Miracle-dz/UniFAR-FTUs huggingface dataset:
Description of Conyzicola nivalis sp. nov., isolated from glacial snow, and emended description of the genus Conyzicola and Conyzicola lurida.

A cold-tolerant, translucent, yellow-pigmented, Gram-stain-positive, non-motile, rod-shaped bacteria was isolated from snow of the Zadang Glacier on the Tibetan Plateau, PR China. 16S rRNA gene sequence similarity analysis indicated that the isolate was closely related to Conyzicola lurida KCTC 29231T and Leifsonia psychrotolerans DSM 22824T at a level of 97.72 and 97.49 %, respectively. Other close relatives had a 16S rRNA gene sequence similarity of less than 97 %. The major cell-wall amino acid was 2,4-diaminobutyric acid. The cell-wall sugars were rhamnose, ribose, glucose, galactose and mannose. The major menaquinones were MK-9, MK-10 and MK-11. The major polar lipids were diphosphatidylglycerol and phosphatidylglycerol. The predominant fatty acids were anteiso-C15 : 0 and iso-C16 : 0. In DNA-DNA hybridization tests, strain ZD5-4T shared 43.6 and 34.2 % relatedness with C. lurida KCTC 29231T and L. psychrotolerans DSM 22824T, respectively. Based on phenotypic and chemotaxonomic characteristics, strain ZD5-4T was considered to represent a novel species of the genus Conyzicola, for which the name Conyzicola nivalis sp. nov. is proposed. The type strain is ZD5-4T (=JCM 30076T=CGMCC 1.12813T). Emended descriptions of the genus Conyzicola and Conyzicola lurida are also provided.
Assessing Response of Perimenopausal Abnormal Uterine Bleeding after Treatment

Background: Abnormal Uterine Bleeding (AUB) is caused by either Organic lesions such as genital tract infections, tumors, adenomyosis, pregnancy and its complications, systemic disorders or Dysfunctional Uterine Bleeding (DUB). In women ≥ 40 years, and certainly in menopausal patients, it mandates evaluation to confirm benign nature of the problem, by ruling out endometrial carcinoma, so that medical treatment or conservative surgery can be offered and unnecessary radical surgery can be avoided. Objectives: Categorizing of Perimenopausal women with AUB for further management according to histo-pathological report and to study the efficacy of medical management (Mainly Progestins). Material and Methods: A total of 60 patients were selected who presented with symptoms of abnormal uterine bleeding at perimenopausal age group (40-54 years). Histopathological results were evaluated after obtaining endometrial tissue and patients are treated accordingly. Treatment response was assessed and tabulated. Statistical Analysis has done by danielsoper.com using chi-square test. Results: Abnormal uterine bleeding was mostly seen in multiparous women with parity >2 about 63.3%. Among menstural irregularities, 45% of cases presented with menorrhagia. Most of the patients were diagnosed as Anovulatory DUB about 60%. Out of 11 hyperplasia patients, 2 (18.1%) patients diagnosed as complex hyperplasia without atypia. No progression of AUB has seen after MPA treatment among all patients with endometrial hyperplasia. Conclusion: Cyclical oral progestogens are effective in regulating and reducing irregular bleeding due to Oligo/Anovulation. Majority of the cases of endometrial hyperplasia without atypia can be successfully treated with progestogen therapy.
Computing Service Skylines over Sets of Services

We propose a skyline computation approach that enables service users to optimally access sets of services as an integrated service package. We first present a one pass algorithm based on the observation that a multi-service skyline is completely determined by single service skylines. The skyline is returned after an enumeration on a significantly reduced candidate space. We then develop a dual progressive algorithm that is able to progressively report the skyline. We conduct an experimental study to assess the performance of the skyline computation approaches.
Keeping it Real: From Faces and Features to Social Values in Deep Learning Algorithms on Social Media Images

