Miracle-dz/UniFAR-FTUs huggingface dataset:
Nebular Emission Line Ratios in z ≃ 2–3 Star-forming Galaxies with KBSS-MOSFIRE: Exploring the Impact of Ionization, Excitation, and Nitrogen-to-Oxygen Ratio

We present a detailed study of the rest-optical (3600–7000 Å) nebular spectra of ∼380 star-forming galaxies at , obtained with Keck/Multi-object Spectrometer for Infrared Exploration (MOSFIRE) as part of the Keck Baryonic Structure Survey (KBSS). The KBSS-MOSFIRE sample is representative of star-forming galaxies at these redshifts, with stellar masses and star formation rates SFR = 3–1000 yr−1. We focus on robust measurements of many strong diagnostic emission lines for individual galaxies: [O ii]λλ3727, 3729, [Ne iii]λ3869, Hβ, [O iii] 4960, 5008, [N ii]λλ 6549, 6585, Hα, and [S ii]λλ6718, 6732. Comparisons with observations of typical local galaxies from the Sloan Digital Sky Survey and between subsamples of KBSS-MOSFIRE show that high-redshift galaxies exhibit a number of significant differences in addition to the well-known offset in log([O iii] /Hβ) and log([N ii] /Hα). We argue that the primary difference between H ii regions in galaxies and those at is an enhancement in the degree of nebular excitation, as measured by [O iii]/Hβ and [([O iii] +[O ii] )/Hβ]. At the same time, KBSS-MOSFIRE galaxies are ∼10 times more massive than galaxies with similar ionizing spectra and have higher N/O (likely accompanied by higher O/H) at fixed excitation. These results indicate the presence of harder ionizing radiation fields at fixed N/O and O/H relative to typical galaxies, consistent with Fe-poor stellar population models that include massive binaries, and highlight a population of massive, high-specific star formation rate galaxies at high redshift with systematically different star formation histories than galaxies of similar stellar mass today.
Gesture control system for mobile robots

Current robotics advances offer consequent potential for assistance, not only for individuals, but also for professionals operating on the ground, such as firemen or military. However, such operators must stay focused on their mission; hence they expect a non-invasive, intuitive control system, disrupting them as least as possible. Furthermore, the inherent mobility arising from such missions (walking, running, jumping) must not be an obstacle to gesture recognition. Here, we present a glove-based gesture detection algorithm, whose learning phase is instantaneous among a large span of possible gestures. It has been evaluated on a seven-word dictionary dedicated for the purpose of robot control, with satisfying recognition results.
Effect of dominant follicle persistence on follicular fluid oestradiol and inhibin and on oocyte maturation in heifers.

The aim of the present study was to characterize in detail the cytoplasmic and nuclear morphology of cattle oocytes recovered from follicles that are dominant for more than 9 days (with low fertility after ovulation), and to relate morphological changes to intrafollicular markers of follicle health. Beef heifers received prostaglandin F2 alpha and a synthetic progestagen (3 mg Norgestomet) for 2 or 10 days on the first day of dominance of the second dominant follicle (DF2) of the oestrous cycle, to give a 4 day (n = 19; N2) or 12 day (n = 21; N10) duration of dominance of the dominant follicle at ovariectomy 18 h after implant removal and before the predicted gonadotrophin surge. Ultrasound scanning determined emergence of a new wave of follicles in five N10 heifers the day before (n = 1) or day of ovariectomy (n = 4) (N10-NonDom). Dominant follicles from the remaining N10 heifers (N10-Dom) were larger (P < 0.05) on the day of ovariectomy (17.8 +/- 0.6 mm) than those from N2 heifers (13.6 +/- 0.4 mm). The oestradiol:progesterone ratio of follicular fluid from N10-Dom heifers was reduced (21.7 +/- 3.1 versus 34.1 +/- 4.4; P < 0.05), while inhibin A (as measured by immunoradiometric assay) was increased (12.7 +/- 1.0 versus 9.0 +/- 0.7 micrograms ml-1; P < 0.05) compared with N2 heifers. Eleven of twelve N2 oocytes demonstrated nuclear activation without germinal vesicle breakdown, while seven of eight N10-Dom oocytes had undergone germinal vesicle breakdown and had progressed to metaphase I (6/8) or II (1/8). In contrast to N2 oocytes, N10-Dom oocytes showed a larger perivitelline space containing more cumulus cell process endings, vacuoles, irregular vesicles, and more mitochrondia and lipid droplets throughout the ooplasm, yet the degree of cumulus cell expansion and atresia was similar. Thus, final oocyte maturation leading to metaphase I is initiated in most dominant follicles with a dominance period of > 9 days before the gonadotrophin surge and is associated with a reduction in dominant follicle health. However, ovulatory ability is maintained and will lead to the ovulation of aged oocytes, markedly reducing subsequent pregnancy rates.
Cyberhate

