Miracle-dz/UniFAR-FTUs huggingface dataset:
Robust Time Delay Estimation Based Intelligent PID Control of a 6DOF Upper-Limb Exoskeleton Robot

This paper will focus on a 6DOF upper-limb powered exoskeleton of healthy people or disabled people as the research object. After analyzing the human body physiological structure, this paper puts forward its own upper-limb powered exoskeleton model and designes a complete mechanical structure using SolidWorks. Then, it carries out a thorough analysis on the selected upper-limb powered exoskeleton model, using D-H matrix to establish the corresponding kinematics model; After that, this paper proposes robust time delay estimation based intelligent PID controllers (TDE-iPIDs) to control this exoskeleton model, which has simple structures, easy to adjust control parameters and strong ability to resist uncertainty. Then, this paper establishes a virtual prototype and imported it into MATLAB/SimMechanics to do simulation. Finally, the simulation results are given out.
Novel mRNA Targets for Tristetraprolin (TTP) Identified by Global Analysis of Stabilized Transcripts in TTP-Deficient Fibroblasts

ABSTRACT Tristetraprolin (TTP) is a tandem CCCH zinc finger protein that was identified through its rapid induction by mitogens in fibroblasts. Studies of TTP-deficient mice and cells derived from them showed that TTP could bind to certain AU-rich elements in mRNAs, leading to increases in the rates of mRNA deadenylation and destruction. Known physiological target mRNAs for TTP include tumor necrosis factor alpha, granulocyte-macrophage colony-stimulating factor, and interleukin-2β. Here we used microarray analysis of RNA from wild-type and TTP-deficient fibroblast cell lines to identify transcripts with different decay rates, after serum stimulation and actinomycin D treatment. Of 250 mRNAs apparently stabilized in the absence of TTP, 23 contained two or more conserved TTP binding sites; nine of these appeared to be stabilized on Northern blots. The most dramatically affected transcript encoded the protein Ier3, recently implicated in the physiological control of blood pressure. The Ier3 transcript contained several conserved TTP binding sites that could bind TTP directly and conferred TTP sensitivity to the mRNA in cell transfection studies. These studies have identified several new, physiologically relevant TTP target transcripts in fibroblasts; these target mRNAs encode proteins from a variety of functional classes.
Les espaces abstraits et leur utilité en statistique théorique et même en statistique appliquée

© Société de statistique de Paris, 1947, tous droits réservés. L’accès aux archives de la revue « Journal de la société statistique de Paris » (http://publications-sfds.math.cnrs.fr/index.php/J-SFdS) implique l’accord avec les conditions générales d’utilisation (http://www.numdam.org/legal.php). Toute utilisation commerciale ou impression systématique est constitutive d’une infraction pénale. Toute copie ou impression de ce fichier doit contenir la présente mention de copyright.
A concept for building reconstruction from airborne multi-aspect SAR data

In this work we present a new concept towards building reconstruction based on multi-aspect SAR (MASAR) data where we make use of the inherent redundancy and contradiction of MASAR data. Instead of treating every aspect seperately we perform a joint optimization on all available data. For this purpose we use Probabilistic Graphical Model (PGM) as a declarative representation to encode our knowledge and to reconstruct the most likely objects in the scene.
Educating end-stage renal disease patients on dialysis modality selection: clinical advice from the European Renal Best Practice (ERBP) Advisory Board.

Nephrology Clinic, ‘Dr. C. I. Parhon’ University Hospital, Iasi, Romania, Department of Nephrology and Renal Transplantation, University Hospitals, Leuven, Belgium, Nephrology Department, CHU Clemenceau, Caen, France, Department of Clinical Science, Karolinska Institute, Stockholm, Sweden, Renal Division, University Hospital, Ghent, Belgium and Department of Nephrology, ‘E. Herriot’ Hospital, Lyon, France
Autocrine/paracrine TGFβ1 is required for the development of epidermal Langerhans cells

Langerhans cells (LCs) are bone marrow (BM)–derived epidermal dendritic cells (DCs) that develop from precursors found in the dermis. Epidermal LCs are absent in transforming growth factor (TGF) β1-deficient mice. It is not clear whether TGFβ1 acts directly on LC precursors to promote maturation or whether it acts on accessory cells, which in turn affect LC precursors. In addition, the physiologic source of TGFβ1 is uncertain because BM chimera experiments showed that neither hematopoietic nor nonhematopoietic-derived TGFβ1 is required for LC development. To address these issues, we created mice transgenic for a bacterial artificial chromosome (BAC) containing the gene for human Langerin into which Cre recombinase had been inserted by homologous recombination (Langerin-Cre). These mice express Cre selectively in LCs, and they were bred to floxed TGFβRII and TGFβ1 mice, thereby generating mice with LCs that either cannot respond to or generate TGFβ1, respectively. Langerin-Cre TGFβRII mice had substantially reduced numbers of epidermal LCs, demonstrating that TGFβ1 acts directly on LCs in vivo. Interestingly, Langerin-Cre TGFβ1 mice also had very few LCs both in the steady state and after BM transplantation. Thus, TGFβ1 derived from LCs acts directly on LCs through an autocrine/paracrine loop, and it is required for LC development and/or survival.
GFP-Based Fluorescence Assay for CAG Repeat Instability in Cultured Human Cells

