Miracle-dz/UniFAR-FTUs huggingface dataset:
Contemporary Management of Postcatheterization Pseudoaneurysms

A pseudoaneurysm (PSA) is a contained rupture; there is a disruption in all 3 layers of the arterial wall (Figure 1). PSAs may occur under 4 circumstances: (1) after catheterization (Figure 2); (2) at the site of native artery and synthetic graft anastomosis (eg, aortofemoral bypass graft); (3) trauma; and (4) infection (eg, mycotic PSA) (Figure 3). This review will focus on PSAs that occur after cardiac and peripheral endovascular procedures. PSAs occur when an arterial puncture site does not adequately seal. Pulsatile blood tracks into the perivascular space and is contained by the perivascular structures, which then take on the appearance of a sac. Hematoma and the surrounding tissue form the wall of the PSA. Figure 1. Artist’s rendition of a postcatheterization PSA with proper placement of the needle for thrombin injection. There is a disruption in all 3 layers of the arterial wall. In essence, this represents a contained rupture. Figure 2. Arteriogram that demonstrates an axillary artery PSA after a diagnostic arteriographic procedure. Note the disruption in the vessel wall (white arrow) and the larger PSA sac (black arrow). Figure 3. Ultrasound of a spontaneous PSA in the left brachial artery. Note the absence of a tract. The PSA chamber is directly connected to the brachial artery. This type of PSA must be treated surgically. This patient had infective endocarditis. Postcatheterization PSA is one of the most common vascular complications of cardiac and peripheral angiographic procedures. The incidence of PSA after diagnostic catheterization ranges from 0.05% to 2%. 1 When coronary or peripheral intervention is performed, the incidence increases to 2% to 6%. In 1 series where diagnostic ultrasound was performed on 536 consecutive patients who underwent catheterization, the incidence of PSA was 7.7%, with 83% of the PSAs associated with interventional procedures.2 Despite a low …
Managing mood disorders in patients attending pulmonary rehabilitation clinics

Background There is good evidence for the positive benefits of pulmonary rehabilitation (PR) in the prevention of hospital admissions, lower mortality, and improved health-related quality of life. There is also increasing evidence about the impact of PR on mental health and, in particular, mood disorders. We aimed to identify how depression in chronic obstructive pulmonary disease (COPD) patients in Victoria, Australia, is being managed in PR, to identify the prevalence of depressive symptoms among COPD patients who attend PR, and to determine whether patients with depressive symptoms or anxiety symptoms dropped out of PR early. Method Of 61 PR clinics, 44 were invited and 22 agreed to participate. Telephone interviews were conducted to see how depression and anxiety in COPD patients were being recognized and managed in these clinics. A total of 294 questionnaires were distributed to patients by clinic coordinators to determine the prevalence of anxiety/depression, as measured by the Hospital Anxiety and Depression Scale. Coordinators were contacted to provide information on whether respondents dropped out of rehabilitation early or continued with their treatment at 2–4 months post program. Results Seven clinics were not aware of local guidelines on assessment/treatment/management of mood. Four clinics did not use any screening tools or other aids in the recognition and management of depression and/or anxiety. Overall, eight clinics participating in this study requested advice on suitable screening tools. The patient survey indicated that the mean depression score on the Hospital Anxiety and Depression Scale was 5.0 (standard deviation 3.0, range 1–13). The mean anxiety score was 5.5 (standard deviation 3.4, range 0–18). There was no evidence of a link between failure to complete rehabilitation and depression or anxiety scores, as only three of 105 patients failed to complete their rehabilitation. Discussion: Awareness of management guidelines for depression and anxiety in COPD patients was variable across the clinics recruited into our study. We found no link between compliance with rehabilitation and depression, but our sample had limitations. Conclusion Future research needs to investigate how best to encourage more use of available guidelines regarding integrating psychological and psychosocial support to supplement the exercise and education that are currently offered routinely by all PR clinics studied in Victoria, Australia.
Special FocuS: advanced FeedStockS For advanced bioFuelS

