Miracle-dz/UniFAR-FTUs huggingface dataset:
A permeabilized cell model for studying cell division: a comparison of anaphase chromosome movement and cleavage furrow constriction in lysed PtK1 cells

After lysis in a Brij 58-polyethylene glycol medium, PtK1 cells are permeable to small molecules, such as erythrosin B, and to proteins, such as rhodamine-labeled FAB, myosin subfragment-1, and tubulin. Holes are present in the plasma membrane, and the mitochondria are swollen and distorted, but other membrane-bounded organelles of the lysed cell model are not noticeably altered. After lysis, the mitotic apparatus is functional; chromosomes move poleward and the spindle elongates. Cells lysed while in cytokinesis will continue to divide for several minutes. Addition of crude tubulin extracts, MAP-free tubulin, or taxol to the lysis medium retards anaphase chromosome movements but does not affect cleavage. On the other hand, N-ethylmaleimide-modified myosin subfragment-1, phalloidin, and cytochalasin B inhibit cleavage but have no effect on anaphase chromosome movements under identical lysis conditions. These results suggest that actomyosin plays no functional role in anaphase chromosome movement in mammalian tissue culture cells and that microtubule depolymerization is a rate-limiting step for chromosome-to-pole movements.
Struggles for Educational Equity in Prince Edward County, VA: Resistance, Southern Manifesto Ideologies, and School Choice

ABSTRACT In light of contemporary school choice proposals and the 60th anniversary of the Southern Manifesto, the Prince Edward County, Virginia public schools crisis provides interesting historical discussion. Prince Edward County (PEC), a rural community in central Virginia, was one of five school districts represented in the 1954 Brown v. Board of Education Supreme Court decision that ruled segregated public schools unconstitutional. In response to this decision, PEC closed public schools from 1959–1964 rather than desegregate them. Three other Virginia locales closed public schools to resist the desegregation mandate of Brown—Warren County, Charlottesville, and Norfolk—but none for as long as PEC. Like the 19 Senators and 82 Representatives from each of the former Confederate states who signed the Declaration of Constitutional Principles or “Southern Manifesto” and understood the Brown ruling as a violation of state’s rights, Virginia lawmakers also vowed “…to use all lawful means to bring about a reversal of this decision [Brown] which is contrary to the Constitution and to prevent the use of force in its implementation. ”
An Efficient Pipelined Technique for Signcryption Algorithms

Signcryption algorithms are based on public key cryptography. The main advantage of signcryption algorithms is to provide both confidentiality and authenticity in one step. Hence, signcryption algorithms lower both communication and computation overheads. This reduction, in communication and computation overheads, makes signcryption algorithms more suitable for realtime applications than other algorithms that combine encryption and digital signature in separate blocks. Although, the signcryption algorithms overcome the communication overhead problem, they still suffer from the need to perform arithmetic modular operations. The arithmetic modular operations have high computation overhead. In this paper, we use a pipelined technique to reduce the computation overhead of signcryption algorithms. We apply the proposed pipelined technique to Rasslan et. al signcryption algorithm. The proposed pipelined technique is suitable for the selected signcryption algorithm. Rasslan et. al. signcryption algorithm is more efficient than all the previously presented algorithms. Rasslan et. al. signcryption algorithm allows the recipient to recover the message blocks upon receiving their corresponding signature blocks. This makes Rasslan et. al signcryption algorithm perfect for some real-time applications. Also, we illustrate the performance analysis of the proposed solution. The performance analysis shows that the proposed technique reduces the computation time required to execute Rasslan et. al. signcryption algorithm with respect to its corresponding values of sequential execution.
Diagnostic Performance on Low Dose Computed Tomography For Acute Appendicitis Among Attending and Resident Radiologists

