Miracle-dz/UniFAR-FTUs huggingface dataset:
Phytochemical Profile and Biological Activities of Helianthemum canum l. baumg. from Turkey

In the current study, antioxidant, antibacterial activities, and the phenolic compositions of extracts from Helianthemum canum L. Baumg. (Apiaceae) aerial parts were investigated for the first time. The H. canum was extracted with 70% methanol (HCMeOH) and water (HCW). Both extracts were determined by total phenolic contents (3 mg/ml), flavonoids (1.5 mg/ml), flavonols (1.5 mg/ml), qualitative–quantitative compositions, iron (II) chelation activities (0.1 – 5 mg/ml), free radical scavenging activities (DPPH•: 0.01 – 0.6 mg/ml and ABTS+•: 0.125 – 0.5 mg/ml) and the effect upon inhibition of β‐carotene/linoleic acid co‐oxidation (1 mg/ml). The peroxidation level was also determined using the thiobarbituric acid method (0.01 – 1.5 mg/ml). The results of the activity tests given as IC50 values were estimated from non‐linear algorithm and compared with standards. Antibacterial activities of extracts and standards were evaluated against Gram‐negative and ‐positive ten standard strains using disc diffusion and broth microdilution methods. The MIC results (312.5 – 2500 μg/ml) against tested microorganisms varied from 625 to 2500 μg/ml. In HPLC analysis, 3,5‐dihydroxybenzoic acid was found as the main substance in both extracts. These results showed that HCMeOH was richer in phenolic compounds (284.13 ± 0.30 mg GAE/g extract) from HCW (244.55 ± 0.35 mg GAE/g extract). In conclusion, H. canum extracts showed in vitro antibacterial and antioxidant activities.
Evaluation of the gastrointestinal tract in patients with iron-deficiency anemia.

BACKGROUND Idiopathic iron-deficiency anemia in adults is assumed to be the result of occult chronic blood loss from the gastrointestinal tract. The aim of this study was to determine an effective clinical strategy for managing this common clinical problem. BACKGROUND We prospectively studied 100 consecutive patients with iron-deficiency anemia, using colonoscopy and esophagogastroduodenoscopy and, in patients with negative endoscopic studies, enteroclysis (radio-graphic examination of the small intestine). RESULTS Gastrointestinal endoscopy revealed at least one lesion potentially responsible for blood loss in 62 of the 100 patients. Endoscopic examination of the upper gastrointestinal tract showed a bleeding source in 36 patients, and colonoscopy showed a lesion in 25; 1 patient had lesions in both the upper and lower gastrointestinal tracts. The most common abnormality in the upper gastrointestinal tract was peptic ulceration (duodenal ulcer in 11 patients, gastric ulcer in 5, and anastomotic ulcer in 3). Cancers, detected in 11 patients, were the most common colonic lesions. Enteroclysis was performed in 26 of the 38 patients with negative endoscopic studies, and the results were normal in all instances. Symptoms at a specific site in the gastrointestinal tract were predictive of disease in the corresponding portion of the bowel. In addition, the combination of positive tests for fecal occult blood and symptoms in the lower gastrointestinal tract had a positive predictive value of 86 percent for detecting a lesion in the lower gastrointestinal tract. CONCLUSIONS Gastrointestinal lesions (in both the upper gastrointestinal tract and the colon) are frequently found in patients with iron-deficiency anemia. Since site-specific symptoms are predictive of abnormalities in the corresponding portion of the bowel, the initial evaluation should be directed by the location of the symptoms. Concomitant lesions of the upper and lower gastrointestinal tract are rare; thus, detection of a likely source of blood loss during the initial examination may obviate the need for further procedures.
Simple Interpolated FFT Algorithm Based on Minimize Sidelobe Windows for Power-Harmonic Analysis

