Miracle-dz/UniFAR-FTUs huggingface dataset:
An evaluation of the impact of parent groups on the treatment of incest victims

Child sexual abuse is on the rise. Per Finkelhor (1984), "child sexual abuse has increased significantly in the last 10-15 years. " With the rising number of sexual abuse cases, a prominent concern for mental health professionals is the issue of treatment for these children. Numerous research studies are being conducted to determine what helps these children progress most effectively through therapy. The study discussed in this paper shows that by providing a group for the victims' parents/caretakers that parallels the victims' group, the progress of the victims is
Single–base pair differences in a shared motif determine differential Rhodopsin expression

Broad versus restricted expression Color vision in fruit flies requires the restricted expression of light-sensing rhodopsins with different wavelength sensitivities in subsets of photoreceptors. However, all photoreceptors express factors that transduce and amplify the visual signal. Rister et al. found that the distinct expression patterns are determined by a highly tunable regulatory motif. Genes that are broadly expressed have a palindromic variant of the motif. Spatially restricted rhodopsin genes display single-base-pair changes that alter the symmetry of the palindrome and are critical for subtype-specific expression. These findings on the differential regulation of gene expression in fly photoreceptors have implications for the evolution of neuronal subtype diversity. Science, this issue p. 1258 Single–base pair changes in a transcription factor binding motif modulate cell type–specific gene expression. The final identity and functional properties of a neuron are specified by terminal differentiation genes, which are controlled by specific motifs in compact regulatory regions. To determine how these sequences integrate inputs from transcription factors that specify cell types, we compared the regulatory mechanism of Drosophila Rhodopsin genes that are expressed in subsets of photoreceptors to that of phototransduction genes that are expressed broadly, in all photoreceptors. Both sets of genes share an 11–base pair (bp) activator motif. Broadly expressed genes contain a palindromic version that mediates expression in all photoreceptors. In contrast, each Rhodopsin exhibits characteristic single-bp substitutions that break the symmetry of the palindrome and generate activator or repressor motifs critical for restricting expression to photoreceptor subsets. Sensory neuron subtypes can therefore evolve through single-bp changes in short regulatory motifs, allowing the discrimination of a wide spectrum of stimuli.
The embodiment of sorcery: Supernatural aggression, belief and envy in a remote Aboriginal community

Anthropologists have long attempted to come to grips with Indigenous Australian sorcery beliefs and especially with the idea that acts with no understandable efficacy bring about illness and death. In this ethnographic interpretation of sorcery beliefs in the remote community of Numbulwar, I follow those few who have attempted to find a link between these apparently harmless acts and real physiological consequences, arguing that the fear of sorcery that pervades Numbulwar contributes directly to the stress of daily life and indirectly to the premature morbidity and mortality of too many lives. Belief is posited as the mechanism whereby the human stress response is activated to a harmful extent, a process in which the projection of envious feelings may often be critical.
Digitization of 3 D Objects for Virtual Museum

Current approaches to digitizing 3D objects for virtual museum can be roughly divided into two categories. One is geometry-based, and the other is image-based. The major advantage of the geometry-based digitization is that the reconstructed 3D models can provide better interactivity for the users to manipulate the 3D virtual objects. Unfortunately, given a 3D artifact, it is usually very expensive, if not impossible, to construct a fine enough 3D model that can generate photo-realistic rendering results. Therefore, we adopt the image-based approach when digitizing 3D artifacts for museums. The digitization results are known as “object movies,” which are in fact interactive movies for displaying 3D objects. The major drawback of the image-based approach is that it does not directly create a 3D geometric model for the 3D artifact, and hence it is not easy to insert the 3D artifact into a 3D environment for virtual exhibition. With our method, we can insert an object movie, in a geometrically consistent way, into a 3D environment that is represented either by a 3D scene model or by a 2D panoramic image. We have applied this technique to develop a stereoscopic kiosk system for virtually exhibiting 3D artifacts of the National Palace Museum.
Best Practices in E government : A review of Some Innovative Models Proposed in Different Countries

