Miracle-dz/UniFAR-FTUs huggingface dataset:
Anti-patterns and the energy efficiency of Android applications

The boom in mobile apps has changed the traditional landscape of software development by introducing new challenges due to the limited resources of mobile devices, e.g., memory, CPU, network bandwidth and battery. The energy consumption of mobile apps is nowadays a hot topic and researchers are actively investigating the role of coding practices on energy efficiency. Recent studies suggest that design quality can conflict with energy efficiency. Therefore, it is important to take into account energy efficiency when evolving the design of a mobile app. The research community has proposed approaches to detect and remove anti-patterns (i.e., poor solutions to design and implementation problems) in software systems but, to the best of our knowledge, none of these approaches have included anti-patterns that are specific to mobile apps and--or considered the energy efficiency of apps. In this paper, we fill this gap in the literature by analyzing the impact of eight type of anti-patterns on a testbed of 59 android apps extracted from F-Droid. First, we (1) analyze the impact of anti-patterns in mobile apps with respect to energy efficiency; then (2) we study the impact of different types of anti-patterns on energy efficiency. We found that then energy consumption of apps containing anti-patterns and not (refactored apps) is statistically different. Moreover, we find that the impact of refactoring anti-patterns can be positive (7 type of anti-patterns) or negative (2 type of anti-patterns). Therefore, developers should consider the impact on energy efficiency of refactoring when applying maintenance activities.
An Ecological Risk-Factor Examination of Suicide Ideation and Behavior of Adolescents

Using an ecological risk-factor approach, this study sought to identify risk factors related to suicidal behavior in a sample of 14,922 adolescents (11,027 European American adolescents and 3,895 African American adolescents) drawn from Michigan. Logistic regression analyses were used to determine significant predictors and to calculate a cumulative risk analysis. For both African American and European American males, risk factors related to frequent suicidal ideation and suicidal behavior were found at three levels of the social ecology: individual, family, and extrafamilial. Risk factors were also detected at all three levels of the ecology for both African American and European American females in terms of suicide attempts but not in terms of frequent suicidal thoughts. More similarities were found between the two ethnic groups and between males and females in terms of risk factors for suicidal ideation and attempted suicide. Results lend support to the use of an ecological risk-factor model for examining suicidal thoughts and attempts.
Visual attention to subtitles when viewing a cartoon by deaf and hearing children: an eye-tracking pilot study

Watching a subtitled programme is a complex activity, as it entails paying attention to various stimuli simultaneously, some of which are visual (images and subtitles) and others auditory (oral language and background sounds). The aim of this study is to analyse the ocular movement of a group of children including both hearing and deaf children when watching a television cartoon using an eye tracker. The sample comprises 22 children (11 of whom are deaf and 11 of whom are hearing) aged between seven and 11. The results show that both hearing and deaf children spend more time looking at the images than at the subtitles, with the character's lips being the facial feature to which they pay most attention. Participant age and reading speed are variables that significantly affect the degree of attention paid to subtitles: the youngest children with the slowest reading speed lose their attention as the cartoon progresses. However, participants' auditory condition (deaf or hearing) does not show significant differences regarding maintaining attention on subtitles.
Lower Zinc Bioavailability May Be Related to Higher Risk of Subclinical Atherosclerosis in Korean Adults

