Miracle-dz/UniFAR-FTUs huggingface dataset:
ANALISIS SWOT SEBAGAI UPAYA PENINGKATAN KINERJA PENGAWASAN APARAT INSPEKTORAT PROVINSI JAWA TENGAH

Penelitian ini berusaha menyediakan peta keuntungan, kerugian, tantangan dan kesempatan yang berkaitan dengan kinerja inspektorat (Supervisory Board). Hasil dari penelitian ini adalah bahwa untuk meningkatkan kinerjanya, Inspectorat (Supervisory Board) bisa menerapkan 4 strategi yang tesedia pada matriks SWOT. Inspektorat (Supervisory Board) sebaiknya bisa mengatur kekuatan dan meminimalkan kelemahan yang dimiliki, memanfaatkan kesempatan yang berhubungan de-ngan tantangan dalam bentuk sumber daya manusia, anggaran, teknologi informasi dan struktur organisasi yang tepat. This study attempts to provide mapping of the advantages, disadvantages, challenges, and opportunities associated with the performance of the Inspectorate (Supervisory Board). The results indicate that for improving the performance, the Inspectorate (Supervisory Board) of Central Java Province can apply one of the four strategies that are available on TOWS matrix above. The four strategies that can be selected are SO Strategy (Strengths-Opportunities), WO Strategy (Weakness-Opportunities), ST Strategy (Strengths-Threats), and WT Strategy (Weakness-Threats). It is suggested that for improving its performance, the Inspectorate (Supervisory Board) should be able to maintain power and minimize the weaknesses possessed; exploit opportunities and deal with the existing challenges in the form of HR, Budget, Information Technology, and proper Organizational Structure.
What Are the Benefits of Hosting a Major League Sports Franchise

Over the last few decades the number of U.S. metropolitan areas large enough to host a franchise from one of the four major professional sports leagues has soared. Even as major league baseball, football, basketball and hockey have expanded to include more franchises, demand by metro areas continues to exceed supply. Metro areas have thus been forced to compete with each other to retain and attract franchises. ; The resulting large public spending on new sports facilities has been quite controversial. Usually these costly projects are justified by claims that hosting a sports franchise spurs local economic development by creating numerous new jobs and boosting local tax revenue. Independent economic studies suggest, however, that such benefits are much smaller than the outlay of public funds. ; Does this mean that public funding of sports franchises is not justified? Perhaps not. Rappaport and Wilkerson review the current rush by metro areas to build sports facilities. They lay out the arguments both in favor of and against using public funds to do so. They show why the job creation and tax revenue benefits from hosting a major league franchise fall far short of typical public outlays on constructing a new sports facility. Finally, they argue that the large quality-of-life benefits associated with hosting a major league team may justify the public outlays.
Proteomic analysis of Epstein‐Barr virus‐transformed human B‐lymphoblastiod cell lines before and after immortalization

Infection of human B lymphocytes with Epstein‐Barr virus (EBV) induces proliferative B‐lymphoblastoid cell lines (LCLs). However, the majority of EBV‐transformed LCLs are mortal and unable to avoid cellular senescence. In our previous experiment, three immortalized LCLs were established by passages of EBV‐transformed LCLs for nearly five years accompanied by strong telomerase activity. In the present study, proteomic profiles of these three LCLs were analyzed comparatively at the early and the late passages of cell culture, and a protein spot was found which most significantly decreased with the immortalization in two LCLs. The expression of the protein in the third LCL was suppressed at 17 population doubling level (PDL), already suggesting that part of the immortalization process had been initiated before 17 PDL. The protein was assigned to ssp7001 (16.3 kDa, pI 6.0) by referring to our TMIG‐2DPAGE proteome database. The protein was transferred onto a polyvinylidene difluoride (PVDF) membrane and digested with lysilendopeptidase to perform peptide mass fingerprinting by nanoelectrospray ionization mass spectrometry (nano‐ESI‐MS). Subsequent MS‐Fit database search indicated that ssp7001 is a phosphoprotein stathmin. This speculation was confirmed by the tandem MS (MS/MS) analysis in a Q‐Tof system and by Edman degradation microsequencing.
Fiscal Reliance on Tariff Revenues: In Search of a Political Economy Explanation?

