Miracle-dz/UniFAR-FTUs huggingface dataset:
Overview of methods used to evaluate the adequacy of nutrient intakes for individuals and populations

The objective of the present paper is to review the methods of measuring micronutrient intake adequacy for individuals and for populations in order to ascertain best practice. A systematic review was conducted to locate studies on the methodological aspects of measuring nutrient adequacy. The results showed that for individuals, qualitative methods (to find probability of adequacy) and quantitative methods (to find confidence of adequacy) have been proposed for micronutrients where there is enough data to set an average nutrient requirement (ANR). If micronutrients do not have ANR, an adequate intake (AI) is often defined and can be used to assess adequacy, provided the distribution of daily intake over a number of days is known. The probability of an individual's intake being excessive can also be compared with the upper level of safe intake and the confidence of this estimate determined in a similar way. At the population level, adequacy can be judged from the ANR using the probability approach or its short cut – the estimated average requirement cut-point method. If the micronutrient does not have an ANR, adequacy cannot be determined from the average intake and must be expressed differently. The upper level of safe intake can be used for populations in a similar way to that of individuals. All of the methodological studies reviewed were from the American continent and all used the methodology described in the Institute of Medicine publications. The present methodology should now be adapted for use in Europe.
RestoCut: Reconstruction of regular images using graph cuts

In this paper new approach to reconstruct images, removing unwanted objects from it, is described. The main idea of the introduced approach is to generate texture over unwanted object using graph cut based texture synthesis algorithm. Different texture synthesis techniques are briefly covered, while used technique is described in detail. After that, migration from the texture synthesis problem to the image reconstruction problem is explained, and some experimental results are shown.
Multivariable nonlinear model reference control of cement mills

This paper presents a method for model reference control of a cement milling circuit that has previously been studied several times. The approach presented is based on an experimentally justified model of a cement milling circuit. We derive the form of the control vector with the goal of driving the response of the system to that of a desired model in a noisy operating environment. The paper demonstrates the selection of the reference dynamics and the derivation of the control laws. The approach is based on the Lyapunov theory, and the results observed justify the tracking and stability claims of the paper.
Periodicity coding in the inferior colliculus of the cat. I. Neuronal mechanisms.

1. Temporal properties of single- and multiple-unit responses were investigated in the inferior colliculus (IC) of the barbiturate-anesthetized cat. Approximately 95% of recording sites were located in the central nucleus of the inferior colliculus (ICC). Responses to contralateral stimulation with tone bursts and amplitude-modulated tones (100% sinusoidal modulation) were recorded. Five response parameters were determined for neurons at each location: 1) characteristic frequency (CF); 2) onset latency of responses to CF-tones 60 dB above threshold; 3) Q10 dB (CF divided by bandwidth of tuning curve 10 dB above threshold); 4) best modulation frequency for firing rate (rBMF or BMF; amplitude modulation frequency that elicited the highest firing rate); and 5) best modulation frequency for synchronization (sBMF; amplitude modulation frequency that elicited the highest degree of phase-locking to the modulation frequency). 2. Response characteristics for single units and multiple units corresponded closely. A BMF was obtained at almost all recording sites. For units with a similar CF, a range of BMFs was observed. The upper limit of BMF increased approximately proportional to CF/4 up to BMFs as high as 1 kHz. The lower limit of encountered BMFs for a given CF also increased slightly with CF. BMF ranges for single-unit and multiple-unit responses were similar. Twenty-three percent of the responses revealed rBMFs between 10 and 30 Hz, 51% between 30 and 100 Hz, 18% between 100 and 300 Hz, and 8% between 300 and 1000 Hz. 3. For single units with modulation transfer functions of bandpass characteristics, BMFs determined for firing rate and synchronization were similar (r2 = 0.95). 4. Onset latencies for responses to CF tones 60 dB above threshold varied between 4 and 120 ms. Ninety percent of the onset latencies were between 5 and 18 ms. A range of onset latencies was recorded for different neurons with any given CF. The onset response latency of a given unit or unit cluster was significantly correlated with the period of the BMF and the period of the CF (P less than 0.05). 5. "Intrinsic oscillations" of short duration, i.e., regularly timed discharges of units in response to stimuli without a corresponding temporal structure, were frequently observed in the ICC. Oscillation intervals were commonly found to be integer multiples of 0.4 ms. Changes of stimulus frequency or intensity had only minor influences on these intrinsic oscillations. (ABSTRACT TRUNCATED AT 400 WORDS)
2 0 A ug 2 00 2 Relativistic Doppler Effect in Quantum Communication

