Miracle-dz/UniFAR-FTUs huggingface dataset:
Barriers to Treatment and Control of Hypertension among Hypertensive Participants: A Community-Based Cross-sectional Mixed Method Study in Municipalities of Kathmandu, Nepal

Introduction Despite the established evidence on benefits of controlling raised blood pressure and development of several guidelines on detection and management of hypertension, people often have untreated or uncontrolled hypertension. In this context, we undertook this study to identify the barriers existing in hypertension treatment and control in the municipalities of Kathmandu district in Nepal. Methods This was a community based, cross-sectional mixed method study conducted in the municipalities of Kathmandu district in Nepal between January and July 2015. Among 587 randomly selected participants, the aware hypertensive participants were further assessed for the treatment and control of hypertension. For qualitative component, 20 participants having uncontrolled hypertension took part in two focused group discussions and two cardiac physicians participated in in-depth interviews. Results Out of 587 participants screened, 191 (32.5%) were identified as hypertensive. Among 191 hypertensive participants, 118 (61.8%) were aware of their problem. Of the 118 aware hypertensive participants, 93 (78.8%) were taking medicines, and among those treated, 46 (49.6%) had controlled hypertension. Proportions of participants taking anti-hypertensive medications varied significantly with age groups, ethnicity, occupation and income. Hypertension control was significantly associated with use of combination therapy, adherence to medication, follow-up care, counseling by health-care providers, and waiting time in hospital. Being worried that the medicine needs to be taken lifelong, perceived side effects of drugs, non-adherence to medication, lost to follow-up, inadequate counseling from physician, and lack of national guidelines for hypertension treatment were the most commonly cited barriers for treatment and control of hypertension in qualitative component of the research. Conclusion Large proportion of the hypertensive population has the untreated and the uncontrolled hypertension. Efforts to dispel and dismantle the myths and barriers related to hypertension treatment and control are warranted to reduce the consequences of uncontrolled hypertension.
Theorizing Subjectivity in Organizations: The Failure of Foucauldian Studies?

This paper examines the promise of Foucault as a vehicle for addressing subjectivity and organizations. It questions the supposed non-essentialism and nondualism of Foucauldian work, and argues that such work has difficulties in theorizing agency, and the relation between self and discourse. Though the paper is critical of previous attacks on the anti-materialistic stance of Foucauldian work, it nevertheless suggests that Foucauldian studies have been unable to adequately theorize 'material' relations, and that they have so far provided an inadequate basis by which to develop an ethics of either individual or collective change. In developing this critique, the paper largely focuses on Foucauldian work rather than the text of Foucault himself, though some attention is paid to Volumes 1 to 3 of The History of Sexuality. Feminist work is also employed in order to illustrate the limitations of Foucault in theorizing the self and subjectivity.
Type-2 fuzzy multiagent traffic signal control

This paper proposes a controller design for urban traffic networks. The growing demand for faster transportation has led to heavy congestion in road traffic networks, necessitating the need for traffic-responsive intelligent signal control systems. The developed signal control system based on uncertain information of the environment must be capable of determining the green time that minimizes the overall delay. The proposed traffic controller is based on distributed multi-agent approach which is very efficient considering the uncertainties and parameter variations. The effectiveness of the proposed control method is verified by comparing the obtained result with that of a fixed time controller.
MINDFULNESS, ATTACHMENT STYLE AND CONFLICT RESOLUTION BEHAVIORS IN ROMANTIC RELATIONSHIPS

ii ACKNOWLEDGEMENTS iii TABLE OF CONTENTS iv LIST OF FIGURES vii LIST OF TABLES viii LIST OF APPENDICES ix INTRODUCTION 1 REVIEW OF LITERATURE 3 Relationships 3 Attachment style 3 Communication 9 Mindfulness 13 Conceptualization 13 Practicing Mindfulness 14 Clinical Research 18 STATEMENT OF THE PROBLEM 29 Attachment Style 29 Conflict Resolution Behaviors 31 Mindfulness 32 Hypotheses 36 vi METHOD 39 Participants and Procedures 49 Measures 44 Data Analysis 48 Risks and Benefits 49 RESULTS 50 Primary Analyses 50 Inferential Analyses 53 DISCUSSION 64 Discussion of Results 64 Discussion of Limitations 69 Suggestions for Future Research 71 REFERENCES 73 APPENDIX A 79 APPENDIX B 82 APPENDIX C 86 APPENDIX D 88 APPENDIX E 90 APPENDIX F 93
Regulation of the innate immune responses in the silkworm, Bombyx mori

