Miracle-dz/UniFAR-FTUs huggingface dataset:
Training Application for Industries by Means of Virtual Reality Technology: A Recent Study

One of the pylons of the Industry 4.0 is augmented and virtual reality. It can improve the perception on the industrial processes in real time and more. The purpose of these research is to obtain a starting point regarding the actual abilities to enlarge the use of VR HMDs (e.g.: HTC Vive, Oculus Rift, etc.), assembling into a unique application, Virtual and Augmented Reality with Gesture Interaction. The project relies on the Leap Motion controller. This controller have an integrated infrared depth camera wich can be used as an input video feed for stereoscopic view on Oculus Rift, in the same time, projecting the raw images of your hands into a 3D mesh that can interact with other objects in real-world space (in our case a 3D model of a complex product). The pass through from the twin Leap Motion cameras covers the part of the mesh such that each camera assures a distinct view of the hands, letting you see the actual depth. We can interact with the 3D model and show some functional animations. We present a part of a industrial application of VR used into a common industry (door locks manufacturing industry), which can be useful for research and for training and advertising too.
Suppressive control of the crustacean pyloric network by a pair of identified interneurons. II. Modulation of neuronal properties

In the lobster Homarus, the 2 identified PS neurons have a strong suppressive modulatory effect on the activity of the pyloric network in the STG (Cazalets et al., 1990). In the present paper, we consider the effects of PS on individual pyloric neurons isolated from their partners in the network by cell photoinactivation and synaptic blockade. Three types of PS action are described: (1) a transient, EPSP- mediated depolarization of the PD, VD, and AB neurons; (2) a long- lasting hyperpolarization concomitant with a loss of oscillatory properties in the PD and LP neurons; (3) a long-lasting depolarization without modification of oscillatory properties in the PY and IC neurons. The various effects of PS on isolated pyloric cells were consistent with the overall effects of PS on the intact pyloric network.
Building Data-Driven Pathways From Routinely Collected Hospital Data: A Case Study on Prostate Cancer

Background Routinely collected data in hospitals is complex, typically heterogeneous, and scattered across multiple Hospital Information Systems (HIS). This big data, created as a byproduct of health care activities, has the potential to provide a better understanding of diseases, unearth hidden patterns, and improve services and cost. The extent and uses of such data rely on its quality, which is not consistently checked, nor fully understood. Nevertheless, using routine data for the construction of data-driven clinical pathways, describing processes and trends, is a key topic receiving increasing attention in the literature. Traditional algorithms do not cope well with unstructured processes or data, and do not produce clinically meaningful visualizations. Supporting systems that provide additional information, context, and quality assurance inspection are needed. Objective The objective of the study is to explore how routine hospital data can be used to develop data-driven pathways that describe the journeys that patients take through care, and their potential uses in biomedical research; it proposes a framework for the construction, quality assessment, and visualization of patient pathways for clinical studies and decision support using a case study on prostate cancer. Methods Data pertaining to prostate cancer patients were extracted from a large UK hospital from eight different HIS, validated, and complemented with information from the local cancer registry. Data-driven pathways were built for each of the 1904 patients and an expert knowledge base, containing rules on the prostate cancer biomarker, was used to assess the completeness and utility of the pathways for a specific clinical study. Software components were built to provide meaningful visualizations for the constructed pathways. Results The proposed framework and pathway formalism enable the summarization, visualization, and querying of complex patient-centric clinical information, as well as the computation of quality indicators and dimensions. A novel graphical representation of the pathways allows the synthesis of such information. Conclusions Clinical pathways built from routinely collected hospital data can unearth information about patients and diseases that may otherwise be unavailable or overlooked in hospitals. Data-driven clinical pathways allow for heterogeneous data (ie, semistructured and unstructured data) to be collated over a unified data model and for data quality dimensions to be assessed. This work has enabled further research on prostate cancer and its biomarkers, and on the development and application of methods to mine, compare, analyze, and visualize pathways constructed from routine data. This is an important development for the reuse of big data in hospitals.
Tessellations of Moduli Spaces and the Mosaic Operad

