Miracle-dz/UniFAR-FTUs huggingface dataset:
A Network on Chip Architecture and Performance Evaluation

Networks-on-chip (NoCs) have emerged as an alternative to ad-hoc wiring or bus-based global interconnection in Systems-on-Chip (SoCs). The architecture of network significantly determines system performance. This paper proposes a network on chip architecture with 2-demention mesh topology, odd-even routing algorithm, wormhole switching technique and only input buffers. The size of packet is 20 bytes and that of flit is 5 bytes. The performance of proposed architecture is evaluated based on metrics of latency and throughput per channel under Constant Bit Rate (CBR) and Bursty traffic. For the proposed architecture, the evaluation results reveal that the average latency of whole network channels is 1.97 cycles under CBR traffic and 1.92 cycles under Bursty traffic. The average throughput of whole network channels is 8.8555 Gbps under CBR traffic and 8.8212 Gbps under Bursty traffic.
Year : 1997 The heat shock protein 83 ( Hsp 83 ) is required for Raf-mediated signalling in Drosophila

The heat shock protein Hsp90 has been shown to associate with various cellular signalling proteins such as steroid hormone receptors, src-like kinases and the serine/threonine kinase Raf. While the interaction between steroid hormone receptors and Hsp90 appears to be essential for ligand binding and activation of the receptors, the role of Hsp90 in Raf activation is less clear. We have identified mutations in the hsp83 gene, the Drosophila homologue of hsp90, in a search for dominant mutations that attenuate signalling from Raf in the developing eye. The mutations result in single amino acid substitutions in the Hsp83 protein and cause a dominant-negative effect on the function of the wild-type protein. We show that both wild-type and mutant forms of Hsp83 bind to the activated Drosophila Raf but the mutant Hsp83 protein causes a reduction in the kinase activity of Raf. Our results indicate that Hsp83 is essential for Raf function in vivo.
Effects of Temperature on Circadian Clock and Chronotype: An Experimental Study on a Passerine Bird

Daily schedules of many organisms, including birds, are thought to affect fitness. Timing in birds is based on circadian clocks that have a heritable period length, but fitness consequences for individuals in natural environments depend on the scheduling of entrained clocks. This chronotype, i.e., timing of an individual relative to a zeitgeber, results from interactions between the endogenous circadian clock and environmental factors, including light conditions and ambient temperature. To understand contributions of these factors to timing, we studied daily activity patterns of a captive songbird, the great tit (Parus major), under different temperature and light conditions. Birds were kept in a light (L)-dark (D) cycle (12.5 L:11.5 D) at either 8°C or 18°C with ad libitum access to food and water. We assessed chronotype and subsequently tested birds at the same temperature under constant dim light (LLdim) to determine period length of their circadian clock. Thermal conditions were then reversed so that period length was measured under both temperatures. We found that under constant dim light conditions individuals lengthened their free-running period at higher temperatures by 5.7 ± 2.1 min (p = .002). Under LD, birds kept at 18°C started activity later and terminated it much earlier in the day than those kept under 8°C. Overall, chronotype was slightly earlier under higher temperature, and duration of activity was shorter. Furthermore, individuals timed their activities consistently on different days under LD and over the two test series under LLdim (repeatability from .38 to .60). Surprisingly, period length and chronotype did not show the correlation that had been previously found in other avian species. Our study shows that body clocks of birds are precise and repeatable, but are, nonetheless, affected by ambient temperature. (Author correspondence: marina.lehmann@uni-konstanz.de)
Employees Motivation in Organizations: An integrative literature review

Aim: The purpose of this paper is to present findings of an integrative literature review related to employees' motivational practices in organizations. Method: A broad search of computerized databases focusing on articles published in English during 1999- 2010 was completed. Extensive screening sought to determine current literature themes and empirical research evidence completed in employees' focused specifically on motivation in organization. Results: 40 articles are included in this integrative literature review. The literature focuses on how job characteristics, employee characteristic, management practices and broader environmental factors influence employees' motivation. Research that links employee's motivation is both based on qualitative and quantitative studies. Conclusion: This literature reveals widespread support of motivation concepts in organizations. Theoretical and editorial literature confirms motivation concepts are central to employees. Job characteristics, management practices, employee characteristics and broader environmental factors are the key variables influence employees' motivation in organization.
Robust Network Design using Topology Characteristics

