Miracle-dz/UniFAR-FTUs huggingface dataset:
in a large

Large and rare copy number variants (CNVs) at several loci have been shown to increase risk for schizophrenia. Aiming to discover novel susceptibility CNV loci, we analyzed 6882 cases and 11 255 controls genotyped on Illumina arrays, most of which have not been used for this purpose before. We identiﬁed genes enriched for rare exonic CNVs among cases, and then attempted to replicate the ﬁndings in additional 14 568 cases and 15 274 controls. In a combined analysis of all samples, 12 distinct loci were enriched among cases with nominal levels of signiﬁcance ( P < 0.05); however, none would survive correction for multiple testing. These loci include recurrent deletions at 16p12.1, a locus previously associated with neurodevelopmental disorders ( P 5 0.0084 in thediscoverysampleand P 5 0.023inthe replication sample). Otherplausiblecandidatesincludenon-recurrent deletions at the glutamate transporter gene SLC1A1, a CNV locus recently suggested to be involved in schizophrenia through linkage analysis, and duplications at 1p36.33 and CGNL1 . A burden analysis of large ( > 500 kb), rare CNVs showed a1.2% excess incases after excluding known schizophrenia-associated loci, suggesting that additional susceptibility loci exist. However, even larger samples are required for their discovery.
Rowan Digital Works Rowan Digital Works

In this paper, we review applications of covariance-based structural equation modeling (SEM) in the Journal of Advertising (JA) starting with the first issue in 1972. We identify 111 articles from the earliest application of SEM in 1983 through 2015, and discuss important methodological issues related to the following aspects: confirmatory factor analysis (CFA), causal modeling, multiple group analysis, reporting, and guidelines for interpretation of results. Moreover, we summarize some issues related to varying terminology associated with different SEM methods. Findings indicate that the use of SEM in the JA contributes greatly to conceptual, empirical, and methodological advances in advertising research. The assessment contributes to the literature by offering advertising researchers a summary guide to best practices and reminds of the basics that distinguish the powerful and unique approach involving structural analysis of covariances.
Internal Dynamics and Boundary Forcing Characteristics Associated with Interannual Variability of the Asian Summer Monsoon

In this paper, we present a description of the internal dynamics and boundary forcing characteristics of two major components of the Asian summer monsoon (ASM), i.e., the South Asian (SAM) and the Southeast-East Asian monsoon (SEAM). The description is based on a new monsoon-climate paradigm in which the variability of ASM is considered as the outcome of the interplay of a "fast" and an "intermediate" monsoon subsystem, under the influenced of the "slow" varying external forcings. Two sets of regional monsoon indices derived from dynamically consistent rainfall and wind data are used in this study. For SAM, the internal dynamics is represented by that of a "classical" monsoon system where the anomalous circulation is governed by Rossby-wave dynamics, i.e., generation of anomalous vorticity induced by an off-equatorial heat source is balanced by planetary vorticity advection. On the other hand, the internal dynamics of SEAM is characterized by a "hybrid" monsoon system featuring multi-cellular meridional circulation over the East Asian section, extending from the deep tropics to midlatitudes. These meridional-cells link tropical heating to extratropical circulation system via the East Asian jetstream, and are responsible for the characteristic occurrences of zonally oriented anomalous rainfall patterns over East Asian and the subtropical western Pacific. In the extratropical regions, the major upper level vorticity balance is by anomalous vorticity advection and generation by the anomalous divergent circulation. A consequence of this is that compared to SAM, the SEAM is associated with stronger teleconnection patterns to regions outside the ASM. A strong SAM is linked to basin-scale sea surface temperature (SST) fluctuation with significant signal in the equatorial eastern Pacific. During the boreal spring SST warming in the Arabian Sea and the subtropical western Pacific may lead to a strong SAM. For SEAM, interannual variability is tied to SSTA over the Sea of Japan and the South China Sea regions, while the linkage to equatorial basin-scale SSTA is weak at best. A large scale SSTA dipole with warming (cooling) in the subtropical central (eastern) Pacific foreshadows a strong SEAM.
Path Constraints from a Modal Logic Point of View (Extended Abstract)

We analyze several classes of path constraints for semistructured data in a uni-ﬁed framework and prove some decidability and complexity results for these constraints by embedding them in Propositional Dynamic Logic. While some of our decidability results were known before, we believe that our improved complexity bounds are new. Our proofs, based on techniques from modal logic, shed additional light on the reasons for previously known decidability and complexity results.
Phase Behaviour of a Near-Critical Gas Condensate Reservoir Fluid from a Conventional Field in the Niger-Delta Region

