Miracle-dz/UniFAR-FTUs huggingface dataset:
Analysis of Magnetoencephalography based on symbolic transfer entropy

In this paper, we symbolize two kinds of different channels of Magnetoencephalography(MEG) and analyze their coupling relationship using symbolic transfer entropy algorithm. We record MEG signals from six depressive disorders and nine healthy subjects stimulated by positive, neutral, and negative emotional pictures and explore coupling relationship of different MEG channels. The results show that there are obvious differences on correlations between two channels of MLP32 and MRP32 with positive emotional stimulus, MLP31 and MRP31 with neutral emotional stimulus, MLP53 and MRP53 with negative emotional stimulus. In general, these channels have more correlation in patients with major depression, and can be able to distinguish depression patient from crowd. It also shows that the research of symbolic transfer entropy in MEG channel can distinguish the difference between normal and case samples, which of significance for clinical pathological estimation and diagnosis.
Muscle-Wire Glove: Pressure-Based Haptic Interface

This work follows a novel approach to information presentation through haptics using muscle-wire. The muscle-wire is extremely lightweight, silent and does not require complex circuitry. Its property to shrink in length when an electric current is applied, can have many interesting applications, some of which we present as a proof of concept of our vision. In this paper, we describe our initial prototype and a first series of user tests that demonstrates the possibility of representing discrete and continuous informations.
Seed Dormancy

This letter is not as much an expression of disagreement as an, in my view, very essential extension of Marc Cohn's opinion paper on seed dormancy research (Cohn, 1996). I will not dispute the several definitions of dormancy and germination discussed in his paper. Recent discussions on the Seed Biology Internet have clearly shown that it is virtually impossible to reach some kind of consensus that could be used in a meaningful way in seed research. Here I will mainly focus on the differences and transitions between the dormant and non-dormant states as depicted in Figure 2 of Cohn's article.
Study on the workability of Fe-Co alloy

The influence of alloy element Nb on cold workability of Fe-Co alloy was studied.It was found that the improvement in cold workability was achieved by adding trace amount of Nb to Fe-Co alloy.The heat simulation test and the soften annealing test also showed that the ductility of Fe-Co alloy with trace amount Nb is well,and the soften annealing must be conducted at a suitable temperature higher than 730℃.
Engaging African Americans in developing an intervention to reduce breast cancer recurrence: A brief report

Background To develop a culturally appropriate lifestyle intervention, involvement of its intended users is needed. Methods Members of an African American (AA) breast cancer support group participated in two 4-hour guided discussions, which were audiotaped, transcribed, and analyzed to guide the content. Results The support group collaborated with researchers to develop 24 experiential nutrition education sessions using a social cognitive framework and incorporating self-regulation skills (goal-setting, self-monitoring, problem-solving, stimulus control) and social support to enhance self-efficacy for changes in dietary intake. Conclusions Community engagement fostered autonomy, built collaboration, and enhanced the capacity of AA breast cancer survivors to participate in developing a lifestyle intervention.
Multiple Polyploidization Events across Asteraceae with Two Nested Events in the Early History Revealed by Nuclear Phylogenomics

Biodiversity results from multiple evolutionary mechanisms, including genetic variation and natural selection. Whole-genome duplications (WGDs), or polyploidizations, provide opportunities for large-scale genetic modifications. Many evolutionarily successful lineages, including angiosperms and vertebrates, are ancient polyploids, suggesting that WGDs are a driving force in evolution. However, this hypothesis is challenged by the observed lower speciation and higher extinction rates of recently formed polyploids than diploids. Asteraceae includes about 10% of angiosperm species, is thus undoubtedly one of the most successful lineages and paleopolyploidization was suggested early in this family using a small number of datasets. Here, we used genes from 64 new transcriptome datasets and others to reconstruct a robust Asteraceae phylogeny, covering 73 species from 18 tribes in six subfamilies. We estimated their divergence times and further identified multiple potential ancient WGDs within several tribes and shared by the Heliantheae alliance, core Asteraceae (Asteroideae–Mutisioideae), and also with the sister family Calyceraceae. For two of the WGD events, there were subsequent great increases in biodiversity; the older one proceeded the divergence of at least 10 subfamilies within 10 My, with great variation in morphology and physiology, whereas the other was followed by extremely high species richness in the Heliantheae alliance clade. Our results provide different evidence for several WGDs in Asteraceae and reveal distinct association among WGD events, dramatic changes in environment and species radiations, providing a possible scenario for polyploids to overcome the disadvantages of WGDs and to evolve into lineages with high biodiversity.
Reduction in periprocedural enzyme elevation by abciximab after rotational atherectomy of type B2 lesions: Results of the Rota ReoPro randomized trial.

