Miracle-dz/UniFAR-FTUs huggingface dataset:
BREEDING RESOURCE DISTRIBUTION AFFECTS SELECTION GRADIENTS ON MALE PHENOTYPIC TRAITS: EXPERIMENTAL STUDY ON LIFETIME REPRODUCTIVE SUCCESS IN THE BITTERLING FISH (RHODEUS AMARUS)

The spatial distribution of breeding resources can have pronounced demographic and evolutionary consequences. We used 20 experimental groups of the bitterling (Rhodeus amarus), an annual fish with a promiscuous, resource-based mating system, and extended breeding season to investigate how the spatial distribution (clumped or regular) of bitterling oviposition sites (live freshwater mussels) affected offspring production, variation in reproductive success, and directional selection on phenotypic traits over their entire reproductive lifetime. We did not detect any effect of resource distribution on offspring production or variation in reproductive success among individual fish, although variation between replicates was higher with a clumped distribution. This finding is discussed with regard to the incidence of alternative mating behaviors (sneaking) within the limitations imposed by our experimental design. Breeding resource distribution had a significant effect on selection on male phenotypic traits. Stronger directional selection on traits associated with intrasexual competition for fertilizations, gonad mass (an indicator of sperm competition), and the extent of red, carotenoid-based pigment in the iris (an index of dominance status), was detected with a clumped resource distribution. With a regular resource distribution, a stronger positive selection on male body size was detected. We discuss the implications of our results for natural populations.
Looking at the Schizophrenia Spectrum Through the Prism of Self-disorders: An Empirical Study

Nonpsychotic anomalies of subjective experience were emphasized in both classic literature and phenomenological psychiatry as essential clinical features of schizophrenia. However, only in recent years, their topicality with respect to the construct validity of the concept of the schizophrenia spectrum has been explicitly acknowledged, mainly as a consequence of the increasing focus on early detection and prevention of psychosis. The current study tested the hypothesis of a specific aggregation of self-disorders (SDs, various anomalies of self-awareness) in schizophrenia-spectrum conditions, comparing different diagnostic groups; 305 subjects, previously assessed in the Copenhagen Schizophrenia Linkage Study, were grouped into 4 experimental samples, according to their Diagnostic and Statistical Manual of Mental Disorders (Third Edition Revised) main diagnosis: schizophrenia, (n = 29), schizotypal personality disorder (n = 61), other mental illness not belonging to the schizophrenia spectrum (n = 112), and no mental illness (n = 103). The effect of diagnostic grouping on the level of SDs was explored via general linear model and logistic regression. The diagnosis of schizophrenia and schizotypy predicted higher levels of SDs, and SDs scores were significantly different between spectrum and nonspectrum samples; the likelihood of experiencing SDs increased as well with the diagnostic severity. The findings support the assumption that SDs are a discriminant psychopathological feature of the schizophrenia spectrum and suggest their incorporation to strengthen its construct validity, with potential benefit for both early detection and pathogenetic research.
Closed-loop precoding based on code distance allocation for spatial multiplexing systems

When MIMO channel information is available at the transmitter, closed-loop precoding can be introduced to improve system performance. In this paper, we proposed a novel closed-loop precoding algorithm based on code distance allocation for spatial multiplexing MIMO systems. We show that pairwise error probability of spatial multiplexing MIMO systems is determined by the minimum transmit code distance allocated to each eignmode subchannel. We give the structure of code distance allocation matrix to optimize transmit code distance. Our proposed structure of code distance allocation matrix can simultaneously optimize minimum code distance allocated to each subchannel. Computer simulations show that our proposed procoding algorithm can improve the performance of spatial multiplexing systems. Keywords-Spatial multiplexing; Beamforming; Precoding; Closed-loop; Code distance
Women’s autonomy and men's involvement in child care and feeding as predictors of infant and young child anthropometric indices in coffee farming households of Jimma Zone, South West of Ethiopia

