Miracle-dz/UniFAR-FTUs huggingface dataset:
Axillary Hyperhidrosis Treatment by Simple Skin Excision and Undermining

The current literature of axillary hyperhidrosis is reviewed. Excision of the gland-containing skin of the axilla has been a mainstay in the treatment of axillary hyperhidrosis for many years. A retrospective study was performed using data accumulated from 56 consecutive patients who underwent a surgical procedure modified from that originally described by Hurley and Shelley. Excision of the hair-bearing portion of the axilla with undermining of the adjacent skin and simple closure was performed under local or general anesthesia. Ninety-two per cent of patients were satisfied with the results. Five patients wished to undergo a second procedure, either because they still had excessive perspiration or because they were unhappy with their scars. Complication rates were low and were compared with other series. Thus, the described procedure provides a simple, safe and effective modality for the treatment of axillary hyperhidrosis.
Silent UX? Erfassung der User Experience von intelligenten Heimanwendungen

Vernetzte Gerate dringen immer weiter in unseren Alltag vor. Die mit ihnen propagierte ortliche Entkoppelung des Nutzers vom Produktstandort stellt bestehende Usability- und User-Experience-Methoden vor Probleme. Daher wird hier untersucht, ob psychophysiologi-sche Methoden die Erfassung des Interaktionserlebnisses erlauben. Am Beispiel eines intelligenten Lautsprechers wird getestet, ob das Stresser-leben, der kognitive Workload sowie die Emotionen wahrend der Produkt-interaktion gleichzeitig mittels psychophysiologischen Masen erfasst wer-den konnen. Diese Studie erweitert bestehende Befunde zum Einsatz von psychophysiologischen Masen zur Erfassung des Nutzungserlebens und bietet eine gute Grundlage zur Echtzeiterfassung des Nutzererlebens.
CERTAIN ASPECTS REGARDING THE FINANCIAL-ECONOMIC COMMUNICATION IN THE AGRICULTURE SECTOR

The information and especially the economic information today is present in all the domains of activity, being an indispensable element of the progress and use in the managerial process of the accounting information is an imperative necessity of our present days. [1] Globalization means an intensification of the economic, political, social and cultural relationships over the national borders, in this sense it means more and more the geographic extension of a wide range of phenomena and aspects. [5]The efficient management of the activity of each economic entity wherever it is placed, and knowing the results obtained, including the aspects related to the final results, are possible in the current activity through the analysis of the data provided by the financial statements. [2], [6] We could say that concerning the financial reporting of the information concerning the activity of various economic entities is extremely important and necessary for the creation of unique rules at international level; [4] rules requested especially by the concept conflicts appeared between those that draw up the financial statements on one hand and the ones that use the provided information on the other hand. [3]
'Remedying' the Remedy System for Prohibited Subsidies in the WTO: Reconsidering Its Retrospective Aspect

The problem of delayed implementation in prohibited subsidy disputes is a persistent problem in the WTO dispute settlement system. This article examines the WTO remedy system for enforcing WTO rulings in prohibited subsidy disputes to suggest some ways to improve the currently “ineffective” WTO dispute settlement mechanism, at least for resolving disputes involving prohibited subsidies promptly. Through a more detailed study of the WTO remedy system in action, several shortcomings and loopholes in the WTO jurisprudence involving prohibited subsidies are identified and analyzed. In particular, issues involving the “appropriate” level of retaliation, the meaning of “withdrawal” of a subsidy, and the prolonged dispute proceedings in contrast to the requirement to remove illegal subsidy measures “without delay” are analyzed in more detail. Applying the discussions on the principle of proportionality, and the different purpose of remedies, this article suggests that the “retrospective” application of the retaliation remedy should be introduced for effectively addressing non-recurring prohibited subsidies under the WTO system. On the other hand, the remedy of monetary compensation is not a viable option as a retrospective remedy for prohibited subsidies, while the existing “fast track” procedure in place for prohibited subsidies needs to be improved in application through broadened jurisdiction of compliance panels.
MAC Performance Analysis for Drive-Thru Internet Networks With Rayleigh Capture