Near-critical gas condensate reservoir fluid like near-critical oil has a very complex hydrocarbon phase behavior and is likely to be encountered as deeper formations are been drilled in an extensive search for hydrocarbon deposits. This paper presents an experimental methodology and results of a PVT analysis done on two (2) near-critical gas condensate reservoir fluids from a prolific gas field in the Niger Delta region. The following experiments: Constant Composition expansion (CCE), single stage flash and reservoir fluid composition were carried out using a HPHT visual PVT cell and gas chromatograph. The CCE test performed clearly showed the unusual but unique formation of two liquid phases rather than one liquid phase during the isothermal depressurization below the dew point pressure and the subsequent disappearance of the lower liquid phase, the maximum liquid drop out (LDO) behavior (above 45% condensate dropout) at a small pressure drop of 100-150 psig below the dew point pressure owing to the fact that at the vicinity of the critical point, a marginal change in pressure caused a rapid volumetric change in the single-phase gas. The C 7+ mole percent (<12.5%) and the produced gas-oil ratio (>5,000 SCF/STB) were other parameters used to further provide a reasonable insight that the fluid under study is a near-critical gas condensate. In conclusion, proper characterization of a near-critical gas condensate reservoir fluid will greatly aid the reservoir and production engineers to have a better and more robust field development strategy to produce and manage a near-critical gas condensate reservoir.
Statistica Sinica Preprint

We present a reparameterization of vector autoregressive moving average (VARMA) models that allows parameter estimation under the constraints of causality and invertibility. This reparameterization is accomplished via a bijection from the complicated causal-invertible parameter space to Euclidean space. The bijection facilitates computation of maximum likelihood estimators (MLE) via unconstrained optimization, as well as computation of Bayesian estimates via prior speciﬁcation on the constrained space. The proposed parameterization is connected to the Schur-stability of polynomials and the associated Stein transformation, which are often used in dynamical systems; we establish a fundamental characterization of Schur stable polynomials via a novel characterization of positive deﬁnite block Toeplitz matrices. Our results also generalize some classical results in dynamical systems. Maximum likelihood estimation is done using the optim L-BFGS-B function in R. The initial values of the pre-parameters are chosen to be those calculated from the Yule-Walker estimate. We use
New, Improved Bulk-microphysical Schemes for Studying Precipitation Processes in WRF. Part 1; Comparisons with Other Schemes

An improved bulk microphysical parameterization is implemented into the Weather Research and Forecasting (WRF) model. This bulk microphysical scheme has three different options, 21CE (cloud ice & snow), 3ICE-graupel (cloud ice, snow & graupel) and 3ICE-hail (cloud ice, snovv & hail). High-resolution model simulations are conducted to examine the impact of microlphysical schemes on two different weather events (a midlatitude linear convective system and an Atlantic hurricane). In addition, the improved "shemes are compared with WRF's three other bulk microphysical schemes. The results suggest that microphysics has a major impact on the organization and precipitation processes associated with a summer midlatitude convective line system. The 31CE scheme with a cloud ice-snow-hail configuration led to a better agreement with observation in terms of simulated narrow convective line and rainfall intensity. This is because the 3ICE-hail scheme includes dense ice precipitating (hail) particle with very fast fall speed (over 10 m s-I). For an Atlantic hurricane case, varying the microphysical schemes had no significant impact on the track forecast but did affect the intensity (important for airsea interaction). The vertical distributions of model simulated cloud species (i.e., snow) are quite sensitive to microphysical schemes, which is an important issue for future verification against satellite retrievals. Sensitivity tests are performed to identify that snow productions could ble increased by increasing the snow intercept, turning off the auto-conversion from snow bo graupel and reducing the transfer processes from cloud-sized particles to precipitation-sized ice.
The effect of perceived organizational support on thetransfer of training outcomes to the workplace

Transfer of training refers to the consistent application of the knowledge, skills and attitudes that are learned from training to the workplace. The success of transfer of training is influenced by many factors including the work environment. However, to date the influence of the social exchange factor in the workplace, known as perceived organizational support, on transfer of training has not been adequately explored. This study has been conducted to addresses this gap. Specifically, this study explores the moderating effect of perceived organizational support on the relationship between learning and transfer of training. The data of this study has been collected from two sources, the employees and their supervisors through surveys. The data was analyzed using structural equation modeling approach. The findings reveal that perceived organizational support has an important role as a predictor to transfer of training but not as a moderator as proposed in this study.
A modified Hilbert fractal resonator based rectenna design for GSM900 band RF energy harvesting applications

This article proposes a novel rectenna design based on modified Hilbert fractal shaped microstrip antenna and Villard voltage doubler rectifying circuit for RF energy harvesting applications operating at Global System for Mobile Communications (GSM) 900 MHz band. The energy harvesting antenna is numerically optimized and fabricated on a Rogers RO4003 substrate of thickness 1.52 mm with a compact overall physical sizes of 80 mm × 82 mm (λ0/4.16 × λ0/4.06). Various geometric parameters and circuit component values of the proposed energy harvesting system are optimized in order to achieve a matched input impedance with good radiation performance of high gain for the input power level less than −20 dBm. The numerical and experimental results point out the technical potential of the proposed rectenna design to be utilized in DC power supply modules of low voltage, low power electronic devices.
All Digital ON Chip Process Sensor Using Ratioed Inverter Based Ring Oscillator

