Miracle-dz/UniFAR-FTUs huggingface dataset:
ELECTRON ACCELERATION BY MULTI-ISLAND COALESCENCE

Energetic electrons of up to tens of MeV are created during explosive phenomena in the solar corona. While many theoretical models consider magnetic reconnection as a possible way of generating energetic electrons, the precise roles of magnetic reconnection during acceleration and heating of electrons still remain unclear. Here, we show from two-dimensional particle-in-cell simulations that coalescence of magnetic islands that naturally form as a consequence of tearing mode instability and associated magnetic reconnection leads to efficient energization of electrons. The key process is the secondary magnetic reconnection at the merging points, or the “anti-reconnection,” which is, in a sense, driven by the converging outflows from the initial magnetic reconnection regions. By following the trajectories of the most energetic electrons, we found a variety of different acceleration mechanisms but the energization at the anti-reconnection is found to be the most important process. We discuss possible applications to the energetic electrons observed in the solar flares. We anticipate our results to be a starting point for more sophisticated models of particle acceleration during the explosive energy release phenomena.
The Prevalence of Prison-based Physical and Sexual Victimization in Males and Females: A Systematic Review and Meta-Analysis

This systematic review investigated the prevalence of prison-based interpersonal harm by type of victimization (physical and sexual) and sex, along with the heterogeneity among studies using meta-regression. Using Preferred Reporting Items for Systematic Reviews and the Meta-Analysis guidelines, 24 articles met the selection criteria. Study quality was assessed using the Joana Briggs Institute (20.8% deemed low quality, 33.3% moderate, and 45.9% high). Searches were conducted in Criminal Justice Abstracts, PsycINFO, PubMed, and Web of Science. The 24 articles comprised 36 separate samples inclusive of 23,967 incarcerated individuals. The random-effects pooled prevalence estimate of prison-based physical victimization was 18.8%, with slightly higher rates for females (20.3%) than males (18.1%). For sexual victimization, the pooled prevalence estimate was 12.4%, with higher rates among females (15.3%) than males (9.7%). For females, younger individuals reported higher rates of physical and sexual victimization and studies using smaller samples had higher rates of physical victimization. Rates of physical and sexual victimization for men were higher if perpetrators included residents and staff, the recall period was since admission, data was collected using self-administered surveys, and in low-quality studies (sexual victimization only). Rates of prison-based interpersonal harm, while high, varied significantly by type of victimization, sex, and study methodology. High heterogeneity will be reduced only if future studies adhere to best methodological practices in defining and collecting data on interpersonal harm and consistently test risk and prevention factors instrumental to prevention efforts. Study limitations include the exclusion of unpublished and non-English-language studies, small sample sizes for female studies, and methodological “noise” within the literature that reduce predictive precision.
Deep imaging of Fanaroff–Riley Class I radio galaxies with lobes

We present deep, high-resolution imaging of the nearby Fanaroff–Riley Class I (FR I) radio galaxies NGC 193, B2 0206+35, B2 0755+37 and M84 at frequencies of 4.9 and 1.4 GHz using new and archival multiconfiguration observations from the Very Large Array. In addition, we describe lower resolution observations of B2 0326+39 and a re-analysis of our published images of 3C 296. All of these radio galaxies show twin jets and well-defined lobes or bridges of emission, and we examine the common properties of this class of source. We show detailed images of total intensity, brightness gradient, spectral index, degree of polarization and projected magnetic-field direction. The jet bases are very similar to those in tailed twin-jet sources and show the characteristics of decelerating, relativistic flows. Except on one side of M84, we find that the jets can be traced as least as far as the ends of the lobes, where they often form structures which we call ‘caps’ with sharp outer brightness gradients. Continuing, but less well collimated, flows back into the lobes from the caps can often be identified by their relatively flat spectral indices. The lobes in these radio galaxies are similar in morphology, spectral-index distribution and magnetic-field structure to those in more powerful (FR II) sources, but they lack hotspots or other evidence for strong shocks at the ends of the jets. M84 may be an intermediate case between lobed and tailed sources, in which one jet does not reach the end of its lobe, but disrupts to form a ‘bubble’.
Global symmetry is unnecessary for fast quantum search

