Miracle-dz/UniFAR-FTUs huggingface dataset:
A multi-study analysis enables identification of potential microbial features associated with skin aging signs

Introduction: During adulthood, the skin microbiota can be relatively stable if environmental conditions are also stable, yet physiological changes of the skin with age may affect the skin microbiome and its function. The microbiome is an important factor to consider in aging since it constitutes most of the genes that are expressed on the human body. However, severity of specific aging signs (one of the parameters used to measure “apparent” age) and skin surface quality (e.g., texture, hydration, pH, sebum, etc.) may not be indicative of chronological age. For example, older individuals can have young looking skin (young apparent age) and young individuals can be of older apparent age. Methods: Here we aim to identify microbial taxa of interest associated to skin quality/aging signs using a multi-study analysis of 13 microbiome datasets consisting of 16S rRNA amplicon sequence data and paired skin clinical data from the face. Results: We show that there is a negative relationship between microbiome diversity and transepidermal water loss, and a positive association between microbiome diversity and age. Aligned with a tight link between age and wrinkles, we report a global positive association between microbiome diversity and Crow’s feet wrinkles, but with this relationship varying significantly by sub-study. Finally, we identify taxa potentially associated with wrinkles, TEWL and corneometer measures. Discussion: These findings represent a key step towards understanding the implication of the skin microbiota in skin aging signs.
Orthogonal Tensor Recovery Based on Non-Convex Regularization and Rank Estimation

In this paper, a method for orthogonal tensor recovery based on non-convex regularization and rank estimation (OTRN-RE) is proposed, which aims to accurately recover the low-rank and sparse components of the tensor. Specifically, a new low-rank tensor decomposition algorithm is designed, which can efficiently establish the equivalence between the rank of a large tensor before decomposition and the rank of the coefficient tensor after decomposition. The large tensor is decomposed into a small standard orthogonal tensor and another coefficient tensor, and a generalized non-convex regularization is used to inscribe the low rank of the coefficient tensor. Meanwhile, a new rank estimation strategy is developed to dynamically adjust the size of small orthogonal tensors and coefficient tensors. Experimental results on image denoising and salient object detection tasks confirm the state-of-the-art performance of the proposed method in terms of denoising capability and computational speed.
Severe Hypertensive Response to Atropine Therapy for Bradycardia Associated with Dexmedetomidine: Case Report and Literature Review

Abstract Dexmedetomidine is a selective and potent α2-adrenoceptor agonist used for sedation, analgesia, and anxiolysis, with minimal respiratory depression; therefore, it is widely used in clinical practice. Transient hypertension has been reported to be an indication for the use of dexmedetomidine. The authors report three female patients who experienced hypertensive crisis when used atropine to treat bradycardia caused by dexmedetomidine. The transient hypertension is a relatively common side effect of dexmedetomidine, hypertensive crisis seen with coadministration of atropine is much less frequently reported. This is the first report to describe the use of atropine to treat bradycardia induced by dexmedetomidine, which may cause severe hypertension in female patients. They discuss the reason for and treatment of hypertension caused by administration of atropine and dexmedetomidine together and review the relevant literature.
Lasso Quantile Principal Component Regression

The classical regression model is very sensitive to econometrics problems, one this econometrics problem is Multicollinearity, to overcome this problem ,we will use two solutions: Firstly via using principal component regression and second solution via using quantile regression. When mix between these methods together give as robust model against the Multicollinearity problem. The simulation scenario and real data using in this study.
Laboratory Liquid-Jet X-ray Microscopy and X-ray Fluorescence Imaging for Biomedical Applications

Diffraction-limited resolution and low penetration depth are fundamental constraints in optical microscopy and in vivo imaging. Recently, liquid-jet X-ray technology has enabled the generation of X-rays with high-power intensities in laboratory settings. By allowing the observation of cellular processes in their natural state, liquid-jet soft X-ray microscopy (SXM) can provide morphological information on living cells without staining. Furthermore, X-ray fluorescence imaging (XFI) permits the tracking of contrast agents in vivo with high elemental specificity, going beyond attenuation contrast. In this study, we established a methodology to investigate nanoparticle (NP) interactions in vitro and in vivo, solely based on X-ray imaging. We employed soft (0.5 keV) and hard (24 keV) X-rays for cellular studies and preclinical evaluations, respectively. Our results demonstrated the possibility of localizing NPs in the intracellular environment via SXM and evaluating their biodistribution with in vivo multiplexed XFI. We envisage that laboratory liquid-jet X-ray technology will significantly contribute to advancing our understanding of biological systems in the field of nanomedical research.
Combining Nd isotopes in monazite and Hf isotopes in zircon to understand complex open-system processes in granitic magmas

