Miracle-dz/UniFAR-FTUs huggingface dataset:
How Discoloration of Porcine Cruor Hydrolysate Allowed the Identification of New Antifungal Peptides

Porcine blood is an important by-product from slaughterhouses and an abundant source of proteins. Indeed, cruor, the solid part of blood, is mainly composed of hemoglobin. Its enzymatic hydrolysis with pepsin generates a diversity of peptides, particularly antimicrobials. One of the downsides of using these hydrolysates as food bio-preservatives is the color brought by the heme, which can be removed by discoloration. Nonetheless, the effects of this procedure on the antimicrobial peptide population have not been completely investigated. In this study, its impacts were evaluated on the final antibacterial and antifungal activities of a cruor hydrolysate. The results demonstrated that 38 identified and characterized peptides showed a partial or total decrease in the hydrolysate, after discoloration. Antifungal activities were observed for the raw and discolored hydrolysates: MICs vary between 0.1 and 30.0 mg/mL of proteins, and significant differences were detected between both hydrolysates for the strains S. boulardii, C. guilliermondii, K. marxianus, M. racemosus and P. chrysogenum. The raw hydrolysate showed up to 12 times higher antifungal activities. Hence, peptides with the highest relative abundance decrease after discoloration were synthesized and tested individually. In total, eight new antifungal peptides were characterized as active and promising. To our knowledge, this is the first time that effective antifungal peptide sequences have been reported from porcine cruor hydrolysates.
Experimental Characterization of Additively Manufactured Multi-Feather Wingtip Devices

Soaring birds have evolved to fly for long periods of time without flapping their wings. Inspired by the flight of these birds, the proposed thesis presents an experimental investigation focused on wingtip devices designed based on biomimicry. The overarching engineering objective was to reduce the induced drag as a means to improve the fuel efficiency via these experimental wingtips. An associated secondary objective was to establish a method for manufacturing complex structures suitable for wing tunnel testing. A manufacturing technique that involved using composite weaves to reinforce additively manufactured structures was developed. This technique has the potential to reduce manufacturing times by as much as three weeks, when compared to traditional manufacturing methods. Three “featherlet” wing tip attachments were designed and manufactured. Surface flow visualization and force balance campaigns were then conducted at the ERAU Micaplex low speed wind tunnel. The surface streamlines from the oil surface flow visualization campaign showed that the basic winglet had flow over the wing that was closest to two-dimensional flow. This was reinforced by the analysis of the lift to drag ratio where the basic winglet had an increased aerodynamic efficiency of up to 25% over the wing with no attachment. Two of the three featherlets tested showed an improved aerodynamic efficiency as well as a significant reduction in induced drag when compared to the no attachment case. Data suggests that with further development, a featherlet attachment could one day perform better than the basic winglet attachment.
Chemical Modifications Influence the Number of siRNA Molecules Adsorbed on Gold Nanoparticles and the Efficiency of Downregulation of a Target Protein

Small interfering RNAs (siRNAs) are a powerful tool for specific suppression of protein synthesis in the cell, and this determines the attractiveness of siRNAs as a drug. Low resistance of siRNA to nucleases and inability to enter into target cells are the most crucial issues in developing siRNA-based therapy. To face this challenge, we designed multilayer nanoconstruct (MLNC) with AuNP core bearing chemically modified siRNAs. We applied chemical modifications 2′-OMe and 2′-F substitutions as well as their combinations with phosphoryl guanidine group in the internucleotide phosphate. The effect of modification on the efficiency of siRNA loading into nanocarriers was examined. The introduction of the internucleotide modifications into at least one of the strands raised the efficiency of siRNA adsorption on the surface of gold core. We also tested the stability of modified siRNA adsorbed on gold core in the presence of serum. Based on loading efficiency and stability, MLNCs with the most siRNA effective cargo were selected, and they showed an increase in biological activity compared to control MLNCs. Our study demonstrated the effect of chemical modifications of siRNA on its binding to the AuNP-based carrier, which directly affects the efficiency of target protein expression inhibition.
#MyIBDHistory on Twitter: Identifying Disease Characteristics Using Personal Tweets

