Miracle-dz/UniFAR-FTUs huggingface dataset:
Optimization of advanced MOS technologies for narrow distribution of circuit performance

A methodology is investigated to optimize technological parameters to reduce distribution of circuit performance. Major attention is paid to treat all characteristics from device level to circuit level on one basis, namely technological parameters. The key point of the whole procedure is the quality of the analytical MOSFET model used for circuit simulations. Due to the physical description of our model, only three independent technological parameters have to be studied, namely the effective channel length, the oxide thickness, and the substrate doping concentration. These values are available directly or indirectly from measurements. The methodology is applied to optimize the oxide thickness for a 23-stage ring oscillator to obtain narrow delay distribution for low voltage application.
Fast Detection of Renal Ischemia in Transplanted Kidneys With Delayed Graft Function—An Experimental Study

Background The newly transplanted kidney is difficult to monitor with regard to postoperative vascular thrombosis, especially when there is delayed graft function. We evaluated microdialysis as a tool for early ischemia detection in porcine kidneys with delayed graft function early after transplantation. Methods Sixteen pigs were transplanted with 26-hr cold ischemia kidneys. A microdialysis catheter was placed in the lateral renal cortex. Five hours after graft reperfusion, the pigs were randomized to renal arterial clamping or open artery, n=8 in each group, and further observed for 2 hr. Results The diuresis and glomerular filtration rate were low and decreasing throughout the study, with no significant differences between groups. Until arterial clamping, there were no significant differences in the development of local renal metabolites between the two groups. Renal artery clamping immediately caused significantly different development of all metabolites (P<0.02 for all) compared to the open artery group. After clamping, levels of glutamate and glycerol were significantly increased within 30 min (P=0.0049 and P=0.0061, respectively). Conclusions Microdialysis provided an early warning of arterial occlusion in transplanted grafts with delayed graft function. It may become a valuable tool for postoperative monitoring and detection of thrombosis after renal transplantation.
Analysis of publicly disclosed information in Facebook profiles

Facebook, the most popular Online social network is a virtual environment where users share information and are in contact with friends. Apart from many useful aspects, there is a large amount of personal and sensitive information publicly available that is accessible to external entities/users. In this paper we study the public exposure of Facebook profile attributes to understand what type of attributes are considered more sensitive by Facebook users in terms of privacy, and thus are rarely disclosed, and which attributes are available in most Facebook profiles. Furthermore, we also analyze the public exposure of Facebook users by accounting the number of attributes that users make publicly available on average. To complete our analysis we have crawled the profile information of 479K randomly selected Facebook users. Finally, in order to demonstrate the utility of the publicly available information in Facebook profiles we show in this paper three case studies. The first one carries out a gender-based analysis to understand whether men or women share more or less information. The second case study depicts the age distribution of Facebook users. The last case study uses data inferred from Facebook profiles to map the distribution of worldwide population across cities according to its size.
Depression in Dhat syndrome.

AIMS AND OBJECTIVES Dhat syndrome is a widely recognized clinical condition in the Indian subcontinent characterized by excessive preoccupation with semen loss as the main presenting complaint. This condition has been considered to be a culture-bound syndrome, and depressive symptoms have previously been reported. We were interested to know how common depression is, and to quantify these features. MATERIALS AND METHODS We studied 30 patients attending the Psychiatry Outpatient Department of a tertiary care hospital for their complaints about passing of semen in urine frequently. Those with depressive symptoms were further evaluated using the fourth revision of the Diagnostic and Statistical Manual of Mental Disorders (DSM-IV) Diagnostic Criteria for Depression, and depression severity was assessed using the 17-item Hamilton Depression Rating Scale for Depression (HAM-D). Patients meeting the criteria were started on capsule fluoxetine, a selective serotonin reuptake inhibitor, in dose of 20-40 mg per day. Patients were periodically followed fortnightly and were reevaluated for therapeutic response using the HAM-D. RESULTS A total of 30 patients (age = 20-40 years; mean age = 29 years; mean age of onset = 19 years; mean duration of illness = 11 months) were studied. The majority of cases were unmarried (64.2%) and educated till 5th class or above (70%). Twenty out of 30 (66%) patients met DSM-IV Diagnostic Criteria for Depression. Ten patients (33.3%) were found to have a comorbid problem of premature ejaculation, and two patients reported erectile dysfunction (6.6%). Patients showed statistically significant therapeutic response to fluoxetine. CONCLUSION Depressive phenomenology meeting DSM-IV Diagnostic Criteria for Depression seems common in Dhat syndrome and responds to selective serotonin reuptake inhibitors along with regular counseling.
Optimal tracking by LTI controllers over scaled MIMO additive white noise channels

