Miracle-dz/UniFAR-FTUs huggingface dataset:
The Efficacy of Live Virtual Machine Migrations Over the Internet

This paper describes a technique to enable live migration of virtual machines over the Internet. The method assumes the network supports Mobile IPv6 and that participating host devices support Xen 3.1. Unlike live migration schemes proposed by other researchers, virtual networks are not required. We describe our work in progress on developing a system that utilizes Mobile IPv6 to enable constant network connectivity through the migration. We identify the sources of delay associated with the live migration and conclude that as long as migrations occur relatively infrequently, live migration over the Internet is practical.
DFT and X-ray study of structural, electronic, elastic and optical properties in BE1–XZNXS alloys depending on Vegard’s law

Structural, optical and electronic properties and elastic constants of Be 1–x Zn x S alloys have been studied by employing the commercial code Castep based on density functional theory. The generalized gradient approximation and local density approximation were utilized as exchange correlation. Using elastic constants for compounds, bulk modulus, band gap, Fermi energy and Kramers–Kronig relations, dielectric constants and the refractive index have been found through calculations. Apart from these, X-ray measurements revealed elastic constants and Vegard’s law. It is seen that results obtained from theory and experiments are all in agreement.
Understanding Cardiomyopathy Phenotypes Based on the Functional Impact of Mutations in the Myosin Motor

Hypertrophic (HCM) and dilated (DCM) cardiomyopathies are inherited diseases with a high incidence of death due to electric abnormalities or outflow tract obstruction. In many of the families afflicted with either disease, causative mutations have been identified in various sarcomeric proteins. In this review, we focus on mutations in the cardiac muscle molecular motor, myosin, and its associated light chains. Despite the >300 identified mutations, there is still no clear understanding of how these mutations within the same myosin molecule can lead to the dramatically different clinical phenotypes associated with HCM and DCM. Localizing mutations within myosin's molecular structure provides insight into the potential consequence of these perturbations to key functional domains of the motor. Review of biochemical and biophysical data that characterize the functional capacities of these mutant myosins suggests that mutant myosins with enhanced contractility lead to HCM, whereas those displaying reduced contractility lead to DCM. With gain and loss of function potentially being the primary consequence of a specific mutation, how these functional changes trigger the hypertrophic response and lead to the distinct HCM and DCM phenotypes will be the future investigative challenge.
Parentage testing of Thoroughbred horse in Korea using microsatellite DNA typing

The present study was to construct a parentage testing system for Thoroughbred (TB) horse. A total number of 1,285 TB horse samples including 962 foals for parentage testing, 9 sires and 314 dams for individual identification were genotyped. Genomic DNA was extracted from 5 hair roots and genotyped by using 14 microsatellite markers (AHT4, AHT5, ASB2, ASB17, ASB23, CA425, HMS1, HMS3, HMS6, HMS7, HTG4, HTG10, LEX3 and VHL20). This method consisted of multiplexing PCR procedure and showed reasonable amplification of all PCR products. Genotypes were determined by genetic analyzer. The number of alleles per locus varied from 3 to 9 with a mean value of 6.36 in TB horse. The expected heterozygosity was ranged from 0.548 to 0.831 (mean 0.699), and the total exclusion probability of 14 microstellite loci was 0.9998. Of the 14 markers, ASB2, ASB17, ASB23, HMS7 and HTG10 loci have relatively high PIC value (> 0.7). Of the 962 foals, 960 foals were qualified by compatibility according to the Mendelism. These results suggest that the DNA typing method has high potential for parentage verification and individual identification of TB horses.
Bone Repair Using a Hybrid Scaffold of Self-Assembling Peptide PuraMatrix and Polyetheretherketone Cage in Rats

Self-assembling peptide scaffold (SAPS) is well known to have very good bone conduction properties. However, the intensity of SAPS is too weak to actually use it for a clinical bone regeneration. Therefore, we have produced a hybrid scaffold system that involves fabricating a cage from polyetheretherketone (PEEK) that has high intensity, filling the interior of this cage with SAPS, and then transplanted this hybrid scaffold to bone defects in rat femurs. After 28 days, soft X-ray radiographs and histological assessment revealed that good new bone formation was clearly observed in the defects transplanted the PEEK cage with SAPS, but not in the PEEK cage only. The PEEK cage maintained a form and osteoconduction ability of internal SAPS, and SAPS promoted bone formation inside the PEEK; therefore, each was in charge of intensity and bone regeneration separately. The present study suggests that hybrid scaffolds made from PEEK cages and SAPS can be useful tools for the regeneration of load-bearing bones, based on the idea that it should be possible to develop ideal bone filler materials by combining the strength of artificial bone with the bone regeneration and bone conduction properties of SAPS.
Cognitive Therapies: An Early Appraisal