Inflammatory bowel disease (IBD) is usually classified into Crohn's disease (CD) or ulcerative colitis (UC). Inconclusive cases are diagnosed with IBD unclassified (IBD-U). In 2018, IBD patients shared their disease history on Twitter and signed their tweets with #MyIBDHistory. In this research, we analyzed those tweets and built a logistic regression classifier that predicts patients' IBD type. We constructed tabular classification features and assessed their importance using the regression coefficients and association rules. We identified key features that distinguished CD from UC and used the classifier to predict the disease type of IBD-U patients. Our results correlated with IBD-related research. The two most prominent features that tilted the classification towards CD were suffering from fistulas or nutrient deficiencies. We identified gender differences in disease perspective prior to diagnosis. The research shows that the personal information shared by patients on Twitter can enhance existing medical knowledge regarding their disease.
On ( s , t ) -relaxed L ( 2 , 1 ) -labelings of the triangular lattice

Suppose G is a graph. Let u be a vertex of G . A vertex v is called an i -neighbor of u if d G ( u , v) = i . A 1-neighbor of u is simply called a neighbor of u . Let s and t be two nonnegative integers. Suppose f is an assignment of nonnegative integers to the vertices of G . If the following three conditions are satisﬁed, then f is called an ( s , t ) -relaxed L ( 2 , 1 ) -labeling of G : (1) for any two adjacent vertices u and v of G , f ( u ) (cid:2)= f (v) ; (2) for any vertex u of G , there are at most s neighbors of u receiving labels from { f ( u ) − 1 , f ( u ) + 1 } ; (3) for any vertex u of G , the number of 2-neighbors of u assigned the label f ( u ) is at most t . The minimum span of ( s , t ) - relaxed L ( 2 , 1 ) -labelings of G is called the ( s , t ) -relaxed L ( 2 , 1 ) -labeling number of G , denoted by λ s , t 2 , 1 ( G ) . It is clear that λ 0 , 0 2 , 1 ( G ) is the so called L ( 2 , 1 ) -labeling number of G . In this paper, the ( s , t ) -relaxed L ( 2 , 1 ) -labeling number of the triangular lattice is determined for each pair of two nonnegative integers s and t . And this provides a series of channel assignment schemes for the corresponding channel assignment problem on the triangular lattice.
On ( s , t ) -relaxed L ( 2 , 1 ) -labeling of graphs

We initiate the study of relaxed L ( 2 , 1 ) -labelings of graphs. Suppose G is a graph. Let u be a vertex of G . A vertex v is called an i -neighbor of u if d G ( u , v) = i . A 1-neighborof u issimplycalledaneighborof u . Let s and t betwononnegativeintegers. Suppose f isanassignmentofnonnegativeintegerstotheverticesof G . Ifthefollowing three conditions are satisﬁed, then f is called an ( s , t ) -relaxed L ( 2 , 1 ) -labeling of G : (1) for any two adjacent vertices u and v of G , f ( u ) (cid:2)= f (v) ; (2) for any vertex u of G , there are at most s neighbors of u receiving labels from { f ( u ) − 1 , f ( u ) + 1 } ; (3) for any vertex u of G , the number of 2-neighbors of u assigned the label f ( u ) is at most t . The minimum span of ( s , t ) -relaxed L ( 2 , 1 ) -labelings of G is called the ( s , t ) -relaxed L ( 2 , 1 ) -labeling number of G , denoted by λ s , t 2 , 1 ( G ) . It is clear that λ 0 , 0 2 , 1 ( G ) is the so called L ( 2 , 1 ) -labeling number of G . λ 1 , 0 2 , 1 ( G ) is simply written as (cid:2) λ( G ) . This paper discusses basic properties of ( s , t ) -relaxed L ( 2 , 1 ) -labeling numbers of graphs. For any two nonnegative integers s and t , the exact values of ( s , t ) -relaxed L ( 2 , 1 ) -labeling numbers of paths, cycles and complete graphs are determined. Tight upper and lower bounds for ( s , t
Optimal Dividends in the Dual Model with Diffusion