--Governments all around the world are heavily investing towards the implementation of e government to improve services to citizens and reduce costs. With the help of ICT, governments can increase efficiency of their operations and can carry out their administrative operations smoothly. Keeping this fact in mind we thought to carry out research identifying the models for international best practices in e government. This paper offers a comparative study of three models and frameworks concerning the development of best practices in e government. The paper reviews each model in detail and provides a view of how each model can help towards the development of best practice in any e government initiative. KeywordsBest Practices, Citizens, E governance Models, Services
The Increase of AMP-activated Protein Kinase during Exercise and its Effect on Reducing Parkinson's Disease Symptoms

Parkinson’s disease (PD) is a neurodegenerative disorder of the central nervous system which is related to disruption of dopaminergic neurons and is considered an abnormality of the brain [1,2]. It is also important to know that, there is an estimation which shows that seven to ten million people worldwide are living with PD. As a result, the most focus should be placed on its treatment or prevention in order to decrease its rate of occurrence.
Apolipoprotein E Polymorphism and Brain Morphology in Mild Cognitive Impairment

Background: The apolipoprotein E (ApoE) genotype has been confirmed as the major genetic risk factor for late-onset Alzheimer’s disease (AD). How the ApoE genotype and brain morphology relate to each other is only partly understood, particularly in mild cognitive impairment, the assumed prestage of AD. Methods: A total of 83 subjects with mild cognitive impairment (aging-associated cognitive decline criteria) were investigated with optimized voxel-based morphometry (VBM). We tested for differences in gray and white matter densities between groups according to their ApoE status, i.e. Ε4 allele noncarriers (n = 42), subjects with one Ε4 allele (n = 27) and subjects with two Ε4 alleles (n = 14). Results: In individuals carrying two Ε4 alleles, VBM revealed a decline in gray matter density predominantly in the medial temporal lobe region. Subjects with a single copy of the Ε4 allele exhibited gray matter atrophy in the right inferior frontal gyrus. With respect to white matter changes, atrophy was only found in subjects homozygous for Ε4 and confined to the right superior and middle temporal gyrus. Conclusion: Our findings support the hypothesis that the ApoE genotype in mild cognitive impairment might be associated with structural changes typically found in the early stages of AD.
Employment Effects of Short and Medium Term Further Training Programs in Germany in the Early 2000s1

We use a new and exceptionally rich administrative data set for Germany to evaluate the employment effects of several short and medium term further training programs in the early 2000s. Building on the work of Sianesi (2003, 2004), we apply propensity score matching methods in a dynamic, multiple treatment framework in order to address program heterogeneity and dynamic selection into programs. Our results suggest that in West Germany both short-term and medium-term programs may have considerable employment effects for certain population subgroups, and that short-term programs are surprisingly effective when compared to the traditional and more expensive longer-term programs. With a few exceptions, we find little evidence for significant treatment effects in East Germany.
Neonatal inflammation produces selective behavioural deficits and alters N‐methyl‐d‐aspartate receptor subunit mRNA in the adult rat brain

Peripheral inflammation causes production of central cytokines that alter transmission at the N‐methyl‐d‐aspartate receptor (NR). During development, NRs are important for synaptic plasticity and network connectivity. We therefore asked if neonatal inflammation would alter expression of NRs in the brain and behavioural performance in adulthood. We gave lipopolysaccharide (LPS) (100 µg/kg, i.p.) or saline to male rats on postnatal day (P)5, P14, P30 or P77. Subsequently we assessed mRNA levels of the NR1, NR2A, B, C and D subunits in the hippocampus and cortex either acutely (2 h) or in adulthood using real‐time reverse transcriptase‐polymerase chain reaction. We explored learning and memory behaviours in adult rats using the Morris water maze and contextual fear conditioning paradigms. Hippocampal NR1 mRNA was acutely increased in the P5‐ and P77‐treated rats but was reduced in adults treated with LPS at P5, P30 and P77. P14 LPS‐treated rats showed few acute changes but showed pronounced increases in NR2A, B, C and D subunit mRNA later in adulthood. The cortex displayed relatively few acute changes in expression in the neonatal‐treated rats; however, it showed robust changes in NR2B, C and D mRNA in all groups given LPS in adulthood. Behavioural deficits were observed specifically in the P5 and P30 LPS‐treated groups in the water maze probe trial and fear conditioning tests, consistent with hippocampal NR1 mRNA down‐regulation. Thus, a single bout of inflammation during development can programme specific and persistent differences in NR mRNA subunit expression in the hippocampus, which could be associated with behavioural and cognitive deficits in adulthood.
Wavelet and Histogram Based Energy Feature Image Retrieval (W&HBEFIR)

