Miracle-dz/UniFAR-FTUs huggingface dataset:
DISCOVERY OF A GeV BLAZAR SHINING THROUGH THE GALACTIC PLANE

The Fermi Large Area Telescope (LAT) discovered a new gamma-ray source near the Galactic plane, Fermi J0109+6134, when it flared brightly in 2010 February. The low Galactic latitude (b = −1.°2) indicated that the source could be located within the Galaxy, which motivated rapid multi-wavelength follow-up including radio, optical, and X-ray observations. We report the results of analyzing all 19 months of LAT data for the source, and of X-ray observations with both Swift and the Chandra X-ray Observatory. We determined the source redshift, z = 0.783, using a Keck Low-Resolution Imaging Spectrometer observation. Finally, we compiled a broadband spectral energy distribution (SED) from both historical and new observations contemporaneous with the 2010 February flare. The redshift, SED, optical line width, X-ray absorption, and multi-band variability indicate that this new GeV source is a blazar seen through the Galactic plane. Because several of the optical emission lines have equivalent width >5 Å, this blazar belongs in the flat-spectrum radio quasar category.
The Effect of Gender Identity on Perceptions of Authority Figures’ Racial Comments

ABSTRACT Social identity affects perceptions of leaders and subordinates in organizations. This investigation examined gender identity an aspect of social identity. Utilizing quantitative and qualitative survey methods, we theorized that gender identity affects perceptions of racism by authority figures. The quantitative results indicated that white women participants with a low gender identity were more likely to perceive racism by a low-status authority figure (e.g., a black individual) who made a derogatory racial comment toward white students than when a high-status group member authority figure (i.e., a white individual) made similar comments. This suggests that women have low feelings of solidarity with oppressed racial groups when they have a low gender identity. However, the qualitative results indicated that, overall, more women than men perceived racism in negative racial comments by the authority figure, no matter the authority figure’s social status.
Is Cortisol Excretion Independent of Menstrual Cycle Day? A Longitudinal Evaluation of First Morning Urinary Specimens

Background Cortisol is frequently used as a marker of physiologic stress levels. Using cortisol for that purpose, however, requires a thorough understanding of its normal longitudinal variability. The current understanding of longitudinal variability of basal cortisol secretion in women is very limited. It is often assumed, for example, that basal cortisol profiles do not vary across the menstrual cycle. This is a critical assumption: if cortisol were to follow a time dependent pattern during the menstrual cycle, then ignoring this cyclic variation could lead to erroneous imputation of physiologic stress. Yet, the assumption that basal cortisol levels are stable across the menstrual cycle rests on partial and contradictory evidence. Here we conduct a thorough test of that assumption using data collected for up to a year from 25 women living in rural Guatemala. Methodology We apply a linear mixed model to describe longitudinal first morning urinary cortisol profiles, accounting for differences in both mean and standard deviation of cortisol among women. To that aim we evaluate the fit of two alternative models. The first model assumes that cortisol does not vary with menstrual cycle day. The second assumes that cortisol mean varies across the menstrual cycle. Menstrual cycles are aligned on ovulation day (day 0). Follicular days are assigned negative numbers and luteal days positive numbers. When we compared Models 1 and 2 restricting our analysis to days between −14 (follicular) and day 14 (luteal) then day of the menstrual cycle did not emerge as a predictor of urinary cortisol levels (p-value >0.05). Yet, when we extended our analyses beyond that central 28-day-period then day of the menstrual cycle become a statistically significant predictor of cortisol levels. Significance The observed trend suggests that studies including cycling women should account for day dependent variation in cortisol in cycles with long follicular and luteal phases.
VARIATION IN SOIL FERTILITY AND CAPACITY FOR SUPPLYING SOIL NUTRIENTS IN A HEDGEROW INTERCROPPING SYSTEM WITH DIFFERENT TREE SPECIES IN THE UPCOUNTRY WET ZONE OF SRI LANKA

