Miracle-dz/UniFAR-FTUs huggingface dataset:
The numerical simulation tool for the MAORY multiconjugate adaptive optics system

The Multiconjugate Adaptive Optics RelaY (MAORY) is and Adaptive Optics module to be mounted on the ESO European-Extremely Large Telescope (E-ELT). It is an hybrid Natural and Laser Guide System that will perform the correction of the atmospheric turbulence volume above the telescope feeding the Multi-AO Imaging Camera for Deep Observations Near Infrared spectro-imager (MICADO). We developed an end-to-end Monte- Carlo adaptive optics simulation tool to investigate the performance of a the MAORY and the calibration, acquisition, operation strategies. MAORY will implement Multiconjugate Adaptive Optics combining Laser Guide Stars (LGS) and Natural Guide Stars (NGS) measurements. The simulation tool implement the various aspect of the MAORY in an end to end fashion. The code has been developed using IDL and use libraries in C++ and CUDA for efficiency improvements. Here we recall the code architecture, we describe the modeled instrument components and the control strategies implemented in the code.
Antimicrobial Treatment on a Catheter-Related Bloodstream Infection (CRBSI) Case Due to Transition of a Multi-Drug-Resistant Ralstonia mannitolilytica from Commensal to Pathogen during Hospitalization

Despite its commonly overlooked role as a commensal, Ralstonia mannitolilytica becomes an emerging global opportunistic human pathogen and a causative agent of various infections and diseases. In respiratory illnesses, including cystic fibrosis and chronic obstructive pulmonary disease (COPD), R. mannitolilytica is also identified presumably as colonizer. In this study, one distinctive clone of R. mannitolilytica was firstly identified as colonizer for the first 20 days during hospitalization of a patient. It was then identified as a causative agent for catheter-related bloodstream infection with negative identification after effective treatment, verifying its transition from commensal to pathogen. In conclusion, we provide convincing evidence that during hospitalization of a patient, R. mannitolilytica transitioned from commensal to pathogen in the respiratory tract leading to catheter-related bloodstream infection (CRBSI).
Resonance fluorescence in ultrafast and intense x-ray free-electron-laser pulses

The spectrum of resonance fluorescence is calculated for a two-level system excited by an intense, ultrashort x-ray pulse made available for instance by free-electron lasers such as the Linac Coherent Light Source. We allow for inner-shell hole decay widths and destruction of the system by further photoionization. This two-level description is employed to model neon cations strongly driven by x rays tuned to the 1s 2p-1 --> 1s-1 2p transition at 848 eV; the x rays induce Rabi oscillations which are so fast that they compete with Ne 1s-hole decay. We predict resonance fluorescence spectra for two different scenarios: first, chaotic pulses based on the self-amplified spontaneous emission principle, like those presently generated at x-ray free-electron-laser facilities and, second, Gaussian pulses which will become available in the foreseeable future with self-seeding techniques. As an example of the exciting opportunities derived from the use of seeding methods, we predict, in spite of above obstacles, the possibility to distinguish at x-ray frequencies a clear signature of Rabi flopping in the spectrum of resonance fluorescence.
M32 Analogs? A Population of Massive Ultra-compact Dwarf and Compact Elliptical Galaxies in Intermediate-redshift Clusters

We report the discovery of relatively massive, M32-like ultra compact dwarf (UCD) and compact elliptical (CE) galaxy candidates in massive galaxy clusters imaged by the Cluster Lensing And Supernova survey with Hubble (CLASH) survey. Examining the nearly unresolved objects in the survey, we identify a sample of compact objects concentrated around the cluster central galaxies with colors similar to cluster red sequence galaxies. Their colors and magnitudes suggest stellar masses around . More than half of these galaxies have half-light radii smaller than 200 pc, falling into the category of massive UCDs and CEs, with properties similar to M32. The properties are consistent with a tidal stripping origin, but we cannot rule out the possibility that they are early-formed compact objects trapped in massive dark matter halos. The 17 CLASH clusters studied in this work on average contain 2.7 of these objects in their central 0.3 Mpc and 0.6 in their central 50 kpc. Our study demonstrates the possibility of statistically characterizing UCDs/CEs with a large set of uniform imaging survey data.
DEEP GALEX OBSERVATIONS OF THE COMA CLUSTER: SOURCE CATALOG AND GALAXY COUNTS