Grover's quantum search algorithm can be formulated as a quantum particle randomly walking on the (highly symmetric) complete graph, with one vertex marked by a nonzero potential. From an initial equal superposition, the state evolves in a two-dimensional subspace. Strongly regular graphs have a local symmetry that ensures that the state evolves in a three-dimensional subspace but most have no global symmetry. Using degenerate perturbation theory, we show that quantum random walk search on known families of strongly regular graphs, nevertheless, achieves the full quantum speed-up of Theta(root N), disproving the intuition that fast quantum search requires global symmetry.
Effect of low-damage inductively coupled plasma on shallow nitrogen-vacancy centers in diamond

Near-surface nitrogen-vacancy (NV) centers in diamond have been successfully employed as atomic-sized magnetic field sensors for external spins over the last years. A key challenge is still to develop a method to bring NV centers at nanometer proximity to the diamond surface while preserving their optical and spin properties. To that aim we present a method of controlled diamond etching with nanometric precision using an oxygen inductively coupled plasma process. Importantly, no traces of plasma-induced damages to the etched surface could be detected by X-ray photoelectron spectroscopy and confocal photoluminescence microscopy techniques. In addition, by profiling the depth of NV centers created by 5.0 keV of nitrogen implantation energy, no plasma-induced quenching in their fluorescence could be observed. Moreover, the developed etching process allowed even the channeling tail in their depth distribution to be resolved. Furthermore, treating a 12C isotopically purified diamond revealed a threefold increa.
THE STRUCTURE AND LINEAR POLARIZATION OF THE KILOPARSEC-SCALE JET OF THE QUASAR 3C 345

Deep Very Large Array imaging of the quasar 3C 345 at 4.86 and 8.44 GHz has been used to study the structure and linear polarization of its radio jet on scales ranging from 2 to 30 kpc. There is a 7–8 Jy unresolved core with spectral index α ≃ −0.24 (Iν∝να). The jet (typical intensity 15 mJy beam−1) consists of a 2. ″5 straight section containing two knots, and two additional non-co-linear knots at the end. The jet's total projected length is about 27 kpc. The spectral index of the jet varies over −1.1 ≲ α ≲ −0.5. The jet diverges with a semi-opening angle of about 9°, and is nearly constant in integrated brightness over its length. A faint feature northeast of the core does not appear to be a true counter-jet, but rather an extended lobe of this FR-II radio source seen in projection. The absence of a counter-jet is sufficient to place modest constraints on the speed of the jet on these scales, requiring β ≳ 0.5. Despite the indication of jet precession in the total intensity structure, the polarization images suggest instead a jet re-directed at least twice by collisions with the external medium. Surprisingly, the electric vector position angles in the main body of the jet are neither longitudinal nor transverse, but make an angle of about 55° with the jet axis in the middle while along the edges the vectors are transverse, suggesting a helical magnetic field. There is no significant Faraday rotation in the source, so that is not the cause of the twist. The fractional polarization in the jet averages 25% and is higher at the edges. In a companion paper, Roberts & Wardle show that differential Doppler boosting in a diverging relativistic velocity field can explain the electric vector pattern in the jet.
Effect of Androgen–Androgen Receptor Directed Therapy on COVID-19 Outcome in Prostate Cancer Patients

Abstract TMPRSS2 is utilized by SARS-CoV-2 for cellular entry. Androgen-Androgen receptor directed therapy (A/ARDT) downregulates expression of TMPRSS2. We hypothesized A/ARDT might protect prostate cancer (PCa) patients from poor COVID-19 outcome. A retrospective analysis of PCa patients with COVID-19 infection was performed. 146 PCa cases were identified, 17% were on A/ARDT. Hospitalization rates were same 52% (OR = 0.99, 0.41–2.24). Mean hospitalization was 9.2 (Range: 1–25) and 14.9 (Range: 2–47) days in A/ARDT and non-A/ARDT groups, respectively. While definitive conclusions cannot be made regarding outcome differences between groups due to lack of statistical significance, these data generate hypothesis that A/ARDT might shorten hospitalization stay.
On barrier and modified barrier multigrid methods for 3d topology optimization