Background Low-dose computed tomography (LDCT) techniques can reduce exposure to radiation. Several previous studies have shown that radiation dose reduction in LDCT does not decrease the diagnostic performance for appendicitis among attending radiologists. But, the LDCT diagnostic performance for acute appendicitis in radiology residents with variable training levels has not been well discussed. Objectives To compare inter-observer and intra-observer differences of diagnostic performance on non-enhanced LDCT (NE-LDCT) and contrast-enhanced standard dose CT (CE-SDCT) for acute appendicitis among attending and resident radiologists. Patients and Methods This retrospective study included 101 patients with suspected acute appendicitis who underwent NE-LDCT and CE-SDCT. The CT examinations were interpreted and recorded on a five-point scale independently by three attending radiologists and three residents with 4, 1 and 1 years of training. Diagnostic performance for acute appendicitis of all readers on both examinations was represented by area under receiver operating characteristic (ROC) curves. Inter-observer and intra-observer AUC values were compared using Jackknife FROC software on both modalities. The diagnostic accuracy of each reader on NE-LDCT was compared with body mass index (BMI) subgroups and noise using independent T test. Results Diagnostic performances for acute appendicitis were not statistically different for attending radiologists at both examinations. Better performance was noted on the CE-SDCT with a borderline significant difference (P = 0.05) for senior radiology resident. No statistical difference of AUC values was observed between attending radiologists and fourth year resident on both examinations. Statistically signiﬁcant differences of AUC values were observed between attending radiologists and first year residents (P = 0.001 ~ 0.018) on NE-LDCT. Diagnostic accuracies of acute appendicitis on NE-LDCT for each reader were not significantly related to BMI or noise. Conclusion Attending radiologists could diagnose acute appendicitis accurately on NE-LDCT. Performance of senior residents on NE-LDCT is better than junior residents and comparable to attending radiologists.
Extinction Times for Birth-Death Processes: Exact Results, Continuum Asymptotics, and the Failure of the Fokker-Planck Approximation

We consider extinction times for a class of birth-death processes commonly found in applications, where there is a control parameter which defines a threshold. Below the threshold, the population quickly becomes extinct; above, it persists for a long time. We give an exact expression for the mean time to extinction in the discrete case and its asymptotic expansion for large values of the population scale. We have results below the threshold, at the threshold, and above the threshold, and we observe that the Fokker--Planck approximation is valid only quite near the threshold. We compare our asymptotic results to exact numerical evaluations for the susceptible-infected-susceptible epidemic model, which is in the class that we treat. This is an interesting example of the delicate relationship between discrete and continuum treatments of the same problem.
Overview of Visualization Tools for Web Browser History Data

Nowadays, the Web has becomeone of the most widespread platforms for information change and retrieval. As it becomes easier to publish documents, as the number of users, and thus publishers, increases and as the number of documents grows, searching for information is turning into a cumbersome and timeconsuming operation. Because of the loose interconnection between documents, people have difficulty remembering where they have been and returning to previously visited pages. Navigation through the web faces problems of locating onesel f with respect to space and time. The idea of graphical assistance navigation is to help users to find their paths in hyperspace by adapting the style of link presentation to the goals, knowledge and other characteristics of an individual user. We first introduce the concepts related to web navigation; we then present an overview of different graphical navigation tools and techniques. We conclude by presenting a comparative table of these tools based on some pertinent criteria.
PREVALENCE OF GENITAL CHLAMYDIA TRACHOMATIS INFECTION AMONG GYNAECOLOGIC CLINIC ATTENDEES IN JOS, NIGERIA