Sloping agricultural land technology (SALT), a form of hedgerow intercropping (HI) system, has been accepted as an appropriate land management practice to overcome some soil related constraints faced by farmers in marginal lands in the wet zone of Sri Lanka. Despite its effectiveness in soil conservation and soil fertility improvement, farmers are reluctant to adopt this practice due to the lack of immediate monetary returns. The lack of expected nutrient inputs through hedgerow mulch and possible tree-crop competition for essential resources seems to be the main drawbacks. In order to test some of these aspects, a study was carried out to assess the soil fertility status after 4 years of HI on the slopes of the wet zone of Sri Lanka, with a special emphasis on the nutrient redistribution in alleyways due to the establishment of contour hedgerows. After 4 years of HI, some soil chemical parameters such as concentrations of organic C, total N, mineralizable N, and organic P were higher in the SALT-HI plot than that of farmer-managed vegetable plot and the abandoned tea land. However, 4 years of HI on the slopes at Doragalla, some chemical parameters showed a significant position effect down the slope compared to the control sites, with a tendency for accumulating nutrients immediately under the hedges compared to open alleyways, yielding a distinct ‘saw-tooth’ pattern down the slope. The organic C and total N concentrations were significantly higher under hedges than in the open alleyways, where the crops were grown. This nutrient patchiness was not present in the two control sites without hedgerows. This nutrient patchiness seems to be a direct consequence of establishing hedgerows along contours and hence will be a crucial factor determining the fate of this agroforestry system in Sri Lanka.
Cortical Sensory Plasticity in a Model of Migraine with Aura

The migraine attack is characterized by alterations in sensory perception, such as photophobia or allodynia, which have in common an uncomfortable amplification of the percept. It is not known how these changes arise. We evaluated the ability of cortical spreading depression (CSD), the proposed mechanism of the migraine aura, to shape the cortical activity that underlies sensory perception. We measured forepaw- and hindpaw-evoked sensory responses in rat, before and after CSD, using multielectrode array recordings and two-dimensional optical spectroscopy. CSD significantly altered cortical sensory processing on a timescale compatible with the duration of the migraine attack. Both electrophysiological and hemodynamic maps had a reduced surface area (were sharpened) after CSD. Electrophysiological responses were potentiated at the receptive field center but suppressed in surround regions. Finally, the normal adaptation of sensory-evoked responses was attenuated at the receptive field center. In summary, we show that CSD induces changes in the evoked cortical response that are consistent with known mechanisms of cortical plasticity. These mechanisms provide a novel neurobiological substrate to explain the sensory alterations of the migraine attack.
Optimal trajectory planning by Big Bang-Big Crunch algorithm

Path planning is an interesting topic which is affected by lots of variables, as: time, energy, torque and stability. In this study, a new method based on Big Bang-Big Crunch algorithm is proposed to find optimum values of the parameters of a path and a cost function in order to minimize applied torque and tracking error. For this purpose the mathematical model of the manipulator is derived with mainly used methods, Denavit-Hartenberg, Jacobian and Euler-Lagrange methods. By using classical robot modeling methods, Big Bang-Big Crunch algorithm searched for the optimum trajectory and found the optimum value of the cost function.
Possible Role of –374T/A Polymorphism of RAGE Gene in Longevity

Demographic and social changes in the last decades have resulted in improvements in health and longevity. The survival of elderly people has improved significantly and thus centenarians are becoming the fastest growing population group. Environmental, genetic, and accidental factors have influenced the human life span. Researchers have gained substantial evidence that advanced glycation end products may play an important role in the processes of physiological aging. The aim of the present study was to investigate any differences in the frequencies of –374T/A polymorphism in subjects aged >90 years and in middle-aged individuals. We observed association between the A allele and genotype homozygous for this allele (AA) with a longer life expectancy in the male population. In particular, there was a prevalence of AA genotype and A allele in long-living subjects and a prevalence of the allele T in middle-aged subjects, indicating a possible protective role of the allele A to aging. In conclusion, our results support the hypothesis that longevity is the result of a good functioning of the immune system and a presumable hyper-expression of variants of anti-inflammatory genes of immunity. The differences in the genetic regulation of inflammatory processes may influence the presence of age-related disorders.
Fundamental measure density functional theory for hard spherocylinders in static and time-dependent aligning fields