We present a source catalog from a deep 26 ks Galaxy Evolution Explorer (GALEX) observation of the Coma cluster in the far-UV (FUV; 1530 Å) and near-UV (NUV; 2310 Å) wavebands. The observed field is centered ∼0. °9 (1.6 Mpc) southwest of the Coma core in a well-studied region of the cluster known as “Coma-3. ” The entire field is located within the apparent virial radius of the Coma cluster, and has optical photometric coverage with Sloan Digital Sky Survey (SDSS) and deep spectroscopic coverage to r ∼ 21. We detect GALEX sources to NUV = 24.5 and FUV = 25.0, which corresponds to a star formation rate of ∼10−3 M☉ yr−1 for galaxies at the distance of Coma. We have assembled a catalog of 9700 galaxies with GALEX and SDSS photometry, including 242 spectroscopically confirmed Coma member galaxies that span a large range of galaxy types from giant spirals and elliptical galaxies to dwarf irregular and early-type galaxies. The full multi-wavelength catalog (cluster plus background galaxies) is ∼80% complete to NUV = 23 and FUV = 23.5. The GALEX images presented here are very deep and include detections of many resolved cluster members superposed on a dense field of unresolved background galaxies. This required a two-fold approach to generating a source catalog: we used a Bayesian deblending algorithm to measure faint and compact sources (using SDSS coordinates as position prior), and used the GALEX pipeline catalog for bright and/or extended objects. We performed simulations to assess the importance of systematic effects (e.g., object blends, source confusion, Eddington Bias) that influence the source detection and photometry when using both methods. The Bayesian deblending method roughly doubles the number of source detections and provides reliable photometry to a few magnitudes deeper than the GALEX pipeline catalog. This method is free from source confusion over the UV magnitude range studied here; we estimate that the GALEX pipeline catalogs are confusion limited at NUV ∼ 23 and FUV ∼ 24. We have measured the UV field galaxy counts using our catalog and report a ∼50% (30%) excess of counts across FUV = 22–23.5 (NUV = 21.5–23) relative to other GALEX studies. Our number counts are a better match to deeper UV galaxy counts measured with Hubble Space Telescope.
Cycle Double Cover Conjecture

In this paper, a proof of the cycle double cover conjecture is presented. The cycle double cover conjecture purports that if a graph is bridgeless, then there exists a list of cycles in the graph such that every edge in the graph appears in the list exactly twice. By applying induction on the number of edges in a bridgeless graph, I show that when an edge is added to a bridgeless graph, we can reform the cycle double cover to include that edge. By mathematical induction, this concludes the general CDC.
Winding Overvoltage Characteristic Analysis of Modular Cascade Isolating Energy Supply Transformer of ±500 kV Hybrid HVDC Breaker

The 500 kV isolating energy supply transformer (HIET) with a modular cascade structure can serve as electrical power supply for ±500 kV hybrid HVDC breaker with high voltage isolating capability. Due to the mutual influence of HIET's stray capacitance, winding overvoltage (the overvoltage between the winding terminals) is induced by external overvoltage from HDCB, which significantly impacts on winding insulation design. In this paper, equivalent circuit models of 500 kV HIET are established. The circuit parameters extracting method is given, and circuit parameters are extracted. The winding voltage stress characteristics under lightning/switching impulse overvoltage and HDCB breaking overvoltage are analyzed. The simulation results show that the steeper the applied voltage wavefront, the greater the winding voltage stress peak. It is concluded that the stray capacitance uneven distribution of the winding terminals to ground has a significant impact on the winding voltage peak. By the 500 kV HIET prototype, the windings voltage stress characteristics are verified. The study provides a basis for the winding inter-turn insulation design, supporting the development of 500 kV HIET. It has been successfully applied and verified in Zhangbei ±500 kV DC Grid Project.
Three-dimensional electromagnetic modeling of practical superconductors for power applications

