Miracle-dz/UniFAR-FTUs huggingface dataset:
Heartfelt empathy? No association between interoceptive awareness, questionnaire measures of empathy, reading the mind in the eyes task or the director task

Interoception, defined as afferent information arising from within the body, is the basis of all emotional experience and underpins the ‘self. ’ However, people vary in the extent to which interoceptive signals reach awareness. This trait modulates both their experience of emotion and their ability to distinguish ‘self’ from ‘other’ in multisensory contexts. The experience of emotion and the degree of self/other distinction or overlap are similarly fundamental to empathy, which is an umbrella term comprising affect sharing, empathic concern and perspective-taking (PT). A link has therefore often been assumed between interoceptive awareness (IA) and empathy despite a lack of clear evidence. To test the hypothesis that individual differences in both traits should correlate, we measured IA in four experiments, using a well-validated heartbeat perception task, and compared this with scores on several tests that relate to various aspects of empathy. We firstly measured scores on the Index of Interpersonal Reactivity and secondly on the Questionnaire of Cognitive and Affective Empathy. Thirdly, because the ‘simulationist’ account assumes that affect sharing is involved in recognizing emotion, we employed the ‘Reading the Mind in the Eyes Task’ for the recognition of facial expressions. Contrary to expectation, we found no significant relationships between IA and any aspect of these measures. This striking lack of direct links has important consequences for hypotheses about the extent to which empathy is necessarily embodied. Finally, to assess cognitive PT ability, which specifically requires self/other distinction, we used the ‘Director Task’ but found no relationship. We conclude that the abilities that make up empathy are potentially related to IA in a variety of conflicting ways, such that a direct association between IA and various components of empathy has yet to be established.
Efficient Support Counting of Candidate Itemsets for Association Rule Mining

Association rule mining has gathered great attention in recent years due to many important applications. Some influential algorithms have been developed in two categories: (1) candidate-generation-and-test approach such as Apriori [3], (2) patterngrowth approach such as FP-growth [5]. They all suffer from the problem of multiple database scans and setting minimum support thresholds to prune infrequent candidates for process efficiency. We propose a new approach, Fast Support Enumeration (FSE), to mining association rules without the need of predetermining the minimum support threshold. The FSE scans the transaction database only once and enumerates all candidate itemsets with efficient indexing of their support counters that can produce meaningful rules very easily for any item appears at least once in the transactions.
A high voltage gain quasi Z-source isolated DC/DC converter

A compact quasi-Z-source DC/DC converter is presented with high voltage gain, isolated output, and improved efficiency. The improvements in size and performance were achieved by using a square wave inverter with only two output switches driving an isolating transformer in push-pull mode, followed by a voltage doubling output rectifier. The converter is well-suited to applications requiring a high voltage gain, especially renewable energy sources such as photovoltaic and fuel-cell power supplies. To demonstrate the converter's performance a prototype designed to output 400 V at 500 W was constructed and tested. The efficiency at full load varied from 89.0% to 97.4% as the input voltage changed from 44 V to 82 V.
E-Service Quality : Pembentuk Loyalitas Dalam Pembelian Online

Tujuan dari penelitian ini adalah untuk menganalisis variabel-variabel yang mempengaruhi tingkat loyalitas konsumen dalam pembelian online. Variabel-variabel tersebut diantaranya e-service quality, nilai yang dirasakan konsumen (perceived value), dan kepuasan konsumen. Penelitian ini dilakukan pada individu yang sudah atau pernah melakukan pembelian secara online melalui Zalora.co.id dan berniat untuk loyal, dengan menggunakan teknik convenience sampling. Sampel yang diambil berjumlah 150 responden, dilakukan dengan menyebarkan kuesioner. Pengujian hipotesis dilakukan dengan analisis SEM dengan bantuan Generalized Structured Component Analysis (GeSCA). Hasil penelitian menyimpulkan bahwa (1) e-service quality berpengaruh signifikan pada loyalitas konsumen (2) e-service quality berpengaruh signifikan pada kepuasan konsumen (3) e-service quality berpengaruh signikan pada nilai yang dirasakan konsumen (4) nilai yang dirasakan konsumen berpengaruh signifikan pada kepuasan konsumen (5) nilai yang dirasakan konsumen tidak berpengaruh pada loyalitas konsumen (6) kepuasan konsumen berpengaruh signifikan pada loyalitas konsumen. Hasil penelitian dapat digunakan sebagai acuan bagi praktisi untuk mengambil langkah dalam menentukan strategi pemasaran melalui pembelian online.
Development of a nutrient‐dense complementary food using amaranth‐sorghum grains

