Miracle-dz/UniFAR-FTUs huggingface dataset:
Analysis of the Realistic Resolution with Angle of Arrival for Indoor Positioning

Increasing importance of localizing objects in indoor environments is the motivation for many research on localization algorithms. This paper focuses on the maximum achievable resolution for Angle of Arrival as a means to position objects inside rooms using equipment within the field of wireless sensor networks, thus dealing with restricted resources. A clear view on beam forming using antenna arrays is represented and is proven to be useful in Angle of Arrival measurements. The choice of the linear antenna array as most appropriate solution is motivated. A detailed overview of the algorithm, used to calculate the maximum realistic resolution, leads us to draw conclusions concerning the resolution. Depending on the number of anchor nodes and the composition of the antenna arrays, a reference value can be defined to calculate the realistic resolution for all room dimensions.
Uncovering Modes of Interorganizational Governance of IT

This research aims to better understand how IT governance supports organizations in their business exchanges with other organizations by investigating further the various modes of interorganizational governance of IT. After conducting case studies and interviews with committee members and IT executives, two modes of governance of IT during interorganizational relationships were uncovered: outsourced mode and networked mode.
Purification and partial characterization of a novel lectin from Dioclea lasiocarpa Mart seeds with vasodilator effects

A lectin from seeds of Dioclea lasiocarpa (DLL) was purified in a single step by affinity chromatography in a Sephadex G‐50 column. DLL haemagglutinated rabbit erythrocytes showing stability even after 1 h of exposure to a different pH values (optimal between pH 6.0 and 8.0) but was inhibited after incubation with d‐mannose and d‐glucose. The pure protein possessed a molecular weight of 25 kDa by sodium dodecyl sulfate polyacrylamide gel electrophoresis and 25,410Da by mass spectrometry. The results analyzed by the software SELCON 3 indicate that β‐sheet secondary structures are predominant in DLL (approximately 40.2% antiparallel β‐sheet, 4.6% parallel β‐sheet, 7.2% α‐helices, 17.3% turns, and 28.7% unordered structures). Mechanical activity of isolated aorta from rat measured by cumulative concentration curves of DLL, performed at the contraction plateau induced by phenylephrine in either endothelium‐intact or denuded aorta. DLL (IC50 = 34.12 ± 3.46 µg/ml) relaxed precontracted endothelized aortic rings by 34.61 ± 9.06%, 55.19 ± 11.9%, and 81.33 ± 14.35%, respectively, at 10 µg/ml (initial concentration), 30 µg/ml, and 100 µg/ml (maximum effect). All effects occurred via interaction with lectin domains and participation of nitric oxide. Copyright © 2012 John Wiley & Sons, Ltd.
Compliance with recommendations for giving vitamin K to newborn infants

Newborn infants have low plasma concentrations of vitamin K and are at risk of haemorrhagic disease if not given supplemental vitamin K.1 n 1992 an association between intramuscular vitamin K and childhood cancer was reported.2 The British Paediatric Association subsequently recommended that oral vitamin K supplements should be given to newborn infants, with repeat doses for breast fed infants.3 However, the chief medical officer has stated that there is no licensed preparation of vitamin K for oral use available in the United Kingdom.4 The policy regarding vitamin K administration at our hospital was recently changed to follow the British Paediatric Association's recommendations. All infants are given a first oral dose of 0.5 mg of vitamin K within the first 24 hours after birth. A second dose of 0.5 …
Giardiavirus-resistant Giardia lamblia lacks a virus receptor on the cell membrane surface