Background There is a proposed link between dietary zinc intake and atherosclerosis, but this relationship remains unclear. Phytate may contribute to this relationship by influencing zinc bioavailability. Objective The aim of this study is to examine the relationship between zinc bioavailability and subclinical atherosclerosis in healthy Korean adults. Materials and Methods The present cross-sectional analysis used baseline data from the Korean multi-Rural Communities Cohort Study (MRCohort), which is a part of The Korean Genome Epidemiology Study (KoGES). A total of 5,532 subjects (2,116 men and 3,416 women) aged 40 years and older were recruited from rural communities in South Korea between 2005 and 2010. Phytate:zinc molar ratio, estimated from a food-based food frequency questionnaire (FFQ) of 106 food items, was used to determine zinc bioavailability, and carotid intima media thickness (cIMT) and pulse wave velocity (PWV) were measured to calculate the subclinical atherosclerotic index. Results We found that phytate:zinc molar ratio is positively related to cIMT in men. A higher phytate:zinc molar ratio was significantly related to an increased risk of atherosclerosis in men, defined as the 80th percentile value of cIMT (5th vs. 1st quintile, OR = 2.11, 95% CI 1.42-3.15, P for trend = 0.0009), and especially in elderly men (5th vs. 1st quintile, OR = 2.58, 95% CI 1.52-4.37, P for trend = 0.0021). We found a positive relationship between phytate:zinc molar ratio and atherosclerosis risk among women aged 65 years or younger. Phytate:zinc molar ratio was not found to be related to PWV. Conclusions Lower zinc bioavailability may be related to higher atherosclerosis risk.
A fully planarized 6-level-metal CMOS technology for 0.25-0.18 micron foundry manufacturing

A 0.25 /spl mu/m CMOS technology, with 6 layers of fully planarized interconnect, has been developed for versatile, flexible, and fast turn-around foundry manufacturing. A 0.6 /spl mu/m layout pitch has been successfully demonstrated for active, gate poly, and first metal layers. The 0.25 /spl mu/m, 50 A Tox and the 0.35 /spl mu/m, 65 A Tox devices were designed to support the 2.5 V core and the 3.3 V I/O circuits respectively on the same chip. In addition, high-performance 0.18 /spl mu/m, 40 A Tox transistors are also available for low-power applications at 1.8 V Vcc. Gate-delay is 40 p-sec at 2.5 V for the 0.25 /spl mu/m device, and 35 p-sec at 1.8 V for the 0.18 /spl mu/m device. The embedded 6 T SRAM cell size is 6.34 /spl mu/m/sup 2/. Considerations in process architecture and device design, relevant to foundry manufacturing, are also addressed on this 6-level-metal 0.25 /spl mu/m CMOS technology.
Reactive change and atypical squamous cells of undetermined significance in papanicolaou smears: A cytohistologic correlation

The purposes of this study were to delineate morphologic criteria for the terms reactive/reparative change (RC) and atypical squamous cells of undetermined significance (ASCUS), which were proposed by the Bethesda System, and to evaluate the impact of the new terminology on patient management. Using criteria defined in this article, 88 cervical smears originally reported as “atypia” were reclassified as RC (57) and ASCUS (31). Correlation with the colposcopically directed biopsies was as follows: 3/57 RC showed condyloma and 19/31 ASCUS had squamous lesions (14 condyloma, four mild, and one moderate dysplasia). The remainder of the cases had either cervicitis or no significant abnormality histologically. Using the proposed criteria, 61.3% of ASCUS correlated with positive biopsies, compared to 5.2% of the RC cases. Our results indicate that patients with smears showing RC are significantly less likely to have a squamous lesion as compared to those showing ASCUS, and therefore may be managed more conservatively.
Isolation of Synaptic Vesicles

Synaptic vesicles are the most abundant secretory organelle in eukaryotic neural cells. Synaptic vesicles are physically distinct from other membrane‐bound organelles because they are small, spherical, and highly uniform in size with a diameter of about 40 nm. Synaptic vesicles also have a characteristically low density because water and phospholipids account for 88% of an individual synaptic vesicle's weight. The homogeneous size and density of the synaptic vesicle are characteristics that are exploited in most synaptic vesicle isolation procedures. Synaptic vesicles are purified by isopycnic/velocity sedimentation and size‐based purification schemes. However, protocols differ in the tissue source of vesicles, the way the tissue is homogenized, and the way the vesicles are fractionated. This unit describes two well‐characterized and widely used synaptic vesicle isolation procedures that are capable of generating membrane fractions that are 20 to 30 times enriched in synaptic vesicles.
Developmental and Individual Differences in Children's Ability to Distinguish Reality from Fantasy

