Miracle-dz/UniFAR-FTUs huggingface dataset:
The effect of stimulating immigrant and national pupils’ helping behaviour during cooperative learning in classrooms on their maths‐related talk

This study examined whether stimulation of immigrant and national pupils’ use of high‐quality helping behaviour (experimental condition) during cooperative learning (CL) in classrooms boosts their maths‐related talk more than in an educational situation in which such stimulation is largely absent (control condition). A total of 59 elementary‐age pupils enrolled in a CL maths curriculum of 11 lessons. They were video taped during two lessons while working together on maths assignments to assess their maths‐related talk. We found that the quality of maths‐related talk was higher in the experimental condition. Furthermore, immigrant pupils’ used less maths‐related talk than the national pupils. Implications are discussed.
Relationships of Alcohol Use and Alcohol Problems to Probable Anxiety and Mood Disorder

We examine the effects of alcohol consumption and problem drinking on probable anxiety and mood disorder (AMD). Data were taken from the 2000–2006 CAMH Monitor (N = 15,653) general population survey of Ontario adults. Scoring 4+ on the 12-item General Health Questionnaire defined probable AMD, as suggested by recent research. Logistic regression showed that respondents with alcohol problems had significantly increased odds of probable AMD, but those reporting moderate daily alcohol consumption (up to 2 drinks) had decreased odds of probable AMD compared to abstainers. These data replicate other recent research in suggesting that the relationship between alcohol and adverse psychological states, such as psychological distress and probable anxiety and mood disorder, may not be monotonic. Several ways in which selection bias could account for these findings are discussed, as well as other possible causative mechanisms.
A comparative analysis of low-power low-voltage dual-edge-triggered flip-flops

This paper compares four previously published static dual-edge-triggered flip-flops (DETFFs) with a proposed design for their performance, power dissipation, and low-voltage low-power applications. For each DETFF, the optimal delay, power consumption, and power-delay product are determined as the primary figures of merit. The proposed design is shown to have the least energy at low voltages.
The economic burden of depression in 1990.

BACKGROUND We estimate in dollar terms the economic burden of depression in the United States on an annual basis. METHOD Using a human capital approach, we develop prevalence-based estimates of three major cost-of-illness categories: (1) direct costs of medical, psychiatric, and pharmacologic care; (2) mortality costs arising from depression-related suicides; and (3) morbidity costs associated with depression in the workplace. With respect to the latter category, we extend traditional cost-of-illness research to include not only the costs arising from excess absenteeism of depressed workers, but also the reductions in their productive capacity while at work during episodes of the illness. RESULTS We estimate that the annual costs of depression in the United States total approximately $43.7 billion. Of this total, $12.4 billion-28%-is attributable to direct costs, $7.5 billion-17%-comprises mortality costs, and $23.8 billion-55%-is derived from the two morbidity cost categories. CONCLUSION Depression imposes significant annual costs on society. Because there are many important categories of cost that have yet to be estimated, the true burden of this illness may be even greater than is implied by our estimate. Future research on the total costs of depression may include attention to the comorbidity costs of this illness with a variety of other diseases, reductions in the quality of life experienced by sufferers, and added out-of-pocket costs resulting from the effects of this illness, including those related to household services. Finally, it may be useful to estimate the additional costs associated with expanding the definition of depression to include individuals who suffer from only some of the symptoms of this illness.
Learning-Based Precool Algorithms for Exploiting Foodstuff as Thermal Energy Reserve

Refrigeration is important to sustain high foodstuff quality and lifetime. Keeping the foodstuff within temperature thresholds in supermarkets is also important due to legislative requirements. Failure to do so can result in discarded foodstuff, a penalty fine to the shop owner, and health issues. However, the refrigeration system might not be dimensioned to cope with hot summer days or performance degradation over time. Two learning-based algorithms are therefore proposed for thermostatically controlled loads, which precools the foodstuff in display cases in an anticipatory manner based on how saturated the system has been in recent days. A simulation model of a supermarket refrigeration system is provided and evaluation of the precool strategies shows that negative thermal energy can be stored in foodstuff to cope with saturation. A system model or additional hardware is not required, which makes the algorithms easy to implement in existing systems.
Delivering effective therapeutic interventions for men with severe personality disorder within a high secure prison

