Miracle-dz/UniFAR-FTUs huggingface dataset:
Maladie du pool vide delta plaquettaire : à propos de 11 cas diagnostiqués au CHU de Bordeaux

La maladie du pool vide delta plaquettaire est une thrombopathie rare. Elle est definie par la presence d’un deficit quantitatif ou qualitatif en granules denses intraplaquettaires et induit des hemorragies d’intensite generalement moderee. Cette etude retrospective a ete realisee au CHU de Bordeaux chez 11 patients presentant un deficit en granules denses. L’objectif etait de mettre en perspective les caracteristiques cliniques et biologiques de ces patients largement explores afin d’ameliorer les connaissances et la prise en charge diagnostique de la maladie du pool vide delta plaquettaire. L’analyse portait sur les donnees cliniques des patients (âge, hemorragies et pathologies associees) et les resultats d’examens biologiques d’hemostase specialisee (agregation plaquettaire, etude quantitative des glycoproteines membranaires, mesure de la secretion d’ADP/ATP par luminescence, expression du CD63 apres activation, capture de mepacrine et enfin morphometrie plaquettaire et quantification des granules denses en microscopie electronique). Les resultats obtenus sont globalement concordants avec les donnees de la litterature : - les hemorragies sont generalement moderees mais peuvent parfois etre severes ; - la diversite des pathologies associees est importante, allant d’atteintes congenitales comme le syndrome de Hermansky-Pudlak a des hemopathies malignes ; - le phenotype biologique plaquettaire est tres variable d’un patient a l’autre, cependant, le deficit en granules denses est le plus souvent de type quantitatif. La maladie du pool vide delta plaquettaire est donc associee a un groupe heterogene de pathologies congenitales ou acquises et necessite des examens tres specialises pour etablir le diagnostic.
AN ESTIMATED DYNAMIC STOCHASTIC GENERAL EQUILIBRIUM MODEL OF THE EURO AREA

We thank participants in the ECB Workshop on “DSGE models and their use in monetary policy”, the San Francisco Fed/SIEPR Conference on “Macroeconomic models for monetary policy” and the NBER/EEA International Seminar on Macroeconomics (ISOM) and in particular our discussants, Harris Dellas, Stefano Siviero, Peter Ireland, Lars Svensson, Jordi Gali and Noah Williams for very useful comments. We thank Larry Christiano, Chris Sims, Fabio Canova and Frank Schorfheide for very insightful discussions. We are also grateful to Frank Schorfheide for making his code available. Finally, thanks are also due to Jim Stock (editor) and three anonymous referees of the Journal of the European Economic Association. A previous version of the paper was published at the occasion of the ISOM-conference as ECB-WP No. 171. The views expressed are solely our own and do not necessarily reflect those of the European Central Bank or the National Bank of Belgium. All remaining errors are the author’s.
Manufacturing Scheduling Using Colored Petri Nets and Reinforcement Learning

Agent-based intelligent manufacturing control systems are capable to efficiently respond and adapt to environmental changes. Manufacturing system adaptation and evolution can be addressed with learning mechanisms that increase the intelligence of agents. In this paper a manufacturing scheduling method is presented based on Timed Colored Petri Nets (CTPNs) and reinforcement learning (RL). CTPNs model the manufacturing system and implement the scheduling. In the search for an optimal solution a scheduling agent uses RL and in particular the Q-learning algorithm. A warehouse order-picking scheduling is presented as a case study to illustrate the method. The proposed scheduling method is compared to existing methods. Simulation and state space results are used to evaluate performance and identify system properties.
Neural Net Extensions of Stochastic Brand Choice Models

Flexible brand choice models which are not restricted to linear deterministic utility functions offer a way to prevent biased estimates due to nonlinear effects of predictors. One type of flexible choice models approximates deterministic utility by a multilayer perceptron. We describe several variants of this model type which differ with respect to assumptions about error terms and heterogeneity of coefficients. After dealing with appropriate estimation methods, model evaluation criteria and tools for interpreting estimation results, we give an overview of studies applying such models to brand choice data.
Probabilistic long-term prediction for autonomous vehicles

Long-term prediction of traffic participants is crucial to enable autonomous driving on public roads. The quality of the prediction directly affects the frequency of trajectory planning. With a poor estimation of the future development, more computational effort has to be put in re-planning, and a safe vehicle state at the end of the planning horizon is not guaranteed. A holistic probabilistic prediction, considering inputs, results and parameters as random variables, highly reduces the problem. A time frame of several seconds requires a probabilistic description of the scene evolution, where uncertainty or accuracy is represented by the trajectory distribution. Following this strategy, a novel evaluation method is needed, coping with the fact, that the future evolution of a scene is also uncertain. We present a method to evaluate the probabilistic prediction of real traffic scenes with varying start conditions. The proposed prediction is based on a particle filter, estimating behavior describing parameters of a microscopic traffic model. Experiments on real traffic data with random leading vehicles show the applicability in terms of convergence, enabling long-term prediction using forward propagation.
Object-Oriented Genetic Programming: An Initial Implementation