Insects possess an effective innate immune system against foreign microorganisms. Innate immunity of insects is divided into two major reaction types: humoral and cellular reactions. Humoral reactions involve soluble proteins in the hemolymph such as phenoloxidase, antimicrobial proteins (AMPs), lysozymes, and lectins, whereas hemocytes mediate cellular reactions such as phagocytosis, encapsulation and nodule formation. In Bombyx mori, six different families of AMPs have been identified: Cecropin, Attacin, Lebocin, Moricin, Gloverin, and Defensin. One lysozyme and three lysozyme-like proteins, one of which is involved in elimination of invading pathogens, are also found in the silkworm. Both lysine-containing peptidoglycan (Lys-PGN) and meso-diaminopimelic acid containing peptidoglycan (DAP-PGN) trigger expression of AMP genes, probably through the Toll and IMD pathways, respectively. DAP-PGN has stronger elicitor activity than Lys-PGN in B. mori because of the difference in transcriptional activity between BmRelishes and BmRels, which are effectors of the IMD and Toll pathways, respectively. Furthermore, two recognition proteins and a serine protease are involved in activation of prophenoloxidase for melanization, and several C-type lectins, which participated in cellular reactions, were identified in B. mori. Moreover, a paralytic peptide was reported to play important roles in silkworm immunity. Recent development of transgenic technologies and silkworm genome information are expected to accelerate silkworm immunity studies.
Factors Influencing [F‐18] 2‐Fluoro‐2‐Deoxy‐d‐Glucose (F‐18 FDG) Uptake in Melanoma Cells: The Role of Proliferation Rate, Viability, Glucose Transporter Expression and Hexokinase Activity

Using human (SK‐MEL 23, SK‐MEL 24 and G361) and murine (B16) melanoma cell lines, the coregulatory potential of the uptake of the positron emission tomography (PET) tracer, [Fluorine‐18] 2‐fluoro‐2‐deoxy‐d‐glucose (F‐18 FDG) has been investigated in relationship to tumor characteristics. Comparative studies among the four melanoma cell lines demonstrated that the lowest FDG uptake in SK‐MEL 24 corresponded strongly to the data for DT (population doubling time) and MTT (tetrazolium salt) cell viability as well as hexokinase (HK) activity, but was not related to the glucose transporter 1 (GLUT 1) expression level. Furthermore, the FDG uptake in each melanoma cell line measured by cell cycle kinetics was significantly positively correlated to both the proliferation index (PI=S/G2M phase fractions) and the cell viability, though with one exception relating to the PI of the lowest FDG uptake cell line, SK‐MEL 24. No positive correlation was found between the expression of GLUT 1 and FDG uptake in any individual cell line. However, the HK activities in SK‐MEL 23 and 24 showed considerable positive relationships with FDG uptake. Our present study suggests that both the proliferation rate and the cell viability of melanoma cells may be key factors for FDG uptake and that HK activity, rather than GLUT 1 expression, seems to be a major factor.
A study on adaptive stimulation of the basal ganglia as a treatment for Parkinsonism

