Miracle-dz/UniFAR-FTUs huggingface dataset:
Joint Sphere Detector and User Scheduling in Multiuser MIMO Uplink System

In this paper, we proposed a joint design scheme between sphere decoding and user scheduling for multiuser MIMO uplink system. This is a cross layer design scheme which adopt the channel quality information based on user scheduling to reduced the search radius of sphere detector, it leads the better bit error ratio performance and low complexity than conventional sphere detection with fixed search radius.
THE MECHANISM OF ACTION OF COLCHICINE

The majority of the colchicine-3H bound by tissue culture cells (KB or Hela) was found to be present as a noncovalent complex with a macromolecule which appears in the soluble fraction after homogenization. Similar binding was demonstrated in vitro and was confined to a component of the soluble fraction. The binding-equilibrium constant and the kinetic constants were essentially the same in vivo and in vitro. Bound radioactivity was reisolated and shown to be present in a molecule with the same chromatographic behavior and specific antimitotic activity as colchicine. In vitro assay of binding activity of a variety of cells and tissues showed a correlation with the presence of microtubules. High binding activity was given by dividing cells, mitotic apparatus, cilia, sperm tails, and brain tissue. Binding to extracts of slime mold or to purified muscle proteins was very low or undetectable. The binding site had a sedimentation constant of 6S and it is suggested that the protein is a subunit of microtubules.
Vertebrate Epidermal Cells Are Broad-Specificity Phagocytes That Clear Sensory Axon Debris

Cellular debris created by developmental processes or injury must be cleared by phagocytic cells to maintain and repair tissues. Cutaneous injuries damage not only epidermal cells but also the axonal endings of somatosensory (touch-sensing) neurons, which must be repaired to restore the sensory function of the skin. Phagocytosis of neuronal debris is usually performed by macrophages or other blood-derived professional phagocytes, but we have found that epidermal cells phagocytose somatosensory axon debris in zebrafish. Live imaging revealed that epidermal cells rapidly internalize debris into dynamic phosphatidylinositol 3-monophosphate-positive phagosomes that mature into phagolysosomes using a pathway similar to that of professional phagocytes. Epidermal cells phagocytosed not only somatosensory axon debris but also debris created by injury to other peripheral axons that were mislocalized to the skin, neighboring skin cells, and macrophages. Together, these results identify vertebrate epidermal cells as broad-specificity phagocytes that likely contribute to neural repair and wound healing.
Showing Their True Colors? How EU Flag Display Affects Perceptions of Party Elites’ European Attachment

Evidence suggests that incidental national flag exposure activates nationalistic feelings and that incidental exposure to the EU flag can affect citizen attachments to Europe. However, we know little about what inferences citizens make based on the EU flag when they see it displayed by parties in an electoral context. To test the expectation that this display affects citizens’ evaluations of party elites’ EU attachment, we conducted a large-scale experiment embedded in a Swedish survey in which respondents were exposed to communications from one of the two main Swedish parties, containing or not containing the image of the flag. We find that simple visual display does little to move perceptions. However, if citizens perceive that a particular party displayed the flag, then they are more likely to evaluate its party elites as more attached to Europe.
Alice Dreger, Autogynephilia, and the Misrepresentation of Trans Sexualities

1. Background: Blanchard’s sexual typology of trans women 3 2. Dreger neglects relevant issues faced by trans women 4 3. Social and cultural factors do not account for the clinical realities of gender dysphoria 5 4. Sexual explanations are insufficient to account for gender dysphoria 7 5. Blanchard’s typology requires accusing large numbers of trans women of deception or delusion 9 6. Autogynephilia is used as a stigmatizing label in personal disputes by sexologists and by Dreger 14 7. Other issues 17 8. Societal fallout from a sexualized theory of trans women’s genders 18
Pressure ulcer prevention and treatment: use of prophylactic dressings

: The management of pressure ulcers is challenging for health care providers across disciplines. Pressure ulcers have significant impact on emotional and physical wellbeing, quality of life, and health care costs. The use of wound dressings could be an important and cost-effective strategy in preventing pressure ulcers. The main types of dressings that are examined for this purpose in the literature are foam, hydrocolloid
Issues in Designing Joint Radio Resource Management for Heterogeneous Wireless Networks

Designing a good joint radio resource management (JRRM) is a major challenge in heterogeneous wireless networks. Many analytical as well as simulation models of heterogeneous wireless networks are not based on fairly realistic assumptions so that the research outputs may be less practical. We design a JRRM taking into consideration different features of component access technologies in a heterogeneous wireless environment. We also consider different important realistic features of access networks, such as asymmetry of their overlap and the variability of network resources according to traffic conditions. We use the network simulator (NS-2) to validate our design. The simulation results show that the blocking probability improves when different considerations are taken into account.
Human-Robot Interaction Final Report for DARPA/NSF Study on Human-Robot Interaction