Trinucleotide repeats can be highly unstable, mutating far more frequently than point mutations. Repeats typically mutate by addition or loss of units of the repeat. CAG repeat expansions in humans trigger neurological diseases that include myotonic dystrophy, Huntington disease, and several spinocerebellar ataxias. In human cells, diverse mechanisms promote CAG repeat instability, and in mice, the mechanisms of instability are varied and tissue-dependent. Dissection of mechanistic complexity and discovery of potential therapeutics necessitates quantitative and scalable screens for repeat mutation. We describe a GFP-based assay for screening modifiers of CAG repeat instability in human cells. The assay exploits an engineered intronic CAG repeat tract that interferes with expression of an inducible GFP minigene. Like the phenotypes of many trinucleotide repeat disorders, we find that GFP function is impaired by repeat expansion, in a length-dependent manner. The intensity of fluorescence varies inversely with repeat length, allowing estimates of repeat tract changes in live cells. We validate the assay using transcription through the repeat and engineered CAG-specific nucleases, which have previously been reported to induce CAG repeat instability. The assay is relatively fast and should be adaptable to large-scale screens of chemical and shRNA libraries.
Human Attention Modelization and Data Reduction

Attention is so natural and so simple: every human, every animal and even every tiny insect is perfectly able to pay attention. In reality as William James, the father of psychology said: "Everybody knows what attention is". It is precisely because everybody "knows" what attention is that few people tried to analyze it before the 19th century. Even though the study of attention was initially developed in the field of psychology, it quickly spread into new domains such as neuroscience to understand its biological mechanisms and, most recently, computer science to model attention mechanisms. There is no common definition of attention, and one can find variations depending on the domain (psychology, neuroscience, engineering, . . . ) or the approach which is taken into account. But, to remain general, human attention can be defined as the natural capacity to selectively focus on part of the incoming stimuli, discarding less "interesting" signals. The main purpose of the attentional process is to make best use of the parallel processing resources of our brains to identify as quickly as possible those parts of our environment that are key to our survival.
Social media and the McDonaldization of friendship

Abstract This article employs the concept of McDonaldization introduced by George Ritzer (1993) in his Weberian analysis of the processes of formal rationalization characteristic of late modern consumer society to reflect on the social and cultural implications of the most recent wave of communication technologies – social media. It argues that social media smuggle formal rationality into the elementary forms of social interaction, most clearly illustrated through the way they redefine the notion of friendship. In an attempt to lay the ground for a “multiperspectivist approach” (Kellner, 1999) to this phenomenon, the article enters the Weberian argument into a conversation with other styles of theorizing social media such as Marxism, Critical Theory and sociological phenomenology.
Visualizing Mobility of Public Transportation System

Public transportation systems (PTSs) play an important role in modern cities, providing shared/massive transportation services that are essential for the general public. However, due to their increasing complexity, designing effective methods to visualize and explore PTS is highly challenging. Most existing techniques employ network visualization methods and focus on showing the network topology across stops while ignoring various mobility-related factors such as riding time, transfer time, waiting time, and round-the-clock patterns. This work aims to visualize and explore passenger mobility in a PTS with a family of analytical tasks based on inputs from transportation researchers. After exploring different design alternatives, we come up with an integrated solution with three visualization modules: isochrone map view for geographical information, isotime flow map view for effective temporal information comparison and manipulation, and OD-pair journey view for detailed visual analysis of mobility factors along routes between specific origin-destination pairs. The isotime flow map linearizes a flow map into a parallel isoline representation, maximizing the visualization of mobility information along the horizontal time axis while presenting clear and smooth pathways from origin to destinations. Moreover, we devise several interactive visual query methods for users to easily explore the dynamics of PTS mobility over space and time. Lastly, we also construct a PTS mobility model from millions of real passenger trajectories, and evaluate our visualization techniques with assorted case studies with the transportation researchers.
Unstable dynamical systems: Delays, noise and control

