Miracle-dz/UniFAR-FTUs huggingface dataset:
Star–disc (mis-)alignment in Rho Oph and Upper Sco: insights from spatially resolved disc systems with K2 rotation periods

The discovery of close in, giant planets (hot Jupiters) with orbital angular momentum vectors misaligned with respect to the rotation axis of their host stars presents problems for planet formation theories in which planets form in discs with angular momentum vectors aligned with that of the star. Violent, high eccentricity migration mechanisms purported to elevate planetary orbits above the natal disc plane predict populations of proto-hot Jupiters which have not been observed with Kepler. Alternative theories invoking primordial star-disc misalignments have recently received more attention. Here, the relative alignment between stars and their protoplanetary discs is assessed for the first time for a sample of 20 pre-main-sequence stars. Recently published rotation periods derived from high quality, long duration, high cadence K2 light curves for members of the $\rho$ Ophiuchus and Upper Scorpius star forming regions are matched with high angular resolution observations of spatially resolved discs and projected rotational velocities to determine stellar rotation axis inclination angles which are then compared to the disc inclinations. Ten of the fifteen systems for which the stellar inclination could be estimated are consistent with star-disc alignment while five systems indicate potential misalignments between the star and its disc. The potential for chance misalignment of aligned systems due to projection effects and characteristic measurement uncertainties is also investigated. While the observed frequency of apparent star-disc misalignments could be reproduced by a simulated test population in which 100% of systems are truly aligned, the distribution of the scale of inferred misalignment angles could not.
The FSVS Cluster Catalogue: Galaxy Clusters and Groups in the Faint Sky Variability Survey

We describe a large sample of 598 galaxy clusters and rich groups discovered in the data of the Faint Sky Variability Survey (FSVS). The clusters have been identified using a fully automated, semiparametric technique based on a maximum likelihood approach applied to Voronoi tessellation, and enhanced by colour discrimination. The sample covers a wide range of richness, has a density of ∼28 clusters deg -2 , and spans a range of estimated redshifts of 0.05 0.6, the catalogue contributes substantially to the current total of optically selected, intermediate-redshift clusters, and complements the existing, usually X-ray selected, samples. The FSVS fields are accessible for observation throughout the whole year, making them particularly suited for large follow-up programmes. The construction of this FSVS Cluster Catalogue completes a fundamental component of our continuing programmes to investigate the environments of quasars and the chemical evolution of galaxies. We publish here the list of all clusters with their basic parameters, and discuss some illustrative examples in more detail. The full FSVS Cluster Catalogue, together with images and lists of member galaxies etc., will be issued as part of the 'NOAO (National Optical Astronomy Observatories) data products', and accessible at http://www.noao. edu/dpp/. We describe the format of these data and access to them.
The effective permeability of a random medium

The authors investigate the effective permeability of a heterogeneous random medium by numerical simulation and by self-consistent perturbation theory for a class of models including the log-normal model. For a reasonable range of parameters they find close agreement between the simulation and the perturbative calculation. This suggests that both methods may be useful for appropriate models. However, the simulation approach is widely applicable in circumstances where a perturbation calculation is not possible.
Hamiltonian Simulation in the Interaction Picture

We present a low-space overhead simulation algorithm based on the truncated Dyson series for time-dependent quantum dynamics. This algorithm is applied to simulating time-independent Hamiltonians by transitioning to the interaction picture, where some portions are made time-dependent. This can provide a favorable complexity trade-off as the algorithm scales exponentially better with derivatives of the time-dependent component than the original Hamiltonian. We show that this leads to an exponential improvement in gate complexity for simulating some classes of diagonally dominant Hamiltonian. Additionally we show that this can reduce the gate-complexity scaling for simulating $N$-site Hubbard models for time $t$ with arbitrary long-range interactions as well as reduce the cost of quantum chemistry simulations within a similar-sized plane-wave basis to $\widetilde{\mathcal{O}}(N^2t)$ from $\widetilde{\mathcal{O}}(N^{11/3}t)$. We also show a quadratic improvement in query complexity for simulating sparse time-dependent Hamiltonians, which may be of independent interest.
A systematic review of eHealth modes in preventing sexually transmitted infections

