Miracle-dz/UniFAR-FTUs huggingface dataset:
Commitment to COT verification improves patient outcomes and financial performance.

BACKGROUND After an unsuccessful American College of Surgery Committee on Trauma visit, our level I trauma center initiated an improvement program that included (1) hiring new personnel (trauma director and surgeons, nurse coordinator, orthopedic trauma surgeon, and registry staff), (2) correcting deficiencies in trauma quality assurance and process improvement programs, and (3) development of an outreach program. Subsequently, our trauma center had two successful verifications. We examined the longitudinal effects of these efforts on volume, patient outcomes and finances. METHODS The Trauma Registry was used to derive data for all trauma patients evaluated in the emergency department from 2001 to 2007. Clinical data analyzed included number of admissions, interfacility transfers, injury severity scores (ISS), length of stay, and mortality for 2001 to 2007. Financial performance was assessed for fiscal years 2001 to 2007. Data were divided into patients discharged from the emergency department and those admitted to the hospital. RESULTS Admissions increased 30%, representing a 7.6% annual increase (p = 0.004), mostly due to a nearly fivefold increase in interfacility transfers. Severe trauma patients (ISS >24) increased 106% and mortality rate for ISS >24 decreased by 47% to almost half the average of the National Trauma Database. There was a 78% increase in revenue and a sustained increase in hospital profitability. CONCLUSION A major hospital commitment to Committee on Trauma verification had several salient outcomes; increased admissions, interfacility transfers, and acuity. Despite more seriously injured patients, there has been a major, sustained reduction in mortality and a trend toward decreased intensive care unit length of stay. This resulted in a substantial increase in contribution to margin (CTM), net profit, and revenues. With a high level of commitment and favorable payer mix, trauma center verification improves outcomes for both patients and the hospital.
Psychosocial, mental health, and behavioral issues of aging with HIV.

PURPOSE OF REVIEW People with HIV continue to live with the health consequences of an episodic illness that limits their ability to fully participate in society, particularly for the growing number of older people living with HIV. The present review describes the recent evidence exploring the psychosocial challenges facing older adults living with HIV. RECENT FINDINGS Aging for people with HIV may be more challenging than for the general population because of HIV-related stigma, loss of friends and social networks, and the detrimental effects that HIV and antiretroviral treatment have on normal aging processes. Older people with HIV are more likely to experience mental health and neurocognitive impairment than their HIV-negative counterparts, as well as more social isolation as a result of decreased social participation and engagement. People develop different approaches for coping with the challenges associated with aging with HIV. SUMMARY As this field of research evolves, many research gaps need to be addressed, including a better conceptualization and measurement of successful aging and the development of high-quality integrated care, programs, and services tailored to the needs of older people with HIV. A more integrated policy response is needed to improve the psychosocial and economic well being of older people with HIV.
Description Logic Modeling of Temporal Attribute-Based Access Control

In large-scale open systems like Internet, attribute based access control is more appropriate than some other access control mechanisms. A fragment of description logic can be used to represent and reason about policies of attribute-based access control, because with logic descriptions, policies have a clear syntax and semantics. Further more, with the description logic modeling, ABAC policies and subject attributes assertions are easy to be integrated with semantic Web language which is designed to facilitate the machine interpretability and interoperability in distributed environment. The description logic representation is flexible to hold broad scope of information about users and contexts. The temporal properties of access control are also specified in our model.
Role of the Renin-Angiotensin-Aldosterone System beyond Blood Pressure Regulation: Molecular and Cellular Mechanisms Involved in End-Organ Damage during Arterial Hypertension

