Miracle-dz/UniFAR-FTUs huggingface dataset:
Habitual coffee consumption and blood pressure: An epidemiological perspective

This paper summarizes the current epidemiological evidence on coffee consumption in relation to blood pressure (BP) and risk of hypertension. Data from cross-sectional studies suggest an inverse linear or U-shaped association of habitual coffee use with BP in different populations. Prospective studies suggest a protective effect of high coffee intake (4 or more cups per day) against hypertension, mainly in women. Furthermore, the risk of hypertension may be lower in coffee abstainers. Randomized controlled trials, which are mostly of short duration (1–12 weeks), have shown that coffee intake around 5 cups per day causes a small elevation in BP (∼2/1 mmHg) when compared to abstinence or use of decaffeinated coffee. With regard to underlying biological mechanisms, most research has been devoted to BP-raising effects of caffeine. However, there are many other substances in coffee, such as polyphenols, soluble fibre and potassium, which could exert a beneficial effect in the cardiovascular system. Although the precise nature of the relation between coffee and BP is still unclear, most evidence suggests that regular intake of caffeinated coffee does not increase the risk of hypertension.
Recursive filters for compensating the mismatch in time-interleaved ADCs

Time-interleaved analog-to-digital converter (TIADC) mismatch compensation filters are traditionally finite impulse response (FIR) filters. The advantages of using FIR filters are that FIR filters are inherently stable and that the design techniques are readily available. In this paper, we show that, infinite impulse response (IIR) mismatch compensation filters with guaranteed stability can be designed and for the same total number of coefficients, the IIR filters achieve better mismatch compensation than their FIR counterparts. We also show that for a given spurious frequency power, our new IIR TIADC compensation filter yields more than 30% saving in the total number of multiplier coefficients when compared to the conventional FIR TIADC compensation filters.
Laryngeal preservation with induction chemotherapy for hypopharyngeal squamous cell carcinoma: 10-year results of EORTC trial 24891.

BACKGROUND We report the 10-year results of the EORTC trial 24891 comparing a larynx-preservation approach to immediate surgery in hypopharynx and lateral epilarynx squamous cell carcinoma. MATERIAL AND METHODS Two hundred and two patients were randomized to either the surgical approach (total laryngectomy with partial pharyngectomy and neck dissection, followed by irradiation) or to the chemotherapy arm up to three cycles of induction chemotherapy (cisplatin 100 mg/m(2) day 1 + 5-FU 1000 mg/m(2) day 1-5) followed for complete responders by irradiation and otherwise by conventional treatment. The end points were overall survival [OS, noninferiority: hazard ratio (preservation/surgery) ≤ 1.428, one-sided α = 0.05], progression-free survival (PFS) and survival with a functional larynx (SFL). RESULTS At a median follow-up of 10.5 years on 194 eligible patients, disease evolution was seen in 54 and 49 patients in the surgery and chemotherapy arm, respectively, and 81 and 83 patients had died. The 10-year OS rate was 13.8% in the surgery arm and 13.1% in the chemotherapy arm. The 10-year PFS rates were 8.5% and 10.8%, respectively. In the chemotherapy arm, the 10-year SFL rate was 8.7%. CONCLUSION This strategy did not compromise disease control or survival (that remained poor) and allowed more than half of the survivors to retain their larynx.
Human circular colonic smooth muscle cells possess active somatostatin receptors.

BACKGROUND & AIMS Somatostatin alters in vivo colonic motility in different species including humans. Few data are available on a cellular basis that could explain the effects of somatostatin on human colon motility. To address these issues we studied the effects of somatostatin on isolated human circular colonic smooth muscle cells to establish whether its actions are directly or neurally mediated. METHODS Circular smooth muscle cells were prepared by enzymatic digestion from surgical specimens of human colon (Sigma) and resuspended in HEPES buffer containing protease inhibitors. RESULTS Cholecystokinin (1 nM), carbachol (30 nM) and KCl (20 mM) each caused a contraction of 17%, 16.5% and 15%, respectively. 1 microM of either somatostatin-14, somatostatin-28 or SMS 201-995 alone were able to produce a contraction of 5.1%, 5.7%, and 6.8%, respectively. When smooth muscle cells were preincubated with each of the above-mentioned somatostatin analogs, cholecystokinin-mediated contraction was dose-dependently inhibited only in the presence of antiproteases. The half-maximal effective concentration (EC50) for somatostatin-14, somatostatin-28 and SMS 201-995 were similar (3.5, 5.6, 3.2 nM, respectively). CONCLUSIONS Somatostatin acts directly on human circular colonic smooth muscle cells through specific somatostatin receptors. SMS 201-995, a somatostatin receptor subtype-2 preferring analogue, shows a high affinity in inhibiting cholecystokinin-mediated contraction, suggesting the presence of somatostatin receptor subtype-2 on human circular colonic smooth muscle cells.
Unmasking the Face: A Guide to Recognizing Emotions From Facial Expressions