The recently developed fundamental measure density functional theory (Hansen-Goos and Mecke 2009 Phys. Rev. Lett. 102 018302) for an inhomogeneous anisotropic hard body fluid is used as a basic ingredient in treating the Brownian dynamics of hard spherocylinders. After discussing the relevance of a free parameter in the fundamental measure density functional for the isotropic–nematic transition in equilibrium, we discuss the equilibrium phase behaviour of hard spherocylinders in a static external potential which couples only to the orientations. For external potentials favouring rod orientations along the poles of the unit sphere, there is a well-known paranematic–nematic transition which ceases to exist above a threshold of the strength V0 of the external potential. However, when orientations along the equator are more favoured, in the plane of the potential energy V0 and density, there is a phase transition from paranematic to nematic for any strength, which becomes second order above a critical threshold of V0. The full equilibrium phase diagram in the V0–density plane is computed for a fixed rod aspect ratio of 5. For the equatorial cases, strength V0 is then oscillating in time and dynamical density functional theory is used to compute the evolution of the orientational distribution. A subtle resonance for increasing oscillation frequencies is detected if the oscillating V0 crosses the paranematic–nematic phase transition.
Quality Assurance: The Model of Quality Evaluation of Sport Exercises Achievement

This research is aimed to establish the model of quality evaluation of the achievement sport exercises. This study generated some products such as: (1) document of quality, which includes; a) exercises quality standard, b) procedures manual, c) works instruction (2) developing instruments of quality evaluation of the achievement sport exercises. This research used research and development approach and was divided in three parts, such as (1) needs analysis, (2) develop the instruments, and (3) implementation of the outcome and evaluation to discover the quality of exercises performed by clubs or achievement sports association in order to improve the quality of exercises continuously. This research used research and development approach. This study concluded that the model of quality of exercises can possibly be used to strengthen the quality progressively. Evaluation of exercises quality is undertaken based on the standard of sports quality compared to the real condition. Keyword: Evaluation, Quality, Exercise, Sport
A systematic analysis of the factors that determine the strength of pre‐mRNA splicing enhancers

We find that the strength of splicing enhancers is determined by the relative activities of the bound serine‐arginine (SR)‐rich splicing factors, the number of SR proteins within the enhancer complex and the distance between the enhancer and the intron. Remarkably, the splicing activity of the bound SR proteins is directly proportional to the number of RS tetrapeptide sequences within the RS domain. Quantitative analysis of the effects of varying the distance between the enhancer and the intron revealed that the splicing efficiency is directly proportional to the calculated probability of a direct interaction between the enhancer complex and the 3′ splice site. These data are consistent with a model in which splicing enhancers function by increasing the local concentration of SR proteins in the vicinity of the nearby intron through RNA looping.
Classification in Twitter via Compressive Sensing

In this paper we introduce a novel low dimensional method to perform topic detection and classification in Twitter. The proposed method first employs Joint Complexity to perform topic detection. Then, based on the nature of the data, we apply the theory of Compressive Sensing to perform topic classification by recovering an indicator vector, while reducing significantly the amount of information from tweets. In this paper we exploit datasets in various languages collected by using the Twitter streaming API, and achieve increased classification accuracy when comparing to state-of-the-art methods based on bag-of-words, along with several reconstruction techniques.
Towards a molecules production from DNA sequences based on clustering by 3D cellular automata approach and n-grams technique