One “stylized fact” about trade policy is that trade taxes as a proportion of total tax revenue are inversely related to a country's economic development, as in countries with poor administrative capabilities trade taxes represent the easiest way for governments to raise revenue (Administrative Capabilities Hypothesis). In this paper we develop an alternative explanation based on political economy considerations: using data from 64 developing countries from 1982 until 1997 we find that the Administrative Capabilities Hypothesis must be complemented with a political economy explanation in order to be able to provide a better account of the relevant empirical evidence.
Dengue virus infection induces chromatin remodeling at locus AAEL006536 in the midgut of Aedes aegypti.

OBJECTIVE To identify and characterize Aedes aegypti's AAEL006536 gene proximal upstream cis-regulatory sequences activated by dengue virus infection. MATERIALS AND METHODS A. aegypti Rockefeller strain mosquitoes were blood fed or infected with dengue virus 2. Open chromatinprofiling was then carried out in pools of midguts from each group of mosquitoes. RESULTS The proximal upstream region does not contain open chromatin sites in the midguts of blood-fed mosquitoes as detected by FAIRE-qPCR. In contrast, two cis-regulatory sites were identified in the same upstream region of dengue virus-infected mosquito midguts. The distal sequence contains STAT-, REL- and C/EBP-type transcription factor binding sites. CONCLUSIONS The activation of two proximal cis-regulatory sequences, induced by dengue virus infection, is mediated by chromatin remodeling mechanisms. Binding sites suggest a dengue virus infectioninduced participation of immunity transcription factors in the up-regulation of this gene. This suggests the participation of the AAEL006536 gene in the mosquito's antiviral innate immune response.
Potential Impact of "Take the Volume Pledge" on Access and Outcomes for Gastrointestinal Cancer Surgery.

OBJECTIVE To quantify the number of US hospitals that would meet "Take the Volume Pledge" (TVP) volume thresholds and compare outcomes at hospitals meeting and not meeting TVP thresholds. SUMMARY BACKGROUND DATA TVP aims to regionalize complex cancer resections to hospitals meeting established annual average volume thresholds. There is little data describing the potential impact on patient access if this initiative were broadly implemented or the relationship between these volume thresholds and quality of oncologic care. METHODS Hospitals in the National Cancer Database (2006-2012) performing esophagectomy (n = 968), proctectomy (n = 1250), or pancreatectomy (n = 1068) were categorized based on frequency meeting TVP thresholds: always low volume (LV); low annual average and intermittently low volume (ILV); high annual average and intermittently high volume (IHV); always high volume (HV). Multivariable generalized estimating equations were used to evaluate the association between hospital TVP category, oncologic care processes, and perioperative outcomes. RESULTS Few hospitals met annual TVP thresholds (HV or IHV)-esophagectomy 1.6%; proctectomy 19.7%; pancreatectomy 6.6%. The majority of esophagectomy (77.8%) and pancreatectomy (53.4%) and 48.1% of proctectomy patients received care at hospitals not meeting annual TVP thresholds (LV or ILV). While performance for all three procedures was generally better at ILV, IHV, and HV hospitals relative to LV hospitals, there were few differences (none of which were consistent) when comparing ILV, IHV, and HV hospitals to each other. CONCLUSIONS AND RELEVANCE Few hospitals would meet TVP volume thresholds for complex cancer resections with little difference in outcomes between ILV, IHV, and HV hospitals. While a policy to regionalize complex surgical care may have merit, it could also compromise patient autonomy and limit access to care if patients are unable or unwilling to travel.
Evaluation of a pictorial method to obtain subject‐specific inertial properties in equine limb segments

