Miracle-dz/UniFAR-FTUs huggingface dataset:
Analysis of The Addition Polypropylene Fibre and 8670 Mn Viscocrete added Material on The Split Tensile Strength and Modulus of Elasticity of Concrete

This study used waste coconut fibre and HDPE plastic as partial aggregate replacement materials. Coconut fibre ash has pozzolanic properties, which contain high silicate elements. High-density polyethene (HDPE) plastic has more potent, complex, opaque material properties and is more resistant to high temperatures. Superplasticizer is an admixture added to concrete during mixing and during placing to improve its strength performance. This study aims to study the effect of adding HDPE plastic as a substitute for coarse aggregate, coconut fibre ash as a substitute for fine aggregate and Viscrocrete-8670 MN on absorption, concrete compressive strength and elastic modulus of concrete. With variations in the addition of BN HDPE plastic, 0.5%, 1%, and 1.5%, the coarse aggregate passed 3/8 filter retained by filter no 4, 3% coconut fibre ash for each variation of concrete and Viscrocrete-8670 MN by 0.8% by weight of cement. The maximum value for each concrete test is the absorption value of concrete (4.23% for regular concrete), compressive strength (32.49 MPa for 1.5% HDPE concrete), and the modulus of elasticity (3152 MPa for 1.5% HDPE concrete).
Study on Multichannel Discharge Characteristics of Multigap Gas Switch Gaps

Multigap gas spark switches are commonly utilized in linear transformer drivers (LTDs) because of their outstanding static and triggering performance. The number of discharge channels in the switch gap has an effect on the inductance and dissipated energy of the switches. To explore the multichannel discharge characteristics of the switch gaps, a two-gap gas switch (TGGS) with one trigger gap and one self-breakdown gap is designed. The trigger experiments are conducted on the TGGS under various switch working coefficients and nanosecond trigger pulses with different rise rates. The number of discharge channels in the switch gap is recorded by a intensified charge-coupled device (ICCD) camera. The frequency distribution of the number of discharge channels in the trigger gap and the self-breakdown gap is shown under different operating conditions. The experimental results indicate that the number of discharge channels in the self-breakdown gap is significantly more than that in the trigger gap. The preionization obviously increases the number of discharge channels in the trigger gap. The influence of the number of discharge channels in the switch ON the discharge loop current is discussed, and the inductance and dissipated energy of spark channels in the switch gap under different trigger settings are calculated. Increasing the trigger voltage rise rate, the working coefficient, or introducing preionization can correspondingly promote the number of discharge channels in the switch gap, which reduces the inductance and dissipated energy of the switch and thus improves the rise rate and amplitude of the brick current.
Exploring the Prognostic Significance and Immunotherapeutic Potential of Single-Cell Sequencing-Identified Long Noncoding RNA (LncRNA) in Patients With Non-small Cell Lung Cancer

Background: Single-cell RNA sequencing technology can provide insight into lung cancer. The purpose of this study was to analyze the relationship between long noncoding RNA (lncRNA) discovered by RNA sequencing and immunotherapy in patients with non-small cell lung cancer (NSCLC). Methods: In this study, we utilized data from The Cancer Genome Atlas (TCGA) to extract gene expression data and prognostic information from patients with NSCLC. We employed univariate, least absolute shrinkage and selection operator (LASSO), multivariate Cox regression analyses to construct risk models, and Kaplan-Meier (KM) analysis to compare survival differences between high- and low-risk groups. To evaluate the accuracy of our risk model predictions, we utilized a nomogram, calibration curve, correlation index curve (C-index), and receiver operating characteristic (ROC). Additionally, we conducted Gene Ontology (GO) enrichment analysis and Kyoto Encyclopedia of Genes and Genomes (KEGG) enrichment analysis to investigate the differential expression of lncRNA genes. We also used the tumor immune dysfunction and exclusivity (TIDE) algorithm and the R package "pRRophetic" to analyze the tumor microenvironment. Finally, we utilized stem cell indices based on mRNA expression-based stemness index (mRNAsi) expression to better assess patient prognosis. Results: Our analysis identified a set of 28 lncRNAs with prognostic risk profiles in patients with lung adenocarcinoma. Notably, patients in the low-risk group exhibited significantly better overall survival (OS) compared to those in the high-risk group. Kaplan-Meier (KM) survival curves revealed that these prognostic risk markers accurately predicted survival outcomes in non-small cell lung cancer (NSCLC) patients. MerCK18 and myeloid-derived suppressor cells (MDSC) were strongly associated with immune escape and immunotherapy in high- and low-risk subgroups. In our investigation of potential chemotherapeutic agents for the treatment of NSCLC, we screened a total of 60 agents and found that PPM1D was more effective in the low-risk group. However, we did not observe a strong correlation between the stem cell index mRNAsi and OS. Conclusion: Our study highlights the close association between lncRNAs and prognostic risk profiles and the prognosis of patients with non-small cell lung cancer, offering a promising avenue for the clinical implementation of immunotherapy.
A Calibration Method for Fish-Eye Camera of Lunar Rover

