Miracle-dz/UniFAR-FTUs huggingface dataset:
Kinesin from pig brain studied by electron microscopy.

Kinesin, a protein that transports particles along microtubules, has been purified from pig brain, following published methods. By electron microscopy of both shadowed and negatively stained specimens, it appears to be a rod with a large branched structure at one end and a small fork at the other. The total length of the structure is about 100 nm. The rod has a diameter of 2-4 nm. Close to the middle of the rod there may be a flexible joint. The molecules appear to be attached to microtubules most often by their forked ends in the presence of AMP.PNP. However, the large branched end can also attach to microtubules and individual molecules occasionally have been seen cross-linking two microtubules.
Who is on your sofa?: TV audience communities and second screening social networks

Television viewing coupled with audience interaction through a second screen has gained popularity as second screen capable devices have become more pervasive and affordable. In this paper, we investigate the nature of television audiences which engage in second screen interactions. Two different television show audiences are explored though their message activity while using the Twitter social blogging service. Connections are made between users when retweeting messages or mentioning other users in a message. The networks of viewers which are formed when viewers connect through these means reveal different characteristics within the audience networks and imply that different motivations for second screening while watching television shows are in play.
Asymmetric standing posture after stroke is related to a biased egocentric coordinate system

Background: Weakness and somatosensory deficits have long been known to be involved in the postural instability of subjects with stroke. Recently, it has been shown that impaired representations of the orientation of the longitudinal axis of the body (LBA, egocentric reference) and of verticality (allocentric reference) may also play a role. The objective of the present study was to determine whether these two references were independently linked to postural asymmetry in standing stroke patients. Methods: Twenty-two subjects were tested after a first hemispheric stroke (13 ± 7.5 weeks). The LBA perception was investigated in the supine position by adjusting the orientation of a luminous rod in the frontal plane to correspond to the subjective LBA. The subjective visual vertical (SVV) was assessed by adjusting the orientation of a luminous line in the frontal plane to correspond to the SVV in upright patients. Weight distribution was measured in the standing position for about 2 minutes and 45 seconds by two separate force platforms under the feet. Results: LBA and SVV were strongly associated (r = 0.7; p < 0.001). The estimate of the LBA was a better predictor (r = −0.52: p < 0.02) of weight bearing asymmetry than was SVV (r = −0.41; p = 0.074) when adjusted for motor weakness and hypoesthesia. Conclusion: Contralesional rotation of the longitudinal axis of the body could lead to unequal distribution of loading on the feet. This novel interpretation of weight bearing asymmetry underlines the complexity of control of the erect stance following stroke and brings new perspectives for rehabilitation programs.
Biochemical Markers of Fibrosis for Chronic Liver Disease : Data mining-based Approach Torky

–Staging of liver fibrosis has important implications for disease prognosis and treatment decisions. Knowing the degree of a disease allows a physician to provide specific treatment to the patient leading to better care. The use of serum markers becomes important to predict liver fibrosis. The objective of this work is to build a classification model in the form of a tree structure to predict liver fibrosis stage in patients with chronic hepatitis C genotype 4 in Egypt. In addition, to evaluate whether laboratory examinations can be used to determine the rate of liver fibrosis progression in patients chronically infected with hepatitis C virus (HCV). This paper focuses on the FibroTest which used to stage liver fibrosis to compare the results of the non-invasive markers using histology as reference method, and tried to determine if they could also be used in Egyptian patients. Keywords––Data mining, Decision Trees, Serum Markers, FibroTest; Liver fibrosis, Chronic Liver Disease
Dietary Phytoncide Supplementation Improved Growth Performance and Meat Quality of Finishing Pigs

We conducted this 10-wk experiment to evaluate the effects of dietary phytoncide, Korean pine extract as phytogenic feed additive (PFA), on growth performance, blood characteristics, and meat quality in finishing pigs. A total of 160 pigs ([Landrace×Yorkshire]×Duroc, body weight (BW) = 58.2±1.0 kg) were randomly allocated into 1 of 4 treatments according to their BW and sex, 10 replicate pens per treatment with 4 pigs per pen were used (2 barrows and 2 gilts). Dietary treatments were: CON, control diet; PT2, CON+0.02% PFA; PT4, CON+0.04% PFA; PT6, CON+0.06% PFA. Overall, average daily gain (ADG) was higher in PT4 (p<0.05) than in PT6, average daily feed intake (ADFI) was lower in PT6 than in CON (p<0.05). Besides ADFI decreased linearly (p<0.05) with the increased level of phytoncide and gain:feed ratio in PT4 treatment was higher (p<0.05) than CON treatment. During 5 to 10 weeks and overall, quadratic (p<0.05) effect was observed in ADG among the treatments. At the end of this experiment, pigs fed with PT4 diet had a greater (p<0.05) red blood cell concentration compared to the pigs fed CON diet. Water holding capacity increased linearly (p<0.05) with the increased level of phytoncide supplementation. Moreover, firmness, redness, yellowness, and drip loss at day 3 decreased linearly (p<0.05) with the increase in the level of phytoncide supplementation. In conclusion, inclusion of phytoncide could enhance growth performance without any adverse effects on meat quality in finishing pigs.
Prevention of DDoS and Brute Force Attacks on Web Log Files using Combination of Genetic Algorithm and Feed forward Back Propagation Neural Network

