Miracle-dz/UniFAR-FTUs huggingface dataset:
Review of Helicobacter pylori Infection and Chronic Renal Failure

Chronic renal failure patients receiving hemodialysis and continuous ambulatory peritoneal dialysis often encounter gastrointestinal troubles over their long treatment period. Helicobacter pylori infection has close association with development of peptic ulcer, gastric cancer and gastric lymphoma, and is thought to be one of the major risk factors for gastrointestinal troubles in dialysis patients. However, it is unclear whether H. pylori infection is directly associated with progression of renal dysfunction and prognosis of chronic renal failure patients. Recent consensus shows that the prevalence of H. pylori infection in chronic renal failure patients is significantly lower than in subjects with normal renal function. In the natural history of H. pylori infection in hemodialysis patients, the prevalence of infection decreases as dialysis periods progressed, in particular within the first four years after the start of treatment. However, the chance of natural eradication becomes rare for patients receiving dialysis treatment for a long time. Moreover, chronic renal failure patients with H. pylori infection have a higher incidence of gastroduodenal diseases, and therefore, are recommended to receive eradication therapies, especially for those receiving treatment for a long time and with higher risks of complication. Intensive endoscopic check‐ups for the prevention of gastrointestinal events and the discovery of peptic ulcer and neoplastic diseases at an early phase may be required.
IL‐7 is superior to IL‐2 for ex vivo expansion of tumour‐specific CD4+ T cells

It is well established that tumours hinder both natural and vaccine‐induced tumour‐specific CD4+ T‐cell responses. Adoptive T‐cell therapy has the potential to circumvent functional tolerance and enhance anti‐tumour protective responses. While protocols suitable for the expansion of cytotoxic CD8+ T cells are currently available, data on tumour‐specific CD4+ T cells remain scarce. We report here that CD4+ T cells sensitized to tumour‐associated Ag in vivo, proliferate in vitro in response to IL‐7 without the need for exogenous Ag stimulation and accumulate several folds while preserving a memory‐like phenotype. Both cell proliferation and survival accounts for the outgrowth of tumour‐sensitized T cells among other memory and naive lymphocytes following exposure to IL‐7. Also IL‐2, previously used to expand anti‐tumour CTL, promotes tumour‐specific CD4+ T‐cell accumulation. However, IL‐7 is superior to IL‐2 at preserving lymphocyte viability, in vitro and in vivo, maintaining those properties, that are required by helper CD4+ T cells to confer therapeutic efficacy upon transplantation in tumour‐bearing hosts. Together our data support a unique role for IL‐7 in retrieving memory‐like CD4+ T cells suitable for adoptive T‐cell therapy.
An update on PERIOPERATIVE ANAPHYLAXIS

Anaphylaxis is a rare and potentially fatal complication with a wide spectrum of clinical presentations. The ability to recognise and treat it in the perioperative setting is imperative for every anaesthesiologist. According to the European Academy of Allergy and Clinical Immunology, anaphylaxis is defined as a severe, potentially life-threatening systemic hypersensitivity reaction. The estimated incidence of perioperative anaphylaxis is 1 in 10,000–20,000 anaesthetic procedures, with the overall mortality rate for anaphylaxis being less than 0.001%. 18 JAN 2016
Effect of Naphthalene Acetic Acid on Adventitious Root Development and Associated Physiological Changes in Stem Cutting of Hemarthria compressa

