Miracle-dz/UniFAR-FTUs huggingface dataset:
Close Miking Empirical Practice Verification: A Source Separation Approach

Close miking represents a widely employed practice of placing a microphone very near to the sound source in order to capture more direct sound and minimize any pickup of ambient sound, including other, concurrently active sources. It is used by the audio engineering community for decades for audio recording, based on a number of empirical rules that were evolved during the recording practice itself. But can this empirical knowledge and close miking practice be systematically verified? In this work we aim to address this question based on an analytic methodology that employs techniques and metrics originating from the sound source separation evaluation field. In particular, we apply a quantitative analysis of the source separation capabilities of the close miking technique. The analysis is applied on a recording dataset obtained at multiple positions of a typical musical hall, multiple distances between the microphone and the sound source multiple microphone types and multiple level differences between the sound source and the ambient acoustic component. For all the above cases we compute the Source to Interference Ratio (SIR) metric. The results obtained clearly demonstrate an optimum close-miking performance that matches the current empirical knowledge of professional audio recording.
Instrumented nanoindentation investigation into the mechanical behavior of ceramics at moderately elevated temperatures

An analysis of indentation hardness data from three ceramic materials, zirconium diboride, silicon carbide, and titanium nitride, is presented to extract the fundamental deformation parameters at 295 to 623 K. The measured activation volume was of the order of 1 × b ^3 to 4 × b ^3 ( b is the Burgers vector). The calculated activation energies were in the range of 0.75 to 1.61 eV and are typical of lattice-controlled dislocation glide mechanism. Using finite difference simulations, it was demonstrated that there is a significant difference between the plastic strain rate and the total strain rate for materials showing substantial elastic deformation (i.e., large hardness/elastic modulus ratio). Therefore, the measured total strain rates must be converted into plastic strain rates, which require a reduction during loading and an increase during the dwell at maximum load. Additionally, importance of quantification of instrumental thermal drift was discussed and use of either short duration indentation tests or high loads was emphasized.
A Study of Recombination Mechanisms in Gallium Arsenide using Temperature-Dependent Time-Resolved Photoluminescence

Recombination mechanisms in gallium arsenide have been studied using temperaturedependent time-resolved photoluminescence-decay. New analytical methods are presented to improve the accuracy in bulk lifetime measurement, and these have been used to resolve the temperature-dependent lifetime. Fits to temperature-dependent lifetime yield measurement of the radiative-efficiency, revealing that samples grown by the Czochralski and molecular-beam-epitaxy methods are limited by radiativerecombination at 77K, with defect-mediated nonradiative-recombination becoming competitive at 300K and above. In samples grown with both doping types using molecular-beam-epitaxy, a common exponential increase in capture cross-section characterized by a high value of E∞ = (258 ± 1)meV was observed from the high-level injection lifetime over a wide temperature range (300-700K). This common signature was also observed from 500-600K in the hole-lifetime observed in n-type Czochralski GaAs where E∞ = (261 ± 7)meV was measured, which indicates that this signature parametrizes the exponential increase in hole-capture cross-section. The high E∞ value rules out all candidate defects except for EL2, by comparison with holecapture cross-section data previously measured by others using deep-level transient spectroscopy.
SOLUBILITY OF THREE LUTING CEMENTS IN DYNAMIC ARTIFICIAL SALIVA

Objective: The purpose of this study was to evaluate the solubility of three luting cements in artificial saliva. Materials and Methods: Twenty disks (10×4 mm) of polycarboxylate, zinc phosphate and glass ionomer cements were prepared according to manufactures’ instructions. After setting, they were desiccated and each ten specimens were immersed in artificial saliva with special pH (3 or 5), circulated with magnetic field for 10 days. Then disks were again desiccated and weighed. Solubility values were deduced from these different measures. Results: For the two pH, solubility were significantly lower in glass ionomer luting cement, and polycarboxylate showed the most weight loss of all the materials tested (P<0.05). The solubility values were more in acidic environment (P<0.05). Conclusion: The pH of the environment strongly affected the solubility of the materials. Cement type also has significant effects on solubility values.
CES: A System for Community Evaluation

With the development of Internet, we are gradually entering the era of big data. The size of network is increasing and the structure of network is becoming more complex. Community is a unique network structure with great research value. The task of community analysis goes through two separate phases: first, detection of meaningful community structure from a network, and second, evaluation of the appropriateness of the detected community structure. With the popularity of network research, many community detection algorithms emerged which can be grouped in categories, based on different criteria. In order to applicate community detection algorithms in real-world network analysis, we need to measure the performance of the algorithm. The performance depends on two points, that is, whether the algorithm can give the result of community division in an acceptable time, and whether the algorithm can reveal the community structure of the network with high quality. In recent years, systems used to analyze network and detect community are mushrooming. However, existing systems rarely have evaluation function, either providing social network analysis or providing data analysis service. We need a tool to evaluate community detection algorithms. In response to the challenge, the Community Evaluation System (CES) is proposed to meet the demands of community detection algorithms’ evaluation. CES can evaluate community detection algorithms with multiple metrics. It uses B/S mode, integrates Spark, Yarn and HDFS technology to support the operation of large-scale data, and experiments prove that it is effective.
Error-Robust Modes of the Retinal Population Code

