Miracle-dz/UniFAR-FTUs huggingface dataset:
Maximal sustainable energy intake during transatlantic ocean rowing is insufficient for total energy expenditure and skeletal muscle mass maintenance.

Studies of extreme endurance have suggested that there is an alimentary limit to energy intake (EI) of ∼2.5 × resting metabolic rate (RMR). To gain further insight, this study aimed to simultaneously measure EI, total energy expenditure (TEE) body mass and muscle mass in a large cohort of males and females of varying ages during a transatlantic rowing race. Forty-nine competitors (m = 32, f = 17; age 24-67 years; time at sea 46 ± 7 days) in the 2020 and 2021 Talisker Whisky Atlantic Challenge rowed 12-18 hday-1 for ∼3000 miles. TEE was assessed in the final week of the row using 2 H2 18 O doubly labelled water, and EI was analysed from daily ration packs over this period. Thickness of relatively active (vastus lateralis, intermedius, biceps brachaii and rectus abdominus) and inactive (gastrocnemius, soleus and triceps) muscles was measured pre (<7 days) and post (<24 h) row using ultrasound. Body mass was measured and used to calculate RMR from standard equations. There were no sex differences in males and females in EI (2.5 ± 0.5 and 2.3 ± 0.4 × RMR, respectively, P = 0.3050), TEE (2.5 ± 1.0 and 2.3 ± 0.4 × RMR, respectively, P = 0.5170), or body mass loss (10.2 ± 3.1% and 10.0 ± 3.0%, respectively, P = 0.8520), and no effect of age on EI (P = 0.5450) or TEE (P = 0.9344). Muscle loss occurred exclusively in the calf (15.7% ± 11.4% P < 0.0001), whilst other muscles remained unchanged. After 46 days of prolonged ultra-endurance ocean rowing incurring 10% body mass loss, maximal sustainable EI of ∼2.5 × RMR was unable to meet total TEE suggesting that there is indeed a physiological capacity to EI. NEW FINDINGS: What is the central question of this study? During a prolonged endurance transatlantic ocean rowing race over ∼46 days, what changes occur in energy intake (EI), total energy expenditure (TEE) and body mass and are there differences between males and females or an effect of age? What is the main finding and its importance? During a ∼46 days, there appeared to be a maximal sustainable EI of ∼2.5 × resting metabolic rate (RMR), matching TEE of 2.5 × RMR, incurring a 10% body mass loss There were no sex differences, and minimal influence of age.
Population Viability Analysis for Northern Fur Seals (Callorhinus ursinus) in Canada Analyse de la viabilité de la population d'otaries à fourrure du Nord (Callorhinus ursinus) au Canada

iii RÉSUMÉ. iv INTRODUCTION.1 DEVELOPMENT OF PVA MODEL.2 OVERVIEW.2 POPULATION UNIT . 2 PVA MODEL.3 RECENT TRENDS . 4 MEASUREMENT ERROR AND NATURAL VARIATION.4 PROJECTIONS . 5 EXTINCTION THRESHOLD.6 MIGRATION PATTERNS . 8 TOTAL ABUNDANCE.11 RESULTS.12 DISCUSSION.13 ACKNOWLEDGEMENTS . 16 LITERATURE CITED.17 Correct citation for this publication: Olesiuk, P.F. 2012. Population viability analysis for northern fur seals (Callorhinus ursinus) in Canada. DFO Can. Sci. Advis. Sec. Res. Doc. 2012/041. iv + 36 p.
Midterm Clinical Outcomes, Radiographic Outcomes, and Survivorship of the Infinity Total Ankle Arthroplasty

