Miracle-dz/UniFAR-FTUs huggingface dataset:
What do scholarly channels and resources do authors trust to read, cite and publish in?: A Malaysian study

The paper provides the results of the first phase of the research project Trust and Authority in Scholarly Communications: The Periphery of World Scholarship in the Digital Era conducted in Malaysia. It provides for an examination of the behaviours and attitudes of academic researchers as producers and consumers of scholarly information resources in today's scholarly digital environment; with respect to how they determine authority and trustworthiness in the sources they use, cite, and publish in. This first phase utilised focus groups to obtain this information. Five focus groups were conducted in three universities in Kuala Lumpur involving a total of 48 science and social science researchers cum authors. Findings indicate that peer-reviewed journals are still the central to the authors, however they seem to have more freedom in relation to journals they read and cite, compared to publish. Overall, authors view that scholarly resources that are current, relevant, authored by credential scholars, peer-reviewed, having credible reference lists, published by reputable journals, and having online presence are fit for scholarly utilisation. The extent to which authors are prepared to believe that the scholarly information source and channel are trustworthy for publication rely on it in view of its impact, indexation status, reputation, peers' recommendation, accessibility and visibility, and authority's approval. New forms of communication channels such as social media or new journal models are not much used in formal scholarly communication or perhaps on the verge of being more used. The focus groups provided the direction for. questionnaires and interviews that would follow. The paper also discusses the implication of the findings to academic librarians towards delivering the right services to meet the needs of the scholarly community.
An online literature mining tool for protein phosphorylation

A web-based version of the RLIMS-P literature mining system was developed for online mining of protein phosphorylation information from MEDLINE abstracts. The online tool presents extracted phosphorylation objects (phosphorylated proteins, phosphorylation sites and protein kinases) in summary tables and full reports with evidence-tagged abstracts. The tool further allows mapping of phosphorylated proteins to protein entries in the UniProt Knowledgebase based on PubMed ID and/or protein name. The literature mining, coupled with database association, allows retrieval of rich biological information for the phosphorylated proteins and facilitates database annotation of phosphorylation features.
Powwer supply on chip (integration of inductors and capacitors with active semiconductors)

The paper introduces the concept of power supply on chip (PwrSoC) which will enable the development of next generation, functionally integrated, power management platforms with applications in dc-dc conversion, gate drives, isolated power transmission and ultimately, high granularity, on-chip, power management for mixed-signal, SOC chips. PwrSoC will integrate power passives with the power management IC, in a 3D stacked or monolithic form factor, thereby delivering the performance of a high efficiency dc-dc converter within the footprint of a low efficiency linear regulator. A central element of the PwrSoC concept is the fabrication of power micro-magnetics on silicon to deliver micro-inductors and micro-transformers. The paper details the magnetics on silicon process which combines thin film magnetic core technology with electroplated copper conductors. Measured data for micro-inductors show inductance operation up to 20MHz, footprints down to 0.5mm2, efficiencies up to 93% and dc current carrying capability up to 600mA. Measurements on micro-transformers show voltage gain of approximately -1dB at between 10MHz and 30 MHz.
Magnetization transfer effects in multislice RARE sequences

Magnetization transfer effects are demonstrated to be significant in determining the signal intensity from brain tissues on images acquired with multislice rapid acquisition relaxation enhanced (RARE) sequences. We report studies designed to determine how the signal intensities vary with slice number or, equivalently, off‐resonance power deposition. The results obtained in fat, gray matter, and white matter are similar in form to those reported in kidney tissues during classic magnetization transfer experiments (J. Eng, T. L. Ceckler, and R. S. Balaban, Magn. Reson. Med. 17,304 (1991)). Of clinical significance to RARE practitioners is the increase of contrast‐to‐noise ratios between gray and white matter on proton density‐weighted images with increasing slice number. © 1992 Academic Press, Inc.
Involving the Entrepreneurial Role Model: A Possible Development for Entrepreneurship Education

This paper offers and discusses an alternative way to delivering entrepreneurship education to students in higher education institutions through the involvement of a role model(s) in entrepreneurship teaching and learning. A previous study with students in an Indonesian university showed that the role model is in position to give positive influence to their entrepreneurial motivation, and furthermore, the choice for a future career as an entrepreneur. As a further development, this paper outlines a model whereby the appropriate role of the dominant entrepreneurial role models (who are parents, entrepreneurs and teachers/lecturers) are integrated one with the other and can be used as a source of an entrepreneurial learning process. The lecturer can take on the major task as the facilitator to encourage students to seek the appropriate knowledge about entrepreneurship in this integration whilst the other two constructs can take on their major tasks to act as sources of informal entrepreneurial learning (through social and active learning). Entrepreneurs in particular, can act as a 'business father or mother' to whom students can talk and with whom they can establish a longer infonnal relationship. This paper argues that whilst this model can be implemented successfully it is critical that a suitable and proper institutional setting -in terms of curriculum arrangement -alongside the availability of supporting facilities and infrastructures be arranged and addressed to support it. © 2014 by Jordan Whitney Enterprises, Inc, USA
Driving Behavior of Alcohol, Cannabis, and Cocaine Abuse Treatment Clients and Population Controls