This paper wants to supplement computational tests of deep learning vision algorithms with a sociologically grounded performance test of three widely used vision algorithms on Facebook images (Clarifai, Google Vision and Inception-v3). The test shows poor results and the paper suggests the use of a two-level labeling model that combines features with theoretically inspired accounts of the social value of pictures for uploaders. The paper contributes a suggestion for labeling categories that connects the two levels, and in conclusion discusses both advantages and disadvantages in accelerating user profiling through a better understanding of the incentives to upload images in the data-driven algorithmic society.
The Enigmatic Life History of the Symbiotic Crab Tunicotheres moseri (Crustacea, Brachyura, Pinnotheridae): Implications for Its Mating System and Population Structure

Resource-monopolization theory predicts the adoption of a solitary habit in species using scarce, discrete, and small refuges. Life-history theory suggests that temporarily stable parental dwellings favor extended parental care in species that brood embryos. We tested these two predictions with the symbiotic crab Tunicotheres moseri. This species exhibits abbreviated development and inhabits the atrial chamber of the scarce, structurally simple, long-lived, and relatively small ascidian Phalusia nigra in the Caribbean. These host characteristics should favor a solitary habit and extended parental care (EPC) in T. moseri. As predicted, males and females of T. moseri inhabited ascidians solitarily with greater frequency than expected by chance alone. The male-female association pattern and reverse sexual dimorphism (males < females) additionally suggests a promiscuous “pure-search” mating system in T. moseri. Also in agreement with theoretical considerations, T. moseri displays EPC; in addition to embryos, females naturally retain larval stages, megalopae, and juveniles within their brooding pouches. This is the first record of EPC in a symbiotic crab and the second confirmed record of EPC in a marine brachyuran crab. This study supports predictions central to resource-monopolization and life-history theories.
Eye Controlled Mobile Robot with Shared Control for Physically Impaired People

Physically impaired and disabled people are an integral part of human society. Devices providing assistance to such individuals can help them contribute to the society in a more productive way. The situation is even worse for patients with locked-in syndrome who cannot move their body at all. These problems were the motivation to develop an eye controlled robot to facilitate such patients. Readily available commercial headset is used to record electroencephalogram (EEG) signals for classification and processing. Classification based control signals were then transmitted to robot for navigation. The robot mimics a brain controlled wheelchair with eye movements. The robot is based on shared control which is safe and robust. The analysis of robot navigation for patients showed promising results.
Stable isotope constraints on the Al 2 SiO 5 'triple-point' rocks from

The Priest pluton contact aureole in the Manzano Mountains, central New Mexico preserves evidence for upper amphibolite contact metamorphism and localized retrograde hydrothermal alteration associated with intrusion of the 1.42Ga Priest pluton. Quartz-garnet and quartz-sillimanite oxygen isotope fractionations in pelitic schist document an increase in the temperatures of metamorphism from 540 � C, at a distance of 1 km from the pluton, to 690 � C at the contact with the pluton. Comparison of calculated temperature estimates with one-dimensional thermal modelling suggests that background temperatures between 300 and 350 � C existed at the time of intrusion of the Priest pluton. Fibrolite is found within 300 m of the Priest pluton in pelitic and aluminous schist metamorphosed at temperatures >580 � C. Coexisting fibrolite and garnet in pelitic schist are in oxygen isotope equilibrium, suggesting these minerals were stable reaction products during peak metamorphism. The fibrolite-in isograd is coincident with the staurolite-out isograd in pelitic schist, and K-feldspar is not observed with the first occurrence of fibrolite. This suggests that the breakdown of staurolite and not the second sillimanite reaction controls fibrolite growth in staurolite-bearing pelitic schist. Muscovite-rich aluminous schist locally preserves the Al2SiO5 polymorph triple-point assemblage - kyanite, andalusite and fibrolite. Andalusite and fibrolite, but not kyanite, are in isotopic equilibrium in the aluminous schist. Co-nucleation of fibrolite and andalusite at 580 � C in the presence of muscovite and absence of K-feldspar suggests that univariant growth of andalusite and fibrolite occurred. Kyanite growth occurred during an earlier regional metamorphic event at a temperature nearly 80 � C lower than andalusite and fibrolite growth. Quartz- muscovite fractionations in hydrothermally altered pelitic schist and quartzite are small or negative, suggesting that late isotopic exchange between externally derived fluids and muscovite, but not quartz, occurred after peak contact metamorphism and that hydrothermal alteration in pelitic schist and quartzite occurred below the closure temperature of oxygen self diffusion in quartz (<500 � C).
Pattern Recognition Approaches inspired by Artificial Immune System