In the dual model, the surplus of a company is a Levy process with sample paths that are skip-free downwards. In this paper, the aggregate gains process is the sum of a shifted compound Poisson process and an independent Wiener process. By means of Laplace transforms, it is shown how the expectation of the discounted dividends until ruin can be calculated, if a barrier strategy is applied, and how the optimal dividend barrier can be determined. Conditions for optimality are discussed and several numerical illustrations are given. Furthermore, a family of models is analysed where the individual gain amount distribution is rescaled and compensated by a change of the Poisson parameter.
Follow-up of Young Stars Identified with BANYAN Σ: New Low-mass Members of Nearby Moving Groups

The characterization of moving groups offers a powerful means to identify large populations of young stars. In this paper, we present a sample of follow-up observations for 56 systems that have previously been proposed as members of young stellar associations through the application of the BANYAN Σ kinematic classification tool. Our measurements, which probe seven different associations, provide a sample of 39 stellar systems that either are confirmed or appear consistent with being young members of their respective associations. Nineteen of these are single M dwarfs. This sample expands our knowledge of Upper Centaurus Lupus, Coma Berenices, and AB Doradus Major to cooler temperatures and also significantly increases the known population of the Carina-Near association. The young systems present excellent targets for future planet searches and would also be valuable for studies of star formation and evolution. Additionally, we find two stellar systems that show indications of being rare instances of late-stage circumstellar accretion. Lastly, our follow-up measurements serve as a test of BANYAN Σ, finding an overall contamination rate that is consistent with previous findings (29% for systems with RV measurements, 37% without).
Technical efficiency analysis of maize farming in Wajak District, Malang Regency with data envelopment analysis approach

Technical efficiency is becoming essential indicators in estimating agriculture productivity, The aims of this research are to estimate the technical efficiency level and analysis factors affecting the technical efficiency level of maize farmer. The research was conducted in Wajak Sub-District of Malang Regency in East Java, Indonesia. Primary data was collected from 110 maize farmers and analyzed by data envelopment analysis and Tobit regression model. The result of this study claimed that farmers in the research location are technically inefficient because of the technical efficiency level less than one. Furthermore, the result of Tobit regression shows that the farmers’ education level has a significant and positive effect on technical efficiency level. However, the family dependency and farmer group participation have a significant and negative effect on technical efficiency level. This finding can be concluded that farmers need to minimize the input usage to increase the technical efficiency level.
Vibration-based structural health monitoring technique using statistical features for data stability assessment and damage localization

A statistical vibration-based damage identification algorithm to assess the stability of the measurement data, detect and locate damage in civil structures, where variability in response and modal parameters due to measurement noise and environmental influence is often inevitable, is presented in this paper. The algorithm utilizes the statistical correlation of the magnitudes of frequency response function (FRF) of target sensors relative to a reference sensor to assess the consistency of the data while the slopes of lines of fit are exploited for damage localization. Through numerical simulation and experimental investigation of a flexural structure using accelerometers and "point" strain gauges, and long gauge fiber Bragg gratings (FBG) sensors, the importance of the technique for civil SHM is established and presented in an easy-to-interpret graphical format for effective implementation of results. The proposed method using long-gauge FBG sensors is suitable for practical civil SHM with limited number of sensors and where variability in response and modal parameters due to measurement noise and environmental influence is often inevitable. Also, the ability to effectively manage and make sense of enormous amounts of data collected under continuous monitoring process for an effective diagnostic and/or prognostic system is an added advantage.
Condition assessment of transformers in wind farm based on modified one-dim residual neural network

