Miracle-dz/UniFAR-FTUs huggingface dataset:
Un esprit sain dans un corps sain : promouvoir le sport au travail

Comment le sport propose a des employes peut-il pallier les problemes croissants de sante mentale au travail? Cet article vise a repondre a cette question en resumant les nombreux bienfaits de la pratique sportive pour les employes et les employeurs. Ensuite, nous presentons la panoplie des outils et des approches que les employeurs peuvent adopter pour promouvoir la pratique sportive selon deux continuums : un continuum allant des pratiques dans le milieu de travail a celles executees a l’exterieur du milieu de travail, et un autre continuum allant des pratiques de gestion communiquant ou symbolisant l’attrait de la pratique sportive a l’exercice d’activites sportives individuelles ou collectives. S’appuyant sur des exemples tires de trois grandes entreprises, l’article traite aussi des conditions de succes a respecter et des defis a relever dans l’elaboration et la gestion de programmes destines a promouvoir le sport au sein des organisations.Fonction : GRH, management, autres
Extensibility of the human pulmonary trunk.

The mechanical properties of the walls of blood vessels have an important influence on the flow of blood and passage of pulse waves along them. Though a certain amount of information is available concerning the mechanical properties of the aorta and its main branches (Burton, 1954), we have been unable to find any observations on the pulmonary circulation. Hence, in view of the increasing interest in human pulmonary hmmodynamics, it seemed worth while to investigate the physical characteristics of the wall of the pulmonary trunk in man.
Down-regulation of Notch signaling during corneal epithelial proliferation

Purpose We evaluated the expression and activation of Notch pathway genes in the adult human and murine corneal epithelium during proliferation. Methods The expression of Notch pathway genes in the limbal and central human corneal epithelium was compared by reverse transcription polymerase chain reaction (RT–PCR). Their expression pattern was examined by immunofluorescence and in situ hybridization. The temporal expression of Notch1 during murine wound healing was assessed by RT–PCR. Notch activity was determined using western blot for the Notch intracellular domain (NotchIC). The expression of Hes1 was evaluated in cell culture. Results The expression of Notch1 and Jagged1 was higher in the human limbal epithelium while the expression of Hes1 and Hes5 was higher in the central cornea. Expression of Notch1, Jagged1, and Hes1 was found predominantly in the basal and immediate suprabasal cells. During neonatal corneal development, NotchIC was detected in occasional cells at P10 while at P15 and P90, it was found in the basal and early suprabasal layers. NotchIC was found to be lower in the limbal compared to central corneal epithelium. The expression of Notch1 was lower at 24 h post-wounding but was completely restored in six days. The levels of NotchIC were decreased at 24 h post-wounding and after application of topical phorbol myristate. In vitro, the expression of Hes1 was higher in confluent cells maintained under high calcium conditions. Conclusions The inverse correlation between Notch signaling and the proliferative status of the corneal epithelium is consistent with the idea that Notch plays a role in corneal epithelial differentiation.
Rediscovering Spatial Inequality in Europe: Building Blocks for an Appropriate ‘Regulationist’ Analytical Framework

Regulation theory is of Marxian inspiration, has been strongly influenced by historical analysis and institutionalism, and can be applied to the study of accumulation in and regulation of societies in all eras, of capitalism. But these features of the theory have not prevented many geographers from applying it primarily to the study of the transition from Fordism to post-Fordism. Moreover, many of them have narrowed the research agenda even more by focusing on the feasibility of fashionable but economistic ‘flex spec prof high-tech’ production models for the development strategies of privileged areas. Research efforts have drifted away from the study of ‘undefended cities and regions’. This evolution is, I believe, all the more deplorable given the creation of the Single European Market, with its permissive social charter and the spatially biased reorganization of the structural funds of the Commission of the European Communities. In this paper a methodological viewpoint is defended which contends that progress in the social sciences can be accomplished only through the confrontation of experience and action-orientated research needs with existing theoretical frameworks capable of leading the research in the right direction. Then, an examination is made of the research needs of agents (policymakers, planners, academics, and so on) involved in action which is orientated towards achieving greater intraspatial and interspatial equality in Europe. The extent to which regulation theory is capable of guiding such research, given the ideological influences as well as theoretical refinements it has undergone, is discussed, and it is concluded that further improvements to regulation theory could make it more appropriate for action-orientated research in socioeconomic geography. This conclusion is illustrated for the application of the analysis of socioeconomic development in depressed areas.
Innovation Policies From the European Union: Methods for Classification