In this paper we study the fundamental limitations in stabilization and tracking of multi-input, multi-output (MIMO) networked feedback systems. We adopt a parallel additive white noise (AWN) model for the MIMO communication channel, and consider as our performance measure the mean square error for a system's output to track a random reference signal with finite power. Of particular interest in our study is the joint design of the controller and the channel to mitigate the requirement on feedback stabilization and to better the tracking performance. To this effect we consider scaled AWN channels, with positive diagonal scaling matrices interpreted as static coders and decoders. By casting the problem as a constrained optimal H2 control problem and employing duality principles, we derive necessary and sufficient conditions for the system to be mean-square stabilizable and analytical characterizations for the best achievable performance under channel input power constraint. While fundamental limits are known to exist, it is seen that an appropriate channel scaling can be employed to exploit the channel power effectively so as to fundamentally improve a system's stabilizability and tracking performance.
Delphinidin induces apoptosis via cleaved HDAC3-mediated p53 acetylation and oligomerization in prostate cancer cells

Delphinidin is a major anthocyanidin compound found in various fruits. It has anti-inflammatory, anti-oxidant, and various other biological activities. In this study, we identified the epigenetic modulators that mediate the apoptotic effect of delphinidin in human prostate cancer cells. We found that treatment of LNCaP cells (a p53 wild-type, human prostate cancer cell line) with delphinidin increased caspase-3, −7, and −8 activity, whereas it decreased histone deacetylase activity. Among class I HDACs, the activity of HDAC3 was specifically inhibited by delphinidin. Moreover, the induction of apoptosis by delphinidin was dependent on caspase-mediated cleavage of HDAC3, which results in the acetylation and stabilization of p53. We also observed that delphinidin potently upregulated pro-apoptotic genes that are positively regulated by p53, and downregulated various anti-apoptotic genes. Taken together, these results show that delphinidin induces p53-mediated apoptosis by suppressing HDAC activity and activating p53 acetylation in human prostate cancer LNCaP cells. Therefore, delphinidin may be useful in the prevention of prostate cancer.
Revealing Language Deficits Following Stroke: The Cost of Doing Two Things at Once

ABSTRACT The costs of doing two things were assessed for a group of healthy older adults and older adults who were tested at least 6 months after a stroke. A baseline language sample was compared to language samples collected while the participants were performing concurrent motor tasks or selective ignoring tasks. Whereas the healthy older adults showed few costs due to the concurrent task demands, the language samples from the stroke survivors were disrupted by the demands of doing two things at once. The dual task measures reveal long-lasting effects of strokes that were not evident when stroke survivors were assessed using standard clinical tools.
A Staged Memory Resource Management Method for CMP systems

Memory interference is a critical impediment to system performance in CMP systems. To address this problem, we first propose a Dynamically Proportional Bandwidth Throttling policy (DPBT), which dynamically throttles back memory-intensive applications based on their memory access behavior. DPBT achieves a more balance memory bandwidth partitioning. Moreover, we improve the previous memory channel partitioning scheme by integrating it with a bank partitioning. We further integrate DPBT with the improved memory channel partitioning scheme and a memory scheduling policy to leverage the architecture advantages, and present a Stage Memory Resource Management Method (SRM). Experimental results show that DPBT improves system throughput/fairness by 13.5%/31.1%. SRM provides 27.1% better system throughput and 34.8% better system fairness.
Effect of Fly Ash and Slag on the Interfacial Zone Between Cement and Aggregate

This paper describes how the chemical characteristics of the cement paste-aggregate interfacial zone have been considered to influence the durability and mechanical properties of concrete. Particularly, the effects of mineral admixtures such as fly ash and slag on the microstructure of the interfacial zone deserve attention. An x-ray diffraction technique was used to evaluate the amounts of Ca(OH)2, ettringite, and the orientation of Ca(OH)2 crystals in the interfacial zone. Composite specimens with several types of rocks were broken to produce a fracture surface on the cement paste prism to which the x-ray diffraction analysis was applied. The analyses showed that the addition of fly ash or slag considerably affected the peak height and orientation of Ca(OH)2 crystals in the interfacial zone, which normally extends up to 50 to 100 µm from the interface. The formation of ettringite in the vicinity of the aggregate surface was restricted by the addition of the admixtures. These results also suggest that the addition of the mineral admixtures favorably affects the resistance of the interfacial zone against aggressive agents from the surroundings. The x-ray fluorescence analysis was conducted to quantify calcium and silicon in the zone. The results obtained complemented the conclusions described previously.
Metabolic and molecular changes associated with the increased skeletal muscle insulin action 24-48 h after exercise in young and old humans.