This paper studies robust network recovery method using logical ring architecture embedded in network topology. We present topology information based capacity provisioning methods for WDM optical networks which are widly used as a backbone architecture of current Internet. The efficiency of spare capacity provisioning is a key issue in survivable network design. In the methods, the spare wavelengths are reserved to perform optical link protection using only topology information of a network without need to calculate the amount of on-going traffic of the network, thus provide simple and efficient spapre capacity planning. The basic idea of the topology information based methods is embedding virtual cycles to perform recovery on the network topology graphs. We compare the proposed scheme with other topology information based schemes. We provide performance analysis of the topology information based schemes by the numerical calculation using cut-sets of the topology graphs, and compare it with computer simulation results.
Racial Residential Segregation: A Fundamental Cause of Racial Disparities in Health

Racial residential segregation is a fundamental cause of racial disparities in health. The physical separation of the races by enforced residence in certain areas is an institutional mechanism of racism that was designed to protect whites from social interaction with blacks. Despite the absence of supportive legal statutes, the degree of residential segregation remains extremely high for most African Americans in the United States. The authors review evidence that suggests that segregation is a primary cause of racial differences in socioeconomic status (SES) by determining access to education and employment opportunities. SES in turn remains a fundamental cause of racial differences in health. Segregation also creates conditions inimical to health in the social and physical environment. The authors conclude that effective efforts to eliminate racial disparities in health must seriously confront segregation and its pervasive consequences.
Parent Report of Communication Skills of Jamaican Children With Autism Spectrum Disorder: A Pilot Study

Most research related to communication skills in children with autism spectrum disorder (ASD) has been obtained from monolingual English-speaking children from high-income countries. Based on questionnaires completed by parents, this pilot study aimed to describe the communication characteristics of six children with ASD living in Jamaica. Parents had concerns about their child’s speech intelligibility, expressive language, and social communication. All children were reported to speak using Standard Jamaican English (SJE). Exposure to SJE and Jamaican Creole (JC) was reported by half of the parents. Emergent literacy was considered a relative strength. All parents reported that their child could recite the alphabet and identify some letters and that family members also helped their child print and read letters or words. Other aspects of the home literacy environment and early literacy skills were varied. Information from this group provides some insights into communication skills in children with ASD from Caribbean backgrounds.
Panoramic Measurements of the Apex of the Cochlea

Our understanding of cochlear mechanics is impeded by the lack of truly panoramic data. Sensitive mechanical measurements cover only a narrow cochlear region, mostly in the base. The global spatiotemporal pattern of vibrations along the cochlea cannot be inferred from such local measurements but is often extrapolated beyond the measurement spot under the assumption of scaling invariance. Auditory nerve responses give an alternative window on the entire cochlea, but traditional techniques do not allow recovery of the effective vibration pattern. We developed a new analysis technique to measure cochlear amplitude and phase transfer of fibers with characteristic frequencies <5 kHz. Data from six cats yielded panoramic phase profiles along the apex of the cochlea for an ∼5 octave range of stimulus frequencies. All profiles accumulated systematic phase lags from base to apex. Phase accumulation was not gradual but showed a two-segment character: a steep segment (slow propagation) around the characteristic position of the stimulus, and a shallow segment (fast propagation) basal to it. The transition between the segments occurred in a narrow region and was smooth. Wavelength near characteristic position decreased from ∼3.5 to ∼1 mm for frequencies from 200 to 4000 Hz, corresponding to phase velocities of ∼0.5 to ∼5 m/s. The accumulated phase lag between the eardrum and characteristic position varied from ∼1 cycle at 200 Hz to ∼2.5 cycle at 4 kHz, invalidating scaling invariance. The generic character of our analysis technique and its success in solving the difficult problem of reconstructing the effective sensory input from neural recordings suggest its wider application as a powerful alternative to customary system analysis techniques.
Problematising problematisation: insights from critical pedagogy in a writing lesson in Bangladesh

Abstract Problematisation is the means by which critical pedagogy attempts to destabilise power relations related to gender, race, class, identity etc. Studies in critical pedagogy in language teaching explore different ways of problematisation treating problematisation as classroom practice. However, they do not specifically address the teacher’s struggle in employing problematisation and the learners’ experience with it in classroom settings. Hence the complexity of problematisation remains neglected in research in critical pedagogy in classroom contexts. This article explores the notion of problematisation through an analysis of a writing lesson involving undergraduate students in Bangladesh. It analyses both the teacher’s and a student’s encounters with and reflections on problematisation throughout the lesson, and reveals that problematisation embodies complexities, and is empowering when it is self-reflexive.
Evidence for a role of the ileum in the control of nitrogen homeostasis via the regulation of arginine metabolism