Background: The Infinity Total Ankle Arthroplasty (Stryker, Mahwah, NJ) is a low-profile fixed-bearing implant first introduced in 2014. Although the short-term survivorship (2-4 years follow-up) and complication rates of the Infinity TAA have been reported, there are limited midterm outcome reports. The aim of this study was to describe the survivorship and clinical outcomes of a single-center experience with the Infinity implant at minimum 5-year follow-up. Methods: Retrospective review of 65 ankles that underwent primary total ankle arthroplasty (TAA) with the Infinity implant was conducted. Mean clinical follow-up was 6.5 years (range, 5.0-8.0). Preoperative and postoperative radiographs were measured to assess tibiotalar alignment, periprosthetic lucencies, and cysts. Preoperative, 2-year, and 5-year postoperative Foot and Ankle Outcome Score (FAOS) subscores were compared to assess midterm clinical outcomes. Survivorship assessment was determined by removal of 1 or both metallic implant components. Results: Survivorship of the implant was 93.8% at final follow-up. There were 4 revisions: 2 for tibial implant loosening, 1 for talar loosening, and 1 for loosening of both components. Three of the 4 revisions occurred within the first 2 years following implantation, and the last failure occurred at 7 years postoperatively. There were 11 reoperations in 10 (15%) ankles and 3 wound complications. There were 17 ankles (26.2%) with radiographic abnormalities around the implants, including 14 cases with tibial component lucencies and 4 cases of periimplant cysts. FAOS outcome measurement showed general stability between 2 and 5 years and substantial improvement from preoperative status. Conclusion: To date this study is the largest midterm report on the Infinity total ankle prosthesis, with 65 implants at a mean follow-up of 6.5 years. We found good midterm implant survivorship, and patients experienced significant improvements in FAOS outcome scores and radiographic alignment at final follow-up. Level of Evidence: Level III, retrospective cohort study.
Multiantigen print immunoassay (MAPIA) for the diagnosis of neurocysticercosis: a single-center diagnostic optimization and accuracy study in Lima, Peru

ABSTRACT Neurocysticercosis (NCC) is the most common helminthic infection of the human central nervous system. The antibody detection assay of choice is the enzyme-linked immunoelectrotransfer blot assay using lentil-lectin purified parasite antigens (LLGP-EITB, Western blot), an immunoassay with exceptional performance in clinical samples. However, its use is mainly restricted to a few research laboratories because the assay is labor-intensive and requires sophisticated equipment, expertise, and large amounts of parasite material for preparation of reagents. We report a new immunoprint assay (MAPIA) that overcomes most of these barriers. We initially compared the performance of five different antigen combinations in a subset of defined samples in the MAPIA format. After selecting the best-performing assay format (a combination of rGP50 + rT24H + sTs14 antigens), 148 archived serum samples were tested, including 40 from individuals with parenchymal NCC, 40 with subarachnoid NCC, and 68 healthy controls with no evidence of neurologic disease. MAPIA using three antigens (rGP50 + rT24H + sTs14) was highly sensitive and specific for detecting antibodies in NCC. It detected 39 out of 40 (97.5%) parenchymal NCC cases and 40/40 (100%) subarachnoid cases and was negative in 67 out of 68 (98.53%) negative samples. MAPIA using three recombinant and synthetic antigens is a simple and economical tool with a performance equivalent to the LLGP-EITB assay for the detection of specific antibodies to NCC. The MAPIA overcomes existing barriers to adoption of the EITG LLGP and is a candidate for worldwide use.
Fear of falling in women: A psychological training intervention improves climbing performance

ABSTRACT The main purpose of this study was to determine the effect of a psychological training intervention based on emotional regulation on anxiety and climbing ability in women climbers with fear of falling. A secondary aim was to compare the outcomes of climbing ability, anxiety, self-confidence and interoceptive awareness (IA) between the psychological group (PG), a training (TG) and a control group. Self-reported climbing ability, anxiety and IA were assessed using Competitive State Anxiety Inventory-2 and the Multidimensional Assessment of Interoceptive Awareness questionnaire. Results indicated a significant improvement in climbing ability for both PG and TG. The PG showed a significant reduction in cognitive and somatic anxiety, while the TG only exhibited a reduction in cognitive anxiety. Moreover, the PG demonstrated a greater significant increase in self-confidence compared to the TG. IA improved in five subscales for the PG, whereas the TG changed in only two subscales. In conclusion, a psychological training intervention focusing on emotional regulation might contribute to improvements in IA, reduced anxiety levels, and enhancements in climbing ability and self-confidence among women climbers facing fear of falling.
Efficacy of amorphous TiOx-coated surfaces against micro- and macrofouling through laboratory microcosms and field studies