This paper describes oogp, an object-oriented genetic programming system. Oogp provides traditional genetic programming capabilities in an object-oriented framework. Among the advantages of object-oriented genetic programming are: (a) strong typing, (b) availability of existing class libraries for inclusion in generated programs, and (c) straightforward extensibility to include features such as iteration as object-oriented methods. Oogp is written in Java and makes extensive use of Java’s reflection capabilities. Oogp includes a relatively straightforward but apparently innovative simplification capability.
Stratosphere‐troposphere exchange ozone flux related to deep convection

We study the mechanisms driving stratosphere‐troposphere exchange of ozone fluxes within a chemistry‐transport model. For years 2004–2006, year‐round, most of the stratosphere‐to‐troposphere flux of O3 is associated with shear and folding around the subtropical jet, and this jet‐related flux peaks for the northern hemisphere in May. Over the northern mid‐latitude continents, however, surface convection penetrates to stratospheric levels of O3 (250 ppb), enhancing the O3 flux by 19% of the northern hemisphere total, and shifting the peak flux to June. This convection‐related O3 flux represents 49% of the total over northern mid‐latitudes in June.
Finding bugs is easy

Many techniques have been developed over the years to automatically find bugs in software. Often, these techniques rely on formal methods and sophisticated program analysis. While these techniques are valuable, they can be difficult to apply, and they aren't always effective in finding real bugs. <i>Bug patterns</i> are code idioms that are often errors. We have implemented automatic detectors for a variety of bug patterns found in Java programs. In this extended abstract<sup>1</sup>, we describe how we have used bug pattern detectors to find serious bugs in several widely used Java applications and libraries. We have found that the effort required to implement a bug pattern detector tends to be low, and that even extremely simple detectors find bugs in real applications. From our experience applying bug pattern detectors to real programs, we have drawn several interesting conclusions. First, we have found that even well tested code written by experts contains a surprising number of obvious bugs. Second, Java (and similar languages) have many language features and APIs which are prone to misuse. Finally, that simple automatic techniques can be effective at countering the impact of both ordinary mistakes and misunderstood language features.
Sovereign Default: The Role of Expectations∗

The standard model of sovereign default, as in Aguiar and Gopinath (2006) or Arellano (2008), is consistent with multiple equilibrium interest rates. Some of those equilibria resemble the ones identified by Calvo (1988) where default is likely because rates are high, and rates are high because default is likely. The model is used to simulate equilibrium movements in sovereign bond spreads that resemble sovereign ∗Preliminary and incomplete, comments are welcome: gaston.navarro@nyu.edu, juanpa@minneapolisfed.org, pteles@ucp.pt. We thank Manuel Amador, Veronica Guerrieri, Patrick Kehoe, Cristina Arellano, Fernando Alvarez and Andy Neumeyer for very useful comments. We became aware while working on this paper of Lorenzoni and Werning (2013). This is independent work there are many differences that will be highlighted but their paper precedes ours.
Methods Of Pregnancy Diagnosis In Domestic Animals: The Current Status

Methods of pregnancy diagnosis in the domestic animals can be classified into visual, clinical and laboratory methods. In most domestic animals clinical methods are currently used. Visual methods are far from perfect in domestic animals. In animals like cattle, buffaloes and mare’s recto genital palpation and trans-rectal ultrasonography continue to be the methods of choice for an accurate and early pregnancy diagnosis. In sheep, goat, sow, bitch and cat ultrasonography is the only reliable method of pregnancy diagnosis. In the camel cocking of the tail is an effective visual method of pregnancy diagnosis and recto genital and ultrasonography are also useful. Laboratory methods used in past and developed in recent years are described. The efficiency of a few of these procedures is likely to be improved in near future.
16th International Conference on Harmonisation within Atmospheric Dispersion Modelling for Regulatory Purposes

Atmospheric dispersion models are especially helpful for nuclear crisis management to anticipate the dispersion of the plume during the first hours following the release and later to analyze the transport and fate of radionuclides. In this process, the modelling of the wet deposition is a crucial point to correctly evaluate the ground contamination. The wet deposition is generally divided in two main different mechanisms, the in-cloud scavenging (rainout) and the below-cloud scavenging (washout). For both of them a large number of models are proposed in the literature reflecting the uncertainties in our understanding of these phenomena. Currently there is no scientific consensus to discriminate between these models. In order to improve our understanding on the magnitude of the modelling uncertainties a comprehensive sensitivity analysis was performed and it focused on the representation of the wet deposition fluxes. A large number of model combinations are evaluated by comparison to the available observations of ground contamination. The hierarchies of models established from different statistical indicators show the lack of robustness of the wet deposition models. The aim is to establish a list of priority parameters for the ground contamination.
Exploring the level of nature of science and its degree of revising curriculums: The case of the 7th and 2009 revised curriculums

