Miracle-dz/UniFAR-FTUs huggingface dataset:
A Scoping Review of the Impact of COVID-19 on Kidney Transplant Patients in the United States

SARS-CoV-2, responsible for the COVID-19 pandemic, is a highly infectious virus that quickly became and continues to be a public health emergency, given the severe international implications. Immunocompromised patients, such as those undergoing kidney transplantation, are at an increased risk for severe illness from COVID-19 and require hospitalization for more aggressive treatment to ensure survival. COVID-19 has been infecting kidney transplant recipients (KTRs), affecting their treatment protocols, and threatening their survival. The objective of this scoping review was to summarize the published literature regarding the impact of COVID-19 on KTRs in the United States in terms of prevention, various treatment protocols, COVID-19 vaccination, and risk factors. The databases such as PubMed, MEDLINE/Ebsco, and Embase were used to search for peer-reviewed literature. The search was restricted to articles that were published on KTRs in the United States from January 1, 2019, to March 2022. The initial search yielded 1,023 articles after removing duplicates, leading to a final selection of 16 articles after screening with inclusion and exclusion criteria. Four domains emerged from the review: (1) impacts of COVID-19 on performing kidney transplants, (2) impacts of COVID-19 vaccinations on KTRs, (3) outcomes of treatment regiments for KTRs with COVID-19, and (4) risk factors associated with an increased mortality rate of COVID-19 in KTRs. Waitlisted patients for kidney transplants had a higher risk of mortality compared to nontransplant patients. COVID-19 vaccinations in KTRs are found to be safe, and the immune response can be improved by placing patients on a low dose of mycophenolate before vaccination. Withdrawal of immunosuppressants showed a mortality rate of 20% without increasing the rate of acute kidney injury (AKI). There is evidence to support that kidney transplantation with the accompanying immunosuppressant regimen can provide KTRs with better COVID-19 infection outcomes compared to waitlisted patients. Hospitalization, graft dysfunction, AKI, and respiratory failure were the most common risk factors that increased the risk of mortality in COVID-19-positive KTRs. Withdrawing KTRs from immunosuppressive drugs increased the mortality rate. Further studies are needed to investigate the effects of specific drugs and dosages on the severity and mortality rate of COVID-19 in KTRs.
An Empirical Investigation of Absorptive Capacity on Technology Transfer Effectiveness Through Organizational Innovation

Purpose: Achieving technology transfer effectiveness (TTE) remains challenging in developing and underdeveloped economies to improve social infrastructures and develop economic systems. Bringing effectiveness in technology transfer is a complicated process for organizations that require improvement in their absorptive capacity (ACAP) and organizational innovation (OI). In the Information and communication technology (ICT) sector of Pakistan, technology transfer is ineffective due to a lack of ACAP and OI. This study aims to investigate the impact of ACAP and OI on TTE in the ICT sector of Pakistan. Theoretical framework: This study empirically investigated the relationship of ACAP and OI with TTE with underpinning organizational learning theory. Design/methodology/approach: A cross-sectional survey design was adapted for collecting data from 393 management representatives from 33 organizations of two main sub-sectors (Telecommunications and Information Technology) of the ICT sector of Pakistan. PLS-SEM was used for the reliability and validity measurement of research constructs. It also tested the hypothesized relationships between ACAP, OI, and TTE. Findings: This study confirmed the significant relationship of ACAP and OI with TTE. Further, the results also confirmed the mediation of OI between ACAP and TTE in the ICT sector of Pakistan. Research, Practical & Social implications: The implication of this research is to help government institutions and public and private sectors to develop mechanisms, economic policies, strategies, and business support for effective technology transfer in the ICT sector. This research model is also helpful for researchers and practitioners in its applicability in other industries, countries, and cross-cultural environments. Originality/value: Due to the lack of research in the ICT sector of Pakistan, this study empirically investigated the hypothesized significant relationships of ACAP and OI with TTE. This study also filled the research gap by evaluating the significant mediation of OI between ACAP and TTE and contributed to the body of knowledge.
Recursive quantum spatial search does not need ancilla qubit