In this project, an all-digital ON-chip process sensor using a ratioed inverter-based ring oscillator is proposed. Two types of the ratioed inverter-based ring oscillators, nMOS and pMOS types are proposed to sense process variation. The nMOS (pMOS)-type ring oscillator is designed to improve its sensitivity to the process variation in the nMOS (pMOS) transistors using the ratioed inverter that consists of only nMOS (pMOS) transistors. A compact process sensor can be realized using only these two types of ring oscillators.
Efficacy of Antiseptic-Impregnated Central Venous Catheters in Preventing Catheter-Related Bloodstream Infection

CENTRAL VENOUS CATHETERS ARE commonly used for parenteral nutrition and fluid or drug administration in a variety of hospital settings. While providing convenient and beneficial venous access, these catheters also increase the risk of nosocomial bloodstream infection, contributing to the more than 200 000 cases that occur annually in the United States. Catheter-related bloodstream infection (CRBSI) can be a serious complication, leading to increases in mortality, hospital stay, and medical costs. A variety of methods have been used to prevent catheter-related infections. Aseptic insertion techniques and proper cathetercarehaveprovedeffective,whilesilvercoatedcathetercuffshaveproducedmixed results. Recently, the use of antibioticcoated and antiseptic-impregnated catheters toreduce the incidenceofCR-BSIhas been evaluated. Examples of the antibiotics that have been used to coat catheters include cefazolin and minocyclinerifampin. Although antibiotic-coated cathetersshowpromiseclinically, thetechnical requirements forcoating thecatheter and concerns of antibiotic resistance may limit their widespread use. Catheters impregnated with the combination antiseptic chlorhexidine–silver sulfadiazinedonot require coatingbefore insertion and may be less susceptible to antibiotic resistance. Several recent randomized trials have assessed the efficacy of these catheters in reducing catheter colonization and CR-BSI. Although most of the studies have shown a significant reduction in catheter colonization, only 1 study has shown a significant reduction in the clinically more important AuthorAffiliations: DepartmentsofPharmacy(DrsVeenstra and Sullivan), Medicine (Drs Saint and Saha), Biostatistics (Dr Lumley), and Health Services (Dr Sullivan), University of Washington, Seattle. Dr Saint is now with the University of Michigan Medical Center, Ann Arbor. Financial Disclosure: None of the authors has received financial support from or holds any personal financial interest in the manufacturer of Arrowguard chlorhexidine–silver sulfadiazine–impregnated catheters, Arrow International, Reading, Pa. Corresponding Author and Reprints: David L. Veenstra, PharmD, PhD, University of Washington School of Pharmacy, PO Box 357630, Seattle, WA 981957630 (e-mail: veenstra@u.washington.edu). Context Central venous catheters impregnated with chlorhexidine and silver sulfadiazine have recently been introduced for the prevention of catheter-related infections. However, there remains some uncertainty regarding the efficacy of these catheters because of conflicting reports in the literature.
Mythicomycetaceae fam. nov. (Agaricineae, Agaricales) for accommodating the genera Mythicomyces and Stagnicola, and Simocybe parvispora reconsidered

The analysis of a combined dataset including 5.8S (ITS) rDNA, 18S rDNA, 28S rDNA, and rpb2 data from species of the Agaricineae (Agaricoid clade) supports a shared monophyletic origin of the monotypic genera Mythicomyces and Stagnicola. The new family Mythicomycetaceae, sister to Psathyrellaceae, is here proposed to name this clade, which is characterised, within the dark-spored agarics, by basidiomata with a mycenoid to phaeocollybioid habit, absence of veils, a cartilaginous-horny, often tapering stipe, which discolours dark brown towards the base, a greyish brown, pale hazel brown spore deposit, smooth or minutely punctate-verruculose spores without a germ pore, cheilocystidia always present, as metuloids (thick-walled inocybe-like elements) or as thin-walled elements, pleurocystidia, when present, as metuloids, pileipellis as a thin ixocutis without cystidioid elements, clamp-connections present everywhere, and growth on wood debris in wet habitats of boreal, subalpine to montane coniferous forests. Simocybe parvispora from Spain (two collections, including the holotype), which clusters with all the sequenced collections of Stagnicola perplexa from Canada, USA, France and Sweden, must be regarded as a later synonym of the latter.
Proliferative human cell sources applied as biocomponent in bioartificial livers: a review

