Miracle-dz/UniFAR-FTUs huggingface dataset:
Cryoglobulinaemia (IgG-κ-type and IgM-γ-type) with Occluding Leukocytoclastic Vasculitis in a Patient with Vitiligo and Demyelinating Polyneuropathy.

Cryoglobulinaemia is defined as the presence of circulating immunoglobulins that precipitate with cold temperature (1, 2). Type-1 cryoglobulinaemia is induced by monoclonal immunoglobulin, whereas type-2 is induced by polyclonal IgG and monoclonal IgM and type-3 by polyclonal IgG and polyclonal IgM. Type-1 cryoglobulinaemia has no rheumatoid factor (RF) activity and usually occurs in patients with lymphoproliferative disorders. It is often associated with vascular occlusion and rarely presents as leukocytoclastic (neutrophilic small-vessel) vasculitis (3–5). Type-2 and type-3 mixed cryoglobulinaemias have RF activity and generally occur in patients with chronic infections, mostly hepatitis C virus (HCV) infection, connective tissue diseases and lymphoproliferative disorders. They are usually related to leukocytoclastic vasculitis. We report here a case of type-1 cryoglobulinaemia with leukocytoclastic vasculitis and vascular occlusion in a patient with vitiligo and chronic inflammatory demyelinating polyneuropathy (CIDP). This is the first known reported case of cryoglobulinaemia with vitiligo.
The Impact of Food Behaviour, Lifestyle and Societal Influences in the Health & Emotional Status of a Romanian High School Population

A complex social investigation of food behaviour, lifestyle and societal influences impact in the health & emotional status for a Romanian high school population of teenagers were conducted using input data from Food Behavior and Lifestyle Questionnaire (FBLQ). The impact of occidental model and media information were investigated against the traditional Romanian family model. The present study show that in condition of a good knowledge about healthy eating and no important restriction of healthy food accessibility the greatest influence in food choices, eating/lifestyle pattern were exercised by the parental family (63.3%), followed by media (29.4%) and friends (19.3%). The relevance of the traditional good family model of food choices is dominant but the eating habits (frequency of breakfast, regular meal) and lifestyle (sport, walking and smocking) are already “contaminated’ from media social models.
Studying Impacts of Personality Traits on Creativity (Case Study: University of Isfahan's Students)

This article was aimed to studying Impacts of personality Traits on creativity. In order to examining personality traits, the big five model has been used that consists of five dimensions as Extroversion, Agreeableness, Conscientiousness, Emotional stability, and Openness to experience. In order to collecting data, a questionnaire including 35 items has been designed. Statistical population is university of Isfahan’s students and sample size has been calculated 160 students that selected based on available sampling method. In order to studying impacts of personality traits on creativity the ENTER method has have been used, and Durbin-Watson test has been used to determining that whether there is self-correlation between independent variables or not. But also in order to measuring stability of questionnaires’ items, Cronbach's alpha has been calculated for each variable separately. The results of this article indicate that personality traits have effect creativity. Between five dimensions of personality, three of them have effect on creativity that including extraversion, consciousness, and emotional stability. These three dimensions have explain 43% of creativity variation. Also Durbin- Watson test results indicate that there is no
Cognitive Rehabilitation Interventions for Neglect and Related Disorders: Moving from Bench to Bedside in Stroke Patients

The spatial neglect syndrome, defined by asymmetric attention and action not attributed to primary motor or sensory dysfunction and accompanied by functional disability, is a major cause of post-stroke morbidity. In this review, we consider the challenges and obstacles facing scientific researches wishing to evaluate the mechanisms and effectiveness of rehabilitation interventions. Spatial neglect is a heterogeneous disorder, for which consensus research definitions are not currently available, and it is unclear which of the deficits associated with the syndrome causes subsequent disability. We review current opinion about methods of assessment, suggest a rational approach to selecting therapies which requires further study, and make systems-level and theoretical recommendations for building theory. We lastly review some creative questions for consideration in future research.
Prenatal exposure to maternal stress following bereavement and cardiovascular disease: A nationwide population-based and sibling-matched cohort study

Aims Cardiovascular disease (CVD) is among the leading determinants of mortality and morbidity, and causation may begin in the early intrauterine environment. Prenatal exposures to glucocorticoids or stress are potential risk factors of CVD later in life, but empirical evidence from large population studies is lacking. We explored the association between prenatal stress due to maternal bereavement following the death of a relative and CVD in the exposed offspring. Methods and results This population-based study included 2,607,851 children born in Denmark (1970–2008). Of these participants, 73,708 (2.8%) had a CVD event during follow-up (up to 40 years). A total of 50,940 (2.0%) subjects born to mothers who lost a relative during pregnancy or the year before were categorized as exposed. Cox Proportional Hazards models were used to analyse the data. The overall hazard ratio (HR) (95% confidence interval) of having a CVD was 1.13 (1.06–1.20); the estimate was 1.24 (1.11–1.38) for heart disease and 1.27 (1.01–1.60) for hypertension. Additional sibling-matched analyses showed an overall attenuated association (1.08 (0.94–1.24)). Conclusion Our results suggested a modest association between prenatal stress and CVD, both in childhood and early adulthood, which could be of importance, especially at an older age when the individuals are followed over a long period.
The effect of participating in a trauma- and stressful event-focused study.

