Miracle-dz/UniFAR-FTUs huggingface dataset:
Spiritually Integrated Psychotherapy: Understanding and Addressing The Sacred

SPIRITUALLY INTEGRATED PSYCHOTHERAPY UNDERSTANDING AND ADDRESSING THE SACRED. Kenneth Pargament, New York: Guilford, 2007. Pp. 384, Pb, $38.00. Kenneth Pargament begins this work by giving a brief rational for spiritually integrated psychotherapy. The rationale includes the importance of spirituality among many along with the desire to have this dimension included in the therapeutic relationship. Despite these preferences along with research linking healthy spirituality with greater health and a sense of well-being, however, many psychologists leave spirituality out of the conversation, whether due to feelings of uneasiness or lack of preparation from their schooling, which may cause them to be less than effective during treatment. This disconnect, Pargament argues, must be addressed. Part two begins by framing the spiritually integrated approach as one that can be used with a broad authence, including clients and therapists from "diverse religious and non-religious backgrounds" (p. 21). With this in mind Pargament defines spirituality as "the search for the sacred" (p. 32). This discussion is followed by a description of several sacred dimensions and qualities we, as humans, share (e.g., the search for significance, intimacy, etc.), ways individuals hold on to the sacred (e.g., prayer, ritual, relationships etc.), and how spiritual coping mechanisms may help in times of stress. While mainly outlining positive mechanisms Pargament clearly points out how spirituality can become misdirected for some people. This type of dis-integrated spirituality (e.g., lack of scope depth, inflexibility, misdirection etc.) can include the use of 'small gods' (gods limited in some way) and/or 'false gods' (idolatry), by clients, often with unpleasant end results. For those who make it through their spiritual struggles successfully, Pargament contends, a spiritual transformation (e.g., letting go, new purpose, centering of the sacred etc.) often takes place that leads to a well-integrated spirituality (e.g., openness to differences, willingness to engage in spiritual dialogue, sincere desire to share spiritual experiences). Part three, the largest section of the book, explores how to address the sacred as part of clinical practice. Pargament begins by clearly defining what spiritually integrated psychotherapy is: "an approach to treatment that acknowledges and addresses the spirituality of the client, the spirituality of the therapist, and the process of change" (p. 176); he also encourages timid practitioners not to be rejectionists of this aspect but rather gain knowledge, tolerance, and selfawareness which leads to greater authenticity regarding this topic. From here the author outlines various integration techniques, which can be used in a clinical context. Beginning with implicit assessment, (e.g., judicious self-disclosure, openness to discussions of spirituality etc.), the therapist desires to move the process to one where spirituality is expressed more explicitly (e. …
Diagnosis of continuous valued systems in transient operating regions

The complexity of present day embedded systems (continuous processes controlled by digital processors), and the increased demands on their reliability motivate the need for monitoring and fault isolation capabilities in the embedded processors. This paper develops monitoring, prediction, and fault isolation methods for abrupt faults in complex dynamic systems. The transient behavior in response to these faults is analyzed in a qualitative framework using parsimonious topological system models. Predicted transient effects of hypothesized faults are captured in the form of signatures that specify future faulty behavior as higher order time-derivatives. The dynamic effects of faults are analyzed by a progressive monitoring scheme till transient analysis mechanisms have to be suspended in favor of steady state analysis. This methodology has been successfully applied to monitoring of the secondary sodium cooling loop of a fast breeder reactor.
Identification of IKr and Its Trafficking Disruption Induced by Probucol in Cultured Neonatal Rat Cardiomyocytes

