Miracle-dz/UniFAR-FTUs huggingface dataset:
Structure of the complex of a mitotic kinesin with its calcium binding regulator

Much of the transport, tension, and movement in mitosis depends on kinesins, the ATP-powered microtubule-based motors. We report the crystal structure of a kinesin complex, the mitotic kinesin KCBP bound to its principal regulator KIC. Shown to be a Ca2+ sensor, KIC works as an allosteric trap. Extensive intermolecular interactions with KIC stabilize kinesin in its ADP-bound conformation. A critical component of the kinesin motile mechanism, called the neck mimic, switches its association from kinesin to KIC, stalling the motor. KIC denies access of the motor to its track by steric interference. Two major features of this regulation, allosteric trapping and steric blocking, are likely to be general for all kinesins.
Improving Fluency in Narrative Text Generation With Grammatical Transformations and Probabilistic Parsing

In research on automatic generation of narrative text, story events are often formally represented as a causal graph. When serializing and realizing this causal graph as natural language text, simple approaches produce cumbersome sentences with repetitive syntactic structure, e.g. long chains of “because” clauses. In our research, we show that the ﬂuency of narrative text generated from causal graphs can be improved by applying rule-based grammatical transformations to generate many sentence variations with equivalent semantics, then selecting the variation that has the highest probability using a probabilistic syntactic parser. We evaluate our approach by generating narrative text from causal graphs that encode 100 brief stories involving the same three characters, based on a classic ﬁlm of experimental social psychology. Crowdsourced workers judged the writing quality of texts generated with ranked transformations as significantly higher than those without, and not sig-niﬁcantly lower than human-authored narratives of the same situations.
in Computer Science

This paper presents an inconsistency tolerant semantics for the Description Logic ALC called Preferential ALC ( p-ALC ). A p-ALC knowledge base is comprised of defeasible and non-defeasible axioms. The defeasible ABox and TBox are labelled with conﬁdence weights that could reﬂect an axiom’s provenance. Entailment is deﬁned through the notion of preferred interpretations which minimise the total weight of the inconsistent axioms. We introduce a modiﬁed ALC tableau algorithm in which the open branches give rise to the preferred interpretations, and show that it can compute p-ALC entailment by refutation. The modiﬁed algorithm is implemented as an incremental answer set program (ASP) that exploits optimisation to capture preferred interpretations of p-ALC .
Integrating a Bayesian net solver with the KBCW Comlink System and a network intrusion diagnosis system

This thesis attempts to demonstrate the practical aspect of applying probabilistic methods, namely Bayesian nets, towards solving a variety of applications. Uncertainty comes into play when dealing with real world applications. Rather than trying to solve these problems exactly, a probabilistic approach is more feasible and can provide useful results. For this project, a Bayes net solver was integrated with a network intrusion detector with resource stealing the primary attack that was focused upon. A Bayes net solver was also integrated into the Knowledge Based Collaboration Webs (KBCW) Comlink system. The results show that such an integration between different ideas can be both useful and productive, providing functionality that neither alone could accomplish. The project is a successful demonstration of the potential benefits that Bayesian nets can provide. Thesis Supervisor: Howard E. Shrobe Title: Professor
Running head : The Role of Power in Conflict The Role of Power in Conflict in Adult Close Relationships by

Past research has shown that conflict occurs regularly in close relationships and has significant implications for relationship wellbeing. The purpose of this study was to investigate the role of perceived power in conflict resolution in romantic relationships. The study examined the power, relationship satisfaction, and conflict behaviors of 37 dating couples. Participants provided ratings of power and relationship satisfaction, and then participated in a 6-minute videotaped conflict discussion, which was systematically observed and coded for both positive and negative conflict behaviors. Results indicated that individuals with high perceived power demonstrated less positive and more negative affect during conflict. Furthermore, results demonstrated that perceived power equality versus inequality is associated with a number of behavioral tendencies during conflict, and gender is a significant moderator of these associations. Implications and directions for future research are discussed.
Sensory System for Implementing a Human—Computer Interface Based on Electrooculography