Knowledge extraction from genomic data is important activity for the biologist. In order to extract the underlying biological knowledge, we based on the generic framework of Knowledge extraction from data. In this paper, we transformed DNA sequences into texts, the texts are indexed by TF-IDF and n-grams approach. Secondly, we grouped the similar DNA sequences by clustering; we applied bio-inspired method 3D cellular automata. Then we analyze the clustering results by the transformation of each DNA sequences into amino acids sequences according the standard genetic code, we concluded that, the clusters help the biologist to select DNA sequences can produce a kind of medicament (molecule) and their various derivatives (low concentration).
Phase-indexed ILC for control of underactuated walking robots

We propose a method for learning the nominal control input for virtual-constraints-based walking robots. The key problem in applying iterative learning control (ILC) to these systems is that the iterations are only approximately periodic. We develop a modified form of ILC that indexes previous iterations by a phase variable (a function of the state variables) rather than time. We show in experiments that the proposed method outperforms time-indexed ILC and a hybrid “resetting” form of ILC in terms of tracking error reduction and stability.
124Iodine: A Longer-Life Positron Emitter Isotope—New Opportunities in Molecular Imaging

124Iodine (124I) with its 4.2 d half-life is particularly attractive for in vivo detection and quantification of longer-term biological and physiological processes; the long half-life of 124I is especially suited for prolonged time in vivo studies of high molecular weight compounds uptake. Numerous small molecules and larger compounds like proteins and antibodies have been successfully labeled with 124I. Advances in radionuclide production allow the effective availability of sufficient quantities of 124I on small biomedical cyclotrons for molecular imaging purposes. Radioiodination chemistry with 124I relies on well-established radioiodine labeling methods, which consists mainly in nucleophilic and electrophilic substitution reactions. The physical characteristics of 124I permit taking advantages of the higher PET image quality. The availability of new molecules that may be targeted with 124I represents one of the more interesting reasons for the attention in nuclear medicine. We aim to discuss all iodine radioisotopes application focusing on 124I, which seems to be the most promising for its half-life, radiation emissions, and stability, allowing several applications in oncological and nononcological fields.
Monsters in the closet: Munchausen syndrome by proxy.

Eighteenth century German aristocrat Karl Friedrich Hieronymus Freiherr von Münchhausen was renowned for telling wildly exaggerated tales of travel and adventure.1 In 1786, Rudolf Raspe published versions of the baron’s imaginative tales in his book, The Surprising Adventures of Baron Munchausen. The medical profession has since borrowed the name of this famous raconteur to describe a group of individuals whose complaints are fabricated, but nonetheless so convincing that patients are subjected to needless hospitalizations, diagnostic tests, and even surgery.2 British physician Richard Asher, who first described Munchausen syndrome in 1951, noted that “the most remarkable feature of the syndrome is the apparent senselessness of it. Becoming a patient is the purpose of the syndrome. ”3
Lexical Rules: What are they?

Horizontal redundancy is inherent to lexica consisting of descriptions of fully formed objects. This causes an unwelcome expansion of the lexical database and increases parsing time. To climinate it, direct relations between descriptions of fully formed objects are often defined. These are additional to the (Typed Multiple) Inheritance Network which already structures the lexicon. Many implementations of horizontal relations, however, fail to generate lexical entries on a needs-driven basis, so eliminate neither the problem of lexicon expansion nor that of inefficient parsing. Alternatively, we propose that lexical entries are descriptions of objects open to contextual specification of their properties on the basis of constraints defined within the type system. This guarantees that only those grammatical lexical entries are infered that are needed for efficient parsing. The proposal is extremely modest, making use of only basic inference power and expressivity.
Dispatch and conflict-free routing of capacitated vehicles with storage stack allocation

Abstract Congested traffic networks impose great difficulties upon scheduling material transportation in industrial settings. Dispatching decisions become complex when, in addition to conflict-free routes, storage location must also be considered. The present paper integrates the dispatch and conflict-free routing of capacitated vehicles with the storage allocation problem and proposes a heuristic approach for minimising the total completion time of box pickup, delivery and relocation requests in a warehouse environment. The developed formulation models a warehouse setting in which boxes are stored in stacks and considers different forward and reverse speeds for the vehicles, real-world movement restrictions and a LIFO loading policy. The proposed approach is evaluated using two different metaheuristics and the results are compared against existing schedules prepared by an industry partner. Experimental results demonstrate the effectiveness of the proposed method for large-scale instances and highlight how improved storage allocation decisions can reduce service times.
A Real-Time Clinical Endoscopic System for Intraluminal, Multiplexed Imaging of Surface-Enhanced Raman Scattering Nanoparticles