In this paper, we have presented a survey on Pattern Recognition technique using a new computational paradigm of Artificial Immune System. Inspired by the biological immune system, it aims to provide solutions for problems in a vast range of domains using novel computational tools. The main use of AIS in pattern recognition is in the field of data mining. The basic immune theories used to explain how the immune system performs pattern recognition are described and their corresponding computational models are presented. We also present a survey on the applications of AIS in various fields related to pattern recognition.
User concerns with personal routers used as public Wi-fi hotspots

Cable companies and Internet Service Providers have begun to offer public wifi hotspots run through customers' in-home wireless routers. This greatly expands the number of hotspots a company can offer, but it is often done with out the consent of the customers and sometimes without informing them that it is happening. This has led to a range of privacy and security concerns among the customers whose routers are used. In this paper, we analyze 501 online comments posted to news stories about this practice to develop a taxonomy of user concerns and identify their frequency. We found only about 19% of comments were unconcerned about the practice. Of those concerned, over 40% believed the practice was a violation of autonomy. Worries about quality of service impacts were similarly common. Issues of trust, legal liability, deceptive practices, and power were also quite common. We present these results and offer a discussion of the implications.
Enhancing automatic speaker identification using phoneme clustering and frame based parameter and frame size selection

The aim of this study is to investigate variations in speaker Identification performance for the various American English phonemes for different speech parameterisation types and frame sizes. Results on KING wideband data indicate that various phonemes have different optimal parameterisation types and frame sizes. A system able to utilise these alternatives is proposed. The system is shown to improve SI system performance when optimal parameterisation schemes are substituted for each phoneme.
Making the invisible visible: Engaging school children in monitoring air pollution in London

Exposure to air pollution is a public health concern accountable for numerous health problems and tens of thousands of premature deaths each year in the UK. Despite this evidence, public understanding and awareness of the issue is low in comparison to other public health risks. Improved methods for engaging with the public to communicate this risk are required. This study aimed to investigate the impact of collecting personalized air pollution exposure data on children and parents from a London primary school in terms of perceptions of and responses to air quality. Drawing on a participatory research approach, 400 children from a London primary school learnt about air pollution. A subset of ten children measured the air pollution they were exposed to as they travelled to and from school using portable exposure monitors and GPS watches, and shared the data they collected with the whole school. Data on the impact of the approach on the school community were collected using observations, surveys distributed to all school children and their parents, and interviews with the parents and children who collected the air pollution data. Most participants said that having access to personalized data that they themselves collected increased their air pollution awareness and their desire to reduce their air pollution exposure. The children's participation in the project inspired them to think about ways in which they could influence other people's behaviour, such as proposing anti-idling campaigns and encouraging their parents to cycle or walk to school. The use of participatory methods has the potential to facilitate the dissemination of information from a small group of individuals to a bigger audience. This study suggests that participatory methods can be implemented in practice, and they have the potential to be effective and engaging tools for raising awareness of air pollution as a health risk in communities.
Reinforcement learning for bicycle control

In 1998, Randlov and Alstrom showed that reinforcement learning can be used to control a bicycle [7]. Since then, their work has enjoyed minor popularity as a benchmark problem [4, 3, 1, 6], in part because it is harder to solve than the popular cart-pole problem. We implemented Randlov’s original work using the PyBrain [9] machine learning library. We were particularly interested in how difficult it is for a human to balance the bicycle model using keyboard inputs; how much of a feat is the reinforcement learning algorithm accomplishing? To this end, we created a small game using the Panda3D library. As Randlov and Alstrom did, we also attempted to learn a controller that could drive to a goal destination. To extend their work on shaping, we tried our own suite of complex reward functions that would work well for arbitrary goal destinations. Our code is available online at https://github.com/ chrisdembia/agent-bicycle.
Myosin VIIA is a Marker for the Cone Accessory Outer Segment in Zebrafish

