Miracle-dz/UniFAR-FTUs huggingface dataset:
Abstract: -this Paper Describes Some of the Results and Algorithms from the Development of a Compiler Utility for an Architecture

Description Language π-ADL, for the . NET platform. Architecture Description Languages or ADLs, are special purpose high level languages especially construed to define software architectures. π-ADL, a recent addition to this class of languages, is formally based on the π-Calculus, a process oriented formal method. The compiler for π-ADL, named π-ADL.NET, is designed with the view of bringing the architecture driven software design approach to the . NET platform. The process oriented nature and a robust set of parallelism constructs of π-ADL make the π-ADL.NET project a novel application of compiler techniques in the context of the . NET platform, with many valuable lessons learnt. This paper presents the π-ADL.NET effort from a compiler design perspective, and also documents the motivation, vision and future possibilities for this line of work.
UWB Band-Notched Monopole Antenna Design Using Electromagnetic-Bandgap Structures

A new approach is proposed to reject certain bands within the passband of an ultra-wideband planar monopole antenna. The proposed approach that utilizes a mushroom-type electromagnetic-bandgap (EBG) structure is proven to be an effective way for band-notched designs. The approach has many advantages, such as notch-frequency tunability, notch-band width controllable capacity, efficient dual-notch design, and stable radiation patterns. Several design examples using conventional mushroom-type EBG and edge-located vias mushroom-type EBG are presented. The examples exhibit good bandstop characteristics to reject the wireless local-area network interference bands (5.2- and 5.8-GHz bands). Besides, the causes that lead to the discrepancies between the simulations and measurements are discussed.
The epidemiology of thyroid disease.

INTRODUCTION Thyroid disorders are prevalent and their manifestations are determined by the dietary iodine availability. SOURCES OF DATA Data from screening large population samples from USA and Europe. AREAS OF AGREEMENT The most common cause of thyroid disorders worldwide is iodine deficiency, leading to goitre formation and hypothyroidism. In iodine-replete areas, most persons with thyroid disorders have autoimmune disease. AREAS OF CONTROVERSY Definition of thyroid disorders, selection criteria used, influence of age and sex, environmental factors and the different techniques used for assessment of thyroid function. GROWING POINTS Increasing incidence of well-differentiated thyroid cancer. Environmental iodine influences the epidemiology of non-malignant thyroid disease. AREAS TIMELY FOR DEVELOPING RESEARCH Iodine supplementation of populations with mild-to-moderate iodine deficiency. An evidence-based strategy for the risk stratification, treatment and follow-up of benign nodular thyroid disease. Is there any benefit in screening adults for thyroid dysfunction?
Analogic Preprocessing And Segmentation Algorithms For Offline Handwriting Recognition

This report describes analogic algorithms used in the preprocessing and segmentation phase of offline handwriting recognition tasks. A segmentation-based handwriting recognition approach is discussed, i.e., the system attempts to segment the words into their constituent letters. In order to improve their speed, the utilized CNN algorithms, whenever possible, use dynamic, wave front propagation-based methods instead of relying on morphologic operators were embedded into iterative algorithms. The system first locates the handwritten lines in the page image, then corrects their skew as necessary. It then searches for the words within the lines and corrects the skew at the word level as well. A novel trigger wave-based word segmentation algorithm is presented, which operates on the skeletons of words. Sample results of experiments conducted on a database of 25 handwritten pages along with suggestions for future development are presented.
Why Are Some Diagrams Easier to Work With? : Effects of Diagrammatic Representation on the Cognitive Integration Process of Systems Analysis and Design

Various diagrams have been used heavily in systems analysis and design without proper verification of their usability. However, different diagrammatic representations of the same information may vary in the computational efficiency of working with these diagrams. The objective of this research was to explore the effects of diagrammatic representations on the task of integrating multiple diagrams. The domain of systems analysis and design was used to generate examples and test the theory. A cognitive model of diagram integration was proposed, and an experimental study was conducted to explore the effects of representational features of diagrams on the cognitive process of diagram integration. Results of the experiment show that the representational features of the diagrams acted as the criteria for selecting among various methods for analyzing and designing the integrated diagram. In addition, the difference in the selected methods resulted in different task performances in terms of analysis and design errors. This paper concludes with the implications of the results for the development of cognitively compelling diagrams.
The pan-PI3K inhibitor GDC-0941 activates canonical WNT signaling to confer resistance in TNBC cells: resistance reversal with WNT inhibitor