The molecular and metabolic mechanisms underlying the increase in insulin sensitivity (i.e. increased insulin-stimulated skeletal muscle glucose uptake, phosphorylation and storage as glycogen) observed from 12 to 48 h following a single bout of exercise in humans remain unresolved. Moreover, whether these mechanisms differ with age is unclear. It is well established that a single bout of exercise increases the translocation of the glucose transporter, GLUT4, to the plasma membrane. Previous research using unilateral limb muscle contraction models in combination with hyperinsulinaemia has demonstrated that the increase in insulin sensitivity and glycogen synthesis 24 h after exercise is also associated with an increase in hexokinase II (HKII) mRNA and protein content, suggesting an increase in the capacity of the muscle to phosphorylate glucose and divert it towards glycogen synthesis. Interestingly, this response is altered in older individuals for up to 48 h post exercise and is associated with molecular changes in skeletal muscle tissue that are indicative of reduced lipid oxidation, increased lipogenesis, increased inflammation and a relative inflexibility of changes in intramyocellular lipid (IMCL) content. Reduced insulin sensitivity (insulin resistance) is generally related to IMCL content, particularly in the subsarcolemmal (SSL) region, and both are associated with increasing age. Recent research has demonstrated that ageing per se appears to cause an exacerbated lipolytic response to exercise that may result in SSL IMCL accumulation. Further research is required to determine if increased IMCL content affects HKII expression in the days after exercise in older individuals, and the effect of this on skeletal muscle insulin action.
Participatory Design that Matters—Facing the Big Issues

At a time where computer technology is putting human lives and work under pressure, we discuss how to provide alternatives. We look back at Participatory Design (PD) which was originally about possibilities and alternatives as much as it was about specific solutions. The paper aims to revitalize and revise PD to help people influence big issues. The agenda for this is set through proposing a set of key elements for realizing new, important possibilities. We discuss the possible changes of partnership with users, call for a new role of researchers as activists, debate how to work with demanding visions for lasting impact, and democratic control. We focus on high technological ambitions, on deployment of working prototypes, on alliances, and on scaling up, all seen as important for a PD that matters. We conclude the paper with an invitation to participate in the continued discussion, codesign, and realization of a PD that matters.
Comparative Results of Transurethral Incision with Transurethral Tesection of the Prostate in Renal Transplant Recipients with Benign Prostate Hyperplasia

Purpose The aim of this study is to compare the results of transurethral incision of the prostate (TUIP) and transurethral resection of the prostate (TURP) for the surgical treatment of benign prostate hyperplasia (BPH) in patients with renal transplantation. Materials and Methods Between April 2009 and May 2016, BPH patients with renal transplants whose prostate volumes were less than 30 cm3 were treated surgically. Forty-seven patients received TURP and 32 received TUIP. The patients' age, duration of dialysis, duration between transplant and TURP/TUIP, preoperative and postoperative serum creatinine (SCr), International Prostate Symptom Score (IPSS), maximum flow rate (Qmax) and postvoid residual volume (PVR) were recorded. At 1-,6- and 12-month follow-up, early and long-term complications were assessed. Results were evaluated retrospectively. Results In both groups, SCr, PVR and IPSS decreased significantly after the operation, while Qmax and increased significantly (P<.001). There was no difference between the two groups in terms of increase in Qmax and decrease in IPSS, SCr and PVR (P=.89, P=.27, P=.08, and P=.27). Among postoperative complications, urinary tract infection (UTIs) and retrograde ejaculation (RE) rates were higher in the TURP group than the TUIP group (12.7% versus 6.2% and 68.1% versus 25%,respectively), whereas urethral strictures were more prevalent in the TUIP group (12.5% versus 6.3%). Conclusion For the treatment of BPH in renal transplant patients with a prostate volume less than 30 cm3, both TUIP and TURP are safe and effective.
Effect of low‐temperature processing on dry film photoresist properties for flexible electronics

This study presents the mechanical characterization of the dry film photoresist PerMX and its adhesion properties when laminated onto Kapton (R) E (PI) and Melinex (R) ST506 (PET). Additionally, the processing temperature, the adhesion strength, and the neutral plane position are investigated and optimized. A relatively low-temperature (85 degrees C) process is developed to protect the integrity of the polymers with low glass transition temperature and reduce the thermal mismatch stress. Reduction in processing temperature led to a decrement in the adhesion strength. To counteract this unwanted effect, surface treatments (oxygen plasma) are performed on the polymer surface before lamination. Using the latter techniques, adhesion of PerMX to PET (hard bake: 1 h at 85 degrees C) is increased from 0.07 to 0.26 N mm1 (variation of 270%). Finally, the mechanical robustness is investigated and increased by tuning the position of the neutral plane, after 50,000 bending cycles and a radius of curvature of 2.5 mm. (c) 2013 Wiley Periodicals, Inc. J Polym Sci Part B: Polym Phys, 2013
A Study on Measurement of Tourism Environmental Carrying Capacity of Geoparks - A Case Study of Xinwen Karst World Geopark