The accessory outer segment, a cytoplasmic structure running alongside the photoreceptor outer segment, has been described in teleost fishes, excluding the model organism zebrafish. So far, the function of the accessory outer segment is unknown. Here, we describe the ultrastructure of the zebrafish cone accessory outer segment by electron microscopy. Starting at the connecting cilium, the accessory outer segment runs parallel alongside the cone outer segment (COS). A thin plasma bridge connects the outer segment with the accessory outer segment, whose surface is enlarged by foldings and invaginations. Beside the morphological descriptions, we demonstrate that the Usher protein myosin VIIa (Myo7a) is a specific marker for the zebrafish cone accessory outer segment. Zebrafish cone photoreceptors possess a large and well‐differentiated accessory outer segment, in which the unconventional motor protein Myo7a is highly enriched. The direct cytoplasmic contact with the COS as well as the surface enlargement of the accessory outer segment suggests an important role of this structure in transport and exchange of metabolites between the COS and the surrounding retinal pigment epithelium. In future studies of the outer retina, more attention should be paid to this often neglected structure. Anat Rec, 297:1777–1784, 2014. © 2014 Wiley Periodicals, Inc.
Formation of antibodies against salmonella lipopolysaccharides during a latent infection by Friend murine leukemia virus.

A strain of the Friend leukemia virus (FV6H), after prolonged storage at -60°C, appeared to be attenuated. The progress of Friend disease induced in mice by this virus could be divided into 3 phases: Phase I, a period of about 14 days, during which signs of the disease were limited to the appearance of splenic foci; Phase II, an ensuing phase of 7 additional days, during which moderate splenomegaly and formation of splenic foci occurred, but during which the count of leukocytes in the circulating blood and the blood picture remained within normal limits; and Phase III, the phase of onset and development of typical Friend's disease. Coincident with Phases I and II of this disease syndrome, groups of mice showed reduced ability to form circulating antibodies to salmonella lipopolysaccharides. This impaired immunologic response was noted following single injections of antigen given 7 or 2 days before or 2 days after the virus and following two injections of antigen 21 days apart when the first injection was given before the virus. The results suggest that significant impairment of immunologic response precedes “clinical” onset of leukemia.
The relationship between mutation frequency and replication strategy in positive-sense single-stranded RNA viruses

For positive-sense single-stranded RNA virus genomes, there is a trade-off between the mutually exclusive tasks of transcription, translation and encapsidation. The replication strategy that maximizes the intracellular growth rate of the virus requires iterative genome transcription from positive to negative, and back to positive sense. However, RNA viruses experience high mutation rates, and the proportion of genomes with lethal mutations increases with the number of replication cycles. Thus, intracellular mutant frequency will depend on the replication strategy. Introducing apparently realistic mutation rates into a model of viral replication demonstrates that strategies that maximize viral growth rate could result in an average of 26 mutations per genome by the time plausible numbers of positive strands have been generated, and that virus viability could be as low as 0.1 per cent. At high mutation rates or when a high proportion of mutations are deleterious, the optimal strategy shifts towards synthesizing more negative strands per positive strand, and in extremis towards a ‘stamping-machine’ replication mode where all the encapsidated genomes come from only two transcriptional steps. We conclude that if viral mutation rates are as high as current estimates suggest, either mutation frequency must be considerably higher than generally anticipated and the proportion of viable viruses produced extremely small, or replication strategies cannot be optimized to maximize viral growth rate. Mechanistic models linking mutation frequency to replication mechanisms coupled with data generated through new deep-sequencing technologies could play an important role in improving the estimates of viral mutation rate.
Is There a Future for Interleukin 17 Blocking Agents in Rheumatoid Arthritis?

