Miracle-dz/UniFAR-FTUs huggingface dataset:
Compact Rx/Tx Channel Duplexer with Tuning Capability for Integration in a 26GHz High Capacity Short Haul Radio Equipment

A novel Ka-band Rx/Tx channel duplexer1 design with tuning capability is established for the 26GHz band. Thus, only a single hardware is necessary to serve all duplex channel combinations of the overall radio frequency band - a prerequisite for large scale low cost unit production. The applied filters consider optimal tailored transfer functions with transmission zeros, realized with compact planar overmoded TE103 cavity structures to accommodate the extreme rejection demands while maintaining low insertion loss. A further design aspect has been easy integration and interfacing into the waveguide subsystem of the radio equipment. The complete duplexer structure has been designed using a mode matching based CAD. To satisfy the stability of the responses for the given outdoor environmental conditions it has been realized from silverplated INVAR sheets - a technique supporting the low cost issue. Good agreement of computed and measured results and the successful testing of the tuning capability verifies the design.
In Vivo Immunostaining of Hemocyte Compartments in Drosophila for Live Imaging

In recent years, Drosophila melanogaster has become an attractive model organism in which to study the structure and development of the cellular immune components. The emergence of immunological markers greatly accelerated the identification of the immune cells (hemocytes), while the creation of genetic reporter constructs allowed unique insight into the structural organization of hematopoietic tissues. However, investigation of the hemocyte compartments by the means of immunological markers requires dissection and fixation, which regularly disrupt the delicate structure and hamper the microanatomical characterization. Moreover, the investigation of transgenic reporters alone can be misleading as their expression often differs from the native expression pattern of their respective genes. We describe here a method that combines the reporter constructs and the immunological tools in live imaging, thereby allowing use of the array of available immunological markers while retaining the structural integrity of the hematopoietic compartments. The procedure allows the reversible immobilization of Drosophila larvae for high-resolution confocal imaging and the time-lapse video analysis of in vivo reporters. When combined with our antibody injection-based in situ immunostaining assay, the resulting double labeling of the hemocyte compartments can provide new information on the microanatomy and functional properties of the hematopoietic tissues in an intact state. Although this method was developed to study the immune system of Drosophila melanogaster, we anticipate that such a combination of genetic and immunological markers could become a versatile technique for in vivo studies in other biological systems too.
Phylogeography and pigment type diversity of Synechococcus cyanobacteria in surface waters of the northwestern pacific ocean

The widespread unicellular cyanobacteria Synechococcus are major contributors to global marine primary production. Here, we report their abundance, phylogenetic diversity (as assessed using the RNA polymerase gamma subunit gene rpoC1) and pigment diversity (as indirectly assessed using the laterally transferred cpeBA genes, encoding phycoerythrin-I) in surface waters of the northwestern Pacific Ocean, sampled over nine distinct cruises (2008-2015). Abundance of Synechococcus was low in the subarctic ocean and South China Sea, intermediate in the western subtropical Pacific Ocean, and the highest in the Japan and East China seas. Clades I and II were by far the most abundant Synechococcus lineages, the former dominating in temperate cold waters and the latter in (sub)tropical waters. Clades III and VI were also fairly abundant in warm waters, but with a narrower distribution than clade II. One type of chromatic acclimater (3dA) largely dominated the Synechococcus communities in the subarctic ocean, while another (3dB) and/or cells with a fixed high phycourobilin to phycoerythrobilin ratio (pigment type 3c) predominated at mid and low latitudes. Altogether, our results suggest that the variety of pigment content found in most Synechococcus clades considerably extends the niches that they can colonize and therefore the whole genus habitat.
Moving Research into Practice: Can We Make Dissemination Stick?

Although researchers in special education have made significant advances in defining and identifying evidence-based practices, scholars often constitute an insular group that disseminates research findings primarily through outlets and venues targeting like-minded researchers using traditional approaches. Thus, despite tangible results in determining what works, using dissemination approaches that fail to resonate with or influence practitioners represents an important but often overlooked contributor to the ongoing research-to-practice gap in special education. The authors argue that empirical and theoretical literature outside of special education may offer insight into how ideas take hold, which may be especially relevant to the effective dissemination of evidence-based practices. Drawing on Heath and Heath's (2008) model, the authors describe 6 characteristics of messages that are likely to “stick”: (a) simple, (b) unexpected, (c) concrete, (d) credible, (e) emotional, and (f) stories. The authors consider each in terms of implications for dissemination of special education research findings, and urge special education researchers to consider researching, refining, and applying dissemination strategies that can make special education research matter on a broader scale.
Individual Characteristics and Social Knowledge in Ethical Reasoning

Individual differences and structures of social knowledge in ethical reasoning were examined with 234 graduate business school students to see, among other things, what would be the role of gender in ethical reasoning. Individuals bring a variety of psychological, philosophical, and ethical orientations to organizational life, challenging traditional managerial assumptions concerning appropriate responses to ethical dilemmas. Using quantitative and qualitative methods, this research demonstrated that the individual characteristics of gender, learning style, and personality characteristics are significantly more influential in the use of an ethic of care or an ethic of justice in ethical reasoning than are the structures of social knowledge. In this study, social knowledge was measured through the preference for an organic or mechanistic world view and a communitarian or consequentialist moral orientation.
Further characterization of malignant glioma-derived vascular permeability factor.

