Miracle-dz/UniFAR-FTUs huggingface dataset:
Building a virtual system of systems using docker swarm in multiple clouds

The software industry has been embracing the multi-cloud infrastructure for the design and adaptation of complex and distributed software systems. This new hybrid cloud infrastructure makes it possible to mix and match platforms and cloud providers for various software development activities. There are several benefits of the multi-cloud infrastructure such as lower level of vendor lock-in and minimize the risk of widespread data loss or downtime. However, it has many challenges such as non-standard and inherent complexity due to different technologies, interfaces, and services. Docker has introduced container-based software development approach in the past few years and gaining popularity in the software industry. It has recently introduced its distributed system development tool called Swarm, which extends the Docker container-based software development process on multiple hosts in multiple clouds without any interoperability issue. Docker Swarm-based distributed software development is a newborn approach for the cloud industry; nonetheless, it has a huge potential to provide multi-cloud development environment without worrying the complexity of it. This paper presents the simulation of building a virtual system of systems (SoS) for the distributed software development process on multiple clouds. This simulation of virtual SoS is based on Docker Swarm, VirtualBox, Mac OS X, nginx and redis. However, the same SoS can be created on any of the Docker supported cloud by just changing the driver name to the desired cloud name such as Amazon Web Services, Microsoft Azure, Digital Ocean, Google Compute Engine, Exoscale, Generic, OpenStack, Rackspace, IBM Softlayer, VMware vCloud Air.
Polycystic Kidney Disease Evaluation by Magnetic Resonance Imaging in Ischemia-Reperfusion Injured PKD1 Knockout Mouse Model: Comparison of T2-Weighted FSE and True-FISP

Objective:To investigate the efficacy of true fast imaging with steady state precession (true-FISP) compared with T2-weighted fast spin echo (T2W-FSE) in monitoring changes in cyst volume and renal expansion in an ischemia reperfusion (IR) injured PKD1 knockout (IKO) mouse model. Materials and Methods:The animal study was approved by the local institutional authority. A total of 24 mice (14 PKD1 IKO mice and 10 control mice) were sequentially scanned on a 4.7-T scanner from 4 to 12 weeks after IR injury and the cysts and kidney volumes were measured from true-FISP and T2W-FSE MR images. Signal-to-noise ratio (SNR) and contrast-to-noise ratio (CNR) were calculated for the images generated from both methods. Results:Cyst SNR and CNR in true-FISP images were significantly higher than in images employing the T2W-FSE sequence (P < 0.05). Both methods demonstrated kidney volume increase as well as cyst growth after IR injury in the mouse model. The kidney and cysts volume at different time points were strongly correlated between true-FISP and T2W-FSE measurements (rkidney = 0.99, rcysts = 0.97). Conclusion:The true-FISP method offers shorter scan times and higher cyst SNR and cyst to kidney tissue contrast than T2W-FSE. Both sequences have identical accuracy in measuring the cysts and kidney volume changes in mice with PKD.
Effects of Fuzheng Huayu 319 recipe on liver fibrosis in chronic hepatitis B.

AIM:To investigate clinic effects of Fuzheng Huayu 319 recipe (319 recipe) on liver fibrosis in chronic hepatitis B.METHODS:Ninety-five patients with chronic hepatitis B were divide into the treated (63 cases) and control (32 cases) group, and orally administrated with 0.5g 319 capsule or 0.5g Dahuang Zhachong pill tid for 3 months, respectively. The liver functions and serological fibrotic markers were observed before and after treatment, 12 cases in the treated group were examined with liver biopsy.RESULTS:Three hundreds nineteen recipe could remarkably decreased serum ALT level and total bilirubin and significantly improve serum albumin and A/G ratio. Its effects were better than Dahuang Zhachong pill. Before treatment, patients'serum monamine oxidase activities, tissue inhibitor of metalloproteinase (TIMP)-1, procollagen type and laminin were all higher than those of health peoples. These levels decreased remarkably after treatment,and urine hydroxyproline level increased significantly (P < 0.001-0.05). Compared with the control, the improvement in treated group was better than that in the control except TIMP-1. According to the scoring system for staging of chronic hepatitis, the fibrotic extents of 7 cases among 12 cases examined by liver biopsy decreased remarkably (1 case decreased by 3 scores, 5 by 2 scores, 1 by 1 score). CONCLUSION:Fuzheng Huayu 319 recipe had good therapeutic effects on chronic hepatitis B, it could reverse the development of liver fibross to some extent. In general its effects were better than that of Dahuang Zhachong pill.
Effects of Storage on Venous and Capillary Blood Samples: The Influence of Deferoxamine and Butylated Hydroxytoluene on the Fatty Acid. Alterations in Red Blood Cell Phospholipids