Giardia lamblia virus (GLV) is a small nonenveloped double-stranded RNA virus that infects specifically the parasitic protozoan G. lamblia. Among the many collected strains of G. lamblia, a few turn out to be highly resistant to the virus infection. Two of these strains, Ac and JH, were subjected to electroporation with the RNA from GLV-infected G. lamblia WB strain. Subsequent studies indicated the presence of GLV double-stranded RNA and GLV protein in the electroporated and propagated cells. Virus particles, released by the transfected cells into the culture medium, were capable of infecting the virus-sensitive G. lamblia WB strain. When the WB cells were incubated with GLV at 4 degrees C and treated with the bifunctional cross-linking reagent disuccinimidyl suberate, little GLV protein was detectable inside the cells by immunofluorescent staining. However, patches of fluorescent granules were found on the membrane surface of the cells, suggesting cross-linking of the viruses with a certain membrane component(s). Similar treatment of the resistant strains Ac and JH showed no fluorescence either inside or outside of the cells. Two other closely related parasitic protozoa, Tritrichomonas foetus and Trichomonas vaginalis, cannot be infected by GLV via either viral infection or RNA transfection. The [35S]cysteine-labeled protein profiles in Triton X-114 extracts of G. lamblia WB, Ac, and JH were compared. The profile of the WB strain differs clearly from that of Ac and JH. It remains to be seen, however, whether this difference is related at all to the different susceptibilities to GLV infection.
Long distance, high spatial resolution distributed temperature measurement using a graded index optical fiber at 1550 nm

Raman-based distributed temperature sensing (DTS) systems have found widely ranging commercial applications. For extended distance DTS measurement the spatial resolution is sometimes limited through pulse broadening caused by the intermodal dispersion of graded index multimode (GIMM) optical fiber. In this paper we describe the design, manufacturing and performance of a high bandwidth GIMM fiber, with bandwidth optimized at 1550 nm. Using this fiber, we demonstrate distributed temperature measurement with an extended distance of 32 km and spatial resolution of 3 meters. In comparison, the spatial resolution of an OM4 (bandwidth optimized for use at 850 nm) fiber typically used in temperature sensing over 32km is more than 10 meters.
Tacit knowledge management: the role of artifacts

This article discusses both the management of tacit knowledge and the tacit approach to knowledge management. Tacit knowledge must be made manageable by being explicated and separated from the knowledge workers, so that the knowledge resources do not go home at night. However, the less knowledge leaving in the evening, the less knowledge will return the following morning. Making the organization as independent as possible of the tacit knowledge of its knowledge workers is an ironic program for knowledge management, since it advocates a reduction of the total resource pool for the sake of managerial control. The article searches for alternatives to knowledge management exercised from a position of control and ownership. A case study of product development is analyzed. This specialized context focuses attention on knowledge mobilization rather than knowledge control and sharing. The artifact provides sufficient pressure for order and coordination to emerge spontaneously. Knowledge management can in such circumstances become tacit without losing its value.
Classification of the Female Hairline and Refined Hairline Correction Techniques for Asian Women

BACKGROUND Hair transplantation has been a highly effective technique in reducing wide foreheads and recontouring the hairline. OBJECTIVE To classify hairline contour in Asian women and to find a way to make an ideal and refined female hairline. MATERIALS & METHODS The hairline contours of 234 female volunteers were classified into five groups. We measured the height and width of foreheads and maximal depth of the infratemporal portion. We also performed hairline correction on 350 female patients with a wide forehead with an M‐shaped hairline. RESULTS Hairlines of the volunteers were grouped as round (27.35%), M‐shaped (28.20%), rectangular (27.35%), bell‐shaped (10.25%), or triangular (2.99%). The average height of the forehead was 6.38±0.89 cm, average width of the forehead 14.30±1.75 cm, and maximal depth of the infratemporal portion 4.29±0.77 cm. In 350 patients operated on, the average area of the frontotemporal recess was 30.1 cm2, and approximately 1,054 follicular units (FU) were needed. CONCLUSION The classification of Asian female hairlines and our refined techniques will be beneficial for correcting wide foreheads with M‐shaped or rectangular hairline contours. The authors have indicated no significant interest with commercial supporters.
Analysis of Distributed Data Base Processing Strategies

In this paper we report on query processing experiments that were performed in one distributed data base environment. In this environment we compared the strategy produced by a collection of algorithms on the basis of number of bytes moved. Among other conclusions we found that limited search algorithms do not perform very well compared to algorithms which exhaust all possible processing plans.
Midlife Healthy-Diet Index and Late-Life Dementia and Alzheimer's Disease

