Miracle-dz/UniFAR-FTUs huggingface dataset:
High-frequency neural oscillations and visual processing deficits in schizophrenia

Visual information is fundamental to how we understand our environment, make predictions, and interact with others. Recent research has underscored the importance of visuo-perceptual dysfunctions for cognitive deficits and pathophysiological processes in schizophrenia. In the current paper, we review evidence for the relevance of high frequency (beta/gamma) oscillations towards visuo-perceptual dysfunctions in schizophrenia. In the first part of the paper, we examine the relationship between beta/gamma band oscillations and visual processing during normal brain functioning. We then summarize EEG/MEG-studies which demonstrate reduced amplitude and synchrony of high-frequency activity during visual stimulation in schizophrenia. In the final part of the paper, we identify neurobiological correlates as well as offer perspectives for future research to stimulate further inquiry into the role of high-frequency oscillations in visual processing impairments in the disorder.
Global versus cultural approaches in public relationship management: The case of the European Union

Purpose – The aim of this paper is to present and compare two approaches (the global and the cultural) to public relationship management and to argue by reference to different cases, why the cultural approach can be considered more effective in establishing good relationships in different national cultural contexts.Design/methodology/approach – The discussion identifies some of the limitations of recent thinking regarding the nature of a global public and the possibility to define and treat international publics as a global public in public relationship management. As validation of this claim, cases in the European context are presented to show that a cultural approach provides better interpretations of human behaviour in different national contexts and thus better understanding of organisations' publics.Findings – It is argued, that the idea of a global public in public relationship management does not work in different national cultural contexts, while the traditional cultural approach can work in situa.
Active calibration and its applications on micro-operating platform with multiple manipulators

The microscope has characteristics of a planar vision with small view field and small view depth. For micro operation systems with multiple manipulators, the handling of irregular objects may lead to a nonorthogonal microscopic system, which needs to focus on clear viewing interested features, and it may also hardly locate the exact position and posture of the robot arms. In view of these, this paper proposes an active calibration method to compute image Jacobian matrix, which maps from the relative motion of the manipulators to the image coordination changes in the microscopes. We also investigate the applications in micro operator positioning, tracking for distributed systems, and movement optimization in micro-assembly. Experiments are carried out on a micro-assembly platform equipped with three microscopes and six robot arms, and the results validate the effectiveness of the proposed method.
"Bringing women up to equality with men" : paradoxically redressing and reifying gendered recruitment and selection practices in Australian sport workplaces?

In Australia, as in other developed countries, legislative and policy enactment has, in part, enabled the more equitable involvement of women and minorities, especially in workplace contexts where men and normative masculinities dominate. Despite some meaningful change, many Australian sport workplaces continue to be contexts in which femininities and non-normative masculinities are marginalised and devalued. Using Australian sport organisation recruitment and selection policies and official organisation practices as a research domain this paper interrogates how in subtle and paradoxical ways equal employment opportunity legislation can simultaneously redress and reify gendered recruitment and selection inequities.
Purification and characterization of human RNPS1: a general activator of pre‐mRNA splicing

Biochemical purification of a pre‐mRNA splicing activity from HeLa cells that stimulates distal alternative 3′ splice sites in a concentration‐dependent manner resulted in the identification of RNPS1, a novel general activator of pre‐mRNA splicing. RNPS1 cDNAs, encoding a putative nucleic‐acid‐binding protein of unknown function, were previously identified in mouse and human. RNPS1 is conserved in metazoans and has an RNA‐recognition motif preceded by an extensive serine‐rich domain. Recombinant human RNPS1 expressed in baculovirus functionally synergizes with SR proteins and strongly activates splicing of both constitutively and alternatively spliced pre‐mRNAs. We conclude that RNPS1 is not only a potential regulator of alternative splicing but may also play a more fundamental role as a general activator of pre‐mRNA splicing.
Photoprotection in Cyanobacteria: Regulation of Light Harvesting †