Data describing segmental masses and moments of inertia (MOI) of limb segments are required for inverse dynamic calculations. In horses, these values are usually calculated using regression equations that have been developed from a limited number of horses representing a small number of breeds. The objective of the present study was to evaluate the performance of a scaling method and a pictorial method for estimating of the values of segmental masses, lengths, and MOI in the equine limb segments by comparing their output with the standard technique involving direct measurements. Limbs of 30 horses of various breeds and sizes were disarticulated post mortem. Segmental masses, lengths, and MOI were determined using a standard method based on weighing the segments, measuring their length with calipers, and estimating the MOI from the rotational frequency of a trifilar pendulum. The scaling method used a jack‐knifing procedure to avoid the need for two data sets. The pictorial method was based on digitization of two orthogonal photographs to determine segmental volumes, which were combined with published values for average segment densities to determine the inertial parameters. Scaling method and pictorial method provided comparable estimation of segmental messes and lengths, but the scaling method performed better in estimating segmental MOI. The scaling method worked well enough in the majority of horses but there were a few horses in which it was less effective. The pictorial method sometimes showed a bias correctable by regression equations but it may not warrant the additional effort unless for specific cases.
Upholding the Rule of Law in Informal International Lawmaking Processes

AbstractNew, alternative, forms of cross-border cooperation, in particular processes of informal international lawmaking (‘IN-LAW’), have emerged and gained prominence since the 2000s in response to an increasingly diverse, networked, and knowledge-based society. This transformation impacts on traditional notions of public international law as well as on the conceptualization of an emerging international rule of law. This is all the more the case given the tendency to emphasise the formal characteristics of the latter. The present article, nevertheless, challenges the assumption that informal international law is, because of its informal nature, by definition incompatible with a rule of law approach. The article thereto reintroduces a negative (shielding society from arbitrariness) and a positive (providing requirements for lawmaking) conception of the rule of law. First, it identifies actors and processes of informal international lawmaking and elucidates the extent of their reliance on legal principles as opposed to the wielding of arbitrary power on the international plane. Second, it operationalises a rule of law approach in the three phases of informal lawmaking processes (lawmaking per se, law-application and accountability). As such, it discusses how a number of concrete rule of law requirements related to participation, procedural guarantees, accessibility of norms, and accountability mechanisms are implemented. To conclude, it is submitted that rule of law theories can be reconciled with IN-LAW, without affecting the flexibility that is fundamental to the non-traditional norms produced at the global level.
Managing yield: a marketing perspective

Yield Management has been successfully adopted by the airline industry following deregulation of the US airlines in the 1970s. As a management tool for enhancing profit Yield Management has been adopted within the accommodation division of hotels as a means to increase occupancy and room rates simultaneously. This paper presents the key stages in a Yield Management system and highlights the link between Yield Management and the marketing function within hotels. The authors present five 'Yield Marketing Practices', which are essential for the effective implementation of Yield Management, and introduce a 'Yield Segmentation Process' to direct the collection of some essential marketing data.
Preliminary Data Errors and Their Impact on the Forecast Error of Simultaneous-Equations Models

Econometric models, especially when designed for forecasting purposes, tend to use updated economic series, the last figures(s) of which embed first-published or preliminary data errors. This article identifies and assesses the contribution of errors in preliminary data to the forecast error and to the forecast error variance of linear dynamic simultaneous equation models. The effect of preliminary data errors is shown to be pervasive, although not necessarily weighty. The suggested decomposition of the forecast error is applied to a small macroeconometric model of the Italian economy.
Bank Loan Announcements and Borrower Stock Returns Before and During the Recent Financial Crisis

The impact of U.S. bank loan announcements on the stock prices of the corporate borrowers has been decreasing during the two last decades with estimated two-day cumulative abnormal returns slipping from almost 200 basis points in the beginning of the 1980s to close to zero by the turn of the Century. We estimate excess returns before and after the onset of the most recent financial crisis. We find that while prior to August 2007 returns were indeed close to zero, afterwards returns jump back up to around 200 basis points. We surmise that in a booming credit market the certification of corporate borrowers by banks started to play a lesser role, while during the crisis the banks’ role was revitalized. Consistent with this interpretation we find that after August 2007 excess returns increase especially for loans with a longer maturity, and for smaller, levered, less profitable or lowly rated firms.
The DOT1L inhibitor pinometostat reduces H3K79 methylation and has modest clinical activity in adult acute leukemia.

