Miracle-dz/UniFAR-FTUs huggingface dataset:
DEXA-assessed regional body composition changes in young female military soldiers following 12-weeks of periodised training

Dual-energy X-ray absorptiometry (DEXA) was used to assess whole body and regional soft tissue mass, fat mass and lean body mass compositional changes in 68 female recruits (age 20.8 ± 1.14 years; body mass 59.5 ± 8.79 kg; stature 159.57 ± 5.53 cm) pre- and post 12-weeks of military basic training. A decrease in total body fat tissue mass (10.2%) and regional percent fat (10.9%) was measured with an increase in total lean body mass (8.7%). Of interest were the differences in the responses in the tissue composition of the arms (16.2% loss in fat mass with an 11.6% gain in lean mass), trunk (17.0% decrease in fat mass with a 10.4% increase in lean mass) and the legs (10.5% increase in lean mass but no change in fat mass). These findings show the importance of considering regional rather than whole body composition changes when assessing the effects of a training programme. Statement of Relevance: Female soldiers experienced a change in total body fat tissue (−10.2%) and lean body mass (+8.7%) after basic training; however, no significant fat mass decrease was evident in the leg region. Regional rather than whole body composition changes need to be considered when assessing the effects of a training programme.
Collapsed houses automatic identification based on texture changes of post-earthquake aerial remote sensing image

Collapsed houses in city are one of the most important destructions after earthquake. The area, amount and rate of collapsed houses are the most essential data sources to decide how to reconstruct in the disaster area after earthquake. It is often difficult to access high-resolution remote sensing satellite images in time only with satellite sensors in the area. For example, after the Wenchuan earthquake on May 12 2008, high-resolution satellite remote sensing images had not been acquired after a few days in which all actions have to be taken for disaster mitigation and relief. With various aviation flight platforms, the aerial remote sensing images are obtained in time at a relatively short period of time with better weather in the earthquake zones. So how to rapidly identify and detect the damage building is the most important problem. In this paper, through the texture changes of aerial remote sensing images, the method of housing collapsed automatically determination is expounded. The approach for detecting the damaged buildings after earthquake is different to visual identification of the post-event aerial images. The approach utilizes the texture difference between the buildings and the collapsed buildings. It is based on an idea that if a building collapsed, it will produce more complex texture. After we calculate the texture complexity parameter, the building may has collapsed if the texture complexity parameter is beyond threshold. After Wenchuan earthquake, the aerial remote sensing images are testified by this way in Beichuan, Wenchuan and Anxian. The rate of houses collapsed and the ratio of the edge of texture are strongly correlated. If the rate is beyond 0.15, the house will collapse over eighty percent, and if the rate is under 0.10, the percentage drops. Therefore, through the ratio of the edge of pixels and the number of regional architecture of the region pixels, to estimate the rate of the houses collapsed is feasible and effective.
DRD2 promoter region variation as a predictor of sustained response to antipsychotic medication in first-episode schizophrenia patients.

OBJECTIVE All antipsychotics act on the dopamine D(2) receptor. The present study extends prior pharmacogenetic investigations of the D(2) receptor gene (DRD2) by examining, in first-episode schizophrenia patients, promoter region variation as a predictor of response time to two first-line atypical antipsychotics. METHOD Patients experiencing their first episode of schizophrenia (N=61) were genotyped for two DRD2 promoter region polymorphisms (A-241G and -141C Ins/Del) and were randomly assigned to receive 16 weeks of treatment with either risperidone or olanzapine. Time until sustained response (two consecutive ratings without significant positive symptoms) for rare allele carriers versus wild types was examined by using Kaplan-Meier curves. RESULTS Relative to wild type homozygotes, G carriers (A-241G) exhibited a significantly faster time until response, whereas -141C Del carriers took a significantly longer time to respond. Diplotype analysis revealed similar results. CONCLUSIONS These findings suggest that variation in the D(2) receptor gene can, in part, explain variation in the timing of clinical response to antipsychotics in patients with first-episode schizophrenia.
Middle School Teachers' Use and Perceptions of Digital Game-Based Learning

