Miracle-dz/UniFAR-FTUs huggingface dataset:
On the developmental origins of human material culture

Material culture – tools, technology, and instrumental skills – has allowed humans to live in almost every habitat on earth. This thesis investigates the developmental roots of human material culture by examining basic tool-use skills and cultural learning abilities in young children. The introduction presents the concepts of the Zone of Latent Solutions (Tennie, Call, & Tomasello, 2009), cumulative culture, and Vygotsky’s (1978) theories as the theoretical background for the following five experiments. Chapter 2 identifies a list of tool-use behaviours that children can invent individually and thus represent an ontogenetic and phylogenetic basis of human tool culture. Chapter 3 extends this list by several behaviours involving the use of two tools in combination (Associative tool use). Chapter 4 focuses on a cultural behaviour that children can only acquire socially. It uses an adapted version of the spaghetti tower task (Caldwell & Millen, 2008a) to study whether children can copy a material cultural product that they could not have invented on their own and whether they can do so without action information. Chapter 5 uses the same task to investigate whether groups of children can produce a ratchet effect. The discussion summarizes the findings and presents limitations and directions for future research.
The requirement for DM in class II-restricted antigen presentation and SDS-stable dimer formation is allele and species dependent

Recently several cell lines have been identified with mutations in a major histocompatibility complex (MHC)-linked protein that lead to defects in class II-restricted antigen presentation and a defect in the formation of class II SDS-stable dimers. The defect in these cells has recently been shown to result from the inability to express the MHC- encoded nonclassical class II molecule called DM. To further examine the role of DM in class II-restricted antigen presentation, we asked if this defect would equally affect different allelic and species variants of class II molecules. To investigate this, we transfected the parent cell lines T1 and 8.1. 6 and their respective antigen presentation mutants T2 and 9.5. 3 with the genes encoding I-Ad and examined the derived transfectants for their ability to present antigen, the conformation of I-Ad at the cell surface, association of I-Ad with invariant chain (Ii), and the ability to form I-Ad SDS-stable dimers. The lack of functional DM expression did not affect any of the anti-I- Ad monoclonal antibody (mAb) epitopes tested or the ability of I-Ad to associate and dissociate with Ii. Surprisingly, these studies also revealed that the antigen presentation defect observed for DR in the 9.5. 3 cells did not compromise I-Ad-restricted antigen presentation. In addition, we found that the level of SDS-stable dimer formation did not correlate with antigen presentation capacity for I-Ad and that the amount of SDS-stable I-Ad dimer depends on the cellular context in which the class II molecule is expressed. Our results suggest that the ability to form SDS-stable dimer is not strictly correlated with class II-restricted antigen presentation. Finally, when two allelic forms of murine class II molecules were compared in the defective T2 cell line, it was found that I-Ak but not I-Ad forms SDS-stable dimers equivalent to that seen in the parental cell lines. Overall, our results suggest that DM may modulate rather than play a requisite role in I-Ad- restricted antigen presentation and SDS-stable dimer formation and that dependency on DM may be allele or species specific.
Agile development cycle: Approach to design an effective Model Based Testing with Behaviour driven automation framework

Model Based Testing (MBT) is a relatively an approach widely discussed in software testing. It extends test automation from test design to test execution using automatic test generation from models. The effective use of this approach requires new skills, technology and knowledge, such as test modelling skills, but also good programs and tool support. This paper explores a design of a Behaviour driven test automation framework using MBT and how it can be effectively used during Agile Development. The automation framework is experimented upon the integration of the Graphwalker, a Model Based Graphical User Interface test generator with behaviour driven development framework and Robot Framework.
Fast Evolution by Multiple Offspring Competition for Genetic Algorithms

The premature convergence of genetic algorithms (GAs) is the most major factor of slow evolution of GAs. In this paper we propose a novel method to solve this problem through competition of multiple offspring of individuals. Unlike existing methods, each parents in our method generates multiple offspring and then generated multiple offspring compete each other, finally winner offspring become to real offspring. From this multiple offspring competition, our GA rarely falls into the premature convergence and easily gets out of the local optimum areas without negative effects. This makes our GA fast evolve to the global optimum. Experimental results with four function optimization problems showed that our method was superior to the original GA and had similar performances to the best ones of queen-bee GA with best parameters.
Differentiation of the Four Major Species of Cinnamons (C. burmannii, C. verum, C. cassia, and C. loureiroi) Using a Flow Injection Mass Spectrometric (FIMS) Fingerprinting Method