Across the nervous system, certain population spiking patterns are observed far more frequently than others. A hypothesis about this structure is that these collective activity patterns function as population codewords–collective modes–carrying information distinct from that of any single cell. We investigate this phenomenon in recordings of ∼150 retinal ganglion cells, the retina’s output. We develop a novel statistical model that decomposes the population response into modes; it predicts the distribution of spiking activity in the ganglion cell population with high accuracy. We found that the modes represent localized features of the visual stimulus that are distinct from the features represented by single neurons. Modes form clusters of activity states that are readily discriminated from one another. When we repeated the same visual stimulus, we found that the same mode was robustly elicited. These results suggest that retinal ganglion cells’ collective signaling is endowed with a form of error-correcting code–a principle that may hold in brain areas beyond retina.
Twelve tips for implementation of “student-as-teacher” programs

Abstract Much has been written about the learning benefits of peer teaching for medical trainees. What remains less certain is how practically to implement “Student-as-teacher” (SaT) programs combining teacher-skills training with hands-on teaching experiences for medical students to prepare them for their roles as teachers in residency and beyond. In this article, we address this gap by outlining twelve tips for the implementation of SaT programs based on review of the literature and our experience implementing SaT curricula at our institution. We have organized the tips into three domains (i.e. preimplementation, implementation and postimplementation) to encourage SaT coordinators to iteratively consider how to continually enhance SaT programs before, during and after their implementation.
Eosinophils from eosinophilic oesophagitis patients have T cell suppressive capacity and express FOXP3

Eosinophilic esophagitis (EoE) is an antigen‐driven T cell‐mediated chronic inflammatory disease where food and environmental antigens are thought to have a role. Human eosinophils express the immunoregulatory protein galectin‐10 and have T cell suppressive capacity similar to regulatory T cells (Tregs). We hypothesized that one function of eosinophils in EoE might be to regulate the T cell‐driven inflammation in the oesophagus. This was tested by evaluating the suppressive capacity of eosinophils isolated from the blood of adult EoE patients in a mixed lymphocyte reaction. In addition, eosinophilic expression of forkhead box protein 3 (FOXP3), the canonical transcription factor of Tregs, was determined by conventional and imaging flow cytometry, quantitative polymerase chain reaction (qPCR), confocal microscopy and immunoblotting. It was found that blood eosinophils from EoE patients had T cell suppressive capacity, and that a fraction of the eosinophils expressed FOXP3. A comparison of EoE eosinophils with healthy control eosinophils indicated that the patients' eosinophils had inferior suppressive capacity. Furthermore, a higher percentage of the EoE eosinophils expressed FOXP3 protein compared with the healthy eosinophils, and they also had higher FOXP3 protein and mRNA levels. FOXP3 was found in the cytosol and nucleus of the eosinophils from both the patients and healthy individuals, contrasting with the strict nuclear localization of FOXP3 in Tregs. To conclude, these findings suggest that the immunoregulatory function of eosinophils may be impaired in EoE.
The new frontier in health services research: a behavioural paradigm guided by genetics

The incorporation of genetics into health services research has largely floundered, despite the rapidly accelerating availability of, and access to, such data. This is expected given the ethical questions involved. However, using these new resources robustly to examine population choices when it comes to health insurer selection, coverage therein and especially the subsequent use of health services is a necessary step forward, especially given the increasing prevalence of multimorbidity. Such a novel advancement in health services research may eventually propel public and private insurers to redesign their infrastructure to more accurately reflect the behavioural inclinations of their beneficiary populations. Using this resource will likely provide equally important insight for countries with extensive mixed insurer systems (like the United States) or nations with a greater emphasis on single-payer systems (such as various European models).
A ridgelet kernel regression model using genetic algorithm

In this paper, a ridgelet kernel regression model is proposed for approximation of high dimensional functions. It is based on ridgelet theory, kernel and regularization technology from which we can deduce a regularized kernel regression form. Taking the objective function solved by quadratic programming to define the fitness function, we use genetic algorithm to search for the optimal directional vector of ridgelet. The results indicate that this method can effectively deal with high dimensional data, especially those with certain kinds of spatial inhomogeneities. Some illustrative examples are included to demonstrate its superiority.
Identifying the Optimal Age to Perform Newborn Screening for Hearing Loss in Uganda

