Miracle-dz/UniFAR-FTUs huggingface dataset:
A novel approach for re-authentication protocol using personalized information

Since authentication is the key to access control security in Internet access for every user, therefore, how to verify a user is who he claimed to be is a very important requirement in Internet security. In some situations, users need to be re-authenticated to make sure that they are still actively engaged in real time interaction. For instance, people will be notified to dial to a specific server phone number to reconfirm his identity again before re-login using their account ID and passwords pairs. This approach has been adopted by many online game servers. In this paper, we proposed a novel approach for re-authentication protocol using personalized information with CAPTCHA.
Exploring Remote Monitoring of Degraded Compression and Bolted Joints in HV Power Transmission Lines

In this work preliminary yet comprehensive considerations are reported on the possibility for remote monitoring of degraded compression and bolted joints on high voltage overhead power lines. Measurements are performed on new, naturally aged, and artificially degraded joints to quantify the impedance discontinuity introduced along typical HV overhead lines. Numerical simulations, a preliminary time domain reflectometry (TDR) measurement campaign, and circuit simulations are performed on a real power line to study the TDR-based capabilities for the identification of the investigated joint impedances. This study sets the basic concepts to the development of a remote monitoring system for quantifying and locating degraded joints.
A Functional Coverage Metric for Estimating the Gate-Level Fault Coverage of Functional Tests

When functional tests are used for manufacturing testing, their quality for detecting manufacturing defects needs to be evaluated. Evaluating functional tests using a traditional gate-level fault simulation environment has several disadvantages. To alleviate them, we describe a functional level coverage metric for estimating gate-level fault coverage that has a high degree of correlation to gate-level coverage. We borrow concepts from simulation-based design verification by defining fault detection conditions as coverage objects and monitoring their occurrence, also called their hit counts, during RTL simulation. To reduce the simulation overhead, we abstract gate-level fault detection conditions to the architectural level. The resulting hit counts are converted to an estimated fault coverage using a formula. Experimental results are presented on three datapath modules in a high-performance microprocessor considering two applications: identification of functional tests with high gate-level coverage relative to other tests, and identification of modules or module functions that require additional functional tests
Spinal Anaesthesia with Hyperbaric Prilocaine in Day-Case Perianal Surgery: Randomised Controlled Trial

Background. The local anaesthetics used in day-case spinal anaesthesia should provide short recovery times. We aimed to compare hyperbaric prilocaine and bupivacaine in terms of sensory block resolution and time to home readiness in day-case spinal anaesthesia. Methods. Fifty patients undergoing perianal surgery were randomized into two groups. The bupivacaine-fentanyl group (Group B) received 7.5 mg, 0.5% hyperbaric bupivacaine + 20 μg fentanyl in total 1.9 mL. The prilocaine-fentanyl group (Group P) received 30 mg, 0.5% hyperbaric prilocaine + 20 μg fentanyl in the same volume. Results. Time to L1 block and maximum block was shorter in Group P than in Group B (Group P 4.6 ± 1.3 min versus Group B 5.9 ± 01.9 min, P = 0.017, and Group P 13.2 ± 7.5 min versus Group B 15.3 ± 6.6 min, P = 0.04). The time to L1 regression and S3 regression of the sensorial block was significantly shorter in Group P than in Group B (45.7 ± 21.9 min versus 59.7 ± 20.9 min, P = 0.024, and 133.8 ± 41.4 min versus 200.4 ± 64.8 min, P < 0.001). The mean time to home readiness was shorter for Group P than for Group B (155 ± 100.2 min versus 207.2 ± 62.7 min (P < 0.001)). Conclusion. Day-case spinal anaesthesia with hyperbaric prilocaine + fentanyl is superior to hyperbaric bupivacaine in terms of earlier sensory block resolution and home readiness and the surgical conditions are comparable for perianal surgery.
Health Care Providers' Liability Exposure for Inappropriate Pain Management