Untreated biomass has a wide range of moisture content (25–60%), large particle-size distribution depending upon drying and grinding/chipping conditions, low energy density (8–14 MJ/kg), and low bulk density (60–100 kg/m) coupled with fibrous interlocking particles that tend to resist flow. These biomass characteristics introduce challenges for handling and conversion processes. Ensuring that biomass feedstock materials consistently meet established specifications appears critical for optimizing conversion processes [1]. Thermochemical processes include a wide range of technologies to break down lignocellulosic matter at elevated temperatures under oxygen-limited conditions to control or prevent the oxidation reactions that are characteristic of complete combustion [2]. Gasification carefully controls the amount of oxygen present to produce primarily syngas (which consists mostly of CO, hydrogen, water vapor and CH 4 ) and is generally considered the most complete form of thermochemical conversion in the Impact of thermal pretreatment on the fast pyrolysis conversion of southern pine
Three simultaneous speech recognition by integration of active audition and face recognition for humanoid

This paper addresseslistening to three simultaneous talkers by a humanoidwith two microphones. In such situations, sound separation and automatic speech recognition (ASR) of the separated speech are difﬁcult, becausethe number of simultaneous talkers exceedsthat of its microphones, the signal-to-noise ratio is quite low (around -3 dB) and noise is not stable due to interfering voices. Humanoid audition system consistsof sound separation, face recognition and ASR. Sound sources are separated by an active direction-pass ﬁlter (ADPF), which extracts sounds from a speciﬁeddirection in real-time. Since features of sounds separated by ADPF vary according to the sound direction, ASR uses multiple direction-and speaker-dependent acoustic models. The system integrates ASR results by using the sound direction and speaker information by face recognition as well as conﬁdence measure of ASR results to select the best one. The resulting system improves word recognition rates against three simultaneous utterances.
Enhanced performance of microfluidic soft pressure sensors with embedded solid microspheres

The cross-sectional geometry of an embedded microchannel influences the electromechanical response of a soft microfluidic sensor to applied surface pressure. When a pressure is exerted on the surface of the sensor deforming the soft structure, the cross-sectional area of the embedded channel filled with a conductive fluid decreases, increasing the channel’s electrical resistance. This electromechanical coupling can be tuned by adding solid microspheres into the channel. In order to determine the influence of microspheres, we use both analytic and computational methods to predict the pressure responses of soft microfluidic sensors with two different channel cross-sections: a square and an equilateral triangular. The analytical models were derived from contact mechanics in which microspheres were regarded as spherical indenters, and finite element analysis (FEA) was used for simulation. For experimental validation, sensor samples with the two different channel cross-sections were prepared and tested. For comparison, the sensor samples were tested both with and without microspheres. All three results from the analytical models, the FEA simulations, and the experiments showed reasonable agreement confirming that the multi-material soft structure significantly improved its pressure response in terms of both linearity and sensitivity. The embedded solid particles enhanced the performance of soft sensors while maintaining their flexible and stretchable mechanical characteristic. We also provide analytical and experimental analyses of hysteresis of microfluidic soft sensors considering a resistive force to the shape recovery of the polymer structure by the embedded viscous fluid.
Predicting and Adapting to Poor Speech Recognition in a Spoken Dialogue System

Spoken dialogue system performance can vary widely for different users, as well for the same user during different dialogues. This paper presents the design and evaluation of an adaptive version of TOOT, a spoken dialogue system for retrieving online train schedules. Adaptive TOOT predicts whether a user is having speech recognition problems as a particular dialogue progresses, and automatically adapts its dialogue strategies based on its predictions. An empirical evaluation of the system demonstrates the utility of the approach.
A Comparative Study on Processing, Mechanical Properties, Thermo-oxidative Aging, Water Absorption, and Morphology of Rice Husk Powder and Silica Fillers in Polystyrene/Styrene Butadiene Rubber Blends