Introduction: Bioartificial livers (BALs) are urgently needed to bridge severe liver failure patients to liver transplantation or liver regeneration. When based on primary hepatocytes, their efficacy has been shown in animal experiments and their safety was confirmed in clinical trials. However, a proliferative human cell source with therapeutic functionality is needed to secure availability and move BAL application forward. Areas covered: This review compares the performance of BALs based on proliferative human biocomponents and primary hepatocytes. This review evaluates relevant studies identified by searching the MEDLINE database until July 2011 and some of our own unpublished data. Expert opinion: All the discussed hepatocyte-like biocomponents show deficiencies in their hepatic functionality compared with primary hepatocytes, particularly functions occurring late in liver development. Nonetheless, the HepaRG, HepG2-GS-CYP3A4, and mesenchymal stem cells show efficacy in a statistically well-powered animal model of acute liver failure, when applied in a BAL device. Various methods to gain higher functionality of BALs, including genetic modification, the usage of combinatory cell sources, and improvement of culture methods, have scarcely been applied, but may further pave the path for BAL application. Clinical implementation of a BAL based on a human proliferative biocomponent is still several years away.
Verification of recovery of distribution density function of the random variable by methods of nonparametric statistics

The paper considers an algorithm of recovery of distribution density function of a random variable by methods of nonparametric statistics. For samples of various length (from 20 to 2000) of normal distribution the quantile estimates of a random variable are calculated by methods of parametrical and nonparametric statistics. It is established that errors of the quantile estimates obtained by parametrical and nonparametric methods are values of the same order.
Active Animations of Reduced Deformable Models with Environment

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Commotio Retinae

History of Present Illness A 29-year-old man was referred after sustaining a head injury during an altercation. He lost consciousness during the event, and when he awoke he reported an inability to see out of his left eye. He was evaluated at a local emergency department and was noted to have periorbital ecchymosis in addition to an inferior orbital wall fracture seen on head imaging. He was transferred to the University of Iowa for further evaluation.
DETECTING SUGARCANE DISEASES THROUGH ADAPTIVE DEEP LEARNING MODELS

Sugarcane diseases are a major threat in the sugarcane industry which leads to the vast destruction of disease-ridden crops, decreases farming, and large financial loss on small-scale farmers. The loss and farming disaster can be prevented if the early detection of such diseases can be detected and applying new technologies such as machine learning technology is implemented. Subsequently, deep learning is a current technology in machine learning that delivers a process to manage with these dilemmas. The research manuscript intends to integrate and train various models of CNN architecture using a sugarcane image dataset containing 20,000 of disease infected and non-infected sugarcane leaves. There are five trained models used in the study, these are StridedNet, AlexNet, LeNet, VGGNet, and GoogleNet. The VGGNet model achieves the highest accuracy rate of 95% and GoogleNet achieves the lowest rate of 65% among the trained models. The trained CNN models are capable in detecting and class ifying sugarcane leaf images to disease infected and non-infected class based on the outlines of the leaves. Early detection of sugarcane diseases through deep learning models could help farmers sustain their production and income.
GEOMETRIC ANALYSIS

During my graduate study, I was rather free in picking research topics. I [538] worked on fundamental groups of manifolds with non-positive curvature. But in the second year of my study, I started to look into differential equations on manifolds. While Chern did not express much opinions on this part of my research, he started to appreciate it a few years later. In fact, after Chern gave a course on Calabi’s works on affine geometry in 1972 in Berkeley, Cheng told me these inspiring lectures. By 1973, Cheng and I started to work on some problems mentioned in his lectures. We did not realize that great geometers Pogorelov, Calabi and Nirenberg were also working on them. We were excited that we solved some of the conjectures of Calabi on improper affine spheres. But soon we found out that Pogorelov [398] published it right before us by different arguments. Nevertheless our ideas are useful to handle other problems in affine geometry and my knowledge about Monge-Ampère equations started to be broadened in these years. Chern was very pleased by my works, especially after I [543] solved the problem of Calabi on Kähler Einstein metric in 1976. I had been in Stanford and Chern proposed to Berkeley Department to hire me. I visited Berkeley in 1977 for a year and gave a course on geometric analysis with emphasis on isometric embedding.
A Comparative Study of Power in Religious Spoken Discourse by American-English and Egyptian-Arabic-Speaking televangelists دراسة مقارنة للقوة في الخطاب الديني الشفهي عند وعاظ من متحدثي الإنجليزية الأمريكية ومتحدثي العربية المصرية

participant power hierarchy of Haig (2012), Cipriani (2002) and Ezeifeka (2013). Statistically-significant differences between the two groups are detected using SPSS 22 nd . Findings illustrate fourteen mechanisms of power manifestation in the data examined. Such strategies as code-switching and using scientific facts are found to be the preference of the American group versus others (e