Fatty acid concentrations in plasma and red blood cell phospholipids isolated from paired venous and capillary blood samples were compared and the effect of storage at -20 degrees C was evaluated as well. Plasma fatty acid profiles from venous and capillary blood were found to be comparable and not affected by up to four weeks of storage, while fatty acid profiles of venous and capillary red blood cells were no longer comparable after four weeks. Substantial losses of long-chain polyunsaturated fatty acids were observed in capillary red blood cells. To investigate whether the observed long-chain polyunsaturated fatty acids loss could be prevented, capillary red blood samples were stored for up to one year at -50 degrees C in the presence of the iron-binding agent deferoxamine or the free radical scavenger butylated hydroxytoluene. Both compounds protected the long-chain polyunsaturated fatty acids. Similarly, storage of red blood cell lipid extracts at -50 degrees C for up to one year was not associated with reduced levels of long-chain polyunsaturated fatty acids. In conclusion, the lipid loss from capillary red blood cells can be reduced for at least one year during storage at -50 degrees C with prior addition of either a metal chelating compound or a free radical scavenger, or by preparing lipid extracts of the samples within one week of blood collection.
Measuring destination image an approach by an attribute‐based analysis

Product image formation process is a valuable insight for correct understanding of consumer behaviour. When product is a tourism destination, image formation is even more important due to the inability of pretest the tourist product. This framework gives place to the present research on tourism destination image. The paper starts with a litterature review on the meaning and measurement of destination image divided into two main approaches: the conceptual and the methodological. Secondly, the results of an empirical investigation are reported: it deals with the assessment of attribute‐based destination image of sun and beach resorts on the Spanish Mediterranean coast. The aim and contribution of the paper are to provide an example of one methodological procedure for measurement of destination image (the Principal Component Analysis) which allows, in a first step, to obtain a structure of perceptions on sun and beach destinations. A description of the images of the resorts investigated is also reported in order to understand better perceptions on the tourism market.
Molecular Mechanism of Basic Calcium Phosphate Crystal-induced Activation of Human Fibroblasts

Synovial fluid basic calcium phosphate (BCP) crystals are markers of severe joint degeneration in osteoarthritis. BCP crystals cause mitogenesis of articular cells and stimulate matrix metalloprotease production, thus promoting degradation of articular tissues. Previous work suggested that BCP crystal-induced cell activation required intracellular crystal dissolution, induction of proto-oncogene expression, and activation of signal transduction pathways involving protein kinase C and mitogen-activated protein kinases. Here we further elucidate the mechanisms of BCP crystal-induced cell activation as BCP crystals activate transcription factors nuclear factor κB and activator protein 1 in human fibroblasts. We confirm the role of protein kinase C in BCP crystal-induced mitogenesis in human fibroblasts. In contrast, we demonstrate that BCP crystals do not activate signal transduction pathways involving protein tyrosine kinases or phosphatidylinositol 3-kinase. These data further define the mechanism of cell activation by BCP crystals and confirm its selectivity, an observation that may have therapeutic implications.
Is lean manufacture universally relevant? An investigative methodology

Observes that although the concept of lean manufacture is well understood, little work has been carried out to determine its applicability to high‐value, low‐volume complex products. Proposes a methodology for enabling an examination of the degree of relevance of lean manufacturing to such products, using a model of a typical lean high‐volume automotive producer as a base, comparing the drivers faced, the practices adopted to respond and the type of measures used to assess effectiveness. Provides an explanation as to how this approach was applied to the civil aerospace industry as an example of those products the authors have chosen to define as “super value goods”, together with some initial first line results.
Rapid and specific isolation of radioactive glucose from biological samples.

An easy, reliable, and specific ion-exchange method is presented for isolating glucose for specific radioactivity determinations from both blood plasma and buffered in vitro incubation media. The use of a glucose binding resin (borate-charged anion resin) combined speed of ion exchange with specificity of derivative formation. Glucose specific radioactivities, determined by ion exchange on protein-free filtrates of plasma containing [carbon-14] glucose, show excellent agreement with those from the popular glucose pentaacetate derivative method and are less variable. Carry-over of labeled acetate, propionate, lactate, glyoxylate, alanine, aspartate, or glutamate into the glucose fraction is less than . 2%. Glycerol carryover is 1.2%. Glucose recovery is increased about three times that of the glucose pentaacetate derivative method and averaged 94% from plasma filtrates.
Propranolol Premedication Blunts Stress Response to Nitroprusside Hypotension