To cope with a rapidly fluctuating light environment, vascular plants and algae have evolved a photoprotective mechanism that serves to downregulate the transfer of excitation energy in the light‐harvesting complexes to the photosynthetic reaction centers. This process dissipates excess excitation energy in the chlorophyll pigment bed by a nonradiative pathway. Since this pathway competes with and therefore quenches chlorophyll fluoresence in a nonphotochemical manner, it has been termed Non‐photochemical Quenching (NPQ). For many years, cyanobacteria were not considered capable of performing NPQ as a photoprotective mechanism. Instead, the redistribution of the phycobilisome (PBS) light‐harvesting antenna between reaction centers by a process called state transitions was considered the major means of regulating the utilization of harvested light energy. Recently, it was demonstrated that cyanobacteria are able to use NPQ as one component of their photoprotective strategies. Cyanobacteria exhibit significant NPQ during nutrient‐replete growth, but it becomes a more prominent means of managing absorbed excitation energy when the cells experience iron starvation. Rapid progress in understanding the molecular mechanism of cyanobacterial NPQ has revealed a process that is very distinct from the functionally analogous process in plants and algae. Cyanobacterial NPQ involves the absorption of blue light by a carotenoid binding protein, termed the Orange Carotenoid Protein, and most likely involves quenching in the PBS core. In this study, we summarize work leading to the discovery of NPQ in cyanobacteria and the elucidation of molecular mechanisms associated with this important photoprotective process.
Clinical management of binocular vision : heterophoric, accommodative, and eye movement disorders

Part I: DIAGNOSIS AND GENERAL TREATMENT APPROACH Ch. 1: Diagnostic Testing Ch. 2: Case Analysis and Classification Ch. 3: General Treatment Modalities, Guidelines, and Prognosis Ch. 4: Primary Care of Binocular Vision, Accommodative and Eye Movement Disorders Part II: VISION THERAPY PROCEDURES AND INSTRUMENTATION Ch. 5: Introduction and General Concepts Ch. 6: Fusional Vergence, Voluntary Convergence, and Antisuppression Procedures Ch. 7: Accommodative Techniques Ch. 8: Ocular Motility Procedures Part III: MANAGEMENT Ch. 9: Low AC/A Conditions: Convergence Insufficiency and Divergence Insufficiency Ch. 10: High AC/A Conditions: Convergence Excess and Divergence Excess Ch. 11: Normal AC/A Conditions: Fusional Vergence Dysfunction, Basic Esophoria, and Basic Exophoria Ch. 12: Accommodative Dysfunction Ch. 13: Eye Movement Disorders Ch. 14: Cyclovertical Heterophoria Ch. 15: Fixation Disparity Part IV: ADVANCED DIAGNOSTIC AND MANAGEMENT ISSUES Ch. 16: Interactions Between Accommodation and Vergence Ch. 17: Refractive Amblyopia Ch. 18: Nystagmus Ch. 19: Aniseikonia Ch. 20: Binocular and Accommodative Problems Associated with Computer Use Ch. 21: Binocular and Accommodative Problems Associated with Acquired Brain Injury Ch. 22: Binocular and Accommodative Problems Associated with Learning Problems Ch. 23: Development and Management of Refractive Error: A Binocular Vision-Based Model Ch. 24: Binocular Vision Problems Associated with Refractive Surgery Part V: VISION THERAPY AND OPTOMETRIC PRACTICE Ch. 25: Patient and Practice Management Issues in Vision Therapy APPENDICES Index
Changes in Left Ventricular Ejection Fraction Predict Survival and Hospitalization in Heart Failure With Reduced Ejection Fraction

