Miracle-dz/UniFAR-FTUs huggingface dataset:
Evaluation of the energy consumption and greenhouse gas emission related to Italian food c onsumption with an hybrid LCA­IO method

In the recent years the evaluation of environmental sustainability of lifestyles and consumption practices is getting a central role in European researches. Several analytical tools and methodologies are proposed in order to quantify the environmental burden of production and consumption. Environmental impact assessment methods are mainly divided in bottom-up (e.g. the Life Cycle Assessment LCA) and top-down (e.g. the Input-Output Analysis IOA), the first is focused on production processes and the second on the macroeconomic dimension of a community. Thus both of them are unsuitable to investigate at the level of practices and lifestyles. We discuss the advantage of an hybrid IOA-LCA method, which is developed to consider both positive aspects of bottom-up and top-down methodologies, in the evaluation of household consumption. This method has been applied just to the food sector as a test of the whole methodology.
Aneurysm Rupture Prediction Based on Strain Energy-CFD Modelling

This paper presents a Patient-Specific Aneurysm Model (PSAM) analyzed using Computational Fluid Dynamics (CFD). The PSAM combines the energy strain function and stress–strain relationship of the dilated vessel wall to predict the rupture of aneurysms. This predictive model is developed by analyzing ultrasound images acquired with a 6–9 MHz Doppler transducer, which provides real-time data on the arterial deformations. The patient-specific cyclic loading on the PSAM is extrapolated from the strain energy function developed using historical stress–strain relationships. Multivariant factors are proposed to locate points of arterial weakening that precede rupture. Biaxial tensile tests are used to calculate the material properties of the artery wall, enabling the observation of the time-dependent material response in wall rupture formation. In this way, correlations between the wall deformation and tissue failure mode can predict the aneurysm’s propensity to rupture. This method can be embedded within the ultrasound measures used to diagnose potential AAA ruptures.
The Impact of the COVID-19 Pandemic on the Assessment of Healthcare and Anxiety Disorders in Patients with Chronic Diseases

(1) Background: We compared the impact of the COVID-19 pandemic on the functioning and mental health of chronically ill patients, namely those with hemodialysis (HD) and diabetes (DM). (2) Methods: We used a questionnaire to collect the medical data and the Generalized Anxiety Questionnaire (GAD-7) to measure the mood status. (3) Results: In both groups, a similar percentage of patients had a past COVID-19 infection and similar opinions about pandemic-related inconveniences. The most significant limitations of the study included mask wearing and the restriction of social contact. Mental disorders were significantly more frequently reported in the DM group. Sleep problems were found in approximately 30% of patients. Approximately 20% of patients in both groups declared that the pandemic had negatively affected the quality of their sleep. The mean score of the GAD-7 scale in the HD group did not differ according to gender. In the group of DM patients, a significant difference was observed between men and women, with women scoring higher compared to men. In both groups, the percentage of patients with GAD-7 scores > 5, > 10 and > 15 did not differ significantly. (4) Conclusions: In both groups, chronically ill patients reported anxiety disorders with similar frequency. In the DM group, more severe anxiety disorders were found in women. Mental disorders were significantly more prevalent in DM patients. It seems that HD patients coped better with the psychological aspects of pandemic-related stress and limitations.
Geologic significance of microboring fungi and algae in Carolina shelf sediments