Escape from an unstable fixed point in a time-delayed dynamical system in the presence of additive white noise depends on both the magnitude of the time delay, τ, and the initial function. In particular, the longer the delay the smaller the variance and hence the slower the rate of escape. Numerical simulations demonstrate that the distribution of first passage times is bimodal, the longest first passage times are associated with those initial functions that cause the greatest number of delayed zero crossings, i.e. instances where the deviations of the controlled variable from the fixed point at times t and t- τ have opposite signs. These observations support the utility of control strategies using pulsatile stimuli triggered only when variables exceed certain thresholds.
An SDN-based fault-tolerant routing protocol with one wormhole routing technique

A mesh network, which enjoys high connectivity, is very fragile to destroying events. These events will destroy some parts of the network and affect the network performance for a long time. Therefore, devising fault-tolerant routing algorithms for mesh networks is significantly important. In this paper, we introduce a Software-Defined Networking-based (SDN-based) fault-tolerant routing algorithm for a mesh network according to one existing wormhole routing technique because the concepts of SDN-based routing introduced recently and early wormhole routing are similar. Particularly, unlike the latter, we need not to assume that states of all nodes are known in advance. Instead, via the centralized management of the SDN controller, we propose a procedure to find the states of all nodes in flight. Moreover, with the management of OpenFlow flow tables, the implementation complexity of the routing algorithm can be simplified. Finally, we perform some simulation experiments to demonstrate the fault-tolerant capability of our SDN-based routing protocol.
Physicochemical Properties of Nanomaterials: Implication in Associated Toxic Manifestations

Nanotechnology has emerged as one of the leading fields of the science having tremendous application in diverse disciplines. As nanomaterials are increasingly becoming part of everyday consumer products, it is imperative to assess their impact on living organisms and on the environment. Physicochemical characteristics of nanoparticles and engineered nanomaterials including size, shape, chemical composition, physiochemical stability, crystal structure, surface area, surface energy, and surface roughness generally influence the toxic manifestations of these nanomaterials. This compels the research fraternity to evaluate the role of these properties in determining associated toxicity issues. Reckoning with this fact, in this paper, issues pertaining to the physicochemical properties of nanomaterials as it relates to the toxicity of the nanomaterials are discussed.
Tarantism, dancing mania and demonopathy: the anthro-political aspects of ‘mass psychogenic illness’

Synopsis This study questions the widely held assumption that the phenomenon known as mass psychogenic illness (MPI) exists per se in nature as a psychiatric disorder. Most MPI studies are problematical, being descriptive, retrospective investigations of specific incidents which conform to a set of pre-existing symptom criteria that are used to determine the presence of collective psychosomatic illness. Diagnoses are based upon subjective, ambiguous categories that reflect stereotypes of female normality which assume the presence of a transcultural disease or disorder entity, underemphasizing or ignoring the significance of episodes as culturally conditioned roles of social action. Examples of this bias include the mislabelling of dancing manias, tarantism and demonopathy in Europe since the Middle Ages as culture-specific variants of MPI. While ‘victims’ are typified as mentally disturbed females possessing abnormal personality characteristics who are exhibiting cathartic reactions to stress, it is argued that episodes may involve normal, rational people who possess unfamiliar conduct codes, world-views and political agendas that differ significantly from those of Western-trained investigators who often judge these illness behaviours independent of their local context and meanings.
Affect Regulation and Treatment for Depression and Anxiety through Art: Theoretical Ground and Clinical

Advances in neuroscience research have shown that depression and anxiety are closely related to affect regulation, the emotional processes that work within the brain system. This paper reviews two major areas of affect regulation. The first area accounts for the relationships between affect regulation and the functions of the left/right hemispheric brain, as well as the effect of these emotional processes on the autonomic nervous system. The interpersonalneurobiological basis of affect regulation is also elaborated. The discussion implies that depressed and anxious individuals with seriously disturbed emotional or cognitive processes could probably benefit from the enhancement of right hemispheric brain processes via nonverbal form of communication. With capabilities of strengthening emotional and nonverbal processes that occur in the right hemispheric brain, nonverbal forms of psychotherapy, including art therapy, could have benefits in the treatment of depression and anxiety. On the theoretical basis of affect regulation, the second area of discussion focuses on how the assessment and healing functions of various art media adopted in art therapy treatment correlate with left/right hemispheric brain processes. The discussion sheds light on the therapeutic use of art media to allow individuals with mood problems to experience, express, and communicate emotions effectively via nonverbal forms of treatment. The mind-body approach and the various processes of art therapy treatment can attune psycho physiological processes and help to integrate brain processes holistically to improve affect regulation and enhance well-being.
Towards fault-tolerant cryptographic computations over finite fields

