Miracle-dz/UniFAR-FTUs huggingface dataset:
Communicating science in social contexts : new models, new practices

Part 1: Revisiting models. - 1. Paradigm change for science communication: commercial science needs a critical public. - 2. European trends in science communication. - 3. Words and figures of the public: the misunderstanding in scientific communication. - 4. Representation and deliberation: new perspectives on communication among actors in science and technology innovation. - 5. Medialisation of science as a prerequisite of its legitimisation and political relevance. - 6. On and about the deficit model in an age of free flow. - 7. Towards an analytical framework of science communication models. - Part 2: Crossing broundaries. - 8. Before and after science: science and technology in pop music, 1970 - 1990. - 9. The more, the earlier, the better: science communication supports science education. - 10. Hollywood knowledge: communication between scientific and entertainment cultures. - 11. Situating science in the social context by cross-sectoral collaboration. - Part 3: Developing strategies. - 12. From science communication to knowledge brokering: the shift from 'science push' to 'policy pull'. - 13. Science advocacy: challenging task, difficult pathways. - 14. The epistemic jumble of sustainable development. - 15. In search of dialogue: staging science communication in consensus conferences. - 16. So where's the theory? On the relationship between science communication practice and research. - 17. From democratization of knowledge to bridge building between science, technology and society. - 18. Bringing science to the public. - Appendix. - Index.
Scalable Load-Distance Balancing 1

We introduce the problem of load-distance balancing in assigning users of a delay-sensitive networked application to servers. We model the service delay experienced by a user as a sum of a network-incurred delay, which depends on its network distance from the server, and a server-incurred delay, stemming from the load on the server. The problem is to minimize the maximum service delay among all users. We address the challenge of finding a near-optimal assignment in a scalable distributed manner. The key to achieving scalability is using local solutions, whereby each server only communicates with a few close servers. Note, however, that the attainable locality of a solution depends on the workload – when some area in the network is congested, obtaining a near-optimal cost may require offloading users to remote servers, whereas when the network load is uniform, a purely local assignment may suffice. We present Ripple – an algorithm that exploits the opportunity to provide a local solution when possible, and thus has communication cost and stabilization time that vary according to the network congestion.
Amulet: An Energy-Efficient, Multi-Application Wearable Platform

Wearable technology enables a range of exciting new applications in health, commerce, and beyond. For many important applications, wearables must have battery life measured in weeks or months, not hours and days as in most current devices. Our vision of wearable platforms aims for long battery life but with the flexibility and security to support multiple applications. To achieve long battery life with a workload comprising apps from multiple developers, these platforms must have robust mechanisms for app isolation and developer tools for optimizing resource usage. We introduce the Amulet Platform for constrained wearable devices, which includes an ultra-low-power hardware architecture and a companion software framework, including a highly efficient event-driven programming model, low-power operating system, and developer tools for profiling ultra-low-power applications at compile time. We present the design and evaluation of our prototype Amulet hardware and software, and show how the framework enables developers to write energy-efficient applications. Our prototype has battery lifetime lasting weeks or even months, depending on the application, and our interactive resource-profiling tool predicts battery lifetime within 6-10% of the measured lifetime.
Molecular Characterization and Immune Protection of a New Conserved Hypothetical Protein of Eimeria tenella