In order to find a way to induce rooting on cuttings of Hemarthria compressa cv. Ya’an under controlled conditions, a project was carried out to study the effect of naphthalene acetic acid (NAA) on rooting in stem cuttings and related physiological changes during the rooting process of Hemarthria compressa. The cuttings were treated with five concentrations of NAA (0, 100, 200 300, 400 mg/l) at three soaking durations (10, 20, 30 minutes), and cuttings without treatment were considered as control. Samples were planted immediately into pots after treatment. IAA-oxidase (IAAO) activity, peroxidase (POD) activity and polyphenol oxidase (PPO) activity were determined after planting. Results showed that NAA had positive effect on rooting at the concentration of 200 mg/l compared to other concentrations at 30 days after planting (DAP). Among the three soaking durations, 20 minutes (min) of 200 mg/l NAA resulted in higher percentages of rooting, larger numbers of adventitious roots and heavier root dry weight per cutting. The lowest IAAO activity was obtained when soaked at 200 mg/l NAA for 20 min soaking duration. This was consistent with the best rooting ability, indicating that the lower IAAO activity, the higher POD activity and PPO activity could be used as an indicator of better rooting ability for whip grass cuttings and might serve as a good marker for rooting ability in cuttings.
A Meta-Analysis of Organizational Complaint Handling and Customer Responses

Service recovery is a crucial success factor for organizations. Thus, many studies have addressed the issue of post-complaint behavior. Conducting a meta-analysis, the authors test the following path model: ‘‘organizational responses (compensation, favorable employee behavior, and organizational procedures) → justice perceptions (distributive, interactional, and procedural justice) → post-complaint satisfaction (transaction-specific and cumulative satisfaction) → customer behavioral intentions (loyalty and positive word of mouth [WOM]). ’’ The results confirm this model as well as the mediating role of justice perceptions and post-complaint satisfaction. Surprisingly, the results also show that the common contention of distributive justice as the salient driver of service recovery is only true for transaction-specific satisfaction, which in turn reinforces positive WOM. Cumulative satisfaction, however, which is the primary antecedent of customer loyalty, even slightly more depends on interactional justice than on distributive justice. Further, the results show that the relationships between justice perceptions and satisfaction constructs depend on several moderators such as target group, industry, and complaint type. A major managerial implication is the fact that organizations should pay particular attention to distributive justice when complainants are students and to interactional justice when failure is nonmonetary or occurs in service industries. The authors discuss theoretical implications and provide suggestions for future research.
Challenges for the Prevention of Primary and Secondary Stroke. The importance of lowering blood pressure and total cardiovascular risk

It is well established that blood pressure lowering is effective for the primary prevention of stroke and other cardiovascular disorders in subjects with blood pressures as low as 140/90 mmHg, and up to 80 years of age. Despite this knowledge, blood pressure levels are controlled in less than 25% of the hypertensive population worldwide. It has taken longer to prove that blood pressure lowering is equally effective for the prevention of recurrent stroke. The results of PROGRESS (Perindopril Protection Against Recurrent Stroke Study) have confirmed that a perindopril-based regimen in subjects with cerebrovascular disease substantially reduces the incidence of secondary stroke and primary myocardial infarction. It is daunting to recall that it has taken almost two decades for beta-blockers to be widely used for the secondary prevention of myocardial infarction, since widespread use of the PROGRESS regimen would prevent more than half a million strokes worldwide each year. The real challenge now is to implement novel and effective strategies for the control of blood pressure and other cardiovascular risk factors worldwide. Strategies should include lifestyle measures, such as stopping smoking, exercise and reducing overweight. There is a real need to identify hypertensive subjects and treat them with blood pressure lowering drugs for primary prevention. In subjects with established cardiovascular disease, consideration should be given to a range of proven interventions for secondary prevention, such as blood pressure lowering, irrespective of current blood pressure, anti-platelet drugs, statins for lowering cholesterol and glycaemic control in diabetics. Among new strategies to lower overall cardiovascular risk, consideration should be given to the development of single-pill combinations of drugs of known efficacy, including various combinations of ACE inhibitors, diuretics, beta-blockers, aspirin and statins, among others.
Augmented Anti-tumor Effect of Dendritic Cells Genetically Engineered by Interleukin-12 Plasmid DNA