Background Most of child mortality and under nutrition in developing world were attributed to suboptimal childcare and feeding, which needs detailed investigation beyond the proximal factors. This study was conducted with the aim of assessing associations of women’s autonomy and men’s involvement with child anthropometric indices in cash crop livelihood areas of South West Ethiopia. Methods Multi-stage stratified sampling was used to select 749 farming households living in three coffee producing sub-districts of Jimma zone, Ethiopia. Domains of women’s Autonomy were measured by a tool adapted from demographic health survey. A model for determination of paternal involvement in childcare was employed. Caring practices were assessed through the WHO Infant and young child feeding practice core indicators. Length and weight measurements were taken in duplicate using standard techniques. Data were analyzed using SPSS for windows version 21. A multivariable linear regression was used to predict weight for height Z-scores and length for age Z-scores after adjusting for various factors. Results The mean (sd) scores of weight for age (WAZ), height for age (HAZ), weight for height (WHZ) and BMI for age (BAZ) was -0.52(1.26), -0.73(1.43), -0.13(1.34) and -0.1(1.39) respectively. The results of multi variable linear regression analyses showed that WHZ scores of children of mothers who had autonomy of conducting big purchase were higher by 0.42 compared to children's whose mothers had not. In addition, a child whose father was involved in childcare and feeding had higher HAZ score by 0.1. Regarding age, as for every month increase in age of child, a 0.04 point decrease in HAZ score and a 0.01 point decrease in WHZ were noted. Similarly, a child living in food insecure households had lower HAZ score by 0.29 compared to child of food secured households. As family size increased by a person a WHZ score of a child is decreased by 0.08. WHZ and HAZ scores of male child was found lower by 0.25 and 0.38 respectively compared to a female child of same age. Conclusion Women’s autonomy and men’s involvement appeared in tandem with better child anthropometric outcomes. Nutrition interventions in such setting should integrate enhancing women’s autonomy over resource and men’s involvement in childcare and feeding, in addition to food security measures.
On the power of coercion abstraction

Erasable coercions in System F-eta, also known as retyping functions, are well-typed eta-expansions of the identity. They may change the type of terms without changing their behavior and can thus be erased before reduction. Coercions in F-eta can model subtyping of known types and some displacement of quantifiers, but not subtyping assumptions nor certain forms of delayed type instantiation. We generalize F-eta by allowing abstraction over retyping functions. We follow a general approach where computing with coercions can be seen as computing in the lambda-calculus but keeping track of which parts of terms are coercions. We obtain a language where coercions do not contribute to the reduction but may block it and are thus not erasable. We recover erasable coercions by choosing a weak reduction strategy and restricting coercion abstraction to value-forms or by restricting abstraction to coercions that are polymorphic in their domain or codomain. The latter variant subsumes F-eta, F-sub, and MLF in a unified framework.
Twisted connected sums and special Riemannian holonomy

We give a new, connected-sum-like construction of Riemannian metrics with special holonomy G_2 on compact 7-manifolds. The construction is based on a gluing theorem for appropriate elliptic partial differential equations. As a prerequisite, we also obtain asymptotically cylindrical Riemannian manifolds with holonomy SU(3) building up on the work of Tian and Yau. Examples of new topological types of compact 7-manifolds with holonomy G_2 are constructed using Fano 3-folds.
Partial evaluation in aircraft crew planning

In this paper we investigate how partial evaluation and program transformations can be used on a real problem, namely that of speeding up airline crew scheduling.Scheduling of crews is subject to many rules and restrictions. These restrictions are expressed in a rule language. However, in a given planning situation much is known to be fixed, so the rule set can be partially evaluated with respect to this known input.The approach is somewhat novel in that it uses truly static input data as well as static input data where the values are known only to belong to a set of values.The results of the partial evaluation is quite satisfactory: both compilation and running times have decreased by using it. The partial evaluator is now part of the crew scheduling system that Carmen Systems AB markets and which is in use at most of the major European airlines and in daily production.
Is the Medial Prefrontal Cortex Necessary for Theory of Mind?

