Miracle-dz/UniFAR-FTUs huggingface dataset:
Visualization of shared system call sequence relationships in large malware corpora

We present a novel system for automatically discovering and interactively visualizing shared system call sequence relationships within large malware datasets. Our system's pipeline begins with the application of a novel heuristic algorithm for extracting variable length, semantically meaningful system call sequences from malware system call behavior logs. Then, based on the occurrence of these semantic sequences, we construct a Boolean vector representation of the malware sample corpus. Finally we compute Jaccard indices pairwise over sample vectors to obtain a sample similarity matrix. Our graphical user interface links two visualizations within an interactive display. Our first view is a map-like visualization of similarity among the samples based on a reduced dimensional projection of our similarity matrix. Our second view provides insight into similarities and differences between selected malware samples in terms of the system call sequences they share. We also provide a set of interactive filters based on malicious behavioral traits. The integration of these views into an interactive, linked display allows users to comprehend the overall similarity structure of a malware corpus, inspect how behavioral traits distribute over the corpus, and to drill in to inspect local similarities and differences between samples.
Oxidized‐LDL and Atherosclerosis: Role of LOX‐1

Abstract: The accumulation of substantial numbers of monocyte/macrophages and activated T lymphocytes in focal areas of the arterial intima appears to be a hallmark of atherosclerosis. Our report demonstrated that lysophosphatidylcholine (lyso‐PC), a polar phospholipid component that is increased in atherosclerotic lipoproteins, such as oxidized LDL and remnant lipoproteins in diabetic and Type 3 hyperlipidemia, can upregulate adhesion molecules for monocytes and T lymphocytes, and growth factors, such as heparin‐binding epidermal growth factor‐like growth factor and PDGF A and B chains. Recently, we identified the novel receptor for oxidized LDL, named LOX‐1. We summarize the importance of the interaction between oxidized LDL and its receptor, LOX‐1, in terms of early stage atherogenesis.
A New Notion of Weighted Centers for Semidefinite Programming

The notion of weighted centers is essential in V-space interior-point algorithms for linear programming. Although there were some successes in generalizing this notion to semidefinite programming via weighted center equations, we still do not have a generalization that preserves two important properties---(1) each choice of weights uniquely determines a pair of primal-dual weighted centers, and (2) the set of all primal-dual weighted centers completely fills up the relative interior of the primal-dual feasible region. This paper presents a new notion of weighted centers for semidefinite programming that possesses both uniqueness and completeness. Furthermore, it is shown that under strict complementarity, these weighted centers converge to weighted centers of optimal faces. Finally, this convergence result is applied to homogeneous cone programming, where the central paths defined by a certain class of optimal barriers for homogeneous cones are shown to converge to analytic centers of optimal faces in the presence of strictly complementary solutions.
Towards a Computational Model of Dramatic Tension

One of the approaches to generate narrative consists in modeling narrative in terms of a deep structure, as introduced by narrative theories in the middle of the 20th century. This papers revisits this computational approach, and raises the central issue of dramatic tension: Would it be possible to build a computational model of dramatic tension, where tension could be managed according to the well known ascending/descending dramatic curve? The paper describes a new computational model of narrative, based on a set of structural narrative elements (goals, tasks, obstacles, side-effects), a hierarchical and modular approach, a paradox-based model of dramatic tension and a solution for managing endings. The papers illustrates this theoretical model with a full example.
Stochastic relations of random variables and processes

This paper generalizes the notion of stochastic order to a relation between probability measures over arbitrary measurable spaces. This generalization is motivated by the observation that for the stochastic ordering of two stationary Markov processes, it suffices that the generators of the processes preserve some, not necessarily reflexive or transitive, subrelation of the order relation. The main contributions of the paper are: a functional characterization of stochastic relations, necessary and sufficient conditions for the preservation of stochastic relations, and an algorithm for finding subrelations preserved by probability kernels. The theory is illustrated with applications to hidden Markov processes, population processes, and queueing systems.
Reducing Binge Drinking? The Effect of a Ban on Late-Night Off-Premise Alcohol Sales on Alcohol-Related Hospital Stays in Germany

