Miracle-dz/UniFAR-FTUs huggingface dataset:
: Automatic Categorization of SQL-Query-Results

Search queries on database-systems typically return too many results many of them irrelevant to the user. This phenomenon is commonly referred to as information-overload, as the user expends a huge amount of effort sifting through the result-set looking for interesting results. This article reviews two approaches to tackling this problem. Both approaches are based on categorization; the query results are grouped into categories. These categories are then organized into a hierarchy forming a navigation-tree. The user traverses this tree, top-down, and chooses to view the results upon reaching the desired category.
Probiotics and immune health

Purpose of review The beneficial effects of probiotics have been demonstrated in many diseases. One of the major mechanisms of probiotic action is through the regulation of host immune response. This review highlights the recent scientific research findings that advance our understanding of probiotic regulation of the host immune response with potential application for disease prevention and treatment. Recent findings Probiotic genomic and proteomic studies have identified several genes and specific compounds derived from probiotics, which mediate immunoregulatory effects. Studies regarding the biological consequences of probiotics in host immunity suggested that they regulate the functions of systemic and mucosal immune cells and intestinal epithelial cells. Thus, probiotics showed therapeutic potential for diseases, including several immune response-related diseases, such as allergy, eczema, viral infection, and potentiating vaccination responses. Summary Probiotics may provide novel approaches for both disease prevention and treatment. However, the results of clinical studies regarding probiotic application are preliminary and require further confirmation.
Combining pairwise sequence similarity and support vector machines for remote protein homology detection

One key element in understanding the molecular machinery of the cell is to understand the meaning, or function, of each protein encoded in the genome. A very successful means of inferring the function of a previously unannotated protein is via sequence similarity with one or more proteins whose functions are already known. Currently, one of the most powerful such homology detection methods is the SVM-Fisher method of Jaakkola, Diekhans and Haussler (ISMB 2000). This method combines a generative, profile hidden Markov model (HMM) with a discriminative classification algorithm known as a support vector machine (SVM). The current work presents an alternative method for SVM-based protein classification. The method, SVM-pairwise, uses a pairwise sequence similarity algorithm such as Smith-Waterman in place of the HMM in the SVM-Fisher method. The resulting algorithm, when tested on its ability to recognize previously unseen families from the SCOP database, yields significantly better remote protein homology detection than SVM-Fisher, profile HMMs and PSI-BLAST.
Place and Placelessness Revisited

relationship between transport decisions and the Coast’s settlement patterns, Chapter four outlines the missed opportunities and car-centric thinking that have resulted in extreme car dependency (88% of all trips) on the coast. As the authors point out, this is a startling figure for a city so orientated towards tourism and an outdoor lifestyle (p. 45). This is not a theoretical account of the city and besides sporadic references to urbanisation, risk and the city, path dependent development and innovation in development, the text makes very few attempts to theorise urban development beyond the case study. While this might frustrate academic readers, I see one potential advantage. By taking the coast for what it is and not cloaking it a priori theorisations of urban development, the author’s avoid Massey’s critique of much city scholarship: that repetitive and insistent mantra that reads globalization and neoliberalism as discourses of enclosure and inevitability (2005, p. 161). As a result, even as the Coast prepares to host the Commonwealth Games in 2018 (another sign of its emerging status as a world city) this text tells stories of change, openness and opportunities (taken and lost), in other words, it portrays the Coast as a city in the making. This is thinking with the city. The book’s main contribution is arguably to the residents of city of Gold Coast itself, who stand to benefit most from decision-makers taking seriously future development on the Coast. Through its unwavering gaze, it lays bare the city with all its oddities and failures and there are many: the unfailing courting of the tourist dollar, the serious lack of planning interventions in the early development of the city and ad hoc nature of development, on-going reinvention of the city’s identity, the failure throughout the city’s history to pay attention to and prioritize the needs of the city’s residents over tourists, the parochial and development-focused view of the men (they were all men) who have been in positions of power. Yet I came away from this book with affection for the Coast. For all its failings, it is a fascinating city. Disclosure: I grew up on the Coast so my reading of this text was personal as much as it was academic. I am also a graduate of Griffith University’s School of Environment where many of the book’s authors are employed and I was taught by several of the authors during my undergraduate studies.
Computational and implementation strategies for smart visual sensors in automotive applications