Background—Left ventricular remodeling, as commonly measured by left ventricular ejection fraction (LVEF), is associated with clinical outcomes. Although change in LVEF over time should reflect response to therapy and clinical course, serial measurement of LVEF is inconsistently performed in observational settings, and the incremental prognostic value of change in LVEF has not been well characterized. Methods and Results—The &bgr;-Blocker Evaluation of Survival Trial measured LVEF by radionuclide ventriculography at baseline and at 3 and 12 months after randomization. We built a series of multivariable models with 16 clinical parameters plus change in LVEF for predicting 4 major clinical end points, including the trial’s primary end point of all-cause mortality. Among 2484 patients with at least 1 follow-up LVEF, change in LVEF was the second most significant predictor (behind baseline creatinine) of all-cause mortality (adjusted hazard ratio for improvement in LVEF by ≥5 U responder versus nonresponder [95% confidence intervals] for all-cause mortality=0.62 [0.52–0.73]). Other end points, including heart failure hospitalization or the composite of all-cause mortality and heart failure hospitalization, yielded similar results. LVEF change ≥5 U was associated with a modest increase in discrimination when added to traditional predictors and was predictive of outcomes in both the bucindolol and placebo treatment groups. LVEF change as a predictor of outcomes was affected by sex and race, with evidence that LVEF improvement is associated with less survival benefit in African Americans and women. Conclusions—Serial evaluation for LVEF change predicts both survival and heart failure hospitalization and provides a dynamic/real-time measure of prognosis in heart failure with reduced LVEF. Clinical Trial Registration—URL: http://www.clinicaltrials. gov. Unique identifier: NCT00000560.
Why They Enjoy Teaching: The Motivation of Outstanding Technology Teachers.

Technology education has undergone radical changes over the past decade. The content, instructional methodologies, and facilities are among the key indicators of change as is the background and motivation of people who choose to become technology teachers. Individuals interested in computers and electronic communication are seeking technology teaching positions, as contrasted with interests in woodworking and metalworking that typified the past. The profession could benefit from information about how these changes have affected teachers’ enjoyment of teaching. This information could inform the process of recruiting new teachers by better understanding the rewards and stresses associated with major programmatic change. What is it about the current teaching climate in technology education that outstanding teachers find most rewarding? Technology education is having difficulty recruiting talented teachers. Current estimates place the number of job openings at six or more for each technology education baccalaureate graduate. Attractive salary and benefit packages accompany many of these openings. Why is it so difficult to attract and retain talented technology teachers? What is it about teaching technology education that makes outstanding teachers love their jobs? In conjunction with an ITEA task force, a study was conducted to determine the factors associated with college students’ decision to select technology teaching as a career. This research was designed to provide an information base for subsequent recruitment efforts (Wright & Custer, 1998). Another responsibility of the Task Force was to identify the specific aspects of teaching that outstanding, nationally-recognized technology education teachers find to be particularly rewarding and most distressing. Another goal was to obtain suggestions about changes necessary to make their jobs more enjoyable. The focus of this study is on the perceptions of outstanding technology education teachers regarding the most rewarding aspects of teaching. This information could be useful in attracting others into technology teaching. _____________________________
Dengue/dengue hemorrhagic fever: the emergence of a global health problem.

Dengue and dengue hemorrhagic fever (DHF) are caused by one of four closely related but antigenically distinct virus serotypes (DEN-1 DEN-2 DEN- 3 and DEN-4) of the genus Flavivirus. Infection with one of these serotypes does not provide cross-protective immunity so persons living in a dengueendemic area can have four dengue infections during their lifetimes. Dengue is primarily an urban disease of the tropics and the viruses that cause it are maintained in a cycle that involves humans and Aedes aegypti a domestic day-biting mosquito that prefers to feed on humans. Infection with a dengue virus serotype can produce a spectrum of clinical illness ranging from a nonspecific viral syndrome to severe and fatal hemorrhagic disease. Important risk factors for DHF include the strain and serotype of the virus involved as well as the age immune status and genetic predisposition of the patient. The first reported epidemics of dengue fever occurred in 1779-1780 in Asia Africa and North America; the near simultaneous occurrence of outbreaks on three continents indicates that these viruses and their mosquito vector have had a worldwide distribution in the tropics for more than 200 years. During most of this time dengue fever was considered a benign nonfatal disease of visitors to the tropics. Generally there were long intervals (10-40 years) between major epidemics mainly because the viruses and their mosquito vector could only be transported between population centers by sailing vessels. (excerpt)
Shift work: health, performance and safety problems, traditional countermeasures, and innovative management strategies to reduce circadian misalignment