Arterial hypertension is a common condition worldwide and an important predictor of several complicated diseases. Arterial hypertension can be triggered by many factors, including physiological, genetic, and lifestyle causes. Specifically, molecules of the renin-angiotensin-aldosterone system not only play important roles in the control of blood pressure, but they are also associated with the genesis of arterial hypertension, thus constituting a need for pharmacological interventions. Chronic high pressure generates mechanical damage along the vascular system, heart, and kidneys, which are the principal organs affected in this condition. In addition to mechanical stress, hypertension-induced oxidative stress, chronic inflammation, and the activation of reparative mechanisms lead to end-organ damage, mainly due to fibrosis. Clinical trials have demonstrated that renin-angiotensin-aldosterone system intervention in hypertensive patients lowers morbidity/mortality and inflammatory marker levels as compared to placebo patients, evidencing that this system controls more than blood pressure. This review emphasizes the detrimental effects that a renin-angiotensin-aldosterone system (RAAS) imbalance has on health considerations above and beyond high blood pressure, such as fibrotic end-organ damage.
When size matters: subshifts and their related tiling spaces

We investigate the dynamics of substitution subshifts and their associated tiling spaces. For a given subshift, the associated tiling spaces are all homeomorphic, but their dynamical properties may differ. We give criteria for such a tiling space to be weakly mixing, and for the dynamics of two such spaces to be topologically conjugate.
Robust Full Bayesian Learning for Neural Networks Draft of Cued/f-infeng/tr 343

In this paper, we propose a hierarchical full Bayesian model for neural networks. This model treats the model dimension (number of neurons), model parameters, regularisation parameters and noise parameters as random variables that need to be estimated. We develop a reversible jump Markov chain Monte Carlo (MCMC) method to perform the necessary computations. We nd that the results obtained using this method are not only better than the ones reported previously, but also appear to be robust with respect to the prior speci cation. In addition, we propose a novel and computationally e cient reversible jump MCMC simulated annealing algorithm to optimise neural networks. This algorithm enables us to maximise the joint posterior distribution of the network parameters and the number of basis function. It performs a global search in the joint space of the parameters and number of parameters, thereby surmounting the problem of local minima. We show that by calibrating the full hierarchical Bayesian prior, we can obtain the classical AIC, BIC and MDL model selection criteria within a penalised likelihood framework. Finally, we present a geometric convergence theorem for the algorithm with homogeneous transition kernel and a convergence theorem for the reversible jump MCMC simulated annealing method. i
Recurrence of focal segmental glomerulosclerosis after kidney transplantation: strategies and outcome

Purpose of reviewSteroid-resistant nephrotic syndrome/focal segmental glomerulonephritis (FSGS) is the primary renal disease in approximately 10% of pediatric patients receiving a renal allograft. Risk factors for recurrence are a chronological age between 6 and 15 years at onset of the nephrotic syndrome and a rapid progression of the disease in the native kidneys leading to end-stage renal disease in less than 3 years. With rapid recurrence of FSGS and loss of the allograft, further renal transplants also carry a high likelihood of recurrence of nephrotic syndrome. Recent findingsDifferent pathogenic factors have been discussed for the recurrence of proteinuria/FSGS in the transplanted kidney, especially the involvement of a proteinuric circulating factor. Treatment strategies are divided into two phases: induction of remission by plasma exchanges combined with high-dose intravenous or oral cyclosporine A; stabilization of remission by cyclophosphamide or rituximab, which showed promising results in several case reports. SummaryNo controlled studies have been performed yet to address the management of recurrent FSGS posttransplant. Complications related to the high-degree immunosuppression are not rare and should be regularly investigated. Therefore, the benefit: risk ratio for all immunosuppressive treatment strategies should be carefully evaluated for each individual patient.
A RTRM proposal for multi/many-core platforms and reconfigurable applications