Recent studies have exposed the startling inadequacy of health care providers knowledge about and practice of effective pain management. For example, in one study, it was reported that 79 percent of a random sample of 454 medical-surgical inpatients experienced pain during hospitalization, and that 58 percent of patients with pain considered the pain horrible or excruciating. In another study, 67 percent of 2,415 randomly selected hospitalized patients had pain during the twenty-four hours prior to being interviewed, and 50 percent reported pain at the time of the interview. In a study of seriously ill hospitalized patients reported in 1996, half of the patients complained of pain, and one-sixth reported that they experienced extremely severe pain at least half the time. According to one literature review, 75 percent of cancer patients have reported suffering pain, and one study estimates that 25 percent of cancer patients die with severe unrelieved pain. Chronic nonmalignant pain has been described as an extremely prevalent problem, and over two-thirds of nursing home residents experience serious pain.
Polymorphism in the CETP Gene Region, HDL Cholesterol, and Risk of Future Myocardial Infarction: Genomewide Analysis Among 18 245 Initially Healthy Women From the Women’s Genome Health Study

Background—Recent trial data have challenged the hypothesis that cholesteryl ester transfer protein (CETP) and high-density lipoprotein cholesterol (HDL-C) have causal roles in atherothrombosis. One method to evaluate this issue is to examine whether polymorphisms in the CETP gene that impact on HDL-C levels also impact on the future development of myocardial infarction. Methods and Results—In a prospective cohort of 18 245 initially healthy American women, we examined over 350 000 singe-nucleotide polymorphisms (SNPs) first to identify loci associated with HDL-C and then to evaluate whether significant SNPs within these loci also impact on rates of incident myocardial infarction during an average 10-year follow-up period. Nine loci on 9 chromosomes had 1 or more SNPs associated with HDL-C at genome-wide statistical significance (P<5×10−8). However, only SNPs near or in the CETP gene at 16q13 were associated with both HDL-C and risk of incident myocardial infarction (198 events). For example, SNP rs708272 in the CETP gene was associated with a per-allele increase in HDL-C levels of 3.1 mg/dL and a concordant 24% lower risk of future myocardial infarction (age-adjusted hazard ratio, 0.76; 95% CI, 0.62 to 0.94), consistent with recent meta-analysis. Independent and again concordant effects on HDL-C and incident myocardial infarction were also observed at the CETP locus for rs4329913 and rs7202364. Adjustment for HDL-C attenuated but did not eliminate these effects. Conclusion—In this prospective cohort of initially healthy women, SNPs at the CETP locus impact on future risk of myocardial infarction, supporting a causal role for CETP in atherothrombosis, possibly through an HDL-C mediated pathway.
Fixed Boundaries Influence in Biological Networks: From Theory to Application

The purpose of this paper is to present some results about the influence of fixed boundary conditions in biological regulation networks. More precisely, we will present theoretical and simulation results in the context of theoretical connected regulation networks on Z. These results will show under which conditions phase transitions emerge from the asymptotic behaviour of such networks when they are subjected to the influence of fixed boundaries. Furthermore, we will expose some mathematical results obtained on the regulation network of the floral morphogenesis of the plant Arabidopsis thaliana that explain experimental results on the necessary presence of a Gibberellin hormone for the plant to develop normally.
Immunotargeting of catalase to ACE or ICAM-1 protects perfused rat lungs against oxidative stress

ELENA N. ATOCHINA,1 IRINA V. BALYASNIKOVA,1 SERGEI M. DANILOV,2 D. NEIL GRANGER,3 ARON B. FISHER,1 AND VLADIMIR R. MUZYKANTOV1,4 1Institute for Environmental Medicine and 4Department of Pharmacology, University of Pennsylvania, Philadelphia, Pennsylvania 19104-6068; 2Departments of Anesthesiology and Pharmacology, University of Illinois at Chicago, Chicago, Illinois 60612; and 3Department of Physiology and Biophysics, Louisiana State University Medical Center, Shreveport, Louisiana 39532
Melanoma Cells Present a MAGE-3 Epitope to CD4+ Cytotoxic T Cells in Association with Histocompatibility Leukocyte Antigen DR11