In practical radio transmissions, channel capture is a dominating factor that affects wireless network performance. The capture effect can occur in wireless network when packets arrive with different powers. Packets with high power can effectively swamp low power packets, such that they are received successfully, when otherwise a collision would have occurred. We present a vehicular network performance-prediction model for a Rayleigh capture channel in Drive-thru Internet scenario. The model incorporates the capture effect into a 2-D Markov chain modeling the high-node mobility and distributed coordination function broadcast scheme. The performance-prediction model unveils the impacts of mobility velocity and number of vehicles on the throughput in a Rayleigh capture channel. We use a vehicular traffic flow model to predict vehicular movement on road by aggregating all vehicles into a flow. Simulation results confirm that our performance-prediction model accurately predicts the performance of traveling vehicles with Rayleigh capture channel in the Drive-thru Internet scenario. We demonstrate that using our performance-prediction model, we can obtain optimal contention window value, by which the best system throughput can be reached without wasting contention time. This is also proved by Anastasi et al.
Intercomparison and uncertainty analysis of global MODIS, cyclopes, and GLOBCARBON LAI products

Three major global moderate resolution leaf area index (LAI) products: MODIS/TERRA+AQUA (MCD15 C5), SPOT/VEGETATION CYCLOPES V3.1, and the GLOBCARBON V2.0, were compared in this study. Results show that the three products agree very well for grasses/cereal crops and shrubs. The products differ considerably for EBF, where GLOBCARBON shows systematically lower LAIs than MODIS (~1.02) and CYCLOEPS (~0.50). The discrepancies for EBF are attributed to the different LAI definitions and clumping corrections. MODIS and CYCLOPES generally agree with each other for DBF, ENF and DNF during the peak growth period. The product theoretical uncertainties, indicated by the quantitative quality indicators (QQIs), show that MODIS has the lowest uncertainty (0.19) followed by CYCLOPES (0.54) and GLOBCARBON (0.65).
Research on the Motion Picture Industry: State of the Art and New Directions Off the Beaten Track Away from Theatrical Release

The motion picture industry has been subject of extensive academic research over the last decades. However, most scholars focused on the U.S. theatrical motion picture market. The number of research activities regarding even more profitable release windows, such as home video or television, has been substantially lower. Although international distribution is essential for a motion picture project to break even, there has been little significant re-search on most other markets. This paper aims at summarizing the current state of research on the motion picture industry, particularly from marketing and management perspective, revealing research gaps, and proposing recommendations for future research endeavors. Therefore, a three-pillar scheme is developed to systemize previous findings: Research on intraorganizational decision making, contractual relationships between national stakeholders, and international market competition are differentiated. Since these insights are mainly derived from U.S. theatrical exhibition, they can hardly be applied to other markets and exhibition windows. Thus, potential research areas are identified to expand knowledge of posttheatrical and international markets.
Precautionary Storage in Electricity Markets

As renewable energy depends on meteorological shocks and is non-controllable, the overall energy production becomes riskier with the rising renewable share. Although this has led to a renewed interest in storage technologies, not much consideration has been given to energy storage due to precautionary motives. In our study, we look at to what extent a convex marginal utility (prudence) and a convex marginal cost (frugality) can spur precautionary energy storage. We set up a simple theoretical model of energy consumption and production with intermittent renewable sources, dispatchable systems, and energy storage. First, we characterize the optimum and demonstrate how prudence and frugality can lead to higher levels of energy storage. By applying our findings to perfectly competitive markets, we further show that prudence and frugality increase the market energy price through higher demand for energy storage and decrease price volatility. Our analysis can have implications for inventory decisions in various other industries where firms face capacity constraints and are exposed to production risks.
Proteolytic cleavage by neutrophil elastase converts inactive storage proforms to antibacterial bactenecins.