ABSTRACT Carbonate components of relict continental margin sediments off North and South Carolina show abundant evidence of microborings related to endolithic fungi and algae. Microborings were observed in bottom sediments collected from 165 sites ranging in depth from the intertidal to 780 meters. Forty-two of these samples were fixed in buffered formaldehyde to preserve endolithic organisms which were subsequently isolated for study through decalcification of skeletal substrates. Plastic impregnated thin sections and etched slabs, the latter revealing three dimensional models of boring networks, were also used to distinguish three main types of microborings: a) fungi, 1-4 microns in diameter, b) a septate green alga, 10 microns in diameter, and c) a diagnostic siphonaceous green alga, 15-20 icrons in diameter. Of these endolithic plants, fungi were the most abundant as well as most widespread. A distinctive, siphonaceous green alga defined three linear bands of highly bored sediments believed to reflect nearshore zones of high algal boring activity. The innermost zone, extending from the present day intertidal to depths of approximately 25 meters, is considered to be presently active; the outer two zones on the shelf are interpreted as marking relict shoreline positions associated with lower sea level stands. In situ organic erosion by microboring organisms is believed to be an important source of carbonate fines in Carolina shelf sediments. Molluscan components are being selectively attacked and removed from the carbonate fraction through the activity of endolithic fungi and algae. The relative abundance of carbonates in Carolina shelf sediments is therefore believed to be not only related to skeletal productivity and degree of dilution by clastics, but also to the degree of organic erosion to which sediments have been subjected.
Infrared spectrum for derivative steroid with potential to treat breast cancer

—This study applies Density Functional Theory (DFT), using the B3LYP functional, and via ab initio Restrict Hartree-Fock (RHF) methods, to study the infrared spectrum of steroid 17-Iodo-androst-16-ene. The spectrum was obtained via computational methods ab initio RHF and DFT. Optimization of molecular structure via UFF (Universal Force Field), followed by PM3 (Parametric Method 3), with geometric optimization, obtaining the spectrum of other basis sets of steroid 17-Iodo-androst-16-ene. The study this steroid was chosen because it can could act as aromatase enzyme inhibitors and this phenomenon could be translated as good compounds to treat breast cancer. The B3LYP functional always presents the lowest thermal energy than the RHF in all calculated bases, however the RHF always presents the highest Entropy than the B3LYP, in all the calculated basis sets. The normalized spectrum calculated in the B3LYP/SVP functional/basis set have harmonic frequency with peaks 3,241.83 cm − 1 , 100% and 3,177.535 cm − 1 at 43.304% absorbance. The study has so far been limited to computational methods compatible with the theory of quantum chemistry.
Bacterial Associations with Weathering Minerals at the Regolith-Bedrock Interface, Luquillo Experimental Forest, Puerto Rico

Microbe-mineral associations in regolith overlying granodiorite bedrock (4.6–4.9 m depth) from the Luquillo Experimental Forest, Puerto Rico, were imaged with confocal scanning laser microscopy at a novel scale of 400X magnification. After adding BacLight™ stain, proportionally more surface area of minerals (quartz, biotite, and mixed opaque kaolinite/goethite) emitted fluorescence from cell-impermeant propidium iodide than from cell-permeant SYTO 9, which suggested greater coverage of minerals by extracellular DNA or DNA in non-intact cells than by intact cells. Microscopic observations of predominantly non-intact cell material in deep saprolite were consistent with the abundance of rRNA sequences related to heterotrophic bacteria in clone libraries prepared from community DNA. A few sequences were affiliated with bacteria recognized to produce siderophores, oxidize Fe(II), or fix N2. Bacterial DNA in deep regolith from two boreholes 1.5 m apart yielded libraries with high diversity and taxa specific for each borehole. Supplemental materials are available for this article. Go to the publisher's online edition of Geomicrobiology Journal to view the free supplemental files.
PUBLISHED VERSION