The Wavelet and Histogram Based Energy Feature Image Retrieval, using features like Color, texture and Shape, called W&HBEFIR (Wavelet and Histogram Based Energy Feature Image Retrieval). The texture and color features are extracted through wavelet transformation & Histogram. The increased need of W&HBEFIR technique can be found in a number of different domains such as Data Mining, Education, Medical Imaging, Crime Prevention, Weather forecasting, Remote Sensing and Management of Earth Resources.
Finite element analysis of neuronal electric fields: the effect of heterogeneous resistivity

Simulation of extracellular fields is one of the substantial methods used in the area of computational neuroscience. Its most common usage is validation of experimental methods as EEG and extracellular spike recordings or modeling of physiological phenomena which can not be easily determined empirically. Continuous experimental work has been re-raising the importance of polarization effects between neuronal structures to neuronal communication. As this effects relies on very small potential changes, better modeling methods are necessary to quantify the weak electrical fields in the microscopic scale in a more realistic way. An important factor of influence on local field effects in the hippocampal formation is the heterogeneous resistivity of extracellular tissue. The vast majority of modeling studies consider the extracellular space to be homogeneous while experimentally, it has been shown that the stratum pyramidale has two times higher resistivity then other hippocampal layers. Common simulation methods for extracellular electrical fields based on the point source approximation are bound to describe the resistance of the space with a single, linear factor. We propose that models should be based on the space- and time-dependent Maxwell equations in order to account for heterogeneous properties of the extracellular space and specific arrangements of neurons in dense hippocampal layers. To demonstrate the influence of heterogeneous extracellular resistivity and neuronal spatial orientation on modeling results, we combine solutions of classical compartment models with spatiotemporal PDEs solved by the FEM. With the help of these methods, we show that the inclusion of heterogeneous resistivity has a substantial impact on voltages in close proximity to emitting neurons, increasing the extracellular potentials substantially compared to the homogeneous variant.
The x-Kernel: An Architecture for Implementing Network

[32] Sun Microsystems,Inc., Mountainview, Calif. RemoteProcedure Call ProgrammingGuide, Feb. 1986. [33] C. P. Thacker , L. C. Stewart,andE. H. Satterthwaite.Firefly: A multiprocessorworkstation.IEEE TransactionsonComputers , 37(8):909–920, Aug. 1988. [34] USC. Transmissioncontrol protocol. RequestFor Comments793, USC Information Sciences Institute,Marina del Ray, Calif. , Sept.1981. [35] R. van Renesse,H. van Staveren,and A. S. Tanenbaum.Performanceof the world’s fastestdistributedoperatingsystem.OperatingSystemsReview, 22(4):25–34,Oct. 1988. [36] R. W. Watsonand S. A. Mamrak. Gaining efficiency in transportservicesby appropriatedesign andimplementationchoices.ACM TransactionsonComputerSystems , 5(2):97–120,May 1987. [37] B. B. Welch. The Sprite remote procedurecall system. Technical Report UCB/CSD 86/302, University of California Berkeley, Berkeley, Calif. , June1988.
Asynchronous accelerator with RFQ injection for active longitudinal compression of accelerated bunches