A simple and efficient flow injection mass spectrometric (FIMS) method was developed to differentiate cinnamon (Cinnamomum) bark (CB) samples of the four major species (C. burmannii, C. verum, C. aromaticum, and C. loureiroi) of cinnamon. Fifty cinnamon samples collected from China, Vietnam, Indonesia, and Sri Lanka were studied using the developed FIMS fingerprinting method. The FIMS fingerprints of the cinnamon samples were analyzed using principal component analysis (PCA). The FIMS technique required only 1 min of analysis time per sample. The representative samples from each of the four major species of cinnamon were further examined using an ultrahigh-performance liquid chromatography–high-resolution mass spectrometry system, and the chemical differences between the four species were profiled. The results showed that the 1 min FIMS fingerprinting method successfully differentiated the four cinnamon species studied.
Identification of Symptomatic Fetuses Infected with Cytomegalovirus Using Amniotic Fluid Peptide Biomarkers

Cytomegalovirus (CMV) is the most common cause of congenital infection, and is a major cause of sensorineural hearing loss and neurological disabilities. Evaluating the risk for a CMV infected fetus to develop severe clinical symptoms after birth is crucial to provide appropriate guidance to pregnant women who might have to consider termination of pregnancy or experimental prenatal medical therapies. However, establishing the prognosis before birth remains a challenge. This evaluation is currently based upon fetal imaging and fetal biological parameters, but the positive and negative predictive values of these parameters are not optimal, leaving room for the development of new prognostic factors. Here, we compared the amniotic fluid peptidome between asymptomatic fetuses who were born as asymptomatic neonates and symptomatic fetuses who were either terminated in view of severe cerebral lesions or born as severely symptomatic neonates. This comparison allowed us to identify a 34-peptide classifier in a discovery cohort of 13 symptomatic and 13 asymptomatic neonates. This classifier further yielded 89% sensitivity, 75% specificity and an area under the curve of 0.90 to segregate 9 severely symptomatic from 12 asymptomatic neonates in a validation cohort, showing an overall better performance than that of classical fetal laboratory parameters. Pathway analysis of the 34 peptides underlined the role of viral entry in fetuses with severe brain disease as well as the potential importance of both beta-2-microglobulin and adiponectin to protect the injured fetal brain infected with CMV. The results also suggested the mechanistic implication of the T calcium channel alpha-1G (CACNA1G) protein in the development of seizures in severely CMV infected children. These results open a new field for potential therapeutic options. In conclusion, this study demonstrates that amniotic fluid peptidome analysis can effectively predict the severity of congenital CMV infection. This peptidomic classifier may therefore be used in clinical settings during pregnancy to improve prenatal counseling.
Comparison of auto-encoders with different sparsity regularizers

Generally, in order to learn sparse representations for raw inputs via an auto-encoder, the Kullback-Leibler (KL) divergence as a sparsity regularizer is introduced to the loss function for penalizing active code units. In fact, there exist other sparsity regularizers except the KL divergence. This paper introduces some classical sparsity regularizers into auto-encoders, and empirically gives a survey on the auto-encoders with different sparsity regularizers. Specifically, we analyze another two sparsity regularizers which are usually used in sparse coding. In addition, we also consider the effect of different activation functions and different sparsity regularizers on learning performance of auto-encoders. Our experiments are conducted on the datasets of MNIST and COIL.
Design of Active Clamp for Fast Transient Voltage Regulator-Down ( VRD ) Applications

Since the early 80s, the computer industry has undergone great expansion. Processors are becoming faster and more powerful. Power management issues in computing systems are becoming more and more complex and challenging. An evolution began when the high-performance Pentium processor was driven by a non-standard, less-than-5V power supply, instead of drawing its power from the 5V plane on the system board. A so-called Voltage Regulator Module (VRM) is put close to the processor in order to provide the power as quickly as possible. Nowadays, for desktop and workstation applications, VRM input voltage has moved to the 12V output of the silver box. In the meantime, microprocessors will run at very low voltage (below 1V), will consume up to 100A of current, and will have dynamics of about 400A/us. In the near future, VRM will be replaced with VRD because of the parasitic components effect. The specifications requirements for VRD are even more challenging than VRM [1]. iii With this kind of tight tolerance, high current and fast current slew rate, transient response requirements for VRD design are very challenging, especially for step-down transient. During step-down transient, there is some additional energy stored in inductor. Traditional switching regulator like multi-phase buck can do nothing for this even by saturating the duty cycle to 0. All of the additional energy in inductor will be dumped into output cap and cause a large voltage spike at the output voltage. Even for step-up transient, traditional linear control like voltage loop control can't provide enough bandwidth because of the slow compensation and slow slew rate of the error amplifier. So the voltage drop is still quite large. Comparing with traditional linear controlled switching regulator such as voltage control and current control buck converter, active clamp has a lot of the advantages for the transient response. With proper design, active clamp can generate a very high bandwidth since there is no compensator needed in the control loop. Since active clamp bypasses inductor and is connected directly to the output cap, it can quickly source and sink current from the output cap even during the step-down transient and prevent overshooting of the output voltage. This is the biggest advantage for active clamp comparing with traditional linear control. In this thesis, a new active clamp structure is proposed. Several new concepts are proposed like non-linear Gm, built-in offset Gm, error signal feedback and AVP design. A one-channel buck …
Differences in the high speed match-play characteristics of rugby league players before, during and after a period of tramseridian transition