A two-step method is proposed in the paper for calibrating fish-eye camera of Lunar Rover accurately.First,the spherical projection equation is used as the fish-eye camera projection model,and the relation between spherical projection and perspective projection is modeled.Then using the property that the spherical projection of a line is ellipse arc,the coordinates of principal point of photograph and spherical radius are calculated.Second,by calculated parameters,spherical projection is transformed to perspective projection.And intrinsic parameters of fish-eye camera are calibrated.New calculated parameters are used to supersede old ones to calibrate iteratively the intrinsic parameters.The process stops until the calibrated result is converged to a design value.An experiment is carried out to validate the method in the paper.
Brain Computer Interface (BCI) Machine Learning Process: A Review

The abstraction of Brain Computer Interface (BCI) is a communication and control system that translated human mind thoughts into real-world interaction without any use of neural pathways and muscles. BCI is used as a tool to help person that suffered from impairment to be able do their daily activities independently. In general, BCI process its signal through several process such as pre-processing, and classification. However, providing information of pre-processing and classification process is barely found. Therefore, in this review paper we present the various pre-processing and classification methods that used in the BCI system application.
High-Precision Pulse Reflectometry-Based Fault Localization Approach for Advanced Chip Package Failures

For decades, device scaling has been the primary driver of the performance boost in integrated circuit (IC) devices. However, this trend has slowed down in recent years due to physical limitations and technical challenges. To continue meeting the ever-increasing demand for high-performance computing, other innovations such as advanced transistor designs and packaging schemes have emerged. Advanced transistors, such as FinFETs and Gate-all-around FET (GAAFETs), have been developed to overcome the limitations of traditional planar transistors, offering higher performance and energy efficiency. Meanwhile, advanced packaging schemes, such as system-in-package (SiP), 2.5D, and 3D packaging, offer higher integration densities, improved thermal management, and faster data transmission. These innovations are crucial in driving the development of high-performance computing, and they will play an essential role in meeting the growing demand for faster and more efficient computing.
X-ray Investigation of CsPbI3:EuCl3 Infiltrated into Gig-Lox TiO2 Spongy Layers for Perovskite Solar Cells Applications

In this study, we explore the potential of a blended material comprising CsPbI3:EuCl3 perovskite and Gig-Lox TiO2, a unique transparent spongy material known for its multi-branched porous structure, for application in solar cells. The inclusion of EuCl3 in CsPbI3 serves to stabilize the photoactive γ-phase with a bandgap of 1.75 eV, making it suitable for solar energy conversion in tandem solar cells. Our study applies X-ray-based techniques to investigate the structural properties and interfacial behavior within this blended material, in comparison with a reference perovskite layer deposited on glass. In addition, Spectroscopic ellipsometry is complemented with density functional theory calculations and photoluminescence measurements to elucidate the absorption and radiative emission properties of the blend. Notably, our findings reveal a significant quenching of photoluminescence within the blended material, underscoring the pivotal role of the distributed interfaces in facilitating efficient carrier injection from the CsPbI3:EuCl3 perovskite into the Gig-Lox TiO2 sponge. These findings pave the way for the application of the blend as an Electron Transport Layer (ETL) in semi-transparent perovskite solar cells for tandem and building integrated photovoltaics.
Importancia Ecológica y Cultural de una Especie Endémica de Ajolote (Ambystoma Dumerilii) del Lago de Pátzcuaro, Michoacán