The working environment of transformers in the wind farm is more complex than others, which brings the difference in condition assessment. Moreover, many condition assessment methods based on characteristics or machine learning have difficulty in recognition in cases of multiple transformers, conditions and measuring points. To assess conditions, this paper establishes a condition classification model of the transformer with a modified one-dim residual neural network and uses vibration signal, current and voltage as inputs. The built network mode has faster convergence speed and classification accuracy in transformer condition assessment and is more suitable for transformer condition assessment than the original one.
Shade sensitivity index of six brown-seeded soybean (Glycine max (L.) Merrill) genotypes based on seed weight

This study aims to find out the shade sensitivity indexes of six brown-seeded soybean genotypes based on the yield (seed weight). This study was carried out using the experimental methods with the experimental design of a split plot design. The main plot was the shade stress conditions (S) consisting of S0 = without shade stress and S1 = 65% shade stress (using black shading net house). The sub plot was the brown-seeded soybean genotypes (G) consisting of six lines: G1 = KH7b; G2 = KH7c; G3 = KH7d; G4 = KH9; G5 = KH14; and G6 = KH50b. The results of the study showed that: 1). The KH50b genotype was the most shade suscaptable genotype follewed by KH7d, KH14, and KH9 as indicated by the highest shade sensitivity index (SSI) and tolerance index (TOL). 2). The KH7b genotype was the most shade tolerance genotype followed by KH7c as indicated by the lowest shade sensitivity index (SSI) and tolerance index (TOL). KH7b and KH7c genotypes were the most stable genotypes as indicated by the highst yield stability index (YSI) and yield index (YI). The highest yield (seed weight) under normal (no stress) condition was KH50b genotype and under the shade stress was KH7b genotype.
RLS-based BeiDou Satellite High Precision Positioning for Power Device

The BeiDou-3 navigation satellite system (BDS-3) has been officially put into use, which will provide wider, more accurate, and smarter industrial applications. BDS-3 positioning has advantages of stability, economical reliability and most importantly, high positioning accuracy, which is widely used in power systems, covering power dispatching, energy management, data acquisition, and system monitoring. However, in the positioning process of BDS-3, positioning accuracy will be affected by spatial and temporal interference factors. This paper addresses the problem of poor positioning accuracy under the interference influence of BDS-3, and proposes a Recursive Least Squares (RLS)-based adaptive high-precision positioning scheme to effectively reduce the influence of interference factors.
Thermal Analysis and Test of Axial Flux Permanent Magnet Synchronous Motor Performances

The axial flux permanent-magnet synchronous motor with amorphous alloy stators has the advantages of high power density, high efficiency, large starting torque. But the PMSM has poor performance in heat resistant and radiation. And the electromagnetic loss has a significant impact on in-wheel motor’s heat generation. To demonstrate the influence of electromagnetic loss on winding coils of the PMSM, the mathematical model of the thermal transformation was founded to illustrate the progress of temperature rising. The mathematical model and experimental test were verified mutually. The experimental prototype was manufactured and tested, including the output power model and braking energy recovery model. And the experimental prototype performed working in low rotation speed mode and middle rotation speed mode separately, when the revolving speed increased by 50% the thermal of winding raise approximately 23.5%. Further, the analytic formulas and experimental results consistent with each other approximately, in which the mathematical analysis method was verified by test value.
Research on Transformer Oil Level Monitoring System Based on Inspection Robot

Because the traditional oil level gauge transformer relies on manual regular patrol detection, it is not easy to know the state change of the oil level in real time. In recent years, the rapid development of AR/VR technology, the positioning, and the construction of maps of robots have also received widespread attention, and the oil level inspection task has gradually evolved in the direction of intelligent machine inspection. Based on this background, this paper studies the Cartographer algorithm, according to the mapping results for path planning, to achieve robot autonomous navigation of the designated location. After arriving at the destination, the user obtains the oil level by the depth camera, and uses the YOLOv4 to design an intelligent detection algorithm for oil level detection, using neural networks to learn the oil level state in various weather, and train a dedicated model. Through experimental verification, the inspection robot can complete the construction of the map and realize autonomous path navigation according to the target point, and the oil level detection system based on the YOLOv4 algorithm can achieve an accuracy of more than 90% for the recognition of oil level information, which has good applicability.
Stability and Hopf bifurcation of coexistence steady-states to an SKT model in spatially heterogeneous environment