Mapping the age and trace element and Sm-Nd isotope compositions of monazite grains from a peraluminous Cretaceous granite using laser ablation–split stream analysis reveals a wide range in Nd isotope and rare earth element (REE) compositions within and between single grains. These data corroborate isotopic variability indicated by Hf isotope analysis of zircon in the same granite sample. The REE variations indicate that monazite grew during fractional crystallization. Hf and Nd isotopes indicate that the granitic magma was generated from at least two distinct Proterozoic sources of approximately the same age: one component that had highly radiogenic initial 176Hf/177Hf and 143Nd/144Nd and a second component that was notably less radiogenic. This study highlights the utility of in situ REE and Sm-Nd isotope data in monazite in magmatic systems. Further, it refines the zircon-based constraints on magmatic processes because of sensitivity of light REEs to fractional crystallization, lower probability of complications owing to inheritance, and smaller analytical volumes required.
Modelling Approaches to Understand Salinity Variations in a Highly Dynamic Tidal River: The Case of the Shatt al-Arab River

The book reports the first systematic monitoring and modelling study on water availability, water quality and seawater intrusion of the Shatt al-Arab River (SAR) on the border of Iraq and Iran, where causes and concentration levels of salinity have not yet been fully understood, let alone addressed, leading to conflicting perceptions of its origin (external or internal), the natural conditions and the practices that can explain the current critical conditions. Current scientific knowledge on the SAR salinity problem is deficient, partially due to the complex and dynamic interaction between marine and terrestrial salinity sources, including return flows by water users of the different water sectors in the Euphrates and Tigris rivers upstream of the SAR. The development of a new series of monitoring stations and various modelling approaches helped to better understand the interactions between these different sources. The comprehensive and detailed dataset formed the basis for a validated analytical model that can predict the extent of seawater relative to other salinity sources in an estuary, and for a hydrodynamic model that can predict salinity changes. The adaptability of the models to changing conditions makes them directly applicable by water managers. The procedure can be applied to other comparable systems.
Ensuring Continuity of Care: Effective Strategies for the Post-hospitalization Transition of Psychiatric Patients in a Family Medicine Outpatient Clinic

In healthcare, continuity of care is a crucial element, especially for patients in the field of psychiatry who have recently been discharged from a hospital. The shift from inpatient to outpatient care poses challenges for patients and healthcare providers, including openness to treatment, competing priorities, financial insecurity, concerns and dilemmas faced by patients regarding their post-hospitalization life after improvements in symptoms, lack of social support, poor patient-doctor relationships, lack of insight, and stigma associated with mental illness. Therefore, it is vital to employ effective strategies to ensure patients receive the required care and support during this transition. This review delves into the significance of continuity of care for psychiatric patients post-hospitalization, effective strategies for the transition, and the challenges and barriers to implementation from the perspective of a family medicine practice. To analyze physicians' role in managing psychiatric patients post-hospitalization, we developed a comprehensive search strategy. This involved extracting relevant data, updates, guidelines, and recommendations. Our search spanned various online repositories, such as PubMed and Google Scholar, specifically focusing on US-based guidelines aligned with our objectives. The search was conducted using medical subject headings (MeSH) and combinations of "OR," "AND," and "WITH. " We crafted keywords to optimize our search strategy, including psychiatric illness, post-hospitalization, follow-up, follow-up care, primary care follow-up, and guidelines. Exploring online repositories yielded 132 articles, and we identified some guidelines that addressed our objectives. We established inclusion and exclusion criteria for our review and reviewed 21 papers. Post-hospitalization follow-up is a critical facet of psychiatric care, aligning with guidelines from the American Psychiatric Association and other relevant sources. Emphasizing continuity of care ensures a smooth transition from inpatient to outpatient settings, sustaining therapeutic momentum and minimizing the risk of relapse. This comprehensive approach involves careful medication management, regular mental health assessments, education on condition-specific coping strategies, and coordinated care between healthcare providers. It includes conducting risk assessments, safety planning, building social support and community integration, prompt post-hospitalization follow-up, and tailored treatment plans. Together, these measures enhance overall wellness for recently discharged patients. This holistic strategy tackles pressing short-term needs while facilitating long-term stability, promoting resilience and successful community reintegration, reducing readmission likelihood, and ultimately supporting sustained recovery.
Controlling foodborne pathogenic Citrobacter freundii via lytic bacteriophages