There is a paucity of information comparing competitive rugby league match play dynamics between northern and southern hemispheres. Notably, differences in the match demands of games played in an intensive period have not previously been reported. This study is the first to assess such demands, quantified using GPS/accelerometer technology, during a competitive three game period that comprised two games in England, interspersed with one game in Australia. The three games were completed over a period of 23 days. In-game data from fifteen elite level rugby league players were collected. The focus was to assess differences in activity profiles undertaken in each game. There were significant increases in the total number of high speed sprints, distance covered at high speed and acceleration/deceleration efforts undertaken in Australia when compared to England. No significant differences in other key performance indicators were observed. The current findings demonstrate minimal differences in the activity profiles of game play in elite professional rugby league, with the exception of high-speed activity and acceleration/deceleration efforts. The European team were defeated in their game in Australia, with clearly higher levels of total high speed sprints, acceleration and deceleration efforts being observed in that game when compared with games undertaken in England. Such findings emphasise the continuing use of GPS/accelerometer technologies in determining in-game performance characteristics associated with likely success, though the milieu of factors contributing to success must be considered in entirety.
Attitudes Affecting Online learning Implementation in Higher Education

This study explores attitudes towards and affecting online learning implementation (OLI). In recent years there has been greater acceptance of online learning (OL) by institutional decision-makers, as evidenced by higher levels of institutional involvement; nevertheless, the increase in faculty acceptance lags behind. This gap affects the widespread adoption of OL. This paper proposes that faculty acceptance of OL is influenced by attitudes related to four variables that affect practice change: intellectual reluctance, support, change and cost-benefit. Inherently, these attitudes translate into behaviours that influence the level of resistance toward OLI. Resume Cette etude explore les attitudes envers, et affectant, l’instauration de l’apprentissage en ligne. Ces dernieres annees, il y a eu une plus grande acceptation de l’apprentissage en ligne par les decideurs, comme on peut le voir par l’augmentation de l’implication institutionnelle; cependant, les professeures et professeurs ne suivent pas. Cet ecart affecte l’adoption a grande echelle de l’apprentissage a distance. Cet article propose que l’acceptation par les professeures et professeurs de l’apprentissage a distance est influencee par les attitudes liees a quatre variables qui affectent le changement de pratique : mefiance intellectuelle, soutien, changement et cout-benefice. Ces attitudes se traduisent par des comportements qui influencent le niveau de resistance a l’apprentissage en ligne.
A Fault-Tolerant Distributed Directory Service for Mobile Agents

Two major approaches have been proposed to route messages transparently to mobile agents. Either messages may be sent to a fixed “home agent”, which forwards them to mobile agents, or messages may follow forwarding pointers left by mobile agents. A home agent appears as a single point of failure: when it exhibits a failure, it becomes impossible to track mobile agents or to route messages to them. Similarly, the failure of a node containing a forwarding pointer may prevent the delivery of messages routed through that node; however, the distributed nature of the forwarding pointer approach offers opportunities to introduce redundancy in order to tolerate failures. In the context of a communication layer for mobile agents, we define a directory service as the component that tracks mobile agents’ positions; the information it provides may be used to route messages to mobile agents. We have designed a fault tolerant distributed directory service for mobile agents, which extends the forwarding pointer approach, by introducing redundancy in the information about agents’ locations. The correctness of the algorithm is established by proving two properties. The safety property ensures that the location returned by the directory service is the one occupied by the agent; the liveness property guarantees that location information gets updated as agents migrate. We have formalised the algorithm and derived a fully mechanical proof of its correctness using the proof assistant Coq; the complete source code of the proof is made available from the WWW.
Power Estimation for an Application on the Xscale Platform Using PMU events

In this paper we present a new power estimation model for an application above the operation system. This method uses the performance monitor unit (PMU) events to predicate the power an application consumed. This model maps the hardware events to the power dissipation for the processor and memory when a specific application is running. We use some diffusely selected benchmarks to test our model. The result shows that it is an exact method to the estimation of the power consumption for any application above the OS
La universidad emprendedora como ecosistema de servicio: el caso de Link By UMA-Atech .

