Miracle-dz/UniFAR-FTUs huggingface dataset:
Mother–Father Dyad Conflict Strategy Clusters: Implications for Emerging Adults

Research has examined the different parenting styles that are present during emerging adulthood; however, less is known about potential parental conflict strategies that emerging adults may be experiencing during this developmental time period. Conflict strategies are conceptualized in the current study as parents’ efforts to regulate, correct, or enforce a consequence in response to their emerging adult child’s behavior. Previous research on discipline during childhood and adolescence has suggested the use of harsh discipline (e.g., use of physical force) leads to negative outcomes for children. Despite evidence linking harsh discipline methods to harmful outcomes in various developmental periods and suggested influence of parents in emerging adulthood, very little is known about how parents handle conflict with their emerging adult children. Thus, the present study investigated parental conflict strategies and mental health outcomes of emerging adults. Results revealed a significant parent–child gender interaction for non-violent strategies and psychological aggression. Moreover, results indicated that emerging adult children of parents who utilize similar levels of aggressive methods reported greater psychological problems. The findings from the current study underscore parents’ use of conflict strategies when interacting with their emerging adult children, and further emphasize the importance of future research in this area.
Epidemiology of Pseudomonas cepacia colonization among patients with cystic fibrosis

Colonization with Pseudmonas cepacia in patients with cystic fibrosis (CF) has been associated with increased morbidity and early death, compared with colonization by P. aeruginosa. The mode of acquisition of P. cepacia is not fully understood, although person‐to‐person spread appears likely. Recent epidemiologic studies support the importance of social contact in the spread of P. cepacia among patients with CF. This study was undertaken to investigate the epidemiology of P. cepacia colonization among patients with CF attending the CF clinic at our center. Isolates of P. cepacia were collected from patients at two CF treatment centers, including ours. Additional isolates were collected from patients without CF in the hospital ICU, from other teaching hospitals, and from the environment. Profiles of enzymes were obtained by ultrathin polyacrylamide gel electrophoresis of P. cepacia extracts. A predominant electromorphic type (ET) was found among P. cepacia isolates from patients at both centers, suggesting a common source or person‐to‐person transmission. The majority of hospital isolates fell into a single, different ET. Surveillance swabs of respiratory equipment at our CF clinic did not grow P. cepacia. Attendance of patients at CF summer camp correlated strongly with P. cepacia colonization (P < 0.0001). Pediatr Pulmonol. 1994;18:108–113. © 1994 Wiley‐Liss, Inc.
Partial A1 Adenosine Receptor Agonist Regulates Cardiac Substrate Utilization in Insulin-Resistant Rats in Vivo

Reducing the availability and uptake of fatty acids is a plausible pharmaceutical target to ameliorate glucose intolerance and insulin resistance. CVT-3619 [2-{6-[((1R,2R)-2-hydroxycyclopentyl) amino]purin-9-yl(4S,5S,2R,3R)-5-[(2-fluorophenylthio)methyl]oxolane-3,4-diol] is a partial A1 adenosine receptor agonist with antilipolytic properties. Aims of the present study were to examine the acute effects of CVT-3619 on whole-body and cardiac glucose and fatty acid kinetics in vivo in normal and diet-induced insulin-resistant rats. Male Sprague-Dawley rats were fed either a chow (CH) or high-fat (HF) diet for 4 weeks. Catheters were then chronically implanted in the carotid artery and jugular vein for sampling and infusions, respectively. After 5 days of recovery, fasted animals (10 h) received either saline or CVT-3619 (0.4 mg/kg bolus + 1 mg/kg/h). Indices of glucose and fatty acid utilization were obtained by the administration of 2-deoxy[14C]glucose and [9,10-3H]-(R)-2-bromopalmitate. HF feeding resulted in elevated, fasting insulin and free fatty acid (FFA) levels compared with CH. CVT-3619 caused a 64 and 86% reduction of FFA and insulin in HF (p < 0.05) but less (N.S.) in CH diet-fed animals. In HF diet-fed rats, CVT-3619 increased whole-body glucose clearance with no change in fatty acid kinetics. Likewise, analysis of cardiac tissue metabolism showed that CVT-3619 caused an increased glucose but not fatty acid clearance in HF-fed animals. Results show that the acute administration of CVT-3619 lowers circulating fatty acid levels, leading to improved whole-body and cardiac glucose clearance in a model of diet-induced insulin resistance. As such, CVT-3619 may be a treatment option for the restoration of substrate balance in the insulin-resistant heart.
View Generation by Ray-Space Method in Circular Camera Setup for FTV