El achojki es una salamandra de la familia Ambystomatidae que habita en el Lago de Patzcuaro, Michoacan. Es una especie que presenta paedogenesis y es endemica del lago. Se considera amenazada y se encuentra en las listas nacionales e internacionales de conservacion. Es una especie carnivora generalista y probablemente tiene competencia interespecifica con peces dulceacuicolas, como la chehua (Alloophorus robustus), el pescado blanco (Menidia estor) y la lobina negra (Micropterus salmoides). Para los p’urhepecha tiene dos atributos utilitarios, en el ambito alimentario, por su alto contenido proteinico, se utiliza en caldo o dorado y en el medicinal, se utiliza para el tratamiento de enfermedades respiratorias y como proveedor de energia para ninos y mujeres en periodos de lactancia. Este trabajo se dividio en dos rubros, el ecologico y el cultural, para lo cual se realizo una busqueda bibliografica y visitas al campo, en las cuales se hicieron 133 entrevistas y encuestas a adultosy ninos de la region, asi como visitas a los sitios de cultivo. La mayoria de los pobladores entrevistados conoce al achoque, lo ha utilizado y piensa que ha disminuido. Las causas que han contribuido a la disminucion de la especie han sido: la eutrofizacion del lago, la disminucion del nivel de agua, la introduccion de especies exoticas y la sobreexplotacion de recursos. Existen tres sitos de cultivo dedicados al cuidado y reproduccion de la especie: la UMA Jimbani Erandi, la UMA Dumerilii, y el PIMVS Jimbani Tzipekua. Se propone que se realice un plan de manejo para la supervivencia de la especie, mediante el aprovechamiento sustentable, apoyado en las iniciativas locales.
Study on Application of Arps Decline Curves for Gas Production Forecasting in Senegal

The purpose of this study is to evaluate the feasibility of using methods for predicting the flow rates of gas wells in fields in Senegal. Accurate forecasting of natural gas production allows you to correctly set the operating mode of wells and design onshore infrastructure. One of the gas fields of Senegal was chosen as the object of study, where deposits were discovered within the exploitation perimeters in the Campanian and Santonian sandstone horizons. Gas formations have high porosity and permeability values, as well as high formation temperatures. Gas well flow rates can be predicted using hydrodynamic models, mathematical models (hyperbolic, etc.) and other methods. This study assessed the possibility of using Arps curves for long-term forecasting of gas flow rate and comparing the forecasting results with actual data. Comparison of Arps curves and actual gas flow rates for wells made it possible to note a discrepancy in the forecast results and actual values of more than 20%. These differences arose for two reasons. Deviations at the initial stage of well operation (6 months), which is associated with the adjustment of the technological operating mode of the well and the establishment of constant parameters of rocks near the wellbore. The second reason is well repairs, which change the properties of rocks near the wellbore. In general, Arps curves of exponential type showed high convergence between predicted and
Anti-Trypanosoma cruzi Activity, Mutagenicity, Hepatocytotoxicity and Nitroreductase Enzyme Evaluation of 3-Nitrotriazole, 2-Nitroimidazole and Triazole Derivatives