HTS are feasible for hight power applications because of the smaller consumption demand of the cooling system in comparison to the whole power device. Real industral devices contain superconductors with 2D and 3D geometry (coated conductors tapes represent an example of 2D geometry, since the superconducting layer is very thin). In order to know the feasibility and the optimum design of a certain device, there is a need of software tools. These Numerical tools have hight requirements like fast computation, a physical model for any E(J) relation of the superconductor and any complex geometry such as coils, motors and generators, where E is the electric field and J is the current density. In this work we present a 3D variational model based on a functional that restricts the problem in the superconductor volume. We show the magnetization process of a thin film and a 3D bulk sample. We compare our model of the thin film geometry with the thin film formula, reaching a good agreement. We also compare a striated tape, where the filaments are connected by linear material, with a FEM model. We present several results for a thin film with constant critical current density, Jc, magnetic-field dependent Jc, and an anisotropic E(J) relation. For the latter, E is not parallel to J when the magnetic flux density is not perpendicular to J (force free situation). The last studied situation is the 3D cubic sample. We find the time dependence of the current density and AC loss for each situation. In the cubic bulk sample, we found a non-negligible component of the current density in the direction of the applied field. The presented numerical method is very promising for 3D modeling of superconducting samples and power applications.
Is Fault-Tolerant Quantum Computation Really Possible?

The so-called "threshold" theorem says that, once the error rate per qubit per gate is below a certain value, indefinitely long quantum computation becomes feasible, even if all of the qubits involved are subject to relaxation processes, and all the manipulations with qubits are not exact. The purpose of this article, intended for physicists, is to outline the ideas of quantum error correction and to take a look at the proposed technical instruction for fault-tolerant quantum computation. It seems that the mathematics behind the threshold theorem is somewhat detached from the physical reality, and that some ideal elements are always present in the construction. This raises serious doubts about the possibility of large scale quantum computations, even as a matter of principle.
Sex-Biased Expression of Olfaction-Related Genes in the Antennae of Apis cerana (Hymenoptera: Apidae)

The olfactory system is essential for honeybees to adapt to complex and ever-changing environments and maintain cohesiveness. The Eastern honeybee Apis cerana is native to Asia and has a long history of managed beekeeping in China. In this study, we analysed the antennal transcriptomes of A. cerana workers and drones using Illumina sequencing. A total of 5262 differentially expressed genes (DEGs) (fold change > 2) were identified between these two castes, with 2359 upregulated and 2903 downregulated in drones compared with workers. We identified 242 candidate olfaction-related genes, including 15 odourant-binding proteins (OBPs), 5 chemosensory proteins (CSPs), 110 odourant receptors (ORs), 9 gustatory receptors (GRs), 8 ionotropic receptors (IRs), 2 sensory neuron membrane proteins (SNMPs) and 93 putative odourant-degrading enzymes (ODEs). More olfaction-related genes have worker-biased expression than drone-biased expression, with 26 genes being highly expressed in workers’ antennae and only 8 genes being highly expressed in drones’ antennae (FPKM > 30). Using real-time quantitative PCR (RT-qPCR), we verified the reliability of differential genes inferred by transcriptomics and compared the expression profiles of 6 ORs (AcOR10, AcOR11, AcOR13, AcOR18, AcOR79 and AcOR170) between workers and drones. These ORs were expressed at significantly higher levels in the antennae than in other tissues (p < 0.01). There were clear variations in the expression levels of all 6 ORs between differently aged workers and drones. The relative expression levels of AcOR10, AcOR11, AcOR13, AcOR18 and AcOR79 reached a high peak in 15-day-old drones. These results will contribute to future research on the olfaction mechanism of A. cerana and will help to better reveal the odourant reception variations between different biological castes of honeybees.
Lokale Algebren und Operatorprodukte am Punkt

