Miracle-dz/UniFAR-FTUs huggingface dataset:
Wirtschaftinformatik 1-1-2009 SUPPORTING INVESTMENT MANAGEMENT PROCESSES WITH MACHINE LEARNING TECHNIQUES

IT support and especially IT innovations represent crucial success factors in investment management and financial decision making. The application of machine learning techniques for intraday decision support constitutes such a crucial factor, but existing literature has not been capable of melding latest research results from both the text and the capital market research field. Combining fundamental research results from both domains, it is possible to develop a forecasting model that performs better than both alternative internal (random) benchmarks and external prior research benchmarks. The approach is tested by means of “classical” evaluation methods such as well as by a simulation.
Aquaglyceroporin 2 controls susceptibility to melarsoprol and pentamidine in African trypanosomes

African trypanosomes cause sleeping sickness in humans, a disease that is typically fatal without chemotherapy. Unfortunately, drug resistance is common and melarsoprol-resistant trypanosomes often display cross-resistance to pentamidine. Although melarsoprol/pentamidine cross-resistance (MPXR) has been an area of intense interest for several decades, our understanding of the underlying mechanisms remains incomplete. Recently, a locus encoding two closely related aquaglyceroporins, AQP2 and AQP3, was linked to MPXR in a high-throughput loss-of-function screen. Here, we show that AQP2 has an unconventional “selectivity filter. ” AQP2-specific gene knockout generated MPXR trypanosomes but did not affect resistance to a lipophilic arsenical, whereas recombinant AQP2 reversed MPXR in cells lacking native AQP2 and AQP3. AQP2 was also shown to be disrupted in a laboratory-selected MPXR strain. Both AQP2 and AQP3 gained access to the surface plasma membrane in insect life-cycle–stage trypanosomes but, remarkably, AQP2 was specifically restricted to the flagellar pocket in the bloodstream stage. We conclude that the unconventional aquaglyceroporin, AQP2, renders cells sensitive to both melarsoprol and pentamidine and that loss of AQP2 function could explain cases of innate and acquired MPXR.
Reliability of a Silicon Stacked Module for 3-D SiP Microsystem

Solder joint reliability of 3-D silicon carrier module were investigated with temperature cycle and drop impact test. Mechanical simulation was carried out to investigate the solder joint stress using finite element method (FEM), whose 3-D model was generated and solder fatigue model was used. According to the simulation results, the stress involved between flip chip and Si substrate was negligible but stress is more concentrated between Si carriers to printed circuit board (PCB) solder joint area. Test vehicles were fabricated using silicon fabrication processes such as DRIE, Cu via plating, SiO deposition, metal deposition, lithography, and dry or wet etching. After flip chip die and silicon substrate fabrication, they were assembled by flip chip bonding equipment and 3-D silicon stacked modules with three silicon substrate and flip chip dies were fabricated. Daisy chains were formed between flip chip dies and silicon substrate and resistance measurement was carried out with temperature cycle test (C, 2 cycles/h). The tested flip chip test vehicles passed T/C 5000 cycles and showed robust solder joint reliability without any underfill material. Drop test was also carried out by JEDEC standard method. More details on test vehicle fabrication and reliability test results would be presented in the paper.
Does malaria control impact education? A study of the Global Fund in Africa

We examine the middle-run eff ects of the Global Fund's malaria control programs on the educational attainment of primary schoolchildren in Sub-Saharan Africa. Using a quasi-experimental approach, we exploit geographic variation in pre-campaign malaria prevalence (malaria ecology) and variation in exogenous exposure to the timing and expenditure of malaria control campaigns, based on individuals' years of birth and year surveyed. In a large majority of countries (14 of 22), we find that the program led to substantial increases in years of schooling and grade level as well as reductions in schooling delay. These countries are those for which pre-campaign educational resources are the highest. Moreover, although by and large positive, we nd that the marginal returns of the Global Fund disbursements in terms of educational outcomes are decreasing. Our findings, which are robust to both the instrumentation of ecology and use of alternative ecology measures, have important policy implications on the value for money of malaria control eff orts.
Driving Cessation and Self-Reported Car Crashes in Older Drivers: The Impact of Cognitive Impairment and Dementia in a Population-Based Study

The complexity of driving activity has incited numerous developed countries to initiate evaluative procedures in elderly people, varying according to first evaluation age, frequency, and screening tools. The objective of this paper is to improve the knowledge of the driving cessation process regarding factors associated with crash involvement. Driving cessation and self-reported crashes during the past 5 years were analyzed with multivariate models, in a cross-sectional study including a population-based sample of 1051 drivers aged 65 years and more. Visual trouble, Parkinson disease, dementia, and stroke history were associated with driving cessation. Future dementia was associated with self-reported crashes only. Attentional and executive deficits were associated with both outcomes. The detection of attentional and executive deficits should be included in driving evaluation procedures to improve awareness of these deficits by older drivers.
Oxidative stress effects of thinner inhalation