As part of a DARPA/NSF Study on Human-Robot Interaction, an interdisciplinary workshop was conceived, which would allow roboticists to interact with psychologists, sociologists, cognitive scientists, communication experts and human-computer interaction specialists to discuss common interests in the field of Human-Robot Interaction, and to establish a dialogue across the disciplines for future collaborations. Over sixty representatives from academia, government and industry gathered together on the campus of California Polytechnic State University in San Luis Obispo, CA, on September 29 and 30, 2001, and the results of that meeting are presented in this Final Report. We include initial work that was done in preparation for the workshop, links to keynote and other presentations, and a summary of the findings, outcomes and recommendations that were generated by the participants. A brief overview of the findings of the study is included here:
Dynamic load distribution algorithm performance in heterogeneous distributed system for I/O- intensive task

The goal of load balancing is to assign to each node a number of tasks proportional to its performance. Many load balancers have been proposed that deal with applications with homogeneous tasks; but, applications with heterogeneous tasks have proven to be far more complex to handle. Load balancing techniques play a very important role in developing high-performance cluster computing platforms. Many load balancing polices achieve high system performance by increasing the utilization of CPU, memory, or a combination of CPU and memory. However, these load-balancing policies are less effective when the workload comprises of a large number of I/O-intensive tasks and I/O resources exhibit imbalanced load. The I/O intensive tasks running on a heterogeneous cluster needs effective usage of global I/O resources. We have proposed a load-balancing scheme based upon system heterogeneity and migrate I/O-intensive tasks to the fastest processor. The proposed load balancing scheme can minimizes the average slow down of all parallel jobs running on a cluster and reduces the average response time of the jobs.
Delta-IDDQ Testing of Resistive Short Defects

This paper addresses the efficiency of IDDQ and more specifically Delta- IDDQ testing when using a realistic short defect model that properly considers the relation between the resistance of the short and its detectability. The results clearly show that the Delta-IDDQ approach covers a large number of resistive shorts missed by conventional logic testing, requiring only a relatively small vector set. In addition a significant number of defects which are proven to be undetectable by logic testing but may deteriorate and result in reliability failures are detected. The Delta- IDDQ threshold and thus the equipment sensitivity is shown to be critical for the test quality. Furthermore, the validity of the traditional IDDQ fault models when considering resistive short defects is found to be limited. For instance, the use of the fault-free next-state function for sequential IDDQ fault simulation is shown to result in a wrong classification of some resistive short defects. This is the first systematic study of IDDQ testing of resistive short defects. The impact of the threshold on the defect coverage is quantified for the first time. Although the simulation results are based upon a 0.35mum technology, the results and methodology can be transferred to state-of-the-art and NanoTechnologies
Human Tumor Antigens and Cancer Immunotherapy

With the recent developments of adoptive T cell therapies and the use of new monoclonal antibodies against the immune checkpoints, immunotherapy is at a turning point. Key players for the success of these therapies are the cytolytic T lymphocytes, which are a subset of T cells able to recognize and kill tumor cells. Here, I review the nature of the antigenic peptides recognized by these T cells and the processes involved in their presentation. I discuss the importance of understanding how each antigenic peptide is processed in the context of immunotherapy and vaccine delivery.
A gene regulatory network for cell differentiation in caenorhabditis elegans

Biological development is a remarkably complex process. A single cell, in an appropriate environment, contains enough information to produce a wide variety of specialised cell types, whose spatial and temporal dynamics interact to form intricately detailed patterns and behaviour. Much of the complexity of a developing system lies in the dynamics of gene regulation that occur within each cell. We used a simple recurrent network to model the process of gene regulation and evolved systems that were able to generate the first four cell divisions of the C. elegans cell lineage tree with a high degree of accuracy.
How metonymic are metaphors

Metonymy and metaphor are assumed to form a continuum with fuzzy cases between these categories. The paper focuses on the intermediate notion of metonymy-based metaphor. Four sources which may give rise to metonymy-based metaphor are distinguished: (i) a common experiential basis of source and target domain, due to the relationships of correlation and complementarity, (ii) conversational implicature, illustrated in the areas of implicated result and causation, implicated possession, and implicated purpose and activity, (iii) the taxonomic structure of categories, (iv) cultural models, exemplified by way of our folk understanding of physical force, communication and language, and emotion and physiological reaction. (Gunter Radden)
Assessing the preservation of cytosine methylation in ancient DNA from five prehistoric Native American populations APPROVED BY SUPERVISING COMMITTEE :