The detection of biomarker-targeting surface-enhanced Raman scattering (SERS) nanoparticles (NPs) in the human gastrointestinal tract has the potential to improve early cancer detection; however, a clinically relevant device with rapid Raman-imaging capability has not been described. Here we report the design and in vivo demonstration of a miniature, non-contact, opto-electro-mechanical Raman device as an accessory to clinical endoscopes that can provide multiplexed molecular data via a panel of SERS NPs. This device enables rapid circumferential scanning of topologically complex luminal surfaces of hollow organs (e.g., colon and esophagus) and produces quantitative images of the relative concentrations of SERS NPs that are present. Human and swine studies have demonstrated the speed and simplicity of this technique. This approach also offers unparalleled multiplexing capabilities by simultaneously detecting the unique spectral fingerprints of multiple SERS NPs. Therefore, this new screening strategy has the potential to improve diagnosis and to guide therapy by enabling sensitive quantitative molecular detection of small and otherwise hard-to-detect lesions in the context of white-light endoscopy.
Error Controls for Broadcast Communication Systems: An Integer Programming Approach to UEP Coding Scheme and A Deterministic Approach to Network Coding

Traditional network protocols employ error control techniques for reliable information dissemination over noisy communication channels. In this dissertation, two main topics are investigated for efficient error controls over a broadcast channel. First, unequal error protection (UEP) coding schemes for multiuser communications are investigated, and we propose integer programming approaches to UEP coding and decoding. Second, reliable packet transmissions over a single-hop broadcast network are considered, and we propose a unified solution to use a deterministic network coding for a packet retransmission scheme and a packet-level forward error correction scheme. For multiuser communications over a broadcast channel, integer programming approaches are introduced to the construction and the decoding of a binary linear UEP code. First, optimal UEP codes are constructed from integer programming for maximum efficiency, and lower bounds of UEP codes
E 26 Transformation-Specific-1 ( ETS 1 ) and WDFY Family Member 4 ( WDFY 4 ) Polymorphisms in Chinese Patients with Rheumatoid Arthritis

E26 transformation-specific-1 (ETS1) and WDFY family member 4 (WDFY4) are closely related with systemic lupus erythematosus. We hypothesized that ETS1 and WDFY4 polymorphisms may contribute to rheumatoid arthritis (RA) susceptibility. We studied ETS1 rs1128334 G/A and WDFY4 rs7097397 A/G gene polymorphisms in 329 patients with RA and 697 controls in a Chinese population. Genotyping was done using matrix-assisted laser desorption/ionization time-of-flight mass spectrometry. When the WDFY4 rs7097397 AA homozygote genotype was used as the reference group, the AG genotype was associated with a significantly increased risk for RA. In the dominant model, when the WDFY4 rs7097397 AA homozygote genotype was used as the reference group, the AG/GG genotypes were associated with a significant increased susceptibility to RA. In stratification analyses, a significantly increased risk for RA associated with the WDFY4 rs7097397 AG genotype was evident among female patients, younger patients, C-reactive protein (CRP) negative patients and both anti-cyclic citrullinated peptide antibody (ACPA) OPEN ACCESS Int. J. Mol. Sci. 2014, 15 2713 positive patients and negative patients compared with the WDFY4 rs7097397 AA genotype. These findings suggested that WDFY4 rs7097397 A/G may be associated with the risk of RA, especially among younger, female patients, CRP-negative patients and both ACPA positive and negative patients. However, our results were obtained from a moderate-sized sample, and therefore this is a preliminary conclusion. To confirm these findings, validation by a larger study from a more diverse ethnic population is needed.