Miracle-dz/UniFAR-FTUs huggingface dataset:
Motion of Inclusion Induced by a Direct Current and a Temperature Gradient

We have analyzed the migration of spherical and cylindrical inclusions under a direct current and a thermal gradient in an infinite medium and near a planar boundary. Our study of inclusion motion in an infinite medium is concerned primarily with the application of the marker‐motion technique to measure mass transport in the lattice. It is shown that, in addition to the lattice motion, there are contributions to marker movement coming from mass transport by surface and volume diffusion, which is induced by the change of potential gradient on the marker surface. To measure the true lattice velocity, the marker used must be a good insulator compared to the matrix material, and its size should exceed a few microns. The study of inclusion motion near a boundary is for analyzing pore migration by electromigration in thin films. Three cases have been considered, which include a spherical pore near a plane and between two planes and a cylindrical pore connected to two planes. We concluded that the pore migration.
Neonatal testosterone voids sexually differentiated microglia morphology and behavior

The involvement of immunity in psychiatric disorders, such as anxiety, is typified by the morphologic adaptation of microglia, immune cells of the brain, to anxiogenic stimuli. We previously reported sexually differentiated microglia morphology in adult rodents, in brain locations implicated in anxiety, including the pre-frontal cortex. These physiologic differences likely drive sex-dependent patterns of microglia morphologic remodeling in response to varied stress conditions in different periods of life, that correlate with sex-dependent behavioral adaptation to anxiogenic stimuli. The time-window of appearance of sex differences in microglia, correlating with sex-specific behavioral performance in anxiogenic conditions are still unknown. In rodents, a postnatal peak of the sexual hormone testosterone is determinant for the so-called brain masculinization and sex-determined behavioral traits. In the present work we aim to clarify if differences in microglia morphology are present at birth or can be driven by postnatal testosterone and impacts on the ability to deal with an anxiogenic context. Differences in microglia morphology are not present at birth, but are observable at adolescence (increased complexity of male microglia, particularly in branches more proximal to the soma), when differences in behavior are also observed. Our data also show that adolescent females neonatally treated with testosterone exhibit masculinized microglia and behavior. Importantly, between adolescence and adulthood, a sex-determined shift in the pattern of complexity takes place and microglia from females become more complex. When testosterone is administered, this morphological effect is partially abolished, approximating microglia and behavior to the male phenotype.
Systematic Identification and Comparison of the Expressed Profiles of Exosomal MiRNAs in Pigs Infected with NADC30-like PRRSV Strain

Simple Summary Exosomes play a unique role in virus infection, antigen presentation, and suppression/promotion of body immunity. Porcine reproductive and respiratory syndrome virus (PRRSV) is one of the most damaging pathogens in the pig industry. Here, we used the PRRSV NADC30-like CHsx1401 strain to artificially infect 42-day-old pigs, isolate serum exosomes, and identify 33 significantly differentially expressed (DE) exosomal miRNAs between infection and control groups, and 18 DE miRNAs associated with PRRSV infection and immunity were screened as potential functional molecules involved in the regulation of PRRSV virus infection by exosomes. Abstract Exosomes are biological vesicles secreted and released by cells that act as mediators of intercellular communication and play a unique role in virus infection, antigen presentation, and suppression/promotion of body immunity. Porcine reproductive and respiratory syndrome virus (PRRSV) is one of the most damaging pathogens in the pig industry and can cause reproductive disorders in sows, respiratory diseases in pigs, reduced growth performance, and other diseases leading to pig mortality. In this study, we used the PRRSV NADC30-like CHsx1401 strain to artificially infect 42-day-old pigs and isolate serum exosomes. Based on high-throughput sequencing technology, 305 miRNAs were identified in serum exosomes before and after infection, among which 33 miRNAs were significantly differentially expressed between groups (13 relatively upregulated and 20 relatively downregulated). Sequence conservation analysis of the CHsx1401 genome identified 8 conserved regions, of which a total of 16 differentially expressed (DE) miRNAs were predicted to bind to the conserved region closest to the 3′ UTR of the CHsx1401 genome, including 5 DE miRNAs capable of binding to the CHsx1401 3′ UTR (ssc-miR-34c, ssc-miR-375, ssc-miR-378, ssc-miR-486, ssc-miR-6529). Further analysis revealed that the target genes of differentially expressed miRNAs were widely involved in exosomal function-related and innate immunity-related signaling pathways, and 18 DE miRNAs (ssc-miR-4331-3p, ssc-miR-744, ssc-miR-320, ssc-miR-10b, ssc-miR-124a, ssc-miR-128, etc.) associated with PRRSV infection and immunity were screened as potential functional molecules involved in the regulation of PRRSV virus infection by exosomes.
Online Adaptive Generation of Critical Boundary Scenarios for Evaluation of Autonomous Vehicles