Bac5 and Bac7, antibiotics of the bactenecin (proline/arginine-rich peptide) family, are stored as proforms in the large granules of bovine neutrophils [Zanetti, M. , Litteri, L. , Gennaro, R. , Horstmann, H. and Romeo, D. (1990) J. Cell Biol. 111, 1363-1371]. These proforms have been purified to homogeneity from granule extracts by immunoaffinity and reverse-phase chromatography. While mature bactenecins efficiently kill Escherichia coli, Klebsiella pneumoniae and Salmonella typhimurium with minimal inhibitory concentrations of 6-12 micrograms/ml, proBac5 and proBac7 do not affect the growth of the same microorganisms, even at 500 micrograms/ml. Previous investigations have suggested that the conversion of probactenecins into mature antimicrobial peptides is catalyzed by a neutral serine protease stored in the azurophil granules. Purified proBac5 and proBac7 were thus treated with elastase, cathepsin G or proteinase 3, which constitute the pool of neutral serine proteases of the azurophils, and the reaction products were identified by Western blot analysis, mass spectrometry, and N-terminal sequence analysis. Of the three proteases, only elastase is able to catalyze the stepwise cleavage of probactenecins into the corresponding mature peptides, which have the same mass, N-terminal sequence and antibiotic activity of authentic Bac5 and Bac7. These results point to the importance of cooperation between azurophils and large granules in mounting a defense reaction.
PANFIS++: A Generalized Approach to Evolving Learning

The concept of evolving intelligent system (EIS) provides an effective avenue for data stream mining because it is capable of coping with two prominent issues: online learning and rapidly changing environments. We note at least three uncharted territories of existing EISs: data uncertainty, temporal system dynamic, redundant data streams. This book chapter aims at delivering a concrete solution of this problem with the algorithmic development of a novel learning algorithm, namely PANFIS++. PANFIS++ is a generalized version of the PANFIS by putting forward three important components: 1) An online active learning scenario is developed to overcome redundant data streams. This module allows to actively select data streams for the training process, thereby expediting execution time and enhancing generalization performance, 2) PANFIS++ is built upon an interval type-2 fuzzy system environment, which incorporates the so-called footprint of uncertainty. This component provides a degree of tolerance for data uncertainty. 3) PANFIS++ is structured under a recurrent network architecture with a self-feedback loop. This is meant to tackle the temporal system dynamic. The efficacy of the PANFIS++ has been numerically validated through numerous real-world and synthetic case studies, where it delivers the highest predictive accuracy while retaining the lowest complexity.
Work stress, poor recovery and burnout in teachers.

BACKGROUND Both work stress and poor recovery have been shown to contribute to the development of burnout. However, the role of recovery as a mediating mechanism that links work stress to burnout has not been sufficiently addressed in research. AIMS To examine recovery as a mediator in the relationship between work stress and burnout among teachers. METHODS A cross-sectional study of Finnish primary school teachers, in whom burnout was measured with the Maslach Burnout Inventory-General Survey and work stress was conceptualized using the effort-reward imbalance (ERI) model. Recovery was measured with the Recovery Experience Questionnaire and the Jenkins Sleep Problems Scale. Multiple linear regression analyses and bootstrap mediation analyses adjusted for age, gender and total working hours were performed. RESULTS Among the 76 study subjects, high ERI was associated with burnout and its dimensions of exhaustion, cynicism and reduced professional efficacy. Poor recovery experiences, in terms of low relaxation during leisure time, partially mediated the relationship between ERI and reduced professional efficacy. Sleep problems, in the form of non-restorative sleep, partially mediated the relationship between ERI and both burnout and exhaustion. CONCLUSIONS Supporting a balance between effort and reward at work may enhance leisure time recovery and improve sleep quality, as well as help to reduce burnout rates.
CASH FLOWS MANAGEMENT AT THE ENTERPRISE LEVEL

