Miracle-dz/UniFAR-FTUs huggingface dataset:
High Accuracy Prediction Framework for Predicting Defect Prone Software Components

In these days Predicting defect prone software components which are considered to be very prominent activity received with a good response from the individual. The enhanced feature in this paper is double verified framework with respect to all the proposed consideration and evaluation of the verified framework over the software defect prediction. Hence this framework allows the system followed by 1) unbiased along with that 2) examine the relation between the contending prediction systems. Perhaps the framework goes with the respective inclusion of 1) scheme evaluation, 2) defect prediction components and 3) verification of results. Certainly, with this scheme evaluation able to analyze the prediction performance of respective competing learning schemes with all the required historical data sets. Precisely the defect predictor capable of building models with respect to the evaluated learning scheme along with that it also predicts the software defects with all the data based on the constructed model. These defects can be re-verified by using Wei-bull model calculation and reducing the false positives.
Association of Maternal Weight Gain in Pregnancy With Offspring Obesity and Metabolic and Vascular Traits in Childhood

Background— We sought to examine the association of gestational weight gain (GWG) and prepregnancy weight with offspring adiposity and cardiovascular risk factors. Methods and Results— Data from 5154 (for adiposity and blood pressure) and 3457 (for blood assays) mother-offspring pairs from a UK prospective pregnancy cohort were used. Random-effects multilevel models were used to assess incremental GWG (median and range of repeat weight measures per woman: 10 [1, 17]). Women who exceeded the 2009 Institute of Medicine-recommended GWG were more likely to have offspring with greater body mass index, waist, fat mass, leptin, systolic blood pressure, C-reactive protein, and interleukin-6 levels and lower high-density lipoprotein cholesterol and apolipoprotein A1 levels. Children of women who gained less than the recommended amounts had lower levels of adiposity, but other cardiovascular risk factors tended to be similar in this group to those of offspring of women gaining recommended amounts. When examined in more detail, greater prepregnancy weight was associated with greater offspring adiposity and more adverse cardiovascular risk factors at age 9 years. GWG in early pregnancy (0 to 14 weeks) was positively associated with offspring adiposity across the entire distribution but strengthened in women gaining >500 g/wk. By contrast, between 14 and 36 weeks, GWG was only associated with offspring adiposity in women gaining >500 g/wk. GWG between 14 and 36 weeks was positively and linearly associated with adverse lipid and inflammatory profiles, with these associations largely mediated by the associations with offspring adiposity. Conclusions— Greater maternal prepregnancy weight and GWG up to 36 weeks of gestation are associated with greater offspring adiposity and adverse cardiovascular risk factors. Before any GWG recommendations are implemented, the balance of risks and benefits of attempts to control GWG for short- and long-term outcomes in mother and child should be ascertained.
Application of Percutaneous Cardiopulmonary Support for Cardiac Tamponade Following Blunt Chest Trauma: Two Case Reports

Since the advent of percutaneous cardiopulmonary support (PCPS), its application has been extended to massively injured patient. Cardiac injury following blunt chest trauma brings out high mortality and morbidity. In our cases, patients had high injury severity score by blunt trauma and presented sudden hemodynamic collapse in emergency room. We quickly detected cardiac tamponade by focused assessment with sonography for trauma and implemented PCPS. As PCPS established, their vital sign restored and then, they were transferred to the operation room (OR) securely. After all injured lesion repaired, PCPS weaned successfully in OR. They were discharged without complication on day 26 and 55, retrospectively.
Solute dispersion in channels with periodically varying apertures