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Developmental regulation of the human embryonic beta-like globin gene is mediated by synergistic interactions among multiple tissue- and stage-specific elements

The stage-specific regulation of mammalian embryonic globin genes has been an experimentally elusive problem, in part because of the developmentally early timing of their expression. We have carried out a systematic analysis of truncation and internal deletion mutations within the 5'-flanking region of the human embryonic beta-like globin gene (epsilon) in erythroid and nonerythroid cell lines. Within a 670-bp region upstream from the constitutive promoter are multiple positive and negative control elements. Of these, a positive regulatory element (epsilon-PRE II) which is active only in embryonic erythroid cells is of particular interest. Remarkably, although it is inactive on its own, in the presence of other sequences located further upstream, it confers tissue- and developmental stage-specific expression on a constitutive epsilon-globin or heterologous promoter. The activity of epsilon-PRE II is also modulated by another positive regulatory domain located further downstream to direct erythroid cell-specific, but little or no embryonic stage-specific, transcription. A nuclear factor highly enriched in embryonic erythroid cells binds specifically within a 19-bp region of epsilon-PRE II. Nuclei from adult erythroid cells also contain a factor that binds to this region but forms a complex of faster electrophoretic mobility. We speculate that interactions between epsilon-PRE II and other upstream control elements play an important role in the developmental regulation of the human embryonic beta-like globin gene.
Beyond Stemming and Lemmatization: Ultra-stemming to Improve Automatic Text Summarization

In Automatic Text Summarization, preprocessing is an important phase to reduce the space of textual representation. Classically, stemming and lemmatization have been widely used for normalizing words. However, even using normalization on large texts, the curse of dimensionality can disturb the performance of summarizers. This paper describes a new method for normalization of words to further reduce the space of representation. We propose to reduce each word to its initial letters, as a form of Ultra-stemming. The results show that Ultra-stemming not only preserve the content of summaries produced by this representation, but often the performances of the systems can be dramatically improved. Summaries on trilingual corpora were evaluated automatically with Fresa. Results confirm an increase in the performance, regardless of summarizer system used.
Public awareness and attitudes towards epilepsy in Tehran, Iran

Background Epilepsy is a prototypical, stigmatised disorder. Numerous studies have been conducted regarding the public perception of epilepsy, but they are primarily from high-income western countries; few studies have taken place in low- to middle-income countries with a traditional culture and a religious orientation. Objective The public knowledge and attitudes towards epilepsy in Tehran, Iran, is studied. Design A survey of 800 subjects ranging from 18 to 85 years was randomly chosen from households in Tehran in 2009. The questionnaire used was based on the Caveness and Gallup's studies conducted in the United States in 1949 and it has been used in numerous similar studies all over the world. The mean age of the participants was 37.5 years and 46.7% were female. Pearson's Chi-squared test was used for subgroup analyses. Results The majority of subjects cited brain disorders as a cause of epilepsy, while 17% indicated the will of God as the cause. Most individuals were willing to work with a person with epilepsy, allow their children to play with a child with epilepsy, and allow people with epilepsy to use public transportation (78–82%). However, only 28% were willing to accept the marriage of a family member to someone with epilepsy. Conclusion The knowledge and attitudes towards epilepsy are similar to those in Europe, with the exception of a much lower acceptance regarding marriage to a person with epilepsy. However, the low acceptance for marrying someone with epilepsy reveals the remaining misconceptions about the nature of epilepsy in Iran, despite the high educational level in the studied population. Therefore, informational efforts must be employed to change the perception of epilepsy.
Asian Americans: Diabetes Prevalence Across U.S. and World Health Organization Weight Classifications

