Miracle-dz/UniFAR-FTUs huggingface dataset:
Psychological characteristics of mothers of patients with anorexia nervosa: implications for treatment and prognosis.

INTRODUCTION The complexity of factors involved in anorexia nervosa (AN) and the recommendations of prominent health organizations underscore the importance of reflecting on therapeutic interventions aimed at patients' family members. OBJECTIVE To expand knowledge about the mother-daughter relationship in AN, with a focus on developing a conceptual framework that is able to improve the treatment of the disorder, reduce factors that perpetuate it and improve prognosis. METHOD A clinical method, anchored by psychodynamic references, was employed in a group of family members of patients with eating disorders. The group met weekly, and sessions were led by psychologists from the eating disorder outpatient clinic of a university hospital. RESULTS AND DISCUSSION Common characteristics in the mother-daughter relationship in cases of AN were identified. The issue of mutual control, the dialectic between omnipotence and impotence, and the relationship of devotion, passion and annihilation between mothers and daughters are phenomena that form the basis of AN, with a direct influence on the severity of each case and on treatment success. CONCLUSION Our findings allowed us to identify important aspects in the mother-daughter relationship in AN, which may improve the clinical interventions aimed at treating the disorder.
Toward autonomous avian-inspired grasping for micro aerial vehicles

Micro aerial vehicles, particularly quadrotors, have been used in a wide range of applications. However, the literature on aerial manipulation and grasping is limited and the work is based on quasi-static models. In this paper, we draw inspiration from agile, fast-moving birds such as raptors, that are able to capture moving prey on the ground or in water, and develop similar capabilities for quadrotors. We address dynamic grasping, an approach to prehensile grasping in which the dynamics of the robot and its gripper are significant and must be explicitly modeled and controlled for successful execution. Dynamic grasping is relevant for fast pick-and-place operations, transportation and delivery of objects, and placing or retrieving sensors. We show how this capability can be realized (a) using a motion capture system and (b) without external sensors relying only on onboard sensors. In both cases we describe the dynamic model, and trajectory planning and control algorithms. In particular, we present a methodology for flying and grasping a cylindrical object using feedback from a monocular camera and an inertial measurement unit onboard the aerial robot. This is accomplished by mapping the dynamics of the quadrotor to a level virtual image plane, which in turn enables dynamically-feasible trajectory planning for image features in the image space, and a vision-based controller with guaranteed convergence properties. We also present experimental results obtained with a quadrotor equipped with an articulated gripper to illustrate both approaches.
Laboratory and exterior decay of wood–plastic composite boards: voids analysis and computed tomography

ABSTRACT After exposure in the field and laboratory soil block culture testing, the void content of wood–plastic composite (WPC) decking boards was compared to unexposed samples. A void volume analysis was conducted based on calculations of sample density and from micro-computed tomography (microCT) data. It was found that reference WPC contains voids of different sizes from the micrometer range up to several cubic millimeters. Large voids were unevenly distributed within the composite sample. Void size and volume increased after conditioning the WPC in water at 70°C. Depending on the effect of exposure conditions, fungal decay during laboratory soil block testing increased the size and volume of voids. For laboratory samples, the calculated void volume was much higher compared to microCT-detected voids because of the limited resolution of the instrument on relatively large samples with many nano- and microvoids present in the material. In both laboratory and field samples, the creation of the voids resulted in a significant decrease in composite density. Decay damage observed as an increase in the size and volume of voids was particularly severe for boards exposed in the field. The calculated void volume in such samples was in reasonable agreement with voids detected by microCT.
Specification and Design of a Fault Recovery Model for the Reliable Multicast Protocol

The Reliable Multicast Protocol (RMP) provides a unique, group-based model for distributed programs that need to handle reconfiguration events at the application layer. This model, called membership views, provides an abstraction in which events such as site failures, network partitions, and normal join-leave events are viewed as group reformations. RMP provides access to this model through an application programming interface (API) that notifies an application when a group is reformed as the result of a some event. RMP provides applications with reliable delivery of messages using an underlying IP Multicast media to other group members in a distributed environment even in the case of reformations. A distributed application can use various Quality of Service (QoS) levels provided by RMP to tolerate group reformations. This paper explores the implementation details of the mechanisms in RMP that provide distributed applications with membership view information and fault recovery capabilities.
Incidence and mortality of ischemic stroke subtypes in Joinville, Brazil: a population-based study.