We study solute dispersion in channels with periodically varying apertures. Based on an approximate analytical solution of the flow equation, we study the impact of the geometry and molecular diffusion on effective solute dispersion analytically using the method of local moments. We also study the problem numerically using a random walk particle tracking method. For transport in parallel shear flow, the effective dispersion coefficient is dependant on the square of the Peclet number. Here, when the fluctuation of the channel aperture becomes comparable with the channel width, the effective dispersion coefficients show a more complex dependence on the Peclet number and the pore geometry. We find that for a fixed flow rate, periodic fluctuations of the channel aperture can lead to both a decrease and an increase in effective dispersion.
Morphology of Foliar Trichomes of the Chinese Cork Oak Quercus variabilis by Electron Microscopy and Three-Dimensional Surface Profiling

Abstract Morphology of foliar trichomes was analyzed in Quercus variabilis by electron microscopy and three-dimensional surface profiling. Leaves from suppressed or dominant sprouts of the oak species were collected after a forest fire to unravel the effects of the disturbance factor on sprouting of the oak species. Scanning electron microscopy revealed two types of trichomes depending on the leaf surface. The trichomes on the adaxial surface were branched and constricted, and possessed a single row of thin-walled cells with a collapsed morphology (glandular branched uniseriate trichomes). Meanwhile, the trichomes on the abaxial surface were star-shaped, unfused with each other, and had 6 to 10 rays (nonglandular simple stellate trichomes). An apparent proliferation of trichomes was evident on the adaxial surface of the dominant sprouts. Uniseriate trichomes could be discernable as an elevation from the surface by white light scanning interferometry. By transmission electron microscopy, thin and convoluted cell wall, degenerated cytoplasm, and a single row of cells were characteristic of the trichomes on the adaxial surface. The thick cell walls of the mature trichomes on the abaxial surface represented the nonglandular nature. This is the first report on the morphological and ultrastructural characterization of foliar trichomes of the oak species.
Integrating research, clinical practice and translation: The singapore experience

We introduce the experiences of the Singapore ocular imaging team, iMED, in integrating image processing and computer-aided diagnosis research with clinical practice and knowledge, towards the development of ocular image processing technologies for clinical usage with potential impact. In this paper, we outline key areas of research with their corresponding image modalities, as well as providing a systematic introduction of the datasets used for validation.
Miniaturized Sensors and Sensing Systems for Liquid Media

One of the major research targets in our recent research has been the sensing of physical liquid parameters by means of miniaturized sensors. Such sensors and sen-sor systems can be utilized in applications, where liquids in industrial processes are monitored in order to maintain the quality of a process or the associated product. Due to the adverse properties commonly associated with chemical interfaces (lacking re-versibility, drift, etc.), we concentrate our research on physical parameters as indica-tors for the state of the liquid, in particularly density, viscosity (or more general rheological properties), and infrared absorption. The miniaturization of suitable sen-sor principles facilitates the implementation of these devices online. At the same time, scaling effects have to be taken into account, which, e.g., in case of viscosity sensors, lead to issues when it comes to applications in complex liquids such as suspensions. In our paper we provide an overview on our recent work discussing the device de-sign, the associated modeling, and the application of the devices. Keywords: Viscosity sensing, resonating sensors
Cdk5 and the non-catalytic arrest of the neuronal cell cycle

Cyclin-dependent kinase 5 (Cdk5) is a nontraditional Cdk that is primarily active in postmitotic neurons. An important core function of Cdk5 involves regulating the migration and maturation of embryonic post-mitotic neurons. Initially there is little evidence indicating a role for Cdk5 in normal cell cycle regulation. These development roles are on its kinase activity. Recent data from our lab, however, suggest that Cdk5 plays a crucial role as a cell cycle suppressor in normal post-mitotic neurons and neuronal cell lines. It performs this foundation in a kinase independent manner. Cdk5 normally found in both nucleus and cytoplasm, but it exits the nucleus in neurons risk to death in an AD patient’s brain. The shift in sub-cellular location is accompanied by cell cycle re-entry and neuronal death. This “new” function of Cdk5 raises cautions in the design of Cdk5-directed drugs for the therapy of neurodegenerative diseases.
SoTRAACE — Socio-technical risk-adaptable access control model