American extremists have traditionally cultivated technology to enhance efficiency and promote goals. This article concentrates on how domestic right-wing and other extremists have used computer networks to these ends. Although the concept of a guerrilla insurgency through “leaderless resistance” became a factor in right-wing extremist movements before the Internet's advent, cyberspace hastened its popularity. The Internet has been useful to hatemongers and extremists because it is economical and far reaching, and online expression is significantly protected by the First Amendment. Various court decisions have established that not all communication is protected, in cyberspace or elsewhere. Although the government cannot regulate Internet expression because it offends sensibilities, it can regulate expression that constitutes crimes that fall under various unprotected areas of speech. Courts have convicted hatemongers who use the Internet to communicate threats rather than merely ideas. Private service providers and foreign governments have greater latitude to prohibit offensive and hateful expression that does not constitute a threat.
ETH-Tight Algorithm for Cycle Packing on Unit Disk Graphs

In this paper, we consider the Cycle Packing problem on unit disk graphs defined as follows. Given a unit disk graph G with n vertices and an integer k, the goal is to find a set of $k$ vertex-disjoint cycles of G if it exists. Our algorithm runs in time $2^{O(\sqrt k)}n^{O(1)}$. This improves the $2^{O(\sqrt k\log k)}n^{O(1)}$-time algorithm by Fomin et al. [SODA 2012, ICALP 2017]. Moreover, our algorithm is optimal assuming the exponential-time hypothesis.
Pleasant Events-Based Behavioral Intervention for Depression in Nursing Home Residents

ABSTRACT In this theoretical/review article, we set forth a conceptual model and empirical evidence as the foundation for a behavioral intervention in nursing homes involving pleasant events. The risk for depression is nearly twice as great among nursing home residents as it is for community-residing elders, with up to 50% of nursing home residents affected by significant depressive symptoms. Although we now have a good understanding of the epidemiology and manifestations of depression in late life, and are beginning to apply effective treatments to some groups of elders, the benefits of the past decade of research have yet to reach the frailest elders living in nursing homes. The health and cognitive multiple comorbidity of this population makes treatment extremely challenging. The behavioral model we describe is based on the work of Lewinsohn and others. The intervention would adapt work already completed by Teri and her colleagues with elderly dementia patients and their families. We make specific recommendations concerning adapting this treatment approach to nursing homes, and evaluating its effects.
Gender Differences in the Risk of Ischemic Stroke Associated With Aortic Atheromas

Background and Purpose Atherosclerotic plaque of the proximal portion of the aorta is associated with an increased risk of ischemic stroke in the elderly. Different cutoffs of plaque thickness have been used in the literature for risk stratification and have been applied to both men and women. However, the assumption that the relationship between plaque thickness and stroke risk is the same in the 2 genders has not been proven. The aim of this study was to evaluate whether the prevalence of different degrees of aortic plaque thickness differed in men and women with ischemic stroke. Methods We performed transesophageal echocardiography in 152 patients aged >59 years with acute ischemic stroke (76 men and 76 women) and in 152 control subjects of similar age (70 men and 82 women). Odds ratios (ORs) for ischemic stroke with 95% CIs for different plaque thickness definitions were calculated for the overall group and separately for men and women by logistic regression analysis after adjusting for age, arterial hypertension, and hypercholesterolemia. Results Aortic plaques ≥4 mm were significantly more frequent in men than in women (31.5% versus 20.3%, respectively;P =0.025) and were associated with ischemic stroke in both men (adjusted OR 6.0, CI 2.1 to 16.8) and women (adjusted OR 3.2, CI 1.2 to 8.8). However, plaques 3 to 3.9 mm in thickness had a significant association with stroke in women (adjusted OR 4.8, CI 1.7 to 15.0) but not in men (adjusted OR 0.8, CI 0.2 to 3.0). Plaques <3 mm were not associated with a significantly increased stroke risk for either sex. Conclusions Smaller aortic plaques are significantly associated with ischemic stroke in women but not in men. If the increased prevalence of smaller plaques in women is confirmed to be associated with increased risk for embolic stroke, different cutoff points may have to be adopted in men and women for risk stratification and for decisions regarding medical intervention.
Recognition of DNA by Three Ferric Uptake Regulator (Fur) Homologs in Bacillus subtilis