Prevention of sexually transmitted diseases (STDs) is critical. Despite developing treatment and prevention programs, sexually transmitted infections (STIs) are essential in developing acute and chronic diseases. Because “eHealth” (electronic-Health) has excellent potential for disseminating health information to the public regarding STDs, we aimed to identify and review all published articles focusing on preventing STIs. After constructing the design and answering population, intervention, comparison, and outcome questions, two authors conducted a systematic literature search in four online databases in January 2022. The screening process and data extraction were conducted by two authors independently, and then, a quality assessment was performed. After removing duplicates, and two rounds of shortlisting, 16 articles were included for data extraction out of 5113 entries. Included studies were of different designs and assessed six preventive outcomes categories, with condom use being the most frequent result among studies. We also extracted implementation outcomes and reviewed them. Included studies with 13,137 participants have provided reasonable evidence of the effectiveness of different types of eHealth in improving STI prevention interventions. Although this systematic review was not without limitations, it can no longer be ignored that eHealth modes offer many opportunities to prevent STDs, especially among the young population.
Low Latency Energy-Efficient Neural Decoders for Block Codes

Neural decoders are being explored for 5G and beyond communication networks which have ultra-low-latency and energy-efficiency requirements. We consider several ultra-short linear and non-linear block codes and design neural decoders for them, which (i) provide near maximum-likelihood (ML) performance in terms of bit and block error rates, and (ii) have low decoding complexity (and hence, latency and energy consumption) in terms of the number of hidden layers and hidden nodes. We explore (i) single-label, (ii) multi-label, and (iii) concatenated coding based decoders. We find that single-label decoders with a single hidden layer having a sufficient number of nodes achieve near-ML performance. Since the number of output nodes required in single-label decoders is exponential in the message length, we investigate a multi-label neural decoder requiring a significantly lower number of output nodes but having decreased performance in terms of block error rate. To eliminate extra errors, we concatenate an outer code with the original code as the inner code. The inner and outer codes are decoded by multi-label and single-label neural decoders, respectively, leading to better block error performance than that is achievable using multi-label decoders.
Reflection symmetry at a B=0 metal-insulator transition in two dimensions

We report a remarkable symmetry between the resistivity and conductivity on opposite sides of the B=0 metal-insulator transition in a two-dimensional electron gas in high-mobility silicon metal-oxide-semiconductor field-effect transistors. This symmetry implies that the transport mechanisms on the two sides are related. {copyright} {ital 1997} {ital The American Physical Society}
Peripheral Ion Channel Genes Screening in Painful Small Fiber Neuropathy

Neuropathic pain is a characteristic feature of small fiber neuropathy (SFN), which in 18% of the cases is caused by genetic variants in voltage-gated sodium ion channels. In this study, we assessed the role of fifteen other ion channels in neuropathic pain. Patients with SFN (n = 414) were analyzed for ANO1, ANO3, HCN1, KCNA2, KCNA4, KCNK18, KCNN1, KCNQ3, KCNQ5, KCNS1, TRPA1, TRPM8, TRPV1, TRPV3 and TRPV4 variants by single-molecule molecular inversion probes–next-generation sequencing. These patients did not have genetic variants in SCN3A, SCN7A-SCN11A and SCN1B-SCN4B. In twenty patients (20/414, 4.8%), a potentially pathogenic heterozygous variant was identified in an ion-channel gene (ICG). Variants were present in seven genes, for two patients (0.5%) in ANO3, one (0.2%) in KCNK18, two (0.5%) in KCNQ3, seven (1.7%) in TRPA1, three (0.7%) in TRPM8, three (0.7%) in TRPV1 and two (0.5%) in TRPV3. Variants in the TRP genes were the most frequent (n = 15, 3.6%), partly in patients with high mean maximal pain scores VAS = 9.65 ± 0.7 (n = 4). Patients with ICG variants reported more severe pain compared to patients without such variants (VAS = 9.36 ± 0.72 vs. VAS = 7.47 ± 2.37). This cohort study identified ICG variants in neuropathic pain in SFN, complementing previous findings of ICG variants in diabetic neuropathy. These data show that ICG variants are central in neuropathic pain of different etiologies and provides promising gene candidates for future research.
A Generalized Form of Lait's Modified Potential Vorticity