This paper focuses on the low-computation harmonic-analysis procedure with sufficient suppression of spectral leakage and picket-fence effect. The interpolated FFT algorithm based on the minimized sidelobe window is considered, and its calculate procedure and formulas are given, which is free of solving high-order equations. The implementation of the proposed algorithm in the digital-signal-processor (DSP) based three-phase harmonic ammeter is also introduced. The proposed algorithm has the major advantages that the calculate formulas for harmonic parameters can be easily implemented by hardware multipliers, making the method a good choice for real-time applications. The simulation and application results validate the accuracy and efficiency of the proposed algorithm.
Human performance using computer input devices in the preferred and non-preferred hands

Subjects' performance was compared in pointing and dragging tasks using the preferred and non-preferred hands. Tasks were tested using three different input devices: a mouse, a trackball, and a tablet-with-stylus. The trackball had the least degradation across hands in performing the tasks, however it remained inferior to both the mouse and stylus. For small distances and small targets, the preferred hand was superior. However, for larger targets and larger distances, both hands performed about the same. The experiment shows that the non-preferred hand is more than a poor approximation of the preferred hand. The hands are complementary, each having its own strength and weakness. One design implication is that the non-preferred hand is well suited for tasks that do not require precise action, such as scrolling.
Diverging Opinions

We commonly observe cases where two people who see the same evidence draw opposite conclusions, and that additional information seems only to polarize them further. One view of this is that it demonstrates failure of Bayesian reasoning, or the need for non-common priors. By contrast, we explain the phenomenon using a Bayesian model with common priors. We assume a model with two-dimensional uncertainty in which there is no prior disagreement about an true state. Nevertheless, a disagreement among agents may arise and continually increase if additional information becomes available on only one of the states. We provide support for our model by testing it experimentally. Furthermore, in the lab, the disagreement tends to increase more for the subjects whose behavior is more consistent with Bayesian behavior.
Co-occurrence Patterns of Some Small-bodied Freshwater Fishes in Southwestern France: Implications for Fish Conservation and Environmental Management

Abstract We assessed the influence of environmental variables (elevation, stream order, distance from source, catchment area, slope, stream width, and fish species richness) on the co-occurrence patterns of the minnow, the stone loach, and the gudgeon at the stream system scale. A total of 474 sites were classified according to the seven variables using the Self-Organizing Map (neural network), and three clusters were detected (k-means algorithm). The frequency of the various fish co-occurrence patterns was calculated for each cluster, and general linear modeling was used to specify the conditions that predict the occurrence of each species. Piedmont streams were more likely to support coexisting gudgeon and minnow populations because of higher probabilities of occurrence for both species. The higher co-occurrence frequency for the three species together in headwater streams resulted from lower occurrence frequencies in gudgeon and minnow. Focusing on areas that favor the co-occurrence of species may enhance the effectiveness of conservation projects.
Comparative study of the ion flux pathway in stator units of proton- and sodium-driven flagellar motors

Flagellar motor proteins, MotA/B and PomA/B, are essential for the motility of Escherichia coli and Vibrio alginolyticus, respectively. Those complexes work as a H+ and a Na+ channel, respectively and play important roles in torque generation as the stators of the flagellar motors. Although Asp32 of MotB and Asp24 of PomB are believed to function as ion binding site(s), the ion flux pathway from the periplasm to the cytoplasm is still unclear. Conserved residues, Ala39 of MotB and Cys31 of PomB, are located on the same sides as Asp32 of MotB and Asp24 of PomB, respectively, in a helical wheel diagram. In this study, a series of mutations were introduced into the Ala39 residue of MotB and the Cys31 residue of PomB. The motility of mutant cells were markedly decreased as the volume of the side chain increased. The loss of function due to the MotB(A39V) and PomB(L28A/C31A) mutations was suppressed by mutations of MotA(M206S) and PomA(L183F), respectively, and the increase in the volume caused by the MotB(A39V) mutation was close to the decrease in the volume caused by the MotA(M206S) mutation. These results demonstrate that Ala39 of MotB and Cys31 of PomB form part of the ion flux pathway and pore with Met206 of MotA and Leu183 of PomA in the MotA/B and PomA/B stator units, respectively.
Decentralized Precoding Algorithm with Weighted SLNR for Limitedly Coordinated Network

We propose a decentralized precoding algorithm for multicell network with limited coordination. The decentralized precoding algorithm controls interference effectively without user data sharing between base stations. Since the signal-to-leakage-plus-noise-ratio (SLNR) maximization algorithm does not guarantee a weak user's performance, we maximize the weighted SLNR by giving a weight factor to the weak user based on the channel quality information parameter. Simulation results show that the adoption of weight factors improves performance of the weak user such that the fairness among users is guaranteed.
Total body water in malnourished infants.