We construct a new (cyclic) operad of `mosaics' defined by polygons with marked diagonals. Its underlying (aspherical) spaces are the sets of real points of the moduli space of punctured Riemann spheres, which are naturally tiled by Stasheff associahedra. We (combinatorially) describe them as iterated blow-ups and show that their fundamental groups form an operad with similarities to the operad of braid groups.
Effect on Health-Related Outcomes of Interventions to Alter the Interaction Between Patients and Practitioners: A Systematic Review of Trials

PURPOSE We wanted to identify published randomized trials of interventions to alter the interaction between patients and practitioners, develop taxonomies of the interventions and outcomes, and assess the evidence that such interventions improve patients’ health and well-being. METHODS Undertaking a systematic review of randomized trials, we sought trials in primary and secondary care with health-related outcomes, which we found by searching MEDLINE, HealthSTAR, and PsycINFO bibliographic databases through 1999. We also completed one round of manual citation searching. RESULTS Thirty-five trials were included. Most were set in primary care in North America. Trials were heterogeneous in populations, settings, interventions, and measures. Interventions frequently combined several poorly described elements. Explicit theoretical underpinning was rare, and only one study linked intervention through process to outcome measures. Health outcomes were rarely measured objectively (6 of 35), and only 4 trials with health outcomes met predefined quality criteria. Interventions frequently altered the process of interactions (significantly in 73%, 22 of 30 trials). Principal outcomes favored the intervention group in 74% of trials (26 of 35), reaching statistical significance in 14 (40%). Positive effects on health outcomes achieved statistical significance in 44% of trials (11 of 25); negative effects were uncommon (5 of 25, 20%). Simple approaches to increasing the participation of patients in the clinical encounter, such as providing practitioners with a note from patients about their concerns beforehand, showed promise, as did more complex programs providing specific information about disease and attention to emotion. Apparently similar interventions varied in effectiveness across studies. CONCLUSIONS Successful interactions between patients and their practitioners lie at the heart of medicine, yet there are few rigorous trials of well-specified interventions to inform best practice. Trial evidence suggests that a range of approaches can achieve changes in this interaction, and some show promise in improving patients’ health. To advance knowledge further, we need to replicate promising studies using rigorous methods. These should include explicit theoretical frameworks designed to link effects on key communication and interaction characteristics through to effects on health outcomes.
Low-density lipoprotein receptor overexpression enhances the rate of brain-to-blood Aβ clearance in a mouse model of β-amyloidosis

The apolipoprotein E (APOE)-ε4 allele is the strongest genetic risk factor for late-onset, sporadic Alzheimer's disease, likely increasing risk by altering amyloid-β (Aβ) accumulation. We recently demonstrated that the low-density lipoprotein receptor (LDLR) is a major apoE receptor in the brain that strongly regulates amyloid plaque deposition. In the current study, we sought to understand the mechanism by which LDLR regulates Aβ accumulation by altering Aβ clearance from brain interstitial fluid. We hypothesized that increasing LDLR levels enhances blood–brain barrier-mediated Aβ clearance, thus leading to reduced Aβ accumulation. Using the brain Aβ efflux index method, we found that blood–brain barrier-mediated clearance of exogenously administered Aβ is enhanced with LDLR overexpression. We next developed a method to directly assess the elimination of centrally derived, endogenous Aβ into the plasma of mice using an anti-Aβ antibody that prevents degradation of plasma Aβ, allowing its rate of appearance from the brain to be measured. Using this plasma Aβ accumulation technique, we found that LDLR overexpression enhances brain-to-blood Aβ transport. Together, our results suggest a unique mechanism by which LDLR regulates brain-to-blood Aβ clearance, which may serve as a useful therapeutic avenue in targeting Aβ clearance from the brain.
High-Speed Dual-Gate a-IGZO TFT-Based Circuits With Top-Gate Offset Structure