Cognitive therapy embraces the theory and practice of a number of skilled and productive clinicians and researchers, and is being used increasingly. This essay has explained the core idea behind cognitive therapy, differentiated it from other standard forms of therapy, supplied some clinical examples, and attempted an early evaluation. The cognitive therapy idea is in its ascendency, and a more definitive evaluation will be possible only some years hence.
Monkey Frequency-Modulation Encoding in the Primary Auditory Cortex of the Awake Owl

[PDF] [Full Text] [Abstract] , September 26, 2007; 27 (39): 10372-10382. J. Neurosci. M. Elhilali, J. B. Fritz, T. -S. Chi and S. A. Shamma Auditory Cortical Receptive Fields: Stable Entities with Plastic Abilities [PDF] [Full Text] [Abstract] , October 1, 2007; 98 (4): 2337-2346. J Neurophysiol J. B. Fritz, M. Elhilali and S. A. Shamma Adaptive Changes in Cortical Receptive Fields Induced by Attention to Complex Sounds [PDF] [Full Text] [Abstract] , October 1, 2007; 98 (4): 2182-2195. J Neurophysiol C. A. Atencio, D. T. Blake, F. Strata, S. W. Cheung, M. M. Merzenich and C. E. Schreiner Monkey Frequency-Modulation Encoding in the Primary Auditory Cortex of the Awake Owl [PDF] [Full Text] [Abstract] , December 1, 2007; 98 (6): 3473-3485. J Neurophysiol H. Luo, Y. Wang, D. Poeppel and J. Z. Simon Cortex: Encoding Transition Concurrent Encoding of Frequency and Amplitude Modulation in Human Auditory [PDF] [Full Text] [Abstract] , January 9, 2008; 28 (2): 446-455. J. Neurosci. G. B. Christianson, M. Sahani and J. F. Linden Receptive Fields The Consequences of Response Nonlinearities for Interpretation of Spectrotemporal
Reversal of Interlaminar Signal Between Sensory and Memory Processing in Monkey Temporal Cortex

Feed-forward signals flowing across cortical layers during sensory coding reverse direction during memory retrieval. The primate temporal cortex implements visual long-term memory. However, how its interlaminar circuitry executes cognitive computations is poorly understood. Using linear-array multicontact electrodes, we simultaneously recorded unit activities across cortical layers in the perirhinal cortex of macaques performing a pair-association memory task. Cortical layers were estimated on the basis of current source density profiles with histological verifications, and the interlaminar signal flow was determined with cross-correlation analysis between spike trains. During the cue period, canonical “feed-forward” signals flowed from granular to supragranular layers and from supragranular to infragranular layers. During the delay period, however, the signal flow reversed to the “feed-back” direction: from infragranular to supragranular layers. This reversal of signal flow highlights how the temporal cortex differentially recruits its laminar circuits for sensory and mnemonic processing.
Measuring Skill in the Mutual Fund Industry

Using the value that a mutual fund extracts from capital markets as the measure of skill, we find that the average mutual fund has used this skill to generate about $3.2 million per year. Large cross-sectional differences in skill persist for as long as ten years. Investors recognize this skill and reward it by investing more capital with better funds. Better funds earn higher aggregate fees, and a strong positive correlation exists between current compensation and future performance. The cross-sectional distribution of managerial skill is predominantly reflected in the cross-sectional distribution of fund size, not gross alpha.
How to Break Access Control in a Controlled Manner

The electronic medical record (EMR) integrates heterogeneous information within a healthcare institution stressing the need for security and access control. The Biostatistics and Medical Informatics Department from Porto Faculty of Medicine has recently implemented a virtual EMR (VEMR) in order to integrate patient information and clinical reports within a university hospital. With more than 500 medical doctors using the system on a daily basis, an access control policy and model were implemented. However, the healthcare environment has unanticipated situations (i.e. emergency situations) where access to information is essential. Most traditional policies do not allow for overriding. A policy that allows for "Break-The-Glass (BTG)" was implemented in order to override access control whilst providing for non-repudiation mechanisms for its usage. The policy was easily integrated within the model confirming its modularity and the fact that user intervention in defining security procedures is crucial to its successful implementation and use
Telomere Length Dynamics and Chromosomal Instability in Cells Derived from Telomerase Null Mice

To study the effect of continued telomere shortening on chromosome stability, we have analyzed the telomere length of two individual chromosomes (chromosomes 2 and 11) in fibroblasts derived from wild-type mice and from mice lacking the mouse telomerase RNA (mTER) gene using quantitative fluorescence in situ hybridization. Telomere length at both chromosomes decreased with increasing generations of mTER−/− mice. At the 6th mouse generation, this telomere shortening resulted in significantly shorter chromosome 2 telomeres than the average telomere length of all chromosomes. Interestingly, the most frequent fusions found in mTER−/− cells were homologous fusions involving chromosome 2. Immortal cultures derived from the primary mTER−/− cells showed a dramatic accumulation of fusions and translocations, revealing that continued growth in the absence of telomerase is a potent inducer of chromosomal instability. Chromosomes 2 and 11 were frequently involved in these abnormalities suggesting that, in the absence of telomerase, chromosomal instability is determined in part by chromosome-specific telomere length. At various points during the growth of the immortal mTER−/− cells, telomere length was stabilized in a chromosome-specific man-ner. This telomere-maintenance in the absence of telomerase could provide the basis for the ability of mTER−/− cells to grow indefinitely and form tumors.
Role of viruses in the pathogenesis of IDDM.