Middle School Teachers’ Use and Perceptions of Digital Game-Based Learning by Spencer Vogt MS, University of Nebraska, Kearney, 2011 BA, York College, 2005 Dissertation Submitted in Partial Fulfillment of the Requirements for the Degree of Doctor of Philosophy Educational Technology Walden University November 2018
MR Imaging–Based Correction for Partial Volume Effect Improves Detectability of Intractable Epileptogenic Foci on Iodine 123 Iomazenil Brain SPECT Images: An Extended Study with a Larger Sample Size

BACKGROUND AND PURPOSE: It has been suggested, on the basis of a previous pilot study conducted in a small number of patients, that MR imaging–based PVE correction in I-123 iomazenil brain SPECT improves the detectability of cortical epileptogenic foci. In the present study, we performed an investigation by using a larger sample size to establish the effectiveness of the PVE correction and to conduct a detailed evaluation based on the histologic classification of lesions. MATERIALS AND METHODS: Seventy-five patients (male/female, 37/38; age, 28 ± 12 years) with intractable epilepsy who had undergone surgical treatment were enrolled in this study. I-123 iomazenil SPECT and MR imaging examinations were performed before the operation in all patients. I-123 iomazenil SPECT images with and without MR imaging–based PVE correction were assessed visually and by semiquantitative analysis based on the AI(%) of the SPECT count in the resected lesions. RESULTS: The sensitivity, specificity, and accuracy of foci detection by visual assessment were significantly higher after PVE correction compared with the values obtained before the correction. The results of the semiquantitative analysis revealed that the asymmetry of the SPECT counts was significantly increased after the PVE correction in the surgically resected lesions in cases of mesial temporal sclerosis, tumor, and malformations of cortical development. CONCLUSIONS: The effectiveness of MR imaging–based PVE correction in I-123 iomazenil brain SPECT in improving the detection of cortical epileptogenic foci with abnormal histologic findings was established by our investigation conducted on a large sample size.
A Design Method of Saturation Test Image Based on CIEDE2000

In order to generate color test image consistent with human perception in aspect of saturation, lightness, and hue of image, we propose a saturation test image design method based on CIEDE2000 color difference formula. This method exploits the subjective saturation parameter C′ of CIEDE2000 to get a series of test images with different saturation but same lightness and hue. It is found experimentally that the vision perception has linear relationship with the saturation parameter C′. This kind of saturation test image has various applications, such as in the checking of color masking effect in visual experiments and the testing of the visual effects of image similarity component.
Intraoperative use of a chest physiotherapy system during whole lung lavage for pulmonary alveolar proteinosis

Pulmonary alveolar proteinosis (PAP) is a rare condition caused by the excessive alveolar accumulation of surfactant proteins. The current standard of care for removing these secretions is through therapeutic whole lung lavage (WLL). We describe two successful cases of bilateral WLL involving the novel use of the Vest™ chest physiotherapy system thereby avoiding the need for extensive changes in patient position in the intraoperative period. In brief, it involves the induction of general anesthesia followed by single-lung ventilation while simultaneously performing large volume lavages on the nonventilated lung. The washout was enhanced using the Vest™ system.
The Statistical Measurement of the Elasticity of Demand for Beef

Both in technical discussions of value and in the practical workings of our price-making system, one factor which constantly and significantly presents itself concerns the character of the demand schedule or so-called "elasticity of demand. " There is hardly a text-book on economics in existence which does not devote a good deal of space to the exposition of the part played by this factor in price determination under both free competition and monopoly conditions. Such discussions, however, are merely qualitative in character. In so far as actual illustrations are introduced in the exposition they are merely for illustrative purposes, and are simply hypothetical figures chosen arbitrarily by the given writer. Excellent as this may be, it is not enough. In a great variety of the situations which develop in the actual working of our price-organized society it becomes necessary or at least highly desirable that the business man, the official executive, or the legislator should be able to arrive at some quantitative measure of the elasticity of demand. Intelligent action or a correct appraisal of the probable effect of a given course can be arrived at only by knowing the intensity of effective demand which the consuming public exerts at varying levels of price. Two illustrations will suffice. The trader who buys cotton or other staple commodities for resale in a future market must have the safety of any given course determined by a shrewd knowledge of the tenacity with which the public follow a rising market, or the extent of downward revision in the price basis which will be necessary in view of increased abundance of a given product. One of the most striking cases of this sort comes to mind in connection with co-operative
The Impact of Cognitive and Psychiatric Impairment of Psychotic Disorders on the Test of Memory Malingering (TOMM)