Background: Frost is an important abiotic stress that limits cereal production in the temperate zone. As the most frost tolerant small grain cereal, rye (Secale cereale L.) is an ideal cereal model for investigating the genetic basis of frost tolerance (FT), a complex trait with polygenic inheritance. Using 201 genotypes from five Eastern and Middle European winter rye populations, this study reports a multi-platform candidate gene-based association analysis in rye using 161 single nucleotide polymorphisms (SNPs) and nine insertion-deletion (Indel) polymorphisms previously identified from twelve candidate genes with a putative role in the frost responsive network. Results: Phenotypic data analyses of FT in three different phenotyping platforms, controlled, semi-controlled and field, revealed significant genetic variations in the plant material under study. Statistically significant (P < 0.05) associations between FT and SNPs/haplotypes of candidate genes were identified. Two SNPs in ScCbf15 and one in ScCbf12, all leading to amino acid exchanges, were significantly associated with FT over all three phenotyping platforms. Distribution of SNP effect sizes expressed as percentage of the genetic variance explained by individual SNPs was highly skewed towards zero with a few SNPs obtaining large effects. Two-way epistasis was found between 14 pairs of candidate genes. Relatively low to medium empirical correlations of SNP-FT associations were observed across the three platforms underlining the need for multi-level experimentation for dissecting complex associations between genotypes and FT in rye. Conclusions: Candidate gene based-association studies are a powerful tool for investigating the genetic basis of FT in rye. Results of this study support the findings of bi-parental linkage mapping and expression studies that the Cbf gene family plays an essential role in FT.
Corruptive intention and anti-citizenship behavior: A study of the impact of workplace dissatisfaction among personnel in the Cameroonian public health care sector

This study focuses on the sociocognitive processes that generally affect actors in the public administration and undermine their values, ethics, and the sense of providing a free and equitable public service, as recognized in administrative bureaucracies. We started with the following research question: What are the direct underlying determinants of corruptible behavior among public health personnel? Through a dual analysis of correlation and mediation using structural equation modeling, a confirmatory figure was presented, demonstrating the mediating effect (Hayes, 2018) of workplace distress on Corruptive Behavioral Intention (CBI) on one hand, and Organizational Citizenship Behavior (OCB) on the other.
Complex problem solving : the European perspective

Contents: Preface. Part I: Introduction. P.A. Frensch, J. Funke, Definitions, Traditions, and a General Framework for Understanding Complex Problem Solving. A. Buchner, Basic Topics and Approaches to the Study of Complex Problem Solving. D. Dorner, A.J. Wearing, Complex Problem Solving: Toward a (Computersimulated) Theory. Part II: General Topics in the Study of Complex Problem Solving. B. Brehmer, Feedback Delays in Complex Dynamic Decision Tasks. D.C. Berry, D.E. Broadbent, Implicit Learning in the Control of Complex Systems. O. Huber, Complex Problem Solving as Multistage Decision Making. Part III: The Differential Approach to Complex Problem Solving. J.F. Beckmann, J. Guthke, Complex Problem Solving, Intelligence, and Learning Ability. J.F. Krems, Cognitive Flexibility and Complex Problem Solving. U. Funke, Using Complex Problem Solving Tasks in Personnel Selection and Training. Part IV: Methodological Issues in Research on Complex Problem Solving. J. Funke, Experimental Research on Complex Problem Solving. R.H. Kluwe, Single Case Studies and Models of Complex Problem Solving. Part V: Conclusions. R.J. Sternberg, Expertise in Complex Problem Solving: A Comparison of Alternative Conceptions.
Application of Lagrangian approach to generate P-I diagrams for RC columns exposed to extreme dynamic loading

The interaction between blast load and structures, as well as t he interaction among structural members may well affect the structural response and damages. Therefore, it is necessary to analyse more realistic reinforced concrete structures in order to gain an extensive knowledge on the possible structural response under blast load effect. Among all the civilian structures, columns are considered to be the most vulnerable to terrorist threat and hence detailed investigation in the dynamic response of these structures is essential. Therefore, current research examines the effect of blast loads on the reinforced concrete columns via development of Pressure-Impulse (P-I) diagrams. In the finite element analysis, the level of damage on each of the aforementioned RC column will be assessed and the response of the RC columns when subjected to explosive loads will also be identified. Numerical models carried out using LS-DYNA were compared with experimental results. It was shown that the model yields a reliable prediction of damage on all RC columns. Validation study is conducted based on the experimental test to investigate the accuracy of finite element models to represent the behaviour of the models. The blast load application in the current research is determined based on the Lagrangian approach. To develop the designated P-I curves, damage assessment criteria are used based on the residual capacity of column. Intensive investigations are implemented to assess the effect of column dimension, concrete and steel properties and reinforcement ratio on the P-I diagram of RC columns. The produced P-I models can be applied by designers to predict the damage of new columns and to assess existing columns subjected to different blast load conditions.
Construction of a ﬂocculent brewer’s yeast strain secreting Aspergillusniger b -galactosidase

