Miracle-dz/UniFAR-FTUs huggingface dataset:
Business model analysis for spectrum sharing with the spectrum broker

This work presents the business model analysis for the spectrum sharing mechanism in the cellular network, based on the spectrum broker entity. We identify key modifications to the market and business relations, required for the spectrum sharing scenario implementation, with the focus on the network operator stimulation. Due to the fact, that the spectrum usage in the current markets is subject to various constraints coming from regulatory, standardization bodies, as well as hardware limitations point of view, various market players and their positions within described spectrum sharing scenarios are considered and analyzed. This document captures analysis of novel spectrum sharing technique on the service delivery chain, discovers new business opportunities, discuss the influence on the strategy of the current key market players. Finally, cost aspects are analyzed, where the required investments are identified for the described spectrum sharing scenario.
Einführung in die Thematik Achtsamkeit und Akzeptanz in der Psychotherapie

Der vorliegende Artikel fuhrt in den Themenschwerpunkt “Achtsamkeit und Akzeptanz in der Psychotherapie” ein. Die Begriffe werden zunachst definiert und wesentliche Anwendungen von Achtsamkeit und Akzeptanz in der Psychotherapie vorgestellt. Es wird dargelegt, dass sich in verschiedenen psychotherapeutischen Traditionen Prinzipien finden lassen, die Ahnlichkeiten zu Achtsamkeit aufweisen. Bei Ansatzen, die Achtsamkeit explizit aufgreifen, lassen sich achtsamkeitsinformierte und achtsamkeitsbasierte Ansatze unterscheiden: Wahrend achtsamkeitsinformierte Ansatze einzelne Prinzipien der Achtsamkeit in die Behandlung integrieren, betrachten achtsamkeitsbasierte Ansatze diese als ihr wesentliches Agens. Sowohl achtsamkeitsinformierte als auch achtsamkeitsbasierte Ansatze werden im vorliegenden Artikel in ihren Grundzugen vorgestellt.
Increasing Phenotypic and Genetic variations in Hyperactivity/Inattention Problems from Age 3 to 13 Years: A Cross-Sectional Twin Study

A twin design was used to examine the developmental nature of genetic, environmental, and phenotypic variations in hyperactivity and inattention problems (HIP). Mothers of 662 complete pairs of twins (273 monozygotic [MZ] pairs and 389 dizygotic [DZ] pairs) aged from 3 to 13 years (mean [SD] age = 8.3 [2.9] years) responded to the items of the HIP scale of the Strengths and Difficulties questionnaire via a telephone interview. Maximum likelihood MZ and DZ twin correlations in the total sample were 0.47 (95% CI: 0.37–0.55) and −0.01 (95% CI: −0.11–0.09). A standard univariate model incorporating age as a modifier was applied to the raw data. Results of model-fitting analyses showed that the phenotypic variation of HIP monotonically increased from age 3 to age 12 and that this increase was completely due to an increase in genetic variance, suggesting that it is genes that expand individual difference in ADHD symptoms with age during childhood. Child-specific environmental variance was constant during this age period. In terms of relative influences, total genetic factors increased from 33% (95% CI: 27–44%) at age 3 to 51% (95% CI: 28–71%) at age 13 and this increase was accompanied by a decrease in relative influences of child-specific environmental factors from 67% (95% CI: 56–73%) at age 3 to 49% (95% CI: 29–72%) at age 13. These estimates of genetic influences were somewhat lower than those found in most twin studies of ADHD symptoms. However, the increasing trend of genetic influences with age during childhood was consistent with the results of a recent meta-analysis of ADHD symptoms.
Distinguishing Sequences for Distributed Testing: Preset Distinguishing Sequences

This paper concerns the problem of testing from a finite state machine (FSM) $M$ modelling a system that interacts with its environment at multiple physically distributed interfaces, called ports. We assume that the distributed test architecture is used: there is a local tester at each port, the tester at port $p$ only observes events at $p$ and the testers do not interact during testing. This paper formalizes the notion of an adaptive test strategy and what it means for an adaptive test strategy to be controllable. We provide algorithms to check whether a global strategy is controllable and to generate a controllable adaptive distinguishing sequence (ADS). We prove that controllable ADS existence is PSPACE-Hard and that the problem of deciding whether $M$ has a controllable ADS with length $\ell $ is NP-Hard. In practice, there is likely to be a polynomial upper bound on the length of ADS in which we are interested and for this case the decision problem is NP-Complete.
Press Secretaries, Journalists, and Editors: Shaping Local Congressional News Coverage

