Miracle-dz/UniFAR-FTUs huggingface dataset:
Smart indoor positioning using BLE technology

One of the prime challenges in indoor positioning is to determine the location of users inside the building. Many technologies have been used for indoor positioning system but requirement is low cost, energy efficient and stable technology. To fulfil this requirement, Bluetooth low energy(BLE) tags are used due to its low cost and energy efficiency for positioning of user in the indoor building. Our approach is deployment of BLE tags on the ceiling of rooms and Received Signal Strength Indicator (RSSI) of tags is calculated. When any smart phone enters within the range of BLE tags which are already deployed in the rooms, the tag with high received signal strength will be nominated and information of that tag along with the information of user will be uploaded to the Web server. And user can see its own location from his smart phone. In this way, it's easy to locate the user inside the building. This method is easy to implement due to its low complexity. In this paper, the department of Telecommunication MUET Jamshoro is used as case study and tracked the working staff within the department.
A Low-cost 60 GHz OFDM modem

A simple soft-demapping scheme for Rectangular Quadrature Amplitude Modulation (R-QAM) signals is developed for a low-cost 60 GHz OFDM baseband chip design, conforming to the IEEE802.15. 3C standard. The scheme is equally applicable to a generic bit-interleaved Orthogonal Frequency Division Multiplexing (OFDM) modulation for both square QAM (S-QAM) and R-QAM constellations. The channel coding employs the concatenation of convolutional and Reed-Solomon (RS) codes. Simulation shows that this simple soft-demapping scheme effectively achieves the same performance of an optimum log-likelihood ratio (LLR) demapper. The exact formula for the difference between the proposed approximate LLR and the optimum LLR is derived.
Associations between overweight and obesity with bullying behaviors in school-aged children.

OBJECTIVE The prevalence of overweight and obesity in children is rising. Childhood obesity is associated with many negative social and psychological ramifications such as peer aggression. However, the relationship between overweight and obesity status with different forms of bullying behaviors remains unclear. The purpose of this article is to examine these relationships. METHODS We examined associations between bullying behaviors (physical, verbal, relational, and sexual harassment) with overweight and obesity status in a representative sample of 5749 boys and girls (11-16 years old). The results were based on the Canadian records from the 2001/2002 World Health Organization Health Behaviour in School-Aged Children Survey. Body mass index (BMI) and bullying behaviors were determined from self-reports. RESULTS With the exception of 15- to 16-year-old boys, relationships were observed between BMI category and peer victimization, such that overweight and obese youth were at greater relative odds of being victims of aggression than normal-weight youth. Strong and significant associations were seen for relational (eg, withdrawing friendship or spreading rumors or lies) and overt (eg, name-calling or teasing or hitting, kicking, or pushing) victimization but not for sexual harassment. Independent of gender, there were no associations between BMI category and bully-perpetrating in 11- to 14-year-olds. However, there were relationships between BMI category and bully-perpetrating in 15- to 16-year-old boys and girls such that the overweight and obese 15- to 16-year-olds were more likely to perpetrate bullying than their normal-weight classmates. Associations were seen for relational (boys only) and overt (both genders) forms of bully-perpetrating but not for sexual harassment. CONCLUSIONS Overweight and obese school-aged children are more likely to be the victims and perpetrators of bullying behaviors than their normal-weight peers. These tendencies may hinder the short- and long-term social and psychological development of overweight and obese youth.
Scope-Aware Useful Cache Block Analysis for Data Cache Related Preemption Delay

Static timing analysis is crucial for design of realtime systems. While the worst-case execution time of a task is typically computed or measured in a single task environment, the presence of caches imposes additional cache related preemption delay (CRPD) cost to the lower priority tasks in a preemptive multi-tasking system. In this work, we show that existing instruction CRPD analysis techniques cannot be straightforwardly extended for safe and precise data CRPD analysis. In order to capture the dynamic behavior of the data memory references, we introduce the notion of temporal scopes into the abstract cache state (ACS) to capture the data memory blocks that must or may reside in the cache during certain time intervals of program execution. Based on the improved ACS representation, we present a temporal scope aware useful cache block (UCB) calculation for safe and tight estimation of the data CRPD cost. Experimental results show that the proposed technique leads to substantially tighter CRPD estimation, and is applicable to programs with complex data reference patterns.
Adaption of the serotoninergic neuronal phenotype in the absence of 5‐HT autoreceptors or the 5‐HT transporter: involvement of BDNF and cAMP