Emerging multi/many-core architectures, targeting both High Performance Computing (HPC) and mobile devices, increase the interest for self-adaptive systems, where both applications and computational resources could smoothly adapt to the changing of the working conditions. In these scenarios, an efficient Run-Time Resource Manager (RTRM) framework can provide a valuable support to identify the optimal tradeoff between the Quality-of-Service (QoS) requirements of the applications and the time varying resources availability. This paper introduces a new approach to the development of a system-wide RTRM featuring: a) a hierarchical and distributed control, b) the exploitation of design-time information, c) a rich multi-objective optimization strategy and d) a portable and modular design based on a set of tunable policies. The framework is already available as an Open Source project, targeting a NUMA architecture and a new generation multi/many-core research platform. First tests show benefits for the execution of parallel applications, the scalability of the proposed multi-objective resources partitioning strategy, and the sustainability of the overheads introduced by the framework.
A Key Role for the α1 Helix of Human RAP74 in the Initiation and Elongation of RNA Chains*

RNA polymerase II-associating protein 74 (RAP74) is the large subunit of transcription factor IIF (TFIIF), which is essential for accurate initiation and stimulates elongation by RNA polymerase II. Mutations within or adjacent to the α1 helix of the RAP74 subunit have been shown to decrease both initiation and elongation stimulation activities without strongly affecting the interactions of RAP74 with the RAP30 subunit or the interaction between TFIIF and RNA polymerase II. In this manuscript, mutations within the α1 helix are compared with mutations made throughout the neighboring conserved N-terminal domain of RAP74. Changes within the N-terminal domain include disruptions of specific contacts with the α1 helix, which were revealed in the recently published x-ray crystal structure (Gaiser, F., Tan, S., and Richmond, T. J. (2000) J. Mol. Biol. 302, 1119–1127). Contacts between the β4-β5 loop and the α1 helix are shown to be largely unimportant for α1 helix function. Other mutations throughout the N-terminal domain are consistent with the establishment of the dimer interface with the RAP30 subunit. The RAP74-RAP30 interface is important for TFIIF function, but no particular RAP74 amino acids within this region have been identified that are required for TFIIF activities. The molecular target of the α1 helix remains unknown, but our studies refocus attention on this important functional motif of TFIIF.
A brief introduction to the military workplace culture.

BACKGROUND Military culture and workplace are areas of interest for researchers across disciplines. However, few publications on military culture exist. OBJECTIVE The purpose of this article is to introduce general concepts regarding the structure and culture of the United States Military and discuss how this creates challenges for reintegrating into the civilian world. METHOD Topics that will be covered in this article include an overview of the Department of Defense (DoD) and Department of Veterans Affairs (VA), socialization to military culture, the unique features of the military as a workplace, the cultural experiences of military personnel reintegrating back into the community, and the challenges faced by military members and their spouses. RESULTS The provided information on military culture will expand military cultural competency so that civilian employers can enhance their ability to create supportive workplaces for veterans and military spouses during times of transition and reintegration. DISCUSSION The unique characteristics of the military culture should be understood by those who work with or plan to work with military populations.
Locality and Availability in Distributed Storage

This paper studies the problem of information symbol availability in codes: we refer to a systematic code as code with (r, t)-availability if every information (systematic) symbol can be reconstructed from t disjoint groups of other code symbols, each of the sizes at most r. This paper shows that it is possible to construct codes that can support a scaling number of parallel reads while keeping the rate to be an arbitrarily high constant. It further shows that this is possible with the minimum Hamming distance arbitrarily close to the Singleton bound. This paper also presents a bound demonstrating a tradeoff between rate, minimum Hamming distance, and availability parameters. Our codes match the aforementioned bound, and their constructions rely on certain combinatorial structures. Resolvable designs provide one way to realize these required combinatorial structures. The two constructions presented in this paper require field sizes, which are linear and exponential in the code length, respectively. From a practical standpoint, our codes are relevant for distributed storage applications involving hot data, i.e., the information, which is frequently accessed by multiple processes in parallel.
Personality and hypnosis : a study of imaginative involvement