The news media plays a key role in American democracy, often serving as the primary means by which voters learn about their elected representatives. However, the news media varies in its coverage of representatives, presenting voters with more frequent and favorable information about some House members than others, which may in turn influence voters' decisions at the polls. Although many scholars have examined the determinants of congressional news coverage, few have focused on the role of the actors who perhaps exert the most direct effect on such coverage: congressional press secretaries, journalists, and editors. In this study, I explore the influence of these actors on the tone and frequency of local congressional news coverage. I rely on data from two sources: (a) a content analysis of newspaper coverage of 100 representatives during the month prior to the 2006 election and (b) in-depth interviews with 51 congressional press secretaries and 22 journalists. These sets of data illustrate the important roles of both newspaper staff and congressional press secretaries in shaping the coverage House members receive. I conclude by discussing the implications of the findings for U.S. representatives and their constituents.
Mechanistic Insight of Probiotics Derived Anticancer Pharmaceuticals: A Road Forward for Cancer Therapeutics

ABSTRACT Probiotics are living organisms that confer health benefits when administered in adequate amounts. Probiotics are continuously being explored for their different health beneficiary activities. Anticancer activity is one of the most important benefits both from a preventive and therapeutic point of view. Though not many studies have been conducted to date in this area, a number suggest using laboratory animal models and different cell lines that there may be a mechanistic basis for the anticancer effects of probiotics and require more scientific justification and clinical trials. Most studies of probiotics are conducted for colon cancer associated with inflammatory bowel disease. Studies are also being extended to other types of cancer in different cell lines. This review summarizes studied probiotics considered for treatment of colon cancer and some other cancers (in cancer cell lines) and also proposed mechanism how probiotics are inhibiting cancer growth along with some challenges and future perspectives.
Modeling Dynamics of Online Video Popularity

Video popularity (measured by view count) over time is an essential reference for both online video providers and users. According to state-of-the-art works, video popularity is useful for system optimization, load generation, video caching, and video recommendation. Thus, deeper understanding of video popularity evolution is very helpful for improving video service quality and providers' operating efficiency. The core question to be explored in this paper is what key factors govern online video popularity evolution? Through collaboration with our industry partner, Tencent Video, we obtain historical data of video view counts over a period of time, and observe their patterns. We then propose a stochastic fluid model, named as EvoModel, which captures two processes giving rise to different evolution patterns of a given video: (a) the information spreading process and (b) the user reaction process. The driving forces for process (a) can be either via recommendation from the system directly, or word-of-mouth; the extent of the spread is governed by the intrinsic popularity of the video. The factor affecting the second process can be modeled by a user reaction rate. These processes together determine different video popularity evolution patterns. We validate our model by fitting the historical data obtained from a real-world system. Furthermore, we discuss the feasibility of estimating model parameters and predicting popularity.
Position Statement of the Chinese Diabetes Society regarding stem cell therapy for diabetes *

Diabetes is a devastating disease that affects both the physical and mental health of millions of people worldwide, with prolonged hyperglycemia responsible for a variety of chronic complications. Type 1 diabetes results from an autoimmune attack against islet b-cells, which itself causes absolute insulin deficiency; type 2 diabetes is characterized by both insulin resistance and subsequent progressive decline in b-cell function, resulting in relative insulin deficiency. Patients with type 1 diabetes require daily insulin injections to survive and most people with type 2 diabetes over a prolonged period of time also eventually require exogenous insulin to control high blood glucose levels. However, insulin therapy does not ensure ideal blood glucose control and, in addition to the inconvenience and pain associated with injections, can cause side effects such as hypoglycemia and weight gain. Thus, insulin therapy is not the ideal method for the treatment of diabetes. Under normal conditions in humans, islet b-cells automatically regulate insulin secretion according to blood glucose levels and maintain glucose homeostasis without the risk of hypoglycemia. In contrast, b-cell is considerably impaired in diabetes. Therefore re-establishing a functional b-cell mass in vivo in diabetics may be the ideal for the treatment of the condition.
Pneumonia and urinary tract infection after acute ischaemic stroke: a tertiary analysis of the GAIN International trial