Abstract The Fens Unit is a government-initiated facility for male prisoners reaching criteria for Dangerous and Severe Personality Disorder (DSPD). Prisoners are assessed using a standardised process; those meeting criteria engage in a five-year treatment programme using a cognitive interpersonal model. Personality disorder is seen as a combination of coping strategies, developed in response to experience, which results in dysfunctions of thinking, feeling, behaviour and interpersonal relationships. These dysfunctions are linked to offending. Therefore, in order to reduce risk, multiphasic interventions – individual and group therapies – specifically target each dysfunction area, focusing on the developmental experiences that generated them. Each man's individual risk factors become treatment targets that are addressed in every aspect of the programme. All staff on the unit, clinical and operational, attempt to improve the quality of interpersonal relationships the prisoner has access to in order to create remedial experiences that are necessary to attain the capacity to develop socially adaptive cognitive, emotional and behavioural responses. This paper describes the treatment provided to these prisoners and the outcomes for the first cohort to have completed treatment (n=18). Results indicate that there is a reduction in violent behaviour, a higher than expected attendance at therapy, a decrease in actuarial risk measures and the majority of men are successfully managed in lower security after programme completion.
Preparing IS Students to Deal with Ethical Issues

The recent series of ethics violations in business (e.g., insider trading) has caused a number of firms to begin courses in ethics for employees. Unless professionals improve their ethical practices, legislation will force them to do so. The ACM and DPMA curriculum recommendations include ethics topics. An important issue is the proper education of IS students to deal with on-the-job ethical situations. Unfortunately, ethics education gets lost among the myriad of subjects to be taught in IS courses. But there is an effective pedagogical approach for this material. The approach requires students to determine how they would act in various ethical scenarios. This "personalization" method may be the first step toward proper ethical behavior in the workplace. While not a rigorous scientific treatment of the subject, the classroom experiences reported here may be helpful for IS faculty and IS trainers as they develop improved ethics instruction.
Personalizing protein nourishment

ABSTRACT Proteins are not equally digestible—their proteolytic susceptibility varies by their source and processing method. Incomplete digestion increases colonic microbial protein fermentation (putrefaction), which produces toxic metabolites that can induce inflammation in vitro and have been associated with inflammation in vivo. Individual humans differ in protein digestive capacity based on phenotypes, particularly disease states. To avoid putrefaction-induced intestinal inflammation, protein sources, and processing methods must be tailored to the consumer's digestive capacity. This review explores how food processing techniques alter protein digestibility and examines how physiological conditions alter digestive capacity. Possible solutions to improving digestive function or matching low digestive capacity with more digestible protein sources are explored. Beyond the ileal digestibility measurements of protein digestibility, less invasive, quicker and cheaper techniques for monitoring the extent of protein digestion and fermentation are needed to personalize protein nourishment. Biomarkers of protein digestive capacity and efficiency can be identified with the toolsets of peptidomics, metabolomics, microbial sequencing and multiplexed protein analysis of fecal and urine samples. By monitoring individual protein digestive function, the protein component of diets can be tailored via protein source and processing selection to match individual needs to minimize colonic putrefaction and, thus, optimize gut health.
Methylene blue microbubbles as a model dual-modality contrast agent for ultrasound and activatable photoacoustic imaging

Abstract. Ultrasound and photoacoustic imaging are highly complementary modalities since both use ultrasonic detection for operation. Increasingly, photoacoustic and ultrasound have been integrated in terms of hardware instrumentation. To generate a broadly accessible dual-modality contrast agent, we generated microbubbles (a standard ultrasound contrast agent) in a solution of methylene blue (a standard photoacoustic dye). This MB2 solution was formed effectively and was optimized as a dual-modality contrast solution. As microbubble concentration increased (with methylene blue concentration constant), photoacoustic signal was attenuated in the MB2 solution. When methylene blue concentration increased (with microbubble concentration held constant), no ultrasonic interference was observed. Using an MB2 solution that strongly attenuated all photoacoustic signal, high powered ultrasound could be used to burst the microbubbles and dramatically enhance photoacoustic contrast (>800-fold increase), providing a new method for spatiotemporal control of photoacoustic signal generation.
Assessment of the universality and utility of a set of conserved mitochondrial COI primers in insects

A set of mitochondrial COI primers has been studied by genomic PCR and many primer combinations shown to work universally well across Insects. They are able to amplify various amplicons with different variability which enables the selection of a particular amplicon as a suitable DNA marker for a project. The potential usefulness of different amplicons is examined, with analysis on published study cases employing these regions. With respect to their variability, amplicons UEA5/UEA6, UEA7/UEA8 and UEA5/UEA8 could be useful for low‐ to mid‐level phylogenetic analysis, i. e. from species, genus to‐perhaps family level depending on taxa involved. UEA5/UEA6 will be too conserved for intraspecific studies. Amplicons UEA3/UEA4 and UEA9/UEA10 would be better suited to low‐level phylogenetic investigations, such as analysis of relationships among closely related species and population genetic studies. However, these guidelines should not be over‐generalized for the reasons given. Amplification conditions of various primer combinations, and general problems in the use of conserved PCR primers are discussed.
Hydrogen Sulfide Mediates Cardioprotection Through Nrf2 Signaling