The objective of this study was to genetically engineer dendritic cells (DC) for biological activation and evaluate their anti-tumor activity in a tumor-bearing mouse model. Mouse DC were incubated on the surface of culture dishes which had been coated with the complexes of a cationized dextran and luciferase plasmid DNA complexes plus a cell adhesion protein, Pronectin®, for gene transfection (reverse transfection). When compared with the conventional transfection where DC were transfected in the medium containing the complexes, the level of gene expression by the reverse method was significantly higher and the time period of gene expression was prolonged. Following the reverse transfection of DC by a plasmid DNA of mouse interleukin-12 (mIL-12) complexed with the cationized dextran, the mIL-12 protein was secreted at higher amounts for a longer time period. When injected intratumorally into mice carrying a mass of B16 tumor cells, the DC genetically activated showed significant anti-tumor activity.
Causation by Disconnection

The physical and/or intrinsic connection approach to causation has become prominent in the recent literature, with Salmon, Dowe, Menzies, and Armstrong among its leading proponents. I show that there is a type of causation, causation by disconnection, with no physical or intrinsic connection between cause and effect. Only Hume-style conditions approaches and hybrid conditions-connections approaches appear to be able to handle causation by disconnection. Some Hume-style, extrinsic, absence-relating, necessary and/or sufficient condition component of the causal relation proves to be needed.
Guessing Attacks on Strong-Password Authentication Protocol

Password authentication is the most important and convenient protocol for verifying users to get the system’s resources. Lin et al. had proposed an optimal strongpassword authentication protocol (OSPA) which is a onetime password method. It can protect against the replaying attacks, impersonation attacks, and denial of service attacks. However, the authors shall show that the OSPA protocol is vulnerable to the guessing attacks in this paper.
Profile of transforming growth factor‐beta 1 in patients with dengue haemorrhagic fever

The pathogenesis of dengue haemorrhagic fever (DHF) is incompletely understood but it has been suggested that various cytokines may have a role in the process. In this study the profile of the cytokine Transforming Growth Factor‐beta 1 (TGF‐β1) was investigated in the sera of 79 patients with various grades of dengue illness and in 21 normal healthy controls. Also, TGF‐β1‐specific mRNA was examined in their peripheral blood mononuclear cells (PBMC). The results showed that neither TGF‐β1 protein nor its mRNA were detected in healthy controls. In dengue patients, the TGF‐β1 protein and its mRNA were detected in 96%. However, among the patient groups, the levels of TGF‐β1 were lowest in patients with dengue fever (DF; mean value 315 ± 95 pg/ml) and were highest in patients with DHF grade IV (mean value 1350 ± 280 pg/ml; P = < 0.001). The cytokine appeared during the first four days of illness (304 ± 90 pg/ml) and gradually increased, reaching peak levels (1050 ± 215 pg/ml) after the 9th day of the illness. Thus TGF‐β1 in the sera and TGF‐β1‐mRNA in the PBMC were present in most of the patients with dengue (96%) but the cytokine levels were highest during the later periods of illness and in patients with DHF grade IV, suggesting a possible role of TGF‐β1 in the pathogenesis of DHF.
Developing Contemporary Teaching Perspectives for EFL Teachers

The article focuses on contemporary perspectives in psycholinguistics that EFL teachers need to develop in order to teach effectively. A perspective explains much on how EFL teachers implement their teaching. These perspectives include: (1) Knowing how language is acquired to teach the language effectively; (2) being aware that what is known about learning in general may be different for learning EFL; (3) holding specific beliefs about learning EFL influence the teaching of EFL; and (4) teaching is assessed by EFL by looking at teachers attitudes about teaching and learning. Given the perspectives, recommendations are provided for EFL teachers.
Making Recovery a Habit: Supportive Socialization Dimensions and Recovery from Mental Illness