Excessive alcohol consumption among youth and young adults is a major public health concern. On March 1, 2010 the German federal state of Baden-W rttemberg banned the sale of alcoholic beverages between 10pm and 5am in off-premise outlets (e.g. kiosks, petrol stations, supermarkets). We use rich monthly administrative data from a 70 percent random sample of all hospitalizations for the years 2007-2010 in Germany in order to evaluate the impact of this policy on alcohol-related hospitalizations. Applying a difference-in-difference approach, we find that the policy change reduces alcohol-related hospitalizations among adolescents and young adults by about 9 percent. The empirical results suggest that limiting late hours during which alcoholic beverages are allowed to be sold is an effective and rather "costless" public health initiative for reducing high-risk drinking among youth and young adults.
De la CSR-Corporate Social Responsability à la RSO-Responsabilité Sociale des Organisations. Quelques apports à la réflexion

Le concept traditionnel de la RSE n’inclut pas dans son cadre l’Economie Sociale et l’Administration Publique. Etre socialement responsable signifie avoir une âme et agir en tant que citoyen responsable. Pour inclure l’Economie Sociale et l’Administration Publique dans le concept et le cadre de la RSE, nous avons besoin d’une autre approche et d’un concept different. L’OSR integre une dimension de la RSE traditionnelle, brise les barrieres des compagnies, et generalise l’attitude « socialement responsable » a la societe. Dans cet article, l’auteur revele un nouveau concept, des dimensions nouvelles et de nouveaux modeles, permettant a tout type d’organisme de trouver sa propre maniere de progresser et ses reperes.
Dichioroacetate Increases Skeletal Muscle Pyruvate Dehydrogenase Activity During Acute Limb lschemia

The purpose of this study was to evaluate the effects of dichloroacetate sodium (DCA), a drug that inactivates pyruvate dehydrogenase kinase (PDH-K), on pyruvate dehydrogenase (PDH) activity, lactate level, and function of skeletal muscle in an experimental model of acute limb ischemia. Thirty-two male Sprague-Dawley rats underwent right iliac artery ligation to produce hindlimb ischemia. After 2 hours of ischemia, 16 animals received intravenous DCA (15 mg/i 00 g body weight) and 16 control animals received an equivalent volume of normal saline. After an additional 1 hour of ischemia (total 3 hours) tibialis anterior muscle from the ischemic limb and contralateral nonischemic limb was excised, rapidly freeze-clamped with Wallenberg tongs cooled in liquid nitrogen, and stored at -700C. Muscles specimens were subsequently assayed for PDH activity and lactate level by use of spectrophotometric techniques. An additional 16 animals (DCA-treated, n = 8; control, n = 8) underwent ex-vivo gastrocnemius muscle fatigue testing with a 10 g tension preload after 3 hours of limb ischemia. In ischemic hind limbs, DCA treatment significantly (p = 0.025) increased PDH activity (19.6 ±1.6 pmol/min/g dry weight) compared to controls (13.1 ± 1.3 pmol/min/g dry weight). DCA treatment did not increase (p = 0.13) skeletal muscle PDH activity in the nonischemic limbs (9.6 ± 1.1 umol/min/g dry weight, controls; 13.2 ±1.3 pmol/min/g dry weight, DCA group). In DCA-treated animals, hind limb ischemia resulted in no significant increase in muscle lactate levels compared to the nonischemic limb, while control animals demonstrated a significant (p = 0.005) elevation in lactate level in ischemic limbs compared to contralateral nonischemic limb. Ischemia induced a significant decrease in time to muscle fatigue in both DCA-treated and control animals (p=0.002 and 0.001, respectively). Time to muscle fatigue in DCA-treated animals was increased compared to controls (2.6 ±0.3 versus 2 ±0.6 minutes; p< 0.05) in ischemic limbs but was not significantly different in nonischemic limbs (DCA = 3.3 ±0.5 minutes; control = 3.1 ±0.6 minutes). Treatment with DCA during acute limb ischemia reduced the depression of PDH activity and lactate level of skeletal muscle. Ischemic muscle function was also improved by DCA treatment. Further investigation of the potential beneficial effects of DCA treatment on muscle injury during ischemia and reperfusion is warranted.
Arresting moments in engaged management research