Abstract Thin porridge from cereals and starchy tubers is a common complementary food in Sub Saharan Africa. It may be high in antinutrients, low in energy, and nutrient density hence inadequate in providing infants' high energy and nutrients requirements per unit body weight. Consequently, undernourishment levels among children under 5 years are high. Therefore, there is need to avail nutrient‐dense complementary foods especially for children in low‐resource settings. The study was aimed at developing a nutrient‐dense complementary food from amaranth and sorghum grains. Amaranth grain, a pseudocereal, though rarely used as a complementary food in Kenya has a higher nutritional quality than other staples. Plant‐based foods are known to have high levels of antinutrients. Steeping and germination were used to reduce the levels of antinutrients and enhance the bioavailability of minerals in the grains. Various steeped and germinated amaranth and sorghum grains formulations were made to find the ratio with the highest nutrient content and lowest antinutrient levels. The 90% amaranth‐sorghum grains formulation had significantly (F = 32.133, P < 0.05) higher energy (5 kcal per g on dry weight basis) than the other formulations and a protein content of 14.4%. This is higher than the estimated protein needs from complementary foods even for a 12–23 months child of low breast milk intake (9.1 g/d). Antinutrients could not be detected which could imply enhanced nutrient bioavailability. Therefore, a nutrient‐dense complementary food product was developed from steeped and germinated amaranth and sorghum grains with 90% amaranth grain. In ready to eat form, it would give an energy content of 1.7 kcal per g (dilution of 1:2 amaranth‐sorghum flour to water) and 1.2 kcal per g (dilution of 1:4 amaranth‐sorghum flour to water). It can be used as a nutrient‐dense complementary food and for other vulnerable groups.
Galectin-3 and Its Genetic Variation rs4644 Modulate Enterovirus 71 Infection

Galectin-3, a chimeric type β-galactoside-binding protein, is known to modulate viral infection; however, its role in enterovirus 71 (EV71) infection has not been investigated. We generated galectin-3 null rhabdomyosarcoma (RD) cells and evaluated whether EV71 infection would be affected. In galectin-3 null cells, the released and intracellular EV71 viral loads were suppressed after 24 h of infection, and cell death rates were significantly lower, while cell proliferation remained unaltered. In addition, RD cells expressing a nonsynonymous genetic variant of galectin-3, rs4644 (LGALS3 +191C/A, P64H), produced lower virus titers than those with wild-type galectin-3 (C allele). To clarify whether the in vitro viral load reduction correlates with clinical severity, we enrolled children with laboratory-confirmed EV71 infection. Since hyperglycemia is an indicator of severe EV71 infection in children, 152 of 401 enrolled children had glucose examinations at admission, and 59 subjects had serum glucose levels ≥ 150 mg/dL. In comparison to the rs4644 AA genotype (2.2 ± 0.06 log10 mg/dL), serum glucose levels during EV71 infection were higher in patients with CC (2.4 ± 0.17 log10 mg/dL, p = 0.03) and CA (2.4 ± 0.15 log10 mg/dL, p = 0.02) genotypes, respectively. These findings suggest that the rs4644 AA genotype of galectin-3 might exert a protective effect. In summary, galectin-3 affects EV71 replication in our cellular model and its variant, rs4644, is associated with hyperglycemia in the clinical setting. The underlying mechanism and its potential therapeutic application warrant further investigation.
Detection of connecting points in Thai printed characters by combining inductive logic programming with backpropagation neural network

The paper presents a method for detecting the connecting points in connected Thai printed characters. In Thai optical character recognition systems, an important problem that decreases the accuracy occurs due to connected characters. These characters could cause errors in the segmentation process. To attack this problem, we first extract the features of the connecting points in the character images. Then, we employ inductive logic programming to produce the rules that are used to classify the unseen images. Finally, we use a backpropagation neural network to make these rules more flexible. The experimental results show that our method achieves 94.94% accuracy.
Protein secretion systems in Mycobacteria