The third most common stroke complication is infection. We studied the rates of aspiration pneumonia and urinary tract infection (UTI), their risk factors and their effect on outcome in the 1455 Glycine Antagonist (Gavestinel) in Neuroprotection (GAIN) International patients with ischaemic stroke. Forward stepwise logistic regression and Cox proportional hazards modelling identified baseline factors that predicted events and the independent effect of events up to day 7 on poor stroke outcome at 3 months in patients alive at day 7, after correcting for prognostic factors. Higher baseline National Institute of Health Stroke Scale (NIHSS) and age, male gender, history of diabetes and stroke subtype predicted pneumonia, which occurred in 13.6% of patients. Female gender and higher baseline NIHSS and age predicted UTI, which occurred in 17.2% of patients. Pneumonia was associated with poor outcome by mortality (hazard ratio, 2.2; 95% confidence interval, 1.5–3.3), Barthel index (<60) (odds ratio, 3.8; 2.2–6.7), NIHSS (4.9; 1.7–14) and Rankin scale (≥2) (3.4; 1.4–8.3). UTI was associated with Barthel index (1.9; 1.2–2.9), NIHSS (2.2; 1.2–4.0) and Rankin scale (3.1; 1.6–4.9). Pneumonia and UTI are independently associated with stroke poor outcome. Patients with identified risk factors must be closely monitored for infection.
Oxidative Imbalance and Anxiety Disorders

The oxidative imbalance appears to have an important role in anxiety development. Studies in both humans and animals have shown a strong correlation between anxiety and oxidative stress. In humans, for example, the increased malondialdehyde levels and discrepancies in antioxidant enzymes in erythrocytes have been observed. In animals, several studies also show that anxiety-like behavior is related to the oxidative imbalance. Moreover, anxiety-like behavior can be caused by pharmacological-induced oxidative stress. Studies using knockout or overexpression of antioxidant enzymes have shown a relationship between anxiety-like behavior and oxidative stress. Related factors of oxidative stress that could influence anxious behavior are revised, including impaired function of different mitochondrial proteins, inflammatory cytokines, and neurotrophic factors. It has been suggested that a therapy specifically focus in reducing reactive species production may have a beneficial effect in reducing anxiety. However, the neurobiological pathways underlying the effect of oxidative stress on anxiety symptoms are not fully comprehended. The challenge now is to identify the oxidative stress mechanisms likely to be involved in the induction of anxiety symptoms. Understanding these pathways could help to clarify the neurobiology of the anxiety disorder and provide tools for new discovery in therapies and preventive strategies.
Iris biometrie: Is the near-infrared spectrum always the best?

Previous work on iris recognition focused on either Visible Light (VL), Near-Infrared (NIR) imaging or the fusion between them. However, limited numbers of works have compared the iris biometric performance under both VL and NIR spectrum using images taken from the same subject. In this paper, we explore the differences in iris recognition performance across the VL and NIR spectrum. In addition, we investigate the possibility of cross-channel matching between the VL and NIR imaging. We carried out our experiments on the UTIRIS database which contains iris images taken under both the VL and NIR spectrum for the same subject. This paper is amongst the first studies which compares the performance of iris biometric under the NIR and VL spectrum and produces comparative experiments between these types of data. Experimental results indicate that the VL and NIR images provide complementary features for the iris pattern and their fusion improves the recognition performance. In addition, the experiments indicate that cross-channel matching between VL and NIR images is feasible.
Direct Manipulation on the Virtual Workbench: Two Hands Aren't Always Better Than One

This paper reports on the investigation of the differential levels of effectiveness of various interaction techniques on a simple rotation and translation task on the virtual workbench. Manipulation time and number of collisions were measured for subjects using four device sets (unimanual glove, bimanual glove, unimanual stick, and bimanual stick). Participants were also asked to subjectively judge each device's effectiveness. Performance results indicated a main effect for device (better performance for users of the stick(s)), but not for number of hands. Subjective results supported these findings, as users expressed a preference for the stick(s).
Massive Cerebral Infarction with Severe Brain Swelling: A CLINICOPATHOLOGICAL STUDY

