Miracle-dz/UniFAR-FTUs huggingface dataset:
CORE AND CYLINDER STRENGTHS OF NATURAL AND LIGHTWEIGHT CONCRETE

THE COMPRESSIVE STRENGTH OF LABORATORY CURED AND FIELD CURED CYLINDERS ARE COMPARED WITH 4 AND 6 IN. DIAMETER CORES AT AGES UP TO 84 DAYS. NEARLY 500 SAMPLES OF NATURAL AND LIGHTWEIGHT CONCRETE UNDER SIMULATED JOB CONDITIONS SHOWED THAT ALL CORES AT COMPARABLE AGES TESTED LOWER THAN CYLINDERS. /AUTHOR/
The impact of childhood sexual abuse on the outcome of intensive trauma-focused treatment for PTSD

ABSTRACT Background: It is assumed that PTSD patients with a history of childhood sexual abuse benefit less from trauma-focused treatment than those without such a history. Objective: To test whether the presence of a history of childhood sexual abuse has a negative effect on the outcome of intensive trauma-focused PTSD treatment. Method: PTSD patients, 83% of whom suffered from severe PTSD, took part in a therapy programme consisting of 2 × 4 consecutive days of Prolonged Exposure (PE) and EMDR therapy (eight of each). In between sessions, patients participated in sport activities and psycho-education sessions. No prior stabilization phase was implemented. PTSD symptom scores of clinician-administered and self-administered measures were analysed using the data of 165 consecutive patients. Pre-post differences were compared between four trauma groups; patients with a history of childhood sexual abuse before age 12 (CSA), adolescent sexual abuse (ASA; i.e. sexual abuse between 12 and 18 years of age), sexual abuse (SA) at age 18 and over, or no history of sexual abuse (NSA). Results: Large effect sizes were achieved for PTSD symptom reduction for all trauma groups (Cohen’s d = 1.52–2.09). For the Clinical Administered PTSD Scale (CAPS) and the Impact of Event Scale (IES), no differences in treatment outcome were found between the trauma (age) groups. For the PTSD Symptom Scale Self Report (PSS-SR), there were no differences except for one small effect between CSA and NSA. Conclusions: The results do not support the hypothesis that the presence of a history of childhood sexual abuse has a detrimental impact on the outcome of first-line (intensive) trauma-focused treatments for PTSD.
Overt Weight Stigma, Psychological Distress and Weight Loss Treatment Outcomes

Weight stigma is pervasive and is associated with psychosocial distress. Little research has examined the association between weight stigma and weight loss treatment outcomes. The current investigation examined overt weight stigma, depression, binge eating, and weight loss treatment outcomes in a sample of 55 overweight and obese adults. Overt weight stigma was significantly associated with greater depression and binge eating and poorer weight loss treatment outcomes in a 14-week behavioral weight loss program, suggesting that overt weight stigma may be detrimental to overweight and obese individuals’ ability to lose weight and engage in behaviors consistent with weight loss.
Fine needle aspiration biopsy of solitary fibrous tumor of the pleura. A report of two cases with a discussion of diagnostic pitfalls.

BACKGROUND The diagnosis of a peripheral pulmonary nodule presents a challenge due to many diagnostic possibilities and pitfalls. We describe the cytologic features of solitary fibrous tumor of the pleura, differential diagnoses, pertinent immunohistochemical stains and histogenesis. CASES Two cases of solitary fibrous tumor of the pleura showed two cell populations on cytologic preparations; mesothelial cells and spindle cells. The neoplastic spindle cell component was positive for CD-34 and vimentin but not for cytokeratin. CONCLUSION Solitary fibrous tumor of the pleura is rare but should be included in the differential diagnosis of a peripheral pulmonary nodule. Fine needle aspiration biopsy is a safe and rapid method of providing a confirmatory diagnosis.
Reduced Self-Control after 3 Months of Imprisonment; A Pilot Study