An asynchronous accelerator is described, in which the principle of its operation permits the active longitudinal bunch compression of accelerated proton beams, to overcome the space charge limitation effects of intense bunches. It is shown that accelerated bunches from an RFQ linac can be adapted for Asynchronac injection for a multiple of choices in the acceleration frequencies of the RFQ and the Asynchronac. The offered new type of accelerator system is especially suitable to accelerate proton beams for up to 100MeV energy and hundreds of mA average current.
Influence of Cellular Composition and Exogenous Activation on Growth Factor and Cytokine Concentrations in Canine Platelet-Rich Plasmas

Objective The purposes of this study were to (1) evaluate correlations among platelet, leukocyte, growth factor, and cytokine concentrations in canine platelet-rich plasmas (PRPs) produced from five different canine PRP-concentrating systems and (2) compare the effects of different activation protocols on platelet activation and growth factor release from one of these PRPs. Methods PRP was made using blood from 15 dogs and each of 5 different PRP systems in a cross-over design. Complete blood counts were performed to quantify platelet and leukocyte concentrations. PRPs were activated, or not, according to manufacturer instructions, and transforming growth factor-β1 (TGF-β1), platelet-derived growth factor-BB (PDGF-BB), vascular endothelial growth factor, and tumor necrosis factor-alpha (TNF-α) were quantified. Differences among platelet, leukocyte, and growth factor concentration were compared among the different systems. Correlations between platelet and anabolic growth factor concentrations were assessed. Subsequently, PRP was made from 12 additional dogs using one of the devices. Each PRP was divided into three aliquots that were activated with calcium chloride (CaCl2), human γ-thrombin (HGT), or not activated. Expression of CD62P and platelet-bound fibrinogen (CAP1) was quantified for each activation group. Concentrations of TGF-β1, PDGF-BB, and TNF-α were also quantified for each activation group and a fourth group that was frozen/thawed. Differences among activation groups were assessed by a Friedman test. Results There were statistically significant differences among the PRPs made with difference devices with regard to platelet, leukocyte, TGF-β1, and PDGF-BB concentrations (p < 0.0001). There were weak to moderate correlations (R2 = 0.07–0.58) between platelet and anabolic growth factor concentrations but it appeared that activation had a greater effect on growth factor concentration than did cellular composition. Intentional platelet activation significantly increased CD62P and CAP1 expression as well as TGF-β1 and PDGF-BB concentrations in the one PRP in which all activation methods were assessed. Activation with HGT resulted in the greatest platelet activation, and CaCl2 and freeze/thaw elicited moderate increases in either growth factor release or CD62P and CAP1 expression. Conclusion There are positive correlations between platelet and anabolic growth factor concentrations in canine PRPs. However, intentional platelet activation has a greater effect on growth factor delivery than platelet concentration. Thrombin provides more robust activation than CaCl2.
Signal processing requirements for step detection using wrist-worn IMU

This paper studies how the accuracy of the step detection algorithm of a pedestrian dead-reckoning (PDR) system is affected by the sampling frequency and the filtering of the data gathered from a wrist-worn inertial measurement unit (IMU). On the one hand, results show that sensors sampling rate can be reduced and a similar accuracy can still be obtained, what it is very interesting for energy saving purposes. However, a low sampling frequency requires a finer tuning of the algorithm's parameters. On the other hand, the application of a filter to the data gathered from the sensors is always recommended, in order to get some performance improvement. Different types of filters can be used in function of the value of the sampling frequency.
Opportunities of improvement in the management of pancreatic and periampullary tumors