Quantum fields are known to be singular objects; in particular, their products at coinciding space-time points are ill-defined and lead to divergences. We present a model-independent and mathematically consistent method of analysing this singular behaviour. Starting from a quantum field theory defined in terms of observables localized in finite space-time regions, we investigate its short distance structure, assuming a natural phase space condition. This leads us to precise information on the theory's field content as well as to a rigorous version of the operator product expansion. Zimmermann's normal products and a notion of non-linear local field equations are discussed in this context.
Swift monitoring of the central X‐ray source in RCW 103

The X-ray source 1E 161348-5055 lies at the centre of the 2-kyr-old supernova remnant RCW 103. Owing to its 24-ks modulation, orders-of-magnitude flux variability over a few months/years and lack of an obvious optical counterpart, IE 161348-5055 defies assignment to any known class of X-ray sources. Starting from 2006 April, Swift observed 1E 161348-5055 with its X-Ray Telescope for ∼2ks approximately once per month. During the five years covered, the source has remained in a quiescent state, with an average observed flux of ∼1.7 x 10 ―12 erg cm ―2 s ―1 (1-10keV),∼20 times lower than the historical maximum attained in its 1999-2000 outburst. The long time-span of the Swift data allows us to obtain an accurate measure of the period of IE 161348-5055 [P = 24030.42(2) s] and to derive the first upper limit on its period derivative (|P| < 1.6 × 10 ―9 s s ―1 at 3σ).
Shear Viscosity to Entropy Density Ratio in Higher Derivative Gravity with Momentum Dissipation

We investigate $\eta/s$ in linear scalar fields modified Gauss-Bonnet theory that breaks translation invariance. We first calculate $\eta/s$ both analytically and numerically and show its relationship with temperature in log-log plot. Our results show that $\eta/s\sim T^2$ at low temperatures. The causality is also considered in this work. We then find that causality violation still happens in the presence of the linear scalar field and we suggest there is a Gauss-Bonnet coupling dependent lower limit for the effective mass of the graviton. If the effective mass of the graviton is big enough, then there will be no causality violation and hence no constraints for the Gauss-Bonnet coupling.
Metrological Applications of Optical Reflectometry: A Review

This paper describes the state-of-art features of special optical fibers and integrated-optical circuits distributed parameters study by methods of optical reflectometry. Attention is paid to the study of the internal structure of fibers that preserve the polarization of the introduced radiation, active optical fibers, and waveguides inside the integrated chips, optical circuits, and other technological created media.
Epidemiology and bacterial characteristics of invasive group B streptococcus disease: a population-based study in Japan in 2010–2020

Abstract This is the first report on a population-based prospective study of invasive group B streptococcus (GBS) disease among children aged <15 years conducted over a period of 11 years in Japan. This study investigated the incidence and clinical manifestations of invasive GBS disease in children in Chiba Prefecture, Japan, and analysed the serotypes and drug susceptibility of GBS strains isolated during the study period. Overall, 127 episodes of invasive GBS disease were reported in 123 patients. Of these, 124 were observed in 120 patients aged <1 year, and the remaining three episodes were reported in a 9-year-old child and two 14-year-old children with underlying disease. For patients aged <1 year, the incidence rate per 1000 live births was 0.24 (0.15–0.36). The incidences of early-onset disease and late-onset disease were 0.04 (0.0–0.09) and 0.17 (0.08–0.25), respectively. The rate of meningitis was 45.2%, and the incidence of GBS meningitis was higher than that of other invasive diseases among children in Japan. Of the 109 patients for whom prognosis was available, 7 (6.4%) died and 21 (19.3%) had sequelae. In total, 68 strains were analysed. The most common were serotype III strains (n = 42, 61.8%), especially serotype III/ST17 strains (n = 22, 32.4%). This study showed that the incidence of invasive GBS disease among Japanese children was constant during the study period. Because of the high incidence of meningitis and disease burden, new preventive strategies, such as GBS vaccine, are essential.
Effects of Six Weeks of Hypoxia Exposure on Hepatic Fatty Acid Metabolism in ApoE Knockout Mice Fed a High-Fat Diet