Chagas disease (CD), which is caused by Trypanosoma cruzi and was discovered more than 100 years ago, remains the leading cause of death from parasitic diseases in the Americas. As a curative treatment is only available for the acute phase of CD, the search for new therapeutic options is urgent. In this study, nitroazole and azole compounds were synthesized and underwent molecular modeling, anti-T. cruzi evaluations and nitroreductase enzymatic assays. The compounds were designed as possible inhibitors of ergosterol biosynthesis and/or as substrates of nitroreductase enzymes. The in vitro evaluation against T. cruzi clearly showed that nitrotriazole compounds are significantly more potent than nitroimidazoles and triazoles. When their carbonyls were reduced to hydroxyl groups, the compounds showed a significant increase in activity. In addition, these substances showed potential for action via nitroreductase activation, as the substances were metabolized at higher rates than benznidazole (BZN), a reference drug against CD. Among the compounds, 1-(2,4-difluorophenyl)-2-(3-nitro-1H-1,2,4-triazol-1-yl)ethanol (8) is the most potent and selective of the series, with an IC50 of 0.39 µM and selectivity index of 3077; compared to BZN, 8 is 4-fold more potent and 2-fold more selective. Moreover, this compound was not mutagenic at any of the concentrations evaluated, exhibited a favorable in silico ADMET profile and showed a low potential for hepatotoxicity, as evidenced by the high values of CC50 in HepG2 cells. Furthermore, compared to BZN, derivative 8 showed a higher rate of conversion by nitroreductase and was metabolized three times more quickly when both compounds were tested at a concentration of 50 µM. The results obtained by the enzymatic evaluation and molecular docking studies suggest that, as planned, nitroazole derivatives may utilize the nitroreductase metabolism pathway as their main mechanism of action against Trypanosoma cruzi. In summary, we have successfully identified and characterized new nitrotriazole analogs, demonstrating their potential as promising candidates for the development of Chagas disease drug candidates that function via nitroreductase activation, are considerably selective and show no mutagenic potential.
The impact of the comorbid seizure/epilepsy on the health related quality of life in people with multiple sclerosis: an international multicentric study

Introduction The health-related quality of life (HRQoL) of people with (Pw) multiple sclerosis (MS) is usually deteriorated. It has been recently suggested that comorbidities may have the negative influence on the quality of life of the PwMS, but according to the best of our knowledge, only one study investigated, although in a very small cohort, the impact of individual comorbidity on the quality of life of PwMS. The aim of our investigation was to assess, in an international, multicentric study, the impact of comorbid seizure/epilepsy on the HRQoL in PwMS. Methods We conducted cross-sectional study at numerous neurological centers in Serbia, Croatia, Bulgaria, Montenegro, Northern Macedonia, and Bosnia and Herzegovina (Federation of Bosnia and Herzegovina and Republic of Srpska). For each patient, demographic and clinical data were collected, including Expanded disability status scale (EDSS) score. Beck Depression Inventory (BDI) and the 36-Item Short Form Health Survey (SF-36) questionnaires were administered to all patients. Results The study comprised 326 PwMS in total, 127 PwMS with seizure/epilepsy and 209 PwMS without. Both mean Physical health composite (PHC) and mental health composite (MHC) scores, were statistically significantly higher in PwMS without seizure/epilepsy, implicating worse quality of life in PwMS with comorbid seizure/epilepsy. Presence of seizure/epilepsy in pwMS was statistically significant independent predictor of both PHC and MHC, in multivariate linear regression model after adjustment for potential confounding variables. The hierarchical multivariate regression analysis was performed in order to establish the most important predictors of the PHC and MHC of the SF-36, in PwMS with seizure/epilepsy; older age, higher level of disability, as measured by EDSS, higher depression score, drug-resistant epilepsy and shorter time since last seizure were found to significantly predict worse MHC score in PwMS with seizure/epilepsy. Discussion Our results point to the possible role of theinterventions related to the adequate control of epilepsy along with improvement of the mental health status to be important in order to reduce MS burden in the PwMS with comorbid seizure/epilepsy.
Correlation between severe malaria and EBV endemicity in children under five years in Ghana

In Africa, Plasmodium falciparum accounts for majority of malaria morbidity and mortality in children under five years. At this age, they also become co-infected with Epstein-Barr virus (EBV). There is scanty of information whether this co-infection is the reason why malaria in children tends to be severe. The aim was to study the association between co-infection of EBV with P. falciparum infection and malaria severity in children under five. A cross sectional study was conducted among eighty children below five years who had been confirmed to have malaria. These children were grouped into those who had severe malaria and those who did not have severe malaria. EBV antibodies (EBNA-1 IgG) and malaria parasitaemia were measured from the blood samples of the children using ELISA and microscopy, respectively. EBV seroprevalence was higher in the severe malaria group, 16 (32.78%) compared to non-severe malaria group, 5 (16.1%); although it did not show any significant difference (Risk ratio: 2.024, 95% CI: 0.8249 to 4.9686, p = 0.1236). Despite the higher seroprevalence of EBV in the severe malaria group, this was not responsible for malaria severity. Children with EBV were however more likely to progress to severe malaria.
Effect of salinity variation on intestinal microbiota of the Indian white shrimp Penaeus indicus H. Milne Edwards, 1837