ABSTRACT Bacillus subtilis contains three Fur homologs: Fur, PerR, and Zur. Despite significant sequence similarities, they respond to different stimuli and regulate different sets of genes. DNA target site comparisons indicate that all three paralogs recognize operators with a core 7-1-7 inverted repeat. The corresponding consensus sequences are identical at five or more of the seven defined positions. Using site-directed mutagenesis, the Per box at the mrgA promoter was altered to mimic the core 7-1-7 motif of the Fur and Zur boxes. In vitro, the mrgA promoter containing a Zur box was only recognized by Zur, as demonstrated by DNase I footprinting assays. In contrast, both Fur and PerR bound to the mrgA promoter region containing a consensus Fur box. Expression analysis of these promoters is consistent with the in vitro data demonstrating as few as 1 or 2 base changes per half-site are sufficient to alter regulation. Similarly, the Fur box at the feuA promoter can be converted into a Per or a Zur box by appropriate mutations. While both Fur and PerR could recognize some of the same synthetic operator sequences, no naturally occurring sites are known that are subject to dual regulation. However, the PerR-regulated zosA gene is controlled from a regulatory region that contains both Per and Fur boxes. Although purified Fur protein bound to the candidate Fur boxes, Fur has little effect on zosA expression—possibly due to the location of the Fur boxes relative to the zosA promoter. Together, our results identify two nucleotide positions that are important for the ability of PerR, Fur, and Zur to distinguish among the many closely related operator sites present in the B. subtilis genome.
Why Singapore Trumps Iceland

The article explores how a National Institute of Health policy of racialization-as-inclusion in research informs the building of Asian DNA databases at Biopolis, an emerging biomedical hub in Singapore. Citing variability in DNA and populations in the Asian region, Singaporean biostatisticians challenge DeCode Genetics of Iceland as an exemplary model of genomic research. They claim that genetic traits among populations in Asia that are relatively new to medical genomics – and being gathered ‘in the wild’ – gain value from being calculated and databased. The infrastructure deploys the ethnic heuristic in different registers. First, the network of ethnicity becomes a supple membrane coextensive with the network of genetic data points. Second, ethnicity is rendered an immutable mobile that circulates databases beyond tiny Singapore, making the infrastructure at once situated, flexible, and expansive. Third, the ethnic signifier carries affective value that enhances a sense of what is at stake in the building, mobilization and implications of such Asian databases. In short, the origami-like folding together of multiple, flowable, and perfomative data points shapes a unilateral topological space of biomedical ‘Asia. ’
Can Public Health Risk Assessment Using Risk Matrices Be Misleading?

The risk assessment matrix is a widely accepted, semi-quantitative tool for assessing risks, and setting priorities in risk management. Although the method can be useful to promote discussion to distinguish high risks from low risks, a published critique described a problem when the frequency and severity of risks are negatively correlated. A theoretical analysis showed that risk predictions could be misleading. We evaluated a practical public health example because it provided experiential risk data that allowed us to assess the practical implications of the published concern that risk matrices would make predictions that are worse than random. We explored this predicted problem by constructing a risk assessment matrix using a public health risk scenario—Tainted blood transfusion infection risk—That provides negative correlation between harm frequency and severity. We estimated the risk from the experiential data and compared these estimates with those provided by the risk assessment matrix. Although we validated the theoretical concern, for these authentic experiential data, the practical scope of the problem was limited. The risk matrix has been widely used in risk assessment. This method should not be abandoned wholesale, but users must address the source of the problem, apply the risk matrix with a full understanding of this problem and use matrix predictions to inform, but not drive decision-making.
Lossy compression of noisy remote sensing images with prediction of optimal operation point existence and parameters