Serotonin 5‐HT1A and 5‐HT1B receptors and the 5‐HT transporter are key regulators of the serotoninergic neuronal phenotype. We show here that genetic deletion of any of these elements differentially regulates 5‐HT neuronal number in rostral raphe cultures from E14 mice. Serotonin neuronal number was increased by almost four‐fold and 1.8‐fold in cultures from 5‐HT1AR−/− and 5‐HT1BR−/− mice, respectively. In contrast, the lack of serotonin transporter expression was associated with a 50% decrease in 5‐HT neuronal number. In raphe cultures from the rat, BDNF and cAMP have been shown to up‐regulate the neuronal serotoninergic phenotype through TrkB‐dependent mechanisms [Rumajogee et al. (2002) J. Neurochem. , 83, 1525–1528]. Similar tyrosine kinase‐dependent up‐regulating effects, in the absence of serotoninergic key‐elements are reported here, on both 5‐HT neuronal number and neurites length. However, the extents of BDNF‐triggered and cAMP‐triggered effects on serotoninergic neuritic length were approximately 1.5‐fold higher in 5‐HT1AR−/− mutants. These findings show that the up‐regulatory mechanisms triggered by BDNF on serotoninergic neuronal number and neurite extension are different and that the latter are partially linked to 5‐HT, probably through 5‐HT1A autoreceptors. Together, these data suggest that serotonin autoreceptors, mainly 5‐HT1A but also 5‐HT1B, may be responsible for a tonic auto‐inhibitory effect of 5‐HT itself on the serotoninergic neuronal phenotype during embryonic development, particularly marked in the absence of the 5‐HT transporter.
I/O-Efficient Rectangular Segment Search

We consider the I/O-efficient rectangular segment search problem in 2D. The problem involves storing a given set ${\cal S}$ of $N$ line segments in a data structure such that an axis aligned rectangular range query ${\cal R}$ can be performed efficiently; i.e., report all line segments in ${\cal S}$ which intersect ${\cal R}$. We give a data structure requiring space $O(N(N/B)^2)$ disk blocks that can answer a range query ${\cal R}$ using $O(log_B N + K/B)$ I/Os, where $B$ is the number of line segments transferred in one I/O, and $K$ is the number of line segments intersecting ${\cal R}$. Search complexity of $O(log_B (N/B) + K/B)$ I/Os can be achieved with reduced storage if the set ${\cal S}$ contains only non-intersecting line segments, orif set ${\cal S}$ contains only horizontal and vertical line segments. In the former case the space complexity is $O((N/B)^2)$ disk blocks and in the latter case the space complexity is $O(N \frac{\log N}{\log\log_B N})$. We also consider the problem of finding all the line segments which are entirely within the rectangle ${\cal R}$ if the set ${\cal S}$ contains only vertical and horizontal line segments. For this problem, an optimal data structure is presented with size $O(N \frac{\log N}{\log\log_B N})$ disk blocks that requires $O(log_B (N/B) + K/B)$ I/Os to answer the query.
Multimodal Vision–Haptic Perception of Digital Watermarks Embedded in 3-D Meshes

In this paper, a study is conducted to investigate the role of multisensory feedback in the perception of a watermark embedded in a haptic-enabled 3-D virtual surface. Specifically, we focus on whether the use of a bimodal approach, where a subject is looking at, and touching a 3-D mesh could in fact improve the perceptibility of a watermark as opposed to when only a single modality (vision-alone or haptic-alone) is available. The experiments are performed using a vision-haptic interface that enables users to see and touch virtual objects at the same location in space. This approach enables superior integration of vision and touch than a conventional 2-D screen-based display. An analysis of variance (ANOVA) is also conducted to statistically explore the impact of the considered modalities (vision, haptic, and vision-haptic) on the measured watermark detection thresholds across different resolutions of the underlying virtual 3-D mesh. Overall, the results suggest that relying on bimodal vision-haptic feedback is better than any of the single modalities when detecting a watermark embedded in a 3-D model. In addition, it has been assessed that the impact of the selected modality on the perceptibility of the 3-D watermark is independent of the chosen surface resolution.
Discrimination of yeast genes involved in methionine and phosphate metabolism on the basis of upstream motifs

MOTIVATION In yeast, methionine and phosphate metabolism are regulated by the complexes Met4p/Met28p/Cbf1p and Pho4p, respectively. The binding sites for these factors share a common core CACGTG. We evaluate our capability to discriminate phosphate- and methionine-responding genes on the basis of putative regulatory elements, despite the similarity between Met4p/Met28p/Cbf1p and Pho4p consensus. RESULTS We scanned upstream regions of methionine, phosphate and control genes with position-specific weight matrices for Pho4p, Met4p/Met28p/Cbf1p and Met31p/Met32p, and applied discriminant analysis to classify genes according to matrix matching scores. This analysis showed that matrix scores provided a good discrimination between phosphate, methionine and control genes. The optimal parameters have then been used to predict phosphate and methionine regulation at a genome scale. The genome-scale analysis predicts 37 genes as methionine-regulated and 40 as phosphate-regulated. We compare the predictive results with high throughput data and discuss the difference. AVAILABILITY The programs for sequence retrieval and analysis, as well as the complete data and results, are available on the website on regulatory sequence analysis tools (http://rsat.scmbb.ulb.ac.be/rsat/). CONTACT jvanheld@scmbb.ulb.ac.be SUPPLEMENTARY INFORMATION The complete datasets and results are available at http://rsat.scmbb.ulb.ac.be/rsat/data/published_data/Gonze_MET_PHO/
Changes in Metabolic Profiles during Acute Kidney Injury and Recovery following Ischemia/Reperfusion