Spatial search is a widely studied application of quantum algorithms. Several algorithms have been proposed for spatial search without using ancilla qubits which are easier to implement physically. All such algorithms are based on the widely studied quantum walk approach. Here we consider another approach by Aaronson and Ambainis based on the recursive application of Grover's algorithm rather than quantum walks. Their algorithm needs one ancilla qubit for successful implementation. We present a different recursive algorithm which does not need any ancilla qubit and hence it offers physical implementation advantages.
Optical and other physical properties of semiconducting cadmium vanadate glasses

The optical and other physical properties of semiconducting xV2O5−(1−x)CdO glasses have been reported in this article. The changes in both density and molar volume indicate structural modification of crystalline V2O5 due to addition of CdO. The glass transition temperatures are observed to decrease with an increase in V2O5 content in the compositions. It has been observed from the analysis of Fourier-transform infrared spectra that the network structure strongly depends upon the V2O5 content in the glass compositions. Introduction of CdO into the V2O5 matrix changes the two-dimensional layer structure of the crystalline V2O5 into a more complicated three-dimensional structure. The fundamental absorption edge for all the glasses is analyzed in terms of the theory proposed by Davis and Mott [E. A. Davis and N. F. Mott, Philos. Mag. 22, 903 (1970)]. The position of absorption edge and, hence, the value of the optical band gap are found to depend on the V2O5 content in the glass compositions.
Adolescent binge ethanol impacts H3K36me3 regulation of synaptic genes

Adolescence is marked in part by the ongoing development of the prefrontal cortex (PFC). Binge ethanol use during this critical stage in neurodevelopment induces significant structural changes to the PFC, as well as cognitive and behavioral deficits that can last into adulthood. Previous studies showed that adolescent binge ethanol causes lasting deficits in working memory, decreases in the expression of chromatin remodeling genes responsible for the methylation of histone 3 lysine 36 (H3K36), and global decreases in H3K36 in the PFC. H3K36me3 is present within the coding region of actively-transcribed genes, and safeguards against aberrant, cryptic transcription by RNA Polymerase II. We hypothesize that altered methylation of H3K36 could play a role in adolescent binge ethanol-induced memory deficits. To investigate this at the molecular level, ethanol (4 g/kg, i.g.) or water was administered intermittently to adolescent mice. RNA-and ChIP-sequencing were then performed within the same tissue to determine gene expression changes and identify genes and loci where H3K36me3 was disrupted by ethanol. We further assessed ethanol-induced changes at the transcription level with differential exon-use and cryptic transcription analysis – a hallmark of decreased H3K36me3. Here, we found ethanol-induced changes to the gene expression and H3K36me3-regulation of synaptic-related genes in all our analyses. Notably, H3K36me3 was differentially trimethylated between ethanol and control conditions at synaptic-related genes, and Snap25 and Cplx1 showed evidence of cryptic transcription in males and females treated with ethanol during adolescence. Our results provide preliminary evidence that ethanol-induced changes to H3K36me3 during adolescent neurodevelopment may be linked to synaptic dysregulation at the transcriptional level, which may explain the reported ethanol-induced changes to PFC synaptic function.
Accelerations Recorded by Simple Inertial Measurement Units with Low Sampling Frequency Can Differentiate between Individuals with and without Knee Osteoarthritis: Implications for Remote Health Care