AIMS To measure the incidence and mortality rates of ischemic stroke (IS) subtypes in Joinville, Brazil. METHODS All first-ever IS patients that occurred in Joinville from January 2005 to December 2006 were identified. The IS subtypes were classified by the TOAST criteria, and the patients were followed-up for one year after IS onset. RESULTS The age-adjusted incidence per 100,000 inhabitants was 26 (17-39) for large-artery atherosclerosis (LAA), 17 (11-27) for cardioembolic (CE), 29 (20-41) for small vessel occlusion (SVO), 2 (0.6-7) for stroke of other determined etiology (OTH) and 30 (20-43) for stroke of undetermined etiology (UND). The 1-year mortality rate per 100,000 inhabitants was 5 (2-11) for LAA, 6 (3-13) for CE, 1 (0.1-6) for SVO, 0.2 (0-0.9) for OTH and 9 (4-17) for UND. CONCLUSION In the population of Joinville, the incidences of IS subtypes were similar to those found in other populations. These findings highlight the importance of better detection and control of atherosclerotic risk factors.
People Power - Computer Games in the Classroom

This article presents a case study in the use of the computer simulation game People Power , developed by the International Center on Nonviolent Conflict. The principal objective of the activity was to offer students an opportunity to understand the dynamics of social conflicts, in a format not possible in a traditional classroom setting. Due to the game complexity, it was decided to play it in a day-long (8 hour) workshop format. A computer lab was prepared several weeks beforehand, which meant that each team of four students had access to a number of computers, being able to have the game open on several monitors at the same time, playing on one while using the others to constantly revise information as their strategy and tactics evolved. At the end of the workshop, and after handing in a group report, the 24 participants (6 groups) were asked to complete a short survey of the activity. The survey was divided into three areas: the game itself, skill development, and the workshop organization. Results showed a strong relationship between the activity and the course content, skills and competencies development, and practical know-how and leadership, as well as a strong feeling that it works well as a learning tool and is enjoyable. DOI: 10.18870/hlrc.v4i1. 200
Benefits of physical activities centered on the trunk for pregnant women

ABSTRACT Objective: To examine the effect of a trunk exercise program on pain, quality of life (QoL) and physical health (PH) in the late pregnancy and post-partum periods as well as baby weight and size and delivery. Methods: 90 nulliparous women were allocated based on voluntarism to a training group (TG) or to a control group (CG). TG carried out a structured program with exercises for flexibility, balance and strengthening for the majority of skeletal muscles specifically for the spinal ones, between the 24th and 36th week of pregnancy. Both TG and CG were evaluated for pain at the beginning of the program (T1), at the end of the program (T2) and two months’ post-partum (T3). QoL was assessed at T1,T2 and T3, and PH at T1 and T3. Mann-Whitney test was utilized to compare TG and CG on each period and to compare the periods two by two. Results: At T1, no significant difference was found between the two groups in pain intensity (pain interference p = 0.317), QoL (p = 0.18) and PH (flexibility p = 0.06; walking p = 0.85). At T2, women of TG had a lower intensity of pain than CG (legs (p = 0.029), lower back (p < 0.0001), upper back (p = 0.022), pelvis (p = 0.017), groins (p = 0.043), lower pelvis (p = 0.009) and interference of pain (p < 0.0001)). At T3, TG had a lower intensity of pain than CG, in lower back and upper back (p < 0.0001) and interference of pain (p < 0.0001). Best scores of QoL were observed in TG compared to CG at T2 (p < 0.0001) and at T3 (p < 0.0001). PH in TG compared to CG was not different between the groups in T1 but was different in in T3 (flexibility p = 0.002, walking, balance, curling-ups and Ruffier p < 0.0001). TG were four times less likely to have a caesarean (p = 0.049) and had 4.5 h less of labor time (p < 0.0001). No difference was observed between the TG vs CG concerning the weight (p = 0.22) and the baby’s size (p = 0.11). Conclusion: Strengthening exercises centered on the trunk reduce pain, improve QoL and PH in late pregnancy and at two months in the post-partum period. Strengthening exercises also ease the delivery.
Spontaneous Improvement of Compensatory Knee Flexion After Surgical Correction of Mismatch Between Pelvic Incidence and Lumbar Lordosis

