Miracle-dz/UniFAR-FTUs huggingface dataset:
Genome‐wide patterns of standing genetic variation in a marine population of three‐spined sticklebacks

Since the end of the Pleistocene, the three‐spined stickleback (Gasterosteus aculeatus) has repeatedly colonized and adapted to various freshwater habitats probably originating from ancestral marine populations. Standing genetic variation and the underlying genomic architecture both have been speculated to contribute to recent adaptive radiations of sticklebacks. Here, we expand on the current genomic resources of this fish by providing extensive genome‐wide variation data from six individuals from a marine (North Sea) stickleback population. Using next‐generation sequencing and a combination of paired‐end and mate‐pair libraries, we detected a wide size range of genetic variation. Among the six individuals, we found more than 7% of the genome is polymorphic, consisting of 2 599 111 SNPs, 233 464 indels and structural variation (SV) (>50 bp) such as 1054 copy‐number variable regions (deletions and duplications) and 48 inversions. Many of these polymorphisms affect gene and coding sequences. Based on SNP diversity, we determined outlier regions concordant with signatures expected under adaptive evolution. As some of these outliers overlap with pronounced regions of copy‐number variation, we propose the consideration of such SV when analysing SNP data from re‐sequencing approaches. We further discuss the value of this resource on genome‐wide variation for further investigation upon the relative contribution of standing variation on the parallel evolution of sticklebacks and the importance of the genomic architecture in adaptive radiation.
Attractivity of nonlinear impulsive delay differential equations.

The attractivity of nonlinear differential equations with time delays and impulsive effects is discussed. We obtain some criteria to determine the attracting set and attracting basin of the impulsive delay system by developing an impulsive delay differential inequality and introducing the concept of nonlinear measure. Examples and their simulations illustrate the effectiveness of the results and different asymptotical behaviors between the impulsive system and the corresponding continuous system.
3D finite element modelling and comparative performance analysis between axial and radial flux machines for micro wind turbine application

This paper presents a comparative performance analysis between the axial flux and radial flux permanent magnet synchronous machines dedicated to a 550W micro wind turbine application. Both machines are based on iron armature cores and permanent magnet structure, but one has a slotted stator and single sided rotor disc and the other one is a radial flux surface mounted inner rotor machine. This study is based on a 3D finite element modelling using the Multiphysics program ANSYS. The finite element analysis was applied for the two machines configurations in order to evaluate their performances, compare their efficiency regarding the material consumption of the active parts and eventually predict their cost. The obtained results promote the axial flux topology as the best solution for micro wind turbine application.
Automatically building a Tunisian Lexicon for Deverbal Nouns

The sociolinguistic situation in Arabic countries is characterized by diglossia (Ferguson, 1959) : whereas one variant Modern Standard Arabic (MSA) is highly codified and mainly used for written communication, other variants coexist in regular everyday’s situations (dialects). Similarly, while a number of resources and tools exist for MSA (lexica, annotated corpora, taggers, parsers . . . ), very few are available for the development of dialectal Natural Language Processing tools. Taking advantage of the closeness of MSA and its dialects, one way to solve the problem of the lack of resources for dialects consists in exploiting available MSA resources and NLP tools in order to adapt them to process dialects. This paper adopts this general framework: we propose a method to build a lexicon of deverbal nouns for Tunisian (TUN) using MSA tools and resources as starting material.
Recurrence rate of repaired hard palate oronasal fistula with conchal cartilage graft

Background: After cleft palate repair, oronasal fistula (ONF) formation is one of the considerable and troublesome complications. Conchal cartilage graft is one option that can be used in recurrent fistula correction. The aim of the current study is investigating the recurrence rate of the hard palate ONF or ONF at the junction of hard and soft palate after utilizing conchal cartilage graft and comparing this rate with other methods. Materials and Methods: In this observational prospective study, 29 patients suffering from ONF with small, medium and large sizes who were referring to Alzahra university hospital, Isfahan, Iran and Fateme Zahra university hospital, Tehran, Iran between November 2011 and November 2012 were enrolled. All patients had midline cleft palate, 29.6% of them had cleft lip too that was repaired previously. All patients were followed-up for 2 years (every 2 months) after repair. Results: The mean (range) age of studied samples was 10.7 (2-23) years. 16 patients (55.7%) were female, and reminders were male. During 2 years followup, we detected recurrence of ONF in 6 patients (20.68%) and the success rate was 79.32%. The recurrence rate, after applying the current approach, among who experienced the several times of recurrence was significantly higher than among those who experienced first time of recurrence (33.3% vs. 7.1%; P < 0.001). The mean [±SD] age of failed and successfully repaired patients were 11.3 (±4.5) and 8.4 (±5.25) years, respectively (P > 0.1). Conclusion: Using of conchal cartilage graft for recurrent ONF with ≤1 cm was safe and efficacious, in ONF >1 cm conchal cartilage graft can be used as a primary method and if recurrence occurred chooses other complex procedure.
Pydron: Semi-Automatic Parallelization for Multi-Core and the Cloud