The pan-PI3K inhibitors are one treatment option for triple-negative breast cancer (TNBC). However, this treatment is ineffective for unknown reasons. Here, we report that aberrant expression of wingless-type MMTV integration site family (WNT) and activated WNT signals, which crosstalk with the PI3K-AKT-mTOR signaling pathway through GSK3β, plays the most critical role in resistance to pan-PI3K inhibitors in TNBC cells. GDC-0941 is a pan-PI3K inhibitor that activates the WNT/beta-catenin pathway in TNBC cells through stimulation of WNT secretion. GDC-0941-triggered WNT/beta-catenin pathway activation was observed in MDA-MB-231 and HCC1937 cells, which are TNBC cell lines showing aberrant WNT/beta-catenin activation, and not in SKBR3 and MCF7 cells. This observation is further investigated in vivo. GDC-0941 exhibited minimal tumor inhibition in MDA-MB-231 cells, but it significantly suppressed tumor growth in HER-positive SK-BR3 cells. In vivo mechanism study revealed the activation of WNT/beta-catenin pathway by GDC-0941. A synergistic effect was observed when combined treatment with GDC-0941 and the WNT inhibitor LGK974 at low concentrations in MDA-MB-231 cells. These findings indicated that WNT pathway activation conferred resistance in TNBC cells treated with GDC-0941. This resistance may be further circumvented through combined treatment with pan-PI3K and WNT inhibitors. Future clinical trials of these two inhibitors are warranted.
A Taxonomy of Scheduling Algorithms for Cloud Computing

Cloud Computing or simply rental computing, is a new technology currently being studied in the academic world and broadly categorized as Infrastructure as a Service (IaaS), Platform as a Service (PaaS) and Software as a Service (SaaS). Virtualization is the backbone of cloud computing and scalable, dynamic resources can be effectively managed using virtualization technology. It is possible to remap virtual machines (VMs) and physical resources according to the change in load with the help of heuristics. In this paper we present some of the most commonly used workflow heuristics currently being used in a cloud environment.
Research on spontaneous activity in adult anisometropic amblyopia with regional homogeneity

Amblyopia usually occurs in early childhood and results in monocular visual impairment. The functional magnetic resonance imaging (fMRI) studies have reflected functional anomaly in amblyopia. In resting-state fMRI study, spontaneous activity changes abnormally in anisometropic amblyopia could be revealed by the regional homogeneity (ReHo). Twenty two adult anisometropic amblyopes and Twenty one normal controls participated in this fMRI study. Two sample T test was carried out to analysis ReHo within the whole brain for the inter groups. Compare with normal group, our study found that the amblyopia’s ReHo mainly increased in the left frontal lobe, while decreased in the left cerebellum, the temporal lobe (left and right), and the left parietal lobe. And the ReHo values in middle and inferior temporal lobe, the prefrontal lobe, frontal lobe (positive) and parietal lobe and medial frontal gyrus (negative) could be correlated with the acuity deficit of amblyopia. The results increased in ReHo may indicate compensatory plasticity in higher vision information process, while the decreased in ReHo may reflect decreased ability in eye movement, spatial sense and visuo-motor coordination. The correlation revealed that the vision deficit may correspond to the spontaneous in certain brain area.
Eype-Using Eye-Traces for Eye-Typing

Copyright is held by the author/owner(s). CHI’13 Workshop on Grand Challenges in Text Entry, April 28, 2013, Paris, France. Abstract Current eye-typing systems are suffering from the needed dwell timeout which limits the possible entry rate. In this position paper we discuss how the usage of eye-traces on on-screen keyboards could be used for almost dwell timeout free gaze based communication. This could significantly increase the entry rate of eye-typing systems.
Patch-Graph Reconstruction for Piecewise Smooth Surfaces