Study Design. A retrospective study. Objective. The aim of this study was to investigate the correlation between pelvic incidence (PI) and lumbar lordosis (LL) mismatch and knee flexion during standing in patients with lumbar degenerative diseases and to examine the effects of surgical correction of the PI-LL mismatch on knee flexion. Summary of Background Data. Only several studies focused on knee flexion as a compensatory mechanism of the PI-LL mismatch. Little information is currently available on the effects of lumbar correction on knee flexion in patients with the PI-LL mismatch. Methods. A group of patients with lumbar degenerative diseases were divided into PI-LL match group (PI-LL ⩽ 10°) and PI-LL mismatch group (PI-LL > 10°). A series of radiographic parameters and knee flexion angle (KFA) were compared between the two groups. The PI-LL mismatch group was further subdivided into operative and nonoperative group. The changes in KFA with PI-LL were examined. Results. The PI-LL mismatch group exhibited significantly greater sagittal vertical axis (SVA), pelvic tilt (PT) and KFA, and smaller LL, thoracic kyphosis (TK), and sacral slope than the PI-LL match group. PI-LL, LL, PI, SVA, and PT were significantly correlated with KFA in the PI-LL mismatch group. From baseline to 6-month follow-up, all variables were significantly different in the operative group with the exception of PI, although there was no significant difference in any variable in the nonoperative group. The magnitude of surgical correction in the PI-LL mismatch was significantly correlated with the degree of spontaneous changes in KFA, PT, and TK. Conclusion. The PI-LL mismatch would contribute to compensatory knee flexion during standing in patients with lumbar degenerative disease. Surgical correction of the PI-LL mismatch could lead to a spontaneous improvement of compensatory knee flexion. The degree of improvement in knee flexion depends in part on the amount of correction in the PI-LL mismatch. Level of Evidence: 3
Utilization of Primary Care Among College Students With Mental Health Disorders

Objective: Our goal was to assess whether integration of behavioral and medical services in college settings is associated with decreased use of primary care by patients with mental health diagnoses (MHDs). Method: The cohort consisted of 80,219 patients with at least 1 MHD in 21 universities. Two levels of service integration were defined: “standard”—universities with separate electronic health records (EHR) systems and minimal clinical collaboration between services, and “enhanced”—universities with shared EHR and collaborative patient care. Frequency, the total number of primary care visits, and complexity, the total visit length for primary care per unit time, were compared by using multilevel models. Results: Nine schools met the criteria of enhanced clinical integration; a tenth school shifted to enhanced service during the study period. Student and patient demographics and clinical diagnoses were similar between the 2 categories. When controlling for variance in age, sex, and total time in school, patients with MHDs in standard systems had 15.72% (95% confidence interval [CI]: 10.77%–20.44%) more primary care visits and 22.88% (95% CI: 21.42%–24.38%) more time than patients in enhanced systems. Conclusions: Students with MHDs have significantly lower utilization of primary care services in integrated health care systems, but only a minority of institutions nationally have adopted this model of care. Although further research is needed to specifically assess differences in health outcomes and perceived suffering, it is possible that reduced primary care visits in enhanced integrative service settings with robust mental health support indicates overall reduction in perceived suffering for patients/clients.
Understanding energy consumption of UHF RFID readers for mobile phone sensing applications