The cloud, rack-scale computing, and multi-core are the basis for today's computing platforms. Their intrinsic parallelism is a challenge for programmers, specially in areas lacking the necessary economies of scale in application/ code reuse because of the small number of potential users and frequently changing code and data. In this paper, based on an on-going collaboration with several projects in astrophysics, we present Pydron, a system to parallelize and execute sequential Python code on a cloud, cluster, or multi-core infrastructure. While focused on scientific applications, the solution we propose is general and provides a competitive alternative to moving the development effort to application specific platforms. Pydron uses semi-automatic parallelization and can parallelize with an API of only two decorators. Pydron also supports the scheduling and run-time management of the parallel code, regardless of the target platform. First experiences with real astrophysics data pipelines indicate Pydron significantly simplifies development without sacrificing the performance gains of parallelism at the machine or cluster level.
Some Thoughts on Traditional African Idea of Management

This article examines the nature of management in Africa in the pre-colonial period. Contrary to the popular view especially in the West that ancient African societies carried out their activities without planning, there is over whelming evidence that systematic patterns were followed for positive results in pre-colonial Africa. Across the continent long before European colonialism, careful planning was carried out, and individual and collective resources were sedulously managed for the benefit of all. The various aspects of this process are discussed from a historical perspective. (The Journal of Cultural Studies: 2001 3(1): 99-107)
Use of Bacteriophage Ba1 To Identify Properties Associated with Bordetella avium Virulence

ABSTRACT Bordetella avium causes bordetellosis, an upper respiratory disease of birds. Commercially raised turkeys are particularly susceptible. We report here on the use of a recently described B. avium bacteriophage, Ba1, as a tool for investigating the effects of lysogeny and phage resistance on virulence. We found that lysogeny had no effect on any of the in vivo or in vitro measurements of virulence we employed. However, two-thirds (six of nine) spontaneous phage-resistant mutants of our virulent laboratory strain, 197N, were attenuated. Phage resistance was associated, in all cases, with an inability of the mutants to bind phage. Further tests of the mutants revealed that all had increased sensitivities to surfactants, and increased amounts of incomplete (O-antigen-deficient) lipopolysaccharide (LPS) compared to 197N. Hot phenol-water-extracted 197N LPS inactivated phage in a specific and dose-dependent manner. Acid hydrolysis and removal of lipid A had little effect upon the ability of isolated LPS to inactivate Ba1, suggesting that the core region and possibly the O antigen were required for phage binding. All of the mutants, with one exception, were significantly more sensitive to naive turkey serum and, without exception, significantly less able to bind to tracheal rings in vitro than 197N. Interestingly, the three phage-resistant mutants that remained virulent appeared to be O antigen deficient and were among the mutants that were the most serum sensitive and least able to bind turkey tracheal rings in vitro. This observation allowed us to conclude that even severe defects in tracheal ring binding and serum resistance manifested in vitro were not necessarily indicative of attenuation and that complete LPS may not be required for virulence.
Revisiting the Red Effect on Attractiveness and Sexual Receptivity: No Effect of the Color Red on Human Mate Preferences

Color-in-context theory is the first theoretical framework for understanding color effects in human mate preferences, arguing that red clothing enhances attractiveness ratings. Here we present three empirical studies failing to support this prediction. We aimed to extend the current literature by differentiating color effects by temporal context (short-term vs. long-term mating). Experiment 1 involved Dutch participants rating a woman in red, white, and black on (sexual) attractiveness. Experiment 2 replicated the first experiment with an American sample. In the final experiment, we aimed to replicate a study that did find evidence of a red effect, using a substantially larger sample size. The results from each of the three studies (totaling N = 830 men) fail to support the red effect. We discuss the implications of our results and avenues for future research on red effects and attractiveness.
Feasibility of Sentinel Lymph Node Biopsy in Breast Cancer Patients with Initial Axillary Lymph Node Metastasis after Primary Systemic Therapy