Changes of metabolism have been implicated in renal ischemia/reperfusion injury (IRI). However, a global analysis of the metabolic changes in renal IRI is lacking and the association of the changes with ischemic kidney injury and subsequent recovery are unclear. In this study, mice were subjected to 25 minutes of bilateral renal IRI followed by 2 hours to 7 days of reperfusion. Kidney injury and subsequent recovery was verified by serum creatinine and blood urea nitrogen measurements. The metabolome of plasma, kidney cortex, and medulla were profiled by the newly developed global metabolomics analysis. Renal IRI induced overall changes of the metabolome in plasma and kidney tissues. The changes started in renal cortex, followed by medulla and plasma. In addition, we identified specific metabolites that may contribute to early renal injury response, perturbed energy metabolism, impaired purine metabolism, impacted osmotic regulation and the induction of inflammation. Some metabolites, such as 3-indoxyl sulfate, were induced at the earliest time point of renal IRI, suggesting the potential of being used as diagnostic biomarkers. There was a notable switch of energy source from glucose to lipids, implicating the importance of appropriate nutrition supply during treatment. In addition, we detected the depressed polyols for osmotic regulation which may contribute to the loss of kidney function. Several pathways involved in inflammation regulation were also induced. Finally, there was a late induction of prostaglandins, suggesting their possible involvement in kidney recovery. In conclusion, this study demonstrates significant changes of metabolome kidney tissues and plasma in renal IRI. The changes in specific metabolites are associated with and may contribute to early injury, shift of energy source, inflammation, and late phase kidney recovery.
Observable Liveness

Abstract. Whereas the traditional liveness property for Petri nets guarantees that each transition can always occur again, observable liveness requires that, from any reachable marking, each observable transition can be forced to fire by choosing appropriate controllable transitions; hence it is defined for Petri nets with distinguished observable and controllable transitions. We introduce observable liveness and show this new notion generalizes liveness in the following sense: liveness of a net implies observable liveness, provided the only conflicts that can appear are between controllable transitions. This assumption refers to applications where the uncontrollable part models a deterministic machine (or several deterministic machines), whereas the user of the machine is modeled by the controllable part and can behave arbitrarily.
Security Analysis of HyRal

It is further believed that any practical attacks against HyRal are not possible with respect to the state-of-the-art. That is, we conclude that HyRal might be resistant to some well-known analysis such as differential attack, higher order differential attack, linear attack(including Truncated Linear Attack), interpolation attacks, algebraic attack (including XL attack and XSL attack), related key attack, and the existence of weak keys and semi-weak keys.
Sagittal Plane Deformity in the Thoracic Spine: A Clue to the Presence of Syringomyelia as a Cause of Scoliosis

Study Design. A retrospective review of scoliosis radiographs of 93 patients with either idiopathic scoliosis or syringomyelia-associated scoliosis were assessed, defining their sagittal alignment. Objective. To validate an observation regarding the absence of Dickson’s sagittal deformity of the thoracic spine in patients with syringomyelia-associated scoliosis. Summary of Background Data Patients with adolescent idiopathic scoliosis have a classic sagittal deformity. Dickson described that patients with adolescent idiopathic scoliosis (AIS) have an associated lordotic deformity at the apex of their coronal deformity. Materials and Methods. Retrospective reviews of standard scoliosis series radiographs of 93 patients with idiopathic or syringomyelia-associated scoliosis from two institutions were compared. Particular attention was given to the lateral radiograph of the spine assessing presence or absence of Dickson’s apical lordosis. Nine patients had to be excluded because of inadequate imaging. The study group consisted of 30 patients with scoliosis from TSRH with documented syringomyelia identified between 1985 and 1997. The demographic and radiographic features of this group were compared with those of a control group consisting of a consecutive series of 54 patients from HSS with adolescent idiopathic and normal MRI. The groups were comparable for age (mean age: control 13 y; syrinx 12 y) and curve pattern but differed in curve magnitude (mean Cobb: control 50°; syrinx 40°). Results. Apical lordosis was present in 97% of patient with AIS and a normal MRI but was absent in 75% of patients with syringomyelia-associated scoliosis (P < 0.0001). The results also confirmed that male patients with scoliosis and left-side curves have a predisposition to having a syringomyelia (P < 0.0001). Conclusions. Sagittal plane deformity in scoliosis can be an indicator of the presence of a syringomyelia. Our results reinforce the necessity of assessing sagittal plane deformity when treating scoliosis. If apical lordotic deformity is absent, a diagnosis of idiopathic scoliosis should be made with caution.
Assessment of Inflammatory Burden Contralateral to the Symptomatic Carotid Stenosis Using High-Resolution Ultrasmall, Superparamagnetic Iron Oxide–Enhanced MRI