The purpose of this dissertation is to design an automated system for the modification of Deep Brain Stimulation (DBS) parameters based on specific identifiers in the neuronal response of Parkinsonian patients undergoing DBS treatment. The neural response patterns are obtained from an artificial neural network consisting of dynamic neuron and synapse components and programmed to exhibit a response to pulse stimuli that resembles the activity in the subthalamic nucleus of Parkinsonian patients undergoing DBS treatment. Moreover, using pulse stimuli of varying specification, a band-pass filtered response of the network is subjected to a set of signal processing techniques including Linear Predictive Coding (LPC), Autoregressive Moving Average (ARMA) modeling, Discrete Fourier Transform (DFT), moments and higher order statistics, producing a set of results or features. Then, each feature is evaluated to determine the effectiveness, in terms of error probability, of discerning between different neuronal responses to pulse stimuli. Furthermore, a digital circuit is designed at the transistor level for computing the 1st LPC coefficient of recorded neural data and also autonomously regulating the specifications of the stimulus waveform based on the value of the computed coefficient. Also, the circuit design is optimized using a pipeline to reduce dynamic power dissipation. Moreover, it is suggested that a similar design may be useful in automating the administration of DBS as a treatment for Parkinsonism with only a minimal additional power demand. %%%%
Epidemiology of Melioidosis

Melioidosis is one of the few genuinely tropical diseases well established in Southeast Asia and northern Australia. Though highly fatal consequence of septicemic melioidosis reported from tropical and developed countries is appalling, the disease has not attracted the attention that some recently recognized exotic diseases have received. In addition, melioido­ sis poses no threat to developed countries since there is no convincing data with regards to establishment and spread of the disease after importation. Discovery of Pseudomonas pseudomallei ori­ ginated in April 1911 at Pathological Laboratory, Rangoon, by Whitmore and Krishnaswami1 when a Burmese "morphia" addict aged 10 years succumbed from pneumonitis. Postmortem findings of the fIrst reported case revealed peculiar cheesy consolidation of the lung and several subcutaneous abscesses on his thighs. Specimen culture of the former grew out only B. mallei. Subsequent reports described Pseudomonas pseudomallei under variety of names including B. Whitmori, Pfeifferella whitmori, Pfeifferella pseudo­ mallei, Actinobacillus pseudomalle~ Loefferella whit mori and Malleomyces pseudomallei. 2 5 Until clini­ cians have been familiar with various clinical features of melioidosis and laboratory personnels are aware of this organism, the disease is yet to be discovered more frequently in endemic tropical countries as happened to Hong Kong6 and Thailand7 ,8 and, due to increasing mobility of people, in other parts of the world.
A Plan for Sustainable MIR Evaluation

The Music Information Retrieval Evaluation eXchange (MIREX) is a valuable community service, having established standard datasets, metrics, baselines, methodologies, and infrastructure for comparing MIR methods. While MIREX has managed to successfully maintain operations for over a decade, its long-term sustainability is at risk. The imposed constraint that input data cannot be made freely available to participants necessitates that all algorithms run on centralized computational resources, which are administered by a limited number of people. This incurs an approximately linear cost with the number of submissions, exacting significant tolls on both human and financial resources, such that the current paradigm becomes less tenable as participation increases. To alleviate the recurring costs of future evaluation campaigns, we propose a distributed, community-centric paradigm for system evaluation, built upon the principles of openness, transparency, reproducibility, and incremental evaluation. We argue that this proposal has the potential to reduce operating costs to sustainable levels. Moreover, the proposed paradigm would improve scalability, and eventually result in the release of large, open datasets for improving both MIR techniques and evaluation methods.
VHF-LB VEST ANTENNA A. Jafargholi and A. Hosseinbeig Department of Electrical Engineering

In this paper, a new simple VHF-LB vest antenna is proposed, simulated, fabricated and tested. The simulation results for various user’s positions such as standing, kneeling and prone on the ground are obtained and compared with conventional whip antenna mounted on mobile unit. It is shown that the proposed antenna outperforms the whip antenna in terms of gain and body energy absorption. The measurements results of proposed vest antenna confirm the simulation results.
Towards Alternative Ways to Measure Attitudes Related to Consumption: Introducing Startle Reflex Modulation

Evolution provided us with the important feature of affective information processing, which is designed to detect potentially harmful and appetitive sources in a dynamic environment. Transferred into the modern world of consumption research, we are interested in studying this particular approach versus avoidance behavior. We call it affective information processing which is the underlying basis of all emotions and a significant part of attitudes relevant to consumption. This paper provides conceptual and measurement-related reflections on our understanding of attitudes and emotions relevant to consumption.
Meditation - A Powerful Stress Buster in Dental Care Professionals

