Miracle-dz/UniFAR-FTUs huggingface dataset:
Automatically Evading IDS Using GP Authored Attacks

A mimicry attack is a type of attack where the basic steps of a minimalist 'core' attack are used to design multiple attacks achieving the same objective from the same application. Research in mimicry attacks is valuable in determining and eliminating weaknesses of detectors. In this work, we provide a genetic programming based automated process for designing all components of a mimicry attack relative to the Stide detector under a vulnerable Traceroute application. Results indicate that the automatic process is able to generate mimicry attacks that reduce the alarm rate from ~65% of the original attack, to ~2.7%, effectively making the attack indistinguishable from normal behaviors
Surveying the Relationship between Social Capital and Knowledge Management Implementation at Custom House of Imam Khomeini Port

The study has been done to determine the relationship social capital dimensions (structural, cognitive and relational) as independent variables and knowledge management dimensions (knowledge strategy and objectives, knowledge creation and acquisition, knowledge maintenance and documentation, knowledge dissemination, knowledge application, knowledge evaluation and feedback) as dependent variable. We determined the amount of the sample size with the used of Cochran sampling method which the statistical sample is 102 of these employees which have been selected through the simple random sampling method. To gathering of data, we used a questionnaire with 41 items. Questionnaires reliability was estimated by calculating Cronbach’s Alpha. To analyze the data resulted from collected questionnaires deductive and descriptive statistical methods are used. The results Kolmogorov-Smirnov Test shows the test distribution is Normal. So we can use Pearson Correlation coefficients to test the hypothesis of the research. Findings show that there is significant relationship between Social capital and Knowledge management dimensions (knowledge strategy and objectives, knowledge creation and acquisition, knowledge maintenance and documentation, knowledge dissemination, knowledge application, knowledge evaluation and feedback).
A Survey on Routing Mechanism and Techniques in Vehicle to Vehicle Communication (VANET)

Now a day, one of the most attractive research topics in the area of Intelligent Traffic Control is Intervehicle communication. In V2V communication or we can also called VANET i.e. vehicular ad-hoc network; a vehicle can communicate to its neighboring vehicles even in the absence of a central Base Station. The concept of this direct communication is to send vehicle safety messages one-to-one or oneto-many vehicles via wireless connection. Such messages are usually short in length and have very short lifetime in which they must reach at the destination. The Inter-vehicle communication system is an adhoc network with high mobility and changing number of nodes, where mobile nodes dynamically create temporary networks and transferring messages from one node to others by using multiple hops due to limitation of short range. The routing in vehicular Ad hoc Networks (VANET) has attracted many attentions during the last few years. So in this paper we are focusing on the routing concept for the VANET i.e. principles for routing, decomposition of the routing function and requirement. The data delivery through Vehicular Ad-hoc Networks is challenging since it must efficiently handle rapid topology changes and a fragmented network.
Laser microfabrication of metallic parts

In this paper two processes of microfabrication technology are investigated. In the first part, laser generating process which is largely affected by the beam interaction time is described. In the second part, selective laser sintering of metallic powder shall be discussed. The results show that the two metal liquid phase sintering is most effective in the selective laser sintering of the metallic powder comprising of high and low melting point. Whereas in the generating process the beam interaction time greatly affect the structural development of the product with respect to its strength and quality. A few examples are demonstrated briefly.
Gait analysis comparing Parkinson's disease with healthy elderly subjects.

UNLABELLED There is a lack of studies comparing the kinematics data of idiopathic Parkinson's disease (IPD) patients with healthy elder (HE) subjects, and when there is such research, it is not correlated to clinical measures. OBJECTIVE To compare the spatio-temporal and kinematic parameters of Parkinsonian gait with the HE subjects group and measure the relation between these parameters and clinical instruments. METHOD Twelve patients with IPD and fifteen HE subjects were recruited and evaluated for clinical instruments and gait analysis. RESULTS There were statistically significant differences between HE group and the IPD group, in stride velocity, in stride length (SL), and in the hip joint kinematic data: on initial contact, on maximum extension during terminal contact and on maximum flexion during mid-swing. Regarding the clinical instruments there were significant correlated with in stride velocity and SL. CONCLUSION Clinical instruments used did not present proper psychometric parameters to measure the IPD patient's gait, while the 3D system characterized it better.
Immense Essence of Excellence: Marine Microbial Bioactive Compounds