Chyrell D. Bellamy, PhD, MSW, is Assistant Clinical Professor and Director of Peer Services and Research, Yale School of Medicine, Department of Psychiatry, Program for Recovery and Community Health, New Haven, Connecticut. Poster presented in part at Habit and Rehabilitation: Promoting Participation, January 31-February 4, 2007, Pacific Grove, California. Address correspondence to Chyrell D. Bellamy at chyrell.bellamy@yale.edu. While listening to and analyzing narratives of consumer providers’ interpretations of their mental illness and recovery, a community narrative took shape—that of consumer providers working to make recovery a habit. This poster presented a qualitative study of 31 individuals with mental illness who worked as consumer providers in mental health self-help and consumer drop-in centers. The purpose was to explore how sociocultural factors influence experiences with mental illness and recovery. The following themes emerged from analysis: (1) Mattering to Others and Self (childhood and adult factors of trauma, abandonment, stigma, and exclusion); (2) Creating Meaning (accepting self and others; social identity through meaningful roles); and (3) Spirituality (affirming self and finding purpose). Participants’ narratives provided illustrative examples of the ways in which individuals recover “self. ” The themes from the narrative analysis were consonant with dimensions of the “Supportive Socialization” model (Davidson et al., 2001). Supportive Socialization encompasses: (1) social inclusion through friendships; (2) feeling like a worthwhile human being through meaningful activity (feelings of meaning and worth derived from giving back); and (3) hopefulness through an affirmative stance (spiritual beliefs, calling, and belief that life is good and thus worth living). According to Davidson et al. (2001), supportive socialization processes are prerequisites for recovery: “When people do not have hope, a sense of self-worth, and a sense of their own efficacy, they will not be equipped to take on the formidable challenges inherent in attempting to cope with, not to mention recovery from, their disorder” (p. 379). The narratives from the individuals in the qualitative study reflected the importance of supported socialization dimensions for individuals recovering from mental illness, providing suggestions on how to make recovery a “habit. ”
Neuropeptides in Eating Disorders

Abstract The past decade has witnessed a dramatic acceleration in research on the role of the neuropeptides in the regulation of eating behavior and body weight homeostasis. This expanding research focus has been driven in part by increasing public health concerns related to obesity and the eating disorders anorexia nervosa (AN) and bulimia nervosa (BN). Preclinical advances have been facilitated by the development of new molecular and behavioral research methodologies. With a focus on clinical investigations in AN and BN, this article reviews research on selected hypothalamic and gut-related peptide systems with prominent effects on eating behavior. Studies of the orexigenic peptides neuropeptide Y and the opioid peptides have shown state-related abnormalities in patients with eating disorders. With respect to gut-related peptides, there appears to be substantial evidence for blunting in the meal-related release of the satiety promoting peptide cholecystokinin in BN. Fasting plasma levels of the orexigenic peptide ghrelin have been found to be elevated in patients with AN. As discussed in this review, additional studies will be needed to assess the role of nutritional and body weight changes in neuropeptide alterations observed in symptomatic eating disorder patients, and to identify stable trait-related abnormalities in neuropeptide regulation that persist in individuals who have recovered from an eating disorder.
Current role of treatment in men with lower urinary tract symptoms combined with overactive bladder

Lower urinary tract symptoms (LUTS) and benign prostatic hyperplasia (BPH) are highly prevalent in older men. The storage subcategory of LUTS is synonymous with overactive bladder (OAB) syndrome, which is an empirical diagnosis. Traditionally, alpha-blockers are widely prescribed to manage the LUTS of BPH, although storage symptoms may persist in many men despite treatment. Therefore, because therapies that target the prostate often fail to alleviate storage symptoms, they may not be the appropriate therapy for OAB. In past years, most physicians appeared to give more weight in elderly men to voiding symptoms than to storage symptoms and to be more concerned with initial treatment with anticholinergics for males with storage symptoms. Considering the recent increase in data on the efficacy and safety of combination treatment with alpha receptor antagonists and antimuscarinic agents, the standard pharmacologic treatment of patients with LUTS combined with OAB should be an alpha receptor antagonist and an antimuscarinic agent. Beta-3 adrenoreceptor agonists may also potentially be useful for the treatment of male LUTS combined with OAB.
Serological studies with influenza A(H1N1) viruses cultivated in eggs or in a canine kidney cell line (MDCK).