Abstract In this study, Soda Lime Glass (SLG) and Stainless Steel (SS316L) substrata coated with Titanium oxide (TiOx) were tested for their efficacy in the laboratory microcosms and in field against micro- and macrofouling. Laboratory microcosm studies were conducted for five days using natural biofilms, single-species diatom (Navicula sp.), and bacterial biofilms, whereas field observations were conducted for 30 days. The TiOx-coating induced change in the mean contact angle of the substratum and rendered SS316L more hydrophilic and SLG hydrophobic, which influenced the Navicula sp. biofilm, and bacterial community structure of the biofilm. Overall, the TiOx-coated SS316L showed minimal microfouling, whereas non-coated SLG exhibited greater efficacy in deterring/preventing macrofouling organisms. Moreover, the reduction in macrofouling could be attributed to high abundance of Actinobacteria. Unraveling the mechanism of action needs future studies emphasizing biochemical processes and pathways.
Experimental models for HIV latency and molecular tools for reservoir quantification—an update

SUMMARY A major impediment for HIV cure is the ability of the virus to integrate its genome in the form of replication-competent proviral DNA into the cellular genome of the host and remain transcriptionally silent and hidden from the host’s immune defense mechanisms in latent reservoir cells. These latent reservoirs are highly heterogeneous, long-lived cells that are capable of reactivating to restore the viremic stage in virally suppressed individuals upon treatment interruption, thus necessitating life-long antiretroviral treatment. Latency reversal has become one of the most explored therapeutic approaches for eliminating HIV reservoirs and effecting HIV cure. Various aspects governing the establishment, maintenance, and reversal of HIV latency continue to be an enigma and warrant further research. Quantifying the size of the latent reservoir pool is also a challenge as these cells are very few in number and cannot be easily differentiated from uninfected cells. This article provides a comprehensive review of the in vitro and in vivo models currently available for studying HIV latency as well as the recently developed molecular tools for detection and quantification of latent viral reservoirs.
Combined transcranial magnetic stimulation and electroencephalography reveals alterations in cortical excitability during pain

Transcranial magnetic stimulation (TMS) has been used to examine inhibitory and facilitatory circuits during experimental pain and in chronic pain populations. However, current applications of TMS to pain have been restricted to measurements of motor evoked potentials (MEPs) from peripheral muscles. Here, TMS was combined with electroencephalography (EEG) to determine whether experimental pain could induce alterations in cortical inhibitory/facilitatory activity observed in TMS-evoked potentials (TEPs). In Experiment 1 (n=29), multiple sustained thermal stimuli were administered to the forearm, with the first, second, and third block of thermal stimuli consisting of warm but non-painful (pre-pain block), painful (pain block) and warm but non-painful (post-pain block) temperatures, respectively. During each stimulus, TMS pulses were delivered while EEG (64 channels) was simultaneously recorded. Verbal pain ratings were collected between TMS pulses. Relative to pre-pain warm stimuli, painful stimuli led to an increase in the amplitude of the frontocentral negative peak ~45 ms post-TMS (N45), with a larger increase associated with higher pain ratings. Experiments 2 and 3 (n=10 in each) showed that the increase in the N45 in response to pain was not due to changes in sensory potentials associated with TMS, or a result of stronger reafferent muscle feedback during pain. This is the first study to use combined TMS-EEG to examine alterations in cortical excitability in response to pain. These results suggest that the N45 TEP peak, which indexes GABAergic neurotransmission, is implicated in pain perception and is a potential marker of individual differences in pain sensitivity.
Upwelling of deep water during thermal stratification onset—A major mechanism of vertical transport in small temperate lakes in spring?

Using airborne thermal infrared imaging and horizontally resolved in situ temperature monitoring at the lake surface, we estimated strength and duration of regular wind‐driven upwelling of dense deep water to the lake surface in two small (in terms of Rossby radius) temperate lakes during the initial phase of summer thermal stratification. The onset and duration of the upwelling events correlated well with the balance between stratification (in terms of Schmidt stability) and wind forcing, as expressed by Lake and Wedderburn numbers. The period of regular upwelling appearances lasted 7–15 days, identified by Schmidt stabilities around 30 J m−2 and Lake numbers between 0 and 1, and resulted in persistent temperature gradients of up to 2°C across the lake surface. Our results suggest that spring upwelling should inevitably take place in all freshwater temperate lakes with mean temperatures crossing the maximum density value of freshwater on annual cycle, whereas duration and intensity of the upwelling would vary depending on lake morphometry and weather conditions. Our results suggest major contribution of upwelling in nutrient supply to the upper waters, oxygenation of the deep water column, and air‐lake gas exchange, in particular, the release of the sediment‐produced methane into the atmosphere.
Exploration of the Assessment for AVP Algorithm Training in Underground Parking Garages Simulation Scenario