This study focuses on taxonomic and typological methods of innovation policies in the European institutional context. Although many types of policies affect innovation, no universally accepted criteria exist to classify them. As innovation policy in a myriad of thematic areas—systemic model—has become pluralized, this article offers a method for classification. Such policies are grouped and categorized according to biological and neofunctional approaches.
Task 3a: Team YORKU

We used learning-to-rank methods for training ranking model. Due to the limited number of training queries, we split them and conducted 5-fold cross validation. We set the proportion of training and testing as 4 : 6. For the features used in learning the model, a total of 231 features that are from multiple information retrieval models with different parameter settings were adopted. For the baseline run, we used Random Forest method to train the models with 5-fold cross validation. Only the binary relevance information were taken into account while training the model. Five trained models from 5-fold cross validation were used on the testing data to predict scores, and then we used equal weights to linearly combine the results given by different models. For run #5, we used 8 learning to rank methods to train models separately and linearly combine them together, and the binary relevance judgment was used as well. For run #6 and #7, graded relevance were taken into consideration. The difference between run 6# and #7 is that for run #6, multiple learning-to-rank methods were used while for run #7, only Random Forest method was used. The best result of the four runs is achieved by run #5, which used multiple models combination based on binary relevance judgment.
The accuracy of sound duration representation in the human brain determines the accuracy of behavioural perception

In recent years, the links between neural activity and perception have been an area of interest in cognitive neuroscience. Combined psychophysiological and psychophysical experiments provide a new powerful tool for establishing the relationship between neural activity and perceptual performance. In animals, intracellular recordings combined with psychophysical detection indices have revealed that a particular neuron or set of neurons can play a critical role in the generation of a perceptual event, showing detection functions (referred to as neurometric functions) which are remarkably similar to psychophysical detection functions, or psychometric functions ( Parker & Newsome, (1998) Annu. Rev. Neurosci. , 21, 227–277). As noninvasive techniques for recording neural activity are now available, studies combining neuroelectric and psychophysical measures in humans are sparse. In the present study, the accuracy of the human brain in detecting differences in sound duration and the subject's ability to perceive the same differences were tested by means of mismatch negativity (MMN) and the distance between the distributions of false alarms and hits (sensitivity index d′), respectively. It was found that the accuracy of the human auditory system to represent sound duration information is related to the duration context in which the sounds are heard, and that these contextual representations determine the accuracy of perception at the behavioural level.
Contested Ground: The Basis of Teacher Leadership in Two Restructuring High Schools

In an analysis of evolving teacher leadership in 2 restructuring high schools, the image of "contested ground" illuminates the ways in which traditions of subject specialism shape assumptions about the exercise of leadership among secondary teachers. The analysis is prefaced by a brief account of the legacy of subject specialism and the pervasive but variable precedent of the department head. Case study data permit comparisons of traditional department head roles with "restructured" leadership roles that span subject boundaries. Subject expertise proves a powerful warrant for teacher leadership and a basis for professional community even in the context of interdisciplinary structures. Claims to subject expertise also supply a resource on which secondary teachers rely in mediating institutional and collective controls on their teaching. The study challenges simplistic stereotypes of the "subject-centered" high school teacher but also demonstrates the power that subject affiliation retains as high schools restructure.
Parecoxib, valdecoxib, and cardiovascular risk.

