Miracle-dz/UniFAR-FTUs huggingface dataset:
How Can Japan Improve Relations with South Korea?

This article explores how the Abe administration might go about improving Japan's relationship with the South Korean government of President Park Geun-hye. Although bilateral ties are strained by disagreements over history, territory, and the “comfort women” issue, as well as mutual mistrust and “fatigue,” the paper argues that the two sides actually share substantial interests in common and urges Japanese leaders not to lose hope but to continue working hard to improve relations. It lays out a menu of policy “options” across political-diplomatic; security; economic; educational and socio-cultural; and environmental and scientific domains, and describes a strategy for how to build a better relationship over the next several years.
Consistent SMARCB1 homozygous deletions in epithelioid sarcoma and in a subset of myoepithelial carcinomas can be reliably detected by FISH in archival material

Epithelioid sarcomas (ES) are mesenchymal neoplasms subclassified into distal and proximal subtypes based on their distinct clinical presentations and histologic features. Consistent loss of SMARCB1 nuclear expression has been considered as the hallmark abnormality for both subtypes, a feature shared with atypical teratoid/rhabdoid tumor of infancy (ATRT). While virtually all ATRTs harbor underlying SMARCB1 somatic or germline alterations, mechanisms of SMARCB1 inactivation in ES are less well defined. To further define mechanisms of SMARCB1 inactivation a detailed molecular analysis was performed on 40 ES (25 proximal and 15 distal ES, with classic morphology and negative SMARCB1 expression) for their genomic status of SMARCB1 and related genes encoding the SWI/SNF subunits (PBRM1, BRG1, BRM, SMARCC1/2 and ARID1A) by FISH using custom BAC probes. An additional control group was included spanning a variety of 41 soft tissue neoplasms with either rhabdoid/epithelioid features or selected histotypes previously shown to lack SMARCB1 by IHC. Furthermore, 12 ES were studied by array CGH (aCGH) and an independent TMA containing 50 additional ES cases was screened for Aurora Kinase A (AURKA) and cyclin D1 immunoexpression. Homozygous SMARCB1 deletions were found by FISH in 36/40 ES (21/25 proximal‐type). One of the distal‐type ES displayed homozygous SMARCB1 deletion in the tumor cells, along with a heterozygous deletion within normal tissue, finding confirmed by array CGH. None of the proximal ES lacking homozygous SMARCB1 deletions displayed alterations in other SWI/SNF subunits gene members. Among controls, only the SMARCB1‐immunonegative myoepithelial carcinomas displayed SMARCB1 homozygous deletions in 3/5 cases, while no gene specific abnormalities were seen among all other histologic subtypes of sarcomas tested regardless of the SMARCB1 protein status. There was no consistent pattern of AURKA and Cyclin D1 expression. The array CGH was successful in 9/12 ES, confirming the SMARCB1 and other SWI/SNF genes copy numbers detected by FISH. Our study confirms the shared pathogenesis of proximal and distal ES, showing consistent SMARCB1 homozygous deletions. Additionally we report the first ES case associated with a SMARCB1 constitutional deletion, establishing a previously undocumented link with ATRT. Alternative mechanisms of SMARCB1 inactivation in SMARCB1‐disomic ES remain to be identified, but appear unrelated to large genomic abnormalities in other SWI/SNF subunits. © 2014 Wiley Periodicals, Inc.
Multilingual Speech Databases at LDC

As multilingual products and technology grow in importance, the Linguistic Data Consortium (LDC) intends to provide the resources needed for research and development activities, especially in telephone-based, small-vocabulary recognition applications; language identification research; and large vocabulary continuous speech recognition research.The POLYPHONE corpora, a multilingual "database of databases," are specifically designed to meet the needs of telephone application development and testing. Data sets from many of the world's commercially important languages will be available within the next few years.Language identification corpora will be large sets of spontaneous telephone speech in several languages with a wide variety of speakers, channels, and handsets. One corpus is now available, and current plans call for corpora of increasing size and complexity over the next few years.Large vocabulary speech recognition requires transcribed speech, pronouncing dictionaries, and language models. To fill this need, LDC will use the unattended computer-controlled collection methods developed for SWITCH-BOARD to create several similar corpora, each about one-tenth the size of SWITCHBOARD, in other languages. Text corpora sufficient to create useful language models will be collected and distributed as well. Finally, pronouncing dictionaries covering the vocabulary of both transcripts and texts will be produced and made available.
Dichotomy of astrocytoma migration and proliferation