When an electromagnetic signal propagates in vacuo, a polarization detector cannot be rigorously perpendicular to the wave vector because of diffraction effects. The vacuum behaves as a noisy channel, even if the detectors are perfect. The " noise " can however be reduced and nearly cancelled by a relative motion of the observer toward the source. The standard definition of a reduced density matrix fails for photon polarization , because the transversality condition behaves like a superselection rule. We can however define an effective reduced density matrix which corresponds to a restricted class of positive operator-valued measures. There are no pure photon qubits, and no exactly orthogonal qubit states.
Compiler-optimized usage of partitioned memories

In order to meet the requirements concerning both performance and energy consumption in embedded systems, new memory architectures are being introduced. Beside the well-known use of caches in the memory hierarchy, processor cores today also include small onchip memories called scratchpad memories whose usage is not controlled by hardware, but rather by the programmer or the compiler. Techniques for utilization of these scratchpads have been known for some time. Some new processors provide more than one scratchpad, making it necessary to enhance the workflow such that this complex memory architecture can be efficiently utilized. In this work, we present an energy model and an ILP formulation to optimally assign memory objects to different partitions of scratchpad memories at compile time, achieving energy savings of up to 22% compared to previous approaches.
Treatment of pemphigus vulgaris with brief, high-dose intravenous glucocorticoids.

OBJECTIVES To determine if intravenous high-dose "pulse" glucocorticoid therapy induced remission or reduced subsequent requirements for orally administered glucocorticoids in pemphigus vulgaris. DESIGN Retrospective, case-controlled study. SETTING Academic referral center. PATIENTS OR OTHER PARTICIPANTS Fifteen patients, all of whom had pemphigus vulgaris, were included in the analysis. The group comprised all patients with pemphigus vulgaris seen during 11.5 years who did not initially respond to low doses (< 40 mg/d) of prednisone and who were followed up for at least 500 days after beginning treatment. INTERVENTIONS One group received very high-dose intravenous pulse(s) of methylprednisolone sodium succinate (Solu-Medrol) (n = 9). The other group did not receive intravenous pulse therapy (n = 6). MAIN OUTCOME MEASURES Glucocorticoid dose and status of disease. RESULTS Patients treated with pulse therapy and control patients treated with conventional oral prednisone had similar initial disease severity. Six of the 9 patients who received pulse therapy showed improvement of their pemphigus vulgaris, and 4 of the 9 had discontinued all glucocorticoids and were in remission at mean (+/- SEM) 269 +/- 27 days. They have continued in remission without receiving prednisone for a mean of 714 +/- 142 days. Therapeutic benefit was seen in patients who received pulse therapy early or late after beginning glucocorticoid therapy. In contrast, none of the 6 control patients has achieved long-term remissions without therapy. All of the controls have had long courses of glucocorticoid therapy, with a mean of 1467 +/- 112 days of prednisone treatment. Overall, the mean (+/- SEM) prednisone dose between days 350 and 500 from onset of glucocorticoid therapy was 9.2 +/- 4.2 mg/d for those who received pulse therapy vs 21.0 +/- 3.3 mg/d (P < .05) for those who did not (unpaired 2-tailed t test). CONCLUSIONS High-dose pulse administration of glucocorticoids is a potentially effective therapy to be considered in the treatment of patients with severe pemphigus vulgaris. Similar patients treated with conventional orally administered doses of prednisone had protracted courses requiring years of glucocorticoid therapy with no long-term remissions.
A Method for Record Linkage with Sparse Historical Data