Background: Prison can be characterized as an impoverished environment encouraging a sedentary lifestyle with limited autonomy and social interaction, which may negatively affect self-control and executive function. Here, we aim to study the effects of imprisonment on self-control and executive functions, and we report the change in neuropsychological outcome after 3 months of imprisonment. Materials and Methods: Participants were 37 male inmates in a remand prison in Amsterdam, Netherlands, who completed six tests of a computerized neuropsychological test battery (the Cambridge Automated Neuropsychological Test Battery) in the first week of arrival. Participants were retested after 3 months of imprisonment. Change in performance was tested using the Wilcoxon Signed-Rank test. Results: After 3 months of imprisonment, risk taking significantly increased (measured as an increase in the proportion of available points used for betting) and attention significantly deteriorated (measured as increased variability in reaction times on a sustained attention task), with large to medium effect sizes. In contrast, planning significantly improved (measured with a task analog to the Tower of London) with a medium effect size. Discussion: Our study suggests that 3 months of imprisonment in an impoverished environment may lead to reduced self-control, measured as increased risk taking and reduced attentional performance. This is a significant and societally relevant finding, as released prisoners may be less capable of living a lawful life than they were prior to their imprisonment, and may be more prone to impulsive risk-taking behavior. In other words, the impoverished environment may contribute to an enhanced risk of reoffending.
Compiling Diderot: From Tensor Calculus to C

Diderot is a parallel domain-specific language for analysis and visualization of multidimensional scientific images, such as those produced by CT and MRI scanners. In particular, it supports algorithms where tensor fields (i.e., functions from 3D points to tensor values) are used to represent the underlying physical objects that were scanned by the imaging device. Diderot supports higher-order programming where tensor fields are first-class values and where differential operators and lifted linear-algebra operators can be used to express mathematical reasoning directly in the language. While such lifted field operations are central to the definition and computation of many scientific visualization algorithms, to date they have required extensive manual derivations and laborious implementation. The challenge for the Diderot compiler is to effectively translate the high-level mathematical concepts that are expressible in the surface language to a low-level and efficient implementation in C. This paper describes our approach to this challenge, which is based around the careful design of an intermediate representation (IR), called EIN, and a number of compiler transformations that lower the program from tensor calculus to C while avoiding combinatorial explosion in the size of the IR. We describe the challenges in compiling a language like Diderot, the design of EIN, and the transformation used by the compiler. We also present an evaluation of EIN with respect to both compiler efficiency and quality of generated code.
Measurement on Pyrolytic Active Materials of Bagasse Biomass by Py-GC-MS

In order to find out its active materials, the extractives of bagasse biomass were adsorbed and determined by Py-GC-MS. And the main constituents were 1-phenanthrenecarboxylic acid, 1,2,3,4,4a,9,10,10a- octahydro-1,4a-di methyl-7-(1-methylethyl)-( 24.24%), nonadecane, 1-chloro-(4.36%), stigmast-4-en-3-one(3.94%), 1-nonadecene(3.84%), etc.
Fine needle aspiration cytology in the management of male breast masses. Nineteen years of experience.

OBJECTIVE To determine the utility and accuracy of fine needle aspiration cytology (FNAC) as well as its sensitivity, specificity and predictive value in the diagnosis of male breast masses. STUDY DESIGN Data on male breast FNAC done between 1978 and 1997 were retrieved from the records of the cytopathology laboratory. FNAC diagnoses were categorized as positive, negative, inconclusive or unsatisfactory. Cytohistologic correlation was done with data from histopathology records. Sensitivity, specificity, diagnostic accuracy and predictive values of FNAC were calculated using standard statistical methods. RESULTS Five hundred seven of 13,175 patients undergoing breast FNAC were males. Of them, 393/507 had satisfactory aspirates. Of these, 70 were positive (13.8%), 295 were negative (58%), and 29 were inconclusive (5.7%). A total of 114 FNACs (22.5%) were unsatisfactory. Histopathology was available in 97/507 cases. There were no false positive or false negative diagnoses. FNAC had a sensitivity, specificity and diagnostic accuracy of 100% for male breast lesions. CONCLUSION This large study shows that FNAC is a very accurate tool for diagnosis of male breast lesions. It is highly sensitive and specific, with good cytohistologic correlation. FNAC should therefore be an integral part of the primary assessment of breast lumps in males.
Joint rank and positive semidefinite constrained optimization for projection matrix