This paper describes a sensory system for implementing a human–computer interface based on electrooculography. An acquisition system captures electrooculograms and transmits them via the ZigBee protocol. The data acquired are analysed in real time using a microcontroller-based platform running the Linux operating system. The continuous wavelet transform and neural network are used to process and analyse the signals to obtain highly reliable results in real time. To enhance system usability, the graphical interface is projected onto special eyewear, which is also used to position the signal-capturing electrodes.
An instrument for the assessment of diarrhoeal severity based on a longitudinal community-based study

Objective Diarrhoea is a significant contributer to morbidity and is among the leading causes of death of children living in poverty. As such, the incidence, duration and severity of diarrhoeal episodes in the household are often key variables of interest in a variety of community-based studies. However, there currently exists no means of defining diarrhoeal severity that are (A) specifically designed and adapted for community-based studies, (B) associated with poorer child outcomes and (C) agreed on by the majority of researchers. Clinical severity scores do exist and are used in healthcare settings, but these tend to focus on relatively moderate-to-severe dehydrating and dysenteric disease, require trained observation of the child and, given the variability of access and utilisation of healthcare, fail to sufficiently describe the spectrum of disease in the community setting. Design Longitudinal cohort study. Setting Santa Clara de Nanay, a rural community in the Northern Peruvian Amazon. Participants 442 infants and children 0–72 months of age. Main outcome measures Change in weight over 1-month intervals and change in length/height over 9-month intervals. Results Diarrhoeal episodes with symptoms of fever, anorexia, vomiting, greater number of liquid stools per day and greater number of total stools per day were associated with poorer weight gain compared with episodes without these symptoms. An instrument to measure the severity was constructed based on the duration of these symptoms over the course of a diarrhoeal episode. Conclusions In order to address limitations of existing diarrhoeal severity scores in the context of community-based studies, we propose an instrument comprised of diarrhoea-associated symptoms easily measured by community health workers and based on the association of these symptoms with poorer child growth. This instrument can be used to test the impact of interventions on the burden of diarrhoeal disease.
An Updated Phylogeny of the Human Y-Chromosome Lineage O2a-M95 with Novel SNPs

Though the Y-chromosome O2a-M95 lineage is one of the major haplogroups present in eastern Asian populations, especially among Austro-Asiatic speaking populations from Southwestern China and mainland Southeast Asia, to date its phylogeny lacks structure due to only one downstream SNP marker (M88) assigned to the lineage. A recent array-capture-based Y chromosome sequencing of Asian samples has yielded a variety of novel SNPs purportedly belonging to the O2a-M95 lineage, but their phylogenetic positions have yet to be determined. In this study, we sampled 646 unrelated males from 22 Austro-Asiatic speaking populations from Cambodia, Thailand and Southwestern China, and genotyped 12 SNP makers among the sampled populations, including 10 of the newly reported markers. Among the 646 males, 343 belonged to the O2a-M95 lineage, confirming the supposed dominance of this Y chromosome lineage in Austro-Asiatic speaking populations. We further characterized the phylogeny of O2a-M95 by defining 5 sub-branches: O2a1*-M95, O2a1a-F789, O2a1b*-F1252, O2a1b1*-M88 and O2a1b1a -F761. This updated phylogeny not only improves the resolution of this lineage, but also allows for greater tracing of the prehistory of human populations in eastern Asia and the Pacific, which may yield novel insights into the patterns of language diversification and population movement in these regions.
The research on user satisfaction of easy teaching Web of Taipei assessed via information quality, system quality, and Technology Acceptance Model