Thinners are chemical mixtures used as industrial solvents. Humans can come into contact with thinner by occupational exposure or by intentional inhalation abuse. Thinner sniffing causes damage to the brain, kidney, liver, lung, and reproductive system. We discuss some proposed mechanism by which thinner induces damage. Recently, the induction of oxidative stress has been suggested as a possible mechanism of damage. This paper reviews the current evidence for oxidative stress effects induced by thinner inhalation. Early ideas about the effects of thinner on lipids are discussed in one section. We discuss several studies that have shown the oxidative effects of thinner inhalation on: lipid peroxidation, levels of antioxidant enzymes, glutathione depletion, and oxidation of proteins and DNA. We have also included studies about oxidative stress effects induced by toluene, the principal component (60-70%) of thinner. Finally, work describing the effects of oxidative stress induced by thinner inhalation on different organs is discussed.
The Pleasure Evoked by Sad Music Is Mediated by Feelings of Being Moved

Why do we enjoy listening to music that makes us sad? This question has puzzled music psychologists for decades, but the paradox of “pleasurable sadness” remains to be solved. Recent findings from a study investigating the enjoyment of sad films suggest that the positive relationship between felt sadness and enjoyment might be explained by feelings of being moved (Hanich et al., 2014). The aim of the present study was to investigate whether feelings of being moved also mediated the enjoyment of sad music. In Experiment 1, 308 participants listened to five sad music excerpts and rated their liking and felt emotions. A multilevel mediation analysis revealed that the initial positive relationship between liking and felt sadness (r = 0.22) was fully mediated by feelings of being moved. Experiment 2 explored the interconnections of perceived sadness, beauty, and movingness in 27 short music excerpts that represented independently varying levels of sadness and beauty. Two multilevel mediation analyses were carried out to test competing hypotheses: (A) that movingness mediates the effect of perceived sadness on liking, or (B) that perceived beauty mediates the effect of sadness on liking. Stronger support was obtained for Hypothesis A. Our findings suggest that – similarly to the enjoyment of sad films – the aesthetic appreciation of sad music is mediated by being moved. We argue that felt sadness may contribute to the enjoyment of sad music by intensifying feelings of being moved.
The influence of parent concrete and milling intensity on the properties of recycled aggregates

The C2CA concrete recycling process consists of a combination of smart demolition, gentle grinding of the crushed concrete in an autogenous mill, and a novel dry classification technology called ADR to remove the fines. The` main factors in the C2CA process which influence the properties of Recycled Aggregates or Recycled Aggregate Concrete (RAC) include the type of Parent Concrete (PC), the intensity of autogenous milling and ADR cut-size point. This study aims to investigate the influence of PC and intensity of the autogenous milling on the quality of the produced recycled aggregates. Three types of concrete which are frequently demanded in the Dutch market were cast as PC and their fresh and hardened properties were tested. After near one year curing of PC samples, they were recycled independently while the aforementioned recycling factors were varied. The effects of different recycling variables on the water absorption, density, crushing resistance and durability of produced recycled aggregates were investigated. According to the results, type of the parent concrete is the predominant factor influencing the properties of the recycled aggregates. Milling intensity was found to be effective on improving the properties of recycled aggregates coming from weaker parent concrete. The experimental results suggest that among various milling intensities, milling at medium shear and medium compression improves the overall quality of RA
Tomato Chlorotic Mottle Virus Is a Target of RNA Silencing but the Presence of Specific Short Interfering RNAs Does Not Guarantee Resistance in Transgenic Plants

ABSTRACT Tomato chlorotic mottle virus (ToCMoV) is a begomovirus found widespread in tomato fields in Brazil. ToCMoV isolate BA-Se1 (ToCMoV-[BA-Se1]) was shown to trigger the plant RNA silencing surveillance in different host plants and, coinciding with a decrease in viral DNA levels, small interfering RNAs (siRNAs) specific to ToCMoV-[BA-Se1] accumulated in infected plants. Although not homogeneously distributed, the siRNA population in both infected Nicotiana benthamiana and tomato plants represented the entire DNA-A and DNA-B genomes. We determined that in N. benthamiana, the primary targets corresponded to the 5′ end of AC1 and the embedded AC4, the intergenic region and 5′ end of AV1 and overlapping central part of AC5. Subsequently, transgenic N. benthamiana plants were generated that were preprogrammed to express double-stranded RNA corresponding to this most targeted portion of the virus genome by using an intron-hairpin construct. These plants were shown to indeed produce ToCMoV-specific siRNAs. When challenge inoculated, most transgenic lines showed significant delays in symptom development, and two lines had immune plants. Interestingly, the levels of transgene-produced siRNAs were similar in resistant and susceptible siblings of the same line. This indicates that, in contrast to RNA viruses, the mere presence of transgene siRNAs corresponding to DNA virus sequences does not guarantee virus resistance and that other factors may play a role in determining RNA-mediated resistance to DNA viruses.
Minimally invasive transforaminal lumbar interbody fusion using bone cement-augmented pedicle screws for lumbar spondylolisthesis in patients with osteoporosis. Case series and review of literature