In this study we used TEPITOPE, a new epitope prediction software, to identify sequence segments on the MAGE-3 protein with promiscuous binding to histocompatibility leukocyte antigen (HLA)-DR molecules. Synthetic peptides corresponding to the identified sequences were synthesized and used to propagate CD4+ T cells from the blood of a healthy donor. CD4+ T cells strongly recognized MAGE-3281–295 and, to a lesser extent, MAGE-3141–155 and MAGE-3146–160. Moreover, CD4+ T cells proliferated in the presence of recombinant MAGE-3 after processing and presentation by autologous antigen presenting cells, demonstrating that the MAGE-3 epitopes recognized are naturally processed. CD4+ T cells, mostly of the T helper 1 type, showed specific lytic activity against HLA-DR11/MAGE-3–positive melanoma cells. Cold target inhibition experiments demonstrated indeed that the CD4+ T cells recognized MAGE-3281–295 in association with HLA-DR11 on melanoma cells. This is the first evidence that a tumor-specific shared antigen forms CD4+ T cell epitopes. Furthermore, we validated the use of algorithms for the prediction of promiscuous CD4+ T cell epitopes, thus opening the possibility of wide application to other tumor-associated antigens. These results have direct implications for cancer immunotherapy in the design of peptide-based vaccines with tumor-specific CD4+ T cell epitopes.
AN ANALYSIS OF A TRIPLET EXCITON MODEL FOR THE DELAYED LIGHT IN CHLORELLA *

Abstract— The time dependence of the delayed light in the green alga Chlorella pyrenoidosa has been examined quantitatively in the 1 to 12 msec range after excitation with light pulses (A = 6328 Å) of 100 μsec and 4.5 msec duration. We have confirmed the data of Tollin, Ruby, and Bertsch et al., on the time course of the delayed light in the msec range. New experiments, with 100 μsec flash excitation, on the time dependence of the delayed light emitted by Chlorella treated with 3‐(3,4‐dichlorophenyl)‐1,1‐dimethylurea (DMU), hydroxylamine, methyl violgen, and various combinations of these chemicals are presented. Also, data on the dependence of the delayed light intensity on the intensity of the excitation light in the 1.5 and 5.0 msec range are reported. The square law dependence, reported by Jones, in the 140 and 250 msec range is confirmed in the 1.5 and 5.0 msec range at very low light levels.
Is “Shannon-capacity of noisy computing” zero?

Towards understanding energy requirements for computation with noisy gates, we consider the computation of an arbitrary k-input, k-output binary invertible function. For broader applicability of our results, we allow using some noiseless gates in conjugation with noisy ones. However, we stipulate that the input gates on the computation graph must be separated from the output nodes by a “noisy cut. ” We show that for the “information-friction” model proposed recently for energy consumed in circuits, and for binary-input AWGN noise in the computational nodes (with fixed communication schedule), the total (gate + info-friction) energy consumption for reliable computation must diverge to infinity as the target error probability is lowered to zero. Thus, in this model, the capacity of noisy computing is zero regardless of how “rate” of computation is defined: the required energy is unbounded for reliable computation regardless of how efficiently the available resources (e.g. gates, wires, etc.) are used.
COMPUTATINAL MATERIAL MODELING OF HYDRATED CEMENT PASTE CALCIUM SILICATE HYDRATE ( CSH ) CHEMISTRY STRUCTURE –-INFLUENCE OF MAGNESIUM ION EXCHANGE ON MECHANICAL STIFFNESS : CSH JENNITE