Meditation is an umbrella term that encompasses a family of practices. In state of meditation there is total relaxation of body & mind. Control of breathing & doing nothing are the basic steps. The practice of meditation creates a balanced, rhythmic & naturally flowing pulsation of life through every part of the body. It transfers the struggling- stressful & exhausted life into a peaceful one. That life is full of health, creativity, love & compassion. Such type of greatest adventure only 'human mind' can undertake. For meditation, there is no need to escape from the life. It is a simple technique that does not require sophisticated or complicated amenities.
3-Hydroxyterphenyllin, a natural fungal metabolite, induces apoptosis and S phase arrest in human ovarian carcinoma cells

In the present study, we evaluated 3-Hydroxyter-phenyllin (3-HT) as a potential anticancer agent using the human ovarian cancer cells A2780/CP70 and OVCAR-3, and normal human epithelial ovarian cells IOSE-364 as an in vitro model. 3-HT suppressed proliferation and caused cytotoxicity against A2780/CP70 and OVCAR-3 cells, while it exhibited lower cytotoxicity in IOSE-364 cells. Subsequently, we found that 3-HT induced S phase arrest and apoptosis in a dose-independent manner. Further investigation revealed that S phase arrest was related with DNA damage which mediated the ATM/p53/Chk2 pathway. Downregulation of cyclin D1, cyclin A2, cyclin E1, CDK2, CDK4 and Cdc25C, and the upregulation of Cdc25A and cyclin B1 led to the accumulation of cells in S phase. The apoptotic effect was confirmed by Hoechst 33342 staining, depolarization of mitochondrial membrane potential and activation of cleaved caspase-3 and PARP1. Additional results revealed both intrinsic and extrinsic apoptotic pathways were involved. The intrinsic apoptotic pathway was activated through decreasing the protein levels of Bcl2, Bcl-xL and procaspase-9 and increasing the protein level of Puma. The induction of DR5 and DR4 indicated that the extrinsic apoptotic pathway was also activated. Induction of ROS and activation of ERK were observed in ovarian cancer cells. We therefore concluded that 3-HT possessed anti-proliferative effect on A2780/CP70 and OVCAR-3 cells, induced S phase arrest and caused apoptosis. Taken together, we propose that 3-HT shows promise as a therapeutic candidate for treating ovarian cancer.
Effect of smoking on MAP kinase-induced modulation of IL‐8 in human alveolar macrophages

Inflammatory cytokine production by alveolar macrophages (AMs) is regulated by transcriptional activation and may be increased by cigarette smoking. The smoking-induced regulation of interleukin (IL)‐8 by extracellular signal-regulated kinase (ERK)‐1 and ‐2, p38 mitogen-activated protein kinase (MAPK) and the transcription factor nuclear factor‐κB (NF‐κB) in lipopolysaccharide-stimulated AMs was assessed in nine smokers compared with nine healthy nonsmokers. IL‐8 production was dependent on phosphorylation of ERK‐1 and ‐2 and p38 MAPK, as examined by PD 098059 (10 µM), an inhibitor of the upstream activator of MAPK kinase (MKK)‐1, and SB 203580 (10 µM), an inhibitor of p38 MAPK. IL‐8 release and the inhibitory effect of PD 098059 were increased in AMs from smokers. Moreover, ERK‐2 messenger ribonucleic acid expression, as examined by reverse transcriptase polymerase chain reaction and phosphorylation of ERK‐2 using Western blots, were increased in AMs from smokers, indicating a smoking-induced modulatory role of ERK‐1 and ‐2. Lipopolysaccharide-induced IL‐8 production was dependent on activation of NF‐κB, as examined by SN 50 (100 µM), an inhibitor of NF‐κB translocation, and the specific NF‐κB inhibitor kinase‐2 inhibitor, AS 602868 (10 µM), with no differences in AMs from smokers and nonsmokers. SN 50 but not PD 098059 and SB 203580 blocked NF‐κB deoxyribonucleic acid-binding, and this occurred to the same extent in AMs from smokers and nonsmokers, as examined by electromobility shift assay. It is concluded that cigarette smoking enhances mitogen-activated protein kinase activation more than nuclear factor‐κB activation to increase lipopolysaccharide-induced interleukin‐8 production in alveolar macrophages.
Assessing Academic Performance between Traditional and Distance Education Course Formats