In this paper, we propose a novel method to generate free viewpoint image in circular camera setup. The proposed method is based on the Ray-Space method, and we can generate a free viewpoint image from the Ray-Space which is not dense enough by interpolation techniques. In a past method [1], a captured image is regarded as an orthographic image to simplify the interpolation process. However, this is an approximate means, and does not work in the case that an object is big compared to a circle or the object is not at the center of a circle. In contrast, the proposed method can be applied to the case of perspective camera model by analyzing the trajectory of a ray in the Ray Space. In experiment with a real sequence captured at every 6 or 12 degrees, we set the virtual camera at user's choice and generated the image from that viewpoint successfully.
Evaluation of acupuncture for pain control after oral surgery: a placebo-controlled trial.

BACKGROUND Acupuncture is increasingly being used by the general population and investigated by conventional medicine; however, studies of its effects on pain still lack adequate control procedures. OBJECTIVES To evaluate the (1) efficacy of Chinese acupuncture in treating postoperative oral surgery pain, (2) validity of a placebo-controlled procedure, and (3) effects of psychological factors on outcomes. DESIGN Randomized, double-blind, placebo-controlled trial. SETTING Dental School Outpatient Clinic, University of Maryland at Baltimore. PARTICIPANTS Thirty-nine healthy subjects, aged 18 to 40 years, assigned to treatment (n=19) and control (n=20) groups. MAIN OUTCOME MEASURES Patients' self-reports of time until moderate pain, time until medication use, total pain relief, pain half gone, and total pain medication consumption. RESULTS Mean pain-free postoperative time was significantly longer in the acupuncture group (172.9 minutes) than in the placebo group (93.8 minutes) (P=.01), as was time until moderate pain (P=.008). Mean number of minutes before requesting pain rescue medication was significantly longer in the treatment group (242.1 minutes) than in the placebo group (166.2 minutes) (P=.01), as was time until medication use (P=.01). Average pain medication consumption was significantly less in the treatment group (1.1 tablets) than in the placebo group (1.65 tablets) (P=.05). There were no significant between-groups differences on total-pain-relief scores or pain-half-gone scores (P>.05). Nearly half or more of all patients were uncertain of or incorrect about their group assignment. Outcomes were not associated with psychological factors in multivariate models. CONCLUSIONS Acupuncture is superior to the placebo in preventing postoperative dental pain; noninsertion placebo procedure is valid as a control.
A 62-MeV proton beam for the treatment of ocular melanoma at Laboratori Nazionali del Sud-INFN

At the Istituto Nazionale di Fisica Nucleare-Laboratori Nazionali del Sud (INFN-LNS) in Catania, Italy, the first Italian protontherapy facility, named Centro di AdroTerapia e Applicazioni Nucleari Avanzate (CATANA) has been built in collaboration with the University of Catania. It is based on the use of the 62-MeV proton beam delivered by the K=800 Superconducting Cyclotron installed and working at INFN-LNS since 1995. The facility is mainly devoted to the treatment of ocular diseases like uveal melanoma. A beam treatment line in air has been assembled together with a dedicated positioning patient system. The facility has been in operation since the beginning of 2002 and 66 patients have been successfully treated up to now. The main features of CATANA together with the clinical and dosimetric features will be extensively described; particularly, the proton beam line, that has been entirely built at LNS, with all its elements, the experimental transversal and depth dose distributions of the 62-MeV proton beam obtained for a final collimator of 25-mm diameter and the experimental depth dose distributions of a modulated proton beam obtained for the same final collimator. Finally, the clinical results over 1 yr of treatments, describing the features of the treated diseases will be reported.
Intellectual property rights protection and export quality