Determining the presence and severity of knee osteoarthritis (OA) is a valuable application of inertial measurement units (IMUs) in the remote monitoring of patients. This study aimed to employ the Fourier representation of IMU signals to differentiate between individuals with and without knee OA. We included 27 patients with unilateral knee osteoarthritis (15 females) and 18 healthy controls (11 females). Gait acceleration signals were recorded during overground walking. We obtained the frequency features of the signals using the Fourier transform. The logistic LASSO regression was employed on the frequency domain features as well as the participant’s age, sex, and BMI to distinguish between the acceleration data from individuals with and without knee OA. The model’s accuracy was estimated by 10-fold cross-validation. The frequency contents of the signals were different between the two groups. The average accuracy of the classification model using the frequency features was 0.91 ± 0.01. The distribution of the selected features in the final model differed between patients with different severity of knee OA. In this study, we demonstrated that using logistic LASSO regression on the Fourier representation of acceleration signals can accurately determine the presence of knee OA.
A MODIFICATION TO THE SCHRÖDINGER EQUATION FOR BROADER BANDWIDTH GRAVITY-CAPILLARY WAVES ON DEEP WATER WITH DEPTH-UNIFORM CURRENT

Abstract We derive a nonlinear Schrödinger equation for the propagation of the three-dimensional broader bandwidth gravity-capillary waves including the effect of depth-uniform current. In this derivation, the restriction of narrow bandwidth constraint is extended, so that this equation will be more appropriate for application to a realistic sea wave spectrum. From this equation, an instability condition is obtained and then instability regions in the perturbed wavenumber space for a uniform wave train are drawn, which are in good agreement with the exact numerical results. As it turns out, the corrections to the stability properties that occur at the fourth-order term arise from an interaction between the mean flow and the frequency-dispersion term. Since the frequency-dispersion term, in the absence of depth-uniform current, for pure capillary waves is of opposite sign for pure gravity waves, so too are the corrections to the instability properties.
Validating Healthy Eating Index, Glycemic Index, and Glycemic Load with Modern Diets for E-Health Era

Predictors of healthy eating parameters, including the Healthy Eating Index (HEI), Glycemic Index (GI), and Glycemic Load (GL), were examined using various modern diets (n = 131) in preparation for personalized nutrition in the e-health era. Using Nutrition Data Systems for Research computerized software and artificial intelligence machine-learning-based predictive validation analyses, we included domains of HEI, caloric source, and various diets as the potentially modifiable factors. HEI predictors included whole fruits and whole grains, and empty calories. Carbohydrates were the common predictor for both GI and GL, with total fruits and Mexican diets being additional predictors for GI. The median amount of carbohydrates to reach an acceptable GL < 20 was predicted as 33.95 g per meal (median: 3.59 meals daily) with a regression coefficient of 37.33 across all daily diets. Diets with greater carbohydrates and more meals needed to reach acceptable GL < 20 included smoothies, convenient diets, and liquids. Mexican diets were the common predictor for GI and carbohydrates per meal to reach acceptable GL < 20; with smoothies (12.04), high-school (5.75), fast-food (4.48), Korean (4.30), Chinese (3.93), and liquid diets (3.71) presenting a higher median number of meals. These findings could be used to manage diets for various populations in the precision-based e-health era.
Time-dependent studies of single and multiple photoionization of H2+

A time-dependent method is used to study the photoionization of the simplest one-electron molecule, H{sub 2}{sup +}. We use the variational principle to solve the time-dependent Schroedinger equation for H{sub 2}{sup +} in spherical coordinates (r,{theta}) centered on the center of mass of the H{sub 2}{sup +} system in a time-varying electromagnetic field, in the fixed-nuclei approximation. Bound and continuum states of H{sub 2}{sup +} are obtained by diagonalizing the two-dimensional Hamiltonian for H{sub 2}{sup +} on a uniform lattice. Two different algorithms for the time propagation of the Schroedinger equation are described, the first an explicit time propagator involving matrix multiplication and the second an implicit time propagator involving matrix inversion. Single-photoionization cross sections for H{sub 2}{sup +} are presented for the cases where the laser field is oriented both parallel and perpendicular to the internuclear axis. Excellent agreement is found between the present calculations and previous work. Two- and three-photon ionization cross sections are also presented for the cases where the laser field is oriented both parallel and perpendicular to the internuclear axis. Comparison with previous work is available only for the parallel orientation case where good agreement is found with a previous time-independent calculation.
Effect of male–female relatedness on aggression and inbreeding in an egg parasitoid wasp

