Miracle-dz/UniFAR-FTUs huggingface dataset:
Revitalizing the Malaysian Trade Union Movement: The Case of the Electronics Industry

The article takes an historic perspective on contemporary issues of trade union revival in Malaysia, focusing on the challenge of raising union density and analysing the process of organizing employees in the strategically important electronics industry. It concludes that the political support for transnational corporations in the electronics industry is declining. This strategic shift enables union activists to bypass enterprise and state-based unions and to establish larger, regionally based unions. However, newly organized unions have not yet overcome resistance from global corporations, nor have trade unions been included in the larger politics of development strategies. Unions must be part of a larger socio-political movement and regime change in order to overcome the restrictive labour laws as well as the anti-union practices of transnational corporations. Yet the majority of the peak union organizations prefer non-partisan engagement. In order to revitalize themselves, the unions must demonstrate to the Malaysian public that they are both relevant and important for increased productivity and that they can play a significant role in enabling Malaysia to move beyond the middle-income ‘trap’ towards a more developed market economy.
Lean management and HR function capability: the role of HR architecture and the location of intellectual capital

There has been an increasing interest in Lean thinking both in traditional manufacturing/engineering organizations and, more recently, in non-traditional/white-collar settings. Despite the potential benefits, organizations that have implemented lean are facing problems of sustainability. In this study, we examine the nexus between lean thinking and the role of HRM in helping with the sustainability of lean. This paper reports on how recent initiatives may be leading to changes in the ownership of the ‘intellectual capital’ surrounding lean thinking, new core expertise and the issue of where this expertise should lie. The study is based on 18 interviews with the senior managers responsible for the lean management activity and HR strategy within a dozen large organizations, both in traditional and non-traditional/white-collar organizations. It analyses expert opinions to identify the implicit strategies around lean implementation and generate insights into the spectrum of people-related issues needed for the success of lean and adjustments needed to HR architecture in terms of three core elements: skills and competencies that HR needs; implications for HR practices; and the essential role behaviours that these are intended to create amongst employees. It also examines where expertise and intellectual capital should lie, and identifies the structural solutions being pursued.
Rice xa 13 Recessive Resistance to Bacterial Blight Is Defeated by Induction of the Disease Susceptibility Gene Os-11 N 3

The rice (Oryza sativa) gene xa13 is a recessive resistance allele of Os-8N3, a member of the NODULIN3 (N3) gene family, located on rice chromosome 8. Os-8N3 is a susceptibility (S) gene for Xanthomonas oryzae pv oryzae, the causal agent of bacterial blight, and the recessive allele is defeated by strains of the pathogen producing any one of the type III effectors AvrXa7, PthXo2, or PthXo3, which are all members of the transcription activator-like (TAL) effector family. Both AvrXa7 and PthXo3 induce the expression of a second member of the N3 gene family, here named Os-11N3. Insertional mutagenesis or RNA-mediated silencing of Os-11N3 resulted in plants with loss of susceptibility specifically to strains of X. oryzae pv oryzae dependent on AvrXa7 or PthXo3 for virulence. We further show that AvrXa7 drives expression of Os-11N3 and that AvrXa7 interacts and binds specifically to an effector binding element within the Os-11N3 promoter, lending support to the predictive models for TAL effector binding specificity. The result indicates that variations in the TAL effector repetitive domains are driven by selection to overcome both dominant and recessive forms of resistance to bacterial blight in rice. The finding that Os-8N3 and Os-11N3 encode closely related proteins also provides evidence that N3 proteins have a specific function in facilitating bacterial blight disease.
The Journal of Macro Trends in Health and Medicine A Strategy for DNA Sequencing of CASQ 1 reveals no mutations associated with malignant hyperthermia

The aim of this study is to elucidate the relationships between susceptibility to MH (MHS) and genes encoding skeletal muscle Ca2+ channels and their accessory proteins. Selected exons of Calsequestrin1 demonstrated that no mutations or any novel genetic variants were identified in the UK malignant hyperthermia population. Investigating other candidate genes that contribute to the calcium release unit, e.g. HRC, different subunits of DHPR, and Calmodulin, may lead to the identification and characterisation of novel mutations or to the detection of association with MH susceptibility. Further linkage studies and DNA sequencing of other putative candidate genes other than RYR1, CACNA1S and CASQ1, are suggested to further elucidate MH phenotype/genotype discordance and MH heterogeneity.
Human Appropriation of Net Primary Production: Patterns, Trends, and Planetary Boundaries