Total body water has been studied in 24 malnourished infants by the method of isotope dilution, using tritium administered parenterally as tritiated water: urinary activity has been measured in a gas flow counter designed for accurate measurement of low energy radiation. The results show: 1. A great increase in proportion of water in the malnourished child as compared with normal: average 84.5 percent of body weight on admission and 62.6 percent on recovery (the normal TBW percent body weight varies slightly with age but is approximately 60 percent). 2. A gross depletion of body solids. On admission the average body solids were only 29 percent (range 11-70 percent) of normal for age. The results were consistent with nitrogen balance data (AU)
Trends in bovine abortions submitted to the Ontario Ministry of Agriculture, Food and Rural Affairs, 1993-1995.

Based on data from April 1994 to March 1995 at the Veterinary Laboratory Services Branch, Ontario Ministry of Agriculture, Food and Rural Affairs (VLSB, OMAFRA), the rate of cattle herds with abortion was 0.24, or about 1 out of every 4 herds. This estimate was obtained by dividing the number (504) of herds with diagnoses of abortion (based on pathology) by the number (2105) of herds submitting material for pathologic diagnosis to VLSB laboratories in Brighton, Guelph, Kemptville, and Ridgetown. The data likely represent the proportion of herds with serious abortion problems. Other research has estimated the number of herds in Ontario with any aborted calves at about twice the VLSB rate (1).
Effect of Aspirin and Saiicylate on Platelet‐Vessel Wall Interactions in Rabbits

We performed studies to examine the mechanism responsible for the antithrombogenic effect of aspirin in experimental animals. We measured the effect of 10 and 100 mg/kg doses of aspirin, saiicylate, or a combination of both on the accumulation of radiolabeled platelets onto injured carotid arteries in rabbits. The effects of these agents on thrombogenecity measured as platelet accumulation onto injured carotid arteries, were correlated with the ability to inhibit platelet thromboxane A2 and vessel wall prostacyclin synthesis. We found that a low dose of aspirin significantly inhibited platelet accumulation onto the injured vessels, while a high dose reversed this effect. Thromboxane A2 and prostacyclin production, however, were maximally inhibited in rabbits given either aspirin dose. The reversal of the antithrombotic effect of the low dose of aspirin by a high dose of aspirin was simulated by administering a combination dose of high-dose saiicylate and low-dose aspirin. We concluded that the reversal of the antithrombotic effect of a 10 mg/kg dose of aspirin by a higher dose of aspirin could not be explained solely by the inhibition of PGI2 synthesis and was affected by the saiicylate moiety of aspirin.
Photoreceptor dystrophy in the RCS rat: roles of oxygen, debris, and bFGF.