There are three mechanisms that may contribute to the health, performance, and safety problems associated with night-shift work: (1) circadian misalignment between the internal circadian clock and activities such as work, sleep, and eating, (2) chronic, partial sleep deprivation, and (3) melatonin suppression by light at night. The typical countermeasures, such as caffeine, naps, and melatonin (for its sleep-promoting effect), along with education about sleep and circadian rhythms, are the components of most fatigue risk-management plans. We contend that these, while better than nothing, are not enough because they do not address the underlying cause of the problems, which is circadian misalignment. We explain how to reset (phase-shift) the circadian clock to partially align with the night-work, day-sleep schedule, and thus reduce circadian misalignment while preserving sleep and functioning on days off. This involves controlling light and dark using outdoor light exposure, sunglasses, sleep in the dark, and a little bright light during night work. We present a diagram of a sleep-and-light schedule to reduce circadian misalignment in permanent night work, or a rotation between evenings and nights, and give practical advice on how to implement this type of plan.
Myoclonic, atonic, and absence seizures following institution of carbamazepine therapy in children

Five children, aged 3 to 11 years, treated with carbamazepine for epilepsy, had an acute aberrant reaction characterized by the onset of myoclonic, atypical absence and/or atonic (minor motor) seizures within a few days. When the carbamazepine was discontinued, two of the children returned to their former state very quickly, two had the minor motor seizures resolve in 3 and 6 months, and one had the seizures persist. The child in whom the seizures persisted was later found to have ceroid lipofuscinosis. The other children are doing well on other anticonvulsants.
Atopic Dermatitis-Like Symptoms in HR-1 Hairless Mice Fed a Diet Low in Magnesium and Zinc

We aimed to develop an animal model for atopic dermatitis. HR-1 hairless mice fed a diet with reduced magnesium and zinc levels were compared with mice fed a standard diet. Skin dryness and wrinklelike changes, scratching behaviour, decreased skin water content, increased transepidermal water loss and raised blood immunoglobulin E levels were seen in the group receiving the reduced magnesium and zinc diet compared with control mice. There were no significant differences in body weight or the weight of the major organs between the two groups. Haematological examination in both groups was normal apart from increased immunoglobulin E levels in mice fed a reduced magnesium and zinc diet. These mice may be useful models of atopic dermatitis; preparation of the animals is not particularly time consuming, the reproducibility is 100%, and atopic dermatitis symptoms occur even in a specific pathogen-free environment.
Invasion and survival strategies of Anaplasma phagocytophilum

Anaplasma phagocytophilum is an aetiological agent of human granulocytic ehrlichiosis, an emerging tick‐borne zoonosis in the United States and Europe. This obligate intracellular bacterium is unique in that it colonizes polymorphonuclear leucocytes (neutrophils). Neutrophils are key players in innate immunity. These short‐lived phagocytes ingest invading microorganisms and destroy them by various means, which include fusing the bacteria‐containing phagosome with acidic lysosomes as well as directing toxic oxidative and proteolytic compounds into the phagosomal lumen. Its tropism for neutrophils indicates that A. phagocytophilum uses strategies for evading and/or neutralizing these microbicidal activities. This review focuses on some of the mechanisms that A. phagocytophilum uses for neutrophil adhesion, surviving within the hostile intracellular environment of its host neutrophil and for effectively disseminating to naïve host cells.
34. Community-Based Learning: Practices, Challenges, and Reflections

This paper will highlight an innovate practice in teaching and learning by reflecting on two fourth-year sociology seminar classes that participated in a community-based learning project at York University. Fifty students collaborated in three to six person teams to work on a problem/issue identified by one of five not-for-profit organizations who work with and/or for women as victims, offenders, and/or professionals in the Canadian criminal justice system. Reflections on the process and outcome of the experience offer insights into organizing and engaging in a community-based learning experience as well as point to some of the substantive benefits. These include the opportunity for increased student engagement, access to, and awareness of, course and community related issues, and citizenship. The paper also identifies potential opportunities to incorporate the dimensions of participation and collaboration between institutions of higher learning and the community/world to mobilize knowledge and offer unique scholarship opportunities for faculty.
Effects of prolonged cerebrospinal fluid shunting on the skull and brain.