The management of cash flows associates equally to the management of cash inflows and outflows, as well as to the administration of cash deficit or surplus. The biggest challenge from the enterprise point of view is to schedule adequately cash inflows and outflows to avoid shortages and ensure a rhythmic development of the enterprise. Article’s importance arises from the role that management of cash flows has in the daily operations of an enterprise and the issue of ensuring economic efficiency of the decision to finance financial flows. Any activity requires spending money and should be conducted in such a way as to ensure sufficient financial flows. Author comes with a vision of factors that must be analyzed to ensure the financial equilibrium of the enterprise. The researched theme includes an analysis of the effectiveness of management of financial flows aimed at the enterprise level and presents a high level of originality, as it allows combining different concepts of financial management for the analysis and management of cash flows. Qualitative research techniques are used which facilitate the research perspective, enabling a deeper understanding of the investigated problem and the obtained information have a high degree of competence.
Use of Smear-Positive Samples To Assess the PCR-Based Genotype MTBDR Assay for Rapid, Direct Detection of the Mycobacterium tuberculosis Complex as Well as Its Resistance to Isoniazid and Rifampin

ABSTRACT Isoniazid (INH) and rifampin (RIF) are two of the most important antituberculosis drugs, and resistance to both of these drugs can often result in treatment failure and fatal clinical outcome. Resistance to these two first-line drugs is most often attributed to mutations in the katG, inhA, and rpoB genes. Historically, the identification and testing of the susceptibility of Mycobacterium tuberculosis complex (MTBC) strains takes weeks to complete. Rapid detection of resistance using the PCR-based Genotype MTBDR assay (Hain Lifescience GmbH, Nehren, Germany) has the potential to significantly shorten the turnaround time from specimen receipt to reporting of results of susceptibility testing. Therefore, the aim of the present study was to determine (i) the sensitivity and accuracy of the Genotype MTBDR assay for the detection of MTBC strains and (ii) the ability of the assay to detect the presence of INH and RIF resistance-associated mutations in katG and rpoB from samples taken directly from smear-positive clinical specimens. The results were compared with those obtained with the reference BACTEC 460TB system combined with standard DNA sequencing analysis methods for katG, inhA, and rpoB. A total of 92 drug-resistant and 51 pansusceptible smear-positive specimens were included in the study. The Genotype MTBDR assay accurately and rapidly detected MTBC strains in 94.4% of the 143 specimens and showed a sensitivity of 94.4% for katG and 90.9% for rpoB when used directly on smear-positive specimens. The assay correctly identified INH resistance in 48 (84.2%) of the 57 specimens containing strains with resistance to high levels of INH (0.4 μg/ml) and RIF resistance in 25 (96.2%) of the 26 specimens containing RIF-resistant strains.
Use of ELISA, IF A, and A vidin-Biotin Staining for the Diagnosis of Bovine Genital Campylobacteriosis

Acid glycine extract (AGE) and whole cell (WC) antibodies wer e used in ELISA testing for the detection of Campylobacter fetus subsp. venerealis and subsp. fetus antibodies in the blood sera of 150 female cattle and 100 bulls which wer e one year old or older . It was observed that AGE antibody was mor e specific than WC antibody . A cr oss r eaction was detected between C. fetus subsp. venerealis and subsp. fetus. Thus, it was concluded that for Campylobacter ELISA could only be used as a monitoring test. In dir ect diagnosis of C. fetus with the Indir ect Flur escent Antibody T est and A vidin-Biotin Staining, 36% and 31.2% positivity wer e detected in 125 samples of vaginal mucus. 42% and 40% positivity wer e detected with the same test in 100 samples of pr eputial fluid. The differ ences of 5% and 2% between the two positivity values wer e not found to be statistically significant. The AB me thod is suggested for dir ect diagnosis.
Meayamycin inhibits pre–messenger RNA splicing and exhibits picomolar activity against multidrug-resistant cells