espanolLa Universidad para una sociedad emprendedora ha de facilitar entornos favorables para que la comunidad universitaria pueda idear y desarrollar proyectos de emprendimiento. Existe la necesidad de disenar modelos para la Universidad que tengan en cuenta la naturaleza colaborativa de la creacion de valor. El presente trabajo plantea y valida la concepcion de la Universidad emprendedora como un ecosistema de servicio definido por las relaciones de co-creacion entre actores integradores de recursos con capacidad para generar emprendimiento en las universidades. El trabajo analiza la informacion derivada de la ejecucion del modelo Link By UMA-ATechen la Universidad de Malaga EnglishThe University for an Entrepreneurial Society has to facilitate favorable environments for the university community to devise and develop entrepreneurial initiatives. There is a need to design models for the University that take into account the collaborative nature of value creation. The present work raises and validates the conception of the Entrepreneurial University as a service ecosystem defined by the co-creation relations between actors integrating resources with capacity to generate entrepreneurship in the universities. The paper analyzes the information derived from the execution of the Link By UMA-ATech model at the University of Malaga.
The Performance Effect of Multi-core on Scientific Applications

The historical trend of increasing single CPU performancehas given way to roadmap of increasing core count. The challenge ofeffectively utilizing these multi-core chips is just starting to beexplored by vendors and application developers alike. In this study, wepresent some performance measurements of several complete scientificapplications on single and dual core Cray XT3 and XT4 systems with a viewto characterizing the effects of switching to multi-core chips. Weconsider effects within a node by using applications run at lowconcurrencies, and also effects on node-interconnect interaction usinghigher concurrency results. Finally, we construct a simple performancemodel based on the principle on-chip shared resource--memorybandwidth--and use this to predict the performance of the forthcomingquad-core system.
Differential Gene Expression in Vascular Smooth Muscle Cells in Primary Atherosclerosis and In Stent Stenosis in Humans

Objective—We sought to identify differentially expressed genes in human in stent stenosis (ISS) to provide insights into the mechanism of disease. Methods and Results—Using representation difference analysis, we examined differential gene expression between cultured normal human medial vascular smooth muscle cells (VSMCs) and cells from primary atherosclerotic plaques or ISS sites. Specific groups of genes were overexpressed in ISS and plaque VSMCs, including cell cycle regulatory proteins and cell matrix and contractile proteins. Differential expression was validated by virtual Northern analysis, reverse transcriptase-polymerase chain reaction, in situ hybridization, and immunohistochemistry. All ISS genes were expressed by normal intima and had even higher expression in primary plaque VSMCs. Conclusions—ISS VSMCs have a stable gene expression profile reflecting an intimal pattern, intermediate between normal medial and primary plaque VSMCs. Differential expression profiling may identify markers of disease that are overexpressed in ISS and also help elucidate the origin of the ISS lesion.
Securing Vehicular Communications - Assumptions, Requirements, and Principles

Among civilian communication systems, vehicular networks emerge as one of the most convincing and yet most challenging instantiations of the mobile ad hoc networking technology. Towards the deployment of vehicular communication systems, security and privacy are critical factors and significant challenges to be met. Thanks to the substantial research efforts carried out by the community so far, we make the following contributions in this paper: we outline security requirements for vehicular communication systems, we provide models for the system and the communication, as well as models for the adversaries, and propose a set of design principles for future security and privacy solutions for vehicular communication systems.
Web‐Based Corporate, Social and Video Recruitment Media: Effects of Media Richness and Source Credibility on Organizational Attraction

Despite the high use of social media in graduate recruitment campaigns, research has yet to examine how it compares with websites and videos in influencing job seekers' reactions. Drawing from recruitment, media richness, and source credibility theories, we proposed that the media used to present recruitment material would influence organizational attraction via perceptions of media richness and source credibility. Results of a between-subjects study, with 342 participants holding or working toward a degree, show that when a standardized recruitment message is delivered via Facebook, video, or text-based webpage media, there are significant between-media richness and source credibility differences. Furthermore, particular media richness features were positively related to perceptions of source credibility, and source credibility perceptions were positively related to organizational attraction. Implications for organizations' online recruitment campaigns are discussed.
An experimental evaluation of approaches to feature testing in the mobile phone applications domain

Software engineering is a discipline that cannot be applied based solely on elegant theories. Real software production requires software solutions that may apply a mixture of engineering and ad-hoc practices in a systematic way. In this sense, experimentation is staple for identifying the best practices and solutions for a given software development problem. This paper presents results from an experimental evaluation of the use of model-based testing and the use of exploratory testing in the context of feature testing for mobile phone applications. The study is based on the Goal/Question/Metric paradigm. From the results obtained and conclusions reached, an approach to feature testing is proposed.