Background/Introduction: A paucity of research exists on driving after use of cannabis or cocaine among clients in substance abuse treatment and changes in this behavior after treatment. Objectives: The objectives of this research are to compare treatment clients and population controls before and after treatment in terms of: 1) amount of driving; 2) alcohol, cannabis, and cocaine consumption; 3) driving after use of alcohol, cannabis, and cocaine; and 4) driving infractions. Method: Telephone interviews were conducted with a sample of 110 clients who received treatment in 1995 for a primary problem of alcohol (n = 44), cannabis (n = 37), or cocaine (n = 29) abuse. A random sample of 104 drivers from the general population, frequency matched by age and sex was also interviewed. Participants were asked to describe their driving habits and driving infractions before and after 1995. Results: Both treatment and control groups reported about the same amount of driving. The treatment group reported significantly more consumption of alcohol, cannabis, and cocaine than did the control group before treatment. Significant declines in use for each substance were found for the treatment group after treatment, but use for the control group remained stable over the two time periods. Similarly significant declines in driving after use of alcohol, cannabis, and cocaine were found for the treatment group but the control group remained stable. Finally driving infractions, including speeding tickets, collisions, and license suspensions, significantly declined for the treatment group but not the control group. Discussion: The results confirm that before treatment, the treatment subjects drove more frequently after consuming alcohol, cannabis, or cocaine than the control group. Declines in substance use and driving after treatment were accompanied by reductions in some types of driving infractions. Differences between groups, and over time in terms of driving while under the influence of psychoactive substances better explain the results than differences between groups in impulsivity/risk‐taking or sleep problems.
Molecular and clinical analysis of locally advanced dermatofibrosarcoma protuberans treated with imatinib: Imatinib Target Exploration Consortium Study B2225.

PURPOSE The cutaneous malignant tumor dermatofibrosarcoma protuberans (DFSP) is typically associated with a translocation between chromosomes 17 and 22 that places the platelet-derived growth factor-B (PDGFB) under the control of the collagen 1A1 promoter. The purpose of this study was to evaluate molecular, cytogenetic, and kinase activation profiles in a series of DFSPs and to determine whether these biologic parameters are correlated with the clinical responses of DFSP to imatinib. PATIENTS AND METHODS We analyzed the objective radiologic and clinical response to imatinib at 400 mg twice daily in eight patients with locally advanced DFSP and two patients with metastatic disease. RESULTS Each of eight patients with locally advanced DFSP had evidence of t(17;22) and showed a clinical response to imatinib. Four of these patients had complete clinical responses. The two patients with metastatic disease had fibrosarcomatous histology and karyotypes that were substantially more complex than those typically associated with localized DFSP. One patient with metastatic DFSP and an associated t(17;22) had a partial response to imatinib but experienced disease progression after 7 months of therapy. In contrast, the other patient with metastatic disease had a tumor lacking t(17;22), and there was no clinical response to imatinib. Unexpectedly, there was minimal platelet-derived growth factor receptor-beta phosphorylation in the untreated DFSP, despite the documented presence of a PDGFB autocrine mechanism. CONCLUSION Imatinib has clinical activity against both localized and metastatic DFSP with t(17;22). However, fibrosarcomatous variants of DFSP lacking t(17;22) may not respond to imatinib.
Molecular alterations in the neostriatum of human cocaine addicts

Molecular changes in the neostriatum of human subjects who died with a history of cocaine abuse were revealed in discrete cell populations by means of the techniques of in situ hybridization histochemistry and in vitro receptor binding and autoradiography. Cocaine subjects had a history of repeated cocaine use and had cocaine and/or cocaine metabolites on board at the time of death. These subjects were compared to control subjects that had both a negative history and toxicology of cocaine use. Selective alterations in mRNA levels of striatal neuropeptides were detected in cocaine subjects compared to control subjects, especially for the opioid peptides. Marked reductions in the levels of enkephalin mRNA and μ opiate receptor binding were found in the caudate and putamen, concomitant with elevations in levels of dynorphin mRNA and κ opiate receptor binding in the putamen and caudate, respectively. Dopamine uptake site binding was reduced in the caudate and putamen of cocaine subjects. The greater magnitude of changes in the dorsolateral striatum (caudate and putamen) as opposed to the ventromedial striatum (nucleus accumbens) suggests that cocaine abuse preferentially alters the biosynthetic activity of striatal systems associated with sensorimotor functioning. Additionally, an imbalance in the activity of the two major striatal output pathways in cocaine users is implicated because peptide mRNA levels were reduced in enkephalinergic striatopallidal neurons and increased in dynorphinergic striatonigral neurons. Another imbalance, that of reductions of transmitter mRNA and receptor expression associated with euphoria (enkephalin and μ opiate receptors), together with elevations in mRNAs of transmitter systems associated with dysphoria (dynorphin and κ opiate receptors), suggests a model of dysphoria and craving in the human cocaine addict brain. © 1993 Wiley‐Liss, Inc.
Supervisory fault tolerant control of the NASA AirStar aircraft