Background: Permanent congenital hearing loss affects up to 6/1000 births in developing countries. Currently, in Uganda there is no newborn screening for hearing loss (NSHL) program and no published work on this topic. Within the existing healthcare system there are two opportunities to deliver screening, at birth or 6 weeks of age when infants receive their immunizations. Aim: This study explored the outcomes of otoacoustic emission (OAE) testing in infants at birth and 6 weeks of age, to identify the optimal age for screening. Subjects and Methods: This cross-sectional pilot study recruited 60 consecutive infants from two health centres in Kampala, Uganda. Thirty infants were newborns recruited from the postnatal ward and 30 were aged 4–8 weeks from the immunization clinic, we performed OAE testing on all infants. Results: The results showed 56.7% (17/30) of newborn infants passed OAE testing compared with 90.0% (27/30) of the immunization infants, P < 0.01. Furthermore, of the 11 newborn infants aged ≥24 h of age 90.9% (10/11) passed, compared with the 19 infants <24 h of age where 37% (7/19) passed, P < 0.01. Conclusions: This study demonstrates a higher pass rate for OAE testing for infants ≥24 h of age compared to those <24 h of age. The overall lower pass rate of the newborn infants could be due to external ear debris and middle ear fluid compromising the OAE testing. These findings would support a NSHL programme in Uganda that offers screening to infants ≥24 h of age, to maximize the cost-effectiveness of the program.
Vitamin E or vitamin A protects chickens against E. coli infection.

The supplementation of either vitamin E (300 mg./kg. diet) or vitamin A (60,000 I.U./kg. diet) to a standard chick ration increased the protection of six week old immunized chickens against E coli infection, decreasing mortality from about 40% to 5%. The combination of the two vitamins, however, did not give as much protection as either vitamin alone. Vitamin E or A did not protect chicks from weight loss and severe morbidity due to infection, but slightly increased the rate of recovery.
The Role of the Task Topic in Web Search of Different Task Types

When users are looking for information on the Web, they show different behavior for different task types, e.g., for fact finding vs. information gathering tasks. For example, related work in this area has investigated how this behavior can be measured and applied to distinguish between easy and difficult tasks. In this work, we look at the searcher's behavior in the domain of journalism for four different task types, and additionally, for two different topics in each task type. Search behavior is measured with a number of session variables and correlated to subjective measures such as task difficulty, task success and the usefulness of documents. We acknowledge prior results in this area that task difficulty is correlated to user effort and that easy and difficult tasks are distinguishable by session variables. However, in this work, we emphasize the role of the task topic - in and of itself - over parameters such as the search results and read content pages, dwell times, session variables and subjective measures such as task difficulty or task success. With this knowledge researchers should give more attention to the task topic as an important influence factor for user behavior.
Association between social health insurance and choice of hospitals among internal migrants in China: a national cross-sectional study

Objectives There is a tendency to pursue higher-level hospitalisation services in China, especially for internal migrants. This study aims to investigate the choices of hospitalisation services among internal migrants, and evaluate the association between social health insurance and hospitalisation choices. Methods Data were from a 2014 nationally representative cross-sectional sample of internal migrants aged 15–59 years in China. Descriptive analyses were used to perform the distribution of healthcare facility levels for hospitalisation services, and multinomial logistic regression was applied to examine the association between social health insurance and hospitalisation choices. Results Of the 6121 inpatient care users, only 11.50% chose the primary healthcare facilities for hospitalisation services, 44.91% chose the secondary hospitals and 43.59% preferred the tertiary hospitals. The choices presented large regional variations across the country. Compared with the uninsured, social health insurance had no statistically significant effect on patient choices of healthcare facility levels among internal migrants in China, whereas socioeconomic status was positively associated with the choices. Conclusions Social health insurance had little influence on the hospital choice among the internal migrants. Thus, social health insurance should be consolidated and portable to enhance the proper incentive of health insurance on healthcare seeking behaviours.
Effects of Soundscape on the Environmental Restoration in Urban Natural Environments

Context: According to the attention restoration theory, directed attention is a limited physiological resource and is susceptible to fatigue by overuse. Natural environments are a healthy resource, which allows and promotes the restoration of individuals within it from their state of directed attention fatigue. This process is called the environmental restoration on individuals, and it is affected both positively and negatively by environmental factors. Aims: By considering the relationship among the three components of soundscape, that is, people, sound and the environment, this study aims to explore the effects of soundscape on the environmental restoration in urban natural environments. Materials and Methods: A field experiment was conducted with 70 participants (four groups) in an urban natural environment (Shenyang, China). Directed attention was first depleted with a 50-min ‘consumption’ phase, followed by a baseline measurement of attention level. Three groups then engaged in 40 min of restoration in the respective environments with similar visual surroundings but with different sounds present, after which attention levels were re-tested. The fourth group did not undergo restoration and was immediately re-tested. The difference between the two test scores, corrected for the practice effect, represents the attention restoration of individuals exposed to the respective environments. Statistical Analysis Used: An analysis of variance was performed, demonstrating that the differences between the mean values for each group were statistically significant [sig. = 0.027 (<0.050)]. Results: The results showed that the mean values (confidence interval of 95%) of each group are as follows: ‘natural sounds group’ (8.4), ‘traffic sounds group’ (2.4) and ‘machine sounds group’ (−1.8). Conclusion: It can be concluded that (1) urban natural environments, with natural sounds, have a positive effect on the restoration of an individuals’ attention and (2) the presence of different types of sounds has significantly divergent effects on the environmental restoration.
Effect of intravenous endotoxin on blood cell profiles of broilers housed in cages and floor litter environments.