Massive digitization of archival material, coupled with automatic document processing techniques and data visualisation tools offers great opportunities for reconstructing and exploring the past. Unprecedented wealth of historical data (e.g. names of persons, places, transaction records) can indeed be gathered through the transcription and annotation of digitized documents and thereby foster large-scale studies of past societies. Yet, the transformation of hand-written documents into well-represented, structured and connected data is not straightforward and requires several processing steps. In this regard, a key issue is entity record linkage, a process aiming at linking different mentions in texts which refer to the same entity. Also known as entity disambiguation, record linkage is essential in that it allows to identify genuine individuals, to aggregate multi-source information about single entities, and to reconstruct networks across documents and document series. In this paper we present an approach to automatically identify coreferential entity mentions of type Person in a data set derived from Venetian apprenticeship contracts from the early modern period (16th-18th c.). Taking advantage of a manually annotated sub-part of the document series, we compute distances between pairs of mentions, combining various similarity measures based on (sparse) context information and person attributes.
Effect of Nilvadipine on the Development of Neurological Deficits in Stroke‐Prone Spontaneously Hypertensive Rats

Background and Purpose Several types of antihypertensive drugs have been reported to protect stroke-prone spontaneously hypertensive rats from stroke. However, the clinical relevance remains unclear. This study was performed to investigate the effect of nilvadipine, a calcium channel blocker, on the development of neurological deficits in stroke-prone spontaneously hypertensive rats. In addition, plasma levels of nilvadipine were measured to determine the clinical relevance. Methods Salt-loaded stroke-prone spontaneously hypertensive rats were orally administered nilvadipine mixed with a powder diet (0.01% and 0.03%, wt/wt). Non-salt-loaded rats were maintained on tap water. Chronological changes in neurological deficit scores and systolic blood pressure were recorded. After 6 weeks of medication, measurement of plasma levels of nilvadipine, serum biochemical analysis, and pathological observation of both the brain and the kidney were performed. Results In the salt-loaded control group, both severe hypertension and neurological deficit developed, and the final survival rate was 30%. Systolic blood pressure decreased significantly in the high-dose nilvadipine-treated group but not in the low-dose nilvadipine-treated group. However, the development of neurological deficit was almost completely inhibited in both nilvadipine-treated groups that had no deaths (F<.01). The mean plasma levels of nilvadipine in the low- dose group and in the high-dose group at the time of death were 0.21 ng/mL and 0.61 ng/mL, respectively. Conclusions Nilvadipine inhibited the development of neurological deficit in stroke-prone spontaneously hypertensive rats at plasma concentrations lower than that in clinical use. Thus, nilvadipine might prevent cerebral vascular disorders at doses routinely used for essential hypertension.
Laminar and retinotopic organization of the macaque lateral geniculate nucleus: Magnocellular and parvocellular magnification functions

The laminar morphology and electrophysiologically determined retinotopic organization of a single rhesus macaque lateral geniculate nucleus (LGN) were reconstructed on series of coronal, sagittal, and horizontal cuts through a three‐dimensional computer representation of the nucleus. Neurons were counted in this same nucleus, allowing the magnification functions (cells/degree2 as functions of eccentricity) of magnocellular and parvocellular layers to be determined after eliminating the effects of nonuniform volume shrinkage. Parvocellular magnification was approximately 10,000 times higher in the foveola than in the far periphery. On average, magnocellular neurons made up 2.6% of the LGN in the central 2 degrees (but probably a smaller fraction in the central fovea). The magnocellular portion increased steadily with eccentricity to 27% in the far periphery. Thus the magno/parvo ratio increases from foveola to far periphery by a factor of at least 14. The parvocellular magnification function matches estimates of cortical magnification, whereas the density of magnocellular afferents to cortex increases monotonically with eccentricity. At the posterior pole of the nucleus, the numbers of layers are reduced through a fusion of two layers and the disappearance of one or two others, a feature that may be associated with the foveal ipsilateral hemifield representation. © 1996 Wiley‐Liss, Inc.
Adaptación y validación del ITQ (Interpersonal Trust Questionnaire). Una nueva medida del apoyo social Adaptation and validation of the ITQ (Interpersonal Trust Questionnaire). A new measure of social support