Abstract Objective. The first objective of the present study was to identify opportunities of improvement for clinical practice, assessed by local quality indicators, then to analyze possible reasons why we did not reach defined treatment quality measures. The second objective was to characterize patients, considered unresectable according to present criteria, for future arrangement of interventional studies with improved patient selection. Material and methods. Prospective observational cohort study from October 2008 to December 2010 of patients referred to the authors' institution with suspected pancreatic or periampullary neoplasm. Results. Of 330 patients, 135 underwent surgery, 195 did not, 129 due to unresectable malignancies. The rest had benign lesions. Perioperative morbidity rate was 32.6%, mortality 0.7%. Radical resection (R0) was obtained in 23 (41.8%) of 55 patients operated for pancreatic adenocarcinoma and 6.3% underwent reconstructive vascular surgery. Diagnostic failure/delay resulted in unresectable carcinoma, primarily misconceived as serous cystic adenoma in two patients. One resected lesion turned out to be focal autoimmune pancreatitis. One case with misdiagnosed cancer was revised to be a pseudoaneurysm. Palliative treatment was offered to 144 patients with malignant tumors, 62 due to locally advanced disease and all pancreatic adenocarcinomas. Conclusions. Quality improvement opportunities were identified for patient selection and surgical technique: Too few patients underwent reconstructive vascular surgery. The most important quality indicators are those securing resectional, radical (R0) surgery. Altogether 143 patients (57.9%) of those with malignant tumors were found unresectable, most of these patients are eligible for inclusion in future interventional studies with curative and/or palliative intention.
Les constituants introduits par des marqueurs de thématisation en français face aux compléments spatio-temporels antéposés : une analyse prosodique

This paper discusses the prosodic properties of sen tence-initial spatio-temporal adverbials and of PPs introduced by so-called 'thematic markers' ( TMCs), such as en ce qui concerne ('as for') or du point de vue de ('with regard to'). Their function s to indicate the aboutness-topic (a.o. Reinhart 1 981, Gundel 1989, Lambrecht 1994) (1) or the topic Chine se style (Chafe 1976) (2). (1) Concernant le programme, il doit différer selon les universités et les profs. (2) Mais quand on peut il faut impérativement regar der BBC News. En ce moment, au niveau de l'info, ils sont vraiment au top. (YCCQA, De Smet 2009) Mertens (2008) hypothesizes that in certain syntact ic constructions such as left dislocations, (pseudo-)clefts and certain adjuncts, the articulat ion between the left detached element (the dislocat ed element, the focus of the cleft, the adjunct) and t he main clause is followed by a major prosodic boundary, i.e. they end on a relative high pitch le vel. It appears from our corpus that most TMCs end o such a major prosodic boundary (73%). As for senten ce-i itial spatio-temporal PPs, only 41% end on a major prosodic boundary. There are two important differences between TMCs an d sentence-initial spatio-temporal PPs which explain that a strong prosodic boundary at th e end of a TMC is more frequent than at the end of sentence-initial spatio-temporal adverbials. Semantically, sentence-initial spatio-temporal adve rbials always limit the application range of the main clause, but not all TMCs affect the truth values of the proposition. Some can be omitted with out changing the signification of the clause. On the syntactic level, sentence-initial spatio-tem poral adverbials can always appear in the scope of a cleft or can be moved towards the end of the utterance without the proposition becomes ungrammatical. TMCs which affect the truth values o f the proposition can also appear in the scope of the cleft or can be moved to the end of the proposi tion. TMCs which do not affect the truth values of the proposition do not allow these syntactic tests. Possibility of clefting, movement and specification f the main clause are used as tests (a.o. Melis 1983, Blanche-Benveniste et al. 1990) to show whether a constituent is linked to the verb phrase . This paper shows that sentence-initial spatial-temp oral PPs are linked to the verb phrase, but that th is is not the case for all TMCs. These syntactic and sema ntic observations explain the high frequency of the strong prosodic boundary at the end of a TMC.
IMULATION OF S NOOZE A TTACK IN L EACH

Wireless Sensor Network (WSN) consists of large number of sensor nodes capable of forming instantaneous network with dynamic topology. Each node simultaneously as both router and host. Number of nodes in a WSN can vary either due to the mobility or death of nodes due to drained conditions. Low Energy Aware Cluster Hierarchy (LEACH) is a most popular dynamic clustering protocol for WSN. Deployment in unattended environment, limited memory, limited power and low computational power of a sensor node make these networks susceptible to attacks launched by malicious nodes. This paper provides an overview of LEACH protocol and how LEACH can be compromised by malicious nodes. We propose a attack on LEACH – Snooze attack. This paper we present a way to simulate this attack on NS-2 which is demonstrative on throughput. We observe that during simulation throughput drops as an effect of attack. It is observed that the effect of the attack gets aggregated as we increase the number of attackers.