Miracle-dz/UniFAR-FTUs huggingface dataset:
The design and algorithm mapping of a heterogeneous multi-core processor for SDR

In this paper, we present a new fully programmable heterogeneous multi-core processor architecture for SDR (software defined radio). To meet the computation properties of different algorithms, our solution contains three types of processor cores: two SIMD (Single Instruction Multiple Data) cores, four general purpose DSP cores and an embedded controller core. In order to verify the efficiency of our processor architecture, we implement baseband algorithms of W-CDMA (Wideband Code Division Multiple Access) and WiMax (Worldwide Interoperability for Microwave Access), and mapped them onto the proposed architecture. The result exhibits that this solution can support W-CDMA and WiMAX at about 25.7 mm2 and 0.47 W at 70 nm technology.
On the dispersive versus arrhenius temperature activation of nbti time evolution in plasma nitrided gate oxides: measurements, theory, and implications

Negative bias temperature instability (NBTI) is studied in p-MOSFETs having decoupled plasma nitrided (DPN) gate oxides (EOT range of 12 Aring through 22Aring). Threshold voltage shift (DeltaVT) is shown to be primarily due to interface trap generation (DeltaNIT) and significant hole trapping (DeltaNOT) has not been observed. DeltaVT follows power-law time (t) dependence and Arrhenius temperature (T) activation
The N-terminal Peptide of the Kaposi's Sarcoma-associated Herpesvirus (KSHV)-cyclin Determines Substrate Specificity*

Cyclin-dependent kinases (Cdks) are activated by cyclin binding and phosphorylation by the Cdk-activating kinase (CAK). Activation of Cdk6 by the D-type cyclins requires phosphorylation of Cdk6 by CAK on threonine 177. In contrast, Cdk6 is activated by the Kaposi's sarcoma-associated herpesvirus (KSHV)-cyclin in the absence and presence of CAK phosphorylation. The activity of Cdk6·KSHV-cyclin complexes was investigated here by analyzing mutants of the KSHV-cyclin and Cdk6 in vitro as well as in U2OS cells. Deletion of the N terminus of the KSHV-cyclin affects the substrate specificity indicating that the N terminus is required for phosphorylation of histone H1 but not for other substrates. Mutation of residues in the region 180–200 of the KSHV-cyclin decreases the binding affinity to Cdk6 in U2OS cells but increases the activity of Cdk6·KSHV-cyclin complexes in vitro indicating that low affinity binding of cyclins to the Cdk subunit might favor increased on- or off-rates of Cdk substrates. Expression of high levels of p16INK4a in cells leads to the formation of a heterotrimeric complex composed of Cdk6, KSHV-cyclin, and p16INK4a. Some of the Cdk6·KSHV-cyclin·p16 complexes were found to be active indicating that there might be different modes of p16 binding to Cdk6·cyclin complexes.
3D Magnetic Field Modelling and Force Computation of a Permanent Magnet Linear Actuator

Three-dimensional finite element method has been used for modelling of the magnetic field and computation of the electromagnetic force of recently developed permanent magnet linear actuator. The actuator is subject to specific requirements – having four stable positions without supply and maintaining minimum static force during the whole working stroke. The actuator consists of several cores with coils placed on a common yoke and a moving permanent magnet. It is intended for needle driving in a knitting machine. Influence of different factors on the static force characteristic is estimated.
Stiffness, damping and creep properties of a poly foam including the effects of temperature and humidity

Experiments have been made to establish the physical properties of a flexible polyurethane foam plastic used in the construction of aeroelastic models for use in low-speed wind tunnels. Simple static and dynamic bending tests were made on a composite cantilever of plastic foam and a light alloy bar. It is shown that dynamic stiffness and damping capacity measurements must take account of temperature and absolute humidity, and that the dynamic stiffness is almost double tbe static value. Other phenomena such as creep and the effect of "working" are discussed.
Pancreatic cancer.