This paper reports on the status of ongoing research aimed at the development of analog VLSI sensory modules with embedded dynamic perceptual processing. A schematic organisation of vision-guided behaviour and a mathematical model for a reaction and diffusion system are presented. A basic co-operative block (the Peceptual Engine) is introduced and its practical realisation, performance and limitations are described. Its application in the hardware implementation of an important class of perceptual problems, such as stereo disparity estimation and motion analysis, is considered. The main assets of the Perceptual Engine are seen as its capability of providing rapid reactions to sensorial data and its robustness. (A) For the covering abstract see ITRD E106152.
Reviewer's report Title: Exploring reasons for non-participation and withdrawal from a randomised controlled trial of telehealth and telecare in England: a qualitative study

The article, Exploring Reasons for Non-Participation and Withdrawal from a Randomized Controlled Trial of Telehealth and Telecare in England: A Qualitative Study, is well written and makes an important contribution to our understanding of a persistent barrier to healthcare. Although it is publishable in its present form, I hope the authors will consider several proposed changes that would enhance the focus and clarity of the article.
Bodyweight QTL on mouse chromosomes 4 and 11 by selective genotyping: regression v. maximum likelihood

Two quantitative trait loci (QTL) for mouse bodyweight have previously been reported on mouse chromosomes (MMU) 4 and 11 from crosses of a highly fecund and large mouse strain, Inbred Quackenbush-Swiss 5 (QSi5) and C57Bl/6J. QSi5 has now been crossed with CBA/CaH to produce 1128 F2 mice to confirm the existence and effect of these QTL. In total, 226 mice from the upper and lower deciles for bodyweight were genotyped using 12 microsatellite markers covering MMU4 and MMU11. Regression and maximum likelihood based interval mapping by either including all mice (ungenotyped mice were treated as having missing genotypes) or including only selectively genotyped mice in the analyses were used to estimate the positions and effects of the QTL. The results confirmed the existence and effects of both QTL. Although all methods estimated the same QTL positions, the QTL effects were overestimated compared with the estimates using a suggested method (maximum likelihood by including all mice in the analysis). However, the overestimated QTL effects could be mathematically corrected. Since the confidence intervals of both QTL are still too large for positional cloning, an advanced intercross line is being bred for finely mapping these bodyweight QTL.
Primary Pulmonary Lymphoma and Synchronous Cecal Adenocarcinoma: A Rare Occurrence

In the era of extensive imaging and increasing indications for performing PET-CT scans, the recognition of synchronous tumors may be greater than before. However, the majority of these tumors are seen to occur in the same organ system, likely because of sharing similar pathogenic mechanisms. Synchronous lung cancers of similar or differing histologies have been reported. Primary pulmonary lymphoma, which is a rare form of non-Hodgkin’s lymphoma, has also been seen with a synchronous primary lung cancer. However, we report a case of a 56-year-old male diagnosed with primary pulmonary lymphoma and on PET-CT imaging, found to have a cecal lesion, the biopsy of which showed adenocarcinoma. We discuss the incidence of the co-existence of multiple tumors, the pathogenic mechanisms involved, and approaches to the management of these rare clinical scenarios.
Reliability and validity evidence of multiple balance assessments in athletes with a concussion.