Purpose Primary systemic therapy (PST) downstages up to 40% of initial documented axillary lymph node (ALN) metastases in breast cancer. The current surgical treatment after PST consists of breast tumor resection and axillary lymph node dissection (ALND). This strategy, however, does not eliminate unnecessary ALND in patients with complete remission of axillary metastases. The aim of this study was to examine the accuracy of sentinel lymph node biopsy (SLNB) after PST among patients with documented ALN metastasis at presentation and to identify the rate of pathologic complete-remission (CR) with ALN after PST. Methods We analyzed 66 patients with ALN metastasis that was pathologically proven preoperatively who underwent SLNB and concomitant ALND after PST. Axillary ultrasound (AUS) was used to evaluate the clinical response of initially documented ALN metastasis after PST. Intraoperative lymphatic mapping was performed using blue dye with or without radioisotope. Results After PST, 34.8% of patients had clinical CR of ALN on AUS and 28.8% patients had pathologic CR of ALN. The overall success rate of SLNB after PST was 87.9%, and the sentinel lymph node identification rate in patients with clinical CR was 95.7%. In patients with successful lymphatic mapping, 70.7% of patients had residual axillary metastases. The overall accuracy and false-negative rate were 87.9% and 17.1% in all patients: 95.5% and 10.0% in patients with clinical CR of ALN, and 83.3% and 19.4% in patients with residual axillary disease after PST. Conclusion Our findings suggest that SLNB may be feasible in patients with initial documented ALN metastasis who have clinical CR for metastatic ALN after PST. Further investigation in a prospective setting should be performed to confirm our results.
THE INTER‐RELATIONSHIP OF THYROID HORMONES, VITAMIN A AND THEIR BINDING PROTEINS FOLLOWING ACUTE STRESS

The effects of surgical stress on the metabolism of the retinol‐binding‐protein‐thyroxine‐binding‐prealbumin complex were investigated. The immediate post‐surgical period was characterized by a rapid decline in the serum concentration of retinol, retinol binding protein and triiodothyronine and an increase in the 24 h urinary excretion of retinol, retinol‐binding‐protein and thyroxine. Similar, but less pronounced, changes were seen in other subjects suffering acute myocardial infarction but were not observed in normal healthy euthyroid males or in pre‐operative euthyroid patients. The preparation of specific anti‐retinol binding protein anti‐serum and the use of this in ‘monorocket’ immunoelectrophoresis are also described.
Fully Automated Driving

Objective: An experiment was performed in a driving simulator to investigate the impacts of practice, trust, and interaction on manual control recovery (MCR) when employing fully automated driving (FAD). Background: To increase the use of partially or highly automated driving efficiency and to improve safety, some studies have addressed trust in driving automation and training, but few studies have focused on FAD. FAD is an autonomous system that has full control of a vehicle without any need for intervention by the driver. Method: A total of 69 drivers with a valid license practiced with FAD. They were distributed evenly across two conditions: simple practice and elaborate practice. Results: When examining emergency MCR, a correlation was found between trust and reaction time in the simple practice group (i.e., higher trust meant a longer reaction time), but not in the elaborate practice group. This result indicated that to mitigate the negative impact of overtrust on reaction time, more appropriate practice may be needed. Conclusions: Drivers should be trained in how the automated device works so as to improve MCR performance in case of an emergency. Application: The practice format used in this study could be used for the first interaction with an FAD car when acquiring such a vehicle.
The effectiveness of transforaminal epidural steroid injections on radicular pain, functionality, psychological status and sleep quality in patients with lumbar disc herniation.

BACKGROUND The significance of fluoroscopy-guided transforaminal epidural steroid injections (TFESI) in the treatment of lumbar disc herniation (LDH) is well known. The aim of our study is to investigate the effectiveness of TFESI on radicular pain, functionality, psychological status, and sleep quality in patients with LDH. METHODS Seventy-five LDH patients (36 males, 39 females) were enrolled in the study. All patients received a fluoroscopically guided TFESI (betamethasone 40 mg, lidocaine 2%). Also all patients were evaluated according to (with the visual analogue scale) radicular pain, Oswestry disability index (ODI), hospital axiety and depression scale, and Pittsburgh sleep quality index (PSQI) at baseline, at two weeks, and 12 months post injections. RESULTS Mean age was 46.4 ± 12.5. When compared to baseline measurements there were significant improvements in radicular pain, ODI, modified schober, Laseque angle, finger to floor distance, depressive symptoms and PSQI scores at two weeks and 12 months after injection. Improvement of at least 50% in radicular pain relief, ODI score and sleep quality index was detected at two weeks 83%, 71%, 69% respectively. This rate showed regression at 12 months of 73%, 65% and 62% respectively. Duration of symptoms was significantly negatively correlated with changes in scores of radicular pain, ODI, depressive symptoms, and PSQI. There were no significant correlations with symptom duration and anxious symptoms. CONCLUSION Fluoroscopy guided TFESI had positive effects on radicular pain, functionality, depressive symptoms and sleep quality in management of LDH.
Counselors' Reports of Performance: Facilitative and Debilitative Cognitions in the Job Interview.