BACKGROUND Abciximab has been shown to reduce ischemic complications and creatine kinase-myocardial band (CK-MB) elevation of both simple and complex coronary interventions. In addition to the procedural complications, one of the important mechanisms for CK-MB elevation after rotational atherectomy is an interaction between platelets and the atheromatous debris. METHODS This study was conducted to determine whether abciximab would limit the extent of periprocedural CK-MB release after rotational atherectomy of American Heart Association/American College of Cardiology type B(2) lesions in a double-blind, randomized, placebo-controlled manner. A total of 100 lesions in 100 patients were randomized with the primary end point being a CK-MB elevation of >16 U/L. RESULTS Procedural success was achieved in 100% in the abciximab arm compared with 98% in the placebo group with any CK-MB elevation >16 U/L of 8% in the abciximab versus 22% in the placebo group (P =.04). The peak creatine phosphokinase level (units per liter) was 102 +/- 14 versus 153 +/- 22 (P =.05) and the peak CK-MB level was 12.8 +/- 1.8 versus 24.6 +/- 3.5 (P =.06) between the abciximab and placebo groups, respectively. Slow-flow or postprocedure chest pain occurred in 14% in the abciximab group versus 30% in the placebo group (P =.04). There was 1 Q-wave myocardial infarction in the placebo arm and 1 nonhemorrhagic stroke in the abciximab group. CONCLUSIONS Therefore the Rota ReoPro randomized trial revealed the benefit of abciximab during rotational atherectomy in reducing procedural morbidity and CK-MB elevation, and its routine use can be justified even in moderately complex lesions undergoing rotational atherectomy.
The influence of seawater pH on U/Ca ratios in the scleractinian cold-water coral Lophelia pertusa

The increasing p CO 2 in seawater is a serious threat for marine calcifiers and alters the biogeochemistry of the ocean. Therefore, the reconstruction of past-seawater properties and their impact on marine ecosystems is an important way to investigate the underlying mechanisms and to better constrain the effects of possible changes in the future ocean. Cold-water coral (CWC) ecosystems are biodiversity hotspots. Living close to aragonite undersaturation, these corals serve as living laboratories as well as archives to reconstruct the boundary conditions of their calcification under the carbonate system of the ocean. We investigated the reef-building CWC Lophelia pertusa as a recorder of intermediate ocean seawater pH. This species-specific field calibration is based on a unique sample set of live in situ collected L. pertusa and corresponding seawater samples. These data demonstrate that uranium speciation and skeletal incorporation for azooxanthellate scleractinian CWCs is pH dependent and can be reconstructed with an uncertainty of ±0.15. Our Lophelia U / Ca–pH calibration appears to be controlled by the high pH values and thus highlighting the need for future coral and seawater sampling to refine this relationship. However, this study recommends L. pertusa as a new archive for the reconstruction of intermediate water mass pH and hence may help to constrain tipping points for ecosystem dynamics and evolutionary characteristics in a changing ocean.
Combined self-learning based single-image super-resolution and dual-tree complex wavelet transform denoising for medical images

