels of TNF‐α, IL‐1β, IL‐6, IFN‐γ, MMP‐1, MMP‐13, iNOS gene expression and their related proteins, increased NO concentrations (evaluated in terms of nitrites formation), NF‐κB activation and IkBα degradation as well as apoptosis evaluated by the increase in caspase‐3 expression and the amount of its related protein. The treatment of chondrocytes using two different doses (0.5 and 1.0 mg/ml) of HA, chondroitin‐4‐sulphate (C4S), chondroitin‐6‐sulphate (C6S), HS, keratan sulphate (KS) and dermatan sulphate (DS) produced a number of effects. HA exerted a very small anti‐inflammatory and anti‐apoptotic effect while it significantly reduced NO levels, although the effect on iNOS expression and activity was extremely slight. C4S and C6S reduced inflammation mediators and the apoptotic process. C6S failed to decrease NO production, although iNOS expression and activity were significantly reduced. HS, like C4S, was able to reduce all the effects stimulated by LPS treatment. KS and DS produced no reduction in any of the parameters considered. These results give further support to the hypothesis that GAGs actively participate in the regulation of inflammatory and apoptotic processes. J. Cell. Biochem. 106: 83–92, 2009. © 2008 Wiley‐Liss, Inc.