The present study focuses on children's developing ability to categorize real and pretend events, their understanding regarding the permanence of the state of pretense, and the potential effects that emotional tones have on these abilities. Children's involvement in imagination was also assessed as a possible factor contributing to individual differences in reality/fantasy understanding. Sixty male and female children selected from university preschool and kindergarten classes judged happy, neutral, and frightening pictures selected from children's books according to whether they believed that the event could happen in real life. Findings show that kindergartners perform significantly better than preschoolers in distinguishing real from pretend events. Overall, children made significantly fewer correct distinctions between reality and fantasy for the frightening pictures than for both the happy and neutral pictures. Individual difference analyses between children judged to be differentially involved in fantasy did not reveal any differences in their ability to distinguish between real and pretend events. Theoretical and practical implications of these findings are discussed.
Equity recognition of mandatory accounting changes: the case of transitional goodwill impairment losses

This study investigates if and how the use of the retroactive method to account for a mandatory accounting change affects a firm's measurement and recognition choices. We examine if reporting incentives and constraints are associated with the magnitude of transitional goodwill impairment losses reported by Canadian firms implementing Section 3062 on purchased goodwill. Our results indicate firms have an incentive to both overstate and understate transitional goodwill impairment losses. We also show that financially literate and independent audit committees constrain managerial opportunism. Copyright © 2008 ASAC. Published by John Wiley & Sons, Ltd.
User activity detection in massive random access: Compressed sensing vs. coded slotted ALOHA

Machine-type communication services in mobile cellular systems are currently evolving with an aim to efficiently address a massive-scale user access to the system. One of the key problems in this respect is to efficiently identify active users in order to allocate them resources for the subsequent transmissions. In this paper, we examine two recently suggested approaches for user activity detection: compressed-sensing (CS) and coded slotted ALOHA (CSA), and provide their comparison in terms of performance vs resource utilization. Our preliminary results show that CS-based approach is able to provide the target user activity detection performance with less overall system resource utilization. However, this comes at a price of lower energy-efficiency per user, as compared to CSA-based approach.
A quantum of neurotransmitter causes minis in multiple postsynaptic cells at the Caenorhabditis elegans neuromuscular junction

The polyadic synapse, where a single presynaptic active zone associates with two or more postsynaptic cells, exists in both mammals and invertebrates. An important but unresolved question is whether synaptic transmission occurs between the presynaptic site and its various postsynaptic partners. Using the dual whole‐cell voltage clamp technique, we analyzed miniature postsynaptic currents (mPSCs or minis) at the C. elegans neuromuscular junction (NMJ), which is a polyadic synapse. We found that neighboring muscle cells at the same position along the body axis had high frequencies of concurrent mPSCs, which could not be explained by pure chance. Although body‐wall muscle cells are electrically coupled, the high frequency of concurrent mPSCs was not due to electrical coupling because there was no correlation between the frequency of concurrent mPSCs and the degree of electrical coupling; the rise time of concurrent mPSCs was identical to that of nonconcurrent mPSCs but distinct from that of junctional currents (Ij); and a mutant defective in electrical coupling showed normal frequency of concurrent mPSCs. Our analyses suggest that a single quantum of neurotransmitter may cause mPSCs in multiple postsynaptic cells at polyadic synapses, and that high‐fidelity synaptic transmission occurs between the presynaptic site and its various postsynaptic partners. Thus, polyadic synapses could be a distinct mechanism for synaptic divergence and for synchronizing activities of postsynaptic cells. © 2006 Wiley Periodicals, Inc. Develop Neurobiol 67: 123–128, 2007.
Dominant party rule and legislative leadership in authoritarian regimes 1