One way of improving heterologous protein production is to use high cell density systems, one of the most attractive being the ﬂocculating yeast production system. Also, lactose is available in large amounts as a waste product from cheese production processes. The construction of ﬂocculent and non-ﬂocculent brewer’s yeast strains secreting b -galactosidase and growing on lactose is presented. A plasmid was constructed coding for an extracellular b -galactosidase of Aspergillus niger and having, as selective marker, the yeast CUP1 gene conferring resistance to copper. This selective marker allows for the transformation of wild-type yeasts. This work represents an important step towards the study of heterologous protein secretion by ﬂocculent cells.
Educación Física y hábitos de vida activa: percepciones de los adolescentes y relación con el abandono deportivo

The aim of the research was to know the adolescents? perceptions about Physical Education and lifestyle physical activity regarding sport dropout. For this objective, a questionnaire was designed to study the perception of 164 secondary students (3o Secondary Education, 78 male and 88 female, aged between 14 and 15) of four high schools of Castilla-La Mancha. The results showed a high appreciation of PE. However, the findings revealed that most teachers did not improve students? motivation in the corresponding subject. Also, results showed gender differences as regards practice, with lower values in the case of girls. An important number of girls with sport dropout justified this behavior arguing they did not practice an appropriate sport for women
Are There Any Relationship Between Tech Firm's Stock Prices and Cryptocurrency's Values?: A Pre and Post Pandemic Period Analysis

This study was conducted to investigate the relationship between the stock prices of technology companies traded on the Nasdaq stock exchange and the values of cryptocurrencies in different periods. Regression and correlation analysis were used in the study. According to the study findings; It is possible to say that there is a positive and strong relationship between technology company stock prices and the values of cryptocurrencies during and after the COVID-19 period. However, no significant relationship was found before the COVID-19. It is evaluated that this situation can be explained by the first liquidity abundance applied in the COVID-19 and post-COVID-19 period and the FED policies towards inflationary pressures experienced at the global level afterwards.
The grapevine homeobox gene VvHB58 in�uences seed and fruit development through multiple hormonal signaling pathways

Background: The homeobox transcription factor has a diversity of functions during plant growth and development process. Previous transcriptome analyses of seed development in grape hybrids suggested that speci�c homeodomain transcription factors are involved in seed development in seedless cultivars. However, the molecular mechanism of homeobox gene regulating seed development in grape is rarely reported. Results: Here, we report that the grapevine VvHB58 gene, encoding a homeodomain-leucine zipper (HD-Zip I) transcription factor, participates in regulating fruit size and seed number. The VvHB58 gene was differentially expressed during seed development between seedless and seeded cultivars. Subcellular localization assays revealed that the VvHB58 protein was located in the nucleus. Transgenic expression of VvHB58 in tomato led to loss of apical dominance, a reduction in fruit pericarp expansion, reduced fruit size and seed number, and larger endosperm cells. Analysis of the cytosine methylation levels within the VvHB58 promoter indicated that the differential expression during seed development between seedless and seeded grapes may be caused by different transcriptional regulatory mechanisms rather than promoter DNA methylation. Measurements of �ve classic endogenous hormones and expression analysis of hormone-related genes between VvHB58 transgenic and nontransgenic control plants showed that expression of VvHB58 resulted in signi�cant changes in auxin, gibberellin and ethylene signaling pathways. Additionally, several DNA methylation-related genes were expressed differentially during seed development stages in seedless and seeded grapes, suggesting changes in methylation levels during seed development may be associated with seed abortion. Conclusion: VvHB58 has a potential function in regulating fruit and seed development by impacting multiple hormonal pathways. These results expand understanding of homeodomain transcription factors and potential regulatory mechanism of seed development in grapevine, and provided insights into molecular breeding for grapes.
Deciphering the role of codon usage bias on gene expression and pathogen colonization in Crocus sativus