Sparse signals can be sensed with a reduced number of projections and then reconstructed if compressive sensing is employed. Traditionally, the projection matrix is chosen as a random matrix, but a projection sensing matrix that is optimally designed for a certain class of signals can further improve the reconstruction accuracy. This paper considers the problem of designing the projection matrix Φ for a compressive sensing system in which the dictionary Ψ is assumed to be given. A novel algorithm based on joint rank and positive semidefinite constrained optimization for optimal projection matrix searching is proposed. Simulation results reveal that the signal recovery performance of sensing matrix obtained by proposed algorithm surpasses that of other standard sensing matrix designs.
Measuring E-mail header injections on the world wide web

E-mail header injection vulnerability is a class of vulnerability that can occur in web applications that use user input to construct e-mail messages. E-mail header injection vulnerabilities exist in the built-in e-mail functionality of the popular languages PHP, Java, Python, and Ruby. With the proper injection string, this vulnerability can be exploited to allow an attacker to inject additional headers, modify existing headers, and alter the content of the e-mail. While E-mail header injection vulnerabilities are known to the community, and some commercial vulnerability scanners claim to discover E-mail header injection vulnerabilities, they have never been studied by the academic community. This paper presents a scalable mechanism to automatically detect E-mail header injection vulnerabilities and uses this mechanism to quantify the prevalence of E-mail header injection vulnerabilities on the web. From crawling 23,553,796 URLs, we found 994 vulnerable URLs across 414 domains. 135 of these domains are in the Alexa top 1 million, and five of them are in the top 20,000. 137 of the vulnerable domains are using anti-spoofing mechanisms such as DKIM, SPF, or DMARC, and E-mail header injection renders this protection useless. This work shows that E-mail header injection vulnerabilities are widespread and deserve future research attention.
Semantic interoperability in global information systems

Internet, Web and distributed computing infrastructures continue to gain in popularity as a means of communication for organizations, groups and individuals alike. In such an environment, characterized by large distributed, autonomous, diverse, and dynamic information sources, access to relevant and accurate information is becoming increasingly complex. This complexity is exacerbated by the evolving system, semantic and structural heterogeneity of these potentially global, cross-disciplinary, multicultural and rich-media technologies. Clearly, solutions to these challenges require addressing directly a variety of interoperability issues.
Safety and efficacy of ruxolitinib in myelofibrosis patients without splenomegaly

bosis. Haematologica, 100, e226–e228. Roques, M. , Park, J.-H. , Minello, A. , Bastie, J.N. & Girodon, F. (2015) Detection of the CALR mutation in the diagnosis of splanchnic vein thrombosis. British Journal of Haematology, 169, 601–603. Sekhar, M. , McVinnie, K. & Burroughs, A.K. (2013) Splanchnic vein thrombosis in myeloproliferative neoplasms. British Journal of Haematology, 162, 730–747. Smalberg, J., Arends, L.R. , Valla, D.C., Kiladjian, J.J., Janssen, H. & Leebeek, F.W. G. (2012) Myeloproliferative neoplasms in Budd-Chiari syndrome and portal vein thrombosis: a metaanalysis. Blood, 120, 4921–4928. Turon, F. , Cervantes, F. , Colomer, D. , Baiges, A. , Hern andez-Gea, V. & Garcia Pagan, J.C. (2015) Role of calreticulin mutations in the etiological diagnosis of splanchnic vein thrombosis. Journal of Hepatology, 2015, 72–74.
Tactual sensitivity in hypochondriasis.

BACKGROUND In his article on amplification, somatization and somatoform disorders Barsky [Psychosomatics 1992; 33:28-34] pointed out the importance of studying the perception and processing of somatic and visceral symptoms. Subsequently, it was demonstrated that hypochondriacal patients are not more accurately aware of cardiac activity than a group of non-hypochondriacal patients. Authors concluded that hypochondriacal somatic complaints do not result from an unusually fine discriminative ability to detect normal physiological sensations that non-hypochondriacal patients are unable to perceive. The aim of the present study was to investigate tactual sensitivity to non-painful stimuli in hypochondriacal patients and healthy subjects. METHODS Twenty-seven outpatients with DSM-III-R hypochondriasis and 27 healthy control subjects were compared. In all subjects the two-point discrimination threshold was measured, as well as subjective sensitivity to harmless bodily sensations as measured by the Somatosensory Amplification Scale. RESULTS It was found that hypochondriacal patients reported more distress and discomfort with benign bodily sensations. The two-point discrimination threshold of hypochondriacal patients was not significantly lower in patients as compared to controls. CONCLUSIONS Hypochondriacal subjects considered themselves more sensitive to benign bodily sensations without being better able to discriminate between two tactual bodily signals. These findings of the present study correspond quite closely to those reported earlier.
Runx2‐I is an Early Regulator of Epithelial–Mesenchymal Cell Transition in the Chick Embryo