Computational Material Modeling of Hydrated Cement Paste Calcium Silicate Hydrate (C-S-H) Chemistry Structure Influence of Magnesium Exchange on Mechanical Stiffness: C-S-H Jennite Report Title Cementitious materials have material, geometric features ranging from molecular/nano, micro-, mesoand macro scales. Features and changes in material chemistry/nano scale influence the hydration process, formed micro scale morphology, associated properties and behavior at engineering length scales. In the present paper, effect of material ion exchange on mechanical stiffness properties of nano level hydrated cement paste constituent calcium silicate hydrate (C-S-H) based on its material chemistry structure are studied following a molecular dynamics (MD) computational modeling methodology. Calcium ions are replaced with Magnesium ions in traditional C-S-H Jennite crystal structure of the hydrated cement constituent. Traditional C-S-H Jennite structure, and Magnesium modified structures obtained by calcium exchange of magnesium are used in the MD based material modeling analysis. Extensive modeling analysis established optimal computational MD modeling parameters and molecular material sizes employed. The present study clearly shows the influence of material chemistry due to Magnesium ion exchange in CSH-Jennite with predicted elastic modulus that changes with the level of Magnesium in CSH-Jennite material chemistry structure. Conference Name: 1st Pan-American Conference on Computational Mechanics Conference Date: April 27, 2015 1 Pan-American Congress on Computational Mechanics – PANACM 2015 XI Argentine Congress on Computational Mechanics – MECOM 2015 S. Idelsohn, V. Sonzogni, A. Coutinho, M. Cruchaga, A. Lew & M. Cerrolaza (Eds) COMPUTATINAL MATERIAL MODELING OF HYDRATED CEMENT PASTE CALCIUM SILICATE HYDRATE (C-S-H) CHEMISTRY STRUCTURE –INFLUENCE OF MAGNESIUM ION EXCHANGE ON MECHANICAL STIFFNESS: C-S-H JENNITE RAM V. MOHAN1, WAYNE D. HODO2, BABATUNDE ADEBIYI, JOHN RIVAS, AND AHMED MOHAMED 1Department of Nanoengineering, North Carolina A&T State University 2907 E Lee Street, Greensboro, NC 27401, USA rvmohan@ncat.edu; http://jsnn.ncat. uncg.edu 2U. S. Army Engineer and Research Development Center 3907 Halls Ferry Road, Vicksburg, MS 39180, USA Wayne.D. Hodo@usace.army. mil; http://www.erdc. usace.army. mil
Financial Development and Economic Growth in China

The purpose of this paper is to examine the relationship between financial development and economic growth. In particular, the authors examine the impact of financial development on the growth of primary, secondary, and tertiary industries in China. Ordinary Least Square (OLS) multiple regressions are applied on a set of data from China for the period 1978 to 2013 to determine the effects of financial development on economic growth, while controlling for other macroeconomic variables, namely labor force, capital growth, inflation rate and export growth. The empirical results show that financial development has a negative effect on economic growth in general, but on the growth of the tertiary industry in particular. By contrast, it is found that financial development has no significant effect on the primary and secondary industries. The findings offer policymakers some useful insights that more attention may need to be paid on developing capital markets and providing more investment choices/opportunities for Chinese households. This paper is different from most of the previous studies as it uses up-to-date data (1978-2013) from China capturing the effects of financial development on economic growth in addition to other macroeconomic factors.
Geo-Conquesting Based on Graph Analysis for Crowdsourced Metatrails from Mobile Sensing

This article investigates graph analysis for intelligent marketing in smart cities, where metatrails are crowdsourced by mobile sensing for marketing strategies. Unlike most works that focus on client sides, this study is intended for market planning, from the perspective of enterprises. Several novel crowdsourced features based on metatrails, including hotspot networks, crowd transitions, affinity subnetworks, and sequential visiting patterns, are discussed in the article. These smart footprints can reflect crowd preferences and the topology of a site of interest. Marketers can utilize such information for commercial resource planning and deployment. Simulations were conducted to demonstrate the performance. At the end, this study also discusses different scenarios for practical geo-conquesting applications.
Soft biometrics systems: Reliability and asymptotic bounds

This work presents a preliminary statistical analysis on the reliability of soft biometrics systems which employ multiple traits for human identification. The analysis places emphasis on the setting where identification errors occur mainly due to cross-subject interference, i.e., due to the event that subjects share similar facial and body characteristics. Finally asymptotic analysis provides bounds which insightfully interpret this statistical behavior.
Correlates of Sedentary Time and Physical Activity Among Preschool-Aged Children