Aggressive behavior is important for acquiring crucial resources in many animals. As such behavior is costly, selection favors contestants that can accurately gather information regarding the likely costs and benefits of conflict to enable appropriate tactical decisions. Mate choice based on relatedness is widespread among animals and has severe consequences. Theoretically, due to the potential costs of inbreeding, contestants may benefit from discriminating between relative and nonrelative mates and adjusting their behavior accordingly. If inbreeding results in fitness costs, related mates might be perceived as less valuable and individuals might be expected to invest less in costly aggression, and vice versa. However, the role of male–female relatedness in aggression has been less addressed. The egg parasitoid wasp Anastatus disparis, which exhibits extreme male–male aggressive behavior for mating opportunities, was used as an experimental model to explore the role of male–female relatedness in aggression. Inconsistent with our prediction, male–female relatedness had no significant effect on male–male fighting frequency or intensity in A. disparis. The ability of males to discriminate relative from nonrelative females is a prerequisite for male–female relatedness to affect males’ aggression. However, A. disparis males did not exhibit any mating preferences for relative or nonrelative females. Besides, inbreeding did not result in depression in terms of longevity, fecundity or sex ratio in A. disparis. Our finding of no effect of male–female relatedness on male–male fights in A. disparis may be caused by a lack of kin discrimination ability or/and a lack of benefits from discriminating relatives from nonrelatives.
The formation of waveguides and modulators in LiNbO3 by ion implantation

Ion implantation is an attractive method for writing optical circuits for use in integrated optics. In LiNbO3 it is shown that there are large changes produced in both refractive indices n0 and ne by the energy deposited in nuclear collisions between the implanted ions and the lattice. The process is insensitive to ion species and at 300 K a universal curve exists for the decrease of n0 as a function of deposited energy by nuclear collisions. Saturation changes of −6% occur at 300 °K, and larger values are noted for 77 K implants. The saturation condition is reached after the deposition of ∼1022 keV cm−3 from the ion beams. Because the indices are reduced, ion beams have been used to write low index boundaries to define waveguiding regions. By using energetic light ions (e.g., 2‐MeV He+) negligible change is produced in the surface layer where the energy loss is primarily electronic and thus the low index region is formed deep within the solid. The computed and measured mode characteristics are in good ag.
HAP1, a new revolutionary cell model for gene editing using CRISPR-Cas9

The use of next-generation sequencing (NGS) technologies has been instrumental in the characterization of the mutational landscape of complex human diseases like cancer. But despite the enormous rise in the identification of disease candidate genetic variants, their functionality is yet to be fully elucidated in order to have a clear implication in patient care. Haploid human cell models have become the tool of choice for functional gene studies, since they only contain one copy of the genome and can therefore show the unmasked phenotype of genetic variants. Over the past few years, the human near-haploid cell line HAP1 has widely been consolidated as one of the favorite cell line models for functional genetic studies. Its rapid turnover coupled with the fact that only one allele needs to be modified in order to express the subsequent desired phenotype has made this human cell line a valuable tool for gene editing by CRISPR-Cas9 technologies. This review examines the recent uses of the HAP1 cell line model in functional genetic studies and high-throughput genetic screens using the CRISPR-Cas9 system. It covers its use in an attempt to develop new and relevant disease models to further elucidate gene function, and create new ways to understand the genetic basis of human diseases. We will cover the advantages and potential of the use of CRISPR-Cas9 technology on HAP1 to easily and efficiently study the functional interpretation of gene function and human single-nucleotide genetic variants of unknown significance identified through NGS technologies, and its implications for changes in clinical practice and patient care.
Burkholderia gladioli strain KJ-34 exhibits broad-spectrum antifungal activity