Rheumatoid arthritis (RA) is a chronic inflammatory disease characterized by synovitis leading to the progressive destruction of the joints and irreversible disability. The pathophysiology of the disease is complex with various groups of immune and joint cells, soluble mediators, and autoantibodies identified to participate in the pathogenesis. Different animal models have provided a better understanding of the altered immune functions and regulation in RA. In such models, recent research has focused on Th17 cells and interleukin (IL) 17 production to demonstrate a central role in the synovitis and the destruction of joint and bone1. However, the extrapolation of the immunopathology of RA animal models to human diseases remains controversial. In recent years, our knowledge about the pathomechanisms of RA has expanded to such a degree that specific therapies targeting various cells or soluble mediators of inflammation have been developed. Tumor necrosis factor-α (TNF-α) has been largely described in the literature as a key player in RA, but the ongoing demonstration of the involvement of other mediators gives us alternative treatment options. T cells are another important target in autoimmune diseases such as RA, as confirmed by the effective use of abatacept, an agent that selectively blocks T cell costimulation2. Recently, studies in RA have demonstrated that T cells, including Th17 cells, infiltrate the joints and that IL-17 promotes osteoclastogenesis, suggesting an appropriate target3 … Address correspondence to Dr. P. Durez; E-mail: Patrick.Durez{at}uclouvain.be
An Algorithm for Computing Minimal Bidirectional Linear Recurrence Relations

We consider the problem of computing a linear recurrence relation (or equivalently a linear feedback shift register) of minimum order for a finite sequence over a field, with the additional requirement that not only the highest but also the lowest coefficient of the recurrence is nonzero. Such a recurrence relation can then be used to generate the sequence in both directions (increasing or decreasing order of indices), so we call it bidirectional. If the field is finite, a sequence is periodic if and only if it admits a bidirectional linear recurrence relation. For solving the above problem we propose an algorithm similar to the Berlekamp-Massey algorithm and prove its correctness. We describe the set of all solutions to this problem and show that if a sequence admits more than one linear recurrence relation then it admits a bidirectional one. We also prove some properties regarding the bidirectionality of the recurrences of the prefixes of the sequence.
Global Dissemination of Carbapenemase-Producing Klebsiella pneumoniae: Epidemiology, Genetic Context, Treatment Options, and Detection Methods

The emergence of carbapenem-resistant Gram-negative pathogens poses a serious threat to public health worldwide. In particular, the increasing prevalence of carbapenem-resistant Klebsiella pneumoniae is a major source of concern. K. pneumoniae carbapenemases (KPCs) and carbapenemases of the oxacillinase-48 (OXA-48) type have been reported worldwide. New Delhi metallo-β-lactamase (NDM) carbapenemases were originally identified in Sweden in 2008 and have spread worldwide rapidly. In this review, we summarize the epidemiology of K. pneumoniae producing three carbapenemases (KPCs, NDMs, and OXA-48-like). Although the prevalence of each resistant strain varies geographically, K. pneumoniae producing KPCs, NDMs, and OXA-48-like carbapenemases have become rapidly disseminated. In addition, we used recently published molecular and genetic studies to analyze the mechanisms by which these three carbapenemases, and major K. pneumoniae clones, such as ST258 and ST11, have become globally prevalent. Because carbapenemase-producing K. pneumoniae are often resistant to most β-lactam antibiotics and many other non-β-lactam molecules, the therapeutic options available to treat infection with these strains are limited to colistin, polymyxin B, fosfomycin, tigecycline, and selected aminoglycosides. Although, combination therapy has been recommended for the treatment of severe carbapenemase-producing K. pneumoniae infections, the clinical evidence for this strategy is currently limited, and more accurate randomized controlled trials will be required to establish the most effective treatment regimen. Moreover, because rapid and accurate identification of the carbapenemase type found in K. pneumoniae may be difficult to achieve through phenotypic antibiotic susceptibility tests, novel molecular detection techniques are currently being developed.