Abstract. We address lossy compression of noisy remote sensing images, where the noise is supposed to be spatially uncorrelated (white), additive originally or after a proper variance-stabilizing transformation (VST). In such situations, the so-called optimal operation point (OOP) might exist. The OOP is associated with the parameter that controls compression (e.g., quantization step) for which the compressed image is the closest to the noise-free image according to a certain criterion and is closer than the original noisy image. Lossy compression in the neighborhood of OOP, if it exists, relates to an essential noise filtering effect and some distortions. Then such lossy compression (in the neighborhood of OOP) becomes expedient. However, it may be that OOP does not exist for a given image and the observed noise intensity. In such a situation, it can be reasonable to carry out a more “careful” image compression (with a lower compression ratio). Also, it is expedient to predict the existence of OOP and the compression parameters at this point in advance in order to perform adaptive and automated compression. The OOP existence that can be predicted for some coders based on the discrete cosine transform (DCT) is shown. The proposed prediction procedure is simple and fast. It presumes the calculation of DCT coefficient statistics in nonoverlapping 8×8 pixel blocks for a given image and uses an approximating curve obtained in advance. It is shown that it is possible to predict values for both conventional metrics, such as mean square error or peak-signal-to-noise ratio, and some visual quality metrics for the coder parameters that correspond to a possible OOP. The designed prediction procedure is tested on Hyperion and AVIRIS hyperspectral remote sensing data.
Flavor and antioxidant capacity of peanut paste and peanut butter supplemented with peanut skins.

UNLABELLED Peanut skins (PS) are a good source of phenolic compounds. This study evaluated antioxidant properties and flavor of peanut paste and peanut butter enhanced with peanut skins. PS were added to both materials in concentrations of 0.0%, 0.5%, 1.0%, 5.0%, 10.0%, 15.0%, and 20.0% (w/w). PS, peanut paste, and peanut butter used in the study had initial total phenolics contents of 158, 12.9, and 14.1 mg GAE/g, respectively. Hydrophilic oxygen radical absorbance capacity (H-ORAC) of peanut skins was 189453 μMol Trolox/100 g and addition of 5% PS increased H-ORAC of peanut paste and peanut butter by 52% to 63%. Descriptive sensory analysis indicated that the addition of 1% PS did not change intensity of descriptors in the sensory profile of either peanut paste or peanut butter. Addition of 5% PS resulted in significant differences in woody, hulls, skins; bitter; and astringent descriptors and 10% PS addition resulted in significant differences in most attributes toward more negative flavor. PRACTICAL APPLICATION Peanut skins are a low-value residue material from peanut processing which contain naturally occurring phenolic compounds. The use of this material to improve antioxidant capacity and shelf-life of foods can add value to the material and improve the nutritional value of foods. The improved nutritional qualities and unchanged flavor profile occurring with low levels of peanuts skins in peanut paste and peanut butter suggest potential application of this technology in various food industries.
Antineuropathic and Antinociceptive Drugs Combination in Patients with Chronic Low Back Pain: A Systematic Review

Purpose. Chronic low back pain (LBP) is often characterized by both nociceptive and neuropathic components. While various monotherapies have been reported of only limited efficacy, combining drugs with different mechanisms of action and targets appears a rational approach. Aim of this systematic review is to assess the efficacy and safety of different combined pharmacological treatments, compared to monotherapy or placebo, for the pharmacological treatment of chronic LBP. Methods. Published papers, written or abstracted in English from 1990 through 2011, comparing combined pharmacological treatments of chronic LBP to monotherapy or placebo were reviewed. Results. Six articles met the inclusion criteria. Pregabalin combined with celecoxib or opioids was shown to be more effective than either monotherapy. Oxycodone-paracetamol versus previous treatments and tramadol-paracetamol versus placebo were also reported as effective, while morphine-nortriptyline did not show any benefit over any single agent. Conclusions. In spite of theoretical advantages of combined pharmacological treatments of chronic LBP, clinical studies are remarkably few. Available data show that combined therapy, including antinociceptive and antineuropathic agents is more effective than monotherapy, with similar side effects.
The guanine exchange factor Gartenzwerg and the small GTPase Arl1 function in the same pathway with Arfaptin during synapse growth