Selective inhibitors of cyclooxygenase (COX)-21 depress prostacyclin (PGI2) but not COX-1–derived thromboxane A2. The effects of thromboxane A2 would be exaggerated during treatment with COX-2 inhibitors, potentially predisposing patients to heart attack and stroke.2 A randomized controlled trial in patients undergoing coronary artery bypass graft (CABG) surgery and receiving either placebo or 40 mg parecoxib (Dynastat; Pfizer), the intravenously administered prodrug of valdecoxib (Bextra; Pfizer), followed by oral valdecoxib 40 mg BID for 14 days, revealed a cluster of cardiovascular events.3 In a second study, one group received parecoxib/valdecoxib, another …
Mutant LRP6 Impairs Endothelial Cell Functions Associated with Familial Normolipidemic Coronary Artery Disease

Mutations in the genes low-density lipoprotein (LDL) receptor-related protein-6 (LRP6) and myocyte enhancer factor 2A (MEF2A) were reported in families with coronary artery disease (CAD). We intend to determine the mutational spectrum of these genes among hyperlipidemic and normolipidemic CAD families. Forty probands with early-onset CAD were recruited from 19 hyperlipidemic and 21 normolipidemic Chinese families. We sequenced all exons and intron-exon boundaries of LRP6 and MEF2A, and found a novel heterozygous variant in LRP6 from a proband with normolipidemic CAD. This variant led to a substitution of histidine to tyrosine (Y418H) in an evolutionarily conserved domain YWTD in exon 6 and was not found in 1025 unrelated healthy individuals. Co-segregated with CAD in the affected family, LRP6Y418H significantly debilitated the Wnt3a-associated signaling pathway, suppressed endothelial cell proliferation and migration, and decreased anti-apoptotic ability. However, it exhibited no influences on low-density lipoprotein cholesterol uptake. Thus, mutation Y418H in LRP6 likely contributes to normolipidemic familial CAD via impairing endothelial cell functions and weakening the Wnt3a signaling pathway.
When Corporate Social Responsibility (CSR) Increases Performance: Exploring the Role of Intrinsic and Extrinsic CSR Attribution

This study investigates whether employees attribute different motives to their organization’s corporate social responsibility (CSR) efforts and if these motives influence employee performance. Specifically, we investigate whether employees could distinguish between intrinsic and extrinsic CSR motives by surveying 229 employee– supervisor dyads from various industries (companies that have reputable CSR programs in Portugal), and the impact of these perceptions on in-role and extra-role performance of subordinates. We found that employee task performance increases when employees attribute both intrinsic and extrinsic motives for CSR. Moreover, when employees perceive that their organization invests in a CSR practice that is both intrinsic and extrinsic, they also tend to exert extra effort in their work. Theoretical and practical implications are also discussed alongside future research directions.
Distinct Cellular Basis for Early Cardiac Arrhythmias, the Cardinal Manifestation of Arrhythmogenic Cardiomyopathy, and the Skin Phenotype of Cardiocutaneous Syndromes