We contribute to the literature on the production of knowledge through engaged management and organisational research. We explore how relational practices in management and organisational research may interpenetrate and change one another, thereby potentially producing new knowledge. We demonstrate the importance of the disruptive qualities of arresting moments in this process. We present data from within ongoing engaged management and organisational research at an arts festival involving related music, management and research practices, during which two arresting moments arose: one in our own core research practice, the other in related music and management practices. We found arresting moments were preceded by increasingly intense divisions between practices, when practitioners experienced increasingly entrenched views and heightened emotions. Arresting moments sometimes followed, producing an empathetic connection between practitioners, so that they could suddenly see situations from a new perspective. In this way, arresting moments could produce opportunities for (self-) reflexivity and the possibility of reconstructing knowing in relational practices.
The Effect of Religiosity on Alienation: A Multivariate Analysis of Normlessness

Abstract Religiosity constitutes a neglected variable in the research of alienation. The present study tests a theory of the effect of religiosity on the alienation dimension of normlessness. Data from the 1973 and 1976 NORC General Social Surveys suggest that the higher the religiosity, the lower the normlessness. This relationship is independent of variables drawn from other theories of normlessness such as the perspectives which link social class and urbanism to anomie. The notion that religious integration should foster integration into the larger normative social system is modestly supported by two indicators of religiosity: belief in religion and attendance of religious services. Evidence is also found for a sex role theory of normlessness, wherein females report more anomie than males. However, education and level of occupational prestige prove to be the conditions most closely tied to normlessness, both in the negative direction.
TLR4 signaling induces the release of microparticles by tumor cells that regulate inflammatory cytokine IL-6 of macrophages via microRNA let-7b

Tumor cells expressing TLRs is generally recognized to mediate tumor inflammation. However, whether and how tumor TLR signaling pathways negatively regulate tumor inflammation remains unclear. In this report, we find that TLR4 signaling of H22 hepatocarcinoma tumor cells is transduced through MyD88 pathway to actin cytoskeletons, leading to the release of microparticles (MPs), the cellular membrane-derived vesicles. As a result, tumor macrophages take up MPs and acquire MP-contained microRNA let-7b, which attenuates tumor inflammation by targeting proinflammatory cytokine IL-6. Thus, tumor TLR signaling, contrary to the original promoting effect, may play an opposite role in downregulating tumor inflammation through MP pathways.
Intraaneurysmal pressure reduction with carotid occlusion. Observations in three cases of middle cerebral aneurysms.

O CCLUSION of the cervical carotid artery has been used in the treatment of intracranial aneurysms for several decades. It has seemed that aneurysms arising from the internal carotid artery have been most successfully managed by this procedure although it has at times been used for aneurysms at other sites. Sweet and Bennett S in 1948 were the first to record pressure alterations within the cervical carotid artery in patients undergoing proximal occlusion of the vessel. No direct measurements of pressure within intracranial aneurysms have been reported. Gallagher, 4 Mullan, et al., ~,6 and Alksne, et al., 1 have shown recently that fine hairs, wires, and needles can be safely inserted into aneurysms in an attempt to produce thrombosis by newly developed techniques. We are reporting pressure measurements in three cases of middle cerebral aneurysms treated by direct attack on the lesion. This group was chosen because of the relative ease of exposure of such aneurysms and because their peripheral location would make them more accessible should complicating hemorrhage ensue.
Exceptions to Mutual Trust: Children's Use of Second-Order Beliefs in Responsibility Attribution