The effects of salinity adaptation on gut microbiota of juvenile Indian white shrimp, Penaeus indicus H. Milne Edwards, 1837 was analysed in this experiment. Intestines of shrimps adapted to two different salinities were examined using 16S rRNA amplicon sequencing. At all salinity levels, the dominant phyla recorded were Proteobacteria followed by Bacteroidota and Fusobacteriota. However, as the salinity decreased, abundance of Proteobacteria increased while richness of Bacteroidota and Fusobacteriota decreased significantly. At genus level, salinity reduction increased the abundance of Vibrio and Photobacterium; while it decreased the abundance of Spongiimonas and Hypnocyclicus. The survival of animals in both the groups was not affected but the weight gain was less in low saline group (5 ppt). The results confirm the influence of salinity in rearing water on the intestinal microbiota of shrimp. Keywords: Aquaculture, Bacteroidota, Fusobacteriota, Hypnocyclicus, Proteobacteria, Salinity, Spongiimonas
Can Small-Scale Agricultural Production Improve Children's Health? Examining Stunting Vulnerability among Very Young Children in Mali, West Africa

Stunting affects an individual's educational and wage-earning potential and can even affect the next generation of children. Most research of childhood stunting focuses on the determinants and correlates that lead to stunting—through nutritional or early infant experiences, with one potential solution to stunting being an increased supply of locally produced food. This research examines the interplay of community-level cropped area as a factor relating to childhood stunting. We use the most recently collected Demographic and Health Survey (DHS) data for Mali, very high resolution remotely sensed imagery, and other remotely sensed data relating to geophysical characteristics to examine the impact of local cultivation on children's health. We focus on evaluating the environmental, community, household, and individual characteristics of the children who report healthy anthropometrics despite the presence of specific stunting risk factors. In adopting this approach to studies of children's health we can shed light on how small-scale agricultural production impacts childhood stunting among at-risk children.
QTAIM analysis for Metal - Metal and Metal- Non-metal Bonds in Tri-Osmium cluster

Electron density of the interaction of the compound's chemical bonding has been computed using topological analysis. The findings suggest that Os-Os, Os-N, and Os-H bonds have experienced bond critical points (BCP) with corresponding bonds paths (BP). The presence of N-C bridging atoms is significantly impacted by electron density of Os2-Os3 bond distribution therefore no critical point found and bond path. So, due to their positive electron density (b), negative laplacian 2(b), and positive the total energy density H(b) values, the Os-NC, Os-H, and Os-CO bonds all have transit closed-shell topological properties.
Blockchain and City Information Modeling (CIM): A New Approach of Transparency and Efficiency

For over a decade, digital modelling has transcended geometric representations to more advanced object-based modelling using real-life attirbutes. Digital technologies, especially Building Information Modelling (BIM) have been widely adopted in the Architecture, Engineering, Construction, and Operations (AECO) industry, while a newer niche - City Information Modelling (CIM) has emerged as an extension of BIM for urban informatics. This research proposes a framework that integrates heterogeneous CIM using a multi-level, nested data environment. The CIM is developed through a network of BIM models synchronized into a Geographic Information Systems (GIS) interface. The individual BIM models are blockchain-enabled by connecting them to a distributed ledger and shared across a network of project collaborators using a Common Data Environment (CDE) in a Building Level Framework. The resulting CIM from the network of BIM models is shared between the asset owners in a City Level Framework. Use case scenarios are presented to illustrate the application of the research in real life, and research limitations are discussed. The study aims to improve management of buildings and urban assets, providing a more efficient and secure platform for collaboration and data sharing through a blockchain-CIM integration, providing opportunities for further research in digital modelling and smart technologies.