Introduction Plant pathogens are one of the major constraints on worldwide food production. The antibiotic properties of microbes identified as effective in managing plant pathogens are well documented. Methods Here, we used antagonism experiments and untargeted metabolomics to isolate the potentially antifungal molecules produced by KJ-34. Results KJ-34 is a potential biocontrol bacterium isolated from the rhizosphere soil of rice and can fight multiple fungal pathogens (i.e. Ustilaginoidea virens, Alternaria solani, Fusarium oxysporum, Phytophthora capsica, Corynespora cassiicola). The favoured fermentation conditions are determined and the fermentation broth treatment can significantly inhibit the infection of Magnaporthe oryzae and Botryis cinerea. The fermentation broth suppression ratio is 75% and 82%, respectively. Fermentation broth treatment disrupted the spore germination and led to malformation of hyphae. Additionally, we found that the molecular weight of antifungal products were less than 1000 Da through semipermeable membranes on solid medium assay. To search the potentially antifungal molecules that produce by KJ-34, we used comparative and bioinformatics analyses of fermentation broth before and after optimization by mass spectrometry. Untargeted metabolomics analyses are presumed to have a library of antifungal agents including benzoylstaurosporine, morellin and scopolamine. Discussion These results suggest that KJ-34 produced various biological control agents to suppress multiple phytopathogenic fungi and showed a strong potential in the ecological technologies of prevention and protection.
LOCATION DETERMINATION IN URBAN ENVIRONMENT FROM IMAGE SEQUENCES

Abstract. Location Determination Problem (LDP) is a classic and interesting problem both for photogrammetry and computer vision community: Given an image depicting a set of landmarks with known locations, determine that point in space from which the image was obtained. In this paper we try to use image sequences to automatically solve LDP in local Euclidean space in which no georeference information is needed. Overlapping image sequences are preferable for matching images obtained in cities. We implement a method which can semi-automatically solve LDP in urban scenario with state-of-the-art 3D reconstruction system.
Distribution of the amount of genetic material from a chromosomal segment surviving to the following generation

A method is provided for numerical evaluation, with any given accuracy, of the probability that at least p% of the genetic material from an individual's chromosomal segment survives to the next generation. Relevant MAPLE® V codes, for automated implementation of such evaluation, are also provided. The genomic continuum model, with Haldane's model for the crossover process, is assumed.
Properties of the induced semigroup of an Archimedean copula

It is shown that to every Archimedean copula H there corresponds a one-parameter semigroup of transformations of the interval [0, 1]. If the elements of the semigroup are diffeomorphisms, then it determines a special function vH called the vector generator. Its knowledge permits finding a pseudoinverse y = h(x) of the additive generator of the Archimedean copula H by solving the differential equation dy/dx = vH(y)/x with initial condition (dh/dx)(0) = −1. Weak convergence of Archimedean copulas is characterized in terms of vector generators. A new characterization of Archimedean copulas is also given by using the notion of a projection of a copula.
New Insights on Ground Deformation at Campi Flegrei Caldera Inferred From Kinematics and Dynamics Investigation of Borehole Tilt

The study of the ground deformation in active calderas provides valuable indications of the ongoing dynamical processes. In this framework, we analyze the borehole tiltmeter data recorded at Campi Flegrei (Southern Italy) from their first installation (1 April 2015), in order to retrieve the kinematics of the ground deformation and its main anomalies. Our approach involves the nonlinear dynamics analysis aimed at the identification of the degrees of freedom of the system and thus its complexity. Starting from the second part of the year 2020, the behavior of the dynamical system becomes collective, and a locally significant deviation of the deformative pattern from the background trend is observed. In particular, a series of 15 slow tilt variations (like jumps lasting a few days) appears in the ground deformation. They are associated with a very low‐dimensional system likely generated by a local second‐order source. The latter is related to fluid migration and it is superimposed on the primary one located in Pozzuoli town and driving the current uplift of Campi Flegrei. The effects of such a local, second‐order stress field are, indeed, evident in the area of the volcanic dome of Mt. Olibano, where they are measured as tilt steps. The superposition of primary and second‐order sources of deformation acting contemporaneously can justify the recent variations in geophysical and geochemical parameters. Our approach based on the joint dynamical and kinematical analyses of the tiltmeter data can be applied to other volcanic/tectonic areas or extended to other geophysical and geochemical variables.