Oceans have borne most of the biological activities on our planet. A number of biologically active compounds with varying degrees of action, such as anti-tumor, anti-cancer, anti-microtubule, anti-proliferative, cytotoxic, photo protective, as well as antibiotic and antifouling properties, have been isolated to date from marine sources. The marine environment also represents a largely unexplored source for isolation of new microbes (bacteria, fungi, actinomycetes, microalgae-cyanobacteria and diatoms) that are potent producers of bioactive secondary metabolites. Extensive research has been done to unveil the bioactive potential of marine microbes (free living and symbiotic) and the results are amazingly diverse and productive. Some of these bioactive secondary metabolites of microbial origin with strong antibacterial and antifungal activities are being intensely used as antibiotics and may be effective against infectious diseases such as HIV, conditions of multiple bacterial infections (penicillin, cephalosporines, streptomycin, and vancomycin) or neuropsychiatric sequelae. Research is also being conducted on the general aspects of biophysical and biochemical properties, chemical structures and biotechnological applications of the bioactive substances derived from marine microorganisms, and their potential use as cosmeceuticals and nutraceuticals. This review is an attempt to consolidate the latest studies and critical research in this field, and to showcase the immense competence of marine microbial flora as bioactive metabolite producers. In addition, the present review addresses some effective and novel approaches of procuring marine microbial compounds utilizing the latest screening strategies of drug discovery.
A Model Based Approach for Vessel Caliber Measurement in Retinal Images

The diagnostic signature of many microvasculature diseases like diabetes mellitus, hypertension and arteriosclerosis includes the changes incurred in the diameter of retinal blood vessels. Therefore estimation of precise vascular widths is a critical and demanding process in automated retinal image analysis. This paper proposes an automated system to measure the vessel caliber in the retinal images of multi-ethnic school children. The diameter measurement is based on the detection of the centerline pixels from a vessel probability map image, determining the vessel orientation at these pixels, extracting the vessel segments and later using a two dimensional model, which is optimized to fit various types of intensity profiles of vessel segments. The width is then estimated from parameters of the optimized model. The method is also used to explore the relationship between the average vessel width and the background pigmentation of the retinal image by analyzing monochromatic representations of different color spaces.
Zinc-alpha 2-glycoprotein has ribonuclease activity.

Zinc-alpha 2-glycoprotein (Zn alpha 2gp) is widely distributed in body fluids and in various epithelia; its gene has been completely sequenced, but its function has long remained elusive. We have found that Zn alpha 2gp has RNase activity, comparable to onconase but two orders of magnitude less than RNase A. The RNase activity of Zn alpha 2gp is characterized by maxima in pH at 7.5, in ionic strength at 50 mM NaCl, and in temperature at 60 degreesC. It is strongly inhibited by ZnCl2, but unaffected by MgCl2. It is partially inactivated (down to 20%) by the placental RNase inhibitor. On synthetic polyribonucleotide substrates, the RNase activity of Zn alpha 2gp is specific for pyrimidine residues [poly(C) and poly(U) equally] and cleaves only single-stranded RNA. For onconase, it has been demonstrated that the RNase activity depends on pyroglutamic acid (pyr 1) as the N-terminus; Zn alpha 2gp also has pyr 1, while RNase A does not. Alignment of the amino acid sequences of Zn alpha 2gp and onconase or RNase A reveals only modest matches. Despite the more substantial overall structural homology of Zn alpha 2gp to class I major histocompatibility complex proteins, Zn alpha 2gp has not been proven to be associated with the immune response and, conversely, we could not detect RNase activity in six class I HLA heavy chains.
Simultaneous Evaluation of Multiple I/O Strategies

We present a framework for simulating the performance obtained by different I/O system mechanisms and algorithms at the same time, and for dynamically turning them on and off to improve the overall system performance. A key element of this framework is the the design and implementation of a virtual disk inside the Linux kernel. Our virtual disk creates a virtual block device which is able to simulate any hard drive with a negligible overhead, without interfering with regular I/O requests. We describe the potential of our proposal in REDCAP, a RAM-based disk cache which is dynamically activated/deactivated according to the throughput achieved. The results show that, by using our virtual disk, REDCAP obtains its maximum possible improvements: up to 80% for workloads with some spatial locality, and the same performance as a ``normal system'' for workloads with random or large sequential reads.
Slope failures in municipal solid waste dumps and landfills: a review

Between 1977 and 2005 six large-scale failures of municipal solid waste dumps and landfills have been recorded in the technical literature. The volumes of waste mobilized in the failures varied from 10—12 000 m3 in a failure that killed nearly 300 people to 1.5 million m3 in a failure that caused no deaths or injuries. Of the six failures, four occurred in dumps that, as far as is known, had not been subjected to any prior technical investigation of their shear stability. The remaining two failures occurred in engineer-designed landfills, one of which practised leachate recirculation, and the other co-disposed of liquid waste along with solid waste. The paper reviews, describes and analyses the failures and summarizes their causes.
Simulation of elliptical patterns based on grinding with wheel dressed by elliptical tool