Rationale: Arrhythmogenic cardiomyopathy is caused primarily by mutations in genes encoding desmosome proteins. Ventricular arrhythmias are the cardinal and typically early manifestations, whereas myocardial fibroadiposis is the pathological hallmark. Homozygous DSP (desmoplakin) and JUP (junction protein plakoglobin) mutations are responsible for a subset of patients with arrhythmogenic cardiomyopathy who exhibit cardiac arrhythmias and dysfunction, palmoplanter keratosis, and hair abnormalities (cardiocutaneous syndromes). Objective: To determine phenotypic consequences of deletion of Dsp in a subset of cells common to the heart and skin. Methods and Results: Expression of CSPG4 (chondroitin sulfate proteoglycan 4) was detected in epidermal keratinocytes and the cardiac conduction system. CSPG4pos cells constituted ≈5.6±3.3% of the nonmyocyte cells in the mouse heart. Inducible postnatal deletion of Dsp under the transcriptional control of the Cspg4 locus led to ventricular arrhythmias, atrial fibrillation, atrioventricular conduction defects, and death by 4 months of age. Cardiac arrhythmias occurred early and in the absence of cardiac dysfunction and excess cardiac fibroadipocytes, as in human arrhythmogenic cardiomyopathy. The mice exhibited palmoplantar keratosis and progressive alopecia, leading to alopecia totalis, associated with accelerated proliferation and impaired terminal differentiation of keratinocytes. The phenotype is similar to human cardiocutaneous syndromes caused by homozygous mutations in DSP. Conclusions: Deletion of Dsp under the transcriptional regulation of the CSPG4 locus led to lethal cardiac arrhythmias in the absence of cardiac dysfunction or fibroadiposis, palmoplantar keratosis, and alopecia, resembling the human cardiocutaneous syndromes. The findings offer a cellular basis for early cardiac arrhythmias in patients with arrhythmogenic cardiomyopathy and cardiocutaneous syndromes.
Dynamic bandwidth and wavelength allocation with coexistence of transmission technologies in TWDM PONs

In a Passive Optical Network (PON), the possibility of smooth upgrading the network infrastructure is an important requirement for network providers as it allows to minimize initial investments for networks deployment. During the upgrade process, it is expected a coexistence of new and old end-users, i.e., Optical Network Units (ONU), with diverse transceiver technologies. Our work focuses on the scenario where the network is upgraded from a TDM PON to a hybrid WDM/TDM PON (both short-reach and long-reach), and where the transceivers used in the old TDM PON can coexist with the new transceivers adopted in the hybrid WDM/TDM PON. In this work, we propose new Dynamic Bandwidth and Wavelength Allocation (DBWA) algorithms that solve the problem of managing the traffic originated by end-user transceivers with different characteristics. Specifically, in this paper we focus on the case of transceivers characterized by different tuning time. To investigate the importance of a DBWA which can specifically manage the traffic originated by transceivers with different tuning time, we also compare them to DBWAs which are not aware that different transmission technologies with different requirements coexist in the network. Finally, we test these DBWAs in different network scenarios (e.g., short-reach (PON) and long-reach (LR-PON) scenarios), and discuss what are the network parameters that mostly affect the algorithms performance.
A new curvelet transform based method for extraction of red lesions in digital color retinal images

Red lesions in the form of Microaneurysms (MAs) and Hemorrhages (HMs) are among the first explicit signs of diabetic retinopathy (DR). Hence robust detection of these lesions is an important diagnostic task in computer assistance systems. In this paper we present a new curvelet based algorithm to separate these red lesions from the rest of the color retinal image. In order to prevent fovea to be considered as red lesion, we introduce a new illumination equalization algorithm and apply that to green plane of retinal image. In the next stage, we apply digital curvelet transform (DCUT) to produced enhanced image and modify curvelet coefficients in order to lead red objects to zero. Then we separate these lesions as candidate region by applying an appropriate threshold. Finally, the total structure of blood vessel is extracted employing a curvelet-based technique and the false positives (FPs) are eliminated by subtracting the vessel structure from the candidate images. Experiments on 89 retinal images of diabetic patients indicate that we are able to achieve 94% sensitivity and 87% specificity in detection of red lesion.
E ects of adaptive re nement on the inverse EEG solutionDavid