for contributing skeletal remains or aDNA extracts from the Yukisma and Xaltocan sites for this study. I also thank my committee members, Deborah Bolnick and Anthony DiFiore, for their invaluable contributions to this work. Cytosine methylation of CpG dinucleotides is an important epigenetic mark that regulates gene expression in humans. While methylation patterns in extant populations have been widely studied, few studies have attempted to analyze methylation in ancient DNA. Indeed, it was only recently shown that methyl groups can be preserved in ancient DNA. However, it is unknown how often methylation patterns can be recovered from ancient samples with preserved nuclear DNA. If they are frequently preserved, it may ultimately be possible to infer patterns of gene activity at the population level in ancient times. In this study, I assessed the preservation of cytosine methylation in ancient DNA from the remains of 30 prehistoric Native Americans from California, Illinois, Kentucky, and Mexico. These samples were previously shown to contain endogenous mitochondrial and nuclear DNA. I analyzed the cytosine methylation states of CpG-rich retrotransposons, which are epigenetically inactivated by cytosine methylation in humans. Unmethylated cytosines were converted to uracils by treatment with sodium v bisulfite. Bisulfite products were pyrosequenced, and C-toT conversions at potentially methylated CpG dinucleotides were quantified. I found that cytosine methylation is readily recoverable from human remains with preserved nuclear DNA from various localities over the time depth tested (~6000 years). This study presents the first direct evidence of cytosine methylation in ancient human remains, and suggests that it may be possible to analyze patterns of gene activity in ancient populations.
Algorithms for the verification of the semantic relation between a compound and a given lexeme

Text mining on a lexical basis is quite well developed for the English language. In compounding languages, however, lexicalized words are often a combination of two or more semantic units. New words can be built easily by concatenating existing ones, without putting any white spaces in between. That poses a problem to existing search algorithms: Such compounds could be of high interest for a search request, but how can be examined whether a compound comprises a given lexeme? A string match can be considered as an indication, but does not prove semantic relation. The same problem is faced when using lexicon based approaches where signal words are defined as lexemes only and need to be identified in all forms of appearance, and hence also as component of a compound. This paper explores the characteristics of compounds and their constituent elements for German, and compares seven algorithms with regard to runtime and error rates. The results of this study are relevant to query analysis and term weighting approaches in information retrieval system design.
Retino‐cortical stimulus frequency‐dependent gamma coupling: evidence and functional implications of oscillatory potentials

Long‐range gamma band EEG oscillations mediate information transmission between distant brain regions. Gamma band‐based coupling may not be restricted to cortex‐to‐cortex communication but may include extracortical parts of the visual system. The retinogram and visual event‐related evoked potentials exhibit time‐locked, forward propagating oscillations that are candidates of gamma oscillatory coupling between the retina and the visual cortex. In this study, we tested if this gamma coupling is present as indicated by the coherence of gamma‐range (70–200 Hz) oscillatory potentials (OPs) recorded simultaneously from the retina and the primary visual cortex in freely moving, adult rats. We found significant retino‐cortical OP coherence in a wide range of stimulus duration (0.01–1000 msec), stimulus intensity (800–5000 mcd/mm2), interstimulus interval (10–400 msec), and stimulus frequency (0.25–25 Hz). However, at low stimulus frequencies, the OPs were time‐locked, flickering light at 25 Hz entrained continuous OP coherence (steady‐state response, SSR). Our results suggest that the retina and the visual cortex exhibit oscillatory coupling at high‐gamma frequency with precise time locking and synchronization of information transfer from the retina to the visual cortex, similar to cortico‐cortical gamma coupling. The temporal fusion of retino‐cortical gamma coherence at stimulus rates of theater movies may explain the mechanism of the visual illusion of continuity. How visual perception depends on early transformations of ascending sensory information is incompletely understood. By simultaneous measurement of flash‐evoked potentials in the retina and the visual cortex in awake, freely moving rats, we demonstrate for the first time that time‐locked gamma oscillatory potentials exhibit stable retino‐cortical synchrony across a wide range of stimulus parameters and that the temporal continuity of coherence changes with stimulus frequency according to the expected change in the visual illusion of continuity.
Blood Detection In IVUS Longitudinal Cuts Using AdaBoost With a Novel Feature Stability Criterion

Lumen volume variations is of great interest by the physicians given the more it increases with a treatment the less probability of infarction. In this paper we present a fast and efficient method to detect the lumen borders in longitudinal cuts of IVUS sequences using an AdaBoost classifier trained with several local features assuring their stability. We propose a criterion for feature selection based on stability leave-one-out cross validation. Results on the segmentation of 18 IVUS pullbacks show that the proposed procedure is fast and robust leading to 90% of time reduction with the same characterization performance.
A novel vertical handoff decision making algorithm across Heterogeneous Wireless Networks