Astrocytomas often show high rates of local invasion that lead to local recurrence of the disease. Histologically, the most highly invasive astrocytoma cells are detected in isolation rather than as nests of tumor. Our study attempted to determine whether the migratory response to extracellular substrates influences the proliferative behavior of these highly invasive cells. The preferential and specific migratory response of human astrocytoma cells to extracellular matrix proteins was assessed by a microliter scale migration assay. Growth curve studies on protein ligands permissive (merosin) for cell migration indicated that the lag phase was protracted compared with cells seeded on non‐permissive proteins (vitronectin). Once a certain cell density was reached, logarithmic proliferation was indistinguishable on the different proteins. The proliferation index of populations of cells migrating on merosin and vitronectin was measured by both BrdU incorporation and MIB‐I immunocytochemistry labeling. Cells seeded on vitronectin showed higher proliferation throughout the population than cells seeded on merosin. On merosin, the more migratory cells at the periphery were less proliferative than non‐migratory cells in the central region of that population. The integrin‐associated signal transduction protein, p125FAK, was heavily localized in the membrane of non‐migrating cells and largely absent in migrating astrocytoma cells. We conclude that temporally, proliferation and migration are mutually exclusive behaviors. Cell density or non‐permissive substrates that inhibit cell motility favor a more proliferative phenotype. Conversely, active migration suppresses cell proliferation. © 1996 Wiley‐Liss, Inc.
AN ECONOMETRIC ANALYSIS OF OIL/NON-OIL SECTORS AND ECONOMIC GROWTH IN THE GCC: EVIDENCE FROM SAUDI ARABIA AND THE UAE

As a depletable resource oil is a useful source of economic growth, but may not be relied upon for long-term sustainable development. Diversification from oil is needed to achieve this. This research applies three models to examine the most important determinants of oil and non-oil sector economic growth in two of the largest economies in the Gulf Cooperation Council (GCC), namely Saudi Arabia and the UAE. The empirical analysis applies the Johansen approach and ECM to access the relationship between all variables, both in the long and short-term. Given the governments’ determination to reduce dependence on oil income, this study focuses on the role of non-oil sectors. Explanatory variables in the models included exports, government spending, investment (private and public), tourism (religious and international), labour and capital, while GDP is used as the dependent variable. The results reflect the fact that the main determinants of economic growth in Saudi Arabia are related to the oil sector. The analysis of the long-term relationship between selected variables in the main model find that total exports have the greatest influence on economic growth, while tourism is the least influential variable. Moreover, empirical results show that all variables are important in the growth of the Saudi economy except non-oil exports. The role of religious tourism is not found to be significant in the process of economic growth when the economy as a whole is taken into consideration. Nonetheless, when isolating the non-oil sectors, the effect of religious tourism has a greater influence on economic growth. Concrete evidence also exists as to the II importance of the role of an additional variable – government spending – in enhancing
A Novel SVM and Its Application to Breast Cancer Diagnosis

This paper presents a novel method of improving the performance of a support vector machine (SVM) classifier by modifying kernel function. This is based on the differential approximation of metric. The method is to enlarge margin around the separating hyper-plane by modifying the kernel functions using a positive scalar function. Therefore, the separability is increased. Example is given specifically for modifying Gaussian Radial Basis Function kernel. Simulation results for both artificial and real data show remarkable improvement of generalization error and computational cost.
The prognostic value of positron emission tomography performed after two courses (INTERIM‐PET) of standard therapy on treatment outcome in early stage Hodgkin lymphoma: A multicentric study by the fondazione italiana linfomi (FIL)