Background Successful social interaction relies on the ability to attribute mental states to other people. Previous functional neuroimaging studies have shown that this process, described as Theory of Mind (ToM) or mentalization, is reliably associated with activation of the medial prefrontal cortex (mPFC). However, this study presents a novel and surprising finding that provides new insight into the role of the mPFC in mentalization tasks. Methodology/Principal Findings Twenty healthy individuals were recruited from a wide range of ages and social backgrounds. Participants underwent functional magnetic resonance imaging (fMRI) while viewing a well-established ToM visual paradigm involving moving triangles. Functional MRI data were analyzed using a classical general linear model. No activation was detected in the medial prefrontal cortex (mPFC) during movement patterns that typically elicit ToM. However, increased activity was observed in the right middle occipital gyrus, right temporoparietal junction (TPJ), left middle occipital gyrus and right inferior frontal gyrus. No correlation was found between participants’ age and BOLD response. Conclusions/Significance In contrast with previous neuroimaging research, our findings support the notion that mPFC function is not critical for reasoning about the mental states of others; furthermore, our data indicate that the right TPJ and right inferior frontal gyrus are able to perform mentalization without any contributions from the mPFC.
Blood concentrations of pimecrolimus in adult patients with atopic dermatitis following intermittent administration of pimecrolimus cream 1% (Elidel®) for up to 1 year

Objectives: To determine blood concentrations of pimecrolimus after long‐term intermittent administration of pimecrolimus cream 1% in adult patients with extensive atopic dermatitis (AD). Methods: This was an open‐label, multiple topical dose study in adults with moderate to severe AD and a total body surface area (TBSA) involvement of at least 20%. Pimecrolimus cream 1% was administered twice daily according to treatment need for up to 12 months to all lesions, including the neck and face. Blood samples were collected at regular timepoints and pimecrolimus concentrations were measured using a radioimmunoassay with a limit of quantitation (LoQ) of 0.5 ng/ml. Results: Forty patients (19 females), aged from 19 to 59 years, with moderate to severe AD entered the study. Twenty patients completed 6 months and 13 completed 1 year in the study. The individual blood concentrations of pimecrolimus were consistently low and there was no sign of drug accumulation. In 900 of the 918 samples examined (98%), pimecrolimus concentrations remained below the LoQ. The maximum concentration observed throughout the entire study was 0.8 ng/ml. Conclusion: Long‐term intermittent treatment of adult patients with extensive AD with pimecrolimus cream 1% is associated with minimal systemic exposure and no evidence of drug accumulation.
Topological Potential: Modeling Node Importance with Activity and Local Effect in Complex Networks

Modeling topological properties in the field of complex networks in recent years has been rather spectacular and amazing. A key question for characterizing topological structure is how to understand the importance of a node in network? Here we propose a topological potential model to obtain the global ranking which can reflect the importance of each node in given network. Through defining and calculating the topological potential score of each node, we modeled the node importance with activity and local effects. We find that the global ranking is a weak partial order ranked by a single measurement, the strict partial order of all nodes achieved by multi-measurements may be more reasonable. Furthermore we introduce equivalent class schema as a novel node importance evaluation strategy to obtain the ranking results under various measurements. Our experimental results demonstrated that the partial order ranking, as the form of top N is more essential to some real networks, compared with the results by the PageRank algorithms.
Effects of noise correlations on population coding

Neural responses show trial-to-trial variability (=noise) even if the same sensory stimulus is presented. Therefore the brain is considered to average and reduce the noises in order to obtain accurate sensory representations. However, Zohary et al. (1994) theoretically showed that the noises cannot be reduced when inter-neuronal correlations in noises, if any, exist in the simulation of a simple mathematical model. Here we analyze the effects of noise correlations on population coding in extended, but still simple, mathematical models.
Prevalence and determinants of contraceptive practice in a defined Nigerian population