Abstract Ertel's potential vorticity P is in widespread use as a diagnostic of dynamical processes in the stratosphere. For a variety of applications, however, the exponential increase of P with altitude is problematic. For this reason, Lait proposed a modified potential vorticity ΠL, where a physically meaningful scaling is introduced that removes much of the altitude dependence of P. Here a generalized form of ΠL is proposed by introducing an additional degree of freedom in the scaling. This generalized modified potential vorticity Πg possesses the same conservation properties as ΠL itself and as the classic potential vorticity P but can be adjusted more closely to the specific situation under investigation. Comparison, over a large altitude range in the stratosphere, of fields of Πg with dynamical measures of the polar vortex edge and with observations of the long-lived trace gas N2O shows that Πg constitutes a more intuitively interpretable quantity than ΠL.
The coincidence approach to stochastic point processes

The structure of the probability space associated with a general point process, when regarded as a counting process, is reviewed using the coincidence formalism. The rest of the paper is devoted to the class of regular point processes for which all coincidence probabilities admit densities. It is shown that their distribution is completely specified by the system of coincidence densities. The specification formalism is stressed for ‘completely’ regular point processes. A construction theorem gives a characterization of the system of coincidence densities of such a process. It permits the study of most models of point processes. New results on the photon process, a particular type of conditioned Poisson process, are derived. New examples are exhibited, including the Gauss-Poisson process and the ‘fermion’ process that is suitable whenever the points are repulsive.
Assessing Productivity Channels of Human Capital in the Southern African Development Community: New Insights from Women’s Empowerment

There is massive and growing volume of literature on human capital and productivity. However, there is little emphasis on the growth channels of human capital, particularly on women’s empowerment, despite its theoretical underpinning and relevance in the Southern African Development Community (SADC). Understanding the effective channels of human capital is essential for policymakers in promoting sustainable growth and improved welfare. Given this, the study examines the effect of women’s empowerment through the ‘factor accumulation channel’ and the ‘productivity channel’ on SADC using cross-sectionally augmented autoregressive distributed lag (CS-ARDL) and the Dumitrescu–Hurlin non-causality test. Evidence from short- and long-run effects using the CS-ARDL shows that the factor accumulation and productivity channels of women’s empowerment have not benefited productivity growth in the SADC, although causality flows from the human capital indicators to productivity growth. The vital way for policy to boost productivity in SADC is to improve investment in female education and ensure that human capital is appropriately distributed and matches the economy’s dynamic demands. Based on the findings, the study suggests developing a framework to ascertain from time to time the marginal benefits of investment in female education compared to the marginal costs, both at the levels of the factor accumulation channel and the productivity channel in SADC.
Electron spin dynamics and hyperfine interactions in Fe Al0.1Ga0.9As GaAs spin injection heterostructures

We have studied hyperfine interactions between spin-polarized electrons and lattice nuclei in Al_0. 1Ga_0. 9As/GaAs quantum well (QW) heterostructures. The spin-polarized electrons are electrically injected into the semiconductor heterostructure from a metallic ferromagnet across a Schottky tunnel barrier. The spin-polarized electron current dynamically polarizes the nuclei in the QW, and the polarized nuclei in turn alter the electron spin dynamics. The steady-state electron spin is detected via the circular polarization of the emitted electroluminescence. The nuclear polarization and electron spin dynamics are accurately modeled using the formalism of optical orientation in GaAs. The nuclear spin polarization in the QW is found to depend strongly on the electron spin polarization in the QW, but only weakly on the electron density in the QW. We are able to observe nuclear magnetic resonance (NMR) at low applied magnetic fields on the order of a few hundred Oe by electrically modulating the spin injected into the QW. The electrically driven NMR demonstrates explicitly the existence of a Knight field felt by the nuclei due to the electron spin.
Academic achievements and brain volume development in children and adolescents