Authoritarian dominant parties are said to ensure elite loyalty by providing elites with regularized opportunities for career advancement. This article uses data on the distribution of leadership posts in Russia’s regional legislatures (1999–2010) to conduct the first systematic test of this proposition. Loyalty to the nascent hegemonic party, United Russia, is shown to be important in determining a legislator’s chances of being promoted to a leadership position. These findings generate insight into how authoritarian institutions help maintain regime stability and provide a clearer picture of how Russia’s ruling party works.
The antioxidant status of patients subjected to today body irradiation

Background and Purpose: Total body irradiation (TBI) is a routine preconditioning procedure for the treatment of leukemia and aplastic anemia, prior to bone marrow transplantation (BMT). Ionizing radiation generates reactive oxygen derived species (ROS) that can be removed by antioxidants. Our purpose is to determine the antioxidant status of patients undergoing TBI by evaluating the oxidant stress and their antioxidant capacity.
Synthesizing Decentralized Components from a Variant of Live Sequence Charts

Live sequence charts (LSC) is a visual, executable, language for the modeling of reactive systems. Each chart depicts an inter-object scenario arising in the modeled system, partitioned into two: a monitored prechart, and a main chart. Despite the intuitive use of the language, complications arise when one wants to implement an LSC specification with decentralized components. In this paper, we introduce a variant of LSC, called distributed LSC (dLSC), which is targeted for the modeling and synthesis of decentralized systems, composed of several interacting components. While LSCs are commonly interpreted in terms of an interleaved execution of the scenarios in a sequential run, dLSCs employ partially ordered runs. We investigate the expressive power of dLSC compared to an established model of concurrent systems, namely, Petri nets, and show that dLSCs are, computationally, strictly more expressive than low-level Petri nets and subsumed by higher-level Petri nets. Specifically, we present an algorithm that synthesizes, given a dLSC specification, an equivalent token history net, which can serve as an executable implementation of the specification. Most importantly, the implementation is decentralized - components can be automatically extracted from the net. The synthesis of Petri-net components from a dLSC specification is supported by a tool.
Red flag symptoms: detailed account of clinicopathological features in young-onset colorectal cancer

Background/Aims Colorectal cancer has long been considered disease of the West, typically occurring in old age; however, the incidence is rising in Asia. The pattern of disease is quite different in Asia, occurring at a younger age and at an advanced stage. Recognition of disease at an early stage is still a challenge for physicians. Few data are available regarding young-onset colorectal cancer in Pakistan. We conducted this study to fill this gap and provide deeper insight into clinical symptoms and histopathological features of young-onset colorectal cancer. Methods We collected data regarding clinical features by directly interviewing patients and obtaining histopathological data from hospital records. Patients aged less than 50 years were included in the study. Statistical analysis was performed using IBM SPSS version 20.0. Results Results in 105 patients showed mean age at diagnosis was 35.90±9.39, with male predominance; the majority of patients had no family history of colorectal cancer. Most patients had left-sided tumors with advance stage and intermediate grade (grade 2). Mucinous histology was common. Rectal bleeding was the first symptom for left-sided tumors, whereas most of the right-sided lesions presented with sudden obstruction. Conclusions Painless rectal bleeding in the early thirties should alert physicians to advise appropriate investigation, as the majority of young-onset colorectal cancer patients develop painless bleeding 2 to 3 years before appearance of other symptoms.
Neuropeptides and neuropeptide receptors in the Drosophila melanogaster genome.

Recent genetic analyses in worms, flies, and mammals illustrate the importance of bioactive peptides in controlling numerous complex behaviors, such as feeding and circadian locomotion. To pursue a comprehensive genetic analysis of bioactive peptide signaling, we have scanned the recently completed Drosophila genome sequence for G protein-coupled receptors sensitive to bioactive peptides (peptide GPCRs). Here we describe 44 genes that represent the vast majority, and perhaps all, of the peptide GPCRs encoded in the fly genome. We also scanned for genes encoding potential ligands and describe 22 bioactive peptide precursors. At least 32 Drosophila peptide receptors appear to have evolved from common ancestors of 15 monophyletic vertebrate GPCR subgroups (e.g., the ancestral gastrin/cholecystokinin receptor). Six pairs of receptors are paralogs, representing recent gene duplications. Together, these findings shed light on the evolutionary history of peptide GPCRs, and they provide a template for physiological and genetic analyses of peptide signaling in Drosophila.
The development of aggressive behaviour during childhood: What have we learned in the past century?