Owing to bulk-accumulation, dual-gate (DG) amorphous-indium-gallium-zinc-oxide (a-IGZO) thin-film transistors (TFTs) with top- and bottom-gates electrically tied together (DG-driving) exhibit 2.53 times higher ON-current and subthreshold voltage swing of ~ 180 mV/decade, which is 50% lower than that of single-gate (SG)-driven a-IGZO TFTs. Here, through simulation and experimental results, we demonstrate that the use of DG-driven back-channel-etched a-IGZO TFTs with a top-gate offset structure enhances the switching speed of a-IGZO TFT-based circuits. In particular, fabricated SG-driven and DG-driven 11-stage ring oscillators exhibited respective oscillating frequencies of 334 and 781 kHz.
GPS VIRTUAL STATION TECHNIQUE ( GPSSIT ) AND ITS CHALLENGE IN TERRESTRIAL PHOTOGRAMMETRIC APPLICATIONS

GPS Virtual Station technique fundamentally depends on determination of a virtual point by GPS that is just about 1,5 meters above the ground or a platform surface and then to the use of it by other surveying and/or photogrammetric instruments such as a total station and/or a camera. Thus, the technique offers a challenge in terrestrial photogrammetry to determine the coordinates of control points distributed on each facade of any object in any size and in a reference system, which is globally available, and without using a network of points set up on the ground and surrounding the object. The technique is also capable of determination of camera perspective centre’s coordinates by the use of GPS Virtual Station which is determined by the GPS antenna. In this process, first, GPS antenna is set up on a tripod with a leveled triprach to collect GPS Virtual Station coordinates and then it is removed from the triprach and replaced with a camera (i.e. digital camera) in a similar way of that can even be followed with total station to be used for the measurement of control points on the facades. So, it means that the network of points to be set up for the measurements of control points on the objects in interest and which is the most cost effective part of a over all project is removed, no more hustle for it, and three unknown parameters are now known values when considering that the camera perspective centre is determined as GPS Virtual Station, and so that the number of control points on the facades can be reduced, and there is no location limitation for chose of points, so that they can freely be chosen at any time (even in the middle of a measurement section if some kinds of problems are met, such as GPS signal blockage and object coverage problems) at any where around the object and finally, every object measured using this technique in any part of the world can easily and spatially linked and referred to one another with respect to the same reference system. In this study, the technique mentioned above was utilised to create a final product as an originally textured virtual reality 3D photogrametric model of a historical site, which is a unique sample of a cultural asset remained from its own time. It is Aladdin Mosque built up at the top of the Aladdin Hill where takes place at the centre of Konya. 3D model of the site is also ready to be put into the internet and onto a CD to distribute and interact in a GIS environment. As a final outcome of this study, it can be stated that the technique proposed here represents an encouraging performance in the point of accuracy, and project speed and economy as well.
Evolutionary Dynamics

Through the animal and vegetable kingdoms, nature has scattered the seeds of life abroad with the most profuse and liberal hand; but has been comparatively sparing in the room and nourishment necessary to rear them. T. R. Malthus Fifteen months after I had begun my systematic enquiry, I happened to read for amusement " Malthus on Population ". it at once struck me that. favorable variations would tend to be preserved, and unfavorable ones to be destroyed. Here, then, I had at last got a theory by which to work. Our study of evolutionary dynamics is built around the replicator equations. We begin by defining the replicator dynamic, deriving it in several distinct ways, and exploring its major characteristics (12.1–12.6). The next several sections make good on our promise to justify Nash equilibrium in terms of dynamical systems, as we exhibit the relationship between dynamic stability of evolutionary models, on the one hand, and dominated strategies (12.7), Nash equilibria (12.8), evolutionarily stable strategies (12.9), and connected sets of Nash equilibria, on the other. Many of the results we obtain remain valid in more general settings (e.g., when the dynamic has an aggregate tendency toward favoring more fit strategies, but not necessarily as strongly as the replicator dynamic). We next turn to asymmetric evolutionary games (12.17), which have the surprising property, a property that is extremely important from the point of view of understanding real-world evolutionary dynamics, that strictly mixed Nash equilibria are never asymptotically stable but are often neutrally stable, leading to generically stable orbits (the Lotka-Volterra model has orbits, but it is not generic, as small changes in the coefficients lead to the equilibrium being either a stable or an unstable focus). In asymmetric games, the limit points of dynamic processes are generally Nash equilib-271
Cytomorphological Evaluation And Thyroid Function Test (Tft) Analysis In Various Thyroid Diseases “Our Experience At Tertiary Care Centre”