The autonomous valet parking (AVP) functionality in self-driving vehicles is currently capable of handling most simple parking tasks. However, further training is necessary to enable the AVP algorithm to adapt to complex scenarios and complete parking tasks in any given situation. Training algorithms with real-world data is time-consuming and labour-intensive, and the current state of constructing simulation environments is predominantly manual. This paper introduces an approach to automatically generate 3D underground garage simulation scenarios of varying difficulty levels based on pre-input 2D underground parking structure plans.
Quartz From the Tipuma Formation, West Papua: New Insights from Geochronology and Cathodoluminescence Studies

The Tipuma Formation is one of several quartz-rich sandstone formations from the Bird’s Head. Its age has been estimated as Triassic to Jurassic based on its stratigraphic position and it has been interpreted as derived from a continental source. The age estimate is supported new U-Pb dating of detrital zircons but studies of light and heavy minerals, quartz cathodoluminescence and zircon age data suggest a more complex provenance. Acid plutonic, and sedimentary rocks were derived from the North Australian continent but angular quartz and elongate euhedral zircons indicate a contribution from previously importance of volcanic quartz is supported which variations during The CL spectra of sandstones from the Lower, Middle Upper Members of the Tipuma Formation show they are dominated by quartz of low-T metamorphic and volcanic origin with little plutonic quartz. This is correlated with a decline in Permo–Triassic zircons and an increase in Carboniferous and Proterozoic zircons. We interpret this to indicate a reduced contribution of sediment from the arc and an increased contribution of sediment from northern Australia. A small number of sandstone samples assigned to the Tipuma Formation from the Bird’s Body have also been studied. These are dominated by quartz of low-T metamorphic origin with subordinate volcanic and plutonic quartz. Geochronological results show Triassic zircons are absent but other zircon populations are similar to the Bird’s Head. The differences between sandstones of the Bird’s Head and Body could be explained if the Bird’s Body sandstones are Permian in age and not correlatives of the Tipuma Formation. However, these sandstones resemble the Middle Member of the Bird’s Head Tipuma Formation and their character is consistent with their geographic location which would have been much further from the northern Andean arc but much closer to the northern Australia continent.
XplainLLM: A QA Explanation Dataset for Understanding LLM Decision-Making

Large Language Models (LLMs) have recently made impressive strides in natural language understanding tasks. Despite their remarkable performance, understanding their decision-making process remains a big challenge. In this paper, we look into bringing some transparency to this process by introducing a new explanation dataset for question answering (QA) tasks that integrates knowledge graphs (KGs) in a novel way. Our dataset includes 12,102 question-answer-explanation (QAE) triples. Each explanation in the dataset links the LLM's reasoning to entities and relations in the KGs. The explanation component includes a why-choose explanation, a why-not-choose explanation, and a set of reason-elements that underlie the LLM's decision. We leverage KGs and graph attention networks (GAT) to find the reason-elements and transform them into why-choose and why-not-choose explanations that are comprehensible to humans. Through quantitative and qualitative evaluations, we demonstrate the potential of our dataset to improve the in-context learning of LLMs, and enhance their interpretability and explainability. Our work contributes to the field of explainable AI by enabling a deeper understanding of the LLMs decision-making process to make them more transparent and thereby, potentially more reliable, to researchers and practitioners alike. Our dataset is available at: https://github.com/chen-zichen/XplainLLM_dataset. git
Controllable Text Summarization: Unraveling Challenges, Approaches, and Prospects - A Survey