Research on human aggression has been a flourishing industry in the 20th century. As the attention shifted from an instinctual paradigm to a drive paradigm and a social learning paradigm, what have we learned on the development of aggressive behaviour during childhood? Are children born with an aggressive instinct or do they have to learn to aggress? This question has deep philosophical roots, but it also has important practical implications. Should interventions prevent children from learning to aggress or should they help children learn to inhibit aggressive reactions? Since most of the 20th century work on the development of aggression was concentrated on adolescents and elementary school age children, there appeared to be an implicit assumption that aggression is learned during these developmental periods. It is argued that to understand the origins of aggressive behaviour and prevent chronic cases of physical aggression we will need to focus on the development of aggressive behaviour during the first few years after birth, and differentiate among forms of aggressive behaviour. The form of agressive behaviour that is generally considered more “serious” or “socially unacceptable” (physical aggression) is clearly ontogenetically antecedent to less “serious” forms of aggressive behaviour, such as verbal aggression or indirect aggression. Furthermore, as a rule the frequency of physical aggression appears to decrease with age. However, infants’ physical aggression has generally not been considered developmentally significant. This is probably because of “the weakness of their limbs” and the apparent lack of “intentionality”. To have a relatively complete description of the life-span developmental trajectories of human aggressive behaviour by the end of the 21st century, we will need to start recruiting pregnant women very soon.
Attributions for and consequences of student misbehavior

Background: Effective classroom management is a critical teaching skill and a key concern of educators. As such it has been the focus of much research and as a result educators know a good deal about what happens in physical education class and the actions teachers take to deal with student behavior. Surprisingly, however, we do not know much at all about what teachers believe causes student misbehavior, nor what students say about the same issue. This seems like a critical oversight as how one explains another's behavior determines the individual's reactions to that behavior. Purpose: To examine teacher and student attributions for behavior in physical education class. Participants and setting: Twenty-three secondary physical education teachers (14 males and nine females), and 182 secondary students (100 males and 82 females) from a variety of school districts in the United States. Research design: A descriptive study aimed at examining teacher and student attributions. Maximum variation sampling of schools, teachers, and students was employed to explore the role of context on attribution. Data collection: Teachers were interviewed at a convenient time during the school day while students were interviewed alone or in groups of two or three students during their physical education class. An interview guide structured all discussions. Interviews were recorded and later transcribed. Data analysis: The interview data were analyzed via analytic induction methods to identify and extract common themes. Trustworthiness measures included researcher triangulation and a search for negative cases. Findings: Although the sites and participants in this study were selected for their diversity, comparisons of teachers and students across sites revealed perspectives that were remarkably similar. One key difference between groups was that of attribution for student misbehavior. Teachers most often attributed student misbehavior to unknown or home factors while students were more likely to attribute misbehavior to need for attention and/or a lack of meaningful class content. Both groups largely agreed that student misbehavior negatively affected class time, content, and attitude. Some students cited potential positive outcomes from misbehavior of increased fun and social status. Conclusions: Although teachers and students shared fairly similar perspectives, they disagreed on the reasons for misbehavior and this is a critical difference in perspective that suggests neither group is able and/or willing to ‘own’ the problem of student misbehavior and until it is owned, it will not be solved. There is a need for more reflection by teachers and students to acknowledge their mutual contributions to student misbehavior. Only when both groups start to take ownership of their contribution to the problem of misbehavior can the problem be solved. For teachers, reflection and ownership needs to include taking a broader view of management in order to see the interaction of curriculum and instruction with class management.