Testing and evaluation are critical steps in the development and deployment of autonomous vehicles (AVs). This paper aims to provide an online adaptive generation framework for critical boundary driving scenarios (CBDS) with flexible complexity and diversity. Both static scenarios and dynamic scenarios are comprehensively investigated based on real traffic flow data, where the generated static scenarios contain variables of drivable area, weather visibility, and road friction coefficient on autonomous vehicles, and the generated dynamic scenarios consider the effects of mixed traffic streams of AVs, human-driven vehicles, bicycles, and pedestrians. Two complexity models are proposed to characterize the complexity of static scenarios and dynamic scenarios separately, which help to construct feedback for the adaptive generation of CBDS. The scenario-based test is carried out on a joint simulation platform, and the multi-dimensional evaluation system, including safety, driving comfort, driving performance, and traffic coordination, is developed to assess the performance of AVs. Based on the proposed complexity models and multi-dimensional evaluation system, the generation of CBDS is transformed into online environmental parameter optimization. Moreover, the naturalistic driving scenarios generation, scenario complexity calculation, intelligent driving algorithm execution, and intelligent driving evaluation are all concatenated together to form a closed loop so as to adaptively generate critical boundary driving scenarios. Extensive simulations are conducted at the intersection with two different types of intelligent driving algorithms, which show the effectiveness of the proposed framework.
Genome-Wide Analysis of the LATERAL ORGAN BOUNDARIES Domain (LBD) Members in Alfalfa and the Involvement of MsLBD48 in Nitrogen Assimilation

The LATERAL ORGAN BOUNDARIES DOMAIN (LBD) proteins, a transcription factor family specific to the land plants, have been implicated in multiple biological processes including organ development, pathogen response and the uptake of inorganic nitrogen. The study focused on LBDs in legume forage Alfalfa. The genome-wide analysis revealed that in Alfalfa 178 loci across 31 allelic chromosomes encoded 48 unique LBDs (MsLBDs), and the genome of its diploid progenitor M. sativa spp. Caerulea encoded 46 LBDs. Synteny analysis indicated that the expansion of Alfalfa LBDs was attributed to the whole genome duplication event. The MsLBDs were divided into two major phylogenetic classes, and the LOB domain of the Class I members was highly conserved relative to that of the Class II. The transcriptomic data demonstrated that 87.5% of MsLBDs were expressed in at least one of the six test tissues, and Class II members were preferentially expressed in nodules. Moreover, the expression of Class II LBDs in roots was upregulated by the treatment of inorganic nitrogen such as KNO3 and NH4Cl (0.3 mM). The overexpression of MsLBD48, a Class II member, in Arabidopsis resulted in growth retardance with significantly declined biomass compared with the non-transgenic plants, and the transcription level of the genes involved in nitrogen uptake or assimilation, including NRT1.1, NRT2.1, NIA1 and NIA2 was repressed. Therefore, the LBDs in Alfalfa are highly conserved with their orthologs in embryophytes. Our observations that ectopic expression of MsLBD48 inhibited Arabidopsis growth by repressing nitrogen adaption suggest the negative role of the transcription factor in plant uptake of inorganic nitrogen. The findings imply the potential application of MsLBD48 in Alfalfa yield improvement via gene editing.
Reconstruction of tridimensional objects with two different textures using Gaussian model