OBJECTIVE To compare diabetes prevalence among Asian Americans by World Health Organization and U.S. BMI classifications. RESEARCH DESIGN AND METHODS Data on Asian American adults (n = 7,414) from the National Health Interview Survey for 1997–2005 were analyzed. Diabetes prevalence was estimated across weight and ethnic group strata. RESULTS Regardless of BMI classification, Asian Indians and Filipinos had the highest prevalence of overweight (34–47 and 35–47%, respectively, compared with 20–38% in Chinese; P < 0.05). Asian Indians also had the highest ethnic-specific diabetes prevalence (ranging from 6–7% among the normal weight to 19–33% among the obese) compared with non-Hispanic whites: odds ratio (95% CI) for Asian Indians 2.0 (1.5–2.6), adjusted for age and sex, and 3.1 (2.4–4.0) with additional adjustment for BMI. CONCLUSIONS Asian Indian ethnicity, but not other Asian ethnicities, was strongly associated with diabetes. Weight classification as a marker of diabetes risk may need to accommodate differences across Asian subgroups.
Building an Interactive Multimedia Information System: The GEOMED case study

Implementation of information systems has witnessed a movement towards data types of increasing complexity. This is widely facilitated by recent advances in computing and communication. At the same time, the user community does not only need access to existing information in various systems, but efficient ways to contribute its own. This paper discusses issues on the development of an Interactive Multimedia Information System on the World-Wide Web. Reporting work on GeoMed, a new EU-funded project aiming at building a Geographical Mediation System, we indicate means of indexing, organization and management of information. Multimedia information is represented in GeoMed within electronic documents and messages, not only as passive data but as graphical user interfaces to external Information Systems. Concepts discussed include Multimedia Information Management Systems, semantics, annotation tools, knowledge representation structures and reasoning mechanisms.
Improving clustering based anomaly detection with concave hull: An application in fault diagnosis of wind turbines

Along with the rapid growth of the system complexity, the capability of self-diagnosis is desired by monitoring complex industrial systems to reduce the unplanned system downtimes. By applying data driven analysis methods such as clustering algorithms on the process data of industrial systems, the health status of systems can be deduced and the anomalous statuses can be automatically detected. The accuracy of clustering based anomaly detection using cluster centers is highly dependent on the geometry of the given data set. By a data set with unsymmetrical and concave boundary, using cluster centers as reference to measure the similarity between new observations and clusters normally leads to a high false alarm rate. This paper presented an approach to improve clustering based anomaly detection by building concave hulls for each cluster. For this purpose, a new algorithm for generating n-dimensional concave hulls is developed. The effectiveness of this approach is evaluated with real world data collected from wind turbines.
Fractional-Order $\hbox{PI}^{\lambda}\hbox{D}^{\mu}$  and Active Disturbance Rejection Control of Nonlinear Two-Mass Drive System

This study presents the application of a fractional-order <formula formulatype="inline"><tex Notation="TeX">$\hbox{PI}^{ \lambda}\hbox{D}^{\mu}$</tex></formula> and an active disturbance rejection (ADR) controller to a nonlinear two-mass system. A complete state-space mathematical model for a nonlinear two-mass system is first developed. Then, a fractional-order <formula formulatype="inline"><tex Notation="TeX">$\hbox{PI}^{\lambda}\hbox{D}^{\mu}$</tex></formula> controller and an ADR controller are both designed to regulate the speed of the system. Design procedures for both controllers are given in detail. Finally, corresponding results are compared. The extended state observer in the ADR controller is tested for torsional torque and the load machine speed with open-loop and closed-loop control structures. Performance analysis for both of the proposed controllers is confirmed by experimental results. Obtained results are also compared with the results given in the literature for the same system.
Repairing Multiple Failures with Coordinated and Adaptive Regenerating Codes

Erasure correcting codes are widely used to ensure data persistence in distributed storage systems. This paper addresses the simultaneous repair of multiple failure in such codes. We go beyond existing work (i.e., regenerating codes by Dimakis et al.) and propose coordinated regenerating codes allowing devices to coordinate during simultaneous repairs thus further reducing the costs. We define optimal coordinated regenerating codes outperforming existing codes for simultaneous repairs with respect to both storage and repair costs. We prove that deliberately delaying repairs does not bring additional gains (i.e., regenerating codes are optimal as long as each failure can be repaired before a second one occurs). Finally, we propose adaptive regenerating codes that self-adapt to the system state and prove they are optimal.
Surface Construction from Kinect RGB-D Stream

An object surface extraction from a set of point clouds extracted using a Kinect V2 sensor is presented here. First several point clouds are extracted from different angles around the object. Second point clouds are registered with each other using the Iterative Closest Point algorithm. If the angle between two camera positions is large, point clouds are manually rough aligned. Then iterative closest point algorithm provides a finer alignment. Next the object boundary is found enclosing all the points in the aligned and merged point cloud. After that a triangular mesh is created with the boundary points. Finally colors acquired from the original point cloud are applied on the triangular surface generated. For a better visual effect colors of the points are interpolated on the triangular mesh generated.
Construction of Device for Laboratory Production of Biogas