In the digital era, using information technology to search valuable information is one of the important skills. Taipei City Government set up Easy Teaching Web of Taipei, integrates scattered knowledge in the field of education and human resources, and build a knowledge-sharing platform for teachers. However, it is still important to understand how to improve the usage of Easy Teaching Web of Taipei to teachers. This research applied the Technology Acceptance Model as research foundation, and the Information Systems Success Model was also considered as impact factor in this research, to understand the teachers to the satisfaction of the digital platform. There are 318 valid samples by random selected from members to fill out a developed pencil-paper questionnaire. The multiple-regression was used for data analysis, the empirical results lead to four conclusions. First, Information Quality (IQ) can predict Perceived Usefulness (PU) and Perceived Ease of Use (PEOU). Second, System Quality (SQ) can predict PU and PEOU. Third, PEOU can predict PU and Attitude toward using (ATU). Fourth, ATU can predict User Satisfaction (US). According to research finding that Easy Teaching Web can promote the user satisfaction by improve easy use of the system.
BI OM A 20 06 P roo fs ENTROPY-DRIVEN EXPLORATION AND EXPLOITATION IN EVOLUTIONARY ALGORITHMS

Every evolutionary algorithm needs to address two important facets: exp loration and exploitation of a search space. Evolutionary search must combine e xploration of the new regions of the space with exploitation of the potential solutions alrea dy identified. The necessity of balancing exploration with exploitation needs to be intelligent. This paper introduces an entropy-driven exploration and exp loitation approach for evolutionary algorithms. Entropy represents the amount of disorder of the population, where an increase in entropy represents an increase in div rsity. New kinds of entropy to express diversity and to control the entropy -driven approach are discussed.
Architectural Run-time Models for Performance and Privacy Analysis in Dynamic Cloud Applications

Building software systems by composing third-party cloud services promises many benefits such as flexibility and scalability. Yet at the same time, it leads to major challenges like limited control of third party infrastructures and runtime changes which mostly cannot be foreseen during development. While previous research focused on automated adaptation, increased complexity and heterogeneity of cloud services as well as their limited observability, makes evident that we need to allow operators (humans) to engage in the adaptation process. Models are useful for involving humans and conducting analysis, e.g. for performance and privacy. During operation the systems often drifts away from its design-time models. Run-time models are kept insync with the underlying system. However, typical run-time models are close to an implementation level of abstraction which impedes understandability for humans. In this vision paper, we present the iObserve approach to target aforementioned challenges while considering operationlevel adaptation and development-level evolution as two mutual interwoven processes. Central to this perception is an architectural run-time model that is usable for automatized adaptation and is simultaneously comprehensible for humans during evolution. The run-time model builds upon a technology-independent monitoring approach. A correspondence model maintains the semantic relationships between monitoring outcomes and architecture models. As an umbrella a megamodel integrates design-time models, code generation, monitoring, and run-time model update. Currently, iObserve covers the monitoring and analysis phases of the MAPE control loop. We come up with a roadmap to include planning and execution activities in iObserve.
A 45-dB, 150-Hz, and 18-mW Touch Controller for On-Cell Capacitive TSP Systems

A touch controller is proposed for on-cell capacitive touch screen panel systems, which adopts a newly proposed peaking noise detector and low-frequency rejection filters. Implemented in a 0.35-μmCMOS, the proposed touch controller with 3.3-V drive signal shows the maximum signal-to-noise ratio and scan rate of 45 dB and 150 Hz, respectively, while consuming 18 mW from a 3.3-V supply.
An LP 7 / 4-approximation for the Tree Augmentation Problem

In the Tree Augmentation Problem (TAP) the goal is to augment a tree T by a minimum size edge set F from a given edge set E such that T ∪ F is 2-edge-connected. The best known approximation ratio for the problem is 1.5 [5, 12]. Several paper analysed integrality gaps of LP and SDP relaxations for the problem. In [13] is given a simple LP with gap 1.5 for the case when every edge in E connects two leaves of T . Recently, Cheriyan and Gao [1] showed that a certain SDP relaxation obtained by the Lasserre lift-and-project method has integrality gap 7/4 + ǫ. Here we show, by a simple and short proof, that a modification of the LP used in [13] has integrality gap 7/4, which is achieved by the combinatorial algorithm of [12].
CHARACTERISTICS OF SELF-DETERMINATION OF STUDENTS WITH DISABILITIES