We present in this work the use of two Gaussian models that describe reflectance of two different textures for the reconstruction of tridimensional objects made of these textures. The textures of the objects are segmented using a combination of image processing techniques. These segmentations are correlated with the Gaussian model for corresponding texture, for the reconstruction of the tridimensional object. We show our preliminary experimental result and we discuss the advantages and disadvantages of the Gaussian models, which are compared with the traditional representation of the inverse square law of light.
Dairy Cows Offered Fresh Chicory Instead of Ensiled Pasture during an Acute Heat Challenge Produced More Milk and Had Lower Body Temperatures

Simple Summary Dairy cows are particularly susceptible to heat stress, and the type and amount of forage offered could affect their heat load during hot weather. Our aim was to determine the impact of offering dairy cows two different forage types at two different amounts. Cows offered chicory (low fiber) produced more milk and had a lower body temperature than cows that were offered pasture silage (high fiber). Overall, cows that were offered the high amount of forage ate more feed and produced more milk than cows that were offered the low amount, but there was no difference in body temperature between these cows. However, during the heat challenge, cows that were offered the high amount of forage had a greater body temperature than cows that were offered the low amount. This single disadvantage is not sufficient to justify the restriction of feed intake as a strategy for managing hot weather events. While feeding chicory to dairy cows appears to be beneficial, our experiment was not done under commercial conditions, so further work is necessary to confirm our findings. Abstract The frequency, duration, and intensity of heat waves in Australia are increasing. To reduce the impact of heat waves on milk production, novel management strategies are required. Altering the forage type and amount offered affect the heat load on dairy cows and offer potential strategies to ameliorate the effects of hot weather. Thirty-two multiparous, lactating Holstein–Friesian cows were assigned one of four dietary treatments: chicory high amount, chicory low amount, pasture silage high amount, or pasture silage low amount. These cows were exposed to a heat wave in controlled-environment chambers. Cows that were offered fresh chicory had similar feed intake to cows that were offered pasture silage (15.3 kg DM/d). However, cows that were offered chicory produced greater energy-corrected milk (21.9 vs. 17.2 kg/d) and had a lower maximum body temperature (39.4 vs. 39.6 °C) than cows that were offered pasture silage overall. Cows that were offered the high amount of forage had greater feed intake (16.5 vs. 14.1 kg DM/d) and energy corrected milk yield (20.0 vs. 17.9 kg/d) than cows that were offered the low amount, as intended, but with no difference in maximum body temperature (39.5 °C). We conclude that feeding chicory instead of pasture silage to dairy cows shows promise as a dietary strategy to ameliorate the effect of heat exposure, and there was no advantage in restricting feed amount.
Fast rate-distortion estimation and optimization for wavelet video coding

The motion compensated- and difference- residual frames of a typical video sequence displays strong energy localization in the spatial domain. SPIHT expends many bits describing the location of the areas of energy concentration, and at low rates, these bits, which do not contribute to a PSNR increase, are wasteful. The scheme to be described avoids this wastage by performing local rate-distortion estimation and spatial bit assignment to achieve global PSNR optimality. The key to the algorithm is an extremely fast and accurate R-D estimation scheme, which permits this algorithm to operate in real-time.
Effects of Repeated Sprints on Hamstring Active Shear Modulus Pattern and Neuromuscular Parameters in Football Players with and without Hamstring Strain Injury History—A Retrospective Study

The aim of the present study is to compare the effects of a (i) repeated sprint protocol on the sprint performance, hamstrings shear modulus pattern, and neuromuscular parameters between players with and without previous hamstring strain injury (HSI); and (ii) between limbs with HSI and their healthy contralateral limbs on the hamstrings shear modulus pattern and neuromuscular parameters. One-hundred-and-five professional and semiprofessional football field players were invited to participate in this study during the pre-season 2021/2022 (June–July), resulting in a sample size of 210 limbs with 46 sustaining HSI in the previous 2 years. No differences were seen between previously injured and healthy control players regarding their sprint performance, hamstrings shear modulus pattern, and neuromuscular parameters, except for the early rate of torque development (0–50 ms) with previously injured limbs in the biceps femoris long head (BFlh) displaying higher rates than their contralateral muscle (injured: 496.93 ± 234.22 Nm/s; contralateral 422.72 ± 208.29 Nm/s; p = 0.005; η2p = 0.469). Overall, the present study provides evidence for no differences regarding sprint performance, hamstrings load sharing pattern, and major neuromuscular parameters between players with previous HSI in the last 2 years and healthy control players. Therefore, the results can possibly suggest that the duration between injury and screening could recover the differences between injured-control and injured-contralateral groups.
Cross-Sectional Analysis of Family Factors Associated with Lifestyle Habits in a Sample of Italian Primary School Children: The I-MOVE Project