Insulin-dependent diabetes mellitus (IDDM), also known as type I diabetes, results from the destruction of pancreatic beta cells. During the past few decades, genetic factors, autoimmunity and viral infections have been extensively studied as the possible cause of beta cell destruction. The evidence for virus-induced diabetes comes largely from experiments in animals, but several studies in humans also point to viruses as a trigger of this disease in some cases. There are at least two possible mechanisms for the involvement of viruses in the pathogenesis of IDDM: (a) cytolytic infection of beta cells may result in destruction of the cells without the induction of autoimmunity, or may be a final insult leading to the clinical onset of diabetes in individuals with an already decreased beta cell mass resulting from an autoimmune process; and (b) persistent viral infection (e.g. retrovirus, rubella virus, cytomegalovirus) may result in the triggering of autoimmune IDDM in certain circumstances. Regarding the latter possibility, viruses may insert, expose, or alter antigens in the plasma membrane of the beta cell, which may initiate autoimmunity leading to the destruction of the cells.
Introduction to Dental Materials

Section I Basic science for dental materials. Biomaterials, biocompatibility and biomechanics. A historical perspective. Atomic building blocks. Structure of ceramics. Structure of metal and alloys. Structure of polymers. Mechanical properties. Physical proerties. Chemical properties. Principles of adhesion. Section II Clinical dental materials. Dental amalgams. Resin composites and polyacid-modified resin composites. Glass-ionomer cements and resin-modified glass-ionomer cements. Intermdiate restorative materials. Enamel and dentine bonding. Endodontic materials. Impression materials. Section III Laboratory and related dental materials. Gypsum products. Denture base resins. Casting alloys for metallic restorations. Dental ceramics. Metal-bonded ceramics. Luting agents. Stainless steel.
METHODS OF FAMILY INCOME ESTIMATION IN THE TARGETING SOCIAL ASSISTANCE SYSTEM

Incomes as the main criterion of social stratification of a society not only determine its financial position, but also appreciably display a condition and efficiency of economy and economic relations in a society. In this paper the technique of an estimation of incomes of the family, basing on use of fuzzy logic is described. This approach allows to reflect in an estimation of family incomes model the incomplete and inexact information, the qualitative and quantitative data, criteria set and their weights, expert knowledge and gives an opportunity more adequately to reflect a real situation with a poverty level in each separately taken family. It is shown, that the made individual conclusions on families can be successfully applied for maintenance of decision-making support on an establishment of real applicants for reception of the targeting social assistance and definition of its size.
Use of grey relational analysis for multi-objective optimisation of NiTiCu shape memory alloy produced by powder metallurgy process

Powder metallurgy process was used in this work to produce NiTi specimens. Uniaxial compression, X-ray diffraction and differential scanning calorimetry were used for characterising the produced samples. L9 orthogonal arrays were chosen based on the Taguchi method for conducting the experiments. In order to optimise the processing parameters and also to determine the level of importance of each parameter, experiments were performed based on grey relational method. Our goal was to optimise recoverable strain (ε) and the finishing temperature of austenitic transformation (Af). Sintering time, compaction pressure, milling time and the atomic percentage of Cu were all selected as controllable parameters. Our results reveal that the sintering time and the atomic percentage of Cu are the most significant parameters. The findings were verified through a confirmatory test.
The impact of health on wages in Europe – does gender matter?

The impact of income and earnings on health has been well-examined in the literature while the impact of health on wages has been far less studied. Even rarer in previous work is the possible difference between the influences of health on wages for men versus women. As there is such a divergence between men and women in developed countries regarding both wages and health, studying the interaction of health and wages and how the relationship differs by gender is an important addition to our understanding of the complex relationship between health and labour market outcomes. The analysis draws on individual level data from up to eight waves of the European Community Household Panel (ECHP). Estimation procedures are applied to unbalanced panels from 14 different countries. The samples consist of employed adults aged 24 to 64 years. The data is used in estimation of Mincer-type wage functions where the natural logarithm of an individual’s hourly wage is function of a number of individual specific characteristics such as age, education, work experience, type of job, and health. Two health variables are included: self-assessed health status and an indicator of chronic illness or disability. The first estimates are obtained from pooled ordinary least squares. Further estimates are obtained from random effects and fixed effects panel models. A genderrelated difference in the association between health and wages has been found in several of the countries examined however; these differences are not the same in magnitude. For a number of countries, there appears to be no significant gender difference. Overall, self-assessed health has greater effects on men’s wages than women’s, while chronic illness appears to be more significant for women. The largest “gender-gap” seems to exist in France, Portugal, Spain and the United Kingdom.
Characterization of Smith-Waterman sequence database search in X10