Commercial broilers are constantly exposed to airborne microorganisms and endotoxin (lipopolysaccharide, LPS). It has been shown that microbial contamination of the air was higher in broiler houses using floor litter than in broiler houses using netting-type floors. The current study evaluated the effect of housing conditions on blood leukocyte profiles and tested the hypothesis that, when compared to broilers reared in clean stainless steel cages (Cage group), broilers raised on floor litter (Floor group) should experience a higher environmental challenge and have a desensitized immune system that may exhibit better tolerance/resistance to subsequent intravenous LPS challenge. Hematological parameters were evaluated prior to and following i.v. administration of 1 mg/kg BW Salmonella typhimurium LPS (dissolved at 1 mg/0.25 mL in PBS) or i.v. injection of 0.25 mL/kg BW PBS alone. The results showed that prior to LPS/PBS injection, broilers in the cage group had higher heterophil and monocyte concentrations, a higher B cell percentage within the lymphocyte population, and a higher heterophil to lymphocyte (H:L) ratio in the blood. The i.v. LPS injection resulted in 25% mortality in the cage group and 42% mortality in the floor group within 8 h post-injection. LPS reduced the concentrations of total white blood cells (WBC) and all differential WBC except eosinophils and increased thrombocyte concentrations within 1 h post-injection in both groups. All of these values returned to their respective pre-injection levels within 48 h post-injection in the surviving birds. The two groups exhibited similar overall hematological changes after LPS injection except that the cage group showed a higher H:L ratio at 8 h post-injection and a lower B-cell percentage within the lymphocyte population at 48 h post-injection when compared with the floor group. We concluded that the immune systems of broilers reared on floor litter were desensitized and exhibited less pronounced leukocyte responses to i.v. LPS when compared with those of broilers reared in clean stainless steel cages. However, such desensitization of the immune system did not help broilers survive subsequent i.v. LPS challenge.
ErbB-2 Induces Bilateral Adrenal Pheochromocytoma Formation in Mice

Pheochromocytoma (PCC) is a rare catecholamine-producing tumor that arises from the adrenal medulla and is often familial. The genetic basis for familial PCC involves mutations of RET, VHL, SHDx or NF-1 in more than 20% of cases. Additional genes may be important in pathogenesis of both familial and sporadic PCC. ErbB-2/Her2/Neu is a growth factor receptor tyrosine kinase that is frequently overexpressed in tumors and there is clinical evidence suggesting that enhanced ErbB-2 growth factor receptor signaling may play a role in PCC. In the present study, ectopic expression of an activated ErbB-2 transgene resulted in bilateral adrenal PCC. Analyses of tumor samples and normal adrenal tissue revealed that levels of the Pten tumor suppressor protein were greatly reduced in PCCs, while levels of the cell cycle regulatory protein cyclin D1 were usually increased. In addition, levels of phospo-AKT were increased in PCCs versus normal adrenal tissue. Biochemical analyses established that PCC’s were functionally active, producing abundant levels of the catecholamines, epinephrine and norepinephrine. These data establish that increased ErbB-2 growth factor receptor signaling in the adrenal medulla can lead to PCC through combined influences on Pten, AKT and cyclin
No Modes left behind: Capturing the data distribution effectively using GANs

Generative adversarial networks (GANs) while being very versatile in realistic image synthesis, still are sensitive to the input distribution. Given a set of data that has an imbalance in the distribution, the networks are susceptible to missing modes and not capturing the data distribution. While various methods have been tried to improve training of GANs, these have not addressed the challenges of covering the full data distribution. Specifically, a generator is not penalized for missing a mode. We show that these are therefore still susceptible to not capturing the full data distribution. In this paper, we propose a simple approach that combines an encoder based objective with novel loss functions for generator and discriminator that improves the solution in terms of capturing missing modes. We validate that the proposed method results in substantial improvements through its detailed analysis on toy and real datasets. The quantitative and qualitative results demonstrate that the proposed method improves the solution for the problem of missing modes and improves training of GANs.