Background: Chlamydia trachomatis is the most common cause of sexually transmitted venereal infection in the world. There is little information about the prevalence of C trachomatis in Jos, Nigeria. Objectives: The study was carried out to determine the prevalence of C trachomatis infection in women attending the gynaecology clinic of the Plateau State Specialist Hospital and to assess the variables associated with the infection. Methods: A questionnaire was administered, followed by collection of endocervical swabs from patients who gave their consents using sterile plastic-shaft Dacron swabs. Collected samples were analyzed using Chlamydia Rapid Test Device- Swab/Urine (INTERCHEMICAL LTD. CHINA). Results: Samples were collected from a total of 164 women, aged between 14 and 45 years. Ninety two (56.1% of total sample) tested positive for C trachomatis. The prevalence was slightly higher in patients within the age group 25-29 (17.68%) than in the age group 20-24 (15.24%). Both age groups 15-19 and 30-34 had a prevalence of 7.93% each. The age groups 35-39, 40-44, 45-49 and <15 had prevalence of 3.66%, 3.05%, 0.16%, and 0.00% respectively. Married women were related to a higher percentage of infection than single women: 38.41% versus 17.07%. Age of onset of sexual activity played a role in infection with C trachomatis. Women who started having sex earlier in life had a higher prevalence. History of other sexually transmitted diseases was found to be significantly associated with genital C trachomatis infection (41.46%) (P<0.05). Fourteen percent of the women had history of infertility, 26.22% spontaneous abortion, 22.12% pelvic inflammatory disease (PID) and 42.68% had more than one sexual partner (past/present). Conclusion: A 56.1% prevalence of C trachomatis genital infection was found. Awareness campaigns and Chlamydia screening and monitoring activities should be initiated and supported by the government.
Iodo-resiniferatoxin, a new potent vanilloid receptor antagonist.

The highly potent vanilloid receptor (VR) agonist resiniferatoxin has been radiolabeled with 125I, and the pharmacology to the cloned rodent VR, VR1, and the endogenous VR in rat spinal cord membranes has been characterized. [125I]RTX binding to human embryonic kidney 293 cells expressing VR1 was reversible and with high affinity (Kd = 4.3 nM) in an apparent monophasic manner. In rat spinal cord membranes, [125I]RTX bound with a similar high affinity (Kd = 4.2 nM) to a limited number of binding sites (Bmax = 51 +/- 8 fmol/mg of protein). The pharmacology of recombinant rodent VR1 and the endogenous rat VR1 was indistinguishable when measuring displacement of [125I]RTX binding (i.e., the following rank order of affinity was observed: RTX > I-RTX > olvanil > capsaicin > capsazepine). Capsaicin and RTX induced large nondesensitizing currents in Xenopus laevis oocytes expressing VR1 (EC50 values were 1300 nM and 0.2 nM, respectively), whereas I-RTX induced no current per se at concentrations up to 10 microM. However, I-RTX completely blocked capsaicin-induced currents (IC50 = 3.9 nM). In vivo, I-RTX effectively blocked the pain responses elicited by capsaicin (ED50 = 16 ng/mouse, intrathecally). The present study showed that I-RTX is at least 40-fold more potent than the previously known VR antagonist, capsazepine. Thus, I-RTX as well as its radiolabeled form, should be highly useful for further exploring the physiological roles of VRs in the brain and periphery.
Intellectual Capital and Valuation: Challenges in the Voluntary Disclosure of Value Drivers

Many commentators have identified the pivotal role of intellectual capital in the valuation of firms and the determination of their future earnings. Innovation in voluntary disclosure of intellectual capital lead by European firms, such as Celemi and Skandia, has generated a plethora of new reporting frameworks such as the Balanced Scorecard. However, there has been little support by the accounting profession to recognise the value of intellectual capital or adopt a common disclosure framework. There has also been very little progress by firms in extending their voluntary reporting frameworks, beyond just rhetoric, and attempting to quantify their intellectual capital. This paper will critically evaluate the challenges faced by firms in disclosing the elements and value of their intellectual capital to the market.
“Sharenting,” parent blogging, and the boundaries of the digital self

ABSTRACT This article asks whether “sharenting” (sharing representations of one’s parenting or children online) is a form of digital self-representation. Drawing on interviews with 17 parent bloggers, we explore how parents define the borders of their digital selves and justify what is their “story to tell. ” We find that bloggers grapple with profound ethical dilemmas, as representing their identities as parents inevitably makes public aspects of their children’s lives, introducing risks that they are, paradoxically, responsible for safeguarding against. Parents thus evaluate what to share by juggling multiple obligations—to themselves, their children in the present and imagined into the future, and to their physical and virtual communities. The digital practices of representing the relational self are impeded more than eased by the individualistic notion of identity instantiated by digital platforms, thereby intensifying the ambivalence of both parents and the wider society in judging emerging genres of blogging the self.
Preference-based Player Modelling for Civilization IV