This retrospective study included 246 patients with a new diagnosis of Hodgkin Lymphoma (HL) with a localized‐stage (IA‐IIA), consecutively admitted from January 2002 to December 2008, by twelve Italian hematological centers on behalf of Fondazione Italiana Linfomi (FIL).
Early Experiences and Clinical Implications of Drug-Eluting Stents: Part 1

OBJECTIVE To review the pathogenesis of in-stent restenosis and the evolution of drug-eluting stents (DES). DATA SOURCES Using the search terms sirolimus, paclitaxel, and drug-eluting stents, a literature review was conducted to identify peer-reviewed articles and abstracts in MEDLINE (1966—June 2003). Recent meeting abstracts were accessed through the American Heart Association and the American College of Cardiology Web sites. Citations from available articles were also reviewed for additional references. STUDY SELECTION AND DATA EXTRACTION Published reviews and studies showing the effects of in-stent restenosis and drug-coated and -eluting stents were evaluated and reviewed. DATA SYNTHESIS Coronary stent implantation is a common form of percutaneous coronary interventions. Approximately 20–30% of patients undergoing stent placement develop restenosis 6 months after the procedure. The primary cause of in-stent restenosis is neointimal proliferation and subsequent accumulation of extracellular matrix, collagen, and macrophages. Eluting stents with an antimitotic agent may reduce the extent of restenosis. Research is ongoing in terms of finding the ideal combination of antimitotic agent, stent, and eluting medium to create the perfect stent. CONCLUSIONS Research over the last decade has led to a better understanding of the pathogenesis of in-stent restenosis and ways to prevent restenosis. DES are being developed as one of the strategies to prevent restenosis.
Nano Hydroxyapatite-coated Implants Improve Bone Nanomechanical Properties

Nanostructure modification of dental implants has long been sought as a means to improve osseointegration through enhanced biomimicry of host structures. Several methods have been proposed and demonstrated for creating nanotopographic features; here we describe a nanoscale hydroxyapatite (HA)-coated implant surface and hypothesize that it will hasten osseointegration and improve its quality relative to that of non-coated implants. Twenty threaded titanium alloy implants, half prepared with a stable HA nanoparticle surface and half grit-blasted, acid-etched, and heat-treated (HT), were inserted into rabbit femurs. Pre-operatively, the implants were morphologically and topographically characterized. After 3 weeks of healing, the samples were retrieved for histomorphometry. The nanomechanical properties of the surrounding bone were evaluated by nanoindentation. While both implants revealed similar bone-to-implant contact, the nanoindentation demonstrated that the tissue quality was significantly enhanced around the HA-coated implants, validating the postulated hypothesis.
Effects of Animal-Assisted Activities with Guinea Pigs in the Primary School Classroom

ABSTRACT This study investigated the effects of a classroom-based animal-assisted activities (AAA) program with guinea pigs on the social functioning of primary school children. We hypothesized that participants in the experimental condition (n = 64), compared with a waitlist control group (n = 64), would demonstrate improvements in social functioning following the program. Parents and teachers used the Social Skills Rating System (SSRS) to evaluate the social skills and problem behaviors of 128 participating children (age range = 4.8 to 12.7 years) before and after an 8-week period. Teachers also rated academic competence at both time points. Children who participated in the AAA program demonstrated significantly greater improvements in social functioning than their control group peers, as defined by greater increases in social skills (teacher SSRS) and decreases in problem behaviors (parent and teacher SSRS). There were no significant differences between the groups in academic competence. AAA participants demonstrated significant increases in social skills and decreases in problem behaviors from pre- to post-program on the teacher version of the SSRS. Control group participants did not show significant changes on these measures. These findings suggest that an AAA program with guinea pigs may be a feasible addition to the primary school classroom in order to improve social functioning. Further component analysis will be necessary to determine whether the animal is the active ingredient in AAA programs of this nature.
A stimulus for affirmative action? The impact of the American Recovery and Reinvestment Act on women and minority workers in construction