Background – Aim of this study is to evaluate cytomorphological pattern and thyroid hormone profile analysis which provides information about physiological and pathological condition and help in the early detection of various thyroid diseases and there by reduces surgical intervention . Objectives – 1.To obtain the results of fine needle aspiration cytology (FNAC) and thyroid hormone profile in diagnosis of different benign lesions and neoplastic lesions. 2. confirmation of clinically diagnosed neoplastic lesions. Materials and Method – During the study period June 2013 to May 2014 Fine needle aspiration cytology (FNAC) was performed on 198 patients with clinical history of thyroid diseases Thyroid function test also performed whenever possible. Results –One ninety eight cases both males and females were analysed. Analysis of thyroid hormone profile was possible in 147 cases, age range in this study was 1-80 years. Most commonly affected age group was 3rd to 4th decades.There were 171 (86.36%)females and 27(13.64%) males.Most commonly encountered lesion was colloid goiter accounting for 101 cases. There were 188 non neoplastic lesions and 10 cases were found to be neoplastic.Maximum number of patients, 99 cases were euthyroid followed by hyperthyroid (22 cases) and hypothyroid (19 cases). Conclusion – Fine needle aspiration cytology (FNAC) and thyroid hormone profile are highly effective procedure for the assessment of patients with thyroid lesions. All type of thyroid lesions must be analysed in the light of clinical picture , FNAC and thyroid hormone profile to minimize the risk of false negative report. Early and accurate diagnosis of different thyroid lesions minimize surgical intervention and there by morbidity and mortality.
Investigating the Relationship Between Antisocial Personality Disorder and Malingering

Forensic patients with antisocial personality disorder (APD) were compared to forensic patients without APD on a validated measure of malingering (Structured Interview of Reported Symptoms [SIRS]). Results indicated that patients with APD were not significantly more likely to exceed accepted cutoff scores on the SIRS (i.e., 17.9% vs. 11.6%, respectively), nor were they more likely to be suspected of malingering by clinicians (17.9% vs. 18.6%). Although there was a high level of disagreement between clinicians’ determination of malingering and classification by the SIRS, this relationship was not significant. Furthermore, patients with APD who were suspected by clinicians to be malingering were not more likely to be classified as responding genuinely using the SIRS. These findings challenge the recommendation issued by the Diagnostic and Statistical Manual of Mental Disorders (4th ed., text revision) that advises clinicians to be highly suspicious of malingering in the presence of APD.
The Bacillus thuringiensis PlcR-Regulated Gene inhA2 Is Necessary, but Not Sufficient, for Virulence

ABSTRACT We previously reported that Bacillus thuringiensis strain 407 Cry 32− secretes a zinc-requiring metalloprotease, InhA2, that is essential for virulence in orally infected insects. Analysis of the inhA2-lacZ transcriptional fusion showed that inhA2 expression is repressed in a PlcR− background. Using DNase I footprinting experiments, we demonstrated that PlcR activates inhA2 transcription directly by binding to a DNA sequence showing a one-residue mismatch with the previously reported PlcR box. It was previously reported that PlcR is essential for B. thuringiensis virulence in oral infection by contributing to the synergistic properties of the spores on the insecticidal activity of the Cry1C protein. We used complementation experiments to investigate whether the PlcR− phenotype was due to the absence of InhA2. The results indicated that overexpression of inhA2 in the ΔplcR strain did not restore the wild-type phenotype. However, virulence was fully restored in the ΔinhA2 complemented mutant. Thus, inhA2 is the first example of a PlcR-regulated gene found to be directly involved in virulence. However, it is not sufficient for pathogenicity when the other members of the PlcR regulon are lacking. This suggests that InhA2 may act in concert with other PlcR-regulated gene products to provide virulence.
The Resurgence of Jihad & The Specter of Religious Populism