The genome sequences of Eimeria tenella have been sequenced, but >70% of these genes are currently categorized as having an unknown function or annotated as conserved hypothetical proteins, and few of them have been studied. In the present study, a conserved hypothetical protein gene of E. tenella, designated EtCHP559, was cloned using rapid amplification of cDNA 5'-ends (5'RACE) based on the expressed sequence tag (EST). The 1746-bp full-length cDNA of EtCHP559 contained a 1224-bp open reading frame (ORF) that encoded a 407-amino acid polypeptide with the predicted molecular weight of 46.04 kDa. Real-time quantitative PCR analysis revealed that EtCHP559 was expressed at higher levels in sporozoites than in the other developmental stages (unsporulated oocysts, sporulated oocysts and second generation merozoites). The ORF was inserted into pCold-TF to produce recombinant EtCHP559. Using western blotting, the recombinant protein was successfully recognized by rabbit serum against E. tenella sporozoites. Immunolocalization by using EtCHP559 antibody showed that EtCHP559 was mainly distributed on the parasite surface in free sporozoites and became concentrated in the anterior region after sporozoites were incubated in complete medium. The EtCHP559 became uniformly dispersed in immature and mature schizonts. Inhibition of EtCHP559 function using anti-rEtCHP559 polyclonal antibody reduced the ability of E. tenella sporozoites to invade host cells by >70%. Animal challenge experiments demonstrated that the recombinant EtCHP559 significantly increased the average body weight gain, reduced the oocyst outputs, alleviated cecal lesions of the infected chickens, and resulted in anticoccidial index >160 against E. tenella. These results suggest that EtCHP559 plays an important role in sporozoite invasion and could be an effective candidate for the development of a new vaccine against E. tenella.
Cloning, Expression, and Characterization of a Thermostable PAP2L2, a New Member of the Type-2 Phosphatidic Acid Phosphatase Family from Geobacillus toebii T-85

Most members of the type-2 phosphatidic acid phosphatase (PAP2) superfamily are integral membrane phophatases involved in lipid-related signal transduction and metabolism. Here we describe the cloning of a novel gene from Geobacillus toebii T-85, encoding a PAP2-like protein, Gtb PAP2L2, which contains 212 amino acids and shows a limited homology to other known PAP2s, especially at conserved phosphatase motifs, and a similar six-transmembrane topology structure. This enzyme was expressed, and purified in Escherichia coli. Recombinant Gtb PAP2L2s from the membrane fractions were solublized with 0.3% (v/v) Triton X-100 and purified by Ni2+ affinity chromatography. The purified enzyme showed broad substrate specificity to phosphatidic acid, diacylglycerol pyrophosphate, and lysophosphatidic, but preferred phosphatidic acid and diacylglycerol pyrophosphate in vitro. Gtb PAP2L2 is a thermal stable enzyme with a half-life of 30 min at 60 °C. The enzyme was strongly inhibited by 1% SDS, 10 mM veranda, and Zn2+, whereas it was independent of the Mg2+ ion, and insensitive to N-ethylmaleimide. The purified recombinant Gtb PAP2L2 was catalytically active and highly stable, making it ideal as a candidate on which to base further PAP2 structure/function studies.
The Motile Breast Cancer Phenotype Roles of Proteoglycans/Glycosaminoglycans

The consecutive stages of cancer growth and dissemination are obligatorily perpetrated through specific interactions of the tumor cells with their microenvironment. Importantly, cell-associated and tumor microenvironment glycosaminoglycans (GAGs)/proteoglycan (PG) content and distribution are markedly altered during tumor pathogenesis and progression. GAGs and PGs perform multiple functions in specific stages of the metastatic cascade due to their defined structure and ability to interact with both ligands and receptors regulating cancer pathogenesis. Thus, GAGs/PGs may modulate downstream signaling of key cellular mediators including insulin growth factor receptor (IGFR), epidermal growth factor receptor (EGFR), estrogen receptors (ERs), or Wnt members. In the present review we will focus on breast cancer motility in correlation with their GAG/PG content and critically discuss mechanisms involved. Furthermore, new approaches involving GAGs/PGs as potential prognostic/diagnostic markers or as therapeutic agents for cancer-related pathologies are being proposed.
Chromaticity gamut enhancement by heptatone multicolor printing

The present paper studies the chromaticity gamut of multi-color printing processes. Heptatone (7-color) printing - the most promising variant of multi-color printing - offers a significantly larger gamut than a conventional CMYK printing process, approaching CRT and film gamuts. The behavior of the process in the device-independent CIE-XYZ and CIE-L*u*v* colorimetric spaces is explored using the compound Neugebauer model developed for this purpose. A simple and straightforward Moire-free separation process is proposed. The strong point of the proposed separation process is the fact that only 3 different screen layers are needed for any odd number of basic colors including black.
Urinary osteocalcin as a marker of bone metabolism.