Scientific assessment of tourism environmental carrying capacity is key to geotourism sustainable development. Based on exploring the definition of tourism environmental carrying capacity of geoparks and its characteristics, by adopting methods of AHP and literature review this paper focuses on establishing an appraisal indicator system of tourism environmental carrying capacity of geoparks. However, its more reasonable to give weights of appraisal indicators for a given geopark for geoparks greatly differ in terms of natural, economical and socio-cultural environment. Thus, taking Xinwen Karst World Geopark in Sichuan province as an example, the paper calculates weights of indicators of the parks tourism carrying capacity with AHP method and measures its tourism environmental carrying capacity by using average weighted method. The findings reveal that Xinwen Karst World Geopark is in mild overloading.
An Investigation of the Needs on Educational Robots

Robot has been receiving increasing attention and robot in education is considered a promising aid for teaching and learning in many ways. This study attempts to investigate the need of the educational robot among six different user groups (pre-school user, primary school user, high school user, college user, adult user and elderly user). A triangulation technique was applied for cross validation, including systematic literature review, experts' interview and instructors' survey. It is expected that through this research the need of educational robot for six user groups can be clearly identified and to propose future directions for the development of educational robots.
The Actual (Un)usefulness of the Bologna System in Medical Education

Introduction: Faculty of Medicine, University of Sarajevo has officially started working on 22.11. 1944, and is the oldest faculty in the medical field in Bosnia and Herzegovina. At the same time there are two systems of organization of the teaching process, the old system and the Bologna system. Aim: To analyze the implementation of the Bologna system, and making an overview of its justification. Material and methods: Answers from questionnaires from total of 459 students were analyzed (197 who had studied under the old system and 262 who studied under the Bologna system), so total of four generations of the Bologna system. They filled out a questionnaire in which they evaluated the teaching process. Student’s opinion about quality of medical education was measured by modified Lickert scale. Results: Students of old system are older than students of the Bologna process, whose average age is increasing from generation to generation, given the growing number of students who repeat a year. All students of old system repeated an academic year once or several times (p <0.05). Analysis of average grades showed statistically significant difference (p <0.05), where students in the Bologna system had higher averages than students who were studying under the old system. The presence of large number of female students, in both systems is significant (p <0.05). Out of 33 questions about satisfaction of class, 15 were answered with better average grade from students of the Bologna system. A slight improvement in the Bologna system is in terms of the evaluation of the quality of the educational process (teachers, methods, effects). The only significant progress has been proven in terms of rating the degree of computerization of the educational process–general records on enrolled students (old system vs Bologna system–3,44 vs 3,63), record of attendance (3,47 vs 3,73), obtaining certificates (3,08 vs 3,84), method of registration of exam (2,98 vs 3,71), method of practical exam (3,06 vs 3,36) and theoretical methods of taking exam (3,01 vs 3,14). Average grades where no average grade, on any issue, does not reach grade 4 of Likert Scale, talks about real problems of education in medical field. Conclusion: In a relatively large sample (four generations of students) true benefit and progress of the Bologna system has not been proven, in comparison to the old system. Bologna system has eased the students in the administrative sense by introduction of computerization of faculties, but the old problems and old questions about the organization’s process and delivery have not been eliminated.
An Identification Decision Tree Learning Model for Self-Management in Virtual Radio Access Network: IDTLM

Along with the blowout of new applications and the integration of the heterogeneous networks platforms in the future Internet of everything, the self-management of virtual radio access network is of significant importance. The urgent problem needed to be solved for the self-management in virtual radio access network is the match of application and virtual service (tailored service of virtual functions for the application). In this paper, an identification decision tree learning model (IDTLM) based on transfer learning has been proposed. First, we do research on the redundant problem of the traditional packet decision trees and reduce the dimensionality of features by a proximal gradient descent method and clustering the features by Lagrange’s multiplier, so as to improve the online matching speed between applications and virtual service. And then, in consideration of the independent and non-identical distribution among online and trained data, and the possible change of virtualized network platform, a method of transfer learning is proposed to improve the quality of generalization for IDTLM. Finally, online test is done for IDTLM, and the result shows that the accuracy rate of trained applications can reach 99% and the accuracy rate can reach 96% if untrained applications are included. Meanwhile, theoretical analysis has been carried out for the transfer of IDTLM. The analysis shows that IDTLM system is of high recognizing speed and low false positive rate and it could adapt to the transfer of different scenarios.