Children of 6 to 9 years and adults judged a story protagonist's degree of blame for a traffic accident. All stories depicted a collision between a protagonist, who had the right of way, and another road user. Stories differed, however, in protagonist's second-order belief about the other road-user's knowledge. For instance, in one story, the protagonist mistakenly thought that the other had noticed her coming and that she could therefore rely on him abiding by the priority rule (principle of mutual trust) and grant her the right of way. This story contrasted with one where the protagonist knew that the other had not seen her and so was not justified in claiming priority. Most 7 and 8-year-old children understood the difference in second-order belief and about half of them were also able to make the correct responsibility attribution that the mistaken protagonist, thinking the other character knew, was less to blame for the accident than the one who knew about the other's ignorance. By 9 years, almost all children understood second-order beliefs and three-quarters were also able to make the correct responsibility attribution. The application of second-order beliefs to the principle of mutual trust is discussed in relation to communication failures and cooperative interaction.
Uplink performance analysis of GAS-CP CDMA system

In this paper, we propose a GAS-CP-CDMA(cyclic-prefix code division multiple access system that uses Sequences with good autocorrelation property) and analyze the uplink signal-to-noise ratio performance of that system. Phase-shifted sequences are used for differentiating users. The signals of the GAS-CP-CDMA system experience no (or very little) interferences from co-cell signals because of the good autocorrelation property, but user signals of adjacent cells may yield interferences. The frequency reuse factor in the ordinary CDMA system is around 0.6 and the interference from adjacent cells is about 40 percent of the total interference in the conventional CDMA system. Our numerical analysis shows that the frequency reuse factor and user capacity versus signal-to-noise ratio of the GAS-CP-CDMA system are improved comparing to the conventional CDMA system. The uplink user capacity of the proposed system can be increased up to about twice of that of the conventional CDMA system.
Retrospective Review of Relapse after Systemic Cyclosporine in Children with Atopic Dermatitis

Cyclosporine is a systemic therapy used for control of severe atopic dermatitis (AD) in children. Although traditionally recommended at a dose of 5 mg/kg/day for 6 months, a longer duration of treatment may be necessary to bring a child with active and severe disease into remission. There are few data on the short‐ and long‐term effectiveness of longer courses of therapy. This was a retrospective chart review of children treated with cyclosporine at a Canadian hospital‐affiliated clinic between 2000 and 2013. Fifteen patients with adequate follow‐up were identified. Twelve (80%) were male and the mean age at initiation of cyclosporine was 11.2 ± 3.4 years. The mean duration of cyclosporine therapy was 10.9 ± 2.7 months (range 7–15 months) at a starting dose of 2.8 ± 0.6 mg/kg/day. Of 12 patients (80%) who responded to cyclosporine, 5 patients (42%) had relapsed at a follow‐up of 22.7 ± 15.0 months. The duration of therapy was longer in patients who did not relapse (17.7 ± 10.7 months) than in those who did (10.2 ± 2.7 months) (p = 0.06). Adverse events led to discontinuation in three patients (20%) and included infection‐related complications in two patients and reversible renal toxicity in one. These results suggest that a longer duration of low‐dose cyclosporine may help decrease the risk of relapse in patients with severe AD who are resistant to topical therapies.
Themes in Judges' Sentencing Remarks for Male and Female Domestic Murderers

The aim of this study was to analyse judges' sentencing remarks in cases of domestic murder. In undertaking a qualitative analysis, the methodology of grounded theory was used, and the data emanating from the judges' sentencing remarks identified several major themes as discussed in this article. Broadly speaking, the data reflect that women are viewed more harshly than men and receive higher sentences. In addition, judges are distancing male offenders from their responsibility for their violent conduct, rendering them potential candidates for more lenient treatment in terms of sentence. The analysis also reveals that judges frequently rely on stereotypes and traditional notions of marriage, family and femininity in determining an offender's sentence. These assumptions are embedded in the different set of descriptors used by judges to describe male and female offenders.
Clindamycin 1% Nano-emulsion Gel Formulation for the Treatment of Acne Vulgaris: Results of a Randomized, Active Controlled, Multicentre, Phase IV Clinical Trial.