We argue that augmenting a mobile phone with an UHF RFID reader has the potential to expand the scope of mobile phone sensing applications. We investigate an important issue that arises when contemplating such integration --- the energy consumption characteristics of state of the art compact UHF RFID readers collecting data from nearby sensor tags. Our experimental study shows that a typical operation using a compact UHF RFID reader consumes much less energy compared to sensors commonly present in mobile phones such as GPS, thereby supporting the case for UHF RFID reader integration with mobile phones.
Choroidal and Retinal Thickness of Highly Myopic Eyes with Early Stage of Myopic Chorioretinopathy: Tessellation

Purpose To investigate the choroidal thickness (CT) and retinal thickness (RT) in highly myopic tessellated eyes. Methods In this study, 115 highly myopic eyes were recruited and divided as tessellated fundus (n = 93) and normal fundus (n = 22). RT and CT were quantified using optical coherence tomography with enhanced depth imaging (EDI-OCT). Correlation between subfoveal CT (SFCT) and tessellation was analyzed using logistic regression models. Results Tessellated fundus eyes had thinner CT than did normal fundus eyes, while RT was not statistically different across groups. The tessellated eyes had a thinner choroid than did the control eyes at all measured macular locations (all P < 0.05). After adjustment for AL, age, and gender, the SFCT was significantly associated with tessellation. The odds ratio (OR) and 95% confidence interval (CI) was 0.975 (0.960–0.990, P = 0.001, binary logistics regression) and 0.991 (0.984–0.999, P = 0.022, Cox regression). The area under the curve (AUC) of SFCT was the greatest for detecting tessellation (AUC = 0.824, P < 0.001). For sensitivity and specificity analyses, SFCT had the highest diagnostic value (sensitivity = 81.8%, specificity = 74.2%). Conclusions Highly myopic eyes with tessellation have thinner CT than do normal highly myopic eyes. CT may serve as an early pathologic predictor of high myopia.
In situ polymerized hyperbranched polymer reinforced poly(acrylic acid) hydrogels

Hydrogels have been extensively investigated for use in various applications. Poly acrylic acid (PAA) is a common example, which has been widely used due to its super hydrophilicity properties, biocompatibility and biodegradability characteristics. However its poor mechanical properties, which have been addressed in many research studies, are known as a drawback that limits its applications. So, enhancing PAA mechanical properties using a hyperbranched polymer (HB) is the key question to be addressed in this research. Investigations of the mechanical properties of the PAA-HB hydrogel revealed 130% improvement in the ultimate tensile strength, indicating a two times enhancement compared to that of PAA. Statistical analysis showed that the overall effect of introducing notches (with different depths) on the selected mechanical properties of both PAA and PAA-HB was significant. Mechanical characterization of PAA-HB networks showed that significant improvement in the mechanical properties was achieved as the capability of water uptake increased by 20%. Characterization of the physical properties confirmed that participation of HB may form a PAA based hybrid material with good swelling properties. Those findings are attributed to the supramolecular structure of the HB, which can introduce physical entanglement between the PAA network structure and increase the crystallinity of the final hydrogel as compared to those from the PAA hydrogel.
Deep sequencing of natural and experimental populations of Drosophila melanogaster reveals biases in the spectrum of new mutations