In this paper we present a new surface reconstruction technique for piecewise smooth surfaces from point clouds, such as scans of architectural sites or man-made artifacts. The technique operates in three conceptual steps: First, a graph of local surface patches, each consisting of a set of basis functions, is assembled. Second, we establish topological connectivity among the nodes that respects sharp features. Third, we find optimal coefficients for the basis functions in each node by solving a sparse optimization problem. Our final representation allows for robust finding of crease and border edges which separate the piecewise smooth parts. As output of our approach, we extract a clean, manifold surface mesh which preserves and even aggravates feature lines. The main benefit of our new proposal in comparison to previous work is its robustness and efficiency, which we examine by applying the algorithm to a variety of different synthetic and realword data sets.
A Protein Phosphatase 2c, Responsive to the Bacterial Effector Avrrpm1 but Not to the Avrb Effector, Regulates Defense Responses in Arabidopsis

SUMMARY Using a proteomics approach, a PP2C-type phosphatase (renamed PIA1, for PP2C induced by AvrRpm1) was identified that accumulates following infection by Pseudomonas syringae expressing the type III effector AvrRpm1, and subsequent activation of the corresponding plant NB-LRR disease resistance protein RPM1. No accumulation of PIA1 protein was seen following infection with P. syringae expressing AvrB, another type III effector that also activates RPM1, although PIA transcripts were observed. Accordingly, mutation of PIA1 resulted in enhanced RPM1 function in response to P. syringae pathover tomato (Pto) DC3000 (avrRpm1) but not to Pto DC3000 (avrB). Thus, PIA1 is a protein marker that distinguishes AvrRpm1-and AvrB-dependent activation of RPM1. AvrRpm1-induced expression of the pathogenesis-related genes PR1, PR2 and PR3, and salicylic acid accumulation were reduced in two pia1 mutants. By contrast, expression of other defense-related genes, including PR5 and PDF1.2 (plant defensin), was elevated in unchallenged pia1 mutants. Hence, PIA1 is required for AvrRpm1-induced responses, and confers dual (both positive and negative) regulation of defense gene expression.
On applications for dynamically shared circuit-switched / virtual-circuit networks

Generalized MultiProtocol Label Switched (GMPLS) control-plane protocols have been standardized to enable dynamic call-by-call bandwidth sharing in circuit-switched/virtual-circuit (VC) networks. Most GMPLS control-plane implementations within controller cards of circuit/VC switches only support an immediate-request mode of bandwidth sharing because the signaling protocols within the GMPLS control-plane protocol suite do not have parameters needed for advance reservations, such as future start time. This paper addresses the question of suitability of applications for such networks, i.e., circuit/VC networks with the immediate-request mode of bandwidth sharing. Two types of applications are considered, ones in which the per-circuit bandwidth and call holding time are independent and ones in which they are dependent (file transfers). This work, through analysis, reasons that amongst the first type of applications, both short-duration applications that require high-bandwidth circuits relative to the link capacity (e.g., where the ratio is one-tenth, say 1 Gb/s circuits on a 10 Gb/s link) and applications that require on the order of one-hundredth the link capacity as per-circuit rates, are suitable for immediaterequest circuit/VC networks. For file transfers, we show that there is value to adding an immediaterequest circuit/VC network to complement the connectionless Internet, and directing “elephant” (largesized) file transfers to the circuit/VC network. We created a hybrid model, combining the ErlangB callblocking model with TCP delay models. Using this hybrid model, we studied the question of what sized files to direct to the circuit/VC network, and how much bandwidth to allocate on the circuit/VC network per (large) file transfer. Our answers are to direct files larger than a crossover file size, χ, determined by a combination of utilization and delay considerations, and to use a heterogeneous scheme with high per-circuit bandwidth allocations for larger files and lower values for (relatively) smaller files.
Silicon Active Microvalves Using Buckled Membranes For Actuation