PREFACE This working paper is one of a collection of papers, most of which were prepared for and presented at a fest-schrift conference to honor the life's work of Professor Since the early 1970s, Tom Weisskopf has been challenging the foundations of mainstream economics and, still more fundamentally, the nature and logic of capitalism. That is, Weisskopf began putting capitalism on trial over 40 years ago. He rapidly established himself as a major contributor within the newly emerging field of radical economics and has remained a giant in the field ever since. The hallmarks of his work are his powerful commitments to both egalitarianism as a moral imperative and rigorous research standards as a means. We chose the themes and contributors for this working paper series, and the upcoming festschrift, to reflect the main areas of work on which Tom Weisskopf has focused, with the aim of extending research in these areas in productive new directions. The series is divided into eight sections, including closing reflections by our honoree himself, Professor Weisskopf. Each section except for the last includes comments by discussants as well as the papers themselves.
3D cartography of light scattered by plasmonic nanostructures at resonance obtained by digital heterodyne holography

Nanoantennas are the direct extension of conventional radio and microwave antennas to the visible frequency range and can be used to convert optical radiation into localized energy and resonantly enhance light scattering [1,2]. Here, we present a highly sensitive full-field imaging technique based on digital heterodyne holography [3] which allows the measurement of both amplitude and phase. This results in the 3D mapping of light scattered by plasmonic nanostructures at specific resonance wavelengths. Spectral and spatial properties of the field are compared to numerical simulations.
Title Impact of pumped storage on power systems with increasingwind penetration

In this paper, the unit commitment and dispatch of a power system with and without a pumped storage unit is examined for increasing levels of installed wind power, from 17% of total energy to 80% of total energy generated by wind 3 (3GW to 15GW of installed wind on the Irish system in 2020). At high levels of installed wind, it is shown that storage reduces curtailment and increases the use the base loaded plant on the system. This reduces system costs. However, when the additional capital costs of storage are taken into account, it is shown that storage is not viable from a system perspective until extremely large levels of wind power are seen on the system. At these levels of installed wind, while the system can operate without storage, it is less costly to do so with storage. The capacity credit of the storage unit is also examined, using a simplified approach, and shown to decrease as larger amounts of intermittent wind power are added to the system.
Human Parvovirus B19-Induced Acute Glomerulonephritis: A Case Report

Human parvovirus B19 (HPV B19) infection is well known as a cause of erythema infectiosum in children. Acute glomerulonephritis due to HPVB19 infection is rarely observed in adults. Here, we present the case of a 45-year-old female who showed acute glomerulonephritis induced by HPVB19 infection with various autoantibodies. She had proteinuria (175 mg/g creatinine) and hematuria (20–29 erythrocytes per high-power field) in a urinalysis, and various autoantibodies such as antinuclear antibodies, proteinase-3-antineutrophil cytoplasmic antibodies (PR3-ANCA), antiglomerular basement membrane (GBM) antibodies, and anticardiolipin antibodies in a blood examination. A renal biopsy showed that endocapillary proliferative glomerulonephritis comprised of mononuclear cell infiltration. By using immunofluorescence microscopy, IgG, IgA, IgM, C3, C4, and C1q deposits were detected mainly in glomerular capillaries. Electron-dense deposits were detected in the subendothelial area and mesangial area by using electron microscopy. All symptoms and abnormal laboratory data were self-improved. Our patient’s case may provide a clue to the etiology of ANCA-associated vasculitis or lupus nephritis.
Cross-Race Misaggregation: Its Detection, a Mathematical Decomposition, and Simpson’s Paradox