Abstract Children are expected to acquire both basic and numeric skills. Achievement of higher levels of reading, writing, arithmetic, and vocabulary are favorable and desirable. The relationship between each literacy skill and neural development has been investigated; however, association between brain development and the 4 literacy skills has not been examined. This longitudinal, structural, neuroimaging study explored the contribution of higher academic achievement in reading, writing, arithmetic, and vocabulary to neural development. The brain volumes of children and adolescents aged 9–16 years were measured in the first test. Approximately 2.6 years later, the brain volumes and 4 academic achievement scores of 77 participants were measured in the second test. Changes in the gray matter volume in the left fusiform gyrus were associated with vocabulary scores, whereas those in the left striatum were associated with arithmetic scores. The reading and writing scores showed no statistically significant relationship with changes in brain volume. The current vocabulary score correlated with current gray matter volume, while brain volumes in the first test showed no association with any achievement scores. These results suggest that academic achievement may modulate brain plasticity in various ways.
X-Ray Emission of Markarian 421: New Clues from Its Spectral Evolution. I. Temporal Analysis

Mrk 421 was repeatedly observed with BeppoSAX in 1997 and 1998. This is the first of two papers where we present the results of a thorough temporal and spectral analysis of all the data available to us, focusing in particular on the flare of 1998 April, which was simultaneously observed also at TeV energies. Here we focus on the time analysis, while the spectral analysis and physical interpretation are presented in the companion paper. The detailed study of the flare in different energy bands reveals very important new results: (1) hard photons lag the soft ones by 2-3 ks—a behavior opposite to what is normally found in high-energy peak BL Lac X-ray spectra; (2) the flare light curve is symmetric in the softest X-ray band, while it becomes increasingly asymmetric at higher energies, with the decay being progressively slower than the rise; and (3) the flux decay of the flare can be intrinsically achromatic if a stationary underlying emission component is present. The temporal and spectral information obtained challenge the simplest models currently adopted for the (synchrotron) emission and most importantly provide clues on the particle acceleration process.
Pulse shaping using dispersion-engineered difference frequency generation

The temporal-mode (TM) basis is a prime candidate to perform high-dimensional quantum encoding. Quantum frequency conversion has been employed as a tool to perform tomographic analysis and manipulation of ultrafast states of quantum light necessary to implement a TM-based encoding protocol. While demultiplexing of such states of light has been demonstrated in the Quantum Pulse Gate (QPG), a multiplexing device is needed to complete an experimental framework for TM encoding. In this work we demonstrate the reverse process of the QPG. A dispersion-engineered difference frequency generation in non-linear optical waveguides is employed to imprint the pulse shape of the pump pulse onto the output. This transformation is unitary and can be more efficient than classical pulse shaping methods. We experimentally study the process by shaping the first five orders of Hermite-Gauss modes of various bandwidths. Finally, we establish and model the limits of practical, reliable shaping operation.
A New Fokker–Planck Approach for the Relaxation-driven Evolution of Galactic Nuclei

We present an approach for simulating the collisional evolution of spherical isotropic stellar systems based on the one-dimensional Fokker–Planck equation. A novel aspect is that we use the phase volume as the argument of the distribution function instead of the traditionally used energy, which facilitates the solution. The publicly available code PhaseFlow implements a high-accuracy finite-element method for the Fokker–Planck equation, and can handle multiple-component systems, optionally with the central black hole and taking into account loss-cone effects and star formation. We discuss the energy balance in the general setting, and in application to the Bahcall–Wolf cusp around a central black hole, for which we derive a perturbative solution. We stress that the cusp is not a steady-state structure, but rather evolves in amplitude while retaining an approximately density profile. Finally, we apply the method to the nuclear star cluster of the milky Way, and illustrate a possible evolutionary scenario in which a two-component system of lighter main-sequence stars and stellar-mass black holes develops a Bahcall–Wolf cusp in the heavier component and a weaker cusp in the lighter, visible component, over the period of several Gyr. The present-day density profile is consistent with the recently detected mild cusp inside the central parsec, and is weakly sensitive to initial conditions.
Can the relativistic light bending model explain X-ray spectral variations of Seyfert galaxies?