The present paper reports on the results of the Spanish adaptation and validation of the Interpersonal Trust Questionnaire (ITQ – Forbes & Roger, 1999), conducted with a sample of Venezuelan college students. The original 48 items scale measures the capacity of individuals to use social support effectively, trough three different dimensions: Fear of disclosure (FOD), Social coping (SC) and Social intimacy (SI). The scale, jointly with other personality questionnaires, was administered to a sample of 292 university students from three different universities in Caracas-Venezuela. Results from the factor analysis resembled only two of the three dimensions of the questionnaire, comprising 46 items with high internal consistencies in each. The concurrent validity study showed the dimensions to be related in the expected way, while the predictive validity study conducted with a different sample of 328 unemployed people revealed the fear of disclosure to be positively related to a poor general health status and the social coping to be protective of the individual’s psychological health.
Frontal lobe dysfunctions in patients with juvenile myoclonic epilepsy

Abstract Juvenile myoclonic epilepsy (JME) is a common form of idiopathic generalized epilepsy. Behavioral and cognitive problems are frequently observed in JME. Although the underlying mechanisms are still unknown, recent neuropsychological and neuroimaging studies provide strong evidence for frontal lobe dysfunction. Neuropsychological studies have shown JME patients to be impaired in a number of executive functions such as concept formation, abstract reasoning, mental flexibility, and cognitive speed and planning. They scored below average on measures of attention, immediate verbal memory, working memory, and verbal fluency. The patients with JME performed worse than the group with temporal lobe epilepsy on some frontal tasks. Some specific personality features, such as unreliability and emotional instability, poor social adjustment, high rates of anxiety, mood disorders, phobias and somatization disorders seen in patients with JME have also been described in patients with frontal lobe-lesions. Quantitative magnetic resonance imaging studies have shown regional, frontal cortical and thalamic grey matter abnormalities. These findings support the pathophysiological concept of functional abnormalities in the thalamo-cortical circuit in JME. The additional impact of interictal epileptiform electroencephalography activity on cognitive functions was suggested. Poor working memory and impaired executive and motor performance in JME patients may also be attributed to altered dopamine signaling in the striatum and frontal lobes. JME may be a non-uniform condition. Different genetic and pathophysiologic mechanisms could underlie the clinically observed differences in prognosis, cognitive functioning, personality traits, and frontal lobe deficits.
Audio/video fusion for objects recognition

In mobile robotics applications, pattern and object recognition are mainly achieved relying only on vision. Several other perceptual modalities are also available such as, touch, hearing or vestibular proprioception. They are rarely used and can provide valuable additional information within the recognition tasks. This article presents an analysis of several methods of fusion of perceptual and auditory modalitites. It relies on the use of a perspective camera and a microphone on a moving object recognition problem. Experimental data are also provided on a database of audio/visual objects including cases of visual occlusions and audio corruptions.
Adenosine in Myocardial Protection given through Three Windows of Opportunity. An Experimental Study with Pigs

Objective –Adenosine (ADO) has been shown to have beneficial effects against tissue injury after myocardial ischemia. However, the timing and dose of ADO administration have not been defined. This study was designed to determine the cardioprotective effect of exogenous ADO in an experimental open heart surgery model in pigs. Design –The animals were openly divided into two groups both undergoing 30 min of total cardiac arrest. In the control group animals received cold crystalloid cardioplegic solution. In the ADO group ADO was added to cardioplegic solution and in addition ADO was infused to the superior vena cava for 2 h starting 30 min before cardiac arrest. The pumping function of the heart was measured with echocardiography and myocardial blood flow was measured with microspheres and positron emission tomography (PET). Cardiomyocyte apoptosis was detected and tumor necrosis factor (TNF) levels were measured. Results –Better post-ischemic pumping function was found in the ADO group (relative decrease 43.7% vs 55.4%, p = 0.20 between the groups). The cardiac output decreased significantly from the baseline values ( p < 0.05 in both groups). There was a temporary decrease in myocardial blood flow post-ischemically, followed by a compensatory increase during the later reperfusion period. The cardiomyocyte apoptosis was induced significantly in both groups. Conclusions –In this experiment two important details were noticed. Firstly, cardiomyocyte apoptosis is involved in ischemia-reperfusion injury associated with open heart surgery. Secondly, PET is a comparable method with the microsphere technique when coronary flow is studied. No significant effects of ADO against ischemia-reperfusion injury could be shown. However, there were some signs of positive outcome, even though statistical significance could not be reached.
Parametric Brain MR Atlases: Standardization for Imaging Informatics