CONTEXT An estimated 300 000 sport-related concussion injuries occur in the United States annually. Approximately 30% of individuals with concussions experience balance disturbances. Common methods of balance assessment include the Clinical Test of Sensory Organization and Balance (CTSIB), the Sensory Organization Test (SOT), the Balance Error Scoring System (BESS), and the Romberg test; however, the National Collegiate Athletic Association recommended the Wii Fit as an alternative measure of balance in athletes with a concussion. A central concern regarding the implementation of the Wii Fit is whether it is reliable and valid for measuring balance disturbance in athletes with concussion. OBJECTIVE To examine the reliability and validity evidence for the CTSIB, SOT, BESS, Romberg test, and Wii Fit for detecting balance disturbance in athletes with a concussion. DATA SOURCES Literature considered for review included publications with reliability and validity data for the assessments of balance (CTSIB, SOT, BESS, Romberg test, and Wii Fit) from PubMed, PsycINFO, and CINAHL. DATA EXTRACTION We identified 63 relevant articles for consideration in the review. Of the 63 articles, 28 were considered appropriate for inclusion and 35 were excluded. DATA SYNTHESIS No current reliability or validity information supports the use of the CTSIB, SOT, Romberg test, or Wii Fit for balance assessment in athletes with a concussion. The BESS demonstrated moderate to high reliability (interclass correlation coefficient = 0.87) and low to moderate validity (sensitivity = 34%, specificity = 87%). However, the Romberg test and Wii Fit have been shown to be reliable tools in the assessment of balance in Parkinson patients. CONCLUSIONS The BESS can evaluate balance problems after a concussion. However, it lacks the ability to detect balance problems after the third day of recovery. Further investigation is needed to establish the use of the CTSIB, SOT, Romberg test, and Wii Fit for assessing balance in athletes with concussions.
Growth and metastasis of tumor in organ culture

SYSTEM THAT WOIJLD PROMOTE THE IN A vitro growth of malignant tumors in their normal solid configuration would be an invaluable aid in the study of factors influencing metastases, cancer chemotherapy, and relationships between tumor and host tissue. Such a system would also open studies of functioning tumors and their relationship with circulating stimulatory substances. A system for the perfusion of isolated, small organs was developed in this laboratory as a by-product of an investigation originally designed to test the efficacy of hemoglobin-plasma solutions as a blood substitute for prolonged extracorporeal perfusion. Crystalline hemoglobin in plasma or serum was perfused through isolated organs, (thyroid, kidney, intestine) for several days in a small apparatus using a 50-cc. disk
Are We Ready to Go Large-scale? - Challenges in the Deployment and Maintenance of Heterogeneous Networks of Cooperating Objects

The world is changing at an incredible pace. An enormous amount of data is being generated continuously everywhere at a rate faster than ever before, leaving us with the challenge of making sense out of it at the right time and the right place. With concepts such as the Internet of Things, Cyber-Physical-Systems, Cooperating Objects and Smart Cities, things are only going to get worse. But are we ready to go large-scale? In this talk, we will deal with the main challenges and present some possible answers to the question of how to deploy, maintain and use a network composed of millions, if not billions, of sensors, smart phones and, in general, devices that continuously gather, process and send data into our lives. Without the right technology, we might become slaves of our own technology instead of being on top of it. Are we ready for the challenge?
Linguistic and Statistical Traits Characterising Plagiarism

This paper investigates the problem of distinguishing between original and rewritten text materials, with focus on the application of plagiarism detection. The hypothesis is that original texts and rewritten texts exhibit significant and measurable differences, and that these can be captured through statistical and linguistic indicators. We propose and analyse a number of these indicators (including language models, syntactic trees, etc.) using machine learning algorithms in two main settings: (i) the classification of individual text segments as original or rewritten, and (ii) the ranking of two or more versions of a text segment according to their “originality”, thus rendering the rewriting direction. Different from standard plagiarism detection approaches, our settings do not involve comparisons between supposedly rewritten text and (a large number of) original texts. Instead, our work focuses on the sub-problem of finding segments that exhibit rewriting traits. Identifying such segments has a number of potential applications, from a first-stage filtering for standard plagiarism detection approaches, to intrinsic plagiarism detection and authorship identification. The corpus used in the experiments was extracted from the PAN-PC-10 plagiarism detection task, with two subsets containing manually and artificially generated plagiarism cases. The accuracies achieved are well above a by chance baseline across datasets and settings, with the statistical indicators being particularly effective.
Comovements in the Prices of Securities Issued by Large Complex Financial Institutions