Rice husk powder (RHP) and silica-filled polystyrene (PS)/styrene butadiene rubber (SBR) composites were prepared by using the laboratory size internal mixer (Brabender Plasti-corder). The torque development, morphology, and mechanical properties such as tensile strength, elongation at break, Young modulus, and impact strength were studied. Water absorption and the effect of thermo-oxidative aging on tensile properties of composites were also examined. Filler loading and filler type influence the processibility of the composites in which RHP offers better processing advantage over silica. Tensile strength reduces with increasing filler loading for both RHP and silica composites. However, at 15 wt% the fillers act as reinforced materials to the composites. Young modulus also increases with increasing filler loading, whereas elongation at break shows no significant changes. Aging test results show that the tensile strength and elongation at break decrease and Young modulus increases with aging for RHP composites. However, for silica composites, there were no significant changes in Young modulus and elongation at break except reduction of tensile strength. The water uptake in RHP composites is higher than silica composites. Scanning electron microscopy on fracture surface shows poor filler matrix adhesion with the increasing of filler loading in the composite. This explains the reduction of tensile strength before and after aging with increasing filler loading.
Analysis of Discontinuous Space Vector PWM Techniques for a Seven-Phase Voltage Source Inverter

This paper presents discontinuous space vector PWM (DPWM) techniques for a seven-phase voltage source inverter (VSI). Space vector model of a seven-phase VSI shows that there exist 128 space vectors with different lengths and maps into fourteen sided polygons. A number of possibilities could arise to implement modulation of inverter legs due to large number of available space voltage vectors. Two strategies are adopted here; one utilising large and two middle sets of space vectors to implement discontinuous space vector PWM. Clamping of legs of inverter to either positive or negative dc bus leads to discontinuity in the switching and consequently offers reduced switching loss modulation strategy. A significant reduction in switching losses can be achieved while employing DPWM in a seven-phase VSI. A generalised method is also proposed to realize the DPWM in a seven-phase VSI. Comparison of continuous and discontinuous PWM is presented in terms of switching current ripple. The experimental set-up is illustrated and the experimental results are presented. DOI: http://dx.doi. org/10.11591/ijpeds.v2i2. 244
Interlayer exciton dynamics in a dichalcogenide monolayer heterostructure

In heterostructures consisting of different transition-metal dichalcogenide monolayers, a staggered band alignment can occur, leading to rapid charge separation of optically generated electron–hole pairs into opposite monolayers. These spatially separated electron–hole pairs are Coulomb-coupled and form interlayer excitons. Here, we study these interlayer excitons in a heterostructure consisting of MoSe2 and WSe2 monolayers using photoluminescence spectroscopy. We observe a non-trivial temperature dependence of the linewidth and the peak energy of the interlayer exciton, including an unusually strong initial redshift of the transition with temperature, as well as a pronounced blueshift of the emission energy with increasing excitation power. By combining these observations with time-resolved photoluminescence measurements, we are able to explain the observed behavior as a combination of interlayer exciton diffusion and dipolar, repulsive exciton-exciton interaction.
Interferon-λ Contributes to Innate Immunity of Mice against Influenza A Virus but Not against Hepatotropic Viruses

Virus-infected cells secrete a broad range of interferon (IFN) subtypes which in turn trigger the synthesis of antiviral factors that confer host resistance. IFN-α, IFN-β and other type I IFNs signal through a common universally expressed cell surface receptor, whereas IFN-λ uses a distinct receptor complex for signaling that is not present on all cell types. Since type I IFN receptor-deficient mice (IFNAR10/0) exhibit greatly increased susceptibility to various viral diseases, it remained unclear to which degree IFN-λ might contribute to innate immunity. To address this issue we performed influenza A virus infections of mice which carry functional alleles of the influenza virus resistance gene Mx1 and which, therefore, develop a more complete innate immune response to influenza viruses than standard laboratory mice. We demonstrate that intranasal administration of IFN-λ readily induced the antiviral factor Mx1 in mouse lungs and efficiently protected IFNAR10/0 mice from lethal influenza virus infection. By contrast, intraperitoneal application of IFN-λ failed to induce Mx1 in the liver of IFNAR10/0 mice and did not protect against hepatotropic virus infections. Mice lacking functional IFN-λ receptors were only slightly more susceptible to influenza virus than wild-type mice. However, mice lacking functional receptors for both IFN-α/β and IFN-λ were hypersensitive and even failed to restrict usually non-pathogenic influenza virus mutants lacking the IFN-antagonistic factor NS1. Interestingly, the double-knockout mice were not more susceptible against hepatotropic viruses than IFNAR10/0 mice. From these results we conclude that IFN-λ contributes to inborn resistance against viral pathogens infecting the lung but not the liver.
Direct Interaction between DNA Methyltransferase DIM-2 and HP1 Is Required for DNA Methylation in Neurospora crassa