Background: Instrumentation in patients with osteoporosis is challenging. Bone cement-augmented fenestrated pedicle screw fixation is a new procedure for fixation in the osteoporotic bone; and, applying minimally invasive techniques to the above is a challenging and novel concept. Aims: To evaluate the clinical and radiological outcome of minimally invasive spine surgery transforaminal lumbar interbody fusion (MIS-TLIF) in patients with spondylolisthesis and poor bone quality, performed with rigid instrumentation using bone cement [poly(methylmethacrylate)]-augmented fenestrated pedicle screws. Settings and Design: Prospective, observational, single-center study. Statistical Analysis Used: Wilcoxon nonparametric test for paired samples with a level of significance of 0.05. Methods: A clinical series of 25 patients with lumbar spondylolisthesis and osteoporosis who underwent minimally invasive TLIF with bone cement-augmented pedicle screws were included in the study. Clinical outcome and the function were assessed using the visual analog scale (VAS) score for pain and the Oswestry Disability Index (ODI). Perioperative, postoperative, and long-term complications were monitored with a mean follow-up of 18 months. Results: A total of 25 (20 female and 5 male) patients were included in the study with an average age of 61.05 years. The major symptom was low back pain with radiating pain to lower limbs. The average T-score was −3.0. All the patients were followed clinically and radiologically. There was a statistically significant improvement in the VAS scores and ODI scores postoperatively. No events of cement extravasation, radiological loosening, or pulling out of screws were observed. Conclusions: Fenestrated pedicle screw fixation with bone cement augmentation in patients with osteoporosis is a well-established alternative to increase the pullout strength of screws placed in the osteoporotic bone. Applying the concept of minimally invasive surgery to this procedure makes it a more complete solution for instrumentation in osteoporotic spine. Our series is the largest in literature on spondylolisthesis and confirms the feasibility and safety of this procedure in treating spondylolisthesis in the aging population.
A General ADE-FDTD Algorithm for the Simulation of Dispersive Structures

A finite-difference time-domain general algorithm, based on the auxiliary differential equation (ADE) technique, for the analysis of dispersive structures is presented. The algorithm is suited for cases where materials having different types of dispersion are modeled together. While having the same level of accuracy, the proposed algorithm finds its strength in unifying the formulation of different dispersion models into one form. Consequently, savings in both memory and computational requirements, compared to other ADE-based methods that model each dispersion type separately, are possible. The algorithm is applied in the simulation of surface plasmon polaritons using the multipole Lorentz-Drude dispersion model of silver.
ANONYMIZATION BASED ON NESTED CLUSTERING FOR PRIVACY PRESERVATION IN DATA MINING

Privacy Preservation in data mining protects the data from revealing unauthorized extraction of information. Data Anonymization techniques implement this by modifying the data, so that the original values cannot be acquired easily. Perturbation techniques are variedly used which will greatly affect the quality of data, since there is a trade-off between privacy preservation and information loss which will subsequently affect the result of data mining. The method that is proposed in this paper is based on nested clustering of data and perturbation on each cluster. The size of clusters is kept optimal to reduce the information loss. The paper explains the methodology, implementation and results of nested clustering. Various metrics are also provided to explicate that this method overcomes the disadvantages of other perturbation methods.
Multiple Equilibria in Complex Chemical Reaction Networks: I. The Injectivity Property

The capacity for multiple equilibria in an isothermal homogeneous continuous flow stirred tank reactor is determined by the reaction network. Examples show that there is a very delicate relationship between reaction network structure and the possibility of multiple equilibria. We suggest a new method for discriminating between networks that have the capacity for multiple equilibria and those that do not. Our method can be implemented using standard computer algebra software and gives answers for many reaction networks for which previous methods give no information.
oMAP: An Implemented Framework for Automatically Aligning OWL Ontologies

This paper introduces oMAP, a method and a tool for automatically aligning OWL ontologies, a crucial step for achieving the interoperability of heterogeneous systems in the Semantic Web. Different components are combined for finding suitable mapping candidates (together with their weights), and the set of rules with maximum matching probability is selected. Terminological, machine learning-based classifiers and a new classifier using the structure and the semantics of the OWL ontologies are proposed. Our method has been implemented and evaluated on an independent test set provided by the ontology alignment evaluation initiative (OAEI). We provide the results of this evaluation for the various contests with respect to the other competitors.
Programmable Contact Printing Using Ballpoint Pens with a Digital Plotter for Patterning Electrodes on Paper