BACKGROUND Osteocalcin (OC) is produced by osteoblasts during bone formation, and circulating OC has been used in clinical investigations as a marker of bone metabolism. OC is excreted into urine by glomerular filtration and can be found in urine as midmolecule fragments. METHODS We developed and evaluated three immunoassays (U-MidOC, U-LongOC, and U-TotalOC) for the detection of various molecular forms of urine OC (U-OC). We evaluated the association of U-OC with other markers of bone turnover and with bone mass in 1044 elderly women and studied seasonal and circadian variation of U-OC. RESULTS U-OC correlated with other bone turnover markers [Spearman correlation (r), 0.30-0.57; P <0.0001], demonstrating the association between U-OC and skeletal metabolism. There was also a significant association between bone metabolism assessed by U-OC quartiles and bone mass assessed by total body bone mineral content (P <0.0001). The seasonal effects appeared to be rather small, but we observed a significant circadian rhythm similar to the one reported for serum OC with high values in the morning and low values in the afternoon. CONCLUSIONS The three immunoassays had unique specificities toward different naturally occurring U-OC fragments. U-OC concentrations measured with any of these assays correlated with bone turnover rates assessed by conventional serum markers of bone metabolism. The measurement of OC in urine samples could be used as an index of bone turnover in monitoring bone metabolism.
FF12MC: A revised AMBER forcefield and new protein simulation protocol

Specialized to simulate proteins in molecular dynamics (MD) simulations with explicit solvation, FF12MC is a combination of a new protein simulation protocol employing uniformly reduced atomic masses by tenfold and a revised AMBER forcefield FF99 with (i) shortened CH bonds, (ii) removal of torsions involving a nonperipheral sp3 atom, and (iii) reduced 1-4 interaction scaling factors of torsions ϕ and ψ This article reports that in multiple, distinct, independent, unrestricted, unbiased, isobaric-isothermal, and classical MD simulations FF12MC can (i) simulate the experimentally observed flipping between left-and right-handed configurations for C14-C38 of BPTI in solution, (ii) autonomously fold chignolin, CLN025, and Trp-cage with folding times that agree with the experimental values, (iii) simulate subsequent unfolding and refolding of these miniproteins, and (iv) achieve a robust Z score of 1.33 for refining protein models TMR01, TMR04, and TMR07. By comparison, the latest general-purpose AMBER forcefield FF14SB locks the C14-C38 bond to the right-handed configuration in solution under the same protein simulation conditions. Statistical survival analysis shows that FF12MC folds chignolin and CLN025 in isobaric-isothermal MD simulations 2-4 times faster than FF14SB under the same protein simulation conditions. These results suggest that FF12MC may be used for protein simulations to study kinetics and thermodynamics of miniprotein folding as well as protein structure and dynamics.
Pelatihan Penulisan Artikel Ilmiah Guru Bahasa Inggris SMA di Kota Semarang (sebagai Pencapaian KEPMENPAN Nomor 16 Tahun 2009 Tentang Jabatan Fungsional Guru dan Angka Kreditnya)

This community service was held in a training of writing scientific article. The main goal of this community service is to help the teachers to write a scientific article which is proper to published in an accredited scientific journal. It was held in a long term and took eleven meetings. It started in June 19,2012 and ended in June 27, 2012. There were six English teachers participated as samples of this community service. They were well-trained to write a scientific article. Finally, they are able to write a scientific article and it is published on ETERNAL Journal. Key words: scientific article, KEPMENPAN No 16 tahun 2009, Jabatan fungsional guru dan angka kredit. e? a Kegiatan Pengabdian kepada masyarakat ini dilaksanakan dalam bentuk pelatihan penulisan artikel ilmiah. Kegiatan ini bertujuan untuk membantu para guru untuk mampu menghasilkan sebuah artikel yang layak untuk dipublikasikan dalam sebuah jurnal ilmiah yang terakreditasi. Kegiatan pengabdian kepada masyaralat ini dilaksanakan dalam jangka waktu yang relative panjang yaitu mencapai 11 petemuan yang belangsung dari tanggal 19 Juni 2012 sampai 27 Juli 2012. Ada enam guru bahasa inggris yang menjadi sample dalam pengabdian kepada masyarakat ini. Keenam guru tersebut kemudian didampingi dan diarahkan dalam menulis sebuah artikel ilmiah sesuai dengan ketentuan untuk dapat dipublikasikan dalam sebuah jurnal ilmiah. Berdaarkan hasil kegiatan, ke enam guru yang didampingi berhasil membuat satu artikel ilmiah yang sudah layak untuk publikasi. Kata kunci: artikel ilmiah, KEPMENPAN No 16 tahun 2009, Jabatan fungsional guru dan angka kredit.
Full duplex relay in millimeter wave backhaul links