The article describes the psychological characteristics of students with disabilities. Their individual psychological characteristics are identified and they indicate the existence of effective models of interactions with their social environment, adequate self-acceptance, enough active life philosophy in such students. The article determines that such personality formations as life goals, personal autonomy, desire for personal growth, self-confidence are the most important for the development of self-determination of students with disabilities.
Towards a Real-time Gaze-based Shared Attention for a Virtual Agent

This paper investigates work towards a real-time user interface for testing shared-attention behaviours with an embodied conversational agent. In two-party conversations, shared attention, and related aspects such as interest and engagement, are critical factors in gaining feedback from the other party and allowing an awareness of the general state of the interaction. Taking input from a single standard webcamera, our preliminary system is capable of processing the users eye and head directions in real-time. We are using this detection capability to inform the interaction behaviours of the agent and enable it to engage in simple shared attention behaviours with the user and objects within the scene in order to study in more depth some critical factors underpinning engagement.
ANALISIS CYBERBULLYING DI MEDIA SOSIAL TWITTER(Studi Pada Akun Twitter@ahmaddhaniprast Periode BulanFebruari-Juni 2016)

Cyberbullying merupakan tindakan penghinaan, kekerasan psikis, atau intimidasi yang dilakukan seseorang, kelompok, atau institusi melalui perangkat teknologi dan informasi di media siber terhadap orang, kelompok, atau institusi lain. Tujuan penelitian ini adalah untuk mengetahui dan menganalisis isi teks cuitan cyberbullying pengguna twitter terhadap akun twitter @ahmaddhaniprast. Metode penelitian yang digunakan adalah menggunakan metode analisis wacana Van Djik. Teori Hyperpersonal Model digunakan sebagai teori analisis penelitian. Hasil dari penelitian ini adalah cyberbullying yang dilakukan oleh para followers disebabkan cuitan-cuitan Ahmad Dhani yang dianggap kasar dan kontrovesial. Selain itu faktor kebencian atau ketidaksukaan terhadap sosok Ahmad Dhani yang dikarenakan citra negatif dirinya juga merupakan alasan lain mengapa followers melakukan cyberbullying terhadap Ahmad Dhani. Jenis cyberbullying yang dilakukan pengguna twitter terhadap akun twitter @ahmaddhaniprast terdiri dari flaming, dinegration, dan masquerade. Ditinjau berdasarkan karakteristik cyberbullying, Ahmad Dhani mendapatkan cyberbullying dengan karakteristik agresif. Selain itu logika desain pesan pengguna twitter yang melakukan cyberbullying mereka mengemas pesan dengan tipe logika pesan ekspresif. Kata Kunci : Analisis Wacana, Cyberbullying, Teori Hyperpersonal Model, Teun van Dijk, Twitter ABSTRACT Cyberbullying constituting the action of contempt, psychological abuse, or intimidation which a person does, group, or institution through the technology and information in the cyberspace against the group or other institutions. The purpose of this research was to find and analyze tweets containing cyberbullying of the users of Twitter to Twitter account @ahmaddhaniprast. The research used discourse analysis by Teun van Dijk and hyperpersonal model to analyze the texts. The results show that cyberbullying conducted by the followers caused by Ahmad Dhani tweets that considered inappropriate and controversial. In addition, hatred or dislike were other reasons why they do the cyberbullying to Ahmad Dhani. Kinds of cyberbullying against twitter account @ahmaddhaniprast found in the research were flaming, dinegration, and masquerade. In terms of the characteristic, cyberbullying to Ahmad Dhani can be categorized as aggressive. While regarding design logic of the messages, it can be categorized as expressive. Keywords : Cyberbullying, Discourse Analysis,
Secondary school pupils' experiences of managed moves : an interpretative phenomenological analysis