Within the necessary security requirements, access control measures are essential to provide adequate means to protect data from unauthorized accesses. However, current and traditional solutions are commonly based on predefined access policies and roles and are therefore inflexible by assuming uniform access control decisions through people's different type of devices, environments and situational conditions, and across enterprises, location and time. We live in an age of the mobile paradigm of anytime/anywhere access as the smartphone is the most ubiquitous device that people now hold. In this new age, access control models need to determine adaptable access decisions based on multiple factors aggregated at the moment of request and not just perform a predefined comparison of attributes. This paper presents a new access control model: SoTRAACE — Socio-Technical Risk-Adaptable Access Control Model. This model aggregates attributes from various domains to help performing a risk assessment that is balanced against the operational needs at the moment of each request, so to provide the most accurate and secure access decision. As a proof of concept, SoTRAACE is used to model and compare two different use case scenarios in the healthcare sector.
Brain Tumor Detection Based On Mathematical Analysis and Symmetry Information

Image segmentation some of the challenging issues on brain magnetic resonance image tumor segmentation caused by the weak correlation between magnetic resonance imaging intensity and anatomical meaning.With the objective of utilizing more meaningful information to improve brain tumor segmentation,an approach which employs bilateral symmetry information as an additional feature for segmentation is proposed.This is motivated by potential performance improvement in the general automatic brain tumor segmentation systems which are important for many medical and scientific applications.Brain Magnetic Resonance Imaging segmentation is a complex problem in the field of medical imaging despite various presented methods.MR image of human brain can be divided into several sub-regions especially soft tissues such as gray matter,white matter and cerebra spinal fluid.Although edge information is the main clue in image segmentation,it cannot get a better result in analysis the content of images without combining other information.Our goal is to detect the position and boundary of tumors automatically.Experiments were conducted on real pictures,and the results show that the algorithm is flexible and convenient.
Arabidopsis 3-Ketoacyl-Coenzyme A Synthase9 Is Involved in the Synthesis of Tetracosanoic Acids as Precursors of Cuticular Waxes, Suberins, Sphingolipids, and Phospholipids1[W]

KCS9 is involved in the elongation of C22 to C24 fatty acids, which are essential precursors for the biosynthesis of cuticular waxes, aliphatic suberins, and membrane lipids, including sphingolipids and phospholipids. Very-long-chain fatty acids (VLCFAs) with chain lengths from 20 to 34 carbons are involved in diverse biological functions such as membrane constituents, a surface barrier, and seed storage compounds. The first step in VLCFA biosynthesis is the condensation of two carbons to an acyl-coenzyme A, which is catalyzed by 3-ketoacyl-coenzyme A synthase (KCS). In this study, amino acid sequence homology and the messenger RNA expression patterns of 21 Arabidopsis (Arabidopsis thaliana) KCSs were compared. The in planta role of the KCS9 gene, showing higher expression in stem epidermal peels than in stems, was further investigated. The KCS9 gene was ubiquitously expressed in various organs and tissues, including roots, leaves, and stems, including epidermis, silique walls, sepals, the upper portion of the styles, and seed coats, but not in developing embryos. The fluorescent signals of the KCS9::enhanced yellow fluorescent protein construct were merged with those of BrFAD2::monomeric red fluorescent protein, which is an endoplasmic reticulum marker in tobacco (Nicotiana benthamiana) epidermal cells. The kcs9 knockout mutants exhibited a significant reduction in C24 VLCFAs but an accumulation of C20 and C22 VLCFAs in the analysis of membrane and surface lipids. The mutant phenotypes were rescued by the expression of KCS9 under the control of the cauliflower mosaic virus 35S promoter. Taken together, these data demonstrate that KCS9 is involved in the elongation of C22 to C24 fatty acids, which are essential precursors for the biosynthesis of cuticular waxes, aliphatic suberins, and membrane lipids, including sphingolipids and phospholipids. Finally, possible roles of unidentified KCSs are discussed by combining genetic study results and gene expression data from multiple Arabidopsis KCSs.
Virtual Embodiment of White People in a Black Virtual Body Leads to a Sustained Reduction in Their Implicit Racial Bias