The nature of vascular permeability factor (VPF) activity derived from serum-free conditioned medium containing cultured human malignant glial tumors has been further investigated. A 1000-fold purification was accomplished by sequential heparin-Sepharose affinity chromatography and high-performance liquid chromatography gel filtration chromatography steps. Vascular permeability factor activity falls into a molecular weight range of 41,000 to 56,000 D. Activity is bound to hydroxylapatite, carboxymethyl-Sepharose, phenyl-Sepharose, and heparin-Sepharose, whereas little or no activity was bound to diethylaminoethyl-Sephacel. Vascular permeability factor activity is trypsin- and pepsin-sensitive but is unaffected by treatment with ribonuclease A. This suggests that VPF is a hydrophobic, positively charged (cationic) polypeptide with a potentially biologically significant affinity for heparin. As most proteins are negatively charged (anionic) and have no affinity for heparin, a significant advantage was gained by performing these purification steps. The activity of VPF is not inhibited by coinjection of conditioned medium with soybean trypsin inhibitor; or hexadimethrine (both known antagonists of tissue plasminogen activator, Hageman factor, and serum kallikrein); or aprotinin (an antagonist of both plasmin and tissue kallikrein); or phenylmethanesulfonyl fluoride (a serine esterase (elastase) inhibitor); or pepstatin-A (an acid protease inhibitor which inactivates vascular permeability-inducing leukokinins). These data, together with the fact that VPF is produced and released into serum-free media, provides substantial evidence against it being one of the more commonly known serum-derived permeability mediators. Treatment with dithiothreitol inhibited VPF activity, indicating the presence of at least one essential disulfide bond in this molecule. Inhibition by dexamethasone of VPF expression in cultured malignant glial cells appears to be selective. Dexamethasone-induced inhibition of VPF was dose-responsive and was not associated with a parallel inhibition of cellular protein synthesis as determined by tritiated leucine incorporation into trichloroacetic acid-precipitable material. Inclusion of dexamethasone in the culture medium was not associated with altered cell viability or cell number. A series of in vivo studies confirmed the inhibition of VPF activity in test animals pretreated with dexamethasone. This steroid-induced inhibition was partially reversed by treatment of test animals with actinomycin D prior to exposure to dexamethasone. (ABSTRACT TRUNCATED AT 400 WORDS)
Statistical maps for EEG dipolar source localization

We present a method that estimates three-dimensional statistical maps for electroencephalogram (EEG) source localization. The maps assess the likelihood that a point in the brain contains a dipolar source, under the hypothesis of one, two or three activated sources. This is achieved by examining all combinations of one to three dipoles on a coarse grid and attributing to each combination a score based on an F statistic. The probability density function of the statistic under the null hypothesis is estimated nonparametrically, using bootstrap resampling. A theoretical F distribution is then fitted to the empirical distribution in order to allow correction for multiple comparisons. The maps allow for the systematic exploration of the solution space for dipolar sources. They permit to test whether the data support a given solution. They do not rely on the assumption of uncorrelated source time courses. They can be compared to other statistical parametric maps such as those used in functional magnetic resonance imaging (fMRI). Results are presented for both simulated and real data. The maps were compared with LORETA and MUSIC results. For the real data consisting of an average of epileptic spikes, we observed good agreement between the EEG statistical maps, intracranial EEG recordings, and fMRI activations.
Acoustic Monitoring and Localization for Social Care