The human ether-a-go-go-related gene (hERG) encodes a channel that conducts the rapidly activating delayed rectifier K+ current (IKr), which is important for cardiac repolarization. Mutations in hERG reduce IKr and cause congenital long QT syndrome (LQTS). More frequently, common medications can reduce IKr and cause LQTS as a side effect. Protein trafficking abnormalities are responsible for most hERG mutation-related LQTS and are recently recognized as a mechanism for drug-induced LQTS. Whereas hERG trafficking has been studied in recombinant expression systems, there has been no reported study on cardiac IKr trafficking at the protein level. In the present study, we identified that IKr is present in cultured neonatal rat ventricular myocytes and can be robustly recorded using Cs+ as the charge carrier. We further discovered that 4,4′-(isopropylidenedithio)-bis-(2,6-di-t-butylphenol) (probucol), a cholesterol-lowering drug that induces LQTS, disrupted IKr trafficking and prolonged the cardiac action potential duration. Probucol did not directly block IKr. Probucol also disrupted hERG trafficking and did not block hERG channels expressed in human embryonic kidney 293 cells. We conclude that probucol induces LQTS by disrupting ether-a-go-go-related gene trafficking, and that primary culture of neonatal rat cardiomyocytes represents a useful system for studying native IKr trafficking.
VeRA - Version Number and Rank Authentication in RPL

Designing a routing protocol for large low-power and lossy networks (LLNs), consisting of thousands of constrained nodes and unreliable links, presents new challenges. The IPv6 Routing Protocol for Low-power and Lossy Networks (RPL), have been developed by the IETF ROLL Working Group as a preferred routing protocol to provide IPv6 routing functionality in LLNs. RPL provides path diversity by building and maintaining directed acyclic graphs (DAG) rooted at one (or more) gateway. However, an adversary that impersonates a gateway or has compromised one of the nodes close to the gateway can divert a large part of network traffic forward itself and/or exhaust the nodes' batteries. Therefore in RPL, special security care must be taken when the Destination Oriented Directed Acyclic Graph (DODAG) root is updating the Version Number by which reconstruction of the routing topology can be initiated. The same care also must be taken to prevent an internal attacker (compromised DODAG node) to publish decreased Rank value, which causes a large part of the DODAG to connect to the DODAG root via the attacker and give it the ability to eavesdrop a large part of the network traffic forward itself. Unfortunately, the currently available security services in RPL will not protect against a compromised internal node that can construct and disseminate fake messages. In this paper, a new security service is described that prevents any misbehaving node from illegitimately increasing the Version Number and compromise illegitimate decreased Rank values.
Implementation of Monitoring and Information Service Using Ganglia and NWS for Grid Resource Brokers

Grid computing is increasingly used by organizations to achieve high performance computing and heterogeneous resources sharing. These grids may span several domain administrations via Internet. As a result of this, it may be difficult to monitor, control and manage those machines and resources. This paper aims at providing a multi-platform grid monitoring service which can monitor resources such as CPU speed and utilization, memory usage, disk usage, and network bandwidth in a real-time manner. Monitoring data is extracted form Ganglia and NWS tools then stored and transmitted in XML form and then used for displaying. All the information is displayed using real-time graphs.
ANÁLISE DO COMPORTAMENTO DO CONSUMIDOR NA DECISÃO DE COMPRA DE SUCOS: UM ESTUDO NA REGIÃO SUL DO BRASIL

O objetivo deste estudo e analisar o comportamento do consumidor, verificando se as estrategias de marketing estao alinhadas ao perfil do consumidor e ao planejamento de marketing. Para chegar ao objetivo planejado, realizou-se uma coleta de dados baseando-se em pesquisa de campo, com uma amostra de 405 consumidores, alem da investigacao do publico-alvo do segmento de sucos de uma empresa multinacional. Os resultados encontrados apontam que algumas estrategias estao alinhadas com o perfil do consumidor, porem ha necessidade da revisao de algumas praticas, devido a analise do comportamento do consumidor, em que algumas acoes podem ser tomadas, a fim de melhorar a percepcao dos consumidores e compradores em relacao a promocao do produto.
Descending inputs to the caudal cochlear nucleus of the cat: Degeneration and autoradiographic studies