Virtual reality can be used to visually substitute a person's body by a life-sized virtual one. Such embodiment results in a perceptual illusion of body ownership over the virtual body (VB). Previous research has shown that the form of the VB can influence implicit attitudes. In particular, embodying White people in a Black virtual body is associated with an immediate decrease in their implicit racial bias against Black people. We tested whether the reduction in implicit bias lasts for at least 1 week and whether it is enhanced by multiple exposures. Two experiments were carried out with a total of 90 female participants where the virtual body was either Black or White. Participants were required to follow a virtual Tai Chi teacher who was either Asian or European Caucasian. Each participant had 1, 2, or 3 exposures separated by days. Implicit racial bias was measured 1 week before their first exposure and 1 week after their last. The results show that implicit bias decreased more for those with the Black virtual body than the White. There was also some evidence of a general decrease in bias independently of body type for which possible explanations are put forward.
Hard Targets: Theory and Evidence on Suicide Attacks*

Who chooses suicide attacks? Though rebels typically target poor countries, suicide attacks are just as likely to target rich democracies. Though many groups have grievances, suicide attacks are favored by the radical religious. Though rebels often kill coreligionists, they seldom use suicide attacks to do so. We model the choice of tactics by rebels, bearing in mind that a successful suicide attack imposes the ultimate cost on the attacker and the organization. We first ask what a suicide attacker would have to believe to be deemed rational. We then embed the attacker and other operatives in a club good model which emphasizes the function of voluntary religious organizations as providers of benign local public goods. The sacrifices which these groups demand solve a free-rider problem in the cooperative production of public goods. These sacrifices make clubs well suited for organizing suicide attacks, a tactic in which defection by operatives (including the attacker) endangers the entire organization. The model also analyzes the choice of suicide attacks as a tactic, predicting that suicide will be used when targets are well protected and when damage is great. Those predictions are consistent with the patterns described above. The model has testable implications for tactic choice of terrorists and for damage achieved by different types of terrorists, which we find to be consistent with the data. *We thank Eva Meyersson Milgrom for organizing the Stanford suicide terrorism project and for her foresight in matchmaking this collaboration. We also thank Barak Bouks for research assistance. This version benefitted from discussions with
Prosocial Attitude Modulates Muscle Activity in a Simple Coordination Game

Social and economic literature generally considers that the relevance of property rights in human interaction arises from an explicit cognitive processes, which emerge with social competence. In the present work we aimed at investigating whether the arbitrary allocation of property rights automatically affects individuals' behavior, within a context with no visual and verbal interaction and removed from any perspective‐taking activity. To this purpose we submitted twelve pairs of participants to a simple motor coordination game while recording the electromyographic activity of the muscle mainly involved in the task. By using the answers to a questionnaire to measure the participants' degree of sociability, the correlation between muscle involvement and prosocial attitude revealed that low prosocial individuals, only, significantly changed their motor behavior in response to a reallocation of property rights. Results are discussed in relation to the endowment effect, a puzzling phenomenon observed in actual behavior, that had challenged the traditional assumption of rationality in many behavioral models. 2 INTRODUCTION In actual societies the most part of collective welfare is generated through market transactions and
Binary and Millisecond Pulsars

We review the main properties, demographics and applications of binary and millisecond radio pulsars. Our knowledge of these exciting objects has greatly increased in recent years, mainly due to successful surveys which have brought the known pulsar population to over 1700. There are now 80 binary and millisecond pulsars associated with the disk of our Galaxy, and a further 103 pulsars in 24 of the Galactic globular clusters. Recent highlights have been the discovery of the first ever double pulsar system and a recent flurry of discoveries in globular clusters, in particular Terzan 5.
Three-Dimensional Microfabrication System for Scaffolds in Tissue Engineering