Increase in the number of older people due to demographic changes poses great challenges to the social healthcare systems both in the Western and as well as in the Eastern countries. Support for older people by formal care givers leads to enormous temporal and personal efforts. Therefore, one of the most important goals is to increase the efficiency and effectiveness of today’s care. This can be achieved by the use of assistive technologies. These technologies are able to increase the safety of patients or to reduce the time needed for tasks that do not relate to direct interaction between the care giver and the patient. Motivated by this goal, this contribution focuses on applications of acoustic technologies to support users and care givers in ambient assisted living (AAL) scenarios. Acoustic sensors are small, unobtrusive and can be added to already existing care or living environments easily. The information gathered by the acoustic sensors can be analyzed to calculate the position of the user by localization and the context by detection and classification of acoustic events in the captured acoustic signal. By doing this, possibly dangerous situations like falls, screams or an increased amount of coughs can be detected and appropriate actions can be initialized by an intelligent autonomous system for the acoustic monitoring of older persons. The proposed system is able to reduce the false alarm rate compared to other existing and commercially available approaches that basically rely only on the acoustic level. This is due to the fact that it explicitly distinguishes between the various acoustic events and provides information on the type of emergency that has taken place. Furthermore, the position of the acoustic event can be determined as contextual information by the system that uses only the acoustic signal. By this, the position of the user is known even if she or he does not wear a localization device such as a radio-frequency identification (RFID) tag. Category: Smart and intelligent computing
More than "Model Minorities" or "Delinquents": A Look at Hmong American High School Students

Hmong American youth are often stereotyped by the popular press as either high-achieving "model minorities" or low-achieving "delinquents. " In this ethnographic study, Stacey Lee attempts to move beyond the model minority image of 1.5-generation students and the delinquent stereotype of second-generation students to present a more complex picture of Hmong American students' school experiences. The author explores the way economic forces, relationships with the dominant society, perceptions of opportunities, family relationships, culture, and educational experiences affect Hmong American students' attitudes toward school, and the variation that exists among 1.5- and second-generation youth. This article provides insight into how forces inside and outside school affect attitudes toward education, and suggests possibilities for ways in which schools might better serve these students. (pp. 505–528)
Separation-individuation, vulnerability to stress and psychological symptoms in late adolescents.

SEPARATION-INDIVIDUATION, VULNERABILITY TO STRESS AND PSYCHOLOGICAL SYMPTOMS IN LATE ADOLESCENTS FEBRUARY 1992 AUDREY ELLEN TOLMAN, B.A., HARVARD UNIVERSITY M.S., UNIVERSITY OF MASSACHUSETTS Directed by: Professor Susan K. Whitbourne Psychoanalytic and family systems theorists recognize that psychological separation from the family of origin is a primary task of late adolescence, and the successful completion of this task is considered by many to be a prerequisite for healthy adjustment. This study examines the relationship between dimensions of psychological separation from parents and the experience of stress in late adolescent college students. It was hypothesized that several different dimensions of dependence on parents would be associated with academic, family and social stress and that family stress in particular would be a strong predictor of psychological symptoms. The roles played by self-esteem and coping in the prediction of symptoms were explored, as were possible gender and age differences in dependence, stress and symptoms. Differences according to parents' marital status were also assessed. Two hundred and thirty-nine male and female undergraduates participated in the study by completing a series of questionnaires including the Psychological Separation Inventory, the College Adjustment Rating Scale, the Ways of Coping Checklist-Revised, and the Symptom Checklist-90-Revised. The results indicate that conflictual dependence on one or both parents is associated with stress in all three domains and is most strongly associated with family stress. Family stress emerged as an important predictor of symptoms for females only;
Approaches to Capture Variance Differences in Rest fMRI Networks in the Spatial Geometric Features: Application to Schizophrenia

Identification of functionally connected regions while at rest has been at the forefront of research focusing on understanding interactions between different brain regions. Studies have utilized a variety of approaches including seed based as well as data-driven approaches to identifying such networks. Most such techniques involve differentiating groups based on group mean measures. There has been little work focused on differences in spatial characteristics of resting fMRI data. We present a method to identify between group differences in the variability in the cluster characteristics of network regions within components estimated via independent vector analysis (IVA). IVA is a blind source separation approach shown to perform well in capturing individual subject variability within a group model. We evaluate performance of the approach using simulations and then apply to a relatively large schizophrenia data set (82 schizophrenia patients and 89 healthy controls). We postulate, that group differences in the intra-network distributional characteristics of resting state network voxel intensities might indirectly capture important distinctions between the brain function of healthy and clinical populations. Results demonstrate that specific areas of the brain, superior, and middle temporal gyrus that are involved in language and recognition of emotions, show greater component level variance in amplitude weights for schizophrenia patients than healthy controls. Statistically significant correlation between component level spatial variance and component volume was observed in 19 of the 27 non-artifactual components implying an evident relationship between the two parameters. Additionally, the greater spread in the distance of the cluster peak of a component from the centroid in schizophrenia patients compared to healthy controls was observed for seven components. These results indicate that there is hidden potential in exploring variance and possibly higher-order measures in resting state networks to better understand diseases such as schizophrenia. It furthers comprehension of how spatial characteristics can highlight previously unexplored differences between populations such as schizophrenia patients and healthy controls.
Genome‐scale techniques highlight the epigenome and redefine fundamental principles of gene regulation