Design considerations and experiments have been made for obtaining a new type of active microvalves using silicon buckled membranes. The properties of the buckled membranes permitting to obtain high deflections and to actuate them more convenient are demonstrated. A thermal actuation using an aluminium ring layer heated with a polysilicon resistor is analysed. The polysilicon and the aluminium ring layers have been deposited In the region of the membrane having the minimum internal stress. The fabrication process consist of photolithography, LPCVD depositions, diffusion, Al sputtering. isotropic, anisotropic etching and anodic bonding. The design and experiments show a convenient low temperature range necessary to actuate the microvalve.
Assessment of HVDC grid segmentation for reducing the risk of cascading outages and blackouts

This paper deals with a DC-segmentation of interconnected power systems which represents a relatively new and interesting approach that could be a potential solution for mitigation of the cascading outages effects. The DC-segmentation is defined as the use of DC links to split large AC grids into sets of smaller asynchronously operated AC segments. By implementing grid segmentation, it should be plausible to improve the controllability of power flows, to limit the propagation of disturbances, to reduce the risk of cascading outages and blackouts and to decrease the complexity of power systems. The statistical analysis of time series of blackouts size measures demonstrates the power law region in distributions of different quantities. This heavy tail behavior implies that the blackouts of different scales may take place and the extreme events cannot be overlooked. In order to take into account the risk of large blackouts, a new risk assessment method is developed and implemented. This method is based on Monte Carlo Simulation and takes into account the cascading outages of transmission system due to the overloading and the hidden failure of protection systems and the response of generators/loads/HVDC controllers to the power imbalance or the frequency deviation. The effectiveness of the DC-segmentation for reducing the risk of large blackouts is assessed using the proposed risk assessment method applied to a simplified model of the potential future intercontinental power grid of Europe and Russia. The distributions and expected values of the blackout size quantities (including Load Not Served (LNS), Number of Transmission component Outage (NTO) and Energy Not Served (ENS)) are evaluated before and after the DC-segmentation.
The asymptotics of optimal (equiripple) filters

For equiripple filters, the relation among the filter length N+1, the transition bandwidth /spl Delta//spl omega/, and the optimal passband and stopband errors /spl delta//sub p/ and /spl delta//sub s/ has been a secret for more than 20 years. This paper is aimed at solving this mystery. We derive the exact asymptotic results in the weight-free case /spl delta//sub p/=/spl delta//sub s/=/spl delta/, which enables us to interpret and improve the existing empirical formulas. Our main results are finally combined into a formula. In the transition band, the filter response is discovered to be asymptotically close to a scaled error function. The main tools are potential theory in the complex plane and asymptotic analysis.
Joint decision-directed beamforming and channel equalization approach for OFDM systems

In this paper, a joint decision-directed beamforming and channel equalization approach is presented for OFDM systems in the presence of co-channel interference (CCI). According to the minimum mean-square error (MMSE) criterion, the cost function of the joint approach is proposed to minimize the MSE on each subchannel and to further improve the system performance. The joint approach is a dual-loop structure composed of a beamforming and a channel equalization loops. The beamforming loop is primarily employed to suppress CCI. The channel equalization loop is used to compensate the baseband equivalent channel variations caused by multipath fading channel and adaptation of beamformer. The simulations are done for the multipath frequency-selective fading channel with CCI to show that the proposed approach can effectively eliminate CCI and compensate the channel distortions, thereby enhancing the system performance compared with the considered pilot-aided approach.
The Directed Differentiation of Human iPS Cells into Kidney Podocytes

The loss of glomerular podocytes is a key event in the progression of chronic kidney disease resulting in proteinuria and declining function. Podocytes are slow cycling cells that are considered terminally differentiated. Here we provide the first report of the directed differentiation of induced pluripotent stem (iPS) cells to generate kidney cells with podocyte features. The iPS-derived podocytes share a morphological phenotype analogous with cultured human podocytes. Following 10 days of directed differentiation, iPS podocytes had an up-regulated expression of mRNA and protein localization for podocyte markers including synaptopodin, nephrin and Wilm’s tumour protein (WT1), combined with a down-regulation of the stem cell marker OCT3/4. In contrast to human podocytes that become quiescent in culture, iPS-derived cells maintain a proliferative capacity suggestive of a more immature phenotype. The transduction of iPS podocytes with fluorescent labeled-talin that were immunostained with podocin showed a cytoplasmic contractile response to angiotensin II (AII). A permeability assay provided functional evidence of albumin uptake in the cytoplasm of iPS podocytes comparable to human podocytes. Moreover, labeled iPS-derived podocytes were found to integrate into reaggregated metanephric kidney explants where they incorporated into developing glomeruli and co-expressed WT1. This study establishes the differentiation of iPS cells to kidney podocytes that will be useful for screening new treatments, understanding podocyte pathogenesis, and offering possibilities for regenerative medicine.
Socioeconomic inequalities in the use of delivery care services in Bangladesh : a comparative study between 2004 and 2007