Pancreatic cancer (PC) is the 10th most common cancer type and the fourth leading cause of cancer-related deaths. The vast majority of PCs are pancreatic adenocarcinomas. Diagnosis of small tumors at an early stage or dysplastic premalignant lesions that can be surgically resected offers patients the best chances for survival and can increase 5-year survival rates from approximately 5% to 20%–30%, or even higher, at specialized treatment centers. The early stages of PC are usually asymptomatic, and the aggressive nature of this disease, in combination with our limited capability for early detection, contribute to the very low percentage of patients (approximately 20%) diagnosed with resectable disease. Large numbers of early diagnoses are due to incidental findings during abdominal imaging procedures.
Defect-oriented testing and diagnosis of digital microfluidics-based biochips

Microfluidics-based biochips are soon expected to revolutionize biosensing, clinical diagnostics and drug discovery. Robust off-line and on-line test techniques are required to ensure system dependability as these biochips are deployed for safety-critical applications. Due to the underlying mixed-technology and mixed-energy domains, biochips exhibit unique failure mechanisms and defects. We first relate some realistic defects to fault models and observable errors. We next set up an experiment to evaluate the manifestations of electrode-short faults. Motivated by the experimental results, we present a testing and diagnosis methodology to detect catastrophic faults and locate faulty regions. The proposed method is evaluated using a biochip performing real-life multiplexed bioassays
Hypothesized Eye Movements of Neurolinguistic Programming: A Statistical Artifact

Neurolinguistic programming's hypothesized eye-movements were measured independently from videotapes of 30 subjects, aged 15 to 76 yr. , who were asked to recall visual pictures, recorded audio sounds, and textural objects. χ2 indicated that subjects' responses were significantly different from those predicted. When χ2 comparisons were weighted by number of eye positions assigned to each modality (3 visual, 3 auditory, 1 kinesthetic), subjects' responses did not differ significantly from the expected pattern. These data indicate that the eye-movement hypothesis may represent randomly occurring rather than sensory-modality-related positions.
OCR++: A Robust Framework For Information Extraction from Scholarly Articles

This paper proposes OCR++, an open-source framework designed for a variety of information extraction tasks from scholarly articles including metadata (title, author names, affiliation and e-mail), structure (section headings and body text, table and figure headings, URLs and footnotes) and bibliography (citation instances and references). We analyze a diverse set of scientific articles written in English to understand generic writing patterns and formulate rules to develop this hybrid framework. Extensive evaluations show that the proposed framework outperforms the existing state-of-the-art tools by a large margin in structural information extraction along with improved performance in metadata and bibliography extraction tasks, both in terms of accuracy (around 50% improvement) and processing time (around 52% improvement). A user experience study conducted with the help of 30 researchers reveals that the researchers found this system to be very helpful. As an additional objective, we discuss two novel use cases including automatically extracting links to public datasets from the proceedings, which would further accelerate the advancement in digital libraries. The result of the framework can be exported as a whole into structured TEI-encoded documents. Our framework is accessible online at http://www.cnergres. iitkgp.ac. in/OCR++/home/.
Lung Function and Respiratory Symptoms at 11 Years in Children Born Extremely Preterm: The Epicure Study

J Fawke, S Lum, J Kirkby. Am J Respir Crit Care Med. 2010;182(2):237–245 More extremely preterm (EP) infants (≤25 weeks' gestational age) are surviving. What becomes of these children in terms of lung function? This was a national cohort study that involved all infants born at ≤25 completed weeks' gestation in the United Kingdom and Ireland between March and December 1995 ( N = 182). At the age of 11 years, parents completed a questionnaire …
Concurrent discrimination learning of monkeys after hippocampal, entorhinal, or fornix lesions