All cases of acute supratentorial cerebral infarction which came to postmortem examination over the past 10 years at the Philadelphia General Hospital were reviewed. Of a total of 353 such cases, 45 showed severe brain swelling. Seventy-eight percent of these 45 patients died within seven days of the acute infarction. The rapidly fatal outcome appeared to be directly related to the acute brain swelling with transtentorial herniation and brain-stem edema or hemorrhage. In those patients who survived longer than one week following onset of the ictus (22%), clinical and anatomic findings suggested that increased intracranial pressure probably did not develop until later in the course of the illness. A second massive infarct was probably superimposed upon an earlier one and produced the acute brain swelling noted at the time of postmortem examination. Complicating visceral diseases were more common in this group and seemed to contribute to death in the majority of these patients. Although it has been established that a large cerebral infarct may produce sufficient brain swelling and simulate an acutely expanding lesion, this is not widely recognized as playing an important part in determining the patient's clinical outcome. The role of increased intracranial pressure resulting from acute brain swelling should not be overlooked in the management of patients with severe strokes.
Perfluoropolyether phosphate: skin exfoliation after a topical pre‐treatment, TEWL and skin elasticity, by in‐vivo non‐invasive methods

Glycolic acid (GA) and other alpha‐hydroxyacids (AHAs) are common ingredients of products designed to accelerate exfoliation of the skin. It is known that acidic pHs are essential in order to increase the efficacy of AHA‐based products. The formulator is, therefore, obliged to achieve a difficult balance between performance (skin exfoliation) and risks (skin irritation). In order to overcome this problem, many common organic acids, and combinations of them, have been proposed, with marginal improvements. The need for a new chemistry, in order to achieve better results, was evident, particularly from the point of view of safety. We decided, therefore, to investigate the efficacy of perfluoropolyether (PFPE) phosphate, a new acidic material, already proposed for lowering the pH without increasing skin irritation. Two gels containing PFPE phosphate at different pH values (3 and 7), an acidic gel containing GA at pH 3, and a neutral gel, without an active compound, were applied on 20 healthy volunteers and evaluated with regard to effects on the skin:
Analytical performance and diagnostic accuracy of immunometric assays for the measurement of plasma B-type natriuretic peptide (BNP) and N-terminal proBNP.

Over the last 5 years, several immunoassay methods for the measurement of B-type natriuretic peptide (BNP) and N-terminal proBNP (NT-proBNP) became commercially available. Recent studies have confirmed the clinical usefulness of measurements of these cardiac natriuretic peptides for the prognostic stratification of patients with congestive heart failure, for the detection of left ventricular systolic and/or diastolic dysfunction, and for the differential diagnosis of dyspnea (1)(2)(3)(4). However, to answer the most urgent requests of current clinical practice and to allow widespread use of BNP and NT-proBNP assays, some key issues had to be solved, such as increasing the sensitivity, precision, and experimental practicability (5). The aim of the present study was to evaluate and compare the analytical and clinical performance of five commercial natriuretic peptide immunoassays. Throughout this report, the values in healthy individuals and patients are reported as the range, median, and 25th and 75th percentiles. We enrolled 172 healthy adults (89 women and 83 men; age range, 16–73 years; median age, 49.0 years; 25th percentile, 38 years; 75th percentile, 58 years). All participants were nonobese (body mass index, 19.4–27.6 kg/m2, 24 kg/m2, 22.8 kg/m2, and 25.6 kg/m2), normotensive (diastolic blood pressure, 60–85 mmHg, 70 mmHg, 70 mmHg, and 80 mmHg; systolic blood pressure, 90–140 mmHg, 120 mmHg, 102.5 mmHg, and 124.5 mmHg), and free from acute or chronic diseases. All participants had main plasma indices (including creatinine, urea nitrogen, glucose, uric acid, albumin, enzymes, electrolytes, and hemoglobin) within the appropriate reference intervals, and normal erythrocyte and leukocyte counts …
A Trimodal Behavioral Conceptualization of Clinical Pain