OBJECTIVE Researchers have increasingly examined whether participants who have experienced a traumatic event should be considered vulnerable research populations. Studies have typically asked participants in trauma-focused research whether they were upset by the study or perceived any benefit from it. The current study extends such research by measuring mood and exploring potential moderators of the impact of study participation. METHOD Participants were 107 women who experienced a traumatic or stressful event and completed an event-focused research protocol. Negative affect was measured, using the Positive and Negative Affect Schedule, at the time of the study and 1 week later. RESULTS Participants reported significantly lower levels of negative affect in the week after the study than before it. Decreases in negative affect were greatest for those with highest levels of depression at the time of interview. CONCLUSIONS Participation in a trauma- or stressful-event-focused study is not harmful and may even be beneficial, especially among depressed participants.
The complexity of optimal queueing network control

We consider the classical problem of optimal control (routing and sequencing) of a network of queues. We prove that this problem is EXP-complete and, therefore, provably intractable. Similar results are established for restricted versions of the problem. A weaker result is also established for the restless bandit problem. <<ETX>>
Wave refocusing for linear diffractor using the time‐reversal principle

One of the problems encountered in a variety of near‐surface investigations is detecting and mapping localized heterogeneities. The heterogeneities may be classified under two kinds of objects: (1) a point diffractor that can be considered as an approximation of a small quasi‐isometric, such as small karstic cavities and caves; (2) a linear diffractor roughly approximating an elongated object, such as a tube or fault plane. The point and linear diffractors generate two types of seismic diffraction: tip and edge waves, respectively. During the last few decades, different methods were proposed by many researchers for detecting these heterogeneities utilizing seismic waves diffracted by them. An alternative method for detecting point diffractors using a time‐reversal principle combined with focusing analysis is proposed in this study: we present an extension of the time‐reversal method for linear diffractors. It consists of a coherent summation of seismic energy along edge‐diffraction traveltimes. Real data examples show the feasibility and efficiency of the proposed method.
The Case for Teaching Social Skills in the Classroom: A Review

Schools traditionally have viewed the process of equipping students with the necessary academic skills, i.e., reading, writing and arithmetic, as being their primary, and in some cases, sole function. Although considered to be a major socializing institution, and as such the purveyor of not only academic skills but social behaviors and attitudes as well, schools have historically placed little emphasis upon formal social skill instruction. It appears, however, that the development of certain prerequisite social skills may be crucial to the academic instructional experience as well as the overall school success of the individual student. The concept of "social skill" has been defined by Libet and Lewinsohn (1973) as the ability to emit behaviors that are positively or negatively reinforced and not to emit behaviors that are punished or extinguished by others. Taking a similar position, MacDonald and Cohen (Note 1) describe a social skills training program as requiring participants to: "(1) perform those behaviors evaluated as prosocial, (2) refrain from performing those behaviors not evaluated as prosocial, and (3) reinforce
The Effects of Nonpromotion on Elementary and Junior High School Pupils: A Meta-Analysis

In this study data from all studies identified as meeting the selection criteria were mathematically integrated to determine the effect of grade-level retention on elementary and/or junior high school pupils. When each effect size calculated was treated equally, a grand mean effect size of −. 37 was obtained indicating that, on the average, promoted children scored . 37 standard deviation units higher than retained children on the various outcome measures. When the effect sizes within each study were first averaged so that each study could be given equal weight, a grand mean of −. 34 was obtained. By using the effect sizes from only those studies in which the promoted and nonpromoted pupils had been matched, a grand mean of −. 38 was calculated. The high degree of consistency in these measures lends credibility to the validity of these findings. In addition to the grand means, effects sizes were calculated on various dependent variable measures, including academic achievement (further subdivided into various areas), personal adjustment (which included self-concept, social adjustment, and emotional adjustment), and attitude toward school, behavior, and attendance. In all cases, the outcomes for promoted pupils were more positive than for retained pupils.
Toward authenticated caller ID transmission: The need for a standardized authentication scheme in Q.731.3 calling line identification presentation