Background: Although normally linked to bone and cartilage development, the Runt‐related transcription factor, RUNX2, was reported in the mouse heart during development of the valves. We examined RUNX2 expression and function in the developing avian heart as it related to the epithelial–mesenchymal transition (EMT) in the atrioventricular canal. EMT can be separated into an activation stage involving hypertrophy and cell separation and an invasion stage where cells invade the extracellular matrix. The localization and activity of RUNX2 was explored in relation to these steps in the heart. As RUNX2 was also reported in cancer tissues, we examined its expression in the progression of esophageal cancer in staged tissues. Results: A specific isoform, RUNX2‐I, is present and required for EMT by endothelia of the atrioventricular canal. Knockdown of RUNX2‐I inhibits the cell–cell separation that is characteristic of initial activation of EMT. Loss of RUNX2‐I altered expression of EMT markers to a greater extent during activation than during subsequent cell invasion. Transforming growth factor beta 2 (TGFβ2) mediates activation during cardiac endothelial EMT. Consistent with a role in activation, RUNX2‐I is regulated by TGFβ2 and its activity is independent of similarly expressed Snai2 in regulation of EMT. Examination of RUNX2 expression in esophageal cancer showed its upregulation concomitant with the development of dysplasia and continued expression in adenocarcinoma. Conclusions: These data introduce the RUNX2‐I isoform as a critical early transcription factor mediating EMT in the developing heart after induction by TGFβ2. Its expression in tumor tissue suggests a similar role for RUNX2 in the EMT of metastasis. Developmental Dynamics 247:542–554, 2018. © 2017 Wiley Periodicals, Inc.
Performance of an Imaging System vs. Manual Screening in the Detection of Squamous Intraepithelial Lesions of the Uterine Cervix

OBJECTIVE To compare the ThinPrep Imaging System (Cytyc Corp., Boxborough Massachusetts, U.S.A) to manual screening in the detection of cervical squamous epithelial lesion (SIL). STUDY DESIGN A total of 27,525 manually screened ThinPrep Pap tests were compared with 27,725 imaged ThinPrep Pap tests for: (1) diagnostic rates of atypical squamous cells of undetermined significance; atypical squamous cells of undetermined significance, cannot rule out high grade SIL (ASC-H); low grade SIL and high grade SIL (HSIL); (2) ASC/SIL ratio; (3) high-risk HPV positivity for ASC; and (4) biopsy follow-up for ASC-H and HSIL. RESULTS There were significant increases in the percentage of cytologic diagnoses in all categories with the imager. The ASC/SIL ratios of both groups were comparable. There was a significant decrease in HPV positivity in the imager group of ASC. Biopsy results confirmed a significant increase in the detection of HSIL in both the ASC-H and HSIL groups of the imaged cohort. CONCLUSION The ThinPrep Imaging System is significantly better than manual screening in the detection of cervical SIL.
Effect of Cu infiltration on static and dynamic properties of PM steels

Performance improvement that can be achieved by Cu infiltration is quantified in this paper. Tensile and fatigue properties of a Fe–2·0Cu–0·7C powder metallurgy steel were compared to the same alloy infiltrated with 8 wt-%Cu. Microstructural characterisation, using optical and electron microscopies, was carried out to understand the effect of Cu infiltration on mechanical properties. Cu infiltration improves the ultimate tensile strength by 40% by increasing the load bearing structure, decreasing the stress concentrations associated to open porosity and increasing the hardness of the steel matrix. Fractographic observations show the evidence of stress transmission from the sinternecks to the steel particles due to infiltrated Cu. The beneficial effect of Cu infiltration is less pronounced for the fatigue properties as the endurance limit is increased by 10%. This lower improvement is explained by crack initiating at the Cu/steel matrix interface.
An Oligodendrocyte Cell Adhesion Molecule at the Site of Assembly of the Paranodal Axo-Glial Junction