Ablations of anterior inferotemporal cortex in monkeys are known to impair learning when discriminations between members of several pairs of objects are taught concurrently. This deficit has been attributed to a loss of visual mnemonic functions. But ablations of hippocampus have also been shown to impair retention, and this impairment transcends the visual modality. Therefore, in the first of two experiments, we compared the behavioral effects of inferotemporal cortical lesions with those of either hippocampus, entorhinal area, or fornix, using a visual concurrent discrimination task. Monkeys with either hippocampal or entorhinal ablations were impaired, while those with fornix sections were not. However, ablations of hippocampus included inadvertent damage of the inferotemporal cortex. Therefore, in the second experiment, behavioral effects of inferotemporal lesions were compared with those of hippocampus (without additional inferotemporal damage) on the concurrent task in both visual and tactual modalities. In the visual mode, monkeys with hippocampal removals were as impaired as those with inferotemporal ablations. In the tactual mode, however, hippocampal, but no inferotemporal, ablations were followed by a deficit. Our results, taken together with other existing evidence, emphasize the role of the hippocampus in mediating associative learning in more than one modality. These results, obtained with non-human primates, are in line with clinical findings.
Resting-State Brain Abnormalities in Chronic Subjective Tinnitus: A Meta-Analysis

Purpose: The neural mechanisms that give rise to the phantom sound of tinnitus have not been fully elucidated. Neuroimaging studies have revealed abnormalities in resting-state activity that could represent the neural signature of tinnitus, but there is considerable heterogeneity in the data. To address this issue, we conducted a meta-analysis of published neuroimaging studies aimed at identifying a common core of resting-state brain abnormalities in tinnitus patients. Methods: A systematic search was conducted for whole-brain resting-state neuroimaging studies with SPECT, PET and functional MRI that compared chronic tinnitus patients with healthy controls. The authors searched PubMed, Science Direct, Web of Knowledge and Embase databases for neuroimaging studies on tinnitus published up to September 2016. From each study, coordinates were extracted from clusters with significant differences between tinnitus subjects and controls. Meta-analysis was performed using the activation likelihood estimation (ALE) method. Results: Data were included from nine resting-state neuroimaging studies that reported a total of 51 distinct foci. The meta-analysis identified consistent regions of increased resting-state brain activity in tinnitus patients relative to controls that included, bilaterally, the insula, middle temporal gyrus (MTG), inferior frontal gyrus (IFG), parahippocampal gyrus, cerebellum posterior lobe and right superior frontal gyrus. Moreover, decreased brain activity was only observed in the left cuneus and right thalamus. Conclusions: The current meta-analysis is, to our knowledge, the first to demonstrate a characteristic pattern of resting-state brain abnormalities that may serve as neuroimaging markers and contribute to the understanding of neuropathophysiological mechanisms for chronic tinnitus.
The relationship between the oral and pharyngeal phases of swallowing

OBJECTIVE: This study was designed to investigate a possible relationship between the duration of the oral and pharyngeal phases of swallowing. INTRODUCTION: The oral and pharyngeal phases of swallowing are independent from each other but may be related. METHODS: We used videofluoroscopy to evaluate 30 healthy volunteers between 29 and 77 years of age who swallowed 5- and 10-ml liquid and paste boluses in duplicate. The duration of the oral phase, pharyngeal transit, and pharyngeal clearance were measured. RESULTS: There were no differences in oral or pharyngeal transit times between the liquid and paste boluses or between the volumes of 5 and 10 ml (p>0.40). The pharyngeal clearance time for the paste bolus (0.48±0.27 s) was longer than for the liquid bolus (0.38±0.11 s, p = 0.03) with no difference between the volumes of 5 and 10 ml. There was no significant correlation between the oral transit time and the duration of pharyngeal transit for the liquid (5 ml, Spearman's coefficient ρ: −0.14; 10 ml, ρ: 0.18) or the paste (5 ml, ρ: 0.08; 10 ml, ρ: 0.10). The correlation between the oral transit time and the pharyngeal clearance time was not significant for the liquid bolus (5 ml, ρ: 0.31; 10 ml, ρ: 0.18), but it was significant for both the 5 ml (ρ: 0.71) and 10 ml (ρ: 0.64) paste boluses. DISCUSSION: The relationship between the oral and pharyngeal phases of swallowing can be affected by bolus consistency. CONCLUSION: There is a correlation between the duration of oral transit and the duration of pharyngeal clearance during the swallowing of paste boluses.
Experiment and Analysis on the Mechanical Behaviour of PC Simply-Supported Slabs Subjected to Fire