A multi-level reconfiguration framework is proposed for fault tolerant control of overactuated aerial vehicles, where the levels indicate how much authority is given to the reconfiguration task. On the lowest, first level the fault is accommodated by modifying only the actuator/sensor configuration, so the fault remains hidden from the baseline controller. A dynamic reallocation scheme is applied on this level. The allocation mechanism exploits the actuator/sensor redundancy available on the aircraft. In case the fault cannot be managed at the actuator/sensor level the reconfiguration process has access the baseline controller. Based on the LPV control framework, this is done by introducing fault-specific scheduling parameters. The baseline controller is designed to provide acceptable performance level along all fault scenarios coded in these scheduling variables. The decision of which reconfiguration level has to be initiated in response to a fault is determined by a supervisor unit. The method is demonstrated on the full six degrees of freedom nonlinear simulation model of the GTM UAV.
A 0‐Hour/1‐Hour Protocol for Safe, Early Discharge of Chest Pain Patients

OBJECTIVES Guidelines recommend a 0-hour/1-hour high-sensitivity cardiac troponin T (hs-cTnT) diagnostic strategy in acute chest pain patients. There are, however, little data on the performance of this strategy when combined with clinical risk stratification. We aimed to evaluate the diagnostic accuracy of an accelerated diagnostic protocol (ADP) using the 0-hour/1-hour hs-cTnT strategy together with an adapted Thrombolysis In Myocardial Infarction (TIMI) score and electrocardiogram (ECG) for ruling out major adverse cardiac events (MACE) within 30 days. METHODS This prospective observational study enrolled consecutive emergency department (ED) chest pain patients. TIMI score variables, ED physicians' assessments of the ECG, and 0- and 1-hour hs-cTnT were collected. Thirty-day MACE was defined as acute myocardial infarction (AMI), unstable angina (UA), cardiogenic shock, ventricular arrhythmia, atrioventricular block, cardiac arrest, or death of cardiac or unknown cause. RESULTS A total of 1,020 patients were included in the final analysis. The combination of an adapted TIMI score ≤1, a nonischemic ECG, and either a 0-hour hs-cTnT < 5 ng/L or a 0-hour hs-cTnT < 12 ng/L combined with a 1-hour increase < 3 ng/L identified 432 (42.4%) patients as very low risk with a negative predictive value of 99.5% (95% confidence interval [CI] = 98.3%-99.9%) and a negative likelihood ratio of 0.04 (95% CI = 0.01-0.14) for 30-day MACE. The ADP missed only two patients with UA and no patients with AMI or other forms of MACE. CONCLUSION An ADP using the guideline recommended 0-hour/1-hour hs-cTnT strategy rapidly identified patients with a very low risk of 30-day MACE including UA where no further cardiac testing would be needed. This could potentially allow safe early discharge of about 40% of ED chest pain patients.
Three-dimensional indoor localisation system using radio frequency identification tags

Radio Frequency Identification (RFID) is an information exchange technology based on radio wave communication. It is also a possible solution to indoor localisation. Owing to multipath propagation and anisotropic interference in the indoor environment, theoretical propagation models are generally not sufficient for RFID-based localisation. In fact, the received radio frequency signal distribution may not even be monotonic and this makes range-based localisation algorithms less accurate. On the other hand, range-free localisation algorithms, such as k Nearest-Neighbour (kNN), require reference tags to be spread throughout the whole three-dimensional (3D) space which is frequently not practical. In this work, a hybrid real-time localisation algorithm that combines reference tags with Received Signal Strength Indicator (RSSI) ranging is introduced to improve RFID-based 3D localisation in indoor environments. The localisation algorithm is implemented in MATLAB and is synchronised with radio signal data in real-time. Results show that the proposed hybrid algorithm achieves an average 3D localisation error of 1.08 m which represents a significant improvement over algorithms that use only kNN or RSSI.
Application of compressive sensing for distributed and structured power line outage detection in smart grids