FR901464 is a potent antitumor natural product that binds to the splicing factor 3b complex and inhibits pre-mRNA splicing. Its analogue, meayamycin, is two orders of magnitude more potent as an antiproliferative agent against human breast cancer MCF-7 cells. Here, we report the picomolar antiproliferative activity of meayamycin against various cancer cell lines and multidrug-resistant cells. Time-dependence studies implied that meayamycin may form a covalent bond with its target protein(s). Meayamycin inhibited pre-mRNA splicing in HEK-293 cells but not alternative splicing in a neuronal system. Meayamycin exhibited specificity toward human lung cancer cells compared with nontumorigenic human lung fibroblasts and retained picomolar growth-inhibitory activity against multidrug-resistant cells. These data suggest that meayamycin is a useful chemical probe to study pre-mRNA splicing in live cells and is a promising lead as an anticancer agent. [Mol Cancer Ther 2009;8(8):2308–18]
Performance ratio-based coherent risk measure and its application

Utilizing a specific acceptance set, we propose in this paper a general method to construct coherent risk measures called the generalized shortfall risk measure. Besides some existing coherent risk measures, several new types of coherent risk measures can be generated. We investigate the generalized shortfall risk measure’s desirable properties such as consistency with second-order stochastic dominance. By combining the performance evaluation with the risk control, we study in particular the performance ratio-based coherent risk (PRCR) measures, which is a sub-class of generalized shortfall risk measures. The PRCR measures are tractable and have a suitable financial interpretation. Based on the PRCR measure, we establish a portfolio selection model with transaction costs. Empirical results show that the optimal portfolio obtained under the PRCR measure performs much better than the corresponding optimal portfolio obtained under the higher moment coherent risk measure.
UV radiation facilitates methotrexate resistance and amplification of the dihydrofolate reductase gene in cultured 3T6 mouse cells

Pretreatment of 3T6 murine cells with the carcinogen UV radiation or N-acetoxy-N-acetylaminofluorene increased the number of methotrexate-resistant colonies. This carcinogen-induced enhancement was seen only at low toxicities. The enhancement was transient and was observed at its maximum when cells were subjected to methotrexate selection 12 to 24 h after treatment. The addition of a tumor-promoting agent, 12-O-tetradecanoylphorbol-13-acetate, during or after carcinogen treatment further enhanced this effect. A large proportion of the resistant colonies had an increase in the dihydrofolate reductase gene copy number and the relative proportions of colonies with amplified genes were similar, regardless of whether selected cells were untreated, treated with carcinogen, or treated with carcinogen plus promoter. We discuss some of the variables which both enhance the generation and improve the detection of methotrexate-resistant colonies, as well as certain implications of our results for the generation and mechanism of gene amplification.
Lattice-valued fuzzy turing machines and their computing power

In this paper, fuzzy Turing machines with membership degrees in distributive lattices, which are called lattice-valued fuzzy Turing machines, are studied. First several formulations of lattice-valued fuzzy Turing machines, including in particular deterministic and nondeterministic lattice-valued fuzzy Turing machines (l-DTMcs and l-NTMs), are given. It is shown that l-DTMcs and l-NTMs are not equivalent as the acceptors of fuzzy languages. This contrasts sharply with classical Turing machines. Second, it is shown that lattice-valued fuzzy Turing machines can recognize n-r.e. sets in the sense of Bedregal and Figueira, the super-computing power of fuzzy Turing machines is established in the lattice-setting. Third, it is demonstrated that the truth-valued lattice being finite is a necessary and sufficient condition for the existence of a universal lattice-valued fuzzy Turing machine. For an infinite distributive lattice with a compact metric, it is declared that a universal fuzzy Turing machine exists in an approximate sense. This means, for any prescribed accuracy, there is a universal machine that can simulate any lattice-valued fuzzy Turing machine on it with the given accuracy.