Mutations provide the raw material of evolution, and thus our ability to study evolution depends fundamentally on whether we have precise measurements of mutational rates and patterns. Here we explore the rates and patterns of mutations using i) de novo mutations from Drosophila melanogaster mutation accumulation lines and ii) polymorphisms segregating at extremely low frequencies. The first, mutation accumulation (MA) lines, are the product of maintaining flies in tiny populations for many generations, therefore rendering natural selection ineffective and allowing new mutations to accrue in the genome. In addition to generating a novel dataset of sequenced MA lines, we perform a meta-analysis of all published MA studies in D. melanogaster, which allows more precise estimates of mutational patterns across the genome. In the second half of this work, we identify polymorphisms segregating at extremely low frequencies using several publicly available population genomic data sets from natural populations of D. melanogaster. Extremely rare polymorphisms are difficult to detect with high confidence due to the problem of distinguishing them from sequencing error, however a dataset of true rare polymorphisms would allow the quantification of mutational patterns. This is due to the fact that rare polymorphisms, much like de novo mutations, are on average younger and also relatively unaffected by the filter of natural selection. We identify a high quality set of ~70,000 rare polymorphisms, fully validated with resequencing, and use this dataset to measure mutational patterns in the genome. This includes identifying a high rate of multi-nucleotide mutation events at both short (~5bp) and long (~1kb) genomic distances, showing that mutation drives GC content lower in already GC-poor regions, and finding that the context-dependency of the mutation spectrum predicts long-term evolutionary patterns at four-fold synonymous sites. We also show that de novo mutations from independent mutation accumulation experiments display similar patterns of single nucleotide mutation, and match well the patterns of mutation found in natural populations.
Mevalonate kinase deficiency: current perspectives

Mevalonate kinase deficiency (MKD) is a recessively inherited autoinflammatory disorder with a spectrum of manifestations, including the well-defined clinical phenotypes of hyperimmunoglobulinemia D and periodic fever syndrome and mevalonic aciduria. Patients with MKD have recurrent attacks of hyperinflammation associated with fever, abdominal pain, arthralgias, and mucocutaneous lesions, and more severely affected patients also have dysmorphisms and central nervous system anomalies. MKD is caused by mutations in the gene encoding mevalonate kinase, with the degree of residual enzyme activity largely determining disease severity. Mevalonate kinase is essential for the biosynthesis of nonsterol isoprenoids, which mediate protein prenylation. Although the precise pathogenesis of MKD remains unclear, increasing evidence suggests that deficiency in protein prenylation leads to innate immune activation and systemic hyperinflammation. Given the emerging understanding of MKD as an autoinflammatory disorder, recent treatment approaches have largely focused on cytokine-directed biologic therapy. Herein, we review the current genetic and pathologic understanding of MKD, its various clinical phenotypes, and the evolving treatment approach for this multifaceted disorder.
Type-Safe Programming with OWL in Semantics4J

Programming with OWL is error-prone due to the lack of type-safe integration into programming languages. While generic types such as Resource can represent anything the data can model, they make it impossible to errorcheck programs. Mapping ontological concepts into types of the programming language on the other hand often cannot capture the ontology completely and duplicates knowledge that a semantic reasoner already has. Semantics4J, an extended Java compiler, allows for type-safe programming with OWL by integrating DL expressions as types and values into the programming language. This paper presents a prototype that supports our theoretical concept [4] by relying on an extended type-checking process building upon a reasoner as well as class expression queries that are being used as types themselves.
A numerical study of Mach 6 boundary layer stabilization by means of a porous surface

Direct numerical simulations are carried out of boundary layer flow at Mach 6 over a porous surface, in which a Mack mode of instability is excited. The pores are resolved rather than modelled, allowing an evaluation to be made of the accuracy of simplified one-dimensional models used in previous investigations based on linear stability theory. The simulations confirm the stabilizing effect of porosity. The effect is stronger in the simulations than in the corresponding theory. From comparisons of spanwise grooves, streamwise slots and square pores it appears that the detailed surface structure is not as important as the overall porosity and the hydraulic diameter is able to collapse the results for different pore shapes to good accuracy. When the porous surface consists of fewer larger pores, the flow is noisier, with sound waves generated at the pore edges.