Economic and population growth result in increasing use of biophysical resources, including land and biomass. Human activities influence the biological productivity of land, altering material and energy flows in the biosphere. The human appropriation of net primary production (HANPP) is an integrated socioecological indicator quantifying effects of human-induced changes in productivity and harvest on ecological biomass flows. We discuss how HANPP is defined, measured, and interpreted. Two principal approaches for constructing HANPP assessments exist: (a) In an area-specific approach, HANPP serves as an indicator of land-use intensity, gauging impacts on terrestrial ecosystems in a defined area; and (b) the consumption-based “embodied HANPP” approach allows assessment of impacts related to individual products or the aggregate consumption of nation-states. The HANPP framework can help to estimate upper limits for the biosphere's capacity to provide humanity with biomass for food, fiber, and bioenergy and to.
Metabolic syndrome in the Mediterranean region: Current status

Metabolic syndrome (MetS) is a cluster of metabolic abnormalities including abdominal obesity, impaired fasting glucose, hypertension and dyslipidemia. It seems to affect about one-fourth to one-fifth of the Mediterranean population, and its prevalence increases with age, being similar for both sexes and depending on the region and the definition used, with the National Cholesterol Education Program-Adult Treatment Panel-III (NCEP-ATPIII) definition being the most effective in the identification of glucose intolerance and cardiovascular risk. Except for these, MetS is associated with fatty liver disease, some forms of cancer, hypogonadism, and vascular dementia. The Mediterranean diet seems to be an ideal diet in patients with MetS, being rich in fibre, monounsaturated and polyunsaturated fats, and low in animal protein; and decreases the prevalence of MetS and cardiovascular disease risk. Except for weight loss, multifactorial intervention including insulin resistance reduction and normoglycemia, management of dyslipidemia, optimizing blood pressure and administration of low-dose aspirin for patients at high or moderately high cardiovascular disease (CVD) risk are additional targets. The present review provides current understanding about MetS in the Mediterranean region, focusing on its prevalence, clinical significance, and therapeutic strategy.
Islamic and Arab Cultural Influences in the South of the Philippines

It is not infrequent for some Filipino historians to write that the Filipino people have inherited a, great deal from both Oriental and Occidental cultures without losing their racial identity, and that before the coming of Spain and Christianity to the Philippines during the sixteenth century, the ancestors of the present-day Filipinos had commercial, political, and cultural relations with India, China, Japan, and the rest of Malaysia. This view, however, requires certain clarifications and qualifications. The term “Filipino” now-a-days is mainly a political one and generally denotes the native inhabitants of the Philippine Archipelago who are subject to a definite and internationally recognized central government. Seventy years or more ago, the native inhabitants of the Philippines were called “indios” and not “Filipinos”, as this latter term was reserved for Spaniards who were born in the Philippines, to distinguish them from those Spaniards who were born in Spain. Historically speaking, in spite of the fact that the present-day Filipinos and their ancestors belong to a wider race, they did not constitute a “people” in any political sense. This is not to deny that their ancestors shared in a common cultural matrix. But if they were a “people” in this sense, then they, with the present-day Indonesians and other Malays, belong to one people. As pointed earlier, the concept of a Filipino people belonging to one national community is a recent one, and the process of integrating them more and more into a national community is still going on. It might be meaningful to maintain that the different Malay peoples at present are segmented or divided into different political entities.
ENDOGENOUS CREDIT AND INVESTMENT CYCLES WITH ASSET PRICE VOLATILITY

It is commonly accepted that credit market frictions are an important source of macroeconomic fluctuations. But what is the link between the two? And what is the driving factor of asset prices volatility? To answer these questions, we have introduced a specific credit friction, limited commitment, in a general equilibrium model with production and investment in productive capital, where agents can trade bonds. The model always displays a stationary equilibrium where bonds are traded. More importantly, limited commitment may generate stochastic endogenous fluctuations driven by self-fulfilling volatile expectations (sunspots), yielding credit and investment cycles and bond price volatility consistent with data.
Signatures of quantum criticality in pure Cr at high pressure