Recently, foodborne diseases caused by pathogenic bacteria have been expanding. This requires searching for ways to control or get rid of these diseases. Using bacteriophages to control, prevent and treatment of foodborne diseases is one of the important actions due to their killer effect on bacteria. Many species of pathogenic bacteria can be transmitted through food, including Citrobacter freundii which can cause food poisoning, urethritis, abscess, and meningitis in infants. This study aimed to isolate and characterize bacteriophages specific to Citrobacter freundii to be used to control the contamination of food with Citrobacter freundii . C. freundii and its specific bacteriophages were isolated from sewage water. Isolated phages were found to be belonging to two phage species. These two phages had a head and tail and were designated Citro 1 and Citro 2. Phage Citro 1 has a long contractile tail and Citro 2 has a long non-contractile tail. Therefore, they were classified into Family Myoviridae and Family Siphoviridae , respectively. Application of bacteriophages to green salad artificially contaminated with C. freundii resulted in a high reduction in the density of C. freundii in green salad kept at both room temperature and at 4°C. Moreover, when the density of C. freundii decreased the number of phage particles increased. Such results may indicate that bacteriophages can be used to control the contamination of foodstuffs with pathogenic bacteria.
The Relationship among Language Mindset, Corrective Feedback Preferences, and Follow-Up Strategies of Students in Writing Scientific Texts

Student learning success is primarily determined by their skills in writing scientific texts as their final assignment. However, students experience problems when preparing research proposals. The obstacles experienced were triggered by students' views that scientific writing is challenging and students' lack of understanding of input from lecturers. So, this research has four objectives, namely describing (a) language mindset, (b) corrective feedback preferences, (c) students' follow-up strategies in writing scientific texts, and (c) the correlation of the three. This research employed a mixed method. The research subjects were Indonesian Language Education students at the University of Muhammadiyah Malang. Data was collected using questionnaires and in-depth interviews. The results show that the highest average language mindset is a growth language mindset (4.573). As many as 95.3% of students had an average questionnaire of 3.5-5.00, so most students had a growth language mindset tendency. The dominant corrective feedback that students prefer is an explicit correction (4,895). The average of the follow-up strategy is 4.30, demonstrating that students try to receive corrective feedback on their written scientific texts from lecturers. Based on the correlation results, there is a significant relationship between language mindset and corrective feedback preference (0.529); there is a relationship between language mindset and follow-up strategy-based corrective feedback (0.297); but there is no significant relationship between corrective feedback preference and follow-up strategy based corrective feedback (0.160). The conclusion is that scientific text writing guidance activities need to encourage an increase in students' growth language mindset, corrective feedback preferences, and follow-up strategies in writing scientific text.
Eigenface and SIFT For Gender Classification

In this paper, we study and analyze five different approaches for gender classification (Male or Female). The purpose of approaches is to extract the main features from face image and for each approach; we used these features as input to the Support Vector Machine SVM classifier for classification process. In the first approach, we implemented the Principal Component Analysis PCA features as input to the SVM classifier. In the second approach, the resulted parameters of Scale Invariant Features Transform approach are used as input to SVM classifier. In the third approach, we implemented Eigenfaces as input to SIFT, and then the results of SIFT are used as input to SVM classifier also. In the fourth approach, we implemented Eigenfaces to be input to Volume-SIFT (VSIFT) and then used as input to SVM classifier. The last, we modified the VSIFT approach and use as input to SVM classifier. The practical implementation results show that the proposed approach (modified VSIFT) gave us high performance of gender classification than other approaches.The training and testing images set consist of number of faces which are obtained from (Computer Vision Science Research Projects). The aim of this paper is to analyze and discuss the results of applying the eigenfaces into the new proposed approach of modifying Volume-SIFT for classifying the faces into its gender.
An Analysis about Reinforcement Effect in Permafrost Preloading Region

Keywords: Permafrost region, Preloading, Freezing-thawing cycle, Settlement law Abstract. This study is based on an actual preloading project of permafrost region in Dalian, China. In order to obtain the testing results and reflect the reinforcement effect of this project, there are some preparations that are needed to be carried out, such as field monitoring, data analysis and so on. According to the testing results, the conclusion is obtained about that the physical and mechanical properties of the foundation after reinforcement and shear strength are significantly improved, the average degree of consolidation of the foundation reach more than 85%, and the effect of foundation reinforcement is more ideal. So it comes to a conclusion that it is feasible to use the preloading method to reinforce the soft soil foundation of permafrost region and it can provide a good reference to the similar projects.
Curious Case of Pediatric One-Lung Ventilation with Two Endotracheal Tubes: A Case Report

ABSTRACT One-lung ventilation is indicated during thoracic surgery for visualization and exposure of surgical site. It is achieved with bronchial blockers, double-lumen endobronchial tube, single-lumen endotracheal tubes and Univent tube for infants and children. Fibreoptic bronchoscope is required for placing and confirming the correct position of these tubes. We report a perioperative management of safe conduct of one lung ventilation for a 6-year child undergoing left lower lobe lobectomy through C-MAC video laryngoscope guided two single lumen tubes in limited resource settings where paediatric-sized fibreoptic bronchoscope is unavailable.
Methodology for estimating emissions from agriculture in the Netherlands – update 2018: calculations of CH4, NH3, N2O, NOx, PM10, PM2.5 and CO2 with the National Emission Model for Agriculture (NEMA)