Nonalcoholic fatty liver disease (NAFLD) is the most common liver disease with a characteristic of abnormal lipid metabolism. In the present study, we employed apolipoprotein E knockout (ApoE KO) mice to investigate the effects of hypoxia exposure on hepatic fatty acid metabolism and to test whether a high-fat diet (HFD) would suppress the beneficial effect caused by hypoxia treatment. ApoE KO mice were fed a HFD for 12 weeks, and then were forwarded into a six-week experiment with four groups: HFD + normoxia, normal diet (ND) + normoxia, HFD + hypoxia exposure (HE), and ND + HE. The C57BL/6J wild type (WT) mice were fed a ND for 18 weeks as the baseline control. The hypoxia exposure was performed in daytime with normobaric hypoxia (11.2% oxygen, 1 h per time, three times per week). Body weight, food and energy intake, plasma lipid profiles, hepatic lipid contents, plasma alanine aminotransferase (ALT) and aspartate aminotransferase (AST), and molecular/biochemical makers and regulators of the fatty acid synthesis and oxidation in the liver were measured at the end of interventions. Six weeks of hypoxia exposure decreased plasma triglycerides (TG), total cholesterol (TC), and low-density lipoprotein cholesterol (LDL-C) contents but did not change hepatic TG and non-esterified fatty acid (NEFA) levels in ApoE KO mice fed a HFD or ND. Furthermore, hypoxia exposure decreased the mRNA expression of Fasn, Scd1, and Srebp-1c significantly in the HFD + HE group compared with those in the HFD + normoxia group; after replacing a HFD with a ND, hypoxia treatment achieved more significant changes in the measured variables. In addition, the protein expression of HIF-1α was increased only in the ND + HE group but not in the HFD + HE group. Even though hypoxia exposure did not affect hepatic TG and NEFA levels, at the genetic level, the intervention had significant effects on hepatic metabolic indices of fatty acid synthesis, especially in the ND + HE group, while HFD suppressed the beneficial effect of hypoxia on hepatic lipid metabolism in male ApoE KO mice. The dietary intervention of shifting HFD to ND could be more effective in reducing hepatic lipid accumulation than hypoxia intervention.
Accelerability vs. Scalability: R&D Investment Under Financial Constraints and Competition

I develop a continuous-time model to examine how the interaction between competition and financial constraints affects firms’ research and development (R&D) strategies. The model integrates two key characteristics of R&D investment: accelerability (i.e., higher R&D intensity leads to faster discovery) and scalability (i.e., higher R&D intensity leads to higher project payoff). I find that firms react strategically to their rivals’ financial constraints when making investment decisions in a duopoly R&D race. In particular, firms respond positively to the R&D intensity of an unconstrained rival, while they respond in a hump-shaped fashion to the R&D intensity of a constrained rival. As a result, a constrained firm can pre-empt an unconstrained competitor in market equilibrium. Accelerability is necessary for such pre-emption to occur, and scalability generally reduces its likelihood. Comparison with a monopoly benchmark shows that the economic mechanism differs from over-investment induced by financial constraints alone. The model also generates new implications regarding how project characteristics and cash flow risks impact R&D decisions. This paper was accepted by Gustavo Manso, finance.
Opportunities for Creativity in Beginning Band Method Books

Method books serve as a key curricular resource in beginning band classrooms. Previous examinations of beginning band method books focused primarily on performance technique and pedagogy; however, a curriculum with a singular emphasis on performance will not meet all elements of the 2014 National Core Arts Standards. Therefore, we analyzed 16 beginning band method books for exercises that included creative activities such as compose, arrange, and improvise. Results indicated that 2.53% (n = 66) of the total exercises (N = 2,612) contained creative activities. The most frequently identified creative activity instruction type was improvise (n = 31, 44.93%), followed by compose (n = 27, 39.13%), and arrange (n = 11, 15.94%). These data provide insight into the degree to which beginning band method books contain exercises that include creative activities, specific activity types, and instructional directives, and may support inservice music educators and fine arts administrators in selecting method books.