Pairs of influenza A(H1N1) viruses cultivated from the same clinical specimen in canine kidney (MDCK) cells or in embryonated hens' eggs can frequently be distinguished by their reactions with monoclonal antibodies to haemagglutinin and with antibodies in ferret or human sera. Egg-adapted virus, further passaged in MDCK cultures remained "egg-like" in serological characteristics indicating that the differences in their serological reactions were not a direct result of host cell-dependent glycosylation of the haemagglutinin. Haemagglutination-inhibiting (HI) or virus neutralizing antibodies in human sera can be detected more frequently, and to higher titre, in tests employing virus grown exclusively in MDCK cells than in tests with virus adapted to growth in embryonated eggs. Striking differences were detected in the serological reactions in HI tests when sera from ferrets infected with egg-grown virus were tested against a series of strains of influenza A(H1N1) virus isolated in 1983 and adapted to growth in eggs. In contrast, sera from ferrets infected with MDCK-derived virus failed to distinguish serologically between the same viruses that had been passaged exclusively in MDCK cells and also revealed relatively small differences between their egg-adapted counterparts.It was concluded that the cell substrate used for virus isolation and cultivation is a factor that should be considered when interpreting the results of strain characterization of influenza A(H1N1) isolates and in sero-surveys using these viruses.
Hand gesture recognition using 3D sensors

The aim of this work is to investigate the problem of static hand gesture recognition using Kinect v2 depth sensor. We have dealt not only with the theory of recognition itself, but also with the use of depth sensors and the latest approaches in this field. We have successfully applied different convolutional neural network architectures to this classification problem and evaluated the impact of kernel size on the recognition score. By creating our own static gesture database, we have gained an objective way of comparing each test method.
Fuzzy Integral Imaging Camera Calibration for Real Scale 3D Reconstructions

In this paper, we present a quantitative analysis of the error in the reconstruction of a 3D scene which has been captured with Synthetic Aperture Integral Imaging system. The 3D information is obtained from 2D images for which the camera parameters are unknown. The model used for calibrating the Integral Imaging camera setup is based on fuzzy systems. These systems provide the opportunity for modeling of conditions which are inherently imprecisely defined. We demonstrate that the error in the 3D reconstruction not only depends on the number of cameras, but also to their relative positions. Our model is applied to a set of images captured experimentally from a real object. A true-color real scale 3D reconstruction is successfully achieved.
CHALLENGING CASE: DEVELOPMENTAL DELAYS AND REGRESSIONS Expressive Language Delay in a Toddler*

CASE Shelly is a 20-month-old white female whose parents thought she was in excellent general health when she came to her pediatrician for a health supervision visit. A developmental survey consisting of focused questions revealed that Shelly spoke only occasionally with a vocabulary limited to five words. Although motor and social skills were age-appropriate, verbal expressions typically consisted of nonintelligable utterances and frequent pointing to objects. She occasionally chatters “as if she had her own language. ” Shelly reportedly responds to directions appropriately, and she appears to hear normal human voices, music, and a telephone ring. Shelly has been in home day care since 10 months of age when her mother returned to work. With four other toddlers, she is cared for by a Spanish-speaking caretaker; her parents speak English at home. She is the only child in her family; her parents remarked that they each had a sibling whose early language acquisition was delayed but as adults did not seem language impaired. Shelly’s prenatal course was complicated by premature contractions treated from 30 weeks gestation with terbutaline. She was delivered at term by a spontaneous vaginal delivery without complications. Apgar scores were 8 at 1 minute and 9 at 5 minutes. On physical examination, Shelly appeared robust. Social and visual engagement occurred easily with her mother and the examiner. Growth parameters were at the 50th percentile. The examination was normal, including her tympanic membranes (normal appearance and compliance), palate, pharynx, facial structure, and neurological assessment. Gross and fine motor skills were documented at the 20to 24month level. She responded to commands given by her mother and the examiner. She was able to point to pictures of objects on request and correctly pointed to three body parts. When asked to “go get your shoes and sit down,” she completed the task after the second request. Throughout the interview and examination, Shelly did not say any specific words. However, she pointed to a toy and doll she wanted during a play situation.