The Artificial Intelligence in modern computer games is inferior to the average human intelligence. In order to improve computer game AI, better imitation of human behaviour is required. One way to achieve better game AI is to have the computer build a player model for its opponents, so that it can base its decisions on good predictions of what the human player wants to achieve. This paper describes a way of building such a player model for the turn-based strategy game Civilization IV.
HOW SENSORY INTEGRATION WORKS IN THE ELDERLY

We all are sensory beings. As age increases, the sensory processing gets affected due to various factors. These are a direct result of aging, effect of environment on central nervous system processing, and brain plasticity. There is an abnormal sensory registration and processing due to impaired sensory systems which in turn leads to abnormal sensory integration and interpretation. As a result, poor and inappropriate adaptive responses are produced in the domains of tactile, vestibular, auditory processing, motor and social performance, and emotional regulation.
Analysis of Two Simple Heuristics on a Random Instance of k-SAT

We consider the performance of two algorithms, GUC and SC studied by M. T. Chao and J. Franco SIAM J. Comput.15(1986), 1106? 1118;Inform. Sci.51(1990), 289? 314 and V. Chvatal and B. Reed in“Proceedings of the 33rd IEEE Symposium on Foundations of Computer Science, 1992,” pp. 620? 627, when applied to a random instance ? of a boolean formula in conjunctive normal form withnvariables and ? cn? clauses of sizekeach. For the case wherek=3, we obtain the exact limiting probability that GUC succeeds. We also consider the situation when GUC is allowed to have limited backtracking, and we improve an existing threshold forcbelow which almost all ? is satisfiable. Fork? 4, we obtain a similar result regarding SC with limited backtracking.
Home based exercise programme for knee pain and knee osteoarthritis: randomised controlled trial

Abstract Objectives: To determine whether a home based exercise programme can improve outcomes in patients with knee pain. Design: Pragmatic, factorial randomised controlled trial of two years' duration. Setting: Two general practices in Nottingham. Participants: 786 men and women aged—45 years with self reported knee pain. Interventions: Participants were randomised to four groups to receive exercise therapy, monthly telephone contact, exercise therapy plus telephone contact, or no intervention. Patients in the no intervention and combined exercise and telephone groups were randomised to receive or not receive a placebo health food tablet. Main outcome measures: Primary outcome was self reported score for knee pain on the Western Ontario and McMaster universities (WOMAC) osteoarthritis index at two years. Secondary outcomes included knee specific physical function and stiffness (scored on WOMAC index), general physical function (scored on SF-36 questionnaire), psychological outlook (scored on hospital anxiety and depression scale), and isometric muscle strength. Results: 600 (76.3%) participants completed the study. At 24 months, highly significant reductions in knee pain were apparent for the pooled exercise groups compared with the non-exercise groups (mean difference -0.82, 95% confidence interval -1.3 to -0.3). Similar improvements were observed at 6, 12, and 18 months. Regular telephone contact alone did not reduce pain. The reduction in pain was greater the closer patients adhered to the exercise plan. Conclusions: A simple home based exercise programme can significantly reduce knee pain. The lack of improvement in patients who received only telephone contact suggests that improvements are not just due to psychosocial effects because of contact with the therapist.
015 Remote memory deficits in transient epileptic amnesia

Aims Transient epileptic amnesia (TEA) is a recently recognised form of temporal lobe epilepsy in which sufferers often complain of irretrievable loss of remote memories. We aimed to answer the following questions: 1) What is the extent and nature of the autobiographical memory loss? 2) Is there impairment of personal semantic and public semantic memory? 3) Is there evidence for focal retrograde amnesia? Methods 14 patients with TEA and 12 matched controls participated. We used a broad range of standard anterograde and remote memory tests to clarify the extent and nature of the remote memory deficits. In particular, we used the Autobiographical Interview (AI), which provides a more sensitive measure of autobiographical memory than previous instruments, together with tests measuring personal semantic and public semantic memory. Results Performance on standard tests of anterograde memory was normal. In contrast, there was a severe impairment of memory for autobiographical events, extending across the entire lifespan, providing evidence for the occurrence of “focal retrograde amnesia” in TEA. There was a milder impairment of personal semantic memory, most pronounced for midlife years. There were minor deficits of public semantic memory for recent decades. Conclusions These results may reflect subtle structural pathology in the medial temporal lobes or the effects of the propagation of epileptiform activity through the network of brain regions responsible for long-term memory.
Comparative Study of Short Term Load Forecasting Using Multilayer Feed Forward Neural Network With Back Propagation Learning and Radial Basis Functional Neural Network