The regulation of gene expression represents one of the most fundamental of biologic processes that controls cellular proliferation, differentiation, and function. Recent technological advances in genome‐wide annotation together with bioinformatic/computational analyses have contributed significantly to our understanding of transcriptional regulation at the epigenomic and regulomic levels. This perspective outlines the techniques that are being utilized and summarizes a few of the outcomes. © 2011 American Society for Bone and Mineral Research.
Conversational Exploratory Search via Interactive Storytelling

Conversational interfaces are likely to become more efficient, intuitive and engaging way for human-computer interaction than today's text or touch-based interfaces. Current research efforts concerning conversational interfaces focus primarily on question answering functionality, thereby neglecting support for search activities beyond targeted information lookup. Users engage in exploratory search when they are unfamiliar with the domain of their goal, unsure about the ways to achieve their goals, or unsure about their goals in the first place. Exploratory search is often supported by approaches from information visualization. However, such approaches cannot be directly translated to the setting of conversational search. In this paper we investigate the affordances of interactive storytelling as a tool to enable exploratory search within the framework of a conversational interface. Interactive storytelling provides a way to navigate a document collection in the pace and order a user prefers. In our vision, interactive storytelling is to be coupled with a dialogue-based system that provides verbal explanations and responsive design. We discuss challenges and sketch the research agenda required to put this vision into life.
Designing more effective on‐campus teaching and learning spaces: a role for academic developers

Teaching and learning on campus takes place within specific physical settings that are integral to the process. The traditional, teacher‐centred and didactic instruction of universities has been embedded in the constructed environment of the campus, particularly the lecture theatres and other formal classrooms. However, these same facilities now threaten to impede the implementation of more student‐centred and flexible learning approaches being introduced in higher education worldwide. Recent attempts to create new teaching and learning facilities on university campuses have often resulted in celebrated architecture that has proved to be educationally problematic. What types of physical settings are required to support the teaching and learning processes emerging in higher education? This paper draws on the author's work in the field, and argues that academic developers have a key role to play in assisting universities to engage effectively in the design and development of more effective teaching and lear.
Can Gamification Motivate Voluntary Contributions?: The Case of StackOverflow Q&A Community

Online communities heavily rely on voluntary participation and continued engagement from users because these sites can flourish only if there are meaningful contributions from community members. Gamifying the underlying incentive mechanism can be a solution to elicit and sustain the desired user behavior. In this paper, we develop a theory of gamification and study the impact of a hierarchical badges system, a reward mechanism based on gamification principles, on user participation and engagement at Stack Overflow Q&A site. Specifically, we assess the extent to which users are incentivized by earned badges in their contributions to the answering activity. Our initial results present strong empirical evidence that confirms the value of the badges and the effectiveness of gamification in stimulating voluntary participation.
Expression of Multiple Na+/H+ Exchanger Isoforms in Cultured Epithelial Cells from Rat Efferent Duct and Cauda Epididymidis1

Abstract Although earlier work has pointed to the presence of Na+/H+ exchangers (NHEs) in the rat epididymis, little is known about the regional distribution of various NHE isoforms and their functions. In the present work, expression of different isoforms of NHE in cultured epithelia of the efferent duct and cauda epdidymidis were studied. Reverse transcription-polymerase chain reaction revealed the presence of NHE1, NHE2, and NHE3, but not NHE4, message in both cultured epithelia. Western blot analysis detected the presence of NHE1 and NHE2 proteins in both cultured epithelia, but NHE3 protein was only detected in the cultured epithelial cells from the efferent duct. Immunohistochemical studies demonstrated that NHE2 was localized in the cytoplasm of the ciliated cells, whereas NHE3 was localized at the apical membrane of the principal cells of the efferent duct. The NHE activities in both cultured epithelia were inhibited by 10 μM HOE-694 (3-methylsulphonyl-4-piperidinobenzoyl guanidine methanesulphonate), a NHE1 inhibitor, by approximately 76%. The HOE-694-resistant NHE activities in the cultured epithelia of efferent duct and cauda epididymidis were completely inhibited by 20 μM S3226 (3-[2-(3-guanidino-2-methyl-3-oxo-propenyl)-5-methyl-phenyl]-N-isopropylidene-2-methyl-acrylamide dihydrochloride), a NHE3 inhibitor, and 300 μM HOE-694 (a dose that can completely block NHE2), respectively. These results indicated that NHE1, NHE2, and NHE3 were expressed in the cultured epithelial cells of the efferent duct, whereas only NHE1 and NHE2 were expressed in the cultured epithelial cells of the cauda epididymidis. It is suggested that NHE1 may provide “housekeeping” functions in both epithelia, whereas NHE2 in the cauda epididymidis and NHE3 in the efferent duct may be involved in Na+ reabsorption and regulation of pH of the luminal fluid.