Many Seyfert galaxies are known to exhibit Fe-K broad emission line features in their X-ray energy spectra. The observed lines have three distinct features; (1) the line profiles are skewed and show significant low-energy tails, (2) the Fe-K band have low variability, which produces a broad and deep dip in the root-mean-square (rms) spectra, and (3) photons in this band have time lags behind those in the adjacent energy bands with amplitudes of several $R_g/c$, where $R_g$ is the gravitational radius. The "relativistic light bending model" is proposed to explain these observed features, where a compact X-ray source (lamp post) above an extreme Kerr black hole illuminates the innermost area of the accretion disc. In this paper, we critically examine the relativistic light bending model by computing the rms spectra and the lag features using a ray-tracing technique, when a lamp post moves vertically on the black hole spin axis. As a result, we found that the observed deep rms dip requires that the iron is extremely overabundant ($\gtrsim10$ solar), whereas the observed lag amplitude is consistent with the normal iron abundance. Furthermore, disappearance of the lag in the high-flux state requires a source height as high as $\sim40\,R_g$, which contradicts the relativistically broad emission line feature. Our simulations agree with the data that the reverberation feature moves to lower frequencies with larger source height, however, if this scenario is correct, the simulations predict detection of a clear Fe-K lag at low frequencies, which is not constrained in the data. Therefore, we conclude that the relativistic light bending model may not explain the characteristic Fe-K spectral variations in Seyfert galaxies.
The role of interior design in promoting a sense of home in people with dementia living in care facilities

Abstract With the introduction of the person-centred dementia care model, the interior design of care facilities has increasingly emphasised the need to make people with dementia (PWD) feel at home. The sense of home can improve the quality of life after relocating to long-term care facilities. However, the effectiveness of the current design approach is debatable because it ignores the intrinsic meaning of home. Therefore, the purpose of this study is to propose a new design approach to interior design that brings a sense of home to PWDs through the intrinsic meaning of home. It first defines the intrinsic meaning of home as an ‘intimate relationship’ between people and space, and then proposes a hypothesis that PWDs can re-establish this relationship through bodily habits. The ethnographic case studies verified it and explained how the interior environment influences it. Finally, based on the previous findings, this research develops the design framework and design guidelines.
Implications of Fragment-Based Drug Discovery in Tuberculosis and HIV

Tuberculosis (TB) remains a global health problem and the emergence of HIV has further worsened it. Long chemotherapy and the emergence of drug-resistance strains of Mycobacterium tuberculosis as well as HIV has aggravated the problem. This demands urgent the need to develop new anti-tuberculosis and antiretrovirals to treat TB and HIV. The lack of diversity in drugs designed using traditional approaches is a major disadvantage and limits the treatment options. Therefore, new technologies and approaches are required to solve the current issues and enhance the production of drugs. Interestingly, fragment-based drug discovery (FBDD) has gained an advantage over high-throughput screenings as FBDD has enabled rapid and efficient progress to develop potent small molecule compounds that specifically bind to the target. Several potent inhibitor compounds of various targets have been developed using FBDD approach and some of them are under progression to clinical trials. In this review, we emphasize some of the important targets of mycobacteria and HIV. We also discussed about the target-based druggable molecules that are identified using the FBDD approach, use of these druggable molecules to identify novel binding sites on the target and assays used to evaluate inhibitory activities of these identified druggable molecules on the biological activity of the targets.