The author analyzes the scores of inpatient psychiatric patients with varying degrees of cognitive impairment who met criteria for a psychotic disorder on the following tests: the Test of Memory Malingering (TOMM), the California Verbal Learning Test-Second Edition, Conner’s Continuous Performance Test-Second Edition, and the Brief Psychiatric Rating Scale-Expanded Version. Group 1 consisted of psychotic-disordered patients with significant concentration problems (concentration impersistence = 29). Group 2 consisted of psychotic disordered patients without significant concentration problems (no concentration impairment = 21). Although psychotic patients with concentration problems showed greater variability across TOMM trials, both groups obtained mean scores above 45 on Trial 2 and the retention trial on the TOMM. These findings indicate that cognitive impairment associated with psychosis generally does not negatively impair TOMM performance to such a level that would produce a false positive on the TOMM. Implications for forensic assessment, study limitations, and future directions are discussed.
Weaknesses of a dynamic identity based authentication protocol for multi-server architecture

Recently, Li et al. proposed a dynamic identity based authentication protocol for multi-server architecture. They claimed their protocol is secure and can withstand various attacks. But we found some security loopholes in the protocol. Accordingly, the current paper demonstrates that Li et al.'s protocol is vulnerable to the replay attack, the password guessing attack and the masquerade attack.
Mechanism of cardiotoxicity induced by a marine toxin isolated from Ptychodiscus brevis.

An organophosphate toxin of marine origin isolated from red tide dinoflagellate P. brevis produced a dose-dependent dual effect on rat atria, i.e. positive inotropic effect at low concentrations (2.8 x 10(-8) to 8.4 x 10(-7) M) and negative inotropic and chronotropic responses at an elevated dose (4.8 x 10(-6) to 7.2 x 10(-4) M). The negative chronotropic and inotropic responses of the toxin were potentiated with physostigmine and ouabain whereas antagonized by atropine and hemicholinium-3 pretreatments and those effects remained unaltered by isoproterenol, phenylephrine and ouabain pretreatments. The results indicate that the toxin induced negative inotropic and chronotropic effects are mediated through release of acetylcholine from the nerve endings and consequent activation of muscarinic receptor. In atria exposed to guanethidine, bretylium, propranolol and tyramine tachyphylaxis, the positive inotropic response of the toxin was not modified. However, the response was antagonized by EGTA, nifedipine, ryanodine, calcium-free ringer and potentiated with caffeine and amiloride pretreatments. The results suggest that the positive inotropic effect of the toxin is mediated through Ca2+ influx and impairment of Na+/Ca2+ exchange process.
THE REFLECTION COMPONENT FROM CYGNUS X-1 IN THE SOFT STATE MEASURED BY NuSTAR AND SUZAKU

The black hole binary Cygnus X-1 was observed in late 2012 with the Nuclear Spectroscopic Telescope Array (NuSTAR) and Suzaku, providing spectral coverage over the ∼1–300 keV range. The source was in the soft state with a multi-temperature blackbody, power law, and reflection components along with absorption from highly ionized material in the system. The high throughput of NuSTAR allows for a very high quality measurement of the complex iron line region as well as the rest of the reflection component. The iron line is clearly broadened and is well described by a relativistic blurring model, providing an opportunity to constrain the black hole spin. Although the spin constraint depends somewhat on which continuum model is used, we obtain a* > 0.83 for all models that provide a good description of the spectrum. However, none of our spectral fits give a disk inclination that is consistent with the most recently reported binary values for Cyg X-1. This may indicate that there is a >13° misalignment between the orbital plane and the inner accretion disk (i.e., a warped accretion disk) or that there is missing physics in the spectral models.
Rho-kinase activation in patients with pulmonary arterial hypertension.