In this paper, we propose a novel self-learning based single-image super-resolution (SR) method, which is coupled with dual-tree complex wavelet transform (DTCWT) based denoising to better recover high-resolution (HR) medical images. Unlike previous methods, this self-learning based SR approach enables us to reconstruct HR medical images from a single low-resolution (LR) image without extra training on HR image datasets in advance. The relationships between the given image and its scaled down versions are modeled using support vector regression with sparse coding and dictionary learning, without explicitly assuming reoccurrence or self-similarity across image scales. In addition, we perform DTCWT based denoising to initialize the HR images at each scale instead of simple bicubic interpolation. We evaluate our method on a variety of medical images. Both quantitative and qualitative results show that the proposed approach outperforms bicubic interpolation and state-of-the-art single-image SR methods while effectively removing noise.
Relationship Between Changes in the Temporal Dynamics of the Blood-Oxygen-Level-Dependent Signal and Hypoperfusion in Acute Ischemic Stroke

Background and Purpose— Changes in the blood-oxygen-level-dependent (BOLD) signal provide a noninvasive measure of blood flow, but a detailed comparison with established perfusion parameters in acute stroke is lacking. We investigated the relationship between BOLD signal temporal delay and dynamic susceptibility contrast magnetic resonance imaging (DSC-MRI) in stroke patients. Methods— In 30 patients with acute (<24 hours) ischemic stroke, we performed Pearson correlation and multiple linear regression between DSC-MRI parameters (time to maximum [Tmax], mean transit time, cerebral blood flow, and cerebral blood volume) and BOLD-based parameters (BOLD delay and coefficient of BOLD variation). Prediction of severe hypoperfusion (Tmax >6 seconds) was assessed using receiver–operator characteristic (ROC) analysis. Results— Correlation was highest between Tmax and BOLD delay (venous sinus reference; time shift range 7; median r=0.60; interquartile range=0.49–0.71). Coefficient of BOLD variation correlated with cerebral blood volume (median r= 0.37; interquartile range=0.24–0.51). Mean R2 for predicting BOLD delay by DSC-MRI was 0.54 (SD=0.2) and for predicting coefficient of BOLD variation was 0.37 (SD=0.17). BOLD delay (whole-brain reference, time shift range 3) had an area under the curve of 0.76 for predicting severe hypoperfusion (sensitivity=69.2%; specificity=80%), whereas BOLD delay (venous sinus reference, time shift range 3) had an area under the curve of 0.76 (sensitivity=67.3%; specificity=83.5%). Conclusions— BOLD delay is related to macrovascular delay and microvascular hypoperfusion, can identify severely hypoperfused tissue in acute stroke, and is a promising alternative to gadolinium contrast agent–based perfusion assessment in acute stroke. Clinical Trial Registration— URL: http://www.clinicaltrials. gov. Unique identifier: NCT00715533 and NCT02077582.
Mechanisms of synaptic depression at the hair cell ribbon synapse that support auditory nerve function

Significance Sensory systems use adaptation as a mechanism to enhance the range of responses to incoming stimuli. In the auditory system, the synapses between inner hair cells and dendrites of auditory nerve neurons have been pointed as the adaptation site. This synapse is responsible for converting graded acoustic signals into trains of action potentials. We present evidence showing that depletion of rapidly releasing vesicles produces an early depression of the synaptic response. Also, we observed that desensitization of postsynaptic receptors plays a fundamental role in synaptic decay. Stronger stimuli produce larger and longer lasting responses that are more profoundly affected by desensitization. Both pre- and postsynaptic mechanisms contribute to depression at this synapse, imparting multiple features to auditory nerve function. Inner hair cells (IHCs) in the cochlea are the mammalian phono-receptors, transducing sound energy into graded changes in membrane potentials, the so called “receptor potentials. ” Ribbon synapses between IHCs and auditory nerve neurons are responsible for converting receptor potentials into spike rates. The characteristics of auditory nerve responses to sound have been described extensively. For instance, persistent acoustic stimulation produces sensory adaptation, which is revealed as a reduction in neuronal spike rate with time constants in the range of milliseconds to seconds. Since the amplitude of IHC receptor potentials is invariant during this period, the classic hypothesis pointed to vesicle depletion at the IHC as responsible for auditory adaptation. In this study, we observed that fast synaptic depression occurred in responses to stimuli of varying intensities. Nevertheless, release continued after this initial depression, via synaptic vesicles with slower exocytotic kinetics. Heterogeneity in kinetic elements, therefore, favored synaptic responses with an early peak and a sustained phase. The application of cyclothiazide (CTZ) revealed that desensitization of postsynaptic receptors contributed to synaptic depression, which was more pronounced during stronger stimulation. Thus, desensitization had a twofold effect: It abbreviated signaling between IHC and the auditory nerve and also balanced differences in decay kinetics between responses to different stimulation strengths. We therefore propose that both pre- and postsynaptic mechanisms at the IHC ribbon synapse contribute to synaptic depression at the IHC ribbon synapse and spike rate adaptation in the auditory nerve.
ENAGS: energy and network-aware genetic scheduling algorithm on cloud data centers