Background and Purpose— It is well known that the vulnerable atheromatous plaque has a thin, fibrous cap and large lipid core with associated inflammation. This inflammation can be detected on MRI with use of a contrast medium, Sinerem, an ultrasmall superparamagnetic iron oxide (USPIO). Although the incidence of macrophage activity in asymptomatic disease appears low, we aimed to explore the incidence of MRI-defined inflammation in asymptomatic plaques in patients with known contralateral symptomatic disease. Methods— Twenty symptomatic patients underwent multisequence MRI before and 36 hours after USPIO infusion. Images were manually segmented into quadrants, and the signal change in each quadrant was calculated after USPIO administration. A mixed mathematical model was developed to compare the mean signal change across all quadrants in the 2 groups. Patients had a mean symptomatic stenosis of 77% compared with 46% on their asymptomatic side, as measured by conventional angiography. Results— There were 11 (55%) men, and the median age was 72 years (range, 53 to 84 years). All patients had risk factors consistent with severe atherosclerotic disease. All symptomatic carotid stenoses had inflammation, as evaluated by USPIO-enhanced imaging. On the contralateral sides, inflammatory activity was found in 19 (95%) patients. Contralaterally, there were 163 quadrants (57%) with a signal loss after USPIO when compared with 217 quadrants (71%) on the symptomatic side (P=0.007). Conclusions— This study adds weight to the argument that atherosclerosis is a truly systemic disease. It suggests that investigation of the contralateral side in patients with symptomatic carotid stenosis can demonstrate inflammation in 95% of plaques, despite a mean stenosis of only 46%. Thus, inflammatory activity may be a significant risk factor in asymptomatic disease in patients who have known contralateral symptomatic disease. Patients with symptomatic carotid disease should have their contralateral carotid artery followed up.
Reputation‐based Web service orchestration in cloud computing: A survey

Cloud computing is no longer the future but the present. Every day, more and more companies and service providers transfer their businesses and operations to the cloud, benefiting from its multiple advantages. Moreover, the flexibility offered by many cloud services allows to easily build sophisticated services by just composing simpler ones, rather than creating them from zero. Yet, to mitigate potential security threats and keep the maximum performance at any time, a smart selection of those composite services constitutes a key aspect. In this paper, we introduce the reader to the problem of Web service selection based on their reputation scores and subsequently present a survey on some of the most relevant reputation‐based Web service orchestration schemes for cloud computing in the literature. For each one of these approaches, a thorough analysis of their pros and cons has been performed, providing a comprehensive comparison amongst all of them leading to the conclusion that, to the best of our knowledge, there is no one single model elegantly fitting to each and every situation that could occur in such a dynamic environment like cloud computing. Finally, we present some current challenges and future research trends in the field of reputation‐based service orchestration in cloud computing. Copyright © 2013 John Wiley & Sons, Ltd.
Different Vaccine Vectors Delivering the Same Antigen Elicit CD8+ T Cell Responses with Distinct Clonotype and Epitope Specificity1

Prime-boost immunization with gene-based vectors has been developed to generate more effective vaccines for AIDS, malaria, and tuberculosis. Although these vectors elicit potent T cell responses, the mechanisms by which they stimulate immunity are not well understood. In this study, we show that immunization by a single gene product, HIV-1 envelope, with alternative vector combinations elicits CD8+ cells with different fine specificities and kinetics of mobilization. Vaccine-induced CD8+ T cells recognized overlapping third V region loop peptides. Unexpectedly, two anchor variants bound H-2Dd better than the native sequences, and clones with distinct specificities were elicited by alternative vectors. X-ray crystallography revealed major differences in solvent exposure of MHC-bound peptide epitopes, suggesting that processed HIV-1 envelope gave rise to MHC-I/peptide conformations recognized by distinct CD8+ T cell populations. These findings suggest that different gene-based vectors generate peptides with alternative conformations within MHC-I that elicit distinct T cell responses after vaccination.
Geometric clustering models for multimedia databases

Recently, in the elds of information retrieval, Data Mining, or Knowledge Discovery in Databases (KDD), is intensively studied to extract implicit useful information from large amount of data. One of the important objectives of KDD is to obtain generalizations by grouping similar objects via clustering. In the case of multi-media databases such as full text database and image database, geometric structure of the feature space of the objects may be used, where computational geometry may play an important role.