Aim: To study long-term effects of dietary patterns on dementia and Alzheimer’s disease (AD). Methods: Of 525 subjects randomly selected from population-based cohorts surveyed at midlife, a total of 385 (73%) subjects were re-examined 14 years later in the CAIDE study. A healthy-diet index (range 0–17) was constructed including both healthy and unhealthy dietary components. Results: Persons with a healthy diet (healthy-diet index >8 points) had a decreased risk of dementia (OR 0.12, 95% CI 0.02–0.85) and AD (OR 0.08, 95% CI 0.01–0.89) compared with persons with an unhealthy diet (0–8 points), adjusting for several possible confounders. Conclusions: Healthy diet at midlife is associated with a decreased risk of dementia/AD in late life. These findings highlight the importance of dietary patterns and may make more effective measures for dementia/AD prevention or postponement possible.
Belief-directed sequential probabilistic data association multiuser detector

We propose in this paper a novel soft-input-soft-output (SISO) multiuser detector for synchronous CDMA systems. The detector is called the belief-directed sequential probabilistic data association detector (BD-SPDAD). The BD-SPDAD is developed based on a general framework of the probabilistic data association detector (PDAD) proposed in (Y Huang et al, IEEE Int. Symp. on Inf. Theo., 2004). However, novel extensions to the general framework are proposed for the BD-SPDAD, which result in a low complexity sequential implementation. Specifically, the complexity of the BD-SPDAD is reduced from O(K/sup 3/) of the original PDAD to O(K/sup 2/), where K is the number of users in the system. Moreover, we show through simulation that the performance of the BD-SPDAD is comparable and even better than the original PDAD especially in high signal-to-noise regions.
Th-17, monokines, collagen type V, and primary graft dysfunction in lung transplantation.

RATIONALE The pathogenesis of primary graft dysfunction (PGD), a serious complication of lung transplantation, is poorly understood. Human studies and rodent models have shown that collagen type V (col[V]), stimulates IL-17-dependent cellular immunity after lung transplantation. OBJECTIVES To determine whether patients with end-stage lung disease develop pretransplant col(V)-specific cellular immunity, and if so, the impact of this response on PGD. METHODS Trans-vivo delayed-type hypersensitivity (TV-DTH) assays were used to evaluate memory T-cell responses to col(V) in 55 patients awaiting lung transplantation. Pa(O(2))/Fi(O(2)) index data were used to assess PGD. Univariate risk factor analysis was performed to identify variables associated with PGD. Rats immunized with col(V) or irrelevant antigen underwent lung isografting to determine if prior anti-col(V) immunity triggers PGD in the absence of alloreactivity. MEASUREMENTS AND MAIN RESULTS We found that 58.8% (10/17) of patients with idiopathic pulmonary fibrosis, and 15.8% (6/38) of patients without idiopathic pulmonary fibrosis tested while on the wait list for a lung transplant were col(V) DTH positive. Col(V) reactivity was CD4(+) T-cell and monocyte mediated, and dependent on IL-17, IL-1beta, and tumor necrosis factor (TNF)-alpha. Pa(O(2))/Fi(O(2)) indices were impaired significantly 6-72 hours after transplantation in col(V)-reactive versus nonreactive patients. Univariate risk factor analysis identified only preoperative TV-DTH to col(V) and ischemic time as predictors of PGD. Finally, in a rat lung isograft model, col(V) sensitization resulted in significantly lower Pa(O(2))/Fi(O(2)), increased local TNF-alpha and IL-1beta production, and a moderate-to-severe bronchiolitis/vasculitis when compared with control isografts. CONCLUSIONS The data suggest that activation of innate immunity by col(V)-specific Th-17 memory cells represents a novel pathway to PGD after lung transplantation.
Phase transformation behaviour of hydroxyapatite foams subject to heat treatment

This study examined the relationship between sintering and phase transformation behaviour in hydroxyapatite (HA). Pellets and replicated foams were sintered at five different temperatures ranging from 1350 °C to 1550 °C. Hydroxyapatite remained as the major phase in all the samples studied. In the pellets, sintering took place prior to the phase transformation which occurs primarily at the surface. This created damage that extended into the interior of the pellet above 1400 °C. In contrast, the foams transformed at lower temperatures due to the higher surface area. This did not create damage in the foam. The differences in the foams and the pellets are discussed in terms of sintering and phase transformation behaviour.
Performance Evaluation of IP Based Multimedia Services in UMTS