World Wide Web has become an ultimate source of information. Traditional services such as banking, education, medicine, defence, and transportation are being presented by web applications. Whenever the users make use of any web application, all the activities of the users get automatically get appended into the web log files. The web log file data helps the website owners in number of ways such as customization of web content, pre-fetching and caching, E-commerce, etc. However, the web log file data is exposed to number of attacks. In this paper, a new technique has been proposed to prevent the log file data from the two most common attacks: Brute force attack and DDoS attack.
Effect of Intracarotid Papaverine on Human Cerebral Blood Flow and Vascular Resistance During Acute Hemispheric Arterial Hypotension

This study assessed the feasibility of augmenting cerebral blood flow (CBF) and decreasing hemispheric cerebrovascular resistance (CVR) by intracarotid papaverine during acute cerebral hypotension. Awake patients (n = 10) undergoing transfemoral balloon occlusion of an internal carotid artery (ICA) with nitroprusside (SNP)-induced systemic hypotension (10% reduction of mean arterial pressure) were studied. We measured mean femoral artery pressure (MAP), mean distal ICA pressure (P ica), and CBF (intracarotid 133Xe) at two time points: before and after intracarotid papaverine infusion (1 or 7 mg/min). Two patients became symptomatic immediately after ICA occlusion and were excluded. One patient developed a focal seizure during papaverine infusion. In another, the occlusion balloon deflated prematurely. Of the remaining six patients, two of the three patients who received high-dose papaverine (7 mg/min) developed transient obtundation. The remaining three patients, who received low-dose papaverine (1 mg/min), did not develop any neurologic symptoms. There was a trend for intracarotid papaverine to increase hemispheric CBF by 36% (33 ± 10 versus 45 ± 22 ml · 100 g−1 · min−1, P = .084, n = 6); papaverine decreased CVR from 1.3 ± 0.4 to 1.0 ± 0.3 mm Hg · ml−1 · 100 g−1 · min−1 (P = .049). There was no significant change in heart rate, MAP, or P ica during experimental protocol. Manipulation of CVR by intracarotid papaverine during acute hemispheric arterial hypotension appears to be feasible. Further studies are needed to establish safety and efficacy.
Prevention of spinal cord injury

To coincide with the International Day of Persons with Disabilities, 3 December, WHO has launched the International perspectives on spinal cord injury . This report summarises the best available evidence on the causes, prevention, care and lived experience of people with spinal cord injury (SCI) across the life course and throughout the world. The report follows on from the World report on disability and will further implement the Convention on the Rights of Persons with Disabilities (CRPD). The report has been developed in association with the International Spinal Cord Society and with support from Swiss Paraplegic Research. Globally, between 40 and 80 persons per million population suffer a traumatic spinal cord injury (TSCI) or non-traumatic spinal cord injury (NTSCI) every year. This means there are between 250 000 and 500 000 new cases annually: one to two new cases every minute. People with SCI are two to five times …
Validating the diagnosis of sensory processing disorders using EEG technology.

OBJECTIVE This study tested the assumption of sensory integration theory that states that a relationship exists between brain function and the behavioral manifestations of sensory integrative dysfunction. METHOD Electroencephalographic measures were used to examine brain processing in 28 children with sensory processing disorders (SPD) and 25 children who were typically developing, ages 5-12 years. RESULTS Children with SPD demonstrated less sensory gating than children who were typically developing. A significant relationship between sensory gating and age was found in children who were typically developing but not in children with SPD. Brain activity correctly distinguished children with SPD from children who were typically developing with 86% accuracy. CONCLUSION These results present empirical evidence that children with SPD display unique brain processing mechanisms compared to children who are typically developing and provide external validity for the diagnosis of SPD.
Post-failure recovery of MPI communication capability

As supercomputers are entering an era of massive parallelism where the frequency of faults is increasing, the MPI Standard remains distressingly vague on the consequence of failures on MPI communications. Advanced fault-tolerance techniques have the potential to prevent full-scale application restart and therefore lower the cost incurred for each failure, but they demand from MPI the capability to detect failures and resume communications afterward. In this paper, we present a set of extensions to MPI that allow communication capabilities to be restored, while maintaining the extreme level of performance to which MPI users have become accustomed. The motivation behind the design choices are weighted against alternatives, a task that requires simultaneously considering MPI from the viewpoint of both the user and the implementor. The usability of the interfaces for expressing advanced recovery techniques is then discussed, including the difficult issue of enabling separate software layers to coordinate their recovery.
On constructing parallel pseudorandom generators from one-way functions

We study pseudorandom generator (PRG) constructions G/sup f/ : {0, 1}/sup l/ /spl rarr/ {0, 1}/sup 1+s/ from one-way functions f : {0, 1}/sup n/