Hypotension was induced in sixteen patients with nitroprusside during anesthesia for surgical correction of cerebral aneurysms. Eight patients were premedicated with propranolol (180 mg orally) for one day and the other eight were not. Before the start of anesthesia, the untreated patients had a mean arterial pressure of 102 ± 3 mm Hg, a heart rate of 76 ± 2 beats/min, and plasma epinephrine and norepinephrine concentrations of 114 ± 21 and 258 ± 34 pg/ml, respectively. The propranolol-premedicated patients came to the operating room in a significantly different clinical state with a mean arterial pressure of 92 ± 3 mm Hg, a heart rate of 71 ± 2 beats/min, and plasma epinephrine and norepinephrine concentrations of 76 ± 28 and 144 ± 28 pg/ml. During induced hypotension, plasma epinephrine and norepinephrine concentrations increased significiantly in both groups (454 ± 42 and 730 ± 58 pg/ml in the untreated patients, 160 ± 48 and 419 ± 67 pg/ml in the propranolol premeditated patients), but the increase in catecholamines was significantly greater in the untreated patients. Thirty minutes after nitroprusside was discontinued, epinephrine and norepinephrine concentrations were higher than in the awake state in untreated patients and were associated with rebound hypertension and tachycardia. In contrast, in propranolol-premedicated patients, plasma epinephrine and norepinephrine concentrations decreased towards the preanesthesia values, mean arterial pressure gradually returned to the prehypotension level, and heart rate remained unchanged. This study thus demonstrates that propranolol premedication attenuates the release of catecholamines in response to nitroprusside-induced hypotension.
OPTIMAL BUS SUBSIDY AND CROSS SUBSIDY WITH A LOGIT CHOICE MODEL

This paper investigates the impact on bus subsidy analysis of using a probabilistic (logit) choice model predicting random and planned user behaviour. The paper addresses the question of the conventional negative relationships between optimal unit subsidy and route patronage. The paper shows that this result continues to hold under a logit model. There can also be rapid increases in total subsidy for small increases in patronage. (A)
Reduced Rates of Skeletal Remodeling Are Associated with Increased Bone Mineral Density During the Development of Peak Skeletal Mass

Two related studies were conducted to assess the associations between markers of skeletal modeling and remodeling in healthy children. Members of monozygotic twin pairs, aged 6–14, enrolled in a clinical trial of calcium supplementation, were studied at the end of the period of supplementation and for 3 years thereafter. Supplemented children had significantly higher rates of gain in bone mineral density (BMD) (+3% on average) during the period of supplementation accompanied by significantly lower concentrations of serum osteocalcin (OC, −15%). During postsupplement follow‐up, both differences in BMD and OC disappeared. Black females, age matched to the baseline ages of the white children, had significantly lower serum concentrations of both OC and tartrate‐resistant acid phosphatase (TRAP) at all ages and higher BMDs. When stratified on serum TRAP concentrations, regardless of race, children with lower concentrations had significantly higher BMDs, and no racial differences were apparent. In regression models accounting for 70–80% of the variability in BMD in children, body size and TRAP, but not race, remained significantly associated with BMD. The skeletal advantages seen with calcium supplementation and black race appear to be associated with reduced rates of skeletal turnover. Given that markers of turnover during growth reflect both skeletal modeling and remodeling, and there is no apparent advantage to reduced skeletal modeling, it seems probable that reduced remodeling is the factor that accounts for the increases in bone mass.
Reforming Equal Pay Laws

Despite 33 years of equal pay legislation, the gender pay gap remains stubbornly high. Multiple equal pay claims in the public sector have forcefully exposed the weaknesses, both of the Equal Pay Act and of the complaints-led model of enforcement on which it is based. This article argues that the equal pay apparatus is in need of radical reform. Single Equality legislation, due to be introduced in the autumn, is the ideal forum to do so. Substantively, it is essential to move beyond the current narrow range of comparison, the limited definition of equality and the lack of a collective dimension. So far as enforcement is concerned, the way forward lies in a positive duty to eliminate pay discrimination, which builds on and strengthens the current gender duty. Women's right to equal pay for equal work is often represented as an unreasonable demand on resources, carrying with it an unsustainable cost. In fact, it is a fundamental right recognised by major human rights instruments and the International Labour Organization (ILO). It is to be hoped that the Single Equality Bill will give equal pay reform the serious attention so urgently needed.
Long-Term Spatiotemporal Analysis of Social Media for Device-to-Device Networks

The popularity of personal devices has been creating a new location-based content era, where users produce, share and access content anytime and anywhere. Mobile devices in the same area can cooperate to each other by using a Device-to-Device (D2D) communication and maximize the usage of network resources and allow the creation of new applications and experiences. In this paper, we investigate the dynamics of physical proximity of peers in a long-term study. We used one year of collected data from social media for an analysis of spatiotemporal features of how users encounter each other and the opportunities for content offloading in cellular networks. The results provided insights about the regularity of encounters, the role of routine and other spatial characteristics.
Strategic Motives For International Alliance Formation