Cryptographic schemes, such as authentication, confidentiality, and integrity, rely on computations in very large finite fields, whose hardware realization may require millions of logic gates. In a straightforward design, even a single fault in such a complex circuit is likely to yield an incorrect result and may be exploited by an attacker to break the cryptosystem. In this regard, we consider computing over finite fields in presence of certain faults in multiplier circuits. Our work reported here deals with errors caused by such faults in polynomial basis multipliers over finite fields of characteristic two and presents a scheme to correct single errors. Towards this, pertinent theoretical results are derived, and both bit-parallel and bit-serial fault tolerant multipliers are proposed.
Clustering in Geo-Social Networks

The rapid growth of Geo-Social Networks (GeoSNs) provides a new and rich form of data. Users of GeoSNs can capture their geographic locations and share them with other users via an operation named checkin. Thus, GeoSNs can track the connections (and the time of these connections) of geographic data to their users. In addition, the users are organized in a social network, which can be extended to a heterogeneous network if the connections to places via checkins are also considered. The goal of this paper is to analyze the opportunities in clustering this rich form of data. We first present a model for clustering geographic locations, based on GeoSN data. Then, we discuss how this model can be extended to consider temporal information from checkins. Finally, we study how the accuracy of community detection approaches can be improved by taking into account the checkins of users in a GeoSN.
Joint coding rate control for audio streaming in short range wireless networks

Streaming high quality audio/video (AV) from home media sources to TV sets and audio speakers over a wireless local area network (WLAN) is a challenging problem because of the fluctuating bandwidth caused by interference and fading. Retransmission and data buffering, as common techniques in data transfer over error-prone channels, are not adequate for delay sensitive applications such as high quality audio streaming. Our approach is to adjust the audio data rate dynamically in order to improve the perceptual quality of audio according to wireless channel quality. In this paper we specifically focus on robust audio streaming over short range wireless channels. The major strength of the proposed algorithm is in its ability to match the source and channel coding parameters to the given channel conditions, thus providing better quality and lower latency of audio in home networking.
TEASIng apart alien species risk assessments: a framework for best practices.

Some alien species cause substantial impacts, yet most are innocuous. Given limited resources, forecasting risks from alien species will help prioritise management. Given that risk assessment (RA) approaches vary widely, a synthesis is timely to highlight best practices. We reviewed quantitative and scoring RAs, integrating > 300 publications into arguably the most rigorous quantitative RA framework currently existing, and mapping each study onto our framework, which combines Transport, Establishment, Abundance, Spread and Impact (TEASI). Quantitative models generally measured single risk components (78% of studies), often focusing on Establishment alone (79%). Although dominant in academia, quantitative RAs are underused in policy, and should be made more accessible. Accommodating heterogeneous limited data, combining across risk components, and developing generalised RAs across species, space and time without requiring new models for each species may increase attractiveness for policy applications. Comparatively, scoring approaches covered more risk components (50% examined > 3 components), with Impact being the most common component (87%), and have been widely applied in policy (> 57%), but primarily employed expert opinion. Our framework provides guidance for questions asked, combining scores and other improvements. Our risk framework need not be completely parameterised to be informative, but instead identifies opportunities for improvement in alien species RA.
Consumption of fruits and vegetables among adolescents: a multi-national comparison of eleven countries in the Eastern Mediterranean Region

Abstract Regional cross-country profile of fruit and vegetable (F&V) consumption is lacking in the Eastern Mediterranean Region (EMR). This study examines the prevalence and differences of consuming F&V ≥5 times/d among adolescents in eleven EMR countries, and also describes differences in the proportions of taking F&V ≥5 times/d by sex, age and BMI. The study included 26 328 school adolescents (13–15 years) with complete data on consumption of F&V, age, sex, weight and height taken from the Global School-based Student Health Survey conducted in the EMR between 2005 and 2009. Overall, only 19·4 % of adolescents reported consuming F&V ≥5 times/d. The highest prevalence was reported in Djibouti (40·4 %) and the lowest was reported in Pakistan (10·0 %). Statistically significant differences in prevalence were observed across countries (P<0·05). With the exception of Oman, Libya and Djibouti, significantly more males than females ate F&V ≥5 times/d. Proportion of students consuming F&V ≥5 times/d also varied significantly in all counties based on BMI (P<0·0001), with students within normal BMI having the highest frequency. A negative trend was observed between age and the prevalence of taking F&V ≥5 times/d in most of the eleven EMR countries but Jordan, Djibouti and Morocco. The prevalence of adequate intake of F&V was low in the eleven EMR countries. There is a need for interventions to increase the prevalence of adolescents consuming F&V ≥5 times/d. Interventions should take into consideration psychosocial, environmental and socio-environmental factors influencing F&V intake within countries.