The rising prevalence of phone fraud is hurting consumers and businesses. With about a half million reports each year in the United States, phone fraud complaints have more than doubled since 2013. In the current calling line identification presentation scheme, the caller ID is trivially spoofed. Scammers are using spoofed caller IDs to trick their victims into answering unwanted calls and further a variety of scams. To provide a solution to this problem, this paper proposes an authentication scheme that provides the possibility of a security indicator for the current Q.731. 3 calling line identification presentation supplementary service. The goal of this proposal is to help prevent users from falling victim to phone impersonation scams, as well as provide a foundation for future defenses to stop unwanted calls based on the caller ID information. This work will help to guide the future development of a standardized scheme in authenticating SS7 identities.
Role of capsule endoscopy in suspected celiac disease: A European multi-centre study

AIM To analyze the diagnostic yield (DY), therapeutic impact (TI) and safety of capsule endoscopy (CE). METHODS This is a multi-centre, observational, analytical, retrospective study. A total of 163 patients with suspicion of celiac disease (CD) (mean age = 46.4 ± 17.3 years, 68.1% women) who underwent CE from 2003 to 2015 were included. Patients were divided into four groups: seronegative CD with atrophy (Group-I, n = 19), seropositive CD without atrophy (Group-II, n = 39), contraindication to gastroscopy (Group-III, n = 6), seronegative CD without atrophy, but with a compatible context (Group-IV, n = 99). DY, TI and the safety of CE were analysed. RESULTS The overall DY was 54% and the final diagnosis was villous atrophy (n = 65, 39.9%), complicated CD (n = 12, 7.4%) and other enteropathies (n = 11, 6.8%; 8 Crohn’s). DY for groups I to IV was 73.7%, 69.2%, 50% and 44.4%, respectively. Atrophy was located in duodenum in 24 cases (36.9%), diffuse in 19 (29.2%), jejunal in 11 (16.9%), and patchy in 10 cases (15.4%). Factors associated with a greater DY were positive serology (68.3% vs 49.2%, P = 0.034) and older age (P = 0.008). On the other hand, neither sex nor clinical presentation, family background, positive histology or HLA status were associated with DY. CE results changed the therapeutic approach in 71.8% of the cases. Atrophy was associated with a greater TI (92.3% vs 45.3%, P < 0.001) and 81.9% of the patients responded to diet. There was one case of capsule retention (0.6%). Agreement between CE findings and subsequent histology was 100% for diagnosing normal/other conditions, 70% for suspected CD and 50% for complicated CD. CONCLUSION CE has a high DY in cases of suspicion of CD and it leads to changes in the clinical course of the disease. CE is safe procedure with a high degree of concordance with histology and it helps in the differential diagnosis of CD.
Endothelin-1 Release during the Early Phase of Reperfusion Is a Mediator of Myocardial Reperfusion Injury

Purpose: In acute myocardial infarction, left ventricular (LV) unloading reduces endothelin-1 (ET-1) release. We tested that endogenous ET-1 released during acute myocardial infarction might mediate ischemia/reperfusion (I/R) injury by stimulating increased intracellular calcium concentration, [Ca2+]i, and apoptosis. Methods: Rabbits were subjected to 1 h of coronary artery occlusion followed by 3 h of reperfusion. Unloading was initiated 15 min prior to reperfusion and was maintained during reperfusion. The control group was subjected to reperfusion. Animals were treated with ET-1 receptor antagonist BQ123. In parallel, isolated rabbit cardiomyocytes subjected to simulated I/R with or without ET-1 or BQ123, intracellular Ca2+ and cell death were assessed with flow cytometry. Results: LV unloading prior to reperfusion reduced myocardial ET-1 release at 2 h of reperfusion. Infarct size was reduced in unloaded and BQ123 groups versus controls. LV unloading and BQ123 treatment reduced the percentage of apoptotic cells associated with increases in Bcl-2 protein levels in ischemic regions. BQ123 reduced both ET-1-induced [Ca2+]i increase and cell death for myocytes subjected to stimulated I/R. Conclusion: We propose that components of reperfusion injury involve ET-1 release which stimulates calcium overload and apoptosis. Intravenous ET-1 receptor blockade prior to reperfusion may be a protective adjunct to reperfusion therapy in acute myocardial infarction patients.
Effectiveness of Metacognitive Therapy in Reducing psychological and MetaCognitive factors in Patients with Major Depressive Disorder in a Military Hospital

Purpose: To investigate the effectiveness of metacognitive therapy in patients with major depressive disorder. The population of this study included all patients admitted to the Army Hospital No. 520 diagnosed with major depressive disorder from which 30 individuals were selected by using random sampling into experimental and control groups (n = 15 experimental and n = 15 control). Materials and Methods: The research method was a quasi-experimental design in which pretest andpost-test with control group design was used. The instrument consists of metacognitive therapy, Beck Depression Inventory (BDI-II) and the Metacognition Questionnaire (MCQ-30). Data were analyzed with inferential statistics methods including t-test for independent groups and analysis of covariance. Results: Results in this study showed that meta-cognitive therapy reduces emotional symptoms (sadness, frustration, guilt, self-loathing, crying, restlessness, social withdrawal and irritability), cognitive symptoms (pessimism, expectation of failure, feeling of punishment, self-accusation, suicidal thoughts, indecisiveness, worthlessness, and difficulty in concentration), physical symptoms (disability, change in sleep patterns, fatigue, change in appetite and sexual interest) and metacognitive beliefs. Conclusion: This study showed that metacognitive therapy is an effective method in reducing symptoms of major depressive disorder and should be considered within the treatment of the aforementioned disorder.
The Effects of the Sarbanes-Oxley Act of 2002 on Earnings Quality