As arginine plays a key role in the regulation of liver ureagenesis, we hypothesised that a modulation of enzymes involved in arginine metabolism within the intestine contributes to the regulation of N homeostasis according to protein supply. Our aim was to study the influence of variations in protein or amino acid (AA) supply on intestinal arginase, glutaminase, ornithine aminotransferase (OAT), argininosuccinate lyase and argininosuccinate synthetase. We evaluated in vivo in rats the responses of these enzymes to short-term (ST, 16 h) and long-term (LT, 15 d) variations in dietary protein (10, 17 or 25 % protein diet). In addition, in order to test whether these responses could involve a direct action of AA on the gene expression and activity of these enzymes, Caco-2/TC7 cells were cultured for 3 d with increasing AA concentrations. In vivo, in the ST, both high- and low-protein diets increased arginase activity in the intestinal mucosa (ST25 %: 46 (sem 2) μmol/g per min and ST10 %: 46 (sem 2) μmol/g per min v. ST17 %: 36 (sem 3) μmol/g per min, P < 0·05). In the LT, OAT expression was increased in the LT10 % group (+277 %, P < 0·05) compared with the LT17 % group. Caco-2/TC7 cells showed inverse relationships between AA supply and arginase (P = 0·058) and OAT (P = 0·035) expressions. The present study demonstrates the regulation of intestinal arginase and OAT expressions in response to protein supply. Our in vitro experiments further indicate a direct AA-induced regulation of the mRNA abundance of these enzymes. In situations of limited protein supply, this regulation would increase intestinal arginine catabolism and, possibly via a decrease in arginine portal release, decrease hepatic AA oxidation, thus promoting N sparing.
Informant Discrepancies in the Assessment of ASD Symptoms of High-Functioning Children With ASD Using the SRS–2

ABSTRACT This study compared ratings by parents and teachers of 120 high-functioning children with autism spectrum disorder on the Social Responsiveness Scale–2. Parent ratings were significantly higher than those of teachers; correlations between the informants were low to moderate. Parent–teacher pairs placed 87% of cases above the clinically significant threshold. Implications for screening, diagnosis, and outcome assessment are provided.
Prognostic models in coronary artery disease: Cox and network approaches

Predictive assessment of the risk of developing cardiovascular diseases is usually provided by computational approaches centred on Cox models. The complex interdependence structure underlying clinical data patterns can limit the performance of Cox analysis and complicate the interpretation of results, thus calling for complementary and integrative methods. Prognostic models are proposed for studying the risk associated with patients with known or suspected coronary artery disease (CAD) undergoing vasodilator stress echocardiography, an established technique for CAD detection and prognostication. In order to complement standard Cox models, network inference is considered a possible solution to quantify the complex relationships between heterogeneous data categories. In particular, a mutual information network is designed to explore the paths linking patient-associated variables to endpoint events, to reveal prognostic factors and to identify the best possible predictors of death. Data from a prospective, multicentre, observational study are available from a previous study, based on 4313 patients (2532 men; 64±11 years) with known (n=1547) or suspected (n=2766) CAD, who underwent high-dose dipyridamole (0.84 mg kg−1 over 6 min) stress echocardiography with coronary flow reserve (CFR) evaluation of left anterior descending (LAD) artery by Doppler. The overall mortality was the only endpoint analysed by Cox models. The estimated connectivity between clinical variables assigns a complementary value to the proposed network approach in relation to the established Cox model, for instance revealing connectivity paths. Depending on the use of multiple metrics, the constraints of regression analysis in measuring the association strength among clinical variables can be relaxed, and identification of communities and prognostic paths can be provided. On the basis of evidence from various model comparisons, we show in this CAD study that there may be characteristic factors involved in prognostic stratification whose complexity suggests an exploration beyond the analysis provided by the still fundamental Cox approach.
Mapping real-life applications on run-time reconfigurable NoC-based MPSoC on FPGA

Multiprocessor systems-on-chip (MPSoC) are required to fulfill the performance demand of modern real-life embedded applications. These MPSoCs are employing Network-on-Chip (NoC) for reasons of efficiency and scalability. Additionally, these systems need to support run-time reconfiguration of their components to cater to dynamically changing demands of the system. Designing and programming such systems for real-life applications prove to be a major challenge. This paper demonstrates the designing of reconfigurable NoC-based MPSoC and programming it for real-life applications. The NoC is reconfigured at run-time to support different combinations of multiple applications at different times. The platform is verified with a case study executing the parallelized C-codes of a simple producer-consumer and JPEG decoder applications on a NoC-based MPSoC on a Xilinx FPGA. Based on our investigations to map the applications on a 3×3 platform, we show that the NoC reconfiguration overhead is kept at a minimum and the platform utilizes 85% of the total available slices of Virtex-5 FPGA. Moreover, we show that the proposed approach is highly scalable when targeting for large number of applications.
The Smaller, the Shrewder: A Simple Malicious Application Can Kill an Entire SDN Environment