In line with the emphasis on the importance of nature of science recently, this paper examines the degree and level at which the 2009-revised convergence science textbook, developed from the common science under the 7th curriculum in South Korea, reflected nature of science according to the development of curriculum. ‘Nature of science’ was classified according to scientific view which represents scientists' view and naive view which represents general thinking and scientific error concepts. Also, ‘Nature of science’ was classified according to the explicit method and implicit method in terms of teaching method. The level of nature of science was defined using the four occasions of scientific view, naive view, explicit teaching and implicit teaching. In order to identify the components and level of nature of science reflected in the textbook, using the 10 items which refer to Lederman(2001)'s 7 definitions, NOSAT (Nature of Science Analyzing Tool) was developed and used. The results are that, since the educational curriculum is changed from common science under 7th curriculum to 2009-revised convergence science, the degree of reflection was rather a withdrawal. On parts of theories of 7th common science curriculum except research parts, it was difficult to find explicit nature of science. Also on 2009-revised curriculum, nature of science, which is seen on 2007 curriculum, disappeared. It is suggested that the future curriculum emphasizes the importance of nature of science, and bolster the reflection of nature of science according to the changing curriculum. Nature of science should not be expressed limitedly, but instead, should be more positively reflected, and the reflection method should be not implicit but explicit, allowing direct teaching. Towards that end, writers of the textbook should have an accurate understanding of nature of science. And, for the right teaching, teachers' capabilities are important and it is necessary to train teachers to understand and act for nature of science.
Introducing Echolocation into O&M University Courses for Professionals

It is well known that echolocation makes it possible for a person who is blind to get to know their surroundings and that it strengthens an individual’s ability to move independently. In order to learn echolocation skills as a newly blind or vision impaired individual, the orientation and mobility (O&M) specialist needs to become well acquainted with these techniques. However, based on the authors’ own experiences as professionals and researcher in the field of vision rehabilitation it is anticipated that very few O&M professionals are familiar with, and practice echolocation. If people who are blind are to have the possibility of learning advanced echolocation skills, then there must be trained O&M specialists to teach echolocation. This report describes the way echolocation skills were taught at a Master’s level course in Sweden during 2011–2012.
Landslide Investigation and Correction

GENERAL IN TR O D U CTIO N We have all seen evidence of the effects of landslides in costs, incomvenience and possible safety hazards or danger to the travelling public in our travels throughout Indiana and the United States. A determined effort has been underway for a few years to correct these landslides on a priority basis as the need arises and as time is avail­ able. Landslide investigations are very time consuming to be properly and thoroughly accomplished. It takes very close cooperation between the district construction or maintenance engineer initiating the request for landslide investigation through proper channels, the soils engineer and the assigned design engineer. Certain information should accom­ pany any request for landslide investigations as follows:
Research issues in distributed operating systems

As distributed computing becomes more widespread, both in high-energy physics and in other applications, centralized operating systems will gradually give way to distributed ones. In this paper the authors discuss some current research on five issues that are central to the design of distributed operating systems: communications primitives, naming and protection, resource management, fault tolerance, and system services. For each of these issues, some principles, examples, and other considerations are given.
The Maastrichtian Stage in NW Europe, and its brachiopod zonation

The uppermost Campanian-Maastrichtian of NW Europe is divided into twelve brachiopod zones. Each zone is defined by its lower boundary in a stratotype by the appearance or disappearance of a species. The upper boundary is then formed by the lower boundary of the next succeeding zone. The zones are given binomial names using the species names of the taxa defining the lower and upper boundary respectively. The zonation is mainly based on localities in Denmark and most of the zones can be traced to Sweden, Poland, DDR, NW-Germany and eastern England. The section at Kronsmoor, NW Germany is proposed as stratotype for the lower boundary of the Maastrichtian Stage. Stevns Klint is by definition stratotype for the upper boundary and thus for the Cretaceous-Tertiary boundary. It may be substituted by Nye Kl.iv, Denmark if it can be demonstrated that it contains a hiatus at the boundary. It is formally proposed to place the boundary at the base of the Fish Clay since all available evidence points towards a global isochronous nature of the boundary clay bed.
Impact of Foreign Intellectual Property Rights Protection on U.S. Exports and FDI