Preliminary note The aim of the paper is building of the mini digester for biogas production from energy plants. The basic structure is of welded construction from stainless steel. The mini digester consists of twelve units so that four tests simultaneously with three repetitions can be performed. Each unit consists of an eudiometer, fermenter containing the substrate and a levelling bottle for surplus closing liquid. Other components ensuring correct functioning of the mini digester are the pump and heater with thermostat, the thermometer, barometer, eudiometer clamps. Finally, some measurements with energy plants according DIN 38414 were made.
Cancer nucleus: Morphology and beyond

There are many significant morphological alterations of a nucleus of cancer cell that are detectable by light microscopy on routine staining. These changes are often associated with deranged cellular functions of cancer cell. It is difficult to understand the exact relationship between nuclear morphology and alteration of nuclear structural organization in cancer. Herein, the salient visual and subvisual morphological changes of cancer nuclei and their possible etiology and significance have been reviewed. Diagn. Cytopathol. 2010. © 2009 Wiley‐Liss, Inc.
The Relationship between Psychological Symptoms and Nicotine Dependence Level

Background and Aims: The main aim of this study is to examine whether or not nicotine dependency level differentiates in terms of psychological symptoms. Psychological symptoms can be classified under three categories: symptoms of anxiety disorders, mood disorders and psychotic disorders. Anxiety disorder includes somatization, obsessive compulsive, general anxiety and phobic symptom. Mood disorder consists of depressiveness, interpersonal sensitivity and hostility symptoms. Psychotic disorder includes paranoid thoughts and psychosis symptoms. Method: The study was conducted with 77 participants (28 female, 49 male) . “Fagerstrom Nicotine Dependence Scale” and “Brief Symptom Inventory” were used to collect data. Results: As a result of the study, it was found that nicotine dependency level differentiates in obsessive compulsive, general anxiety, psychosis, paranoid thoughts and insomnia and anorexia significantly and positively. Obsessive compulsive and general anxiety branch of anxiety disorder significantly increase the level of nicotine dependency. Depressiveness, interpersonal sensitivity and hostility symptoms branch of mood disorders differentiate with regard to the nicotine dependency level but this differentiation was not statistically significant. Paranoid thought, psychosis, anorexia and insomnia symptoms branch of psychotic disorders significantly differentiate with regard to the nicotine dependency level.
Sub-band based Log-energy and Its Dynamic Range Stretching for Robust In-car Speech Recognition

Abstract Log energy and its delta parameters, typically derived fromfull-band spectrum, are commonly used in automatic speechrecognition (ASR) systems. In this paper, we address the prob-lem of estimating log energy in the presence of backgroundnoise (usually resulting in a reduction in dynamic ranges ofspectral energies). We theoretically show that the backgroundnoise affects the trajectories of the OconventionalO log energyand its delta parameters, resulting in very poor estimation ofthe actual log energy and its delta parameters, which no longerdescribe the speech signal. We thus propose to estimate log en-ergy from the sub-band spectrum, followed by a dynamic rangestretching. Basedonspeechrecognitionexperimentsconductedon CENSREC-2 in-car database, the proposed log energy (andits corresponding delta parameters) is shown to perform verywell, resulting in an average relative improvement of 27.2%compared with the baseline front-ends. Moreover, it is alsoshown that further improvement can be achieved by incorpo-rating those new MFCCs obtained through non-linear spectralcontrast stretching.
The Role of Personal Values and Demographics in Predicting Television Viewing Behavior: Implications for Theory and Application

Abstract This study investigates the influence of values on the particular behavior of television viewing, but within the context of other variables, specifically, the demographic variables of gender, age, income, and education. Using a path analytic framework, this study supports the position that the relationship of values to behaviors needs to be investigated in the context of other relevant variables; findings of studies investigating the simple bivariate relationships of values and behavior can be misleading. In this study, the inclusion of the direct relationships between demographics and behaviors in the model reduced some effects of values on television viewing to nonsignificance, but also revealed significant values—viewing relationships that had appeared to be nonsignificant when the direct effects of demographics were excluded from the model. Discussion addresses the implications of the model for values research and the relationship of values to television viewing behavior. Implications for seg.