ABSTRACT Dressing is a sharpening operation aimed to produce a specific groove shape on the active surface of the wheel. The preparation of grinding tools in special way is the most important enabling factor in the grinding process. It greatly influences the subsequent geometry of the workpiece. As the groove shape of the wheel surface determines the shape of the surface patterns, therefore, it is essential to produce desired groove on the wheel cutting surface before grinding. Therefore, an elliptical groove surface pattern model is proposed based on grinding with dressed wheel. An elliptical tip tool is used for the dressing process to make grooves on the wheel instead of sharp tip tool or rounded tip tool in the previous work. The dressing tool passes helically over the surface of the grinding wheel for making grooves. After that, the grooved wheel passes over the flat surface to generate elliptical patterns. The results showed the three-dimensional geometry of the surface patterns with elliptical groove which are uniformly distributed on the workpiece. An experiment is carried out for the verification of the simulation results and it is revealed that the simulation results agreed well with the experiment.
Closing the IT Development-Operations Gap: The DevOps Knowledge Sharing Framework

Although DevOps has been heralded as a novel paradigm to overcome the traditional boundaries between IT Development (Dev) and IT Operations (Ops) teams, many IT organizations lack guidance on how to implement this paradigm in practice. This design research provides a framework that can aid organizations assess not only their status in fulfilling recommended DevOps principles, practices and tool use―given the central role of knowledge sharing in software delivery, our framework also includes required knowledge conversion between Dev and Ops teams by building on the dimensions of the widely recognized SECI model [1]. We evaluated the proposed DevOps knowledge-sharing framework (DOKS) in the context of a small IT service firm and a large financial services company. Our findings provide that the DOKS framework can help organisations by sensitizing the two teams’ awareness for crucial DevOps elements. Moreover, we discuss how DevOps implementation approaches may differ between smaller and larger IT organizations.
Optical Solitons and Wave-particle Duality

We investigate the propagation of optical solitons interacting with linear defects in the medium. We show that solitons exhibit a wave-particle dualism versus power, i.e., depending on the relative size of soliton and defect, responsible for a soliton trajectory dependent on its waist. The parallelism between optics and other areas of physics has been addressed in several cases, including fluid dynamics [1], nonrelativistic [2] and relativistic quantum mechanics [3], general relativity [4], solid state [5] and condensed matter physics [6]. In optics, an important role is played by solitons, i.e., optical wave packets undergoing transverse confinement via nonlinear effects in time or space [7]. Spatial [8] and temporal [9] solitons were first discussed in pure Kerr media, but their existence and features were later investigated both experimentally and theoretically in materials encompassing various light-matter nonlinear interactions [7,10,11]. Fundamental solitons often behave in a particlelike fashion: their transverse field distribution is strongly peaked in space/time, they are robust to external perturbations and survive as independent entities to a large set of collisions. Therefore, solitary wave packets are an ideal bench for investigating the wave-particle duality in a macroscopic scale [12–14]. Soliton interactions with inhomogeneities have been studied with reference to both longitudinally infinite [15–17] and pointlike defects [18] in refractive index, as well as to pointlike perturbations in nonlinearity [18,19], at the interface between two nonlinear media [20,21] and across a linear potential barrier [22,23]. In this Letter we try to elucidate the dual nature of self-trapped optical wave packets by investigating the interaction of solitons with localized perturbations (defects) in an otherwise uniform linear refractive index environment, showing their transition from particle to wavelike as the defect remains nearly uniform or varies appreciably across the soliton profile, respectively. We look for solutions of the well-known one-dimensional nonlinear Schrödinger equation (NLSE) governing the nonlinear paraxial propagation of light in the form of temporal pulses in fibers or of beams in planar guides. Hereafter, we focus on the latter case, but all the results remain valid in both cases. We assume a linear index defect n L (x=w p , z) (w p is its width along x) super-posed to an isotropic Kerr medium with background index n 0 and intensity-dependent coefficient n 2. For an electric field of amplitude A, the effective potential
Histone Deacetylases Play a Major Role in the Transcriptional Regulation of the Plasmodium falciparum Life Cycle