Purpose - This paper aims to investigate the impact of IPR protection on its ability to enhance domestic export quality. Design/methodology/approach - This paper provides a testable framework to explain the impact of IPR protection on export quality. Research and development (R&D) spending and foreign direct investment (FDI) are positively correlated with a country’s export quality. Furthermore, intellectual property protection can induce more FDI and R&D spending. Therefore, we expect that there may be an indirect relationship between intellectual property protection and export quality (See Fig. 1). Findings - The empirical results suggest that the influence paths of IPR protection on export quality are different between developed and developing countries. FDI plays a mediating role in the relationship between IPR protection and export quality in developing countries, while this mediating effect in developed countries is dependent on R&D and FDI. In addition, this impact is statistically significant in high technology industries. Especially, IPR protection plays an extraordinary important role in enhancing the export quality of differentiated high-technology products. Originality/value - This paper contributes to the literature in several ways. First, this is the first empirical analysis focusing on the influence path of IPR protection on export quality. We find that the hypothesis is supported by the positive and significant interaction coefficients of IPR protection with FDI and R&D. Second, we explore that the influence path of IPR protection on export quality may vary with the level of economic development. Third, this paper examines the effect of IPR protection on export quality in different industries.
Information Leakage through Mobile Motion Sensors: User Awareness and Concerns

Smart phones and wearable devices have replaced personal computers and desktops as the primary platform for accessing online applications and services. However, these mobile devices bring forth new and additional forms of security and privacy risks, which were non-existent in traditional personal computers. For instance, several recent research efforts have shown that motion sensors such as accelerometer and gyroscope on-board these mobile and wearable devices can be maliciously used to infer private information from users’ keystrokes (e.g., PINs and passwords). The problem is that, unlike traditional security and privacy risks that are typically associated with personal computers, most users may not be aware of these novel risks associated with mobile devices. An adversary may use this lack of user-awareness to target specific user-demographics for successfully carrying out such attacks. There has been some progress in the direction of protection mechanisms against such attacks, however, without user-awareness these protection mechanisms are unlikely to be used effectively (if at all). In order to further understand these issues, we conduct a structured and comprehensive user-study involving users from diverse demographic backgrounds to investigate userawareness and perceptions related to mobile motion sensor based privacy risks, and how these vary across different demographics. By means of our study, we also gain insight on users’ expectations from defense mechanisms that can protect against such attacks. Results of our study can be used to increase awareness (about such risks) among the less-aware user demographies, and in designing effective and usable protection mechanisms as per user-expectations.
Studies of Placental Morphogenesis I. Radioautographic Studies of Human Placenta Utilizing Tritiated Thymidine.∗

Summary Portions of human placental tissue have been studied by radioautography utilizing tritiated thymidine. Thymidine uptake could be demonstrated in cytotrophoblast, villous mesenchyme and vascular endothelium but not in the syncytiotrophoblast. This finding suggests that amitotic division of the syncytiotrophoblast does not play a prominent role in the derivation of this cellular layer in the human placenta of 14-18 weeks gestational age.
Elevated Myeloid: Plasmacytoid Dendritic Cell Ratio Associates With Early Acute Cellular Rejection in Pediatric Small Bowel Transplantation