Pinometostat (EPZ-5676) is a first-in-class small-molecule inhibitor of the histone methyltransferase disrupter of telomeric silencing 1-like (DOT1L). In this phase 1 study, pinometostat was evaluated for safety and efficacy in adult patients with advanced acute leukemias, particularly those involving mixed lineage leukemia (MLL) gene rearrangements (MLL-r) resulting from 11q23 translocations. Fifty-one patients were enrolled into 6 dose-escalation cohorts (n = 26) and 2 expansion cohorts (n = 25) at pinometostat doses of 54 and 90 mg/m2 per day by continuous intravenous infusion in 28-day cycles. Because a maximum tolerated dose was not established in the dose-escalation phase, the expansion doses were selected based on safety and clinical response data combined with pharmacodynamic evidence of reduction in H3K79 methylation during dose escalation. Across all dose levels, plasma pinometostat concentrations increased in an approximately dose-proportional fashion, reaching an apparent steady-state by 4-8 hours after infusion, and rapidly decreased following treatment cessation. The most common adverse events, of any cause, were fatigue (39%), nausea (39%), constipation (35%), and febrile neutropenia (35%). Overall, 2 patients, both with t(11;19), experienced complete remission at 54 mg/m2 per day by continuous intravenous infusion, demonstrating proof of concept for delivering clinically meaningful responses through targeting DOT1L using the single agent pinometostat in MLL-r leukemia patients. Administration of pinometostat was generally safe, with the maximum tolerated dose not being reached, although efficacy as a single agent was modest. This study demonstrates the therapeutic potential for targeting DOT1L in MLL-r leukemia and lays the groundwork for future combination approaches in this patient population. This clinical trial is registered at www.clinicaltrials. gov as NCT01684150.
Innovation in Retirement Savings Policy: The New Zealand Experience

Abstract New Zealand has adopted a unique approach among OECD countries to the policy issue of retirement savings. New Zealand has no compulsion for retirement savings and, for the 20 years prior to 2007, has also had no tax incentives for retirement savings. In 2007, the KiwiSaver scheme was implemented: a unique compulsory “opt-in”, voluntary “opt-out” scheme, with financial incentives for participation. The reduction of the incentive to 2 per cent of salary, with a change of government in November 2008, has demonstrated that the innovative scheme is vulnerable to political manipulation.
Second-Home Owners: Escaping, Investing or Retiring?

Abstract This article employs the 2006 EU Survey on Income and Living Conditions to examine the characteristics of second-home owners in the Republic of Ireland. Its purpose is to explore the relevance to the Irish case of the three key demand-side drivers of second-home ownership which are most prominent in this literature. These are: compensation – the view that households purchase second homes in order to compensate for deficiencies in their primary residence; life cycle – which links second-home ownership to retirement or future retirement plans; and affluence – which links second home purchase to wealth, the availability of mortgage credit and investment concerns. It finds that the recent growth in second-home ownership has been driven primarily by affluence and that compensation and lifestyle are less relevant drivers in the Irish case.
Beleaguered? Be Damned! Be Gone!

At the insistence of colleagues, the author reluctantly assumed administrative responsibilities for his school of social work, giving up the teaching and research duties he truly enjoyed. In this narrative, the author shares some of his experiences (not all enjoyable) in that position; the mismatch of his own interests with the position s responsibilities, and his eventual resolution of the problem - read that 'resignation from the position '. Forget Vini! Vidi! Vieil More apropos is Beleaguered? Be Damned! Be Gone!
Preliminary assessment of stable nitrogen and oxygen isotopic composition of USGS51 and USGS52 nitrous oxide reference gases and perspectives on calibration needs.