Experiments on the fire resistance of 9 unbonded and 1 bonded prestressed concrete (PC) simply-supported slabs are completed. Calculation formula of the stress in the unbonded prestressing steel wires in PC simply-supported slabs subjected to fire is obtained based on the experimental results. Dividing the section of the slab into strips along its depth according to the distribution of temperature field, on the basis of invariable width of the slab in the surface exposed to fire, the transformed section of the slab subjected to fire can be obtained by multiplying the width of each strip by the elasticity modulus ratio of the strip concerned and the extreme strip in the surface exposed to fire. The stress in concrete and curvature in the researched section caused by load can be obtained based on equilibrium equations of force and moment on transformed section. Then, the methods for calculating concrete thermal strain, transient strain and creep at elevated temperature were introduced, and total strain of a point in the concerned section and total curvature caused by load and temperature can be calculated considering time-dependent effect. After the total curvature of the mid-span section was calculated, the actual stiffness of the critical section in the mid-span can be determined, moreover, the mid-span deflection of the PC slab can be calculated by the virtual displacement principle. The practical calculation formulas for the mid-span deflection of PC simply-supported slabs subjected to fire is presented considering the influences of the deflection of slabs at the ambient temperature, ratio of concrete cover to depth of slabs, load level, combined reinforcement index and span.
Business intelligence for Business Intelligence: A case study at STMicroelectronics

Business Intelligence (BI) aims to support business users to make decisions by providing methods and tools to easily access and manage their information. Even if many organizations have employed BI applications, not all of them have been successful. Therefore, it is important to ensure that they fit business and users' needs in terms of information, knowledge and decision. In this paper, a proposal to apply BI for BI is elaborated. Analysing a BI system based on BI techniques is our main contribution and it is the core of our proposal. While involving users, our proposal aims to identify BI indicators and dimensions and to propose a system architecture allowing to analyse the current BI environment and make decisions about its use. A case study at STMicroelectronics has been conducted since it uses a BI system for making decisions.
Dysregulation of DDAH : A Novel Mechanism of Endothelial Dysfunction

Asymmetric dimethylarginine (ADMA) is an endogenous and competitive inhibitor of nitric oxide synthase. Plasma levels of this inhibitor are elevated in patients with atherosclerosis and in those with risk factors for atherosclerosis. In these patients, plasma ADMA levels are correlated with the severity of endothelial dysfunction and atherosclerosis. By inhibiting the production of nitric oxide, ADMA may impair blood flow, accelerate atherogenesis, and interfere with angiogenesis. ADMA may be a novel risk factor for vascular disease. (Arterioscler Thromb Vasc Biol. 2000;20:2032-2037.)
Mood Disorders And Their Pharmacological Treatment During Pregnancy: Is the Future Child Affected?

Nearly half the US population will meet criteria for a neuropsychiatric disorder at some point in their lives, and 1 in 17 has a seriously debilitating illness. Although not all affected adults had an identified disorder as a child, increasingly these psychopathologies are conceptualized as the late-stage culmination of aberrant developmental processes shaped by a complex interplay of genes and experience, including experiences in utero. Decades of studies with pregnant animals demonstrate that stress-elicited perturbations in maternal biology affect offspring neurodevelopment. Studies of stress in pregnant women largely mirror these findings. Pregnant women with anxiety and/or depression experience greater life stress, and illness-related alterations in their neurobiology, with a potential to impact fetal neurobehavioral development via associated changes in the intrauterine environment and/or pharmacologic interventions. This article critically reviews findings on child development (including fetal neurobehavior) related to maternal depression, anxiety, and pharmacological treatments, primarily selective serotonin reuptake inhibitors (SSRIs). The hypothesis under review is that, in addition to genetics and characteristics of the postnatal environment, the familial transmission of risk for neuropsychiatric disorders involves a “third path”—prenatal exposure to psychiatric illness and its treatment.
Characteristics of Enzymatic Hydrolysis of the Wheat Gluten Proteins Treated by Ultrasound Wave