The elemental antiferromagnet Cr at high pressure presents a new type of naked quantum critical point that is free of disorder and symmetry-breaking fields. Here we measure magnetotransport in fine detail around the critical pressure, Pc ∼ 10 GPa, in a diamond anvil cell and reveal the role of quantum critical fluctuations at the phase transition. As the magnetism disappears and T → 0, the magntotransport scaling converges to a non-mean-field form that illustrates the reconstruction of the magnetic Fermi surface, and is distinct from the critical scaling measured in chemically disordered Cr∶V under pressure. The breakdown of itinerant antiferromagnetism only comes clearly into view in the clean limit, establishing disorder as a relevant variable at a quantum phase transition.
Comparison of efficacy and safety between benidipine and hydrochlorothiazide in fosinopril-treated hypertensive patients with chronic kidney disease: protocol for a randomised controlled trial

Introduction Co-administration of a diuretic or calcium channel blocker with an ACE inhibitor are both preferred combinations in patients with hypertensive chronic kidney disease (CKD). According to the available evidence, it is still unknown which combination plays a more active role in renal protection. We hypothesised that a combination of fosinopril and benidipine may delay the progression of CKD more effectively than a combination of fosinopril and hydrochlorothiazide (HCTZ). Methods and analysis This study will be a multicentred, prospective, double-blind, randomised parallel controlled trial for hypertensive CKD patients in China. Patients will be randomised to one of two treatment groups: a combination of benidipine 4–8 mg/day and fosinopril 20 mg/day; or a combination of HCTZ 12.5–25 mg/day and fosinopril 20 mg/day. Patients will be followed up for 24 months after a month's fosinopril run-in. There will be dose-titration after 1 and 2 months. The primary endpoint is changes in estimated glomerular filtration rate (eGFR) from baseline to month 24. Secondary endpoints include changes in home blood pressure (BP), ambulatory BP, proteinuria, urinary albumin/creatinine ratio, and composite renal events in 24 months. Inclusion criteria are: age 18–80 years, non-dialysis CKD patients with eGFR >30 mL/min/1.73 m2, home BP >130 mm Hg systolic or BP >80 mm Hg diastolic at the screening and randomisation, and 24 hour proteinuria <3.5 g. Principal exclusions are hypertensive crisis, transplantation, cancer, severe diabetes complications, hyperkalaemia and severe allergy. The required sample size was 511 patients for detecting a difference in the change of eGFR (one sided α=0.025, power 1-β=0.90). Ethics and dissemination BEAHIT (Benidipine and Hydrochlorothiazide in Fosinopril Treated Chronic Kidney Disease Patients with Hypertension) was approved by Changzheng Hospital Ethics Committee (CZ-20160504-16). The outcomes will be published in a peer-reviewed journal. Trial registration number NCT02646397.
Affecting Factors on Risk-Adjusted Efficiency in Taiwan's Banking Industry

This study adopts a two-stage approach, data envelopment analysis (DEA) and tobit regression, to investigate the bank efficiency index and efficiency effect incorporated into account credit and market risk. The authors use the DEA method in the first stage to estimate bank cost efficiency, and the tobit regression model in the second stage to estimate efficiency effects. The empirical results are summarized as follows: First, results indicate that risk factors impact bank efficiency. Banks with a higher degree of nonperforming loans or value at risk will see efficiency decrease by incorporating account risk. Second, there is no significant difference with the bank efficiency index taking only credit risk or market risk into consideration, but there are significant differences on the bank efficiency index in situations without risk or with credit and/or market risks. Finally, the study notes that different bank efficiency indexes calculated according to different risks are affected by different factors. (JEL "G1, G21") Copyright 2006 Western Economic Association International.
Stochastic optimal scheduling for DC-linked multi-microgrids in distribution networks