In recent years, mergers, acquisitions and organic growth have meant that some of the largest and most complex financial groups have come to transcend national boundaries and traditionally defined business lines. As a result, they have become a potential channel for the cross-border and crossmarket transmission of financial shocks. This paper analyses the degree of comovement in the prices of securities issued by a selected group of large complex financial institutions (LCFIs), and assesses the extent to which movements in the prices of these securities are driven by common factors. A relatively high degree of commonality is found for most LCFIs (compared to a control group of nonfinancials), although there are still noticeable divisions between sub-groups of LCFIs, both according to geography and primary business-line.
On the Acceptability of Arguments in Preference-based Argumentation

Argumentation is a promising model for reasoning with uncertain and inconsistent knowledge. The key concept of acceptability enables to differentiate arguments and defeaters: The certainty of a proposition can then be evaluated through the most acceptable arguments for that proposition. In this paper, we investigate different complementary points of view: an acceptability based on the existence of direct defeaters and an acceptability based on the existence of defenders. Pursuing previous work on preference-based argumentation principles, we enforce both points of view by taking into account preference orderings for comparing arguments. Our approach is illustrated in the context of reasoning with stratified knowledge bases.
Real-time per-cycle energy consumption measurement of digital systems

A real-time per-clock-cycle energy measurement technique is presented for power analysis and the reduction of energy consumption of synchronous state machines. This technique guarantees accuracy with a sampling rate of twice the clock frequency under spiky current draw conditions common in digital systems. In addition, it acquires the energy consumption profile in real-time, and therefore does not require repeated operation of the target system.
OPC-67683, a Nitro-Dihydro-Imidazooxazole Derivative with Promising Action against Tuberculosis In Vitro and In Mice

Background Tuberculosis (TB) is still a leading cause of death worldwide. Almost a third of the world's population is infected with TB bacilli, and each year approximately 8 million people develop active TB and 2 million die as a result. Today's TB treatment, which dates back to the 1970s, is long and burdensome, requiring at least 6 mo of multidrug chemotherapy. The situation is further compounded by the emergence of multidrug-resistant TB (MDR-TB) and by the infection's lethal synergy with HIV/AIDS. Global health and philanthropic organizations are now pleading for new drug interventions that can address these unmet needs in TB treatment. Methods and Findings Here we report OPC-67683, a nitro-dihydro-imidazooxazole derivative that was screened to help combat the unmet needs in TB treatment. The compound is a mycolic acid biosynthesis inhibitor found to be free of mutagenicity and to possess highly potent activity against TB, including MDR-TB, as shown by its exceptionally low minimum inhibitory concentration (MIC) range of 0.006–0.024 μg/ml in vitro and highly effective therapeutic activity at low doses in vivo. Additionally, the results of the post-antibiotic effect of OPC-67683 on intracellular Mycobacterium tuberculosis showed the agent to be highly and dose-dependently active also against intracellular M. tuberculosis H37Rv after a 4-h pulsed exposure, and this activity at a concentration of 0.1 μg/ml was similar to that of the first-line drug rifampicin (RFP) at a concentration of 3 μg/ml. The combination of OPC-67683 with RFP and pyrazinamide (PZA) exhibited a remarkably quicker eradication (by at least 2 mo) of viable TB bacilli in the lung in comparison with the standard regimen consisting of RFP, isoniazid (INH), ethambutol (EB), and PZA. Furthermore, OPC-67683 was not affected by nor did it affect the activity of liver microsome enzymes, suggesting the possibility for OPC-67683 to be used in combination with drugs, including anti-retrovirals, that induce or are metabolized by cytochrome P450 enzymes. Conclusions We concluded that based on these properties OPC-67683 has the potential to be used as a TB drug to help combat the unmet needs in TB treatment.
Subduction d'une dorsale océanique active : géologie des ophiolites de Taitao (point triple du Chili)