Two major isoforms of the cell adhesion molecule neurofascin NF186 and NF155 are expressed in the central nervous system (CNS). We have investigated their roles in the assembly of the node of Ranvier and show that they are targeted to distinct domains at the node. At the onset of myelination, NF186 is restricted to neurons, whereas NF155 localizes to oligodendrocytes, the myelin-forming glia of the CNS. Coincident with axon ensheathment, NF155 clusters at the paranodal regions of the myelin sheath where it localizes in apposition to the axonal adhesion molecule paranodin/contactin-associated protein (Caspr1), which is a constituent of the septate junction-like axo-glial adhesion zone. Immunoelectron microscopy confirmed that neurofascin is a glial component of the paranodal axo-glial junction. Concentration of NF155 with Caspr1 at the paranodal junctions of peripheral nerves is also a feature of Schwann cells. In Shiverer mutant mice, which assemble neither compact CNS myelin nor normal paranodes, NF155 (though largely retained at the cell body) is also distributed at ectopic sites along axons, where it colocalizes with Caspr1. Hence, NF155 is the first glial cell adhesion molecule to be identified in the paranodal axo-glial junction, where it likely interacts with axonal proteins in close association with Caspr1.
The impact of different seats and whole-body vibration exposures on truck driver vigilance and discomfort

Abstract Laboratory studies have shown that exposure to whole-body vibration (WBV) increases physical and mental fatigue, which are common issues professional drivers face. The objective of this study was to determine whether altering WBV exposures had any effect on driver vigilance and discomfort. A repeated measures crossover design of five truck drivers with regular 10-h routes was used. Active and passive suspension truck seats were evaluated. For each seat, WBV exposures were measured. Participants completed a discomfort questionnaire and a reaction time task before and after their shift for two weeks, one week per seat. Compared with the passive seat, the active seat significantly reduced WBV exposures, decrements in the optimal and mean reaction times (p = 0.02, 0.047, respectively), and discomfort in the lower back and wrist(s)/forearm(s) (p < 0.01, 0.01, respectively). Study results indicated that reducing WBV helps reduce discomfort and maintain vigilance, which may improve drivers’ health and reduce the risk of truck collisions. Practitioner Summary: The active suspension seat used in this study reduced truck drivers’ exposure to whole-body vibration (WBV) by over 33% in relation to their current industry standard passive suspension seat. This study demonstrated that reducing truck drivers’ exposure to WBV reduced fatigue and discomfort development over a workday.
RANKL inhibition through osteoprotegerin blocks bone loss in experimental periodontitis.

BACKGROUND Prevention of alveolar bone destruction is a clinical challenge in periodontal disease treatment. The receptor activator of nuclear factor-kappa B ligand (RANKL) inhibitor osteoprotegerin (OPG) inhibits osteoclastogenesis and suppresses bone resorption. METHODS To study the effects of RANKL inhibition on alveolar bone loss, an experimental ligature-induced model of periodontitis was used. A total of 32 rats were administered human OPG-Fc fusion protein (10 mg/kg) or vehicle by subcutaneous delivery twice weekly for 6 weeks. Negative or positive controls received no treatment or disease through vehicle delivery, respectively. Biopsies were harvested after 3 and 6 weeks, and mandibulae were evaluated by microcomputed tomography (microCT) and histology. Serum levels of human OPG-Fc and tartrate-resistant acid phosphatase-5b (TRAP-5b) were measured throughout the study by enzyme-linked immunosorbent assay (ELISA). Statistical analyses included analysis of variance (ANOVA) and Tukey tests. RESULTS Human OPG-Fc was detected in the sera of OPG-Fc-treated animals by 3 days and throughout the study. Serum TRAP-5b was sharply decreased by OPG-Fc treatment soon after OPG-Fc delivery and remained low for the observation period. Significant preservation of alveolar bone volume was observed among OPG-Fc-treated animals compared to the controls at weeks 3 and 6 (P <0.05). Descriptive histology revealed that OPG-Fc significantly suppressed osteoclast surface area at the alveolar crest. CONCLUSION Systemic delivery of OPG-Fc inhibits alveolar bone resorption in experimental periodontitis, suggesting that RANKL inhibition may represent an important therapeutic strategy for the prevention of progressive alveolar bone loss.