Mycobacteria have a unique cell‐envelope structure which protects the bacteria from the extracellular environment by limiting access to noxious molecules from the outside. This extremely hydrophobic and thick barrier also poses a unique problem for the export of bacterial products. Here we review the multiple protein secretion pathways in Mycobacteria, including the general secretion pathway and the Twin‐Arginine Transporter, with an emphasis on the ESX‐1 alternate secretion system. This newly identified protein secretion system is required for growth during infection and has provided insight into how M. tuberculosis manipulates the host immune response during infection.
Glucose and lactate kinetics in the neonate.

To evaluate the ontogeny of neonatal glucose homeostasis, glucose production and lactate production have been measured in nine prematurely born appropriate for gestational age neonates [birth weight 1985 +/- 100 g, (SEM) gestational age 33.6 +/- 0.7 weeks] and five full term appropriate for gestational age neonates [birth weight 3254 +/- 111 g, gestational age 40.8 +/- 0.4 wks] and compared to six non pregnant, nondiabetic adults [weight of 57.7 +/- 2.2 kg, age 32 +/- 2 years]. Ra glucose (preterm) averaged 27.7 +/- 2.8 mumol.kg-1 min-1 (5.0 +/- 0.5 mg.kg-1 min-1) and Ra glucose (term) averaged 28.9 +/- 3.9 mumol.kg-1 min-1 (5.2 +/- 0.7 mg.kg-1 min-1); both were higher than the Ra glucose of the adult controls (16.1 +/- 2.8 mumol.kg-1 min-1 (2.9 +/- 0.5 mg.kg-1 min-1) (P less than 0.05 vs preterm and P less than 0.05 vs. term). Ra lactate (preterm) averaged 100 +/- 11.9 mumol.kg-1 min-1 (9.1 +/- 1.1 mg.kg-1 min-1) and Ra lactate (term) average 77.2 +/- 13.0 mumol.kg-1 min-1 (7.1 +/- 1.2 mg.kg-1 min-1); both were higher than the Ra lactate of the adult controls 35.9 +/- 6.5 mumol.kg-1 min-1 (3.3 +/- 0.6 mg.kg-1 min-1) (P less than 0.01 vs preterm and P less than 0.05 vs. term). The potential for gluconeogenesis from lactate was estimated by determining the ratio of [Ra Lactate/Ra Glucose]. The [Ra Lactate/Ra Glucose] (preterm) (187 +/- 12 (x10(-2)) was similar to that of the [Ra Lactate/Ra Glucose] (term) (136 +/- 16) (x10(-2)). (ABSTRACT TRUNCATED AT 250 WORDS)
Gymnastic Wrist Injuries

During gymnastic activities, the wrist is exposed to many different types of stresses, including repetitive motion, high impact loading, axial compression, torsional forces, and distraction in varying degrees of ulnar or radial deviation and hyperextension. Many of these stresses are increased during upper extremity weight-bearing and predispose the wrist to high rates of injury during gymnastics. Distal radius stress injuries are the most common and most documented gymnastic wrist conditions. Other conditions include scaphoid impaction syndrome, dorsal impingement, scaphoid fractures, scaphoid stress reactions/fractures, capitate avascular necrosis, ganglia, carpal instability, triangular fibrocartilage complex tears, ulnar impaction syndrome, and lunotriquetral impingement. It is important to diagnose quickly and accurately the specific injury to initiate expediently the proper treatment and limit the extent of injury. In addition, a gymnast's training regimen should also include elements of injury prevention.
Molecular Pathogenesis and Targeted Therapies in Well-Differentiated Thyroid Carcinoma

Four proto-oncogenes commonly associated with well-differentiated thyroid carcinoma, rearranged during transfection (RET)/papillary thyroid cancer, BRAF, RAS, and PAX8/peroxisome proliferator activated receptor-γ, may carry diagnostic and prognostic significance. These oncogenes can be used to improve the diagnosis and management of well-differentiated thyroid carcinoma. Limited therapeutic options are available for patients with metastatic well-differentiated thyroid cancer, necessitating the development of novel therapies. Vascular endothelial growth factor (VEGF)- and RET-directed therapies such as sorafenib, motesanib, and sunitinib have been shown to be the most effective at inducing clinical responses and stabilizing the disease process. Further clinical trials of these therapeutic agents may soon change the management of thyroid cancer.
[Mortality of patients who are older than 75 years after ST elevation myocardial infarction in clinical practice].