Generic text summarization approaches often fail to address the specific intent and needs of individual users. Recently, scholarly attention has turned to the development of summarization methods that are more closely tailored and controlled to align with specific objectives and user needs. While a growing corpus of research is devoted towards a more controllable summarization, there is no comprehensive survey available that thoroughly explores the diverse controllable aspects or attributes employed in this context, delves into the associated challenges, and investigates the existing solutions. In this survey, we formalize the Controllable Text Summarization (CTS) task, categorize controllable aspects according to their shared characteristics and objectives, and present a thorough examination of existing methods and datasets within each category. Moreover, based on our findings, we uncover limitations and research gaps, while also delving into potential solutions and future directions for CTS.
K-BMPC: Derivative-based Koopman Bilinear Model Predictive Control For Tractor-trailer Trajectory Tracking With Unknown Parameters

Nonlinear dynamics bring difficulties to controller design for control-affine systems such as tractor-trailer vehicles, especially when the parameters in dynamics are unknown. To address this constraint, we propose a derivative-based lifting function construction method, show that the corresponding infinite dimensional Koopman bilinear model over the lifting function is equivalent to the original control-affine system. Further, we analyze the propagation and bounds of state prediction errors caused by the the truncation in derivative order. The identified finite dimensional Koopman bilinear model would serve as predictive model in next step. Koopman Bilinear Model Predictive control (K-BMPC) is proposed to solve the trajectory tracking problem. We linearize the bilinear model around the estimation of the lifted state and control input. Then the bilinear Model Predictive Control problem is approximated by a quadratic programming problem. Further, the estimation is updated at each iteration until the convergence is reached. Moreover, we implement our algorithm on a tractor-trailer dynamic system, taking into account the longitudinal and side slip effects. The open-loop simulation shows the proposed Koopman bilinear model captures the dynamics with unknown parameters and has good prediction performance. Closed loop tracking results show the proposed K-BMPC exhibits elevated tracking precision along with commendable computational efficiency. The experimental results demonstrate the feasibility of the proposed method.
Use of Polyphosphate to Decrease Uranium Leaching in Hanford 300 Area Smear Zone Sediments

The primary objective of this study is to summarize the laboratory investigations performed to evaluate short- and long-term effects of phosphate treatment on uranium leaching from 300 area smear zone sediments. Column studies were used to compare uranium leaching in phosphate-treated to untreated sediments over a year with multiple stop flow events to evaluate longevity of the uranium leaching rate and mass. A secondary objective was to compare polyphosphate injection, polyphosphate/xanthan injection, and polyphosphate infiltration technologies that deliver phosphate to sediment.
Evaluating Gender Bias in the Translation of Gender-Neutral Languages into English

Machine Translation (MT) continues to improve in quality and adoption, yet the inadvertent perpetuation of gender bias remains a significant concern. Despite numerous studies into gender bias in translations from gender-neutral languages such as Turkish into more strongly gendered languages like English, there are no benchmarks for evaluating this phenomenon or for assessing mitigation strategies. To address this gap, we introduce GATE X-E, an extension to the GATE (Rarrick et al., 2023) corpus, that consists of human translations from Turkish, Hungarian, Finnish, and Persian into English. Each translation is accompanied by feminine, masculine, and neutral variants for each possible gender interpretation. The dataset, which contains between 1250 and 1850 instances for each of the four language pairs, features natural sentences with a wide range of sentence lengths and domains, challenging translation rewriters on various linguistic phenomena. Additionally, we present an English gender rewriting solution built on GPT-3.5 Turbo and use GATE X-E to evaluate it. We open source our contributions to encourage further research on gender debiasing.
Data Downloaded via Parachute from a NASA Super-Pressure Balloon

In April 2023, the superBIT telescope was lifted to the Earth’s stratosphere by a helium-filled super-pressure balloon to acquire astronomical imaging from above (99.5% of) the Earth’s atmosphere. It was launched from New Zealand and then, for 40 days, circumnavigated the globe five times at a latitude 40 to 50 degrees south. Attached to the telescope were four “drs” (Data Recovery System) capsules containing 5 TB solid state data storage, plus a gnss receiver, Iridium transmitter, and parachute. Data from the telescope were copied to these, and two were dropped over Argentina. They drifted 61 km horizontally while they descended 32 km, but we predicted their descent vectors within 2.4 km: in this location, the discrepancy appears irreducible below ∼2 km because of high speed, gusty winds and local topography. The capsules then reported their own locations within a few metres. We recovered the capsules and successfully retrieved all of superBIT’s data despite the telescope itself being later destroyed on landing.