Understanding chondrocyte behavior inside complex, three-dimensional environments with controlled patterning of geometrical factors would provide significant insights into the basic biology of tissue regenerations. One of the fundamental limitations in studying such behavior has been the inability to fabricate controlled 3D structures. To overcome this problem, we have developed a three-dimensional microfabrication system. This system allows fabrication of predesigned internal architectures and pore size by stacking up the photopolymerized materials. Photopolymer SL5180 was used as the 3D microfabricated scaffolds. The results demonstrate that controllable and reproducible inner-architecture can be fabricated. Chondrocytes from human nasal septum were cultured in 3D scaffolds for cell adhesion behavior. Such 3D scaffolds might provide effective key factors to study cell behavior in complex environments and could eventually lead to optimum design of scaffolds in various tissue regenerations such as cartilage, bone, etc. in a near future.
Unique Profile of Ordered Arrangements of Repetitive Elements in the C57BL/6J Mouse Genome Implicating Their Functional Roles

The entirety of all protein coding sequences is reported to represent a small fraction (∼2%) of the mouse and human genomes; the vast majority of the rest of the genome is presumed to be repetitive elements (REs). In this study, the C57BL/6J mouse reference genome was subjected to an unbiased RE mining to establish a whole-genome profile of RE occurrence and arrangement. The C57BL/6J mouse genome was fragmented into an initial set of 5,321 units of 0.5 Mb, and surveyed for REs using unbiased self-alignment and dot-matrix protocols. The survey revealed that individual chromosomes had unique profiles of RE arrangement structures, named RE arrays. The RE populations in certain genomic regions were arranged into various forms of complexly organized structures using combinations of direct and/or inverse repeats. Some of these RE arrays spanned stretches of over 2 Mb, which may contribute to the structural configuration of the respective genomic regions. There were substantial differences in RE density among the 21 chromosomes, with chromosome Y being the most densely populated. In addition, the RE array population in the mouse chromosomes X and Y was substantially different from those of the reference human chromosomes. Conversion of the dot-matrix data pertaining to a tandem 13-repeat structure within the Ch7.032 genome unit into a line map of known REs revealed a repeat unit of ∼11.3 Kb as a mosaic of six different RE types. The data obtained from this study allowed for a comprehensive RE profiling, including the establishment of a library of RE arrays, of the reference mouse genome. Some of these RE arrays may participate in a spectrum of normal and disease biology that are specific for mice.
Effects of a tumour promoter, 12-0-tetradecanoyl-phorbol-13-acetate (TPA), on expression of differentiated phenotype in the chick retinal pigmented epithelial cells and on their interactions with the native basement membrane and with artificial substrata.

Chick retinal pigmented epithelial (RPE) cells grown in vitro on basement membrane matrices from the Engelbreth-Holm-Swarm tumour (BM-matrigel) do not spread, and they maintain their differentiated phenotype, most notably the heavy pigmentation. Maintenance of the differentiated phenotype by RPE cells on BM-matrigel is promoted not only by the biochemical composition of the gel but also by its mechanical properties, i.e., its low rigidity prevents cell spreading. In this report, RPE cells on BM-matrigel were treated with 12-O-tetradecanoyl-phorbol-13-acetate (TPA) to promote the transformed phenotype and diminish cell traction. In contrast to most cell types TPA treatment induced RPE cells to increase their spread area. TPA promoted RPE cell spreading on BM-matrigel and changed the spatial organization of actin and actin-associated proteins in the cytoskeleton-ECM linkage complexes, uncoupling actin from its extracellular counterpart. TPA did not affect other components of the cytoskeleton in RPE cells. TPA also affected labile adhesions i.e., focal contacts and adherens junctions in statu nascendi, but preformed, stable adherens junctions were resistant to TPA. TPA enhanced proliferation, blocked melanogenesis and thus inhibited differentiation of RPE cells grown on either artificial substrata or their natural basement membrane.