This study investigates the prevalence and determinants of contraceptive practice in Ile-Ife, Nigeria. A prospective study of 500 rural women in the reproductive age group was conducted between April to June 1999 in the Igboya health district of Ife central local government area of Osun State. A comprehensive contraceptive promotion and distribution had been carried out in this area by the University Teaching Hospital, the State Ministry of Health and many non-governmental organisations in the past 10 years. It is therefore expected that the contraceptive awareness and use in this environment would be high. Unfortunately, although all the respondents (100%) were aware of contraception and 78% were sexually active, only 18·8% used contraception. A majority of the non-users gave no reasons for failure to use contraception. Among reasons given by others include fear of side effects, no need for contraception, not married, religion, need for more children and student status. The most common contraceptive method among users was intrauterine contraceptive device followed by pills, condoms and injectable contraceptives. Factors which were significantly associated with utilisation of contraception were availability of family planning services, parity, knowledge of contraception and child spacing ( P < 0·05). Religion, literacy level, attitudes of family planning providers and distance to family planning services were not found to be significant ( P > 0·05). Recommendations that will improve wide contraceptive usage are preferred.
An inadequate glycaemic response to glucagon is linked to insulin resistance in preterm infants?

Aims: To define clinical, metabolic, and hormonal characteristics of preterm infants relative to glucagon responsiveness. Methods: Two phase study of 78 preterm infants (25–36 weeks gestation) on regular four hourly feeds anticipating discharge home at 36 weeks mean corrected gestation. In phase 1 infants were fasted until hypoglycaemic, or maximally for eight hours. Endocrine and metabolic profiles were obtained at completion. Phase 2 was performed the following day. A feed was omitted and replaced by a bolus dose of intravenous glucagon (100 μg/kg). Main outcome measures were measurements of blood glucose and lactate concentrations, taken immediately pre-glucagon, and thereafter every 15 minutes for 60 minutes. A rise in glucose concentration of >1 mmol/l (55 infants) was defined as an adequate response to glucagon. An inadequate glycaemic response was <1 mmol/l (23 infants). Results: Several differences in fasting blood glucose and hormone concentrations were identified in infants with an inadequate glycaemic response to glucagon compared to those with an adequate response: relative fasting hyperglycaemia (mean 3.7 v 3.3 mmol/l, p = 0.008); fasting hyperinsulinaemia (mean 4.3 v 2.6 mU/l, p = 0.014); an increased insulin:glucagon ratio (0.19 v 0.11, p = 0.014), and a lower insulin sensitivity QUICKI index (0.19 v 0.22, p = 0.04). There was no distinctive phenotype to reliably predict response to glucagon. Conclusion: Some preterm infants show an inadequate glycaemic response to glucagon and have features suggestive of insulin resistance. The potential long term implications of such insulin resistance may have appreciable public health consequences.
FINAL STATE INTERACTIONS IN ε ′ /ε a

Strong final state interaction (FSI) effects can play a central role in the Standard Model prediction of weak K → 2π matrix elements. Here, I discuss how FSI's affect the direct CP violation parameter ε ′ /ε by solving the Omnès problem for the necessary K → 2π amplitudes. The main results of this analysis have been reported in a previous paper 1 and are further discussed in Refs. 2,3. The resulting Standard Model prediction Re(ε ′ /ε) = (15 ± 5) × 10 −4 is in good agreement with the present experimental world average.
Life satisfaction and general life experience in judo and other sport coaches.

Abstract The goal of our study was find the differences between judo coaches and coaches in other sports, in the dimensions of life satisfaction and general life experience, as well as according to the demographic variables and in variables directly linked with a coaching. We have examined a total of 132 coaches of various sports in Croatia (43 judo coaches and the rest were from other sports) during the seminar for coaches in Croatian Olympic Academy. For measuring satisfaction with life, we used Extended Satisfaction With Life Scale (modification of Pavot’s & Diener’s (1993) Satisfaction With Life Scale) and the Questionnaire about General Life Experience (Andrijasevi c , 2009). Judo coaches showed higher education level, more medals achieved on national championships, more memberships in cadet and junior national team, comparing with the coaches from other sports. They are older, more work experienced in general as well as a coach, longer active in a top sport, later ended their professional carrier. In life satisfaction and general life experience, judo coaches have higher life achievement, lower daily fatigue but higher level of negative emotions and stress.
An AR system for haptic communication