Managed moves were conceived of as a means of giving a pupil a ‘fresh start’ in another school, often when the pupil is deemed to be at risk of permanent exclusion. Little research on managed moves has been published to date in spite of their prevalence in English and Welsh schools over the past decade. Existing research has largely focused on the views of professionals involved and there has been no published research focusing solely on the perspectives of the pupils who have had managed moves. The aim of this study was to add to the body of psychological research on managed moves through an exploration of pupil experience. Semi-structured interviews were carried out with six Year 10 and 11 pupils who had recently undergone a managed move between mainstream comprehensive schools. Interview transcripts were analysed using interpretative phenomenological analysis (IPA). From the interview data, themes for each participant emerged. These led to the identification of four overarching themes occurring across the participant group: the self as vulnerable; the impact of support on the self; identity as a learner; and the need to belong. The findings were discussed in the context of existing literature. Implications for practice for educational psychology services and local authorities were considered, particularly to consider how schools can be supported in understanding factors that may impact on pupils experiencing managed moves and helped to support pupils throughout the process.
Endothelial Growth Factor Expression and Angiogenesis by Modulating Heparin Binding Receptors Differentially Regulate Angiopoietin-2 and Vascular 2 and AT 1 Angiotensin

Angiotensin II (Ang II)–mediated signals are transmitted via heparin binding epidermal growth factor (EGF)–like growth factor (HB-EGF) release followed by transactivation of EGF receptor (EGFR). Although Ang II and HB-EGF induce angiogenesis, their link to the angiopoietin (Ang)–Tie2 system remains undefined. We tested the effects of Ang II on Ang1, Ang2, or Tie2 expression in cardiac microvascular endothelial cells expressing the Ang II receptors AT1 and AT2. Ang II significantly induced Ang2 mRNA accumulations without affecting Ang1 or Tie2 expression, which was inhibited by protein kinase C inhibitors and by intracellular Ca 21 chelating agents. Ang II transactivated EGFR via AT1, and inhibition of EGFR abolished the induction of Ang2. Ang II caused processing of pro–HB-EGF in a metalloproteinase-dependent manner to stimulate maturation and release of HB-EGF. Neutralizing anti–HB-EGF antibody blocked EGFR phosphorylation by Ang II. Ang II also upregulated vascular endothelial growth factor (VEGF) expression in an HB-EGF/EGFR–dependent manner. AT 2 inhibited AT1-mediated Ang2 expression and phosphorylation of EGFR. In an in vivo corneal assay, AT 1 induced angiogenesis in an HB-EGF–dependent manner and enhanced the angiogenic activity of VEGF. Although neither Ang2 nor Ang1 alone induced angiogenesis, soluble Tie2-Fc that binds to angiopoietins attenuated AT 1-mediated angiogenesis. These findings suggested that (1) Ang II induces Ang2 and VEGF expression without affecting Ang1 or Tie2 and (2) AT 1 stimulates processing of pro–HB-EGF by metalloproteinases, and the released HB-EGF transactivates EGFR to induce angiogenesis via the combined effect of Ang2 and VEGF, whereas AT 2 attenuates them by blocking EGFR phosphorylation. Thus, Ang II is involved in the VEGF-Ang-Tie2 system via HB-EGF–mediated EGFR transactivation, and this link should be considerable in pathological conditions in which collateral blood flow is required. (Circ Res. 2001;88:22-29.)
"Shadow security" as a tool for the learning organization

Traditionally, organizations manage information security through policies and mechanisms that employees are expected to comply with. Non-compliance with security is regarded as undesirable, and often sanctions are threatened to deter it. But in a recent study, we identified a third category of employee security behavior: shadow security. This consists of workarounds employees devise to ensure primary business goals are achieved; they also devise their own security measures to counter the risks they understand. Whilst not compliant with official policy, and sometimes not as secure as employees think, shadow security practices reflect the working compromise staff find between security and "getting the job done". We add to this insight in this paper by discussing findings from a new interview study in a different organization. We identified additional shadow security practices, and show how they can be transformed into effective and productivity-enabling security solutions, within the framework of a learning organization.