PURPOSE To examine the roles of oxygen, basic fibroblast growth factor (bFGF), and photoreceptor debris in the photoreceptor dystrophy of the Royal College of Surgeons (RCS) rat. METHODS Pups were exposed during the critical period of their development (postnatal day [P] 16-24) and for some days thereafter to hypoxia and hyperoxia. The effects of these exposures on photoreceptor death, debris accumulation in the subretinal space, and the expression of bFGF protein and mRNA by surviving cells were studied. RESULTS During the critical period hyperoxia slowed photoreceptor death in a dose-related fashion and decreased bFGF protein levels, whereas hypoxia accelerated death and increased bFGF levels. At the edges of the retina, where photoreceptors survive longest in normoxia, hypoxia had little effect on either photoreceptor death or bFGF protein levels. Oxygen-induced modulation of rates of death could not be related to the accumulation of debris in the subretinal space. After P27, the relationship between oxygen and photoreceptor death changed markedly, hyperoxia no longer delaying and hypoxia no longer accelerating death. CONCLUSIONS The death of RCS rat photoreceptors in the period P16 to P27 is precipitated by hypoxia that may result from the accumulation of photoreceptor debris in the subretinal space. This debris, the result of the phagocytotic failure of the retinal pigment epithelium in this strain, lies in the normal pathway of oxygen diffusing to the photoreceptors from the choriocapillaris. During this period the retina responds to hypoxia by increasing expression of a potentially protective protein (bFGF), but hypoxia-induced damage overwhelms any protection provided by this or other mechanisms. Later stages of the dystrophy may not be hypoxia-induced.
The relationship between cerebral oxygen saturation changes and postoperative cognitive dysfunction in elderly patients after coronary artery bypass graft surgery.

OBJECTIVE The aim of this study was to evaluate the predictive value of cerebral regional oxygen saturation (rSO(2)) in the occurrence of postoperative cognitive dysfunction (POCD) in elderly patients undergoing coronary artery bypass graft (CABG) surgery. DESIGN A prospective study. SETTING University hospital. PARTICIPANTS A total of 61 patients (84% male) with a mean age of 70.39 ± 4.69 on a waiting list for CABG surgery were enrolled in the study. INTERVENTION A complete neurocognitive evaluation was performed 1 day before surgery as well as 4 to 7 days and 1 month after surgery. During surgery, rSO(2) was monitored continuously. MEASUREMENTS AND MAIN RESULTS POCD was defined as a reduction of 1 standard deviation on 2 or more neuropsychologic indices. Forty-six patients (80.7%) developed early POCD, and 23 (38.3%) showed late POCD. Patients whose rSO(2) decreased to less than 50% during the surgery experienced more POCD 4 to 7 days after surgery (p = 0.04). In addition, a decrease of more than 30% from the patient's baseline rSO(2) was associated with POCD 1 month after surgery (p = 0.03). CONCLUSION Intraoperative cerebral oxygen desaturation is associated with early and late POCD in elderly patients. Cerebral oximetry is a promising tool in the prediction of subtle neuropsychologic deficits and further studies are needed.
Volume analysis of heat-induced cracks in human molars: A preliminary study

Context: Only a few methods have been published dealing with the visualization of heat-induced cracks inside bones and teeth. Aims: As a novel approach this study used nondestructive X-ray microtomography (micro-CT) for volume analysis of heat-induced cracks to observe the reaction of human molars to various levels of thermal stress. Materials and Methods: Eighteen clinically extracted third molars were rehydrated and burned under controlled temperatures (400, 650, and 800°C) using an electric furnace adjusted with a 25°C increase/min. The subsequent high-resolution scans (voxel-size 17.7 μm) were made with a compact micro-CT scanner (SkyScan 1174). In total, 14 scans were automatically segmented with Definiens XD Developer 1.2 and three-dimensional (3D) models were computed with Visage Imaging Amira 5.2. 2. The results of the automated segmentation were analyzed with an analysis of variance (ANOVA) and uncorrected post hoc least significant difference (LSD) tests using Statistical Package for Social Sciences (SPSS) 17. A probability level of P < 0.05 was used as an index of statistical significance. Results: A temperature-dependent increase of heat-induced cracks was observed between the three temperature groups (P < 0.05, ANOVA post hoc LSD). In addition, the distributions and shape of the heat-induced changes could be classified using the computed 3D models. Conclusion: The macroscopic heat-induced changes observed in this preliminary study correspond with previous observations of unrestored human teeth, yet the current observations also take into account the entire microscopic 3D expansions of heat-induced cracks within the dental hard tissues. Using the same experimental conditions proposed in the literature, this study confirms previous results, adds new observations, and offers new perspectives in the investigation of forensic evidence.
Neuroscientific Model of Motivational Process