RATIONAL: Despite a long history and growing interest in isotopic analyses of N2O, there is a lack of isotopically characterized N2O isotopic reference materials (standards) to enable normalization and reporting of isotope‐delta values. Here we report the isotopic characterization of two pure N2O gas reference materials, USGS51 and USGS52, which are now available for laboratory calibration (https://isotopes.usgs.gov/lab/referencematerials.html). METHODS: A total of 400 sealed borosilicate glass tubes of each N2O reference gas were prepared from a single gas filling of a high vacuum line. We demonstrated isotopic homogeneity via dual‐inlet isotope‐ratio mass spectrometry. Isotopic analyses of these reference materials were obtained from eight laboratories to evaluate interlaboratory variation and provide preliminary isotopic characterization of δ15N, δ18O, δ15Nα, δ15N, and site preference (SP) measurements. RESULTS: Isotopic homogeneity of USGS51 and USGS52 was demonstrated for both USGS51 and USGS52 by one‐sigma standard deviations associated with the determinations of δ15N, δ18O, δ15Nα, δ15N and SP of 0.12 mUr or better. The one‐ sigma standard deviations of SP measurements of USGS51 and USGS52 reported by eight laboratories participating in the interlaboratory comparison were 1.27 and 1.78 mUr, respectively. This document is the accepted manuscript version of the following article: Ostrom, N. E. , Gandhi, H. , Coplen, T. B. , Toyoda, S. , Böhlke, J. K. , Brand, W. A. , . Yoshida, N. (2018). Preliminary assessment of stable nitrogen and oxygen isotopic composition of USGS51 and USGS52 nitrous oxide reference gases and perspectives on calibration needs. Rapid Communications in Mass Spectrometry, 32(15), 1207-1214. https://doi.org/10.1002/rcm.8157
Working Parents and the Welfare State: Family Change and Policy Reform in Scandinavia

1. Introduction: changes in the social order 2. Politicising childcare 3. Work, family and the welfare state: problems of reconciliation 4. Parental leave: childcare refamilised 5. From mother's wage to parental choice: cash benefits for childcare 6. Childcare as a social right: family change and policy reform.
Survival by Association: Supply Management Landscapes of the Eastern Caribbean

Although the four islands have similar colonial backgrounds and more-or-less parallel development of the postwar banana industry, Welch finds dramatic variations in land use from island to island. She argues that the most critical factor in differences in land use is not politico-economic affiliation, agrarian structures, or the physical environment but the growers' associations that regulate the banana industries. She provides an account of the origin and development of banana growers' associations in the Eastern Caribbean, assesses the impact and influence of their policies and activities, and examines the way in which both associations and land-use patterns have evolved since the 1960s. Survival by Association addresses an issue of crucial importance not only for the banana growers of the Eastern Caribbean but for all developing countries whose economies are in jeopardy as a result of major realignments in patterns of world trade.
Female Employees’ Work Family Conflict and Job Satisfaction in Hospitality

Along with tourism industry rapid development, more and more female employees have been working in this field since Hainan to be build to an international tourism destination. And as the tourism industry rapidly development and hospitality need more labor to fit this trend, more local female employees are currently working related to the hospitality industry. However, the special job characteristics of the hotel such as the working environment, work shift and psychological pressure, female employees will have a big challenge in job satisfaction facing the conflict between work and family. In this paper, we will investigate these relations among work-family conflict, job satisfaction and turn over of female hotel employees in Haikou city, focusing on the effects of job satisfaction and job turn over under the organizational support based on the role perception of their job. The results of this research provide corresponding sustainable development policies for the local Government, hotel enterprises and other related organizations about how to deduce working pressure, conflict level of work-family and job turn-over for female hotel employees. Index Terms - Work-family Conflict, Job Satisfaction, Female Employees, and Hospitality.
An Empirical Model Comparison for Valuing Crack Spread Options

In this paper, we investigate the pricing of crack spread options. Particular emphasis is placed on the question of whether univariate modeling of the crack spread or explicit modeling of the two underlyings is preferable. Therefore, we contrast a bivariate GARCH volatility model for cointegrated underlyings with the alternative of modeling the crack spread directly. Conducting an empirical analysis of crude oil/heating oil and crude oil/gasoline crack spread options traded on the New York Mercantile Exchange, the more simplistic univariate approach is found to be superior with respect to option pricing performance.