Since the early 1990s, there has been a growing interest in the potential contribution of intellectual property rights (IPR) protection to global trade and investment. However, there is an ongoing debate among analysts regarding the extent to which stronger IPR actually stimulate international transactions via transfer of technology. This paper addresses this issue by evaluating how foreign intellectual property rights (IPR) protection affects how U.S. firms serve overseas markets through exports and foreign direct investment (FDI). Using panel data from 53 countries over 1994-2006, the empirical analysis was based on a dynamic system GMM modeling framework. The empirical results suggest that IPR has a weak negative effect on U.S. exports, but a statistically significant positive effect on U.S. FDI. In addition, the results also indicated that less US exports flow to countries with weak imitative ability after they strengthen IPR protection.
The effect of different nitrogen sources on mycelial growth of oyster mushroom, Pleurotus ostreatus

The production of Oyster mushroom, Pleurotus ostreatus, is sustainable, both in terms of economy and environment. Cultivation can be performed successfully on a wide range of substrates, often in the form of otherwise non-productive waste from other industries, such as agriculture and forest production. In a literary review results of studies on the fungi and its possible substrates are examined. Pleurotus is efficient in breaking down lignocellulosic wastes and its requirements on substrates for cultivation are therefore quite modest. Nonetheless many conditions can be regulated in order to optimise the mushroom production. Some general conclusions are made on what type of improvements the mushroom producer or scientist can make in terms of creating a better substrate. Experiments were made on three strains of P. ostreatus (M 2140 and M2191 from Mycelia, Belgium, and ATCC® 44309™ from ATCC, USA). The aim is to test a chemically defined medium and a variation in nitrogen sources in it with reference to radial mycelial growth and mycelial thickness. The results show growth on all media tested and the radial mycelial growth and thickness was observed to significantly differ depending on the available nitrogen source for three strains of P. ostreatus. Overall the control medium, which had a higher nitrogen content and more complex ingredients, reached the best results for both parameters. Another result is that mixtures of ammonium and the amino acid asparagine were preferred over mixtures including nitrate for all three strains. Some strain variations were observed and from this one may conclude that the requirements of the specific strains differ. This illuminates the importance of clearly presenting the strains used in future studies. Furthermore, it is suggested to either create a strain specific substrate or “train”/adapt the specific strain for a specific substrate. Further studies are needed for an improved understanding of P. ostreatus and its nutritional requirements and cultivation. In the future, additional research can improve this and the gaps in knowledge will hopefully be filled.
Revised unit-cell dimensions, space group, and chemical formula of some metallic minerals

New data are given for algodonite (formula), awaruite (formula, space group), billingsleyite (space group, unit cell), bogdanovite (formula, space group), hexatestibiopanickelite (formula), keithconnire (formula), mgriite (formula), polarite (formula), roaldite (space group), sobolevskite (space groups, unit cells), stibiopalladinite (space group, unit cell), stiitzite (formula), urvantsevite (space group, unit ce[), wairauite (space group), and weissite (space group, unit cell). The structure-tlpe AuCu, tetraauricupride, is shown to have the Pearson Symbol Code of tP2 rather than tP4, so that a(lP4) : r2a(f2). New unit-cell dimensions are given for four minerals (tetraauricupride, tetraferroplatinum, ferronickelplatinum, and tulameenite) and 19 metals in tP2 rather tharL tP4.
Notes on some Ferruginous Strata in Buckinghamshire and Wiltshire

Abstract The name Whitchurch Sands is proposed for patches of ferruginous strata scattered for 75 miles along the western edge of the Cretaceous from Stewkley, Buckinghamshire, to the Vale of Pewsey, in Wiltshire. They are interpreted as the vestiges of a marine-brackish formation of Middle Purbeck age indicating the transgressive front of an advancing sea thought to have come from the north and which left its mark farther south in the Cinder Bed of Dorset. In the past they have been regarded as Lower Greensand, Wealden, or Portland Sand. In places, e.g. Quainton, Buckinghamshire, they are overlain by undoubted Lower Greensand (Seend Ironsand) of Upper Aptian date. Both in faunal characters and in stratigraphical relations the Whitchurch Sands have much in common with the Serpulite of Hanover and the basal “Wealden” of the Bas Boulonnais.
Stakeholder Relationship Management in Online Business and Competitive Value Propositions : Evidence from the Sports

In one hand, marketers have privileges to obtain additional information about their target markets through the online businesses. On the other hand, customers and other stakeholders have an enormous flow of information to compare between competitive value propositions, available in the market. In this market competition, understanding the customers’ and other stakeholders’ value anticipations would be a central success factor for marketers to prolifically develop competitive value propositions, based on understanding the customers’ and other stakeholders’ needs, wants and expectations. Stakeholder relationship marketing has a history, as well as further potentials to understand stakeholders’ value anticipations. From this context and based on an inductive constructivist approach, this study develops insights and proposes a conceptual framework on how various sports organizations manage their stakeholder relationships through their online business platforms, in order to design and deliver competitive value propositions.