The Sarbanes-Oxley Act of 2002 (SOX) was enacted into law on July 30, 2002 after the collapse of WorldCom and Enron. SOX is designed to enhance the reliability and accuracy of the financial statements by placing more responsibility on the management of publicly traded companies. It is believed that under SOX public companies will have less opportunity to manage their earnings and commit fraud. In addition, SOX places further responsibilities on audit firms while strengthening their independence. The purpose of this study is to empirically examine within the S&P 500 (1) whether SOX has improved the quality of the earnings reported in the financial statements and (2) investigate associations of firm specific characteristics with earnings quality changes surrounding SOX. The results indicate that management reports higher quality earnings after SOX, and the change is negatively associated with cumulative abnormal stock returns during the SOX legislative period and positively associated with changes in size. * Corresponding author.
Congenital long QT syndrome.

C long QT syndrome (LQTS) is a rare heterogeneous disorder with multiple ion channel defects primarily affecting cardiac potassium, sodium, and calcium channels. These ion channel defects produce abnormally prolonged ventricular repolarization resulting in a long QT interval on electrocardiogram. This delay in repolarization predisposes patients to syncope, ventricular arrhythmias, and sudden cardiac death. The typical ECG features of congenital LQTS are QT interval prolongation and abnormalities of the T-wave morphology. Diagnosis of this condition relies heavily on serial ECG analysis, exercise treadmill testing, holter monitoring, and genetic testing. Due to the variation in symptoms and ECG findings, presentation and diagnosis of congenital LQTS can occur in the newborn period up through adulthood. To date, there have been 12 genes identified as causative for congenital LQTS, with the most common being LQT1, LQT2, and LQT3. These mutations account for most cases of congenital LQTS, with an estimated prevalence of 45%, 45%, and 7%, respectively. This article briefly discusses the 3 most common forms of congenital LQTS and reviews their common ECG findings.
Novel defense mechanism against data flooding attacks in wireless ad hoc networks

Mobile users like to use their own consumer electronic devices anywhere and at anytime to access multimedia data. Hence, we expect that wireless ad hoc networks will be widely used in the near future since these networks form the topology with low cost on the fly. However, consumer electronic devices generally operate on limited battery power and therefore are vulnerable to security threats like data flooding attacks. The data flooding attack causes Denial of Service (DoS) attacks by flooding many data packets. However, there are a few existing defense systems against data flooding attacks. Moreover, the existing schemes may not guarantee the Quality of Service (QoS) of burst traffic since multimedia data are usually burst. Therefore, we propose a novel defense mechanism against data flooding attacks with the aim of enhancing the throughput. The simulation results show that the proposed scheme enhances the throughput of burst traffic.
A general test to check the feasibility of linear interference alignment

In this paper, we propose a test for checking the feasibility of linear interference alignment (IA) for multiple-input multiple-output (MIMO) channels with constant coefficients for any number of users, antennas and streams per user. We consider the compact complex manifold formed by those channels, pre-coders and decoders that satisfy the polynomial IA equations (the so-called solution variety), and study its projection onto the input space formed by the interference channels. When the derivative of this projection is surjective, namely when the tangent space of the solution variety is projected into the whole tangent space of the inputs space, the linear alignment problem is feasible; otherwise is infeasible. Building on these results, a general feasibility test, which amounts to check whether a given matrix is full-rank or not, is proposed.
Item-Based Psychometrics of the Preschool Behavioral and Emotional Rating Scale

The Preschool Behavioral and Emotional Rating Scale (PreBERS) is an assessment of emotional and behavioral strengths in preschoolers with well-established reliability and validity for educational and clinical application in children with and without disabilities. The present study provides further evidence of psychometric rigor for items and subscales within the PreBERS, including internal consistency, reliability, item quality, and factorial validity. A national sample of 1,292 preschool children whose teachers scored the PreBERS were analyzed using classical test theory, Rasch modeling, and confirmatory factor analysis. Results confirmed that individual items were internally consistent within a four-factor model, and showed consistent item difficulty, discrimination, and fit relative to their respective subscale scores. This analysis provides further confidence for the use of the PreBERS by teachers to determine emotional and behavioral strengths in preschool children.