The best ebooks about Personality And Hypnosis A Study Of Imaginative Involvement that you can get for free here by download this Personality And Hypnosis A Study Of Imaginative Involvement and save to your desktop. This ebooks is under topic such as imaginative involvement and hypnotic susceptibility: a re hypnotic suggestibility and academic achievement: a role of fantasy proneness, imaginative involvement, and graham f wagstaff imagination and the hypnotic state minnesota symposia on child psychology imaginative involvement in antarctica: applications to abstracts from benjamin & susan gorsky: introduction to thomas w wall, phd, ps conversational assessment of hypnotic ability to promote hypnotic susceptibility related to an independent measure
The acceleration of OfSoftSwitch

The emerging trend of network devices with configurable data planes is pushing software switches as convenient playgrounds for experimenting novel programming paradigms and abstractions. OfSoftSwitch is a popular tool for carrying on such experimentation, as it provides a straightforward implementation of a pipeline of match-action tables. Unfortunately, OfSoftSwitch is not performance oriented and it is therefore limited only to functional experimentation of new abstractions. In this paper, we present our work to make OfSoftSwitch faster, while keeping it simple. The core of the work revolves around the use of the PFQ framework to expedite packet I/O operations as well as to enable multi-core parallel processing. In addition, other well-known techniques have also been applied to modify the original code of OfSoftSwitch. We demonstrate that our acceleration is effective by measuring a 96× performance speed-up, with more than 4 Mpps on a single core, when OfSoftSwitch performs OpenFlow forwarding. Likewise, we demonstrate that our approach is effective in keeping the simple programming model of OfSoftSwitch. In fact, we are able to effortlessly port OpenState, a stateful forwarding dataplane abstraction, to our accelerated OfSoftSwitch implementation.
Search-and-rescue dogs: an overview for veterinarians.

T use of dogs for search and rescue (SAR) was first recorded in the 1800s, but anecdotal evidence suggests that they may have been used 200 years earlier. Stories of heroic dogs during World War (WW) I and WWII represent some of the modern manifestations of organized SAR. These military dogs, known as ambulance and Red Cross dogs, were used on the battlefield to locate the wounded and deliver first aid supplies. Today, civilian SAR training conducted in the United States is largely based on methods used to train the military dogs in WWII. Since WWII, more than 150 SAR teams have been established in North America. Canine SAR teams in the United States are composed of specially trained search dogs and their human partners, who are often referred to as canine handlers. The handler commonly is also the owner, trainer, guardian, and companion of the SAR dog. Most canine SAR teams are composed of volunteers, and the dogs are personal pets as well as working partners. Depending on their specific training, teams are prepared to respond to crime scenes, accidents, missing person incidents, and natural and man-made disasters. The teams train and work in a wide variety of environments. Although most SAR dogs belong to working, herding, retrieving, or sporting breeds, dogs of numerous breeds, including mixed breeds, can be successful in SAR work. Important characteristics in a potential SAR dog are termed hunt drive, prey drive, and ball drive. A dog with high hunt drive will search for a hidden toy for prolonged periods without giving up or turning to the handler for assistance. A dog with high prey drive enjoys the chase and will enthusiastically pursue a person who runs away to hide or chase a toy that is dragged behind a handler. A dog with high ball drive is one in which a toy is extremely important, and the dog will play with and pursue the toy to the exclusion of any distractions. These qualities help predict the willingness and ability of a dog to search unendingly for a victim until he or she is found. Additionally, good candidates for SAR work are dogs that have good temperaments; rely on scent rather than visual contact for identifying prey; and are trainable, inquisitive, friendly, and need a purpose or focus for their energy. Dogs with high drive, which are desirable in SAR work, may not adjust well to a sedentary life style and therefore often are relinquished to animal shelters. Such dogs have the potential to be excellent SAR dogs.
Automatic selection of thresholds for signal separation algorithms based on interaural delay

In this paper we describe a system that separates signals by comparing the interaural time delays (ITDs) of their timefrequency components to a fixed threshold ITD. While in previous algorithms the fixed threshold ITD had been obtained empirically from training data in a specific environment, in real environments the characteristics that affect the optimal value of this threshold are unknown and possibly time varying. If these configurations are different from the environment under which the ITD threshold had been pre-computed, the performance of the source separation system is degraded. In this paper, we present an algorithm which chooses a threshold ITD that minimizes the cross-correlation of the target and interfering signals, after a compressive nonlinearity. We demonstrate that the algorithm described in this paper provides speech recognition accuracy that is much more robust to changes in environment than would be obtained using a fixed threshold ITD.
Do Only Economists Rely on Statistical Significance?