Fast and accurate identification and localization of power line outages is one of the critical issues for efficient monitoring and control tasks in future smart grids. In this work, considering the whole power network (PN) as a single graph, the recently introduced sparse formulation of the Power line Outage Identification (POI-SRP) is represented. Our main contribution is to improve and generalize the POI-SRP results for single and multiple line outage identification using matrix analysis and the structured pattern in multiple POI. We address the high coherence and high correlation issues in corresponding POI-SRP sensing matrices. In order to solve these problems, we perform a comprehensive study on the corresponding matrices of the IEEE standard networks in POI-SRP. Our main approach will be based on the necessary and sufficient conditions that these matrices should satisfy in order to be applicable to the Sparse Recovery Problem (SRP). First, we discuss the effect that node-line connection structures in the PN model have on the coherence. We describe a modification of the PN model in order to decrease the coherence. Next, using the IEEE standard 118-BUS as a case study, we discuss how the high correlation problem can be solved by applying mathematical matrix analysis such as matrix decomposition and improving the final POI results. The third main contribution is the identification of the structured outages in POI-SRP. In this work, the boundary conditions of the Clustered OMP recovery algorithm are modified (MCOMP) and finally it will be shown how the existence of structured sparsity in multiple POI problems (Structured-POI-SRP) helps MCOMP to improve the POI results.
Invisible Punishment: An Instrument of Social Exclusion

As the rates of imprisonment and criminal justice supervision have grown in America, another form of criminal sanction, the network of laws that limit the rights and privileges of ex-offenders, has also increased. These sanctions, called invisible punishment, range from barriers to public housing for drug offenders to lifetime registration requirements for sex offenders. This book chapter describes the varieties of invisible punishment in modern America and the recent growth in these laws. The chapter argues that these sanctions reduce the chances of successful reintegration for ex-offenders and proposes a reform strategy.
COL4A3/COL4A4 mutations: from familial hematuria to autosomal-dominant or recessive Alport syndrome.

UNLABELLED COL4A3/COL4A4 mutations: From familial hematuria to autosomal-dominant or recessive Alport syndrome. BACKGROUND Mutations of the type IV collagen COL4A5 gene cause X-linked Alport syndrome (ATS). Mutations of COL4A3 and COL4A4 have been reported both in autosomal-recessive and autosomal-dominant ATS, as well as in benign familial hematuria (BFH). In the latter conditions, however, clinical features are less defined, few mutations have been reported, and other genes and non-genetic factors may be involved. METHODS We analyzed 36 ATS patients for COL4A3 and COL4A4 mutations by polymerase chain reaction-single strand conformational polymorphism (PCR-SSCP) and direct sequencing. Sporadic patients who had tested negative for COL4A5 mutations were included with typical cases of autosomal recessive ATS to secure a better definition of the phenotype spectrum. RESULTS We identified seven previously undescribed COL4A3 mutations: in two genetic compounds and three heterozygotes, and one in COL4A4. In agreement with the literature, some of the mutations of compound heterozygotes were associated with microhematuria in healthy heterozygous relatives. The mutations of heterozygous patients are likely dominant, since no change was identified in the second allele even by sequencing, and they are predicted to result in shortened or abnormal chains with a possible dominant-negative effect. In addition, both genes showed rare variants of unclear pathogenicity, and common polymorphisms that are shared in part with other populations. CONCLUSIONS This study extends the mutation spectrum of COL4A3 and COL4A4 genes, and suggests a possible relationship between production of abnormal COL IV chains and dominant expression of a continuous spectrum of phenotypes, from ATS to BFH.
Guidance for the classification of carcinogens under the Globally Harmonised System of Classification and Labelling of Chemicals (GHS)

The United Nations Conference on Environment and Development (UNCED) has developed criteria for a globally harmonised system of classification and labelling of chemicals (GHS). With regard to carcinogenicity, GHS distinguishes between Category 1 (‘known or presumed human carcinogens’) and Category 2 (‘suspected human carcinogens’). Category 1 carcinogens are divided into Category 1A (‘known to have carcinogenic potential for humans’), based largely on human evidence, and 1B (‘presumed to have carcinogenic potential for humans’), based largely on experimental animal data. Concerns have been raised that the criteria for applying these carcinogenicity classifications are not sufficiently well defined and potentially allow different conclusions to be drawn. The current document describes an attempt to reduce the potential for diverse conclusions resulting from the GHS classification system through the application of a series of questions during the evaluation of data from experiments with rodents; epidemiological data, which could lead to Category 1A, have not been considered. Answers to each question can lead either to a classification decision or to the next question, but this process should only be implemented in an environment of informed scientific opinion. The scheme is illustrated with five case studies. These questions are: (1) Has a relevant form of the substance been tested? (2) Is the study design relevant to human exposure? (3) Is there a substance-related response? (4) Is the target tissue exposure relevant to humans? (5) Can a mode of action be established? (6) Is the mode of action relevant to humans? (7) What is the potency?