A trimodal behavioral conceptualization of pain is outlined in the current article. It proposes that pain should be viewed as an interacting cluster of gross motor, cognitive, and physiological responses. Such a conceptual system is thought to contain the basic properties needed to incorporate current divergent views of pain held by medical and behavior science into a common conceptual framework.
A classification of emotion and gender using approximation image Gabor local binary pattern

Gender classification and emotion detection plays an important role in the areas security. Gender classification and emotion detection aids in identification of a person by recognizing its gender (male/female) with their emotions (happy/sad) from the face image only. Individual works has been done in the Gender classification and emotion detection fields but not together. In this paper, we proposed a system to do detection of emotion and gender simultaneously for a specific face image. In this paper AIGLBP (Approximation image Gabor local binary pattern) is applied for feature extraction and SVM is used for classification. The number of experiments is initiated on a standard face image databases taken in controlled (FERET and INDIAN FACE) environment. The experimental results demonstrate that the proposed system is effective enough to give high performance in terms of speed and accuracy.
Potato Tuber Induction is Regulated by Interactions Between Components of a Tuberigen Complex

Photoperiod-regulated flowering and potato tuber formation involve leaf-produced mobile signals, florigen and tuberigen, respectively. The major protein component of florigen has been identified as the FLOWERING LOCUS T (FT) protein. In rice, an FT-like protein, Heading date 3a (Hd3a), induces flowering by making the florigen activation complex (FAC) through interactions with 14-3-3 and OsFD1, a rice FD-like protein. In potato, StSP6A, an FT-like protein, was identified as a major component of tuberigen. However, the molecular mechanism of how StSP6A triggers tuber formation remains elusive. Here we analyzed the significance of the formation of a complex including StSP6A, 14-3-3 and FD-like proteins in tuberization. Yeast two-hybrid, bimolecular fluorescence complementation and in vitro pull-down assays showed that StSP6A and StFDL1, a potato FD-like protein, interact with St14-3-3s. StSP6A overexpression induced early tuberization in a 14-3-3-dependent manner, and suppression of StFDL1 delayed tuberization. These results strongly suggest that an FAC-like complex, the tuberigen activation complex (TAC), comprised of StSP6A, St14-3-3s and StFDL1, regulates potato tuber formation.
Contribution of Macrophages to Enhanced Regenerative Capacity of Dorsal Root Ganglia Sensory Neurons by Conditioning Injury

Although the central branches of the dorsal root ganglion (DRG) sensory neurons do not spontaneously regenerate, a conditioning peripheral injury can promote their regeneration. A potential role of macrophages in axonal regeneration was proposed, but it has not been critically addressed whether macrophages play an essential role in the conditioning injury model. After sciatic nerve injury (SNI) in rats, the number of macrophages in DRGs gradually increased by day 7. The increase persisted up to 28 d and was accompanied by upregulation of inflammatory mediators, including oncomodulin. A macrophage deactivator, minocycline, reduced the macrophage number and expressions of the inflammatory mediators. Molecular signatures of conditioning effects were abrogated by minocycline, and enhanced regenerative capacity was substantially attenuated both in vitro and in vivo. Delayed minocycline infusion abrogated the SNI-induced long-lasting heightened neurite outgrowth potential, indicating a role for macrophages in the maintenance of regenerative capacity. Intraganglionic cAMP injection also resulted in an increase in macrophages, and minocycline abolished the cAMP effect on neurite outgrowth. However, conditioned media (CM) from macrophages treated with cAMP did not exhibit neurite growth-promoting activity. In contrast, CM from neuron–macrophage cocultures treated with cAMP promoted neurite outgrowth greatly, highlighting a requirement for neuron–macrophage interactions for the induction of a proregenerative macrophage phenotype. The growth-promoting activity in the CM was profoundly attenuated by an oncomodulin neutralizing antibody. These results suggest that the neuron–macrophage interactions involved in eliciting a proregenerative phenotype in macrophages may be a novel target to induce long-lasting regenerative processes after axonal injuries in the CNS.