Background. Acute cellular rejection affects more than 60% of children after small bowel transplantation (SBTx). Dendritic cells (DCs) are potent antigen-presenting cells, modulate immune responses to gut microbes, and may serve as markers of rejection-prone small bowel transplantation (SBTx). Methods. Myeloid CD11c+ DC (MDC), which may have inflammatory functions, and plasmacytoid CD123+ DC (PDC), which may have tolerogenic potential, were measured by flow cytometric analysis, longitudinally (pretransplant, and at days 1 to 60, 61 to 200 posttransplant) in 23 children after SBTx. All children received cadaveric allografts with rabbit anti-human thymocyte globulin induction and steroid-free tacrolimus maintenance therapy. Rejectors were those children (n=16), who experienced biopsy-proven acute cellular rejection within 60 days of SBTx. Results. Of 69 maximum possible observations, 62 were available for analysis. Among rejectors, a significantly higher MDC:PDC ratio (P=0.004) was associated with numerically higher MDC counts and significantly lower PDC frequencies (P=0.017) during the 1- to 60-day time period, compared with nonrejectors. Logistic regression analysis, leave-one-out cross-validation, and receiver operating characteristic analysis revealed that MDC:PDC ratio more than or equal to 1.52 was associated with rejector status with sensitivity/specificity of 86/67% during the 1- to 60-day risk period for early SBTx rejection. Repeated measures analysis showed a significantly higher MDC:PDC ratio (P=0.043, F-test) among rejectors, compared with nonrejectors in cumulative data for pre-SBTx and 1- to 60-day time points. No correlation was seen between DC subsets and tacrolimus blood concentration at any time point. Conclusions. We conclude that an elevated MDC:PDC ratio associates with early small bowel allograft rejection and may, therefore, identify at-risk recipients in the clinic.
Mammalian plasma membrane proteins as potential biomarkers and drug targets

Defining the plasma membrane proteome is crucial to understand the role of plasma membrane in fundamental biological processes. Change in membrane proteins is one of the first events that take place under pathological conditions, making plasma membrane proteins a likely source of potential disease biomarkers with prognostic or diagnostic potential. Membrane proteins are also potential targets for monoclonal antibodies and other drugs that block receptors or inhibit enzymes essential to the disease progress. Despite several advanced methods recently developed for the analysis of hydrophobic proteins and proteins with posttranslational modifications, integral membrane proteins are still under‐represented in plasma membrane proteome. Recent advances in proteomic investigation of plasma membrane proteins, defining their roles as diagnostic and prognostic disease biomarkers and as target molecules in disease treatment, are presented.
DDT and associated compounds.

ortho,para' -IDE 50293 a,aBis(para-chlorophenyl )-ß,ß,ß-trichloroethane; 1,I-bis(para-chlorophenyl)-2,2,2-trichloroethane; 2,2-bis(para-chlorophenyl)-I,I,I-trichloro-ethane; 1,I-bis(4-chlorophenyl)-2,2,2-trichloroethane; DDT; 4,4'DDT; para,para' -dichlorodiphenyltrichloroethane; 4,4' -dichlorodiphenyl trichloroethane; para,para' -dichlorodiphenyl trichloromethylmethane; ENT 1506; OMS 0016; 1,1,I-trichloro-2,2-bis(para-chlorophenyl)ethane; 1,1, I-trichloro-2,2-bis( 4,4' -dichlorodiphenyl)ethane; 2,2,2-trichloro-l, I-bis( 4-chlorophenyl)ethane; 1,1, I-trichloro-2,2-bis( 4chlorophenyl)ethane (IUPAC); trichlorobis( 4' -chlorophenyl)ethane; i, i' . (2,2,2trichloro.ethylidene )bis( 4.chlorobenzene)
Molecular Characterization of a Cytoplasmic Dynein from Dictyostelium

Cytoplasmic dynein is a high molecular weight, microtubule‐based mechanochemical ATPase that is believed to provide motive force for a number of intracellular motilities, including transport of membrane‐bound organelles. Cytoplasmic dynein also localizes to the mitotic spindles of some organisms and to the kinetochore regions of some condensed chromosomes, where it may play an active role in spindle assembly, spindle position, and/or chromosome movement during cell division. Despite active research efforts from a number of laboratories, little detail is yet available about dynein‐based cellular activities. This paper describes our efforts to characterize cytoplasmic dynein from Dictyostelium and to use this protist as a molecular genetic factory to probe structure‐function relationships of this molecule.
Intestinal pseudo-obstruction as a presenting symptom of Guillain-Barré syndrome