Researchers sometimes aggregate data, such as combining resident data into state-level means. Doing so can sometimes cause valid individual-level data to be invalid at the group level. We focus on cross-race misaggregation, which can occur when individual-level data are confounded with race. We discuss such misaggregation in the context of Simpson’s Paradox and identify 4 diagnostic indicators: aggregated rates that correlate strongly with the relative size of one or more subgroup(s), unequal sample sizes across subgroups, unequal rates or mean values across subgroups, and aggregated rates that do not correlate with subgroup rates. To illustrate these diagnostic indicators, we decomposed data on the prevalence of sexually transmitted diseases (STDs) to confirm cross-race misaggregation in Parasite Stress U.S.A. , an ostensible index of parasite prevalence known to be confounded with the proportion of African American residents per state.
Iterative GRAPPA (iGRAPPA) for improved parallel imaging reconstruction

In this work an iterative reconstruction method based on generalized autocalibrating partially parallel acquisitions (GRAPPA) reconstruction is introduced. In the new method the reconstructed lines are used to reestimate and refine the weights from all the acquired data by applying the GRAPPA procedure iteratively with regularization. Both phantom and in vivo MRI experiments demonstrated that, compared to GRAPPA, the iterative approach reduces parallel imaging artifacts and permits high‐quality image reconstruction with a relatively small number of calibration lines and slight changes of GRAPPA weights. Magn Reson Med 59:903–907, 2008. © 2008 Wiley‐Liss, Inc.
Ultrasonography and Lung Mechanics Can Diagnose Diaphragmatic Paralysis Quickly

Diaphragmatic paralysis after cardiovascular surgery requires early diagnosis prior to extubation. The effectiveness of ultrasonography and a lung mechanics assessment was evaluated. Paralysis of the diaphragm was diagnosed when the diaphragm failed to move or moved in a cephalad direction during inspiration. It was diagnosed in 3 of 40 patients (7.5%) who underwent cardiovascular surgery from 1998 to 1999. Patients were extubated when all parameters met the extubation criteria, irrespective of the presence or absence of diaphragmatic paralysis. One patient required prolonged assisted ventilation and died from mediastinitis on the 35th postoperative day. The other 2 patients required assisted ventilation for an additional 1–3 days. Ultrasonography and a lung mechanics assessment are effective tools for the early diagnosis of diaphragmatic paralysis and assessment of respiratory function after cardiovascular surgery.
Parents' difficulties and information needs in coping with acute illness in preschool children: a qualitative study

Abstract Objectives: To identify and explore difficulties parents experience with acute illness in young children and the information they seek to help them. Design: Qualitative study using semistructured one to one and group interviews with parents of preschool children. Setting: Disadvantaged inner city community. Subjects: 95 parents of preschool children. Results: Parents felt disempowered when dealing with acute illness in their children because of difficulties making sense of the illness. Central to parents' difficulties were their experiences of inadequate information sharing by their general practitioners and variations in their doctors' decisions and behaviour. Disparity between parents' beliefs and expectations about illness and treatment and professionals' behaviour further frustrated parents' attempts to understand illness. Parents expressed a need for a range of accessible and specific information to support them through their negotiation of children's illness. Conclusions: Communication with parents requires greater recognition of parents' difficulties. Professionals have considerable potential to empower parents by sharing more information and skills. Such information should be consistent and address parents' concerns, beliefs, and expressed needs if this potential is to be realised. Key messages Greater recognition of parents' difficulties may help to reduce potential disharmony between par- ents and doctors Attempts to share greater and consistent information may empower parents and should be sensitive to parents' concerns, beliefs, and needs Tensions may arise for both parents and doctors if greater sharing of knowledge is accompanied by difficulties in tolerating and sharing uncertainty
A new equivalent circuit model of IGBT for simulation of current sensors

A new equivalent circuit model for insulated gate bipolar transistor is presented. It takes into account both electron and hole conduction in sensors and is incorporated with SPICE3 for the simulation of three types of current sensors, namely active, bipolar, and MOS sensors. It adopts a multiMOS model to include the doping variation in the MOS body. The results agree well with the current sensing measurements within an average error of 4.4%.