Considering the neuroscientific findings on reward, learning, value, decision-making, and cognitive control, motivation can be parsed into three sub processes, a process of generating motivation, a process of maintaining motivation, and a process of regulating motivation. I propose a tentative neuroscientific model of motivational processes which consists of three distinct but continuous sub processes, namely reward-driven approach, value-based decision-making, and goal-directed control. Reward-driven approach is the process in which motivation is generated by reward anticipation and selective approach behaviors toward reward. This process recruits the ventral striatum (reward area) in which basic stimulus-action association is formed, and is classified as an automatic motivation to which relatively less attention is assigned. By contrast, value-based decision-making is the process of evaluating various outcomes of actions, learning through positive prediction error, and calculating the value continuously. The striatum and the orbitofrontal cortex (valuation area) play crucial roles in sustaining motivation. Lastly, the goal-directed control is the process of regulating motivation through cognitive control to achieve goals. This consciously controlled motivation is associated with higher-level cognitive functions such as planning, retaining the goal, monitoring the performance, and regulating action. The anterior cingulate cortex (attention area) and the dorsolateral prefrontal cortex (cognitive control area) are the main neural circuits related to regulation of motivation. These three sub processes interact with each other by sending reward prediction error signals through dopaminergic pathway from the striatum and to the prefrontal cortex. The neuroscientific model of motivational process suggests several educational implications with regard to the generation, maintenance, and regulation of motivation to learn in the learning environment.
Fabrication of Large Mechanically Flexible Multi-Layered PDMS Optical Devices

Mechanically flexible large area polydimethylsiloxane (PDMS) optical devices are fabricated using soft-lithography techniques based on replica moulding. These non-rigid optical devices can be designed as sheets to act as either light concentrators (collectors) or diffusers (illuminators) based on the position and geometry of micro-optical structures (MOSs) embedded within the sheet or imprinted on its surface. The active surface area of the device can range from less than a sq. cm to several sq. m. The performance of the large area optical device is a function of the location and geometry of micro-optical structures, thickness and shape of the flexible waveguide, core and cladding material (ie. refractive indices), and the wavelength of the incident light source. A centrifugal casting technique that simultaneously de-gasses and fills a patterned, thin mould cavity is introduced as the backbone to the proposed fabrication methodology. Combined with the ability to control the refractive index of PDMS and a partial curing technique that bonds subsequent layers, a bottom-up layer-by-layer fabrication process is proposed and described in detail.
Study and Design of New Reactive Routing Protocol Advance AODV for Mobile Ad hoc Networks

A mobile ad-hoc network is a collection of mobile nodes forming an ad-hoc network without the assistance of any centralized structures. These networks shows a new way of network establishment and these are well suited for an environment where either the infrastructure is lost or where deploy an infrastructure is not very cost effective. We have presented the overview of Ad hoc network routing protocols. In this paper we worked to solve the problem of intermediate route building in Ad hoc on demand distance vector routing protocol (AODV) and proposed scheme that enhances the performance of AODV protocol. The scheme proposed by us is AdvanceAd hoc on demand distance vector (AAODV) routing protocol. It consists of the use of Ad-hoc On demand Distance Vector with Backup routing (AODV-BR) and concept of local recovery with limited TTL value in case of failure of local recovery in first attempt i.e. if the neighboring node of the node that find the link break do not have path to destination in its alternate routing table.
Tablets quickly disintegrating in the oral cavity and process for producing the same

Tablets quickly disintegrating in the oral cavity which contain a drug, a diluent and a saccharide having a melting point lower than the melting points of the drug and the diluent, wherein the low-melting saccharide is uniformly dispersed in the tablets and crosslinkage of the low-melting saccharide, which has been once molten and solidified, is formed among particles of the drug and/or the diluent. Compared with the conventional tablets quickly disintegrating in the oral cavity, the above tablets have an enhanced tablet strength and an improved abrasion resistance without prolonging the disintegration time in the oral cavity.