La peninsule de taitao (4546's-74w) est situee a 50 km au sud du point triple du chili. Elle a ete a deux reprises le lieu de la subduction de la ride du chili sous la marge continentale, vers 5 ma et 3 ma. A la suite de l'echantillonnage de terrain, des analyses structurales et petro-geochimiques ont precise les liens entre la subduction de la dorsale et la mise en place de l'ophiolite et du magmatisme associe. Nous montrons que l'ophiolite de taitao est incomplete car les deux unites volcano-sedimentaires decrites ne constituent pas sa couverture. La premiere unite plio-pleistocene repose en discordance sur la marge. Elle s'est deposee en milieu marin peu profond durant la subduction de la ride du chili. La seconde unite se distingue par un metamorphisme dans le facies des schistes verts. Les laves des deux unites comprennent des basaltes de ride medio-oceanique (morb), des andesites et des dacites comparables en composition a des roches d'arc volcanique. Les caracteristiques chimiques de ces roches s'expliquent par un processus de contamination crustale de basaltes de type morb. Les suites volcaniques sont donc considerees comme le produit de l'emission de morb par la dorsale enfouie a de faibles profondeurs sous la marge. Pendant leur remontee a travers la croute continentale, ces magmas ont ete contamines a des degres variables. L'ophiolite est vue comme une section de croute oceanique detachee de la plaque plongeante lors de la collision ride-fosse puis incorporee a la marge, avant ou pendant le magmatisme anormalement proche de la fosse
Simplified, data-driven, errorable car-following model to predict the safety effects of distracted driving

An errorable car-following model is presented in this paper. The model was developed to predict the situational risk associated with distracted driving. To obtain longitudinal driving patterns, this paper analyzed and synthesized the NGSIM naturalistic driver and traffic database to identify essential driver behavior and characteristics. NGSIM data was modified according to data from cognitive psychology concepts to examine the probabilistic nature of distracted driving due to internal vehicle distractions. The errorable microscopic car-following model was developed and validated, which can be fully integrated with the naturalistic data and incorporate the probabilities of driver distraction. The proposed model predicts that distracted driving in congested conditions can result in crash rates 3.25 times that of normal driving conditions.
The male germline of angiosperms: repertoire of an inconspicuous but important cell lineage

The male germline of flowering plants constitutes a specialized lineage of diminutive cells initiated by an asymmetric division of the initial microspore cell that sequesters the generative cell from the pollen vegetative cell. The generative cell subsequently divides to form the two male gametes (non-motile sperm cells) that fuse with the two female gametophyte target cells (egg and central cells) to form the zygote and endosperm. Although these male gametes can be as little as 1/800th of the volume of their female counterpart, they encode a highly distinctive and rich transcriptome, translate proteins, and display a novel suite of gamete-distinctive control elements that create a unique chromatin environment in the male lineage. Sperm-expressed transcripts also include a high proportion of transposable element-related sequences that may be targets of non-coding RNA including miRNA and silencing elements from peripheral cells. The number of sperm-encoded transcripts is somewhat fewer than the number present in the egg cell, but are remarkably distinct compared to other cell types according to principal component and other analyses. The molecular role of the male germ lineage cells is just beginning to be understood and appears more complex than originally anticipated.
A cache-based parallel genetic algorithm for the BDD variable ordering problem

Binary Decision Diagrams (BDDs) have proved to be a powerful representation for Boolean functions. Particularly, they are a very useful data structure for the symbolic model checking of digital circuits and other finite state systems, as well as other problems. Nevertheless, the size of the BDD representation of these functions is highly dependent on the order of the function arguments, also called variables, and to find such good ordering is an NP-Complete problem. Many heuristics have been proposed to solve this problem, as our Parallel Genetic Algorithm presented in [4], where we got excellent results in terms of parallelization. Now, we present a new version of our algorithm, this time with a cache system, together with experimental results. Keywords— binary decision diagrams (BDDs), genetic algorithms, parallel processing, symbolic model checking.