Global modernity has transformed the nature of religious belief and the practice of religion. One crucial change has been the resurgence of publicly active religious populism. However, policymakers and social scientists, burdened with a secularist bias, have failed to grasp the full nature of this phenomenon. A more complete understanding of contemporary religious populism can be attained by examining their distinctive narrative forms—that is, the way that they describe their worldview and fundamental goals. This article focuses on of one of the most extreme forms of religious populism: the global jihad.1 A cursory examination of this single case suggests that despite strong rhetorical similarities between the most prominent forms of religious populism, both at home and abroad, crucial differences persist in their political effects.
Three Management Challenges for Protection of Aboriginal Cultural Heritage in a Tasmanian Multiple-use Conservation Area

Abstract Protected areas that are created to safeguard environmental values such as Indigenous culturescapes may in fact significantly fail in this task. This study concerns such an instance in far north-west Tasmania, where the government adopted a multiple-use resource conservation-development management model for the Arthur–Pieman Conservation Area (APCA). The model offers protection of cultural heritage values whilst permitting numerous community recreational and commercial uses. One particular objective is to protect ‘an extraordinary richness of Aboriginal cultural heritage’ in one of Earth's great archaeological regions (DPIWE, Arthur–Pieman Conservation Area Management Plan, 2002, p. iii). Yet under the auspices of multiple use, Aborigine and others report unremitting damage and loss of ancestral values. To examine how this is so in an actively managed protected area, perceptions of 16 environmental professionals and local residents engaged in APCA planning and management are used to identify three major challenges for appropriate custodianship of the Aboriginal cultural landscape: Aboriginal–Eurocentric conflicts; limited community governance capacities; and deficient regulatory provisions. It is concluded that APCA multiple-use management of heritage conservation is ineffectual and that an alternative governance model is required urgently. The management challenges examined here offer insights for problematic Indigenous cultural heritage conservation in other jurisdictions of Australia and elsewhere.
Mütterliche Berufstätigkeit und kindliches Sozialverhalten

Der vorliegende Beitrag widmet sich den Auswirkungen der fruhen und der aktuellen mutterlichen Berufstatigkeit auf die Entwicklung des kindlichen Sozialverhaltens. Im Rahmen der Erlangen-Nurnberger Entwicklungs- und Praventionsstudie wurden in einem prospektiv langsschnittlichen Design 660 Kinder im Vorschulalter in funf Erhebungen uber einen Zeitraum von sechs Jahren untersucht. Das kindliche Verhalten wurde mittels Einschatzungen der Erzieherinnen, Lehrerinnen und Mutter im Social Behavior Questionnaire (SBQ; Tremblay et al., 1992) erfasst. Weder die fruhe noch die spatere Berufstatigkeit sowie deren Wechselwirkungen zeigten kurz- und langerfristige signifikante Zusammenhange mit dem Ausmas der kindlichen Erlebens- und Verhaltensprobleme. Es machte auch keinen Unterschied, ob die Mutter vollzeit- oder teilzeitbeschaftigt waren. Die Ergebnisse werden unter methodischen Gesichtspunkten und im Hinblick auf die ideologischen Auseinandersetzungen um Auswirkungen der (fruhen) mutterlichen Berufstatigkeit disk.
Treatment And Sexual Offence Recidivism

Cognitive-behavioral treatment has emerged as the principle type of sex offender treatment targeting deviant arousal, increasing appropriate sexual desires, modifying distorted thinking, and improving interpersonal coping skills. However, treatment effectiveness in reducing sexual offence recidivism continues to be questioned. This is despite the fact that since 1995, five meta-analytical studies have claimed positive treatment effects in reducing sexual offence recidivism. However, many treatment studies have been criticized for weaknesses in their methodologies. In addition, methodological differences between studies make it difficult to determine treatment efficacy. This review found that since 1995, 19 treatment studies have been published, and a third of the 18 studies demonstrating positive treatment effects used sound methodological techniques. Additional treatment studies are needed that utilize sound methodological principles to establish the most effective way of reducing sexual reoffending.