Rationale: The recent emergence of hydrogen sulfide (H2S) as a potent cardioprotective signaling molecule necessitates the elucidation of its cytoprotective mechanisms. Objective: The present study evaluated potential mechanisms of H2S-mediated cardioprotection using an in vivo model of pharmacological preconditioning. Methods and Results: H2S (100 &mgr;g/kg) or vehicle was administered to mice via an intravenous injection 24 hours before myocardial ischemia. Treated and untreated mice were then subjected to 45 minutes of myocardial ischemia followed by reperfusion for up to 24 hours, during which time the extent of myocardial infarction was evaluated, circulating troponin I levels were measured, and the degree of oxidative stress was evaluated. In separate studies, myocardial tissue was collected from treated and untreated mice during the early (30 minutes and 2 hours) and late (24 hours) preconditioning periods to evaluate potential cellular targets of H2S. Initial studies revealed that H2S provided profound protection against ischemic injury as evidenced by significant decreases in infarct size, circulating troponin I levels, and oxidative stress. During the early preconditioning period, H2S increased the nuclear localization of Nrf2, a transcription factor that regulates the gene expression of a number of antioxidants and increased the phosphorylation of protein kinase Cϵ and STAT-3. During the late preconditioning period, H2S increased the expression of antioxidants (heme oxygenase-1 and thioredoxin 1), increased the expression of heat shock protein 90, heat shock protein 70, Bcl-2, Bcl-xL, and cyclooxygenase-2 and also inactivated the proapoptogen Bad. Conclusions: These results reveal that the cardioprotective effects of H2S are mediated in large part by a combination of antioxidant and antiapoptotic signaling.
Balancing Margin and Mission

Competition in the nonprofit world has intensified in recent years, and nonprofit managers are challenged to devise strategies that will serve both organizational needs and public interest. We propose a framework for thinking about nonprofit competition based on the intersection of two dimensions: the domain of competition, which can be either fee-based or donative activities; and the competitive strategy, which can be either price- or differentiation-based. The experience of the American Red Cross, a prominent nonprofit organization facing competition in both fee-based and donative domains, provides data for the elaboration of the framework and for tentative conclusions about the implications of nonprofit competition for both margin and mission.
Hydrocolloids in gluten-free breads: A review

Bread is a traditional food generally prepared from wheat flour. The main wheat component responsible for bread quality is gluten, which is an essential structure-binding protein. Although important, this protein can cause health problems in predisposed individuals, and is avoided in the diet of celiac disease patients. As diagnosis methods are improved, revealing the high incidence of gluten-intolerance in the western world, the demand for novel, nutritious and high-quality gluten-free foods also ascends. However, for the production of gluten-free breads the absence of gluten is critical and challenging in regards to the bread structure. Various gluten-free formulations have applied hydrocolloids to mimic the viscoelastic properties of gluten. They comprise a number of water-soluble polysaccharides with varied chemical structures providing a range of functional properties that make them suitable to this application. This paper reviews some actual facts about celiac disease and focuses on the reported applications of hydrocolloids in gluten-free breads.
Association Between the Development of the Body Axis and the Craniofacial Skeleton Studied by Immunohistochemical Analyses Using Collagen II, Pax9, Pax1, and Noggin Antibodies

Study Design. Immunohistochemical analyses on the axial skeleton from wild type mice. Objective. In the clinic, we have previously observed cervical spine defects associated with deviations in the posterior part of the occipital bone and with morphologic and functional variations in the craniofacial skeleton. As examples, cervical spine fusions occurred frequently in patients with mandibular overjet and even more frequently and more caudally in the cervical spine in patients with sleep apnoea. The aims of the present study were to elucidate this association between the spine and the cranium by comparing gene expression domains of important developmental genes known to be involved in vertebral column formation with gene expression in the craniofacial region. Summary of Background Data. This is the first study looking specifically on gene expression in the basilar part of the occipital bone that is formed around the cranial part of the notochord, thus connecting the spine and the craniofacial skeleton. Methods. The material consisted of 4 mouse embryos p.c. day 13.5, NMRI wild-type mice, from the same litter. The body axis, the cranial base, and the craniofacial area were studied by immunohistochemical analyses using Collagen II, Pax9, Pax1, and Noggin antibodies. Results. Pax1 expression was highly similar in the posterior part of the occipital bone and in the vertebral column, indicating that the basilar part of the occipital bone from a developmental standpoint can be considered the uppermost vertebra. Pax9 and Noggin expression domains were in accordance with those described previously. Conclusion. The present study supports that the basilar part of the occipital bone may be regulated by similar developmental mechanisms as the vertebral column and may thus be regarded the uppermost vertebra. Thus, the clinically observed association between the cervical column and the craniofacial area has been proved by immunohistochemical methods.
Motion adaptive Kalman filter for super-resolution