BACKGROUND Patients who are older than 75 years are often excluded in clinical trials evaluating therapies for ST elevation myocardial infarction. Therefore there is a lack of prospective data for this steadily increasing number of elderly patients. PATIENTS AND METHODS Between 07/2000 and 11/2002 a total of 16 823 patients with acute coronary syndromes in 154 hospitals were enrolled in the ACOS registry, with 8309 having a STEMI. Baseline characteristics, therapies during the hospital course and at discharge, hospital-mortality and 1-year mortality were prospectively collected. In this study we analysed the outcome of patients older than 75 years with STEMI of less than 24 duration. RESULTS A total of 2045 patients > 75 years (median age 80.1 years, 53.9 % women) were included. Of the latter 51 % were treated conservatively, 19 % with fibrinolysis and 30 % with primary PCI. In-hospital mortality in the three groups was 23.4 %, 25.4 % und 10.2 %, while total mortality after one year was 52.4 %, 41.3 % und 19.3 %, respectively. In the multivariate analysis both primary PCI (odds ratio 0.36, 95 % CI 0.25 - 0.52) and fibrinolysis (odds ratio 0.65, 95 % CI 0.44 - 0.97) where associated with a lower mortality after discharge. CONCLUSION Hospital- as well as 1-year mortality in patients with STEMI who are older than 75 years are high. Primary PCI is associated with a decrease of in-hospital and 1-year mortality, while fibrinolysis improves mortality after discharge. Therefore early reperfusion therapy, preferably with primary PCI should be considered in elderly patients, after taking in count biological age and major comorbidities.
A 1.22 TOPS and 1.52 mW/MHz Augmented Reality Multicore Processor With Neural Network NoC for HMD Applications

Real-time augmented reality (AR) is actively studied for the future user interface and experience in high-performance head-mounted display (HMD) systems. The small battery size and limited computing power of the current HMD, however, fail to implement the real-time markerless AR in the HMD. In this paper, we propose a real-time and low-power AR processor for advanced 3D-AR HMD applications. For the high throughput, the processor adopts task-level pipelined SIMD-PE clusters and a congestion-aware network-on-chip (NoC). Both of these two features exploit the high data-level parallelism (DLP) and task-level parallelism (TLP) with the pipelined multicore architecture. For the low power consumption, it employs a vocabulary forest accelerator and a mixed-mode support vector machine (SVM)-based DVFS control to reduce unnecessary external memory accesses and core activation. The proposed 4 mm × 8 mm HMD AR processor is fabricated using 65 nm CMOS technology for a battery-powered HMD platform with real-time AR operation. It consumes 381 mW average power and 778 mW peak power at 250 MHz operating frequency and 1.2 V supply voltage. It achieves 1.22 TOPS peak performance and 1.57 TOPS/W energy efficiency, which are, respectively, 3.58 × and 1.18 × higher than the state of the art.
The doripenem serum concentrations in intensive care patients suffering from acute kidney injury, sepsis, and multi organ dysfunction syndrome undergoing continuous renal replacement therapy slow low-efficiency dialysis