Descending paths from the inferior colliculus (IC) and dorsal (DNLL) and ventral (VNLL) nuclei of the lateral lemniscus and their terminations in the caudal cochlear nucleus in cats were studied both in silver degeneration material following central lesions and in autoradiographs following central injections of tritiated leucine (3H‐leu). Eight adult cats received electrolytic lesions of the IC, the IC and DNLL, or the IC, DNLL and VNLL. Control cats were subjected either to surgery alone or to a lesion in a non‐auditory nucleus. After survival periods of 1 to 16 days, all cats were killed and their brain stems prepared by modified Nauta methods. Twenty‐two other cats received injections of 3H‐leu into the dorsal IC, the ventral IC and DNLL, or the DNLL and VNLL. Their brains were prepared for LM autoradiography. After lesions of the IC, Nauta material contained moderate degeneration of fine fibers that coursed predominantly in the lateral lemniscus, and partially decussated in the caudal trapezoid body to enter the cochlear nuclei of both sides. Sparse, mainly peridendritic degeneration of fine fibers occurred in the PVCN, while moderate, peridendritic and perisomatic degeneration occurred in the deep and innermost fusiform cell layers of the dorsal cochlear nucleus (DCN). Lesions of both the ventral IC and the DNLL showed additional bilateral degeneration of medium‐caliber axons in the descending tracts as well as preterminal degeneration of these larger axons sparsely distributed in the deep layers of the DCN. The density of medium‐caliber axonal degeneration (particularly in the deep DCN) increased when lesions also included the VNLL. After 3H‐leu injections into the tectum and/or upper pons, autoradiographs confirmed the presence of sparse bilateral inputs from both the IC and from the DNLL and VNLL to ventral cochlear nucleus neurons, including some octopus cell dendrites. The autoradiographic studies also clearly revealed a predominant input to the outer layer of the DCN from the dorsal IC, a predominant input to the middle layer from the ventral IC, and a predominant input to the deeper DCN from the lateral lemniscal nuclei. Limited evidence of a topographic, perhaps tonotopic, order within the descending connections was best seen in Nauta material. The differences shown here in fiber types, trajectories, and target sites from the IC, the DNLL, and the VNLL are discussed in terms of possible functional differences among the descending influences on neurons of the caudal cochlear nucleus.
Sildenafil normalizes bowel transit in preclinical models of constipation

Guanylyl cyclase-C (GC-C) agonists increase cGMP levels in the intestinal epithelium to promote secretion. This process underlies the utility of exogenous GC-C agonists such as linaclotide for the treatment of chronic idiopathic constipation (CIC) and irritable bowel syndrome with constipation (IBS-C). Because GC-C agonists have limited use in pediatric patients, there is a need for alternative cGMP-elevating agents that are effective in the intestine. The present study aimed to determine whether the PDE-5 inhibitor sildenafil has similar effects as linaclotide on preclinical models of constipation. Oral administration of sildenafil caused increased cGMP levels in mouse intestinal epithelium demonstrating that blocking cGMP-breakdown is an alternative approach to increase cGMP in the gut. Both linaclotide and sildenafil reduced proliferation and increased differentiation in colon mucosa, indicating common target pathways. The homeostatic effects of cGMP required gut turnover since maximal effects were observed after 3 days of treatment. Neither linaclotide nor sildenafil treatment affected intestinal transit or water content of fecal pellets in healthy mice. To test the effectiveness of cGMP elevation in a functional motility disorder model, mice were treated with dextran sulfate sodium (DSS) to induce colitis and were allowed to recover for several weeks. The recovered animals exhibited slower transit, but increased fecal water content. An acute dose of sildenafil was able to normalize transit and fecal water content in the DSS-recovery animal model, and also in loperamide-induced constipation. The higher fecal water content in the recovered animals was due to a compromised epithelial barrier, which was normalized by sildenafil treatment. Taken together our results show that sildenafil can have similar effects as linaclotide on the intestine, and may have therapeutic benefit to patients with CIC, IBS-C, and post-infectious IBS.
Temperature-dependent shifts in phenology contribute to the success of exotic species with climate change.