Security vulnerability assessment is an important process that must be conducted against any system before the deployment, and emerging technologies are no exceptions. Software-Defined Networking (SDN) has aggressively evolved in the past few years and is now almost at the early adoption stage. At this stage, the attack surface of SDN should be thoroughly investigated and assessed in order to mitigate possible security breaches against SDN. Inspired by the necessity, we reveal three attack scenarios that leverage SDN application to attack SDNs, and test the attack scenarios against three of the most popular SDN controllers available today. In addition, we discuss the possible defense mechanisms against such application-originated attacks.
Efficient hyperplane tracking by intelligent region selection

The main aim of our work is to improve the accuracy of the hyperplane tracker of F. Jurie and M. Dhome (see IEEE Trans. Pattern Anal. and Machine Intelligence, vol.24, no.7, p.996-1000, 2002) for real-time template matching. As the computation time of the initialization of the algorithm depends on the number of points used for estimating the motion of the template, only a subset of points in the tracked template is considered. Traditionally, this subset is determined at random. We present three different methods for selecting points better suited for the hyperplane tracker. We also propose to incorporate color information by working with eigenintensities instead of gray-level intensities, which can greatly improve the estimation accuracy, but only entails a slight increase in computation time. We have carefully evaluated the performance of the proposed methods in experiments with real image sequences.
Knowledge Calibration

The purpose of this article is to describe the concept of knowledge calibration within the context of knowledge management. Knowledge calibration is a concept borrowed from the psychology of decision making. It refers to the correspondence between knowledge accuracy and the confidence with which knowledge is held. Calibration is a potentially important concept for knowledge management because it describes one of the subtle errors that can lead to poor decisions. Where the correspondence between the accuracy of one’s knowledge and the confidence in that knowledge is high, decisions are described as well calibrated; but poor correspondence implies miscalibrated decisions. Since one concern of the field of knowledge management is the best use of knowledge for decision-making purposes, this topic is relevant. BACKGROUND
Extraction of Local Features for Tri-Phone Based Bangla ASR

Inherent features of the Bangla (widely used as Bengali) language like long and short vowels and many instances of allophones make it difficult to build a continuous speech recognizer for the language. Stress and accent vary in spoken Bangla language from region to region. But in formal read Bangla speech, stress and accents are ignored. There are three approaches to continuous speech recognition (CSR) based on the sub-word unit viz. word, phoneme and syllable. Pronunciation of words and sentences are strictly governed by set of linguistic rules. Many attempts have been made to build continuous speech recognizers for Bangla for small and restricted tasks. However, medium and large vocabulary CSR for Bangla is relatively new and not explored. In this paper, the authors have attempted for extracting local features (LFs) from a Bangla input speech for tri-phone based automatic speech recognition (ASR) method. The method comprises two stages, where the first stage extracts LFs from input speech and the final stage generates word strings based on trip hone hidden Markov models (HMMs). The objective of this research is to build a medium vocabulary trip hone based continuous speech recognizer for Bangla language by extracting LFs over mel frequency cepstral coefficients (MFCCs). In this experimentation using Bangla speech corpus prepared by us, the recognizer provides higher word accuracy, word correct rate as well as sentence correct rate for trained and tested sentences with fewer mixture components in HMMs.
Nerve Terminal Withdrawal from Rat Neuromuscular Junctions Induced by Neuregulin and Schwann Cells

Schwann cells (SCs) that cap neuromuscular junctions (nmjs) play roles in guiding nerve terminal growth in paralyzed and partially denervated muscles; however, the role of these cells in the day-to-day maintenance of this synapse is obscure. Neuregulins, alternatively spliced ligands for several erbB receptor tyrosine kinases, are thought to play important roles in cell–cell communication at the nmj, affecting synapse-specific gene expression in muscle fibers and the survival of terminal SCs during development. Here we show that application of a soluble neuregulin isoform, glial growth factor II (GGF2), to developing rat muscles alters terminal SCs, nerve terminals, and muscle fibers. SCs extend processes and migrate from the synapse. Nerve terminals retract from acetylcholine receptor-rich synaptic sites, and their axons grow, in association with SCs, to the ends of the muscle. These axons make effective synapses only after withdrawal of GGF2. These synaptic alterations appear to be induced by the actions of neuregulin on SCs, because SC transplants growing into contact with synaptic sites also caused withdrawal of nerve terminal branches. These results show that SCs can alter synaptic structure at the nmj and implicate these cells in the maintenance of this synapse.