With the increase interest in developing small cells architecture for wireless communication, providing backhaul to the basestations is a major challenge. This paper propose the use of Amplify-and-Forward (AF) full duplex (FD) relays in millimeter wave (mmWave) communication in wireless backhaul links between the cells. We are using hybrid (analog and digital) beamforming to overcome the propagation losses of outdoor mmWave environment. The proposed system performance was analyzed using channels with limited number of paths. Results show significant performance improvement for the full duplex links over half duplex links. The results also show how the antenna array size at the source and destination influences the system performance.
Developmental Analysis in Evolutionary Robotics

This paper presents a developmental analysis of robot controllers created using evolutionary robotics (ER) methods. ER uses artificial evolution to automatically design and synthesize intelligent robot controllers. An aggregate fitness function that injects relatively little a priori task knowledge into the evolving controllers was used. We analyze the course of development of robot controllers evolving to perform a competitive goal-locating task. To sample the course of evolution, controllers were taken from progressively more advanced generations, and were then tested in a novel environment. Developments and changes in the controllers' abilities and competencies were identified and correlated with overall controller fitness. As evolution progressed, it was found that robots evolved more complex high-level behaviors that were not explicitly selected for by the fitness function.
Performance Analysis of Cognitive Radio Networks against Secondary User's Policies

In a cognitive radio network (CRN), instead of direct leaving, an interrupted secondary user (SU) is suspended to wait for another channel. The policy for the packets generated by the SU during the suspending time can be either discarding or buffering. This paper mainly analyzes the performance of a CRN against these two policies. Here, two Markov models are proposed to derive the formulas for packet loss ratio, packet delay and spectrum utilization. Numerical results show that theoretical models are consistent with simulation results. The major observations include (i) The performance of a CRN is more sensitive to the primary users’ traffic loads than that of secondary users and (ii) adopting discarding or buffering policy for the packets of SUs does not make much difference to the CRN’s spectrum utilization.
Sucrose Accumulation and Harvest Schedule Recommendations for CP Sugarcane Cultivars

Sugarcane (Saccharum spp.) is harvested during a 5-month period (October to March) in the Everglades Agricultural Area (EAA) of south Florida. The genetic and temporal variability of sugarcane sucrose concentration is well established, but sucrose accumulation curves have not been reported for the Canal Point (CP) clones used in Florida since 1977. The objective of this study was to compare sucrose accumulation for recently released clones and provide harvest schedule recommendations based on this information. Thirteen CP clones were sampled at 2-week intervals throughout 4 consecutive harvest seasons. Based on seasonal changes in cultivar ranking in sugar per ton, recommended harvest scheduling relative to October 14 (time = 0 days) are: early-season (0 to 50 days) for cultivars CP 70-1133, CP 80-1743, and CP 88-1762; mid-season (50 to 100 days) for cultivars CP 78-1628 and CP 84-1198; and late-season (100 to 150 days) for cultivars CP 72-1210, CP 72-2086, CP 80-1827, CP 85-1382, CP 88-1508, and CP 89-2377. Sucrose accumulation in cultivar CP 89-2143 was greatest across all harvest periods and should be grown by Florida producers interested in improving the sucrose concentration of their crop.
Vasa Vasorum and Plaque Neovascularization on Contrast-Enhanced Carotid Ultrasound Imaging Correlates With Cardiovascular Disease and Past Cardiovascular Events