This paper proposes a stochastic programming approach based on Conditional Value at Risk (CVaR) to measure the impact of prediction errors brought about by the renewable energy and load on DC-linked multi-microgrids coalition in the distribution network so that the system scheduling operator can achieve the lowest day-ahead scheduling cost at a certain risk. Due to the prediction errors of the renewable energy and load, stochastic programming is suitable for modeling. The validity of the method is verified by the multi-microgrids coalition containing three DC-linked microgrids of the IEEE 33-node distribution system by using actual renewable energy and three typical load data. Finally, this paper gives a comparison between deterministic and stochastic scheduling.
Cerebrospinal fluid markers to distinguish bacterial meningitis from cerebral malaria in children

Background . Few hospitals in high malaria endemic countries in Africa have the diagnostic capacity for clinically distinguishing acute bacterial meningitis (ABM) from cerebral malaria (CM). As a result, empirical use of antibiotics is necessary. A biochemical marker of ABM would facilitate precise clinical diagnosis and management of these infections and enable rational use of antibiotics. Methods. We used label-free protein quantification by mass spectrometry to identify cerebrospinal fluid (CSF) markers that distinguish ABM (n=37) from CM (n=22) in Kenyan children. Fold change (FC) and false discovery rates (FDR) were used to identify differentially expressed proteins. Subsequently, potential biomarkers were assessed for their ability to discriminate between ABM and CM using receiver operating characteristic (ROC) curves. Results. The host CSF proteome response to ABM ( Haemophilus influenza and Streptococcus pneumoniae) is significantly different to CM. Fifty two proteins were differentially expressed (FDR<0.01, Log FC≥2), of which 83% (43/52) were upregulated in ABM compared to CM. Myeloperoxidase and lactotransferrin were present in 37 (100%) and 36 (97%) of ABM cases, respectively, but absent in CM (n=22). Area under the ROC curve (AUC), sensitivity, and specificity were assessed for myeloperoxidase (1, 1, and 1; 95% CI, 1-1) and lactotransferrin (0.98, 0.97, and 1; 95% CI, 0.96-1). Conclusion. Myeloperoxidase and lactotransferrin have a high potential to distinguish ABM from CM and thereby improve clinical management. Their validation requires a larger cohort of samples that includes other bacterial aetiologies of ABM.
REVIEW Physiology of the pancreatic a -cell and glucagon secretion: role in glucose homeostasis and diabetes

The secretion of glucagon by pancreatic a -cells plays a critical role in the regulation of glycaemia. This hormone counteracts hypoglycaemia and opposes insulin actions by stimulating hepatic glucose synthesis and mobilization, thereby increasing blood glucose concentrations. During the last decade, knowledge of a -cell physiology has greatly improved, especially concerning molecular and cellular mechanisms. In this review, we have addressed recent ﬁndings on a -cell physiology and the regulation of ion channels, electrical activity, calcium signals and glucagon release. Our focus in this review has been the multiple control levels that modulate glucagon secretion from glucose and nutrients to paracrine and neural inputs. Additionally, we have described the glucagon actions on glycaemia and energy metabolism, and discussed their involvement in the pathophysiology of diabetes. Finally, some of the present approaches for diabetes therapy related to a -cell function are also discussed in this review. A better understanding of the a -cell physiology is necessary for an integral comprehension of the regulation of glucose homeostasis and the development of diabetes.
Building the northern Australia vision through creative industries: the case of Cairns in far north Queensland

This article focuses on the creative industries sector in the regional city of Cairns in far north Queensland, Australia. Renowned for its international reputation as a tourist destination, Cairns is a key urban centre relevant to the current federal government's vision to develop the vast geographical area of northern Australia. Using data obtained via surveys and follow-up explanatory interviews with a sample of practitioners working in the field, this article seeks to identify the potential ways in which the creative industries sector in Cairns might play a stronger role in relation to the vision for northern Australia. The findings point to the potential to explore and develop new opportunities and partnerships with other sectors of the Cairns economy, including education/training and tourism. In addition, evidence points to the need for strong leadership within the sector and in combination with other areas of the economy, so that the potential contribution of Cairns to the northern Australia vision might be strengthened.
Does Default Risk in Coupons Affect the Valuation of Corporate Bonds?: A Contingent Claims Model