This paper is focused on the development of normal MR brain atlases of intrinsic MR parameters. These parameters permit quantitative comparisons across imaging studies (as opposed to raw image intensity values) and are important markers of neurological diseases. The development includes fast sequences to generate three parameters (T1: spin-lattice relaxation, T2: spin-spin relaxation, and Diffusion Tensor) covering the whole brain with isotropic and high-resolution images. The analysis of raw data to generate the parametric images is followed by registration algorithms to bring the image studies acquired on normal subjects aligned to a common frame of reference. The registration method includes both linear and non-linear algorithms. Two atlas schemes are discussed: an average atlas and a probabilistic atlas. Initial results on sequence development and registration are presented. The atlases are envisaged as an integral part of an imaging informatics infrastructure that enables image analysis across imaging studies to perform automated image data mining.
ACOUSTIC SCENE CLASSIFICATION USING CONVOLUTIONAL RECURRENT NEURAL NETWORKS

This paper presents an application of a convolutional recurrent neural network (CRNN) for the task of acoustic scene classification (ASC). Convolutional layers of CRNN are used as high-level feature extractors and gated recurrent layers are used to model the long term temporal context of the acoustic samples. The developed methods are evaluated using the 2017 edition of the ”Detection and Classification of Acoustic Scenes and Events” (DCASE) challenge task 1 and consequently tested on the datasets provided for the task of ASC. In this paper, we use two CRNN-based methods which score an overall accuracy of 78.9% and 80.8% compared to baseline feed-forward neural network with 74.8% accuracy.
Uncomplicated Resistance Training and Health-Related Outcomes: Evidence for a Public Health Mandate

Compared to aerobic training (AT), resistance training (RT) has received far less attention as a prescription for general health. However, RT is as effective as AT in lowering risk for cardiovascular disease, diabetes, and other diseases. There is a clear ability of RT, in contrast to AT, to promote gains, maintenance, or slow loss of skeletal muscle mass/strength. Thus, as an antisarcopenic exercise treatment, RT is of greater benefit than AT; given the aging of our population, this is of primary importance. In our view, a substantial barrier to greater adoption of RT is the incorrectly perceived importance of variables such as external load, intensity, and volume, leading to complex, difficult-to-follow regimes. We propose a more feasible and easier-to-adhere-to paradigm for RT that could affect how RT is viewed and adopted as a prescription for public health.
A combination of feedforward and feedback for the control of the nonlinear benchmark Inertia Wheel Pendulum

This contribution is about the combination of a feedforward and feedback controller in order to force a nonlinear plant along a sufficiently smooth reference curve. This approach includes a feedforward part in the framework of Port-Controlled Hamiltonian Systems with Dissipation (PCHD systems). PCHD systems have turned out beneficially for the design of nonlinear controllers and provide special properties for the stability analysis of equilibrium points. By means of feedback control one may overcome model errors and disturbances for a real application. A passivity-based controller, which is designed for the PCHD error dynamics, exploits the mathematical structure of the system and forces the tracking error to zero. The combination of the feedforward and feedback part leads to a controller, which achieves good tracking behavior, cancels initial errors and rejects disturbances from the environment. The derivation of a control law which includes a feedforward part and a feedback controller will be shown for the nonlinear underactuated benchmark example Inertia Wheel Pendulum.