Superresolution is a sophisticated strategy to enhance image quality of both low and high resolution video, performing tasks like artifact reduction, scaling and sharpness enhancement in one algorithm, all of them reconstructing high frequency components (above Nyquist frequency) in some way. Especially recursive superresolution algorithms can fulfill high quality aspects because they control the video output using a feed-back loop and adapt the result in the next iteration. In addition to excellent output quality, temporal recursive methods are very hardware efficient and therefore even attractive for real-time video processing. A very promising approach is the utilization of Kalman filters as proposed by Farsiu et al. Reliable motion estimation is crucial for the performance of superresolution. Therefore, robust global motion models are mainly used, but this also limits the application of superresolution algorithm. Thus, handling sequences with complex object motion is essential for a wider field of application. Hence, this paper proposes improvements by extending the Kalman filter approach using motion adaptive variance estimation and segmentation techniques. Experiments confirm the potential of our proposal for ideal and real video sequences with complex motion and further compare its performance to state-of-the-art methods like trainable filters.
A fractal model for nuclear organization: current evidence and biological implications

Chromatin is a multiscale structure on which transcription, replication, recombination and repair of the genome occur. To fully understand any of these processes at the molecular level under physiological conditions, a clear picture of the polymorphic and dynamic organization of chromatin in the eukaryotic nucleus is required. Recent studies indicate that a fractal model of chromatin architecture is consistent with both the reaction-diffusion properties of chromatin interacting proteins and with structural data on chromatin interminglement. In this study, we provide a critical overview of the experimental evidence that support a fractal organization of chromatin. On this basis, we discuss the functional implications of a fractal chromatin model for biological processes and propose future experiments to probe chromatin organization further that should allow to strongly support or invalidate the fractal hypothesis.
Psychopathology Symptoms, Rumination and Autobiographical Memory Specificity: Do Associations Hold After Bereavement?

Summary: Symptoms of psychopathology are associated with overgeneral memory retrieval. Overgeneral memory is hypothesized to be the result of an emotion regulatory process, dampening emotional reactions associated with retrieval of distressing specific memories. However, higher post-loss symptom severity has been related to higher specificity of loss-related memories recalled on the Autobiographical Memory Test. This may imply that such memories are ‘immune’ to the reduced specificity effect. We aimed to test this idea by investigating, for the first time, associations of depressive and complicated grief symptoms and depressive and grief rumination with autobiographical memory specificity on a sentence-completion task (SCEPT) in a bereaved sample. One hundred ninety-one adult mourners (89% women) filled out questionnaires and the SCEPT. A main finding was that higher depressive and complicated grief symptom and grief rumination levels were associated with reduced specificity of non-loss-related memories but not with specificity of loss-related memories. Implications of these results are discussed. Copyright © 2015 John Wiley & Sons, Ltd. Although most people adjust to the loss of a loved one without professional intervention, a minority of bereaved individuals develops mental and physical health problems and/or complications in the grieving process (Bonanno, Westphal, & Mancini, 2011; Stroebe, Schut, & Stroebe, 2007). Given this variation in outcomes, it is important to identify factors that potentially influence the way people cope with bereavement. Several authors have suggested that memory processes may play a crucial role in the development and persistence of complications in adaptation to bereavement (e.g., Boelen & van den Bout, 2008; Eisma
Saharan dust: sources and trajectories

The Sahara is the world’s largest source of aeolian desert dust, but precise information on specific sources of this material is poor and sometimes contradictory. This paper uses daily data from the Total Ozone Mapping Spectrometer (TOMS) for 1999 to identify source areas for major dust events and their trajectories of long-range transport. Two major source areas are identified: the Bodele depression and an area covering eastern Mauritania, western Mali and southern Algeria. Both of these major dust sources are primarily driven by natural factors since they are little affected by anthropogenic activities.
The Two Faces of Wisdom: Wisdom as a General Theory of Knowledge and Judgment about Excellence in Mind and Virtue vs. Wisdom as Everyday Realization in People and Products

There are several legitimate ways of conceptualizing and studying wisdom. One is largely informed by Western philosophy and treats wisdom as an analytic theory of expert knowledge, judgment, and advice about difficult and uncertain matters of life. Another is more consistent with Asian philosophical non-secularized traditions and treats wisdom as instantiated by wise persons or their products. The second approach is always but an approximation to the analytically constructed utopia of wisdom. Wise persons are approximations to wisdom, but they are not wisdom. Ardelt’s critique of our work proposes that our theoretical conception of wisdom as a body of expert knowledge in a specific subject matter is similar to ‘cold’ cognition. We disagree and assert that our conception of wisdom includes as antecedents, correlates, and consequences a rich spectrum of specific cognitive, emotional, motivational and social factors as well as life contexts. Our empirical research unequivocally supports this multidimensional and collaborative view.