ABSTRACT DNA methylation is involved in gene silencing and genomic stability in mammals, plants, and fungi. Genetics studies of Neurospora crassa have revealed that a DNA methyltransferase (DIM-2), a histone H3K9 methyltransferase (DIM-5), and heterochromatin protein 1 (HP1) are required for DNA methylation. We explored the interrelationships of these components of the methylation machinery. A yeast two-hybrid screen revealed that HP1 interacts with DIM-2. We confirmed the interaction in vivo and demonstrated that it involves a pair of PXVXL-related motifs in the N-terminal region of DIM-2 and the chromo shadow domain of HP1. Both regions are essential for proper DNA methylation. We also determined that DIM-2 and HP1 form a stable complex independently of the trimethylation of histone H3K9, although the association of DIM-2 with its substrate sequences depends on trimethyl-H3K9. The DIM-2/HP1 complex does not include DIM-5. We conclude that DNA methylation in Neurospora is largely or exclusively the result of a unidirectional pathway in which DIM-5 methylates histone H3K9 and then the DIM-2/HP1 complex recognizes the resulting trimethyl-H3K9 mark via the chromo domain of HP1.
Improved cytoplasmic pH measurements in SNARF-1 stained plant cells by image processing

Cytoplasmic pH has long been considered to act as a secondary messenger of various cellular responses by affecting the ionization state of proteins.1 In plant biology, cytoplasmic pH has traditionally been measured, especially in guard cells and as a response to plant microorganism interactions, with pH-sensitive microelectrodes.2 More recently, the development of fluorescent pH markers, such as BCECF and SNARF-1, has allowed us to monitor cytoplasmic pH without the need for electrophysiological equipment. However, because of vacuolar structures that occupy a large volume of plant cells, simple measurements of fluorescent intensities are insufficient to provide precise cytoplasmic pH values. In this addendum, we describe our improved method to monitor cytoplasmic pH in plant cells stained by SNARF-1 by image processing using a noise-reducing filter after determination of an optimal ROI size. In addition, further developments for automated region extraction are proposed.
Automatic induction of FrameNet lexical units

Most attempts to integrate FrameNet in NLP systems have so far failed because of its limited coverage. In this paper, we investigate the applicability of distributional and WordNet-based models on the task of lexical unit induction, i.e. the expansion of FrameNet with new lexical units. Experimental results show that our distributional and WordNet-based models achieve good level of accuracy and coverage, especially when combined.
DYNAMIC CHANGES IN THE ULTRASTRUCTURE OF THE ACINAR CELL OF THE RAT PAROTID GLAND DURING THE SECRETORY CYCLE

Synchronization of the secretory cycle in vivo was obtained by injecting isoprenaline as an inducer of secretion. A quantitative correlation between enzyme release, its subsequent reaccumulation, and the sequence of ultrastructural changes was found. At the ultrastructural level secretion was paralleled by depletion of zymogen granules through fusion of the granule membrane with the lumen membrane and discharge of the content. Each zymogen granule membrane, once connected with the lumen, acted as a lumen membrane. Fusion was thus sequential and resulted in a dramatic enlargement of the lumen space. During the entire process the passage between the lumen and the intercellular space remained blocked by the tight junctions, as shown by their impenetrability to ferritin. Reduction of the lumen size following enzyme discharge seemed to be achieved by withdrawal of lumen membrane in the form of small smooth vesicles which appeared mostly in the apical part of the cell. At the same time, the cell retracted towards the lumen, the whole process being completed within 2 hr from onset of secretion. Disappearance of the smooth vesicle followed, concomitant with formation of many condensing vacuoles and appearance of mature zymogen granules. The fate of the zymogen granule membrane, including its fusion with the lumen membrane, resorption in the form of small smooth vesicles, and its eventual reutilization mediated by the Golgi system, is discussed.
Stress Hormone Is Implicated in Satellite‐Caller Associations and Sexual Selection in the Great Plains Toad