One of the challenges encountered in optimization of mechanical structures, in particular in what is known as topology optimization, is the size of the problems, which can easily involve millions of variables. A basic example is the minimum compliance formulation of the variable thickness sheet (VTS) problem, which is equivalent to a convex problem. We propose to solve the VTS problem by the Penalty-Barrier Multiplier (PBM) method, introduced by R. \ Polyak and later studied by Ben-Tal and Zibulevsky and others. The most computationally expensive part of the algorithm is the solution of linear systems arising from the Newton method used to minimize a generalized augmented Lagrangian. We use a special structure of the Hessian of this Lagrangian to reduce the size of the linear system and to convert it to a form suitable for a standard multigrid method. This converted system is solved approximately by a multigrid preconditioned MINRES method. The proposed PBM algorithm is compared with the optimality criteria (OC) method and an interior point (IP) method, both using a similar iterative solver setup. We apply all three methods to different loading scenarios. In our experiments, the PBM method clearly outperforms the other methods in terms of computation time required to achieve a certain degree of accuracy.
A novel strategy against hepatitis B virus: Glycyrrhetnic acid conjugated multi-component synergistic nano-drug delivery system for targeted therapy

It is well known that Glycyrrhetnic acid (GA) has significant liver-targeting and anti-inflammatory effects. Syringopicroside (SYR) and Hydroxytyrosol (HT), the active components of the Chinese herb Syringa oblata Lindl, have earned great reputation for their potential in preventing or treating viral hepatitis type B. Therefore, we loaded SYR and HT into GA-conjugated PEG-PLGA, so that they could target the liver in additional to exerting their own pharmacological effects in a synergistic. However, the in vivo targeting and the low bioavailability of SYR and HT pose a huge challenge. Therefore, we synthesized GA-conjugated multi-component nano-drug delivery system (SH-GPP). SH-GPP had a regular spherical shape with a uniform size distribution of 110.5 ± 3.18 nm. We further evaluated the effects of SH-GPP in vitro and in vivo. In the in vivo experiment, we evaluated the following parameters: the serum ALT and AST values; liver tissue homogenate MDA and SOD; HE staining of the pathological liver sections; and the liver coefficient. In the in vitro studies, the following parameters were evaluated: cellular uptake of SH-GPP; wound healing/scratch assay; cellular apoptosis; cell cycle; HBsAg; and HBeAg content. SH-GPP had better anti-hepatitis B effect than Syringopicroside and hydroxytyrosol (SH) and NPP alone. The targeting ability of GA enabled HT and SYR in GPP to reach the liver accurately, and played a synergistic role to maximize their therapeutic effects. This study provides a novel strategy against hepatitis B virus, and also provides a feasible scheme for improving the low bioavailability of the active components of traditional Chinese medicine.
MIGRATION THEN ASSEMBLY: FORMATION OF NEPTUNE-MASS PLANETS INSIDE 1 AU

We demonstrate that the observed distribution of “hot Neptune”/“super-Earth” systems is well reproduced by a model in which planet assembly occurs in situ, with no significant migration post-assembly. This is achieved only if the amount of mass in rocky material is ∼50–100 M⊕ interior to 1 AU. Such a reservoir of material implies that significant radial migration of solid material takes place, and that it occurs before the stage of final planet assembly. The model not only reproduces the general distribution of mass versus period but also the detailed statistics of multiple planet systems in the sample. We furthermore demonstrate that cores of this size are also likely to meet the criterion to gravitationally capture gas from the nebula, although accretion is rapidly limited by the opening of gaps in the gas disk. If the mass growth is limited by this tidal truncation, then the scenario sketched here naturally produces Neptune-mass objects with substantial components of both rock and gas, as is observed. The quantitative expectations of this scenario are that most planets in the “hot Neptune/super-Earth” class inhabit multiple-planet systems, with characteristic orbital spacings. The model also provides a natural division into gas-rich (hot Neptune) and gas-poor (super-Earth) classes at fixed period. The dividing mass ranges from ∼3 M⊕ at 10 day orbital periods to ∼10 M⊕ at 100 day orbital periods. For orbital periods <10 days, the division is less clear because a gas atmosphere may be significantly eroded by stellar radiation.
Post-concussion symptoms 1-year after traumatic brain injury: using the Rivermead Post-concussion Questionnaire to identify predictors of severity