This paper presents our work in the performance evaluation of UMTS network based on simulation. Enhanced UMTS Radio Access Network Extensions for NS-2 (EURANE) developed by SEACORN has brought us to the higher phase of UMTS simulation in third generation wireless telecommunication system. Wireless 3G is designed to be able to deliver various kind of multimedia package through an IP network for the purpose of easier interconnection with fixed network with various existing multimedia services. Multimedia services with their bandwidth consumption characteristics are able to be sent through a UMTS network with the existence of High Speed Data Packet Access (HSPDA) in Release 5. Quality of Service (QoS) is a major concern in multimedia services. This paper shows the performance analysis of a number of multimedia services and their QoS using HSDPA in UMTS. The experiments were based on EURANE extension for NS-2. From the simulation conducted, we found that Unacknowledged Mode (UM) in Radio Link Control (RLC) will perform better for QoS class number 1 (VoIP) and 2 (Video Streaming), while Acknowledged Mode (AM) mode are more suitable for QoS class number 3 (web server) and 4 (FTP).
Being a parent on dialysis: a literature review.

AIM This literature review explored the extant literature to further our understanding of the experience of being a parent on dialysis. METHODS Keywords used to search the literature were haemodialysis, hemodialysis, chronic kidney disease, end stage renal disease, parent and experience. Databases searched included CINAHL, Medline, Wiley/Blackwell, EBSCOHost, Web of Science, Pubmed and ProQuest. Years included were 1999-2009. Seventeen primary research articles (sixteen qualitative, one mixed methods) met the search criteria with only one on parents undergoing dialysis. FINDINGS The experience of the parent on dialysis has rarely been explored in the literature. Related research has indicated important themes including: restricted lives; relationships; adjustment; consequences and future outlook. CONCLUSIONS More should be known about challenges that face parents who receive dialysis. This review established an urgent need for further research to determine the experiences and needs of this population to provide empirical, person-centred nursing care.
Genes and oral cancer

Oral cancers have been one of the leading causes of deaths particularly in the developing countries. Prime reason for this high mortality and morbidity is attributed to the delay in diagnosis and prompt treatment. Relentless research in the field of oncology has led to the advent of novel procedures for the early detection of oral cancers. Molecular biology is highly promising in this regard. It is a procedure that detects alterations at a molecular level much before they are seen under a microscope and much before clinical changes occur. Molecular studies serve as the basis by which we will eventually be able not only to augment clinical assessment and classification of oral lesions but also predict malignant potential of oral lesions, thus reducing the incidence and increasing the scope for early diagnosis and treatment of oral cancers. However, making such sophisticated tools available for the common man in developing countries is one of the most important challenges faced today.
Wearable medical device improves survival for glioblastoma patients

3433 CANCER SEPTEMBER 15, 2017 3 Content in this section does not reflect any official policy or medical opinion of the American Cancer Society or of the publisher unless otherwise noted. © American Cancer Society, 2017. I a recent study conducted by the Wellcome Trust Sanger Institute in Hinxton, United Kingdom, collaborators discovered that a number of breast cancers are genetically similar to rarer cases with faulty BRCA1 or BRCA2 genes.1 As a result, they estimate that up to 20% of breast cancer patients may be able to be treated with poly(adenosine diphosphateribose) polymerase (PARP) inhibitors, which previously were thought to be effective for women with inherited BRCA1 or BRCA2 mutations only. Between 1% and 5% of breast cancer cases are caused by inherited mutations in BRCA1 and BRCA2 genes, which are linked to higher risks of both breast and ovarian cancers. PARP inhibitors are designed to treat tumors with these faulty genes and are also being investigated for use against prostate cancer. In the study, researchers analyzed the breast cancer genomes of 560 patients and examined every possible mutation. They then developed a computer-based tool called HRDetect to identify patterns of mutations in the tumors that were similar to mutations in the BRCA1 and BRCA2 genes. The researchers found that many breast cancer patients had mutational signatures that were identical to those of people with faulty BRCA1 and BRCA2 genes, even though they had not inherited the mutations. The authors say the findings suggest that approximately 1 in 5 breast cancer patients could benefit from existing PARP inhibitor treatment, although clinical trials would be needed to verify that hypothesis. Researchers add that uncovering previous defects in patients’ DNA repair machinery was possible only with the sequencing of the entire genome of the cancers, and additional work is needed to determine whether there are tumors with the same mutational signatures elsewhere in the body that may respond to the drugs.
First Insights into the Entry Process of Hyperthermophilic Archaeal Viruses