BACKGROUND Acne vulgaris of the face is a common dermatological disease with a significant impact on the quality of life, psychosocial development as well as self-esteem of the patients. Nano emulsion gel formulations are said to have various advantages over the conventional formulations. AIM The present study was conducted to assess the comparative efficacy and safety of a nano-emulsion gel formulation of clindamycin with its conventional formulation in the treatment of acne vulgaris of the face. MATERIALS AND METHODS This prospective, active controlled, multicentric, phase IV clinical trial evaluated the treatment of patients with acne vulgaris of the face by a nano emulsion gel formulation or conventional gel formulation of clindamycin (as phosphate) 1% locally applied twice daily for 12 weeks as per random allocation. Acne lesion counts (inflammatory, non-inflammatory and total) and severity grading were carried out on the monthly scheduled visits along with tolerability assessments. RESULTS A total of 200 patients (97 males) were included for Intention to Treat analysis in the trial with 100 patients in each group. Reductions in total (69.3 vs. 51.9%; p<0.001), inflammatory (73.4 vs. 60.6%; p<0.005) and non inflammatory (65.1 vs. 43.7%; p<0.001) acne lesions were reported to be significantly greater with the nano-emulsion gel formulation as compared to the conventional gel formulation. Significantly more reduction in the mean acne severity score was noticeable with the nano-emulsion gel formulation (-1.6 ± 0.9 vs. -1.0 ± 0.8; p<0.001) than the comparator. A trend towards better safety profile of the nano emulsion gel formulation was reported. CONCLUSION In the treatment of acne vulgaris of the face, clindamycin nano emulsion gel formulation appears to be more effective than the conventional gel formulation and is also well tolerated.
Practical OFDMA in wireless networks with multiple transmitter-receiver pairs

State-of-the-art physical layers such as OFDMA are widely used in infrastructure-based networks to enhance efficiency in one-to-many transmissions. Application to wireless mesh networks is highly promising, as the diversity increases in many-to-many scenarios. While theoretical work on OFDMA for this scenario exists, it has not yet been implemented in practice. In this demonstration, we show practical measurements of OFDMA in a topology with multiple transmitters and receivers, which represents a fully-connected segment of a mesh network. Moreover, we model our system analytically and in simulation. Our measurements show the validity of these models. We demonstrate over 90% reduction of the symbol error rate and a 29% channel capacity increase.
Automatic Beam Path Analysis of Laser Wakefield Particle Acceleration Data

Numerical simulations of laser wakefield particle accelerators play a key role in the understanding of the complex acceleration process and in the design of expensive experimental facilities. As the size and complexity of simulation output grows, an increasingly acute challenge is the practical need for computational techniques that aid in scientific knowledge discovery. To that end, we present a set of data-understanding algorithms that work in concert in a pipeline fashion to automatically locate and analyze high energy particle bunches undergoing acceleration in very large simulation datasets. These techniques work cooperatively by first identifying features of interest in individual timesteps, then integrating features across timesteps, and based on the information derived perform analysis of temporally dynamic features. This combination of techniques supports accurate detection of particle beams enabling a deeper level of scientific understanding of physical phenomena than has been possible before. By combining efficient data analysis algorithms and state-of-the-art data management we enable high-performance analysis of extremely large particle datasets in 3D. We demonstrate the usefulness of our methods for a variety of 2D and 3D datasets and discuss the performance of our analysis pipeline.