ABSTRACT Background Patients who suffer traumatic brain injury (TBI) often experience a constellation of physical, cognitive, and emotional/behavioral symptoms called “post-concussion symptoms” and subsequent long-term disability. This study aimed to investigate the incidence of persistent post-concussion symptoms and possible predictors of long-term disability focusing on demographic, injury, and psychological factors. It was hoped to identify groups at high risk. Methods A prospective cohort of 1322 individuals admitted with TBI were assessed in a specialist neurorehabilitation clinic at 10 weeks and 1-year post injury between August 2011 and July 2015. The outcome (post-concussion symptoms) was measured using the Rivermead Post-concussion Questionnaire (RPQ) at 1-year post injury. Results At 1 yr, 1131 individuals were identified (>90% follow-up). Over 20% exhibited moderate or severe symptom levels on RPQ. A linear regression model showed that previous psychiatric history, lower Glasgow Coma Scale (GCS), severe CT abnormalities, injury caused by assault, pre-injury unemployment, and inability to return to work at 6 weeks post-injury were associated with worse symptoms at 1 yr. The adjusted R2 of the model was 25.1%. Conclusion These findings confirm the high incidence of post-concussion symptoms at 1 yr and identify certain associated features that increase risk. This may allow targeting of certain groups, e.g., return to work or victims of assault.
Model reduction techniques for linear constant coefficient port-Hamiltonian differential-algebraic systems

Port-based network modeling of multi-physics problems leads naturally to a formulation as port-Hamiltonian differential-algebraic system. In this way, the physical properties are directly encoded in the structure of the model. Since the state space dimension of such systems may be very large, in particular when the model is a space-discretized partial differential-algebraic system, in optimization and control there is a need for model reduction methods that preserve the port-Hamiltonian structure while keeping the (explicit and implicit) algebraic constraints unchanged. To combine model reduction for differential-algebraic equations with port-Hamiltonian structure preservation, we adapt two classes of techniques (reduction of the Dirac structure and moment matching) to handle port-Hamiltonian differential-algebraic equations. The performance of the methods is investigated for benchmark examples originating from semi-discretized flow problems and mechanical multibody systems.
DETECTION OF EXTREMELY BROAD WATER EMISSION FROM THE MOLECULAR CLOUD INTERACTING SUPERNOVA REMNANT G349.7+0.2

We performed Herschel HIFI, PACS, and SPIRE observations toward the molecular cloud interacting supernova remnant G349.7+0.2. An extremely broad emission line was detected at 557 GHz from the ground state transition 110-101 of ortho-water. This water line can be separated into three velocity components with widths of 144, 27, and 4 km s−1. The 144 km s−1 component is the broadest water line detected to date in the literature. This extremely broad line width shows the importance of probing shock dynamics. PACS observations revealed three additional ortho-water lines, as well as numerous high-J carbon monoxide (CO) lines. No para-water lines were detected. The extremely broad water line is indicative of a high velocity shock, which is supported by the observed CO rotational diagram that was reproduced with a J-shock model with a density of 104 cm−3 and a shock velocity of 80 km s−1. Two far-infrared fine-structure lines, [O i] at 145 μm and [C ii] line at 157 μm, are also consistent with the high velocity J-shock model. The extremely broad water line could be simply from short-lived molecules that have not been destroyed in high velocity J-shocks; however, it may be from more complicated geometry such as high-velocity water bullets or a shell expanding in high velocity. We estimate the CO and H2O densities, column densities, and temperatures by comparison with RADEX and detailed shock models.
THE MULTI-WAVELENGTH CHARACTERISTICS OF THE TeV BINARY LS I+61°303