The acquisition of healthy dietary and exercise habits during childhood is essential for maintaining these behaviors during adulthood. In early childhood, parents have a profound influence on a child’s lifestyle pursuits, serving as both role models and decision-makers. The present study examines family factors as potential contributors to healthy lifestyle habits and their child’s overall diet quality among a sample of primary school children. A secondary aim is to evaluate several aspects of diet quality using the Mediterranean adaptation of the Diet Quality Index-International (DQI-I). This cross-sectional study involved 106 children enrolled in a primary school located in Imola, Italy. Data were collected from October to December 2019 using an interactive tool used to assess parent characteristics, children’s lifestyle, food frequency (ZOOM-8 questionnaire), and actigraph accelerometers to capture children’s physical activity and sedentary behavior. Adherence to the Mediterranean Diet (expressed by KIDMED Index) was positively associated with fathers’ educational level, parental sport participation, and the parent’s overall nutritional knowledge. Higher mothers’ educational level was inversely associated with children’s leisure screen time. Parents’ nutritional knowledge was positively related to children’s average daily minutes of organized sport activities. The better score for DQI-I was for consumption adequacy, followed by variety and moderation. The lowest score was for overall balance. The present study reinforces the importance of family factors in young children’s lifestyle choices, particularly their dietary, leisure time, and exercise habits.
Imaging of a silicon pn junction under applied bias with scanning capacitance microscopy and Kelvin probe force microscopy

Scanning capacitance microscopy (SCM) and Kelvin probe force microscopy (KPFM) are used to image the electrical structure of a silicon pn junction under applied bias. With SCM, the carrier density inside a diode is imaged directly. With KPFM, the surface potential distribution of an operating diode is measured, revealing different behavior from that in bulk. The surface potential drop is extended deep into the lightly p-doped region at reverse bias, reflecting the existence of the surface space-charge region as confirmed by the numerical simulation.
Surface brightness profiles of 10 comets

CCD photometric observations of the comae of 10 comets, obtained at the 4-m and 2.1-m telescopes at KPNO during 1985-1986 using filters centered at 700.5, 650.0, or 546.0 nm, are reported. The data are presented in extensive tables and graphs and characterized in detail. The radial surface brightness profiles are shown to be steeper than predicted by an idealized spherically symmetric steady-state comet model, the steepness increasing with the projected distance from the nucleus. These profiles are attributed, on the basis of Monte Carlo simulations, to imperfect coupling between the sublimated gas and the optically dominant grains of the coma. 21 references.
Cohesive zone representation and junction partitioning for crystal plasticity analyses

A novel scheme is presented for incorporating finite thickness cohesive interfaces in virtual grain structures for crystal plasticity finite element (CPFE) analyses of intergranular crack initiation and propagation. A Voronoi tessellation model is used to define the virtual grain structure, with automatically generated nonzero thickness cohesive zones (CZs) representing the grain boundaries and multiple junctions. An efficient grain boundary offsetting algorithm is presented, and issues related to automatically partitioning multiple junctions are discussed. Two feasible junction partitioning schemes are presented, the second of which has the advantage of partitioning junctions using uniform quadrilateral elements and naturally defining their normal and tangential directions. For the second scheme, a rule‐based method is presented that carries out the preliminary meshing of CZ junctions, including data representation, edge event processing, and cut and trim operations. A virtual grain structure modelling system, VGRAIN, is introduced to implement the proposed CZ junction partitioning method and directly generate meshed virtual grain structures with CZ grain boundaries for CPFE studies. To demonstrate the proposed junction partitioning and CZ representation schemes, two finite strain CPFE simulations are presented for plane strain uniaxial tension and three‐point bending, demonstrating large‐scale crack initiation and propagation under shear and opening modes. Copyright © 2012 John Wiley & Sons, Ltd.
Micro-Evolutionary Processes in Armeria maritima at Metalliferous Sites