ABSTRACT The generation of neuronal morphology requires transport vesicles originating from the Golgi apparatus (GA) to deliver specialized components to the axon and dendrites. Drosophila Arfaptin is a membrane-binding protein localized to the GA that is required for the growth of the presynaptic nerve terminal. Here we provide biochemical, cellular and genetic evidence that the small GTPase Arl1 and the guanine-nucleotide exchange factor (GEF) Gartenzwerg are required for Arfaptin function at the Golgi during synapse growth. Our data define a new signaling pathway composed of Arfaptin, Arl1, and Garz, required for the generation of normal synapse morphology.
Functional Analysis of a Mouse Brain Elk-Type K+Channel

Members of the Ether à go-go (Eag) K+channel subfamilies Eag, Erg, and Elk are widely expressed in the nervous system, but their neural functions in vivoremain largely unknown. The biophysical properties of channels from the Eag and Erg subfamilies have been described, and based on their characteristic features and expression patterns, Erg channels have been associated with native currents in the heart. Little is known about the properties of channels from the Elk subfamily. We have identified a mouse gene, Melk2, that encodes a predicted polypeptide with 48% amino acid identity to Drosophila Elk but only 40 and 36% identity with mouse Erg (Merg) and Eag (Meag), respectively. Melk2 RNA appears to be expressed at high levels only in brain tissue. Functional expression ofMelk2 in Xenopus oocytes reveals large, transient peaks of current at the onset of depolarization. Like Meag currents, Melk2 currents activate relatively quickly, but they lack the nonsuperimposable Cole–Moore shift characteristic of the Eag subfamily. Melk2 currents are insensitive to E-4031, a class III antiarrhythmic compound that blocks the Human Ether-à-go-go-Related Gene (HERG) channel and its counterpart in native tissues, IKr. Melk2 channels exhibit inward rectification because of a fast C-type inactivation mechanism, but the slower rate of inactivation and the faster rate of activation results in less inward rectification than that observed in HERG channels. This characterization of Melk currents should aid in identification of native counterparts to the Elk subfamily of channels in the nervous system.
Gap-coupled series-fed antenna array with improved bandwidth

This paper presents the design of gap-coupled series fed antenna array with improved bandwidth. The series-fed array is designed using `U' shaped microstrip feed lines and parasitic elements gap-coupled to non-radiating edges of the central elements. The fabricated 3 element gap-coupled series-fed array has VSWR <;2 bandwidth of 5.5%, achieving 3 times improvement in bandwidth as compared to conventional array. The 3 element gap-coupled series-fed array has maximum gain of 13.1 dBi at 5.75 GHz and cross-polar levels <;27 dB.
D-branes and the noncommutative torus

We show that in certain superstring compactifications, gauge theories on noncommutative tori will naturally appear as D-brane world-volume theories. This gives strong evidence that they are well-defined quantum theories. It also gives a physical derivation of the identification proposed by Connes, Douglas and Schwarz of Matrix theory compactification on the noncommutative torus with M theory compactification with constant background three-form tensor field.
Global Culture Industry: The Mediation of Things

In the first half of the twentieth century, Theodor Adorno wrote about the 'culture industry'. For Adorno, culture too along with the products of factory labour was increasingly becoming a commodity. Now, in what they call the 'global culture industry', Scott Lash and Celia Lury argue that Adorno's worst nightmares have come true. Their new book tells the compelling story of how material objects such as watches and sportswear have become powerful cultural symbols, and how the production of symbols, in the form of globally recognized brands, has now become a central goal of capitalism. Global Culture Industry provides an empirically and theoretically rich examination of the ways in which these objects - from Nike shoes to Toy Story, from global football to conceptual art - metamorphose and move across national borders. This book is set to become a dialectic of enlightenment for the age of globalization. It will be essential reading for students and scholars across the social sciences.