ulmonary arterial hypertension (PAH) is a life-threatening syndrome resulting from restricted pulmonary arterial circulation, which leads to a pathological increase in pulmonary vascular resistance (PVR) and ultimately to right heart failure.1,2 Multiple pathogenic factors causing the imbalance in homeostasis between vasoconstriction and vasodilatation, and the imbalance of cell proliferation and apoptosis, have been implicated in the development of PAH.1,2 Although progression of the disease is still inevitable, there has been advances in basic and clinical research throughout the past decade. With increasing insight into the pathology of PAH, the disease has also attracted considerable interest in drug development in recent years. Based on the evidence from prospective randomized clinical trials, 3 main strategies (administration of prostacyclin, antagonism of endothelin receptors, and inhibition of phosphodiesterase-type 5 (PDE5)) represent the current first-line treatments.3,4 Compared with the conventional therapeutic management of PAH, these agents have a positive effect on the course of the disease and improve patient outcomes. Furthermore, basic studies have identified several future therapeutic targets, such as tyrosine kinase, soluble guanylate cyclase, vasoactive intestinal peptide and 5-HT transporter (5-HTT). Added to these, Rho-kinase has become an important target for the treatment of PAH.2,5
[Influence of bronchoscopy on nitric oxide in exhaled air].

UNLABELLED Nitric oxide has been extensively studied as a noninvasive marker of airway inflammation, especially in asthma. Assuming, bronchoscopy can produced not only systemic but also local inflammatory response we hypothesized that bronchofiberoscopy can be responsible for an increase in nitric oxide synthesis with resulting increase in fractional concentration of exhaled nitric oxide (FE(NO)). Seventeen subjects (10 M, 7 F), at mean age of 53.8+/-14.1 yrs undergoing diagnostic bronchoscopy participated in the study. The indications for bronchoscopy were as follows: lung cancer (n=5; 29%), interstitial lung diseases (n=3; 18%), slowly resolving pneumonia (n=3; 18%), hemoptysis (n=3; 18%), differential diagnosis of asthma/ dyspnea (n=3; 18%). During bronchoscopy bronchial washing (n=7) and bronchoalveolar lavage (BAL) (n=10) has been performed. FE(NO) has been analyzed on-line with chemiluminescence analyzer (NIOX, Aerocrine, Sweden) according to American Thoracic Society guidelines, before and at 1, 2, 3 and 24 hours after bronchoscopy. Mean FE(NO) before bronchoscopy was 19.7+/-4.5 ppb (mean +/- SEM), post - bronchoscopy a decrease with a nadir at second hour (12.1+/-1.5 ppb, p<0.05) was observed, FE(NO) 24 hours after bronchoscopy was not different than baseline (18.4+/-2.5 ppb). There were no differences in the FE(NO) profile in BAL patients when compared to those in whom only the bronchial washing has been performed. CONCLUSIONS Bronchoscopy leads to a significant decrease in exhaled nitric oxide. The underlying mechanisms are unclear. Future studies including analysis of other inflammatory markers are needed to explain these changes.
Reconfiguration of Carrier-Based Modulation Strategy for Fault Tolerant Multilevel Inverters

This paper focuses on the fault-tolerance potential of multilevel inverters with redundant switching states such as the cascaded multilevel inverters and capacitor self-voltage balancing inverters. The failure situations of the multilevel inverters are classified into two types according to the relationship between output voltage levels and switching states. The gate signals can be reconfigured according to the failure modes when some of the power devices fail. The reconfiguration method is discussed for phase disposition PWM strategy (PDPWM) and phase shifted PWM strategy (PSPWM) in the paper and it can be extended for other carrier-based PWM strategies easily. Balanced line-to-line voltage will be achieved with the proposed method when device failure occurs. Furthermore, the circuit structures can be the same as the general ones and the voltage stress of the devices does not increase. Simulation and experimental results are included in the paper to verify the proposed method.
Building Ambidexterity Into an Organization