We study the characteristics of the TeV binary LS I+61°303 in radio, soft X-ray, hard X-ray, and gamma-ray (GeV and TeV) energies. The long-term variability characteristics are examined as a function of the phase of the binary period of 26.496 days as well as the phase of the superorbital period of 1626 days, dividing the observations into a matrix of 10 × 10 phases of these two periods. We find that the long-term variability can be described by a sine function of the superorbital period, with the phase and amplitude systematically varying with the binary period phase. We also find a definite wavelength-dependent change in this variability description. To understand the radiation mechanism, we define three states in the orbital/superorbital phase matrix and examine the wideband spectral energy distribution. The derived source parameters indicate that the emission geometry is dominated by a jet structure showing a systematic variation with the orbital/superorbital period. We suggest that LS I+61°303 is likely a microquasar with a steady jet.
On the interpolation of model atmospheres and high-resolution synthetic stellar spectra

We present tests carried out on optical and infrared stellar spectra to evaluate the accuracy of different types of interpolation. Both model atmospheres and continuum normalized fluxes were interpolated. In the first case we used linear interpolation, and in the second linear, cubic spline, cubic-Bezier and quadratic-Bezier methods. We generated 400 ATLAS9 model atmospheres with random values of the atmospheric parameters for these tests, spanning between -2.5 and +0.5 in [Fe/H], from 4500 to 6250 K in effective temperature, and 1.5 to 4.5 dex in surface gravity. Synthesized spectra were created from these model atmospheres, and compared with spectra derived by interpolation. We found that the most accurate interpolation algorithm among those considered in flux space is cubic-Bezier, closely followed by quadratic-Bezier and cubic splines. Linear interpolation of model atmospheres results in errors about a factor of two larger than linear interpolation of fluxes, and about a factor of four larger than high order flux interpolations.
Optimal Pricing under Mixed Logit Choice

In this paper we consider the problem of pricing multiple differentiated products. This is challenging as a price change in one product, not only changes the demand of that particular product, but also the demand for the other products. To address this problem, customer choice models have recently been introduced as these are capable of describing customer choice behavior across differentiated products. In the present paper the objective is to obtain the revenue-maximizing prices when the customer's decision making process is modelled according to a particular customer choice model, namely the mixed logit model. The main advantage of using the mixed logit model, also known as the random coefficients logit model, for this purpose is its flexibility. In the single-product case we establish log-concavity of the optimization problem under certain regularity conditions. In addition, in the multi-product case, we present the results of our extensive numerical experiments. These suggest that the mixed logit model, by taking unobserved customer heterogeneity and flexible substitution patterns into account, can significantly improve the attainable revenue.
Can intrinsic alignments of elongated low-mass galaxies be used to map the cosmic web at high redshift?

Hubble Space Telescope observations show that low-mass ($M_*=10^9\! -\! 10^{10}\, \mathrm{M}_{\odot }$) galaxies at high redshift (z = 1.0–2.5) tend to be elongated (prolate) rather than disky (oblate) or spheroidal. This is explained in zoom-in cosmological hydrodynamical simulations by the fact that these galaxies are forming in cosmic web filaments where accretion happens preferentially along the direction of elongation. We ask whether the elongated morphology of these galaxies allows them to be used as effective tracers of cosmic web filaments at high redshift via their intrinsic alignments. Using mock light cones and spectroscopically confirmed galaxy pairs from the Cosmic Assembly Near-infared Deep Extragalactic Legacy Survey (CANDELS), we test two types of alignments: (1) between the galaxy major axis and the direction to nearby galaxies of any mass and (2) between the major axes of nearby pairs of low-mass, likely prolate, galaxies. The mock light cones predict strong signals in 3D real space, 3D redshift space, and 2D projected redshift space for both types of alignments (assuming prolate galaxy orientations are the same as those of their host prolate haloes), but we do not detect significant alignment signals in CANDELS observations. However, we show that spectroscopic redshifts have been obtained for only a small fraction of highly elongated galaxies, and accounting for spectroscopic incompleteness and redshift errors significantly degrades the 2D mock signal. This may partly explain the alignment discrepancy and highlights one of several avenues for future work.