Effects of sonication at 150W and 300W power output on hydrolysis of wheat gluten using two proteinases (Protamex and papain) were evaluated in the present study. Sonication resulted in the increase in amounts of free sulphydryl (SH) of wheat gluten. Significant (P < 0.05) increase in SH contents at 300W power output was found compared with the control and those samples sonicated at 150W power output. Degree of hydrolysis (DH) and protein recovery (PR) of the wheat gluten hydrolysates increased with sonication time and power output. Significant (P < 0.05) increase in DH and PR of the wheat gluten hydrolysate from the sample sonicated by 300W power output was found compared to those sonicated by 150W output. Sonication caused the decrease in the relative percent of the large peptide fractions and increase in the relative percent of the small peptide fractions in the hydrolysates compared to the control. Structure change in insoluble wheat gluten proteins was the principal reason of improvement in their characteristics of enzymatic hydrolysis.
Limited-lifetime shared-access in mobile systems

In this paper, we propose a simple access protocol to shared information in a mobile environment. The objective of the proposed scheme is to allow a specified set of users access toshared information and protect the confidentiality of the information from users outside this set. The set of users may be updated from time to time. In particular, the duration during which a user is allowed access to the shared information may be restricted. Furthermore, the information itself has limited lifetime and the confidentiality of the information has to be preserved during this lifetime only. The proposed access protocol is in particular suited to the mobile environment, because of the loose binding of the communicating entities.
International Union of Pharmacology. XXVIII. Proteinase-Activated Receptors

Proteinase-activated receptors (PARs) represent a unique subclass of G-protein-coupled receptors of which four family members have now been cloned from a number of species. The novel mechanism of receptor activation involves the proteolytic unmasking of a cryptic N-terminal receptor sequence that, remaining tethered, binds to and triggers receptor function. In addition, short (five to six amino acids) synthetic peptides, based on the proteolytically revealed motif, can activate PARs without the unmasking of the tethered ligand. This article summarizes the experiments leading to the pharmacological characterization and cloning of the four PAR family members and provides a rationale for their designation by the acronym “PAR”. The ability to distinguish among the PARs pharmacologically 1) with selective proteinase activators, 2) with receptor-selective peptide agonists, and 3) with peptide and nonpeptide antagonists is discussed, as are the molecular mechanisms of receptor activation and desensitization/internalization. Finally, the potential physiological roles of the PARs, which are widely distributed in many organs in the settings of tissue injury, repair, and remodeling, including embryogenesis and oncogenesis are discussed, and the newly appreciated roles of proteinases as signaling molecules that can act as either functional agonists or antagonists are highlighted.
Prevalence of Internet addiction and risk of developing addiction as exemplified by a group of Polish adolescents from urban and rural areas.

OBJECTIVE The objective of the study was to determine the prevalence of Internet addiction and the risk of developing this addiction in Polish adolescents attending junior high schools and high school in Lublin Province, to indicate the differences regarding the intensity of Internet addiction symptoms, and the types of online activity of adolescents residing in urban and rural areas. MATERIAL AND METHODS The examined group comprised 1,860 participants (1,320 girls and 540 boys) with an average age of 17 years. 760 students lived in urban areas and 1,100 lived in rural areas. The following were used in the study: the Socio-demographic Questionnaire designed by the authors, the Internet Addiction Questionnaire designed by Potembska, the Internet Addiction Test by Young and the Internet Addiction Questionnaire (Kwestionariusz do Badania Uzależnienia od Internetu - KBUI) designed by Pawłowska and Potembska. RESULTS The adolescents living in urban areas showed a significantly greater intensity of Internet and computer addiction symptoms measured by the KBUI Questionnaire, compared to those living in rural areas. CONCLUSIONS The Internet addiction criteria were fulfilled by 0.45% of adolescents living in urban areas and 2.9% of those living in rural areas, whereas 35.55% of urban dwelling students and 30.18% of students living in rural areas showed a risk of developing this addiction. More adolescents living in urban areas, compared to those living in rural areas, use Internet pornography, play computer games, disclose their personal data to unknown individuals encountered on the Internet, use Instant Messaging (IM) services, electronic mail and Facebook social networking service. Compared to their peers from urban areas, significantly more adolescents from rural areas use 'Nasza Klasa' (Our Classmates) online social networking service.