PREMISE OF THE STUDY The study of how phenology may contribute to the assembly of plant communities has a long history in ecology. Climate change has brought renewed interest in this area, with many studies examining how phenology may contribute to the success of exotic species. In particular, there is increasing evidence that exotic species occupy unique phenological niches and track climate change more closely than native species. METHODS Here, we use long-term records of species’ first flowering dates from fi ve northern hemisphere temperate sites (Chinnor, UK and in the United States, Concord, Massachusetts; Fargo, North Dakota; Konza Prairie, Kansas; and Washington,D.C.) to examine whether invaders have distinct phenologies. Using a broad phylogenetic framework, we tested for differences between exotic and native species in mean annual flowering time, phenological changes in response to temperature and precipitation,and longer-term shifts in first flowering dates during recent pronounced climate change (“flowering time shifts”). KEY RESULTS Across North American sites, exotic species have shifted flowering with climate change while native species, on average, have not. In the three mesic systems, exotic species exhibited higher tracking of interannual variation in temperature,such that flowering advances more with warming, than native species. Across the two grassland systems, however, exotic species differed from native species primarily in responses to precipitation and soil moisture, not temperature. CONCLUSIONS Our findings provide cross-site support for the role of phenology and climate change in explaining species’ invasions.Further, they support recent evidence that exotic species may be important drivers of extended growing seasons observed with climate change in North America.
Improved alkaline stabilization of municipal wastewater sludge.

In Mexico, physicochemical sludge contains high levels of pathogens; and alkaline stabilization is an alternative for their control. However, the odours caused mainly by ammonia generation represent a disadvantage. On the other hand, the ammonia is known as an effective disinfectant. The aim of this study was to evaluate the disinfectant properties of ammonia in sludge, and use it in a closed alkaline stabilization system, which, not only copes with odours but also increases the efficiency of the process. Raw sludge from a municipal wastewater treatment plant using a physicochemical process was used. Ammonia was applied in doses from 10 to 50% w/w; also, doses from 5 to 40% of CaO were applied in open and closed systems and raw and treated sludge quality was evaluated. Results showed that ammonia removed 6 and 5 logs of faecal coliforms and Salmonella spp. , respectively and up to 94% of viable helminth ova. The closed system was more efficient than the open system when applying doses from 5 to 20% of CaO. Finally, the results indicate that the ammonia represents an alternative to disinfecting wastewater sludge and it can be used to enhance alkaline stabilization processes.
Super-continuum generation in femtosecond erbium-doped fiber laser

Super-continuum light (1050–1700nm at the 75-dB level) was generated from femtosecond pulse of a mode-locked Er-doped fiber laser system. The system included the oscillator, Er-doped fiber amplifier (EDFA) and the spectral broadening system. A new type of fiber with an amplification of 10dB/km was applied in EDFA. The output pulse energy after amplification was 2.85 nJ with average power of 350 mW. This source with octave-spanning spectrum should find widespread applications in frequency metrology and spectroscopy.
An Optimization Approach to Joint Cell and Power Allocation in Multicell Networks

Since the seminal paper by Knopp and Humblet that showed that the system throughput of a single cell system is maximized if only one terminal transmits at a time, there has been a large interest in opportunistic communications and its relation to various fairness measures. On the other hand, in multicell systems there is a need to allocate transmission power such that some overall utility function is maximized typically under fairness constraints. Furthermore, in multicell systems the degree of resource allocation freedom includes the serving cell selection that allows for load balancing and thereby the efficient use of radio resources. In this paper we formulate the joint serving cell selection (link selection) and power allocation problem as an optimization task whose purpose is to maximize either the minimum user throughput or the multicell sum throughput. Both the max-min and the max-throughput problems are non-polynomial hard and we therefore propose heuristic solution approaches. We present numerical results that give new and valuable insights into the trade off between fair and sum throughput optimal joint resource allocation strategies.
Impact of Depression and Inflammation on the Progression of HIV Disease

The human immunodeficiency virus type 1 (HIV-1) epidemic has negatively affected over 40 million people worldwide. Antiretroviral therapy (ART) has improved life expectancy and changed the outcome of HIV-1 infection, making it a chronic and manageable disease. However, AIDS and non-AIDS comorbid illnesses persist during the course of infection despite the use of ART. In addition, the development of neuropsychiatric comorbidities (including depression) by HIV-infected subjects significantly affects quality of life, medication adherence, and disease prognosis. The factors associated with depression during HIV-1 infection include altered immune response, the release of pro-inflammatory cytokines, and monoamine imbalance. Elevated plasma pro-inflammatory cytokine levels contribute to the development of depression and depressive-like behaviors in HIV+ subjects. In addition, comorbid depression influences the decline rates of CD4+ cell counts and increases plasma viral load. Depression can manifest in some subjects despite their adherence to ART. In addition, psychosocial factors related to stigma (negative attitudes, moral issues, and abuse of HIV+ subjects) are also associated with depression. Both neurobiological and psychosocial factors are important considerations for the effective clinical management of HIV and the prevention of HIV disease progression.
North-South Differentiation and a Region of High Diversity in European Wolves (Canis lupus)