The term load forecast refers to the projected load requirement using systematic process of defining load in sufficient quantitative detail so that important power system expansion decisions can be made. Load forecasting is necessary for economic generation of power, economic allocation between plants (unit commitment scheduling), maintenance scheduling and for system security such as peak load shaving by power interchange with interconnected utilities. With structural changes to electricity in recent years, there is an emphasis on Short Term Load Forecasting (STLF). STLF is the essential part of power system planning and operation. Basic operating functions such as unit commitment, economic dispatch, and fuel scheduling and unit maintenance can be performed efficiently with an accurate forecast. Short term load forecasting can help to estimate load flow and to make decisions that can prevent overloading. Timely implementations of such decisions lead to improvement of network reliability and to the reduced occurrences of equipment failures and blackouts. The aim of short term load forecasting is to predict future electricity demands based, traditionally on historical data and predicted weather conditions. Short term load forecasting in its basic form is a statistical problem, where in the previous load values (time series variables) and influencing factors (casual variables) are used to determine the future loads.
Energy detection of primary signals over η - μ fading channels

In this paper1, the performance analysis of an energy detector is exploited under the η-μ fading channel model. The received unknown signal at the energy detector is considered as the primary signal transmitted by a primary network user (e.g. cognitive radio network). This research is focused on derivation of the closed-form average detection probability over the η - μ fading channel model. Further, results are extended to two diversity reception cases such as maximal ratio combining (MRC) and square-law combining (SLC) techniques with independent fading channels. Detection performance is discussed with receiver operating characteristics (ROC) curves. Our analysis is validated by numerical and simulation results.
PERMA Adaptation of Well being measure to Turkish: Work of validity and reliability

Seligman? s ? well-being measure? called PERMA is a measure that lays off five components of a person? s level of being well. It was developed by Kern (2015). The measurement evaluates people? s level of well-being in five dimensions: They are as follows: (P: Positive and Negative emotions), (E: Engagement), (R: Relationships), (M: Meaning), (A: Accomplishment). The measurement consists of 23 articles. There is a ranging of grades from 0 to 10. The coefficiency of internal consistency of the measurement is . 82.The measurement of PERMA was applied on a group of university students. Some translation texts (from English to Turkish/from Turkish to English) were given to the students in the department of ELT and was intended to find out the meaningful positive corelations between low and high points (r=. 95, p
Computing Exponentials of Real Matrices Diagonalizable Over C

In this note, we consider the problem of computing the exponential of a real matrix. It is shown that if A is a real n × n matrix and A can be diagonalized over C, then there is a formula for computing e involving only real matrices. When A is a skew symmetric matrix, the formula reduces to the generalization of Rodrigues’s formula given in Gallier and Xu [1].
A remark about orthogonal matching pursuit algorithm

In this note, we investigate the theoretical properties of Orthogonal Matching Pursuit (OMP), a class of decoder to recover sparse signal in compressed sensing. In particular, we show that the OMP decoder can give $(p,q)$ instance optimality for a large class of encoders with $1\leq p\leq q \leq 2$ and $(p,q)\neq (2,2)$. We also show that, if the encoding matrix is drawn from an appropriate distribution, then the OMP decoder is $(2,2)$ instance optimal in probability.
Maritime information engine

Set the Chinese text sets into two classifications and determine whether the information is in the field of Chinese maritime by a two-classifier which is guided by multiple semantic. Eventually it gets Chinese maritime information set so that we can custom maritime information. We call this information system for the Chinese Marine engine. Experiments show that the Chinese Marine engine achieves good effects of custom the Chinese maritime information and it has a high practical value.