Background and Purpose— Histological data associate proliferation of adventitial vasa vasorum and intraplaque neovascularization with vulnerable plaques represented by symptomatic vascular disease. In this observational study, the presence of carotid intraplaque neovascularization and adventitial vasa vasorum were correlated with the presence and occurrence of cardiovascular disease (CVD) and events (CVE). Methods— The contrast-enhanced carotid ultrasound examinations of 147 subjects (mean age 64±11 years, 61% male) were analyzed for the presence of intraluminal plaque, plaque neovascularization (Grade 1=absent; Grade 2=present), and degree of adventitial vasa vasorum (Grade 1=absent, Grade 2=present). These observations were correlated with preexisting cardiovascular risk factors, presence of CVD, and history of CVE (myocardial infarction and transient ischemic attack/stroke). Results— The presence of intraluminal carotid plaque was directly correlated to cardiovascular risk factors, CVD, and CVE (P<0.05). Adventitial vasa vasorum Grade 2 was associated with significant more subjects with CVD than vasa vasorum Grade 1 (73 versus 54%, P=0.029). Subjects with intraplaque neovascularization Grade 2 had significantly more often a history of CVE than subjects with intraplaque neovascularization Grade 1 (38 versus 20%, P=0.031). Multivariate logistic regression analysis revealed that presence of plaque was significantly associated with CVD (odds ratio 4.7, 95% CI 1.6 to 13.8) and intraplaque neovascularization grade 2 with CVE (odds ratio 4.0, 95% CI 1.3 to 12.6). Conclusion— The presence and degree of adventitial vasa vasorum and plaque neovascularization were directly associated with CVD and CVE in a retrospective study of 147 patients undergoing contrast-enhanced carotid ultrasound.
Converging methods for understanding reading and dyslexia

Offers an interdisciplinary look at the acquisition, loss and remediation of normal reading processes. The book aims to illustrate various approaches used by scientists to understand the complex skill of reading and its breakdown, and to stimulate innovative research strategies. It is divided into five sections: normal adult reading and its development; developmental dyslexia; varieties of brain-damaged reading; neuroimaging; and computational modelling.
Molecular Systems Biology Peer Review Process File Dynamics of Protein Noise Can Distinguish between Alternate Sources of Gene-expression Variability Transaction Report

(Note: With the exception of the correction of typographical or spelling errors that could be a source of ambiguity, letters and reports are not edited. The original formatting of letters and referee reports may not be reflected in this compilation.) Thank you again for submitting your work to Molecular Systems Biology. We have now heard back from two of the three referees who agreed to evaluate your manuscript, and have decided to render a decision now to avoid further delay. As you will see from the reports below, the referees generally found the method proposed in this work potentially interesting. Both independently indicated, though, that additional experimental work would be needed to rigorously validate the ability of this method to distinguish transcription and translational noise, before it would be appropriate for publication in Molecular Systems Biology. Each reviewer makes specific recommendations for additional experiments that could potentially help address their concerns. If you feel you can satisfactorily deal with the points listed by the referees, you may wish to submit a revised version of your manuscript. Please attach a covering letter giving details of the way in which you have handled each of the points raised by the referees. A revised manuscript will be once again subject to review and you probably understand that we can give you no guarantee at this stage that the eventual outcome will be favorable. When preparing your revised work, the raw intensity data for Fig. 3, requested by Reviewer #1, can be provided as "figure source data". Please see our Instructions of Authors for more details on preparation and formatting of figure source data
Combinatorial Interpretations of the Jacobi-Stirling Numbers

The Jacobi-Stirling numbers of the first and second kinds were introduced in the spectral theory and are polynomial refinements of the Legendre-Stirling numbers. Andrews and Littlejohn have recently given a combinatorial interpretation for the second kind of the latter numbers. Noticing that these numbers are very similar to the classical central factorial numbers, we give combinatorial interpretations for the Jacobi-Stirling numbers of both kinds, which provide a unified treatment of the combinatorial theories for the two previous sequences and also for the Stirling numbers of both kinds.