Introduction Few studies have examined the correlates of objectively measured amounts of sedentary time and physical activity in young children. We evaluated the demographic, biological, behavioral, social, and environmental correlates of the amount of sedentary time and moderate-to-vigorous physical activity (MVPA) as measured by accelerometry in preschool-aged children. Methods We obtained baseline measurements of physical activity by using an Actical accelerometer among 337 preschool-aged children (aged 2-5) of overweight or obese mothers. For children, we defined sedentary time as less than 12 counts per 15 seconds and MVPA as 715 or more counts per 15 seconds. Body mass index of the mother and child (calculated from measured height and weight) and maternal physical activity as measured by accelerometer were included as potential correlates. Mothers self-reported all other potential correlates. We used multivariable linear regression analyses to examine correlates of the amount of sedentary time and MVPA. Results Children had an average of 6.1 hours per day of sedentary time and 14.9 minutes per day of MVPA. In multivariable analysis, boys (P <.001) had fewer minutes per day of sedentary time, whereas older children (P <.001), boys (P <.001), children in high-income households (>$60,000/y [P = .005]), and children who spent more time outdoors (P = .001) had more MVPA. Conclusion Both modifiable and nonmodifiable factors were correlated with preschool children's amount of MVPA, which can be helpful when designing interventions for this age group. The lack of correlates for sedentary time indicates the need for further investigation into this behavior.
Effects of a 20-month cluster randomised controlled school-based intervention trial on BMI of school-aged boys and girls: the HEIA study

Background School-based interventions that target prevention of overweight and obesity in children have been tested with mixed results. Thus, successful interventions are still called for. The aim of the present study was to investigate effects of a multicomponent school-based intervention programme targeting physical activity, sedentary and dietary behaviours on anthropometric outcomes. Methods A 20-month intervention was evaluated in a cluster randomised, controlled study of 1324 11-year-olds. Outcome variables were body mass index (BMI), BMI-for-age z-score (BMIz), waist circumference (WC), waist-to-height ratio (WTHR) and weight status (International Obesity Task Force's cut-offs). Weight, height and WC were measured objectively; pubertal status was self-reported and parental education was self-reported by the parents. Intervention effects were determined by one-way analysis of covariance and logistic regression, after checking for clustering effects of school, and moderating effects of gender, pubertal status and parental education. Results Beneficial effects were found for BMI (p=0.02) and BMIz (p=0.003) in girls, but not in boys. While a beneficial effect was found for BMI (p=0.03) in participants of parents reporting a high level of education, a negative effect was found for WTHR in participants with parents reporting a low level of education (p=0.003). There were no intervention effects for WC and weight status. Conclusions A multicomponent 20-month school-based intervention had a beneficial effect on BMI and BMIz in adolescent girls, but not in boys. Furthermore, children of higher educated parents seemed to benefit more from the intervention, and this needs attention in future interventions to avoid further increase in social inequalities in overweight and obesity.
Physical activity to prevent cardiovascular disease. How much is enough?

OBJECTIVE To review the role of physical activity in primary prevention of cardiovascular (CV) diseases with particular attention to the intensity and amount of physical activity needed to benefit health. QUALITY OF EVIDENCE MEDLINE was searched for articles published in the indexed English literature from January 1991 to December 2000 using key words related to physical activity (e.g., exercise, physical fitness), CV and coronary artery disease (CAD) risk factors (e.g., diabetes, hypertension, hyperlipidemia, obesity). Findings were supplemented by consensus documents and other published literature. Most articles described prospective observational studies. MAIN MESSAGE Clear evidence indicates an inverse linear dose response between amount of physical activity and all-cause mortality, total CV disease, and CAD incidence and mortality. The minimal effective dose is unclear, but physical activity that results in energy expenditure of approximately 4200 kJ.week-1 appears to be associated with substantial benefits. Physical activity need not be vigorous to benefit health. CONCLUSION Moderate activity, such as brisk walking for 30 to 60 minutes a day most days of the week, is associated with significant reductions in the incidence and mortality of CV disease.