The study explores inequalities in the utilization of delivery care services in different administrative divisions in Bangladesh, by key socioeconomic factors. It estimates the extent of the relationship between women’s socioeconomic inequalities and their place of delivery during 2004 and 2007. Trends in relation to place of delivery in relation to residency and education over a period of thirteen years (1993-2007) have also been measured. The study analyzed the trends and patterns in utilization of institutional delivery care among mothers, using data from the Bangladesh Demographic Health Survey (BDHS) conducted during 1993-2007. The data was disaggregated by area of residence in different divisions in Bangladesh. Bi-variate analyses, concentration curves and multivariate logistic regression were employed in the analysis of the data. The study indicated slow progress in the utilization of institutional delivery care among mothers in Bangladesh between 1993 and 2007. Large variations in outcome measures were observed among the different divisions. Multivariate analyses suggested growing inequalities in utilization of delivery care services between different economic groups and parents with different educational levels. The use of institutional delivery care remains substantially lower among poor and less educated rural mothers in Bangladesh, irrespective of age and employment. Further studies are recommended to explore the specific causes relating to the non-utilization of institutional delivery care.
Nanoplatforms for magnetic resonance imaging of cancer

Summary The application of biomedical nanotechnology in magnetic resonance imaging (MRI) is expect to have a major impact leading to the development of new contrast drug candidates on the nanoscale (1–100 nm) that are able to react with specific biological targets at a molecular level. One of the major challenges in this regard is the construction of nanomaterials, especially used in molecular MRI diagnostics of cancer in vivo, specialized antitumor drug delivery or real-time evaluation of the efficacy of the implemented cancer treatment. In this paper, we tried to gain further insights into current trends of nanomedicine, with special focus on preclinical MRI studies in translation cancer research.
Advances in the automatic transcription of lectures

Transcribing lectures is a challenging task, both in acoustic and in language modeling. In this work, we present recent results on the automatic transcription of lectures from the Translanguage English Database, which contains the recordings of talks given in English at Eurospeech '93, by mostly non-native speakers. Concerning acoustic modeling, the acoustic model trained for a broadcast news transcription task was adapted on the lectures training data through maximum likelihood linear regression adaptation, including models of spontaneous speech phenomena. Moreover, a normalization procedure was embodied in the training stage, consisting of a cluster-based mean and variance normalization of the static features. Language modeling was based on adaptation of a background language model estimated on broadcast news transcripts, conference proceedings, lecture transcripts, and conversational speech transcripts. Among the examined adaptation techniques, the most effective one was obtained by exploiting the paper presented in each lecture to be processed. The best transcription performance on a 2 hours test set was 32.4% word error rate.
On The Vertex Folkman Numbers $F_v(\underbrace{2,...,2}_r;r-1)$ and $F_v(\underbrace{2,...,2}_r;r-2)$%

For a graph G the symbol G v −→ (a1, . . . , ar) means that in every r-coloring of the vertices of G, for some i ∈ {1, 2, . , r}, there exists a monochromatic ai-clique of color i. The vertex Folkman numbers Fv(a1, . . . , ar; q) = min{|V (G)| : G v −→ (a1, . . . , ar) and Kq * G} are considered. We prove that Fv(2, . . . , 2 | {z } r ; r − 1) = r + 7, r ≥ 6 and Fv(2, . . . , 2 | {z } r ; r − 2) = r + 9, r ≥ 8.