The goal of this study was to explore whether differences in student academic indicators exist between taking a course face-to-face (F2F) and taking a course via distance education (DE). Three hundred and eighty five students were enrolled in a course offered, both, as F2F (n = 116) and as DE (n = 269). Course content, instructor, textbook adopted, and assessment methods were consistent between the two course delivery formats. Final grades, DFW rates, and end of term course and instructor evaluations were used as the outcome indicators. In addition, student demographic information was factored into data analyses. Results indicated that there was a statistically significant difference in final grade, DFW rates, and end of term course evaluation response rates between the course offerings. Further analysis suggested that freshman grade performance was significantly different between course offerings. Implications and policy suggestions regarding distance education will be discussed.
DOMAIN BUILDING OR RISK TAKING? (In-)equality in Danish School Management

The Nordic Countries are usually seen as the worlds must successful nations when it comes to gender equality, and the Scandinavian population in general appreciates values traditionally labeled feminine as caretaking and the quality of everyday life. However, the inequalities become obvious in school management. Among headmasters in High school in Denmark only 18 % are women despite of the fact that 52 % of the teachers are female. How can we explain that? This article is based on a survey answered by top- and middle level management staff. It rejects all traditional explanations of the relations between gender, values and family obligation but reveals an interesting difference between two strategies for career development: Domain Building and Risk Taking . Both strategies are applied by both men and women. However, one of them seems to be the most effective with regard to achieve a position as a top manager – and one of them is more often preferred by men than by women.
Stabilization of Markov jump linear systems over Gaussian relay channel

This paper deals with the problem of mean square (MS) stabilization for a Markov jump linear system (MJLS) over Gaussian relay channel subject to average power constraint. Based on the theory of entropy, a necessary condition of channel capacity for MS stabilization is proposed. Then by using the Schalkwijk-Kailath encoding scheme, a sufficient condition of MS stabilization is derived for a scalar MJLS. Finally, a numerical example is given to show the show the effectiveness and correctness of the theoretical work.
The ability of general practitioners to detect mental disorders in primary health care

The ability to detect mental disorders varies greatly among general practitioners in primary health care. The aim of this study was to determine the factors underlying the differences between general practitioners in the ability to recognize mental disorders in Finnish patient populations. The group studied consisted of 1000 randomly selected adult patients of primary care facilities in the city of Turku. The Symptom Checklist (SCL‐25) was used as the reference method in the identification of psychiatric cases. According to the SCL‐25, one fourth of the sample had mental disorders. A good recognition ability was associated with postgraduate psychiatric training and qualification as a specialist in general practice. Surprisingly, Balint group training, which is a method intended to improve the ability of general practitioners to manage their patients' mental health problems, was associated rather with poor than good detection ability.
Research report. Interacting with huge hierarchies: beyond cone trees

The paper describes an implementation of a tool for visualizing and interacting with huge information hierarchies, and some preliminary empirical evaluation of the tool's efficacy. Existing systems for visualizing huge hierarchies using cone trees "break down" once the hierarchy to be displayed exceeds roughly 1000 nodes, due to increasing visual clutter. The paper describes a system called fsviz which visualizes arbitrarily large hierarchies while retaining user control. This is accomplished by augmenting cone trees with several graphical and interaction techniques: usage-based filtering, animated zooming, hand-coupled rotation, fish-eye zooming, coalescing of distant nodes, texturing, effective use of colour for depth cueing, and the applications of dynamic queries. The fsviz system also improves upon earlier cone tree visualization systems through a more elaborate node layout algorithm. This algorithm enhances the usefulness of cone tree visualization for large hierarchies by all but eliminating clutter.