Tolerance to heavy metals in plants is a model process used to study adaptations to extremely unfavorable environments. One species capable of colonizing areas with high contents of heavy metals is Armeria maritima (Mill.) Wild. A. maritima plants growing in metalliferous areas differ in their morphological features and tolerance levels to heavy metals compared to individuals of the same species growing in non-metalliferous areas. The A. maritima adaptations to heavy metals occur at the organismal, tissue, and cellular levels (e.g., the retention of metals in roots, enrichment of the oldest leaves with metals, accumulation of metals in trichomes, and excretion of metals by salt glands of leaf epidermis). This species also undergoes physiological and biochemical adaptations (e.g., the accumulation of metals in vacuoles of the root’s tannic cells and secretion of such compounds as glutathione, organic acids, or HSP17). This work reviews the current knowledge on A. maritima adaptations to heavy metals occurring in zinc–lead waste heaps and the species’ genetic variation from exposure to such habitats. A. maritima is an excellent example of microevolution processes in plants inhabiting anthropogenically changed areas.
Carbon nanotubes in nanostructured films: Potential application as amperometric and potentiometric field‐effect (bio‐)chemical sensors

The assembly of carbon nanotubes (CNTs) into nanostructured films is attractive for producing functionalized hybrid materials and (bio‐)chemical sensors, but this requires experimental methods that allow for control of molecular architectures. In this study, we exploit the layer‐by‐layer (LbL) technique to obtain two types of sensors incorporating CNTs. In the first, LbL films of alternating layers of multi‐walled carbon nanotubes (MWNTs) dispersed in polyaminoamide (PAMAM) dendrimers and nickel phthalocyanine (NiTsPc) were used in amperometric detection of the neurotransmitter dopamine (DA). The electrochemical properties evaluated with cyclic voltammetry indicated that the incorporation of MWNTs in the PAMAM‐NT/NiTsPc LbL films led to a 3‐fold increase in the peak current, in addition to a decrease of 50 mV in the oxidation potential of DA. The latter allowed detection of DA even in the presence of ascorbic acid (AA), a typical interferent for DA. Another LbL film was obtained with layers of PAMAM and single‐walled carbon nanotubes (SWNTs) employed in field‐effect‐devices using a capacitive electrolyte–insulator–semiconductor structure (EIS). The adsorption of the film components was monitored by measuring the flat‐band voltage shift in capacitance–voltage (C –V) curves, caused by the charges from the components. Constant‐capacitance (ConCap) measurements showed that the EIS‐PAMAM/SWNT film displayed a high pH sensitivity (ca. 54.5 mV/pH), being capable of detecting penicillin G between 10–4 mol L–1 and 10–2 mol L–1, when a layer of penicillinase was adsorbed atop the PAMAM/SWNT film. (© 2009 WILEY‐VCH Verlag GmbH & Co. KGaA, Weinheim)
The Design, Education and Evolution of a Robotic Baby

Inspired by Alan Turing's idea of a child machine, in this article, we introduce the formal definition of a robotic baby, an integrated system with minimal world knowledge at birth, capable of learning incrementally and interactively, and adapting to the world. Within the definition, fundamental capabilities and system characteristics of the robotic baby are identified and presented as the system-level requirements. As a minimal viable prototype, the Baby architecture is proposed with a systems engineering design approach to satisfy the system-level requirements, which has been verified and validated with simulations and experiments on a robotic system. We demonstrate the capabilities of the robotic baby in natural language acquisition and semantic parsing in English and Chinese, as well as in natural language grounding, natural language reinforcement learning, natural language programming, and system introspection for explainability. The education and evolution of the robotic baby are illustrated with real-world robotic demonstrations. Inspired by the genetic inheritance in human beings, knowledge inheritance in robotic babies and its benefits regarding evolution are discussed.