Thirty vocational counselors participated in a job interview thought-listing procedure. Potentially facilitative and debilitative cognitions relating to the job interview were grouped and analyzed in terms of their frequency of occurrence and their impact. The results show that the interviewee's cognitions relate to social evaluation and the skilled performance of interview tasks.
SYMPOSIUM REPORT: MAIN PAPER Sustaining Rural Landscapes: the role of integrated tourism

The aim of a European Union-funded research project entitled ‘Supporting and Promoting Integrated Tourism in Europe’s Lagging Rural Regions’ (SPRITE) is to analyse and develop the potential for better-integrated tourism in the rural landscapes of Europe. Integrated tourism can be defined as that which is explicitly linked to the localities in which it takes place and, in practical terms, has clear connections with local resources, activities, products, production and service industries, and a participatory local community. Enhancing the sustainable economic potential of rural landscapes requires partnerships among rural people and the sustainable yet productive use of rural resources. A ‘culture economy’ approach to integrated tourism is proposed, which emphasizes the importance of local identity, the strategic commodification of resources and of place, and the importance of extra-local forces in enabling local activities. It is suggested that this approach may represent a shift beyond more traditional approaches to rural development.
Embedded autopilot for accurate waypoint navigation and trajectory tracking: Application to miniature rotorcraft UAVs

In this paper, we describe a miniature flight platform weighing less than 700 grams and capable of waypoint navigation, trajectory tracking, precise hovering and automatic takeoff and landing. In an effort to make advanced autonomous behaviors available to mini and micro rotorcraft, a lightweight/portable and inexpensive Guidance, Navigation, and Control system (GN&C) was developed. To compensate for the weaknesses of the low-cost equipment, we put our efforts in obtaining a reliable model-based nonlinear controller. The GN&sC system was implemented on a small four rotor helicopter which has undergone an extensive program of flight tests, resulting in various flight behaviors under autonomous control from takeoff to landing. Flight test results that demonstrate the operation of the GN&C algorithms on a real MAV are presented.
Using Verged Cameras in Visual NavigationClaus

The eld of computer vision has for many years addressed the use of visual information for robot navigation and tracking. However, only a few examples of systems running in industrial environments have been demonstrated to work. This paper concerns construction of the control of a robot arm in a well deened automatic laboratory, where the robot is to move samples from one machine to the other using visual information from two verged video cameras. We derive two methods to eliminate some of the errors that typically occurs when using vision in robot navigation. The errors arise in the calibration and segmentation procedures. The rst type of error is compensated by the building an a priori map of the errors, and then using the map to compensate for the calibration errors in the following measurements. The segmentation errors are eliminated by use of temporal context, ie. an improvement over time is performed by integrating information from multiple images. Some initial experiments of the error compensation is presented, as well as the overall system control.
Human Coronavirus 229E Binds to CD13 in Rafts and Enters the Cell through Caveolae

ABSTRACT CD13, a receptor for human coronavirus 229E (HCoV-229E), was identified as a major component of the Triton X-100-resistant membrane microdomain in human fibroblasts. The incubation of living fibroblasts with an anti-CD13 antibody on ice gave punctate labeling that was evenly distributed on the cell surface, but raising the temperature to 37°C before fixation caused aggregation of the labeling. The aggregated labeling of CD13 colocalized with caveolin-1 in most cells. The HCoV-229E virus particle showed a binding and redistribution pattern that was similar to that caused by the anti-CD13 antibody: the virus bound to the cell evenly when incubated on ice but became colocalized with caveolin-1 at 37°C; importantly, the virus also caused sequestration of CD13 to the caveolin-1-positive area. Electron microscopy confirmed that HCoV-229E was localized near or at the orifice of caveolae after incubation at 37°C. The depletion of plasmalemmal cholesterol with methyl β-cyclodextrin significantly reduced the HCoV-229E redistribution and subsequent infection. A caveolin-1 knockdown by RNA interference also reduced the HCoV-229E infection considerably. The results indicate that HCoV-229E first binds to CD13 in the Triton X-100-resistant microdomain, then clusters CD13 by cross-linking, and thereby reaches the caveolar region before entering cells.
The Path to Graduation: Factors Predicting On-Time Graduation Rates

This study uses an integrative persistence model to examine college students' expected time-to-degree as a function of sociological and economic factors. The data used in this study are from the 2010 Ohio Student Financial Wellness Survey (SFWS), a web-based survey of undergraduate college students. Of the students surveyed, 25% indicated that they plan to take longer than 4 years to complete their undergraduate degree. Findings from the study indicate college environment and personal financial characteristics are important factors in determining time-to-degree. Students who overspend, have a car loan, credit cards, or high debt, and those who feel stress from their finances are more likely to take longer than 4 years. Students are more likely to finish in 4 years or less if they live or work on campus, have a high GPA, or have met with a financial counselor or advisor. Implications for higher education administrators and parents are discussed.