This paper considers the strategic motivation for international alliance formation for a sample of UK firms with partners in western Europe, the United States and Japan. the relative importance of a set of strategic motives is identified and related to extant theory. A parsimonious set of strategic motives for the sample studied is provided by means of factor analysis. the paper identifies the main strategic motives for alliance formation by UK firms as intrinsically linked to the market and geographical expansion of the firm and that the main strategic motives are underpinned by the theories of strategic positioning and organizational learning. This study also finds that some of the often suggested motives for alliance formation found in the literature, in particular aspects of risk reduction associated with new projects, appear not to be particularly important motivating factors. Hypotheses are tested on the relationship between the relative importance of individual strategic motives and a number of characteristics of the sample - contractual form of the alliance, relative partner size, primary geographical location of the venture, industry of the alliance and partner nationality. Implications of the findings for future theorizing on alliances and their motives is identified. Copyright 1996 Basil Blackwell Ltd.
REIT Asset Sales: Opportunistic Versus Liquidation

This study provides novel evidence that the outcome from REIT sales of office and apartment property is signaled in the transaction price managers accept relative to the fundamental value. The identification strategy recognizes opportunistic sales as sold at prices above fundamental value. Opportunistic sales are followed by positive abnormal returns, measured relative to the market and associated benchmark indices. Assets sold below fundamental value are liquidated by firms with low profitability, low cash and low investment opportunities. Discounted transactions experience zero abnormal returns. Returns following asset sales are influenced by accounting measures, the flow of funds and financial constraints.
Power Flow Analysis for Radial Distribution System Using Backward/Forward Sweep Method

— This paper proposes a backward/forward sweep method to analyze the power flow in radial distribution systems. The distribution system has radial structure and high R/X ratios. So the newton-raphson and fast decoupled methods are failed with distribution system. The proposed method presents a load flow study using backward/forward sweep method, which is one of the most effective methods for the load-flow analysis of the radial distribution system. By using this method, power losses for each bus branch and voltage magnitudes for each bus node are determined. This method has been tested on IEEE 33-bus radial distribution system and effective results are obtained using MATLAB.
Development of supplier relationship including cost of defectives in the cyclic production

In the supply chain situation, a decision regarding supplier relationship is of high importance. This usually happens on the basis of supplier company parameters. In order to satisfy the demands, a buyer company often expects the supplier company to expedite their operations, i.e., to enhance the related production rate. In this context, presently the focus of this article is on the cyclic production environment at the supplier company premises. Any practical production process is expected to generate defective products also along with the normal usable products. After an estimation of this and the costs concerning defectives, it needs to be modelled in the cyclic manufacturing. This article incorporates specifically the cost of defectives along with the other relevant costs. After developing an interest in the inclusion of these costs, the supplier company is categorised. A contribution of this article is the development of supplier relationship in the discussed environment.
Middleware requirements for collaborative unmanned aerial vehicles

With the recent advances in the aircraft technologies, software, sensors, and communications; unmanned aerial vehicles (UAVs) can offer a wide range of applications. Some of these applications may involve multiple UAVs that cooperate and collaborate to achieve a common goal. This kind of applications is termed collaborative UAVs applications. One of the main research topics for multiple UAVs is developing an effective framework to enable the development of software systems for collaborative UAVs operations. One possible approach is to rely on middleware technologies to simplify the development and operations of such applications. This paper discusses the challenges of developing collaborative UAVs applications and how middleware can help resolve some of these challenges. In addition, the paper studies the utilization of service-oriented middleware infrastructures for implementing and operating collaborative UAVs applications. Finally, the paper investigates the collaborative aspect of multiple UAVs and lists the functions needed for service-oriented middleware to satisfy the development and operations of such applications.
Trajectory tracking problem of a quad-rotor Pendulum

The quad-rotor pendulum is a multi-variable, nonlinear and non-minimum phase system. There are two main problems considered in controlling the quad-rotor pendulum: one is how to response quickly; the other is to stabilize the quad-rotor pendulum at the expected position. In order to solve these two problems, the Backstepping controller is used to realize it, the simulation results show that the proposed approach is able to robustly stabilize the quad-rotor pendulum and move it to any position.
Clozapine, but not haloperidol, reverses social behavior deficit in mice during withdrawal from chronic phencyclidine treatment

Phencyclidine (PCP) reduced social behavior (SB) in a dose- and time-dependent fashion. However, no such SB deficit was observed on repeated treatment with methamphetamine for 14 days. The SB deficit produced by treatment with PCP (10 mg/kg/day) for 14 days, which persisted for 28 days after withdrawal, was attenuated by clozapine (10 mg/kg/day) given for 7 days, whereas haloperidol for 7 days had no effect. Clozapine, but not haloperidol, alone at the same treatment dose increased SB in saline-treated mice. These results suggest that the proposed PCP model in mice will provide a tool to test beneficial effects of atypical antipsychotics on social dysfunction in schizophrenia, and contribute to our understanding of the mechanisms by which clozapine improves SB deficit.