Heterogeneous Wireless Networks communication is a combination of various heterogeneous networks. With their complementary characteristics, incorporation of these technologies in the same network in order to provide a full coverage to mobile users causes several challenges such as handover decision making and mobility management. A good handoff decision should avoid unnecessary handovers, which increase the computational network load. In this paper, we present a novel approach for Handover decision making in the context of heterogeneous wireless network. The aim of the proposed scheme is the selection of the most suitable radio access network for each application. Simulation results show that the proposed approach can guarantee QoS requirements and reduce the blocking probability of new and handoff calls.
Oriented Bounding Boxes Based on Multi-resolution Contours

The determination of intersection or contact points between objects in interference is not a simple task. It could be time-consuming in a computer application. Generally, some real time applications use sophisticated algorithms based on hierarchical structure to isolate the segments of contours of objects in interference, to finally compute locally the contact points. Therefore, we are interested in search for the best way of constructing hierarchical structures bounding objects that allows us to quickly isolate the contour of segments in interference. To achieve that, the bounding must be adapted and fitted to the segments of the objects contours. In this work, we formulate a method to represent, in hierarchic structure, oriented rectangle boxes involving segments of object contours defined by closed cubical B-splines curves. Each oriented box is computed in adapted and fitted form to the segments of the contour by using the second order statistical indicator on some elements of the segments of object contour in multi-resolution representation.
Tetracycline Inducible Gene Manipulation in Serotonergic Neurons

The serotonergic (5-HT) neuronal system has important and diverse physiological functions throughout development and adulthood. Its dysregulation during development or later in adulthood has been implicated in many neuropsychiatric disorders. Transgenic animal models designed to study the contribution of serotonergic susceptibility genes to a pathological phenotype should ideally allow to study candidate gene overexpression or gene knockout selectively in serotonergic neurons at any desired time during life. For this purpose, conditional expression systems such as the tet-system are preferable. Here, we generated a transactivator (tTA) mouse line (TPH2-tTA) that allows temporal and spatial control of tetracycline (Ptet) controlled transgene expression as well as gene deletion in 5-HT neurons. The tTA cDNA was inserted into a 196 kb PAC containing a genomic mouse Tph2 fragment (177 kb) by homologous recombination in E. coli. For functional analysis of Ptet-controlled transgene expression, TPH2-tTA mice were crossed to a Ptet-regulated lacZ reporter line (Ptet-nLacZ). In adult double-transgenic TPH2-tTA/Ptet-nLacZ mice, TPH2-tTA founder line L62-20 showed strong serotonergic β-galactosidase expression which could be completely suppressed with doxycycline (Dox). Furthermore, Ptet-regulated gene expression could be reversibly activated or inactivated when Dox was either withdrawn or added to the system. For functional analysis of Ptet-controlled, Cre-mediated gene deletion, TPH2-tTA mice (L62-20) were crossed to double transgenic Ptet-Cre/R26R reporter mice to generate TPH2-tTA/Ptet-Cre/R26R mice. Without Dox, 5-HT specific recombination started at E12.5. With permanent Dox administration, Ptet-controlled Cre-mediated recombination was absent. Dox withdrawal either postnatally or during adulthood induced efficient recombination in serotonergic neurons of all raphe nuclei, respectively. In the enteric nervous system, recombination could not be detected. We generated a transgenic mouse tTA line (TPH2-tTA) which allows both inducible and reversible transgene expression and inducible Cre-mediated gene deletion selectively in 5-HT neurons throughout life. This will allow precise delineation of serotonergic gene functions during development and adulthood.
Does Feeling Bad, Lead to Feeling Good? Arousal Patterns during Expressive Writing

Different psychotherapy theories describe process patterns of emotional arousal in contradictory ways. To control both treatment and therapist responsivity, this study sought to test dynamic patterns in the arousal of negative affect using a controlled experimental study of expressive writing. There were 261 participants (78% women; M = 21 years old; 56% White) who suffered unresolved traumas who were randomly assigned to an expressive writing task and asked to write about their deepest thoughts and feelings, or to a writing control. Participants wrote for 15 min on three consecutive days, completing the Positive Affect and Negative Affect Scale before and after each visit. Data across 6 time points were subjected to hierarchical linear modeling (HLM) and pattern analyses. Session-by-session (24 hr periods), the expressive writing group showed an overall linear decrease in negative affect (β = −2.273, p < .001). However, in pre- to post-session ratings (15 min periods), the expressive writing group also demonstrated increases in negative affect (β = 6.467, p < .001). Neither of these patterns were observed in the control group. Pattern analysis demonstrated 69.8% of cases in the expressive writing group perfectly or almost perfectly followed a predicted zig-zag pattern (p < .01). No control cases showed this pattern. Findings demonstrate how the habituation/inhibition hypothesis (“it gets easier as one gets over it”) and the meaning-making hypothesis (“it gets worse before it gets better”) can both be supported, each at different scopes of analysis. Implications clarify the role of emotional arousal in change.