Cloud computing plays a significant role in today's network computing by delivering virtualized resources as pay-as-you-go services over the Internet. However, the growing demand drastically increases the energy consumption of data centers, which has become a prominent problem. Hence, energy efficient solutions are required to minimize system power consumption and increase the availability of computational resources and obviously reduce the operational expenses. In this paper we present ENAGS (Energy and Network-Aware Genetic Scheduling algorithm) to minimize the energy consumption of servers and reduce the network traffic. The proposed algorithm takes into account communication dependencies among VMs and computational requirements of tasks to improve communication performance and minimize the energy consumption by maximizing the resource utilization. Our experimental results show that the proposed ENAGS algorithm can reduce data center energy consumption as well as network traffic by approximately 38% compared to other placement algorithms.
REMOVING TOXIC COMPOUNDS FROM WASTEWATER

The paper presents a hybrid method for the advanced removal of low biodegradable organic compounds from water, by combining the separation selectivity of the membrane with the oxidation efficiency of the photocatalytic process. The aim of this study is to evaluate the performance of the hybrid method to remove toxic compounds from wastewater. The advanced oxidation process, based on a photocatalytic reactor with continuous recirculation, ultraviolet (UV) radiations and a membrane, was used for the removal of 2,4–dichlorphenol (2,4-DCP). The membrane was prepared by immobilization on the carrier material such as fiberglass through the sol-gel specific method, with layer-by-layer deposition.
Tweeting #Leaders: Social media communication and retweetability of Fortune 1000 chief executive officers on Twitter

Purpose To better understand executive communication on social media, this paper examines the pattern of messages posted by chief executive officers (CEOs) on Twitter and their retweetability (rate of reposting by other users). Design/methodology/approach The study data comprises 1068 original tweets randomly selected from all Fortune 1000 CEOs tweets in 2014. The impact of the contextual factors (industry background, activeness, and Twitter age) and content factors (content types, supplementary information, and linguistic features) on retweetability was examined through regression analyses. Findings CEOs tweet to share information and insights, to promote their companies or products, to update work or life status, and to interact with the public. Original insights, promotional messages, and seasonal greetings were most likely to be retweeted. CEOs’ backgrounds, usage of hashtags, and certainty of language were also positively associated with retweetability. Practical implications CEOs may enhance their o.
Appreciative inquiry, positive deviance, and civility.