The early work of Black and Scholes, and Merton, made the connection between conventional options and corporate liabilities. The standard textbooks now employ option-pricing arguments in discussing the valuation of stocks, bonds, convertible bonds and warrants; this discussion extends to the various features (such as call and sinking-fund features) that now are appended to these issues. The technique is to recognize that the value of a particular security derives from, or is contingent on, the value of the firm and other economic variables (such as the yield curve for government securities), and then apply the same valuation procedure that one would use to value a call option on some underlying common stock.
The Unrecognized Rotation of the Vestibular and Cochlear Nerves from the Labyrinth to the Brain Stem: Its Implications to Surgery of the Eighth Cranial Nerve

The cochlear and vestibular nerves rotate 90 degrees from the inner ear to the brain stem. Most of the rotation occurs within the internal auditory canal (IAC); only minimal rotation occurs in the cerebellopontine (CP) angle. At the labyrinthine end of the IAC, the cochlear nerve—which at first lies anterior to the inferior vestibular nerve (saccular nerve)—rapidly fuses with the inferior vestibular nerve. It then rotates to become inferior as the nerves leave the porus acousticus. The cochleovestibular (C-V) cleavage plane lies in a superior-inferior direction in the lateral IAC and rotates to become anterior-posterior in the CP angle. In 25% of patients in whom no C-V cleavage plane can be seen, it is not possible to completely transect all vestibular fibers. The surgical implications are that (1) the most complete vestibular neurectomy can be done only in the lateral IAC, (2) the cochlear and inferior vestibular nerves, because of their intimate association, should not be separated in the mid-IAC, in order to prevent damage to the cochlear nerve, and (3) to create a complete denervation of the vestibular labyrinth, only the posterior ampullary nerve along with the superior vestibular nerve should be transected.
Fluticasone propionate/formoterol for COPD management: a randomized controlled trial

Purpose To evaluate fluticasone propionate/formoterol (FP/FORM) in COPD. Patients and methods COPD patients with forced expiratory volume in 1 s (FEV1) ≤50% predicted and ≥1 moderate/severe COPD exacerbation in the last 12 months were randomized to FP/FORM 500/20 or 250/10 µg bid, or formoterol (FORM) 12 µg bid for 52 weeks. The primary outcome was the annualized rate of moderate/severe COPD exacerbations. Results In total, 1,765 patients were randomized. There were fewer discontinuations with FP/FORM 500/20 µg (20.6%) and 250/10 µg (24.0%) compared with FORM (26.1%). None of the two FP/FORM doses reduced the moderate/severe exacerbation rate versus FORM (rate ratios [RR]: 0.93; P≤0.402). There was a trend toward a lower moderate/severe exacerbation rate with FP/FORM 500/20 µg versus FORM in patients with ≥2 exacerbations in the preceding year (RR: 0.79; P=0.084). Pre- and post-dose FEV1 and forced vital capacity were greater with FP/FORM 500/20 µg versus FORM (P≤0.039). There was a trend toward a lower EXAcerbations of Chronic pulmonary disease Tool (EXACT) exacerbation rate with FP/FORM 500/20 µg versus FORM (RR: 0.87; P=0.077). There were more St George’s Respiratory Questionnaire for COPD (SGRQ-C) responders with FP/FORM 500/20 µg than FORM (odds ratios [OR] at weeks 6, 23 and 52 ≥1.28; P≤0.054). EXACT-respiratory symptoms total and breathlessness scores were lower with both FP/FORM 500/20 µg and 250/10 µg versus FORM (P≤0.066). Acute β2-agonist-induced effects and 24-hour Holter findings were similar for all treatments. Mean 24-hour urinary cortisol was similarly reduced with both FP/FORM doses. Radiologically confirmed pneumonia was seen in 2.4%, 3.2% and 1.5% of FP/FORM 500/20 µg, FP/FORM 250/10 µg and FORM-treated patients, respectively. Adverse events were otherwise similar across treatment groups. Conclusion FP/FORM did not reduce exacerbation rates versus FORM. Numerical benefits were observed with FP/FORM 500/20 µg versus FORM for secondary variables, including lung function, EXACT exacerbations, SGRQ-C and EXACT-respiratory symptoms total and breathlessness scores. Few efficacy differences were evident between FP/FORM 250/10 µg and FORM. Pneumonia was more frequent in FP/FORM-treated patients, although the absolute difference was low. Adverse events were otherwise similar between treatments.