One of the fundamental problems in electroencephalography can be characterized by an inverse problem. Given a subset of electrostatic potentials measured on the surface of the scalp and the geometry and conductivity properties within the head, calculate the current vectors and potential elds within the cerebrum. Mathematically the generalized EEG problem can be stated as solving Poisson's equation of electrical conduction for the primary current sources. The resulting problem is mathematically ill-posed i.e., the solution does not depend continuously on the data, such that small errors in the measurement of the voltages on the scalp can yield unbounded errors in the solution, and, for the general treatment of a solution of Poisson's equation, the solution is non-unique. However, if accurate solutions to such problems could be obtained, neurologists would gain non-invasive access to patient-speciic cortical activity. Access to such data would ultimately increase the number of patients who could be eeectively treated for pathological cortical conditions such as temporal lobe epilepsy. In this paper, we present the eeects of spatial adaptive reenement on the inverse EEG problem and show that the use of adaptive methods allow for signiicantly better estimates of electric and potential elds within the brain through an inverse procedure. To test these methods, we have constructed several nite element head models from magnetic resonance images (MRI) of a patient. The nite element meshes ranged in size from 2724 nodes and 12,812 elements to 5224 nodes and 29,135 tetrahedral elements, depending on the level of discretization. We show that an adaptive meshing algorithm minimizes the error in the forward problem due to spatial discretization and thus increases the accuracy of the inverse solution.
Chicon—a Chinese text manipulation language

Text processing is an important computer application. Due to its importance, a number of text manipulation programming languages have been devised (e.g. Icon). These programming languages are very useful for applications such as natural language processing, text analysis, text editing, document formatting, text generation, etc. However, they were mainly designed to handle English texts, and are ineffective for Chinese. This is because English and Chinese texts are represented very differently in a computer. An English character is mainly represented in 7‐bit ASCII, and its Chinese counterpart commonly in 16‐bit GB or BIG‐5. This difference makes direct application of English‐based text manipulation programming languages to Chinese erroneous, e.g. application of Icon to reverse a string of Chinese characters. In this paper, a new dialect of Icon, referred to as Chicon (i.e. Chinese Icon), is proposed. In the design of Chicon, new data types were introduced to differentiate pure English and English/Chinese mixed texts. In addition, existing Icon text manipulation functions were modified to account for Chinese texts. Experiments have shown that Chicon not only could overcome the problems of Chinese processing in Icon, but its execution speed was actually superior to Icon in handling Chinese. Furthermore, application of Chicon to a real sized problem, namely word segmentation, has proved that the language is practical. © 1998 John Wiley & Sons, Ltd.
Uncovering Capgras delusion using a large-scale medical records database

Background Capgras delusion is scientifically important but most commonly reported as single case studies. Studies analysing large clinical records databases focus on common disorders but none have investigated rare syndromes. Aims Identify cases of Capgras delusion and associated psychopathology, demographics, cognitive function and neuropathology in light of existing models. Method Combined computational data extraction and qualitative classification using 250 000 case records from South London and Maudsley Clinical Record Interactive Search (CRIS) database. Results We identified 84 individuals and extracted diagnosis-matched comparison groups. Capgras was not ‘monothematic’ in the majority of cases. Most cases involved misidentified family members or close partners but others were misidentified in 25% of cases, contrary to dual-route face recognition models. Neuroimaging provided no evidence for predominantly right hemisphere damage. Individuals were ethnically diverse with a range of psychosis spectrum diagnoses. Conclusions Capgras is more diverse than current models assume. Identification of rare syndromes complements existing ‘big data’ approaches in psychiatry.
Media violence use as a risk factor for aggressive behaviour in adolescence

Whether exposure to violence in the virtual reality of the media has an impact on users’ aggressive behaviour has been a controversial issue in academic as well as public debate. This article summarises a programme of research conducted with adolescents in Germany that presents cross-sectional and longitudinal evidence for the association between violent media use and aggression. It provides experimental evidence in support of mediating variables, such as hostile attributional style, increased normative acceptance of aggression, and emotional desensitisation, which might explain the pathways from media violence use to aggression. In addition it presents the development and experimental evaluation of a theory-based intervention designed to reduce media violence use and decrease its link with aggressive behaviour. The findings are discussed in the context of a large international body of research that points to the causal role of violent media use as a risk factor for aggressive behaviour.