The National Emission Model for Agriculture (NEMA) is used to calculate emissions to air from agricultural activities in the Netherlands on a national scale. Emissions of ammonia (NH3) and other N-compounds (NOx and N2O) are calculated from animal housing, manure storage, manure application and grazing using a Total Ammoniacal Nitrogen (TAN) flow model. Furthermore, emissions from application of inorganic N fertilizer, compost and sewage sludge, cultivation of organic soils, crop residues, and ripening of crops are calculated. NEMA is also used to estimate emissions of methane (CH4) from enteric fermentation and manure management, particulate matter (PM) from manure management and agricultural soils and carbon dioxide (CO2) from liming. Emissions are calculated in accordance with international guidance criteria and reported in an annual Informative Inventory Report (IIR; for air pollutants) and National Inventory Report (NIR; for greenhouse gases). This methodology report describes the outline and backgrounds of the emission calculations with NEMA.
Impact of bariatric surgery on maternal gestational weight gain and pregnancy outcomes in women with obesity: A population-based cohort study from Qatar

Background: Bariatric surgery is performed in obese women of reproductive age to help achieve a healthy prepregnancy weight to reduce the complications associated with obesity in pregnancy. However, these procedures can impact maternal nutrition and gestational weight gain (GWG). This study evaluates the maternal and neonatal outcomes in women with prepregnancy bariatric surgery and determines the impact on GWG.Methods: This study included 24 weeks gestation or more pregnancies, with a maternal BMI at delivery of 30 kg/m2 or more. It was categorized into two groups based on whether they had prepregnancy bariatric surgery (exposed) or not (unexposed). The outcomes included gestational diabetes (GDM), gestational hypertension (GHT), mode of delivery, preterm birth (PTB), GWG, birthweight (BW) and customized BW centiles, low birthweight (LBW), congenital anomalies, and admission to the neonatal intensive unit (NICU). Categorization was also done based on the adequacy of GWG (low, adequate, and excess). Results: A total of 8,323 women were included in the study, 194 of whom had prepregnancy bariatric surgery. After adjusting for confounders, the exposed group had a mean GWG 1.33 kg higher than the unexposed group (95% CI 0.55-2.13, p = 0.001). The exposed group had higher odds of PTB (aOR 1.78, 95% CI 1.16-2.74, p = 0.008), CD (aOR 6.52, 95% CI 4.28-9.93, p < 0.001), LBW in term babies (aOR 2.60, 95% CI 1.34-5.03, p = 0.005), congenital anomalies (aOR 2.64, 95% CI 1.21-5.77, p = 0.015), low APGAR score (aOR 3.75, 95% CI 1.12-12.5, p = 0.032) and 80.4g lesser birthweight (95% CI -153.0, -5.8; p = 0.034). More women in the low GWG category had LBW babies (28.6% versus 6.7% in the high GWG group, p = 0.033), lowest mean BW and median BW centiles (2775 grams versus 3289 grams in the high GWG group, p = 0.004 and 57.5% versus 74.5% in the high GWG group, p = 0.040, respectively). Conclusion: The findings of this study highlight differences in perinatal outcomes such as preterm birth, low birth weight, congenital anomalies, cesarean deliveries, and gestational weight gain between post-bariatric women and controls. These insights can help inform the planning and provision of appropriate maternity care to enhance patient safety and outcomes. The results of this study can also guide the counseling of reproductive age-group women who are planning to undergo bariatric surgery.
Cellular Strategies for Separating GvHD from GvL in Haploidentical Transplantation

GvHD still remains, despite the continuous improvement of transplantation platforms, a fearful complication of transplantation from allogeneic donors. Being able to separate GvHD from GvL represents the greatest challenge in the allogeneic transplant setting. This may be possible through continuous improvement of cell therapy techniques. In this review, current cell therapies are taken into consideration, which are based on the use of TCR alpha/beta depletion, CD45RA depletion, T regulatory cell enrichment, NK-cell-based immunotherapies, and suicide gene therapies in order to prevent GvHD and maximally amplify the GvL effect in the setting of haploidentical transplantation.
Radiomics prediction of response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer

Rectal cancer (RC) is one of the most common cancers worldwide. RC has high morbidity and mortality rates, with locally advanced rectal cancer (LARC) accounting for > 30% of cases. Patients with LARC are routinely treated with neoadjuvant chemoradiotherapy (nCRT) but treatment outcomes vary greatly. It is crucial to predict and evaluate patient response to nCRT as early as possible. Radiomics is a potentially useful and non-invasive tool for clinical applications in different types of cancer including colorectal cancer. Radiomics has recently been used to predict treatment outcomes and many published studies have demonstrated the efficacy of radiomics. This review will discuss the application of radiomics in predicting of LARC response to nCRT and provide new insight for corollary studies.