As I write this editorial, the 2016 Presidential Election remains in full swing. The unpleasantness of the rhetoric across the spectrum of voices and the profound focus on Bfixing[ have me reflecting on a trend in recent submissions to Health Care Management Review (HCMR). The trend, or hopefully just a spike, involves research reports of bullying among health care workers and cyberbullying related to the workplace. Whether this is a trend or a spike, the fact that the topic has scholarly attention may say something about our health care organizations, systems, or society at large. It feels as though scholars look for, talk about, and focus on the bad, the ugly, and the wrong. Undeniably, these exist in our health care organizations and deserve to be understood as a step toward prevention. But, as the Editor (and an individual), I_d prefer to shift the balance towardmore focus to be on what we want more of, like successes, beauty, and the correct. Making that shift requires that scholars use a different set of tools and frameworks that redirect attention from the negative toward the positive aspects and elements. Several such tools and frameworks exist, such as appreciative inquiry. The value of appreciative inquiry stems from being an approach useful for health care organizations seeking to improve by focusing on the good, the successes, and the brilliant within the health care organization (Herington et al., 2015). Creating and having exemplary role models tends to be effective in achieving broader goals. The same ought to hold true in health care organizations and discoverable through research. Reflection, use of exemplary cases, and action research can be used as part of appreciative inquiry. Another approach is to identify positive deviance, as an exemplary outlier with seemingly paradoxical success. In some instances, we may not know about these cases because we have not been looking for them, and in other cases, we looked past them. Positive deviance involves focusing on assets and involvement of the members of the organization. Identifying and studying the successes stories, using rigorous methodologies, does more than generates new knowledge about health care organizations and management of those complex systems. It also generates compassion, civility, and inspiration. These qualities are not luxuries, but essential elements of healthyhealth care organizations. I hope that some HCMR readers and authors will take up the challenge to understand how to foster these qualities in our health care providers and systems. Surely, that would be what our patients, customers, and workers would want.
The impact of FLT3 mutations on treatment response and survival in Chinese de novo AML patients

ABSTRACT Objective: Two distinct forms of FMS-like tyrosine kinase 3 (FLT3) mutations, internal tandem duplication (ITD) in the juxtamembrane domain and point mutation within the activation loop of the tyrosine kinase domain (TKD), have been identified in considerable number of patients with AML. This study was aimed to analyze the impacts of these mutations on clinical outcomes, and assess the efficacy of different therapeutic regimens (allo-HSCT, sorafenib, or conventional chemotherapy) for AML patients with FLT3 mutations after the standard induction therapy. Materials and methods: We analyzed DNA samples from 158 consecutive de novo AML patients (18–60 years, excluding APL) with FLT3 mutations between July 2010 and October 2015. Results: We found that AML patients with FLT3-TKD mutations have more favorable clinical outcomes than those with FLT3-ITD mutations. We also found that allo-HSCT therapy subgroup achieved longer OS and RFS than non-allo-HSCT therapy subgroup for FLT3-ITD positive patients (p < 0.001, p = 0.071). However, compared with the clinical outcomes in non-primary refractory patients, sorafenib did not show an obvious beneficial effect for the primary refractory patients. Further study on a large scale is still recommended. Conclusions: FLT3-TKD-mutated AML patients have more favorable clinical outcomes than those with FLT3-ITD mutations. Allo-HSCT therapy subgroup achieved longer OS and RFS than non-allo-HSCT therapy subgroup for FLT3-ITD positive patients. Compared with the clinical outcomes in non-primary refractory patients, sorafenib did not show an obvious beneficial effect for the primary refractory patients.
TV logo dataset and annotations for the convolution neural network

TV logo often implies the video content and copyright, which are important cues for video classification and retrieval. However, there are not open TV logo dataset yet. One TV logo dataset is created and Corresponding accurate annotation is provided. First, video corps of 45 kinds of TV logo is crawled, and the candidate regions covering logo and different kinds of background are extracted from the key frames, then a pixel-wise differentiated annotation method is proposed to generate a pixel by pixel annotation image. An annotation method on the generated dataset is evaluated and the experiments show that differentiated annotation helps to improve recognition accuracy.
Promoting healthy food preferences from the start: a narrative review of food preference learning from the prenatal period through early childhood

The palatable, energy‐dense foods that characterize modern environments can promote unhealthy eating habits, along with humans' predispositions to accept sweet tastes and reject those that are sour or bitter. Yet food preferences are malleable, and examining food preference learning during early life can highlight ways to promote acceptance of healthier foods. This narrative review describes research from the past 10 years focused on food preference learning from the prenatal period through early childhood (ages 2–5 years).