Doripenem is a novel wide-spectrum antibiotic, and a derivate of carbapenems. It is an ideal antibiotic for treatment of serious nosocomial infections and severe sepsis for its exceptionally high efficiency and broad antibacterial spectrum of action. Doripenem is eliminated mainly by the kidneys. In cases of acute kidney injury, dosing of doripenem depends on creatinine clearance and requires adjustments. Doripenem is eliminated during hemodialysis because its molecular weight is 300–400 Da. The aim of this study was to establish the impact of continuous renal replacement therapy (CRRT) slow low-efficiency dialysis (SLED) on doripenem serum concentrations in a population of intensive-therapy patients with life-threatening infections and severe sepsis. Ten patients were enrolled in this observational study. Twelve blood samples were collected during the first administration of doripenem in a 1-hour continuous infusion while CRRT SLED was provided. Fluid chromatography was used for measurement of the concentration of doripenem in serum. In all collected samples, concentration of doripenem was above the minimum inhibition concentration of this antibiotic. Based on these results, we can draw the conclusion that doripenem concentration is above the minimum inhibition concentration throughout all of CRRT. The dosing pattern proposed by the manufacturer can be used in patients receiving CRRT SLED without necessary modifications.
Age, Gender and Communication Networks

In this paper, we address some sociological and topological issues associated with mobile phone communication. Based on a dataset of a few million users, we use customers' age and gender information to study relation between these parameters and the average behavior of users in terms of number of calls, number of SMS and calls duration. We also study the dataset from a networking point of view: we define different profiles based on the topological properties of the personal network of each individual and study the relations between these profiles and the age of customers.
Notes on Maxwell & Delaney 11 Single-factor Within-subject Designs

The ideas of blocking and the analysis of covariance were discussed in chapter 9. By explicitly incorporating individual differences among subjects into the design and analysis of experiments, blocking and ancova can significantly reduce error variance and, consequently, increase the power of our statistical tests. One can think of within-subjects designs as the ultimate extension of the blocking approach: each block consists of a single subject. If certain assumptions are met, this type of design can significantly increase the sensitivity of an experiment. Up to now we have discussed experimental designs in which different treatments have been administered to different groups of subjects. Such designs are called between-subjects designs. In a within-subject design, each subject receives all treatments. This type of design is sometimes referred to as a repeated-measures design, because multiple measures are obtained on each subject. However, some statisticians prefer to use repeated-measures to refer only to designs in which the same dependent measure is taken at multiple times. There are, of course, a wide range of within-subjects experimental designs. I will focus on designs in which the multiple measures obtained from each subject are all of the same type. I will not address designs that obtain measures that differ qualitatively. For example, we could imagine a situation where each subject provides dependent measures of response time and response accuracy in a visual detection task. Such data should be analyzed using a multivariate approach described in chapters 13 and 14 in your textbook, and will not be considered here. The basic approach we will take to analyze within-subject data is to treat subjects as an experimental factor. However, there are several aspects of within-subjects designs that make the analysis more difficult. The first is that, in most within-subject designs, there is only one observation per cell (i.e., subject-treatment combination). That is to say, each subject is tested once, and only once, in each experimental condition. This means that we cannot measure " within-cell " error as we did in factorial experiments. The second distinguishing characteristic of this design is that the subjects factor is a random factor. Most experimental treatments are fixed factors: if the experiment was repeated, we would use the same levels on the experimental variables. Subjects, however, is a random factor: If the experiment was repeated, we would use different " levels " on the subjects factor (i.e., we 1
Two separate Ni2+-sensitive voltage-gated Ca2+channels modulate transretinal signalling in the isolated murine retina

Purpose: Light‐evoked responses from vertebrate retinas were recorded as an electroretinogram (ERG). The b‐wave is the most prominent component of the ERG, and in the bovine retina its NiCl2‐sensitive component was attributed to reciprocal signalling by pharmacoresistant R‐type voltage‐gated Ca2+ channels, which similar to other voltage‐dependent Ca2+ channels trigger and control neurotransmitter release. The murine retina has the great advantage that the effect of gene inactivation for Ni2+‐sensitive Ca2+ channels can be analysed to prove or disprove that any of these Ca2+ channels is involved in retinal signalling.
A Neural Circuit Model of the Ventral Cochlear Nucleus

We present a detailed network model of neurons of the cochlear nucleus to explore leveldependent processing by T stellate cells. These cells selectively process input from two types of auditory nerve fibres to enhance their dynamic range. We use a biologically plausible network between T stellate, D stellate and tuberculoventral cells, to show how level-dependent selective processing can be used to recreate rate-level curves seen in vivoand encode the spectrum of the vowel /ε/. The compartmental models include recently formulated current models of ventral cochlear nucleus cells to give greater accuracy of cell spiking behaviour.