For a firm to succeed over the long term it needs to master both adaptability and alignment ? an attribute sometimes referred to as ambidexterity. The concept is alluring, but the evidence suggests that most companies have struggled to apply it. The standard approach has been to create separate structures for different types of activities. But separation can also lead to isolation, and many R&D and business development groups have failed because of their lack of linkages to the core businesses. In an attempt to shed new light on the discussion, the authors develop and explore their concept of contextual ambidexterity, which calls for individual employees to make choices between alignment-oriented and adaptation-oriented activities in the context of their day-to-day work. The authors introduce this as a complementary concept to traditional structural ambidexterity. By means of their survey- and interview-based research ? which took place over a three-year period and involved 4,195 respondents across 41 business units in 10 multinational firms ? the authors identify the four behaviors displayed by ambidextrous individuals, each of which involves taking independent, adaptive action in the service of overall company goals. They then present a framework for describing and analyzing which organizational contexts encourage or discourage such behaviors. They link organizational context to ambidexterity and, in turn, ambidexterity to high performance. Finally, the authors describe how companies such as Nokia, Ericsson, Oracle and Renault have been able to create such high performance contexts, and they offer managers guidance on how to create them in their own companies.
Theory and Design of a Quadrature Analog-to-Information Converter for Energy-Efficient Wideband Spectrum Sensing

A flexible bandwidth, blind sub-Nyquist sampling approach referred to as the quadrature analog-to-information converter (QAIC) is proposed. The QAIC relaxes the analog front-end bandwidth requirements at the cost of some added complexity compared to the modulated wideband converter (MWC) for an overall improvement in sensitivity and energy consumption. An approach for detailed frequency domain analysis of the proposed system with linear impairments is developed. A process for selecting QAIC parameter values is illustrated through examples. The benefits of the QAIC are highlighted with cognitive radio use cases where a wide range of spectrum is observed at various resolution bandwidth settings. We demonstrate that the energy consumption of the QAIC is potentially two orders of magnitude lower than the swept-tuned spectrum analyzer (STSA) and an order of magnitude lower than the MWC. We also demonstrate that the QAIC significantly improves upon the sensitivity performance delivered by the MWC.
Early treatment of ruptured aneurysms with Guglielmi detachable coils: effect on subsequent bleeding.

The major causes of mortality and morbidity in patients surviving the rupture of a saccular aneurysm are subsequent bleeding and vasospasm. The purpose of this study was to evaluate the influence of early treatment of ruptured aneurysms with Guglielmi detachable coils on the incidence of subsequent bleeding. Thirteen patients were treated within 72 hours of initial aneurysm rupture with Guglielmi detachable coils. Excluding three patients who died 2, 4, and 12 weeks after initial hemorrhage, all others have been followed up for intervals between 6 and 36 months (mean, 16 mo). None of these have had either clinical or radiographic evidence of subsequent bleeding. Assuming that there is a 30% incidence of subsequent bleeding in conservatively (nonsurgically) treated patients, the 0% subsequent bleed rate observed in this subgroup was significant at a P value of 0.01. Only one procedure-related complication occurred in this series, and 9 of 13 (69%) aneurysms were 100% occluded at the time of initial treatment. All aneurysms were at least 90% occluded at the end of initial treatment. In addition to reducing the risk of subsequent bleeding, early treatment facilitated the institution of an aggressive approach for management of both vasospasm and increased intracranial pressure. Patient outcome, as measured by the Glasgow Outcome Scale, was good in 9 of 13 (69%), poor in 1 of 13 (8%), and death in 3 of 13 (23%) patients. The results of this study suggest that early Guglielmi detachable coil treatment of ruptured aneurysms may be effective in reducing the incidence of subsequent bleeding and can be performed with a low incidence of complications. (ABSTRACT TRUNCATED AT 250 WORDS)
ECG Denoising Using Parameters of ECG Dynamical Model as the States of an Extended Kalman Filter

In this paper an efficient filtering procedure based on the extended Kalman filter (EKF) has been proposed. The method is based on a modified nonlinear dynamic model, previously introduced for the generation of synthetic ECG signals. We have suggested simple dynamics as the governing equations for the model parameters. Since we have not any observation for these new state variables, they are considered as hidden states. Quantitative evaluation of the proposed algorithm on the MIT-BIH signals shows that an average SNR improvement of 12 dB is achieved for a signal of -5 dB. The results show improved output SNRs compared to the EKF outputs in the absence of these new dynamics.