Touch is an important part of human communication. Through handshakes, hugs and a myriad of personal gestures, we convey our emotions and express our feelings. However, how such interactions can be achieved over distance remains a relatively unexplored area of research. To begin to rectify this we present the description of a system that enables one user to reach out and touch another distant user and for both to feel the resultant physical contact. In this initial exploration, we focus on the practical feasibility of this idea, and describe the technical components required.
Aviation Remaining Seats Marketing Decision Support System Based on Revenue Management

The paper gives a definition about the remaining seats and constructs the framework of a revenue management and designs a revenue management decision support system for aviation remaining seats. Because of the characteristics of remaining seats, the paper considers the factors of marketing environment and combines the idea of marketing management with principles of revenue management. At last, an aviation remaining seats marketing decision support system is designed.
Walking and dementia in physically capable elderly men.

CONTEXT Evidence suggests that physical activity may be related to the clinical expression of dementia. Whether the association includes low-intensity activity such as walking is not known. OBJECTIVE To examine the association between walking and future risk of dementia in older men. DESIGN Prospective cohort study. SETTING AND PARTICIPANTS Distance walked per day was assessed from 1991 to 1993 in 2257 physically capable men aged 71 to 93 years in the Honolulu-Asia Aging Study. Follow-up for incident dementia was based on neurological assessment at 2 repeat examinations (1994-1996 and 1997-1999). MAIN OUTCOME MEASURES Overall dementia, Alzheimer disease, and vascular dementia. RESULTS During the course of follow-up, 158 cases of dementia were identified (15.6/1000 person-years). After adjusting for age, men who walked the least (<0.25 mile/d) experienced a 1.8-fold excess risk of dementia compared with those who walked more than 2 mile/d (17.8 vs 10.3/1000 person-years; relative hazard [RH], 1.77; 95% confidence interval [CI], 1.04-3.01). Compared with men who walked the most (>2 mile/d), an excess risk of dementia was also observed in those who walked 0.25 to 1 mile/d (17.6 vs 10.3/1000 person-years; RH, 1.71; 95% CI, 1.02-2.86). These associations persisted after accounting for other factors, including the possibility that limited amounts of walking could be the result of a decline in physical function due to preclinical dementia. CONCLUSIONS Findings suggest that walking is associated with a reduced risk of dementia. Promoting active lifestyles in physically capable men could help late-life cognitive function.
Fyn tyrosine kinase is a downstream mediator of Rho/PRK2 function in keratinocyte cell–cell adhesion

The Rho GTPase and Fyn tyrosine kinase have been implicated previously in positive control of keratinocyte cell–cell adhesion. Here, we show that Rho and Fyn operate along the same signaling pathway. Endogenous Rho activity increases in differentiating keratinocytes and is required for both Fyn kinase activation and increased tyrosine phosphorylation of β- and γ-catenin, which is associated with the establishment of keratinocyte cell–cell adhesion. Conversely, expression of constitutive active Rho is sufficient to promote cell–cell adhesion through a tyrosine kinase- and Fyn-dependent mechanism, trigger Fyn kinase activation, and induce tyrosine phosphorylation of β- and γ-catenin and p120ctn. The positive effects of activated Rho on cell–cell adhesion are not induced by an activated Rho mutant with defective binding to the serine/threonine PRK2/PKN kinases. Endogenous PRK2 kinase activity increases with keratinocyte differentiation, and, like activated Rho, increased PRK2 activity promotes keratinocyte cell–cell adhesion and induces tyrosine phosphorylation of β- and γ-catenin and Fyn kinase activation. Thus, these findings reveal a novel role of Fyn as a downstream mediator of Rho in control of keratinocyte cell–cell adhesion and implicate the PRK2 kinase, a direct Rho effector, as a link between Rho and Fyn activation.