Productivity and performance are always viewed as two sides of parallel programming languages. X10 is a new object-oriented parallel language for both high-productivity and high-performance. To help the development of X10, we characterize the performance of X10 in bioinformatics using the fundamental application Smith-Waterman (SW) sequence database search. We implement the SW application in X10 on multi-core shared-memory architecture. Through comparing with three SW implementations in C++, we make following suggestions for X10 as well as its compiler. (1) X10 compiler should improve its array access implementation in kernel loop to avoid redundant check and inefficient offset computation. The array access of the latest version X10 is much slower than that of C++, which results in poor single-core performance of SW in X10. (2) X10 should support the utilization of SIMD instructions. With 128-bit SSE instructions, SW in X10 can achieve 8.7--17.7 fold speedup. Note that there are many applications in the world which can dramatically benefit from SIMD architectures on modern processors.
Effects of Grain Size and Porosity on Electrical and Optical Properties of PLZT Ceramics

A group of transparent ferroelectric hot-pressed (Pb0.92La0.08)-(Zr0.65Ti0.35)0.98O3 specimens with controlled grain size and constant porosity and a group of similar specimens with controlled porosity and constant grain size were prepared. The electrical and optical constants and polarization-reversal properties of these ceramics were determined as functions of grain size and porosity. When poled PLZT ceramics were aged, the polarization-reversal characteristic was quite asymmetric, apparently because a space-charge field, E8p, was generated during aging. From a detailed study of the behavior of the E8p, including its (1) generation with increasing aging time, (2) relaxation with repeated polarization reversals, (3) relaxation by heat depolarization, and (4) grain-size and porosity dependence, it is concluded that the space-charge layer is present inside every domain. This layer also explains the grain-size dependencies of the remanent polarization, piezoelectric constants, and Curie point.
Some mathematical tools for the Lenski experiment

The Lenski experiment is a long term daily reproduction of Escherichia coli, that has evidenced phenotypic and genetic evolutions along the years. Some mathematical models, that could be usefull in understanding the results of that experiment, are reviewed here: stochastic and deterministic growth, mutation appearance and fixation, competition of species.
Bmc Medical Informatics and Decision Making Extensions to Decision Curve Analysis, a Novel Method for Evaluating Diagnostic Tests, Prediction Models and Molecular Markers

Background: Decision curve analysis is a novel method for evaluating diagnostic tests, prediction models and molecular markers. It combines the mathematical simplicity of accuracy measures, such as sensitivity and specificity, with the clinical applicability of decision analytic approaches. Most critically, decision curve analysis can be applied directly to a data set, and does not require the sort of external data on costs, benefits and preferences typically required by traditional decision analytic techniques.
The multiple viewpoints as approach to information retrieval within collaborative development context

Nowadays, to achieve competitive advantage, the industrial companies are considering that success is sustained to great product development. That is to manage the product throughout its entire lifecycle. Achieving this goal requires a tight collaboration between actors from a wide variety of domains, using different software tools producing various product data types and formats. The actors' collaboration is mainly based on the exchange /share product information. The representation of the actors' viewpoints is the underlying requirement of the collaborative product development. The multiple viewpoints approach was designed to provide an organizational framework following the actors' perspectives in the collaboration, and their relationships. The approach acknowledges the inevitability of multiple integration of product information as different views, promotes gathering of actors' interest, and encourages retrieved adequate information while providing support for integration through PLM and/or SCM collaboration. In this paper, a multiple viewpoints representation is proposed. The product, process, organization information models are discussed. A series of issues referring to the viewpoints representation are discussed in detail. Based on XML standard, taking electrical connector as an example, an application case of part of product information modeling is stated.
The generation characteristics of dielectric barrier glow discharge plasma in air

This paper focused on how to suppress filamentous discharge and achieve glow discharge in air. In this study, glow discharge plasma was generated under low pressure by the plate electrode using dielectric barrier. Pulse supply and sinusoidal supply were adopted in this study and their influence on glow discharge were analyzed. Discharge characteristics under different air gap between the electrodes were studied. In addition, we studied the influence of dielectric barrier conditions on the glow discharge. The results show, pulse discharge, shortening the discharge gap and suitable dielectric barrier conditions, can effectively prevent the occurrence of filamentous discharge which contributes to achieve the glow discharge in air.