European wolves (Canis lupus) show population genetic structure in the absence of geographic barriers, and across relatively short distances for this highly mobile species. Additional information on the location of and divergence between population clusters is required, particularly because wolves are currently recolonizing parts of Europe. We evaluated genetic structure in 177 wolves from 11 countries using over 67K single nucleotide polymorphism (SNP) loci. The results supported previous findings of an isolated Italian population with lower genetic diversity than that observed across other areas of Europe. Wolves from the remaining countries were primarily structured in a north-south axis, with Croatia, Bulgaria, and Greece (Dinaric-Balkan) differentiated from northcentral wolves that included individuals from Finland, Latvia, Belarus, Poland and Russia. Carpathian Mountain wolves in central Europe had genotypes intermediate between those identified in northcentral Europe and the Dinaric-Balkan cluster. Overall, individual genotypes from northcentral Europe suggested high levels of admixture. We observed high diversity within Belarus, with wolves from western and northern Belarus representing the two most differentiated groups within northcentral Europe. Our results support the presence of at least three major clusters (Italy, Carpathians, Dinaric-Balkan) in southern and central Europe. Individuals from Croatia also appeared differentiated from wolves in Greece and Bulgaria. Expansion from glacial refugia, adaptation to local environments, and human-related factors such as landscape fragmentation and frequent killing of wolves in some areas may have contributed to the observed patterns. Our findings can help inform conservation management of these apex predators and the ecosystems of which they are part.
Triple-loop learning : theoretical framework, methodology & illustration

L’apprentissage en triple boucle : cadre theorique, methodologie et illustration a partir d’un exemple issu du secteur ferroviaireLe concept d’apprentissage organisationnel permet de determiner les modes de coordination entre les individus. Si la litterature est abondante concernant l’apprentissage en simple et double boucle, il semble que l’apprentissage en triple boucle fasse l’objet d’une plus grande confidentialite. Or c’est precisement la mobilisation de ce dernier qui peut aboutir a la formation de nouvelles strategies d’apprentissage. Celles-ci favorisent la resolution de situations problematiques percues comme complexes, ameliorant ainsi la performance des organisations. Le present article propose, par une approche multi-methodologique innovante et la description d’un objet de recherche, de faciliter l’emergence de l’apprentissage en triple boucle.
The Evolving Faint End of the Luminosity Function

We investigate the evolution of the faint-end slope of the luminosity function, α, using semianalytical modeling of galaxy formation. In agreement with observations, we find that the slope can be fitted well by α(z) = a + bz, with a = -1.13 and b = -0.1. The main driver for the evolution in α is the evolution in the underlying dark matter mass function. Sub-L* galaxies reside in dark matter halos that occupy a different part of the mass function. This part of the mass function is steeper at high redshifts than at low redshifts, and hence α is steeper. Supernova feedback in general causes the same relative flattening with respect to the dark matter mass function. The faint-end slope at low redshifts is dominated by field galaxies, and at high redshifts by cluster galaxies. The evolution of α(z) in each of these environments is different, with field galaxies having a slope b = -0.14 and cluster galaxies having a slope b = -0.05. The transition from a cluster-dominated to a field-dominated faint-end slope occurs roughly at a redshift z* ≃ 2 and suggests that a single linear fit to the overall evolution of α(z) might not be appropriate. Furthermore, this result indicates that tidal disruption of dwarf galaxies in clusters cannot play a significant role in explaining the evolution of α(z) at z < z*. In addition, we find that different star formation efficiencies a* in the Schmidt-Kennicutt law and supernova-feedback efficiencies ϵ generally do not strongly influence the evolution of α(z).