This paper is concerned with the following Lotka-Volterra cross-diffusion system ut = Δ[(1+kρ(x) v)u] +u(a-u-c(x)v) in Ω Χ (0, ∞), τvt = Δv +v(b+d(x)u-v) in Ω Χ (0, ∞) in a bounded domain Ω ⊂ RN with Neumann boundary conditions δvu = δvv = 0 on δΩ. In the previous paper [18], the author has proved that the set of positive stationary solutions forms a fishhook shaped branch Γ under a segregation of $\rho (x)$ and $d(x)$. In the present paper, we give some criteria on the stability of solutions on Γ. We prove that the stability of solutions changes only at every turning point of Γ if τ is large enough. In a different case that $c(x)\ >\ 0$ is large enough, we find a parameter range such that multiple Hopf bifurcation points appear on Γ.
Time-Dependent X-ray Bragg Diffraction

The theory of time-dependent X-ray Bragg diffraction by crystals is developed on the basis of the Green-function (point-source) formalism. A general case of incident radiation partially coherent in time and space is considered. The time-delay effect of the diffracted radiation is described when the ultrashort time duration incident pulse strikes the crystal surface. The problem in question is closely connected with the effect of time delay in the resonance scattering of synchrotron radiation by nuclei in a crystal. It is found that, for the case where the incident wave is plane (or is an incoherent superposition of plane waves) and the time-dependent pulse is a pseudo 6 function in time, the instantaneous crystal reflectivity is a smooth temporal function and tends to the value corresponding to the integrated reflectivity calculated by means of the conventional dynamical-kinematical X-ray diffraction theory. If the incident X-ray pulse profile is a pseudo 6 function in both time and space, the temporal crystal response has the same functional dependence as the spatial distribution of the diffracted intensity under the condition of conventional Bragg diffraction of the X-ray beam with lateral width < t o c, where the time delay t o is equal to Λ/2πc and (μ o c) -1 in the cases of dynamical and kinematical X-ray scattering within a crystal, respectively (Λ is the X-ray extinction length, μ o is the linear absorption coefficient and c is the velocity of light in vacuum).
Blood coagulation using High Intensity Focused Ultrasound (HIFU)

High Intensity Focused Ultrasound (HIFU) technology provides a feasible method of achieving thermal coagulation during surgical procedures. One of the potential clinical benefits of HIFU can induce immediate hemostasis without suturing. The objective of this study was to investigate the efficiency of a HIFU system for blood coagulation on severe vascular injury. ngHIFU treatment was implemented immediately after bleeding in artery. The ultrasound probe was made of piezoelectric material, generating a central frequency of 2.0 MHz as well as an ellipsoidal focal spot of 2 mm in lateral dimension and 10 mm in axial dimension. Acoustic coagulation was employed on a perfused chicken artery model in vitro. A surgical incision (1 to 2 mm long) was made with a scapel on the arterial wall, and heparinized autologous blood was made to leak out from the incision with a syringe pump. A total of 5 femoral artery incisions was treated with the HIFU beam. The intensity of 4500 W/cm2 at the focus was applied for all treatments. Complete hemostasis was achieved in all treatments, along with the treatment times of 25 to 50 seconds. The estimated intraoperative blood loss was from 2 to 5 mL. The proposed HIFU system may provide an effective method for immediate blood coagulation for arteries and veins in clinical applications.
Continuous expected utility for arbitrary state spaces

Subjective expected utility maximization with continuous utility is characterized, extending the result of Wakker (1984, Journal of Mathematical Psychology) to infinite state spaces. In Savage (1954, The Foundations of Statistics) the main restriction, P6, requires structure for the state space, e.g. this must be infinite. The main restriction of this paper, requiring continuity of the utility function, may be more natural in economic contexts, since it is based on topological structure of the consequence space, structure that usually is present in economic contexts anyhow. Replacing the state interpretation by a time interpretation yields a characterization for dynamic contexts.