ABSTRACT A decisive step in a virus infection cycle is the recognition of a specific receptor present on the host cell surface, subsequently leading to the delivery of the viral genome into the cell interior. Until now, the early stages of infection have not been thoroughly investigated for any virus infecting hyperthermophilic archaea. Here, we present the first study focusing on the primary interactions between the archaeal rod-shaped virus Sulfolobus islandicus rod-shaped virus 2 (SIRV2) (family Rudiviridae) and its hyperthermoacidophilic host, S. islandicus. We show that SIRV2 adsorption is very rapid, with the majority of virions being irreversibly bound to the host cell within 1 min. We utilized transmission electron microscopy and whole-cell electron cryotomography to demonstrate that SIRV2 virions specifically recognize the tips of pilus-like filaments, which are highly abundant on the host cell surface. Following the initial binding, the viral particles are found attached to the sides of the filaments, suggesting a movement along these appendages toward the cell surface. Finally, we also show that SIRV2 establishes superinfection exclusion, a phenomenon not previously described for archaeal viruses.
A multiple alignment program for protein sequences

A program for the multiple alignment of protein sequences is presented. The program is an extension of the fast alignment program by Wilbur et al. (1984) into higher dimensions. The use of hash procedures on fragments of the protein sequences increases the speed of calculation. Thereby we also take into account fragments which are present in some, but not in all, sequences considered. The results of some multiple alignments are given.
Reconfiguration Framework for Multi-kernel Embedded Applications

High utilization of hardware is required in order to conserve space and power as well as to incorporate dynamic adaptability in embedded systems. The space requirements can be greatly reduced through system adaptation by reconfiguring the same hardware to facilitate various customized kernels as execution proceeds. Fortunately the encountered reconfiguration overhead is deterministic. Consequently, if the execution of kernels is carefully scheduled considering also the reconfiguration overhead, a performance gain can be obtained. We present our policy, experiments, and performance results of customizing and reconfiguring actual hardware for embedded kernels implemented on Field-Programmable Gate Arrays (FPGAs). Various synthesized-dynamic and real-static applications containing EEMBC (EDN Embedded Microprocessor Benchmarking Consortium) and MiBench embedded benchmark kernels show substantial performance improvement compared to FIFO heuristics, without ignoring reconfiguration overheads. The proposed policy reduces the required reconfigurations by more than 50%, and performs within 25% of the ideal execution time while conserving 60% of the FPGA resources.
Generalised coinduction

We introduce the $\lambda-coiteration$ schema for a distributive law $\lambda$ of a functor $\Functor{T}$ over a functor $\Functor{F}$. Parameterised by $\Functor{T}$ and $\lambda$ it generalises the basic coiteration schema uniquely characterising functions into a final $\Functor{F}$-coalgebra. Furthermore, the same parameters are used to generalise the categorical notion of a bisimulation to that of a $\lambda-bisimulation$, while still giving rise to a proof technique for bisimilarity. We first present a theorem showing the validity of the resulting definition and proof principles for categories with countable coproducts. Our approach gives a unifying categorical presentation and justification of several extensions of the basic coinduction schemata that have been treated separately before, and some only for specific types of system. As examples, the duals of primitive recursion and course-of-value iteration, which are known extensions of coiteration, arise as instances of our framework. Moreover, we derive schemata involving auxiliary operators definable with GSOS-style specifications such as addition of streams, regular operators on languages, or parallel and sequential composition of processes. The argument is based on a variation of the theory in the setting of monads and copointed functors. The schemata justify guarded recursive definitions and an up-to-context proof technique for operators of the type mentioned. The latter can ease bisimilarity proofs considerably.