A simple programmable contact printing method using ballpoint pens with silver nanoparticle (AgNP) and carbon nanotube (CNT) ink and a digital plotter were developed for quick patterning of electrodes on paper. This printing method enables sequential and programmable printing with two different inks and with ink consisting of high viscosity materials and is amenable to reproducibility of printed electrodes and customized designs. With this printing method, AgNP and CNT patterns with low electrical resistance and high density of the material can be printed. Using these AgNP and CNT inks, we fabricated disposable electrochemical sensors (ECSs) on paper. The ECSs were successfully used to detect glucose at various concentrations from 0 to 15 mM. The characteristics of the printed AgNP and CNT patterns, such as the printing resolution, surface morphology, and electrical properties, were also studied. The proposed contact printing method opens an avenue for printing paper-based electronics and devices.
Diastolic Function Predicts Outcome After Aortic Valve Replacement in Patients with Chronic Severe Aortic Regurgitation

Due to eccentric hypertrophy and fibrosis, patients with severe aortic regurgitation (AR) have diastolic dysfunction. Increased fibrosis correlates with increased myocardial stiffness and worsening of diastolic function. Patients with irreversible left ventricular (LV) dysfunction have severe myocardial fibrosis and myocyte apoptosis and do not benefit from aortic valve replacement (AVR).
Intrinsic Local Symmetries: A Computational Framework

We present a computational framework for finding metric-preserving tangent vector fields on surfaces, also known as Killing Vector Fields. Flows of such vector fields define self-isometries of the surface, or in other words, symmetries. Our approach is based on general-purpose isometry-finding frameworks, and is shown to be robust to noise. In addition, we demonstrate symmetry recovery using non-Euclidean metrics.
Gender in Play: Mapping a Girls' Gaming Club

To better understand boys’ privilege and girls’ educational disadvantage with regard to video games, this presentation aims to challenge the ways girl gamers are rendered invisible by gaming communities, researchers, and designers. Drawing from audiovisual research of a girls’ gaming club at an elementary school in Toronto, this paper explores the micro-interactions of a gaming session between five girls which is interrupted when two boys enter the scene and try to hijack their play. Using the MAP (Multimodal Application Program, developed by Suzanne de Castell and Jennifer Jenson) tool to visually chart and analyze the co-ordinated reactions of the girls as they put down their controllers and hold their bodies immobile during the boys’ disruption, this paper explores the tenuous relationship to video games these girls enjoy, even within a space ostensibly devoted to their play. Author Keywords gender, education, ethnography, social contexts CHARTING GENDER AND GAMING
European Conference on Information Systems ( ECIS ) 2010 Capturing Practices of Knowledge Work for Information Systems Design

Despite abundant tools and systems claiming support for knowledge work, many have failed to be accepted by users. Designing information systems (ISs) for knowledge work is a challenging task, but results on how knowledge work is actually performed is scarce and so are instruments that help to translate results into artefacts useful for IS design. This paper takes the perspective of work practices and proposes an approach to collaboratively study and analyze practices of knowledge work. The approach uses stereotypes of users, called personas, in order to inform IS design activities. The persona concept is enriched with respect to behaviour concerning practices of knowledge work. Furthermore, a procedure for selecting primary personas out of a set of personas is suggested based on cluster analysis. The approach is illustrated with the case of a collaborative ethnographically-informed study of seven organizations in four European countries. The proposed approach is the more suitable, the more innovative, big and diverse the project, the planned product, the developers and the target group are. User-centered design activities benefit from personas by reduced effort for involving end-users and a continuous focus on characteristics of critical users and their way of performing practices of knowledge work.
Increasing Voltage Utilization in Split-Link, Four-Wire Inverters

Three-phase four-wire inverters, with either three-leg or four-leg topology, are useful for interfacing distributed generation to networks of unbalanced loads, but neither of the available circuit topologies is ideal. The split-link three-leg topology (with six switches) suffers from poor DC voltage utilization compared with the four-leg topology (with eight switches). The four-leg topology has an electromagnetic compatibility (EMC) difficulty because it imposes large-amplitude high-frequency voltages between the DC-link busbars and ground. To obtain both good dc voltage utilization and good EMC performance, it is proposed to use a split-link inverter with an active balancing circuit (also eight switches). The balancing circuit is used to modulate the DC busbar offset voltage to make better use of the available DC-link voltage. The optimum voltage term is established to be a third harmonic term, and the DC voltage utilization is improved. A deadbeat controller supplemented with a repetitive controller is designed to give good tracking and good disturbance rejection for the busbar offset voltage. System performance is studied through an experimental test rig.