A 34-year-old man who had in the past enjoyed good health was admitted to the surgical department of our hospital for 1-week history of repeated vomiting and abdominal distension. He also had progressive limb weakness, paresthaesia of limbs and tachycardia for 2 days. Physical examination on admission revealed an alert but distressed patient. His blood pressure was 154/110 mm Hg, his pulse was 132/min and his body temperature was 36.4°C. His abdomen was grossly distended and the bowel sound was absent. His …
Babesia parasites develop and are transmitted by the non-vector soft tick Ornithodoros moubata (Acari: Argasidae)

Ornithodoros moubata ticks were fed on blood infected with Babesia equi. However, the parasites were quickly cleared as evidenced by the disappearance of B. equi-specific ribosomal RNA from the ticks. We hypothesized that if the Babesia parasite can escape midgut-associated barriers a non-vector tick can become infected with Babesia. To test this hypothesis, B. equi parasite-infected blood from in vitro culture was injected into the haemocoel of ticks. B. equi-specific rRNA was surprisingly detected 45 days after injection even in the eggs. Babesia-free dogs were infested with O. moubata ticks that were infected by inoculation with B. gibsoni-infected red blood cells. Parasitaemia and antibody production against Bg-TRAP of B. gibsoni increased gradually. These results indicate that O. moubata may be a useful vector model for Babesia parasites and also a very important tool for studies on tick immunity against Babesia parasites and tick-Babesia interactions.
Evidence-based practice and research utilisation: perceived research knowledge, attitudes, practices and barriers among Australian paediatric occupational therapists.

BACKGROUND/AIM Evidence-based practice (EBP) and research utilisation (RU) are promoted as ways for clients to receive the best level of care. However, limited research has evaluated the use of these approaches by occupational therapists. This study investigated the knowledge, attitudes, practices of and barriers to EBP and RU of a group of paediatric occupational therapists from Australia. METHODS Questionnaires were received from 138 participants (response rate 46%) who completed the Research Knowledge, Attitudes and Practices of Research Survey, the Edmonton Research Orientation Survey and the Barriers to Research Utilisation Scale. RESULTS The participants held positive attitudes towards research, and were willing to access new information to guide practice approaches. However, participants were less confident in their research knowledge and practices and implemented research findings into clinical practice. Multiple barriers to RU were perceived, particularly associated with the presentation and accessibility of research. Participants reported limited engagement in conducting research studies, although the majority of the participants reported implementing the findings of research into their clinical practice to some extent. CONCLUSION Additional research education and support within organisations would be beneficial to ensure that children and families are receiving occupational therapy services that are based on sound, high-quality research evidence. The findings of this study provide insight into the perceived research knowledge, attitudes, practices of and barriers to Australian paediatric occupational therapists, enabling specific strategies to be implemented to increase the use of EBP and RU within the profession.
An overview of the beneficial cardiovascular effects of thiazolidinediones

Cardiovascular disease is a major cause of morbidity and mortality in people with diabetes and those with the metabolic syndrome. With the rising prevalence of these disorders that is now reaching epidemic proportions around the globe, cardiovascular disease is also expected to rise substantially. Although lifestyle and dietary interventions are the first-line approaches in the management of diabetes and the metabolic syndrome, pharmacotherapy is almost always necessary to achieve optimal control of glycemia, elevated blood pressure, microalbuminuria, dyslipidemia and other associated cardiovascular disease risk factors. Therapeutic agents that have beneficial cardiovascular effects are attractive choices in treating these high-risk patients. Thiazolidinediones have recently gained momentum due to an increase in interest in their insulin-sensitizing, pleiotrophic effects and their potential to reduce the risk of cardiovascular disease in people with diabetes and reduce diabetes itself. In this article, the beneficial cardiovascular effects of thiazolidinediones in people with insulin resistance and diabetes shall be reviewed, highlighting their antiatherosclerotic and anti-inflammatory role together with their potential effects on dyslipidemia, visceral obesity, hypertension and microalbuminuria.