✓ A review of postoperative radiographs in hydrocephalic patients treated with ventriculojugular shunts reveals a marked decrease in the CSF fluid spaces, both subarachnoid and intraventricular, reflected in compensatory skull changes and alterations in ventricular configuration. Most of the changes appear to be reversible when shunt malfunction develops, with the exception of acquired synostosis. Exceptions to the generalized changes that can be expected in all cases include absence of changes in the sella turcica in the presence of an intact diaphragma sellae, persistence of the “right angle” sella turcica and concave basi-occiput in patients with an Arnold-Chiari Type II malformation, and shifts of the lateral ventricle when the septum pellucidum is intact. Experimental evidence in shunted hydrocephalic dogs suggests that differential damping of ventricular pulse pressure by the shunt is a factor.
Intelligent High-Performance Crawlers Used to Reveal Topic-Specific Structure of WWW

The slogan that "information is power" has undergone a slight change. Today, "information updating" is in the focus of interest. The largest source of information today is the World Wide Web. Fast search methods are needed to utilize this enormous source of information. In this paper our novel crawler using support vector classification and on-line reinforcement learning is described. We launched crawler searches from different sites, including sites that offer, at best, very limited information about the search subject. This case may correspond to typical searches of non-experts. Results indicate that the considerable performance improvement of our crawler over other known crawlers is due to its on-line adaptation property. We used our crawler to characterize basic topic-specific properties of WWW environments. It was found that topic-specific regions have a broad distribution of valuable documents. Expert sites are excellent starting points, whereas mailing lists can form trape for the crawler. These properties of the WWW and the emergence of intelligent "high-performance" crawlers that monitor and search for novel information together predict a significant increase of communication load on the WWW in the near future.
A machine learning based approach for predicting undisclosed attributes in social networks

Online Social Networks have gained increased popularity in recent years. However, besides their many advantages, they also represent privacy risks for the users. In order to control access to their private information, users of OSNs are typically allowed to set the visibility of their profile attributes, but this may not be sufficient, because visible attributes, friendship relationships, and group memberships can be used to infer private information. In this paper, we propose a fully automated approach based on machine learning for inferring undisclosed attributes of OSN users. Our method can be used for both classification and regression tasks, and it makes large scale privacy attacks feasible. We also provide experimental results showing that our method achieves good performance in practice.
On Linear Spaces of Polyhedral Meshes

Polyhedral meshes (PM)-meshes having planar faces-have enjoyed a rise in popularity in recent years due to their importance in architectural and industrial design. However, they are also notoriously difficult to generate and manipulate. Previous methods start with a smooth surface and then apply elaborate meshing schemes to create polyhedral meshes approximating the surface. In this paper, we describe a reverse approach: given the topology of a mesh, we explore the space of possible planar meshes having that topology. Our approach is based on a complete characterization of the maximal linear spaces of polyhedral meshes contained in the curved manifold of polyhedral meshes with a given topology. We show that these linear spaces can be described as nullspaces of differential operators, much like harmonic functions are nullspaces of the Laplacian operator. An analysis of this operator provides tools for global and local design of a polyhedral mesh, which fully expose the geometric possibilities and limitations of the given topology.
Dissimilarity-Based Algorithms for Selecting Structurally Diverse Sets of Compounds

This paper commences with a brief introduction to modern techniques for the computational analysis of molecular diversity and the design of combinatorial libraries. It then reviews dissimilarity-based algorithms for the selection of structurally diverse sets of compounds in chemical databases. Procedures are described for selecting a diverse subset of an entire database, and for selecting diverse combinatorial libraries using both reagent-based and product-based selection.