The effects of androgens on male‐typical traits suggest that variation among males in circulating levels can play a major role in sexual selection. We examined whether variation in vocal attractiveness is attributable to differences in androgen levels among Great Plains toads (Bufo cognatus). We found that noncalling “satellite” males practicing an alternative mating tactic were more likely to associate with males producing long calls. However, callers with satellites did not have higher androgen levels than callers without satellites. Rather, callers with satellites had significantly lower corticosterone (CORT) levels than callers without satellites. A CORT manipulation experiment suggested that differences in calls for males with and without satellites were related to differences in CORT levels. Furthermore, there was a negative correlation between CORT level and call duration within most nights of chorus activity. However, the correlation was weak for the pooled data (across all nights), suggesting that local environmental and/or social factors also affect call duration. Last, we show that females preferred broadcast calls of longer duration, characteristic of males with satellites and low CORT. These results imply that satellites optimize their reproductive success by associating with males producing long calls. However, this association should negatively affect the fitness of attractive callers.
Diethyldithiocarbamate Potentiates the Neurotoxicity of In Vivo l‐Methyl‐4‐Phenyl‐1, 2, 3, 6‐Tetrahydropyridine and of In Vitro 1‐Methyl‐4‐Phenylpyridinium

Diethyldithiocarbamic acid (DDC) potentiates in vivo neurotoxicity of 1‐methyl‐4‐phenyl‐1, 2, 3, 6‐tetrahydropyridine (MPTP) and in vitro neurotoxicity of 1‐methyl‐4‐phenylpyridinium (MPP+). Male C57B1/6 mice were given two or five injections of MPTP (30 rag/kg i.p.) preceded 0.5 h by DDC (400 mg/kg i.p.). The mice were tested for catalepsy, akinesia, or motor activity during and after the period of dosing. Striatal and hippocampal tissues were obtained at 2 and 7 days following the last injection and evaluated for dopamine and norepinephrine levels, respectively. These same tissues were also analyzed for the levels of glial fibrillary acidic protein (GFAP), an astrocyte‐localized protein known to increase in response to neural injury. Pretreatment with DDC potentiated the effect of MPTP in striatum and resulted in substantially greater dopamine depletion, as well as a more pronounced elevation in GFAP. In hippocampus, the levels of norepinephrine and GFAP were not different from controls in mice receiving only MPTP, but pretreatment with DDC resulted in a sustained depletion of norepinephrine and an elevation of GFAP, suggesting that damage was extended to this brain area by the combined treatment. Mice receiving MPTP preceded by DDC also demonstrated a more profound, but reversible, catalepsy and akinesia compared to those receiving MPTP alone. Systemically administered MPP+ decreased heart norepinephrine, but did not alter the striatal levels of dopamine or GFAP, and pretreatment with DDC did not alter these effects, but did increase lethality. DDC is known to increase brain levels of MPP+ after MPTP, but our data indicate that this is not due to a movement of peripherally generated MPP+ into CNS. In cultured bovine adrenal medullary cells, MPP+ (300 μM) slightly decreased catecholamine levels, but had no effect on tyrosine hydroxylase activity or cellular protein. However, the incubation of these cells with both MPP+ and DDC (1.5 or 3.0 mM) caused large decreases in all indicators of cell viability. The enhancement of MPP+ neurotoxicity by DDC in an in vitro system, where distributional factors are limited, raises die possibility that mechanisms in addition to altered kinetics may account for DDC‐induced potentiation of MPTP neurotoxicity in vivo.
Pseudohallucinations: a pseudoconcept? A review of the validity of the concept, related to associate symptomatology.

"Pseudohallucination" is a concept used in the classification of nonpsychotic perceptual disorders. This report describes the history of the concept and investigates whether pseudohallucinations can be differentiated from related psychopathological symptoms, such as hallucinations, re-experiencing, and dissociative phenomena. We performed a literature review, which shows that pseudohallucinations and related symptoms have low construct validity and are, accordingly, clinically ambiguous. Most likely, pseudohallucinations are placed on an overlapping continuum of symptomatology that includes perceptual disorders, re-experiencing, (dissociative) imagery, and normal thought and memory processes. Recommendations are made regarding the specification of dimensions of this continuum. The term "nonpsychotic hallucinations" is preferred over "pseudohallucination. "