Economists, like other scientists, routinely rely on classical statistical inference to form expectations on whether a claim holds in academic research, with significance levels such as 0.05 being assigned special meaning. We present experimental evidence suggesting that most people are also belief conservative and that, if the degree of belief conservatism is restricted to a single value, the resulting hypothesis testing occurs using a 0.05 significance level for those subjects who are not best described by rational expectations.
Foundations of Exercise Psychology

Though exercise is relatively easy to do, its influence on our physical, psychological, and spiritual well-being is complex. Even those who are aware of its positive effects are sometimes reluctant to begin. Why do some people maintain a regular exercise regimen while others quit after a few weeks? How does exercise influence mental health? If medical, health, fitness, psychology, and athletic professionals are to help their clients, they must understand the issues that surround the psychology of exercise. 'Foundations of Exercise Psychology' presents a summary of the information to date on the psychology of exercise and offers lucid suggestions for practice and future research. 'Foundations of Exercise Psychology' will help to shape the direction of the field of exercise psychology for many years to come, and it will do much to encourage young professionals to enter the field and to pursue further study. Students moving toward the exercise professions will gain a solid background in key issues surrounding exercise and health and make great strides forward in becoming competent and compassionate practitioners. The contents of the book go well beyond past texts in the field and include some innovative and thought-provoking chapters on little discussed topics in exercise psychology such as the meaning of exercise and the psychological and physical dangers when exercise goes awry. The text spends considerable time exploring the relationship between exercise and personality, self-esteem, self-concept, mood alteration and motivation -- concepts and features of being human that are all intimately related. The range of populations examined includes women, children, dependent and habitual exercisers, and participants throughout the life span.
MtrR Modulates rpoH Expression and Levels of Antimicrobial Resistance in Neisseria gonorrhoeae

ABSTRACT The MtrR transcriptional-regulatory protein is known to repress transcription of the mtrCDE operon, which encodes a multidrug efflux pump possessed by Neisseria gonorrhoeae that is important in the ability of gonococci to resist certain hydrophobic antibiotics, detergents, dyes, and host-derived antimicrobials. In order to determine whether MtrR can exert regulatory action on other gonococcal genes, we performed a whole-genome microarray analysis using total RNA extracted from actively growing broth cultures of isogenic MtrR-positive and MtrR-negative gonococci. We determined that, at a minimum, 69 genes are directly or indirectly subject to MtrR control, with 47 being MtrR repressed and 22 being MtrR activated. rpoH, which encodes the general stress response sigma factor RpoH (sigma 32), was found by DNA-binding studies to be directly repressed by MtrR, as it was found to bind to a DNA sequence upstream of rpoH that included sites within the rpoH promoter. MtrR also repressed the expression of certain RpoH-regulated genes, but this regulation was likely indirect and a reflection of MtrR control of rpoH expression. Inducible expression of MtrR was found to repress rpoH expression and to increase gonococcal susceptibility to hydrogen peroxide (H2O2) and an antibiotic (erythromycin) recognized by the MtrC-MtrD-MtrE efflux pump system. We propose that, apart from its ability to control the expression of the mtrCDE-encoded efflux pump operon and, as a consequence, levels of gonococcal resistance to host antimicrobials (e.g., antimicrobial peptides) recognized by the efflux pump, the ability of MtrR to regulate the expression levels of rpoH and RpoH-regulated genes also modulates levels of gonococcal susceptibility to H2O2.