The apparent paucity of molecular factors of transcriptional control in the genomes of Plasmodium parasites raises many questions about the mechanisms of life cycle regulation in these malaria parasites. Epigenetic regulation has been suggested to play a major role in the stage specific gene expression during the Plasmodium life cycle. To address some of these questions, we analyzed global transcriptional responses of Plasmodium falciparum to a potent inhibitor of histone deacetylase activities (HDAC). The inhibitor apicidin induced profound transcriptional changes in multiple stages of the P. falciparum intraerythrocytic developmental cycle (IDC) that were characterized by rapid activation and repression of a large percentage of the genome. A major component of this response was induction of genes that are otherwise suppressed during that particular stage of the IDC or specific for the exo-erythrocytic stages. In the schizont stage, apicidin induced hyperacetylation of histone lysine residues H3K9, H4K8 and the tetra-acetyl H4 (H4Ac4) and demethylation of H3K4me3. Interestingly, we observed overlapping patterns of chromosomal distributions between H4K8Ac and H3K4me3 and between H3K9Ac and H4Ac4. There was a significant but partial association between the apicidin-induced gene expression and histone modifications, which included a number of stage specific transcription factors. Taken together, inhibition of HDAC activities leads to dramatic de-regulation of the IDC transcriptional cascade, which is a result of both disruption of histone modifications and up-regulation of stage specific transcription factors. These findings suggest an important role of histone modification and chromatin remodeling in transcriptional regulation of the Plasmodium life cycle. This also emphasizes the potential of P. falciparum HDACs as drug targets for malaria chemotherapy.
Interface Discharge Behaviour at Polypropylene Nanocomposites and Silicone Rubber under AC Voltage

Polypropylene has a great electrical property and may be used as primary insulating material in electrical power cable. In cable accessory, the field distribution is often distorted since the very complicated physical structure, which makes interface discharge between PP and cable joint insulation easy to happen. Polymer based nanocomposites has recently received a lot of attentions, which can offer a better insulation property than the neat polymer. In order to improve the electrical property of the PP/SiR interface, nano-sized MgO filler has been adding into PP matrix to form the socalled PP/MgO nanocomposites. The interface discharge behavior between the nanocomposites and the SiR have been studied. Obtained results showed that with the increase in the nano-particle content from 0 wt% to 5 wt%, the interface breakdown strength firstly increases but then decreases. A proper content of 3 wt% nano-sized MgO adding can improve the interface breakdown strength by a fact of 3.5. It is suggested that the interface breakdown strength can be enhanced through the adding of nano-sized MgO. KeywordsPolypropylene; Nanocomposites; Silicone Rubber;
Multi-modal SEM/FIB-SEM for Precise Targeting of Cell-Cell Junctions in Human Pancreatic Islets.

Although much research has been done to generate EM-resolution 3D models of rodent islets [1,2], the use of human islets has been relatively unexplored. To analyze these, we developed a pipeline to rapidly and precisely screen fixed and stained human islets for high-resolution focused ion beam (FIB) nanotomography. Upon close examination, we find physical evidence of granule exchange between islet endocrine cells, as well as junctional structures previous not described in islets. The novelty of this work is two-fold: the application of FIB-SEM to studying human islet tissue, and the discovery of new structural elements that can potentially link morphological and functional aspects of islet anatomy.
The Kinesin-Related Protein, Hset, Opposes the Activity of Eg5 and Cross-Links Microtubules in the Mammalian Mitotic Spindle

We have prepared antibodies specific for HSET, the human homologue of the KAR3 family of minus end-directed motors. Immuno-EM with these antibodies indicates that HSET frequently localizes between microtubules within the mammalian metaphase spindle consistent with a microtubule cross-linking function. Microinjection experiments show that HSET activity is essential for meiotic spindle organization in murine oocytes and taxol-induced aster assembly in cultured cells. However, inhibition of HSET did not affect mitotic spindle architecture or function in cultured cells, indicating that centrosomes mask the role of HSET during mitosis. We also show that (acentrosomal) microtubule asters fail to assemble in vitro without HSET activity, but simultaneous inhibition of HSET and Eg5, a plus end-directed motor, redresses the balance of forces acting on microtubules and restores aster organization. In vivo, centrosomes fail to separate and monopolar spindles assemble without Eg5 activity. Simultaneous inhibition of HSET and Eg5 restores centrosome separation and, in some cases, bipolar spindle formation. Thus, through microtubule cross-linking and oppositely oriented motor activity, HSET and Eg5 participate in spindle assembly and promote spindle bipolarity, although the activity of HSET is not essential for spindle assembly and function in cultured cells because of centrosomes.
In situ measurements of external pH and optical density oscillations in Dictyostelium discoideum aggregates

In situ measurements of extracellular pH by means of microelectrodes and in situ measurements of optical density were performed on aggregating cells of Dictyostelium discoideum. Early aggregation stage AX2 cells showed sinusoidal pH oscillations, which could be inhibited by the specific relay inhibitor caffeine, indicating that they were coupled to cAMP oscillations. Sometimes biphasic pH oscillations were found, which can be explained by the superposition of two harmonic pH oscillations. These harmonic oscillations might arise by gating of the cAMP signal; a part of the cells respond to every cAMP signal and another subpopulation to every second cAMP pulse. Late aggregation- stage cells showed complex changes of the extracellular pH, which could be inhibited by caffeine. Optical density measurements of wave propagation in aggregation streams of HG220 also revealed gating behavior. In addition to sinusoidal optical density oscillations, biphasic and still more complex oscillations were observed.