Codon usage bias (CUB) is a ubiquitous phenomenon perseveres in genome of all the organisms. It impinges the gene expression and other genetic intricacies within a genome. The present study explicates the pattern of codon usage in the protein coding sequence of Crocus sativus and its relation with gene expression. Gene expression analysis in C. sativus showed genes with high expression had a preference of G base at third position. CUB had an inverse relation with gene expression. Coding sequences with ENC < 50 had low FPKM value while low codon bias group (ENC > 50) possessed high FPKM value. The low tAI values showed the low translation e�ciency of genes in C. sativus. The non-signicant MELP and ENC correlation analysis suggested that expression of genes might not be associated with CUB. ENC and PR-2 plot revealed mutation pressure and natural selection played role in shaping CUB. However, neutrality plot conclusively depicted the dominance of natural selection in regulating the con�guration of codons in all three species. In addition, the role of CUB regarding the predilection of fungal pathogens Aspergillus fumigatus and Fusarium oxysporum towards host plant C. sativus has also been expounded. We found a similar trend of codon usage pattern operative in plant and fungal pathogens as both the fungal pathogens and host plant showed similar GC rich genomic content as well as preference for GC ending codons at third codon position. This concurrence might be attributed for the colonization of fungal pathogens in C. sativus. Overall, different CUB indices re�ected a weak codon bias in the C. sativus, F. oxysporum and A. fumigatus genome.
The Expression of Angiogenesis Genes is Related to Immune Microenvironment and Prognosis of Lung Adenocarcinoma

Objective: Lung adenocarcinoma (LC), the main type of non-small cell lung cancer, has a 5-year survival rate of only 14.6%. Tumor angiogenesis is the primary factor leading to the progression of LC. This study aimed to discuss the role of angiogenesis-related genes(ARGs) in the development and diagnosis of LC. Methods: Clinical and transcriptomic data of LC patients were downloaded from TCGA and GEO databases and divided into training cohorts and validation cohorts. Combined with the ARGs of the Molecular Signatures Database, cluster analysis was performed to identify new clusrer subgroups. Enrichment analyses were performed to elucidate the underlying mechanisms of subpopulation differences. MCPCounter, CIBERSORT and xCell analysis was used to determine the tumor immune microenvironment (TIM) and the immune status of identi�ed subgroups. Lasso algorithm and multivariate Cox regression analysis were used to construct the prognostic risk model, and combined with the clinical information of patients with LC to verify the effectiveness of the risk model. Results: We identi�ed 2 cluster subgroups that could signi�cantly predict differential survival based on LC survival prognostic genes and ARGs. Among them, cluster 2 showed a better prognosis and was associated with a high immune score, a high abundance of immune in�ltrating cells, and a relatively high immune status. Enrichment analysis revealed that DEGs between the two subgroups were mainly enriched in angiogenesis and immune related pathways. Combined with clinical features, higher risk scores were positively associated with LC worsening of disease progression, predicting poor survival. The validation cohort GSE68465 corroborates the validity of the risk model. Conclusion: The abnormal expression of ARGs is closely related to the TIM of LC patients. The ARG risk model we constructed can be used to accurately predict the survival prognosis of LC.
Female College Students' Perceptions on the Internet Use for Reproductive Health Information

This study aims to explore the factors related to young women's Internet use for reproductive health information, specifically focusing on female college students. The research model is based on the Health Belief Model (HBM) and the Theory of Planned Behavior (TPB). A convenience sample of female college students who have recently used the Internet for reproductive health information will participate in an online survey. The survey will collect demographic information, background details on Internet use for reproductive health, and perceptions of reproductive health behaviors. Data analysis will examine correlations among the perceptions and their association with the intention to continue using the Internet for reproductive health information. The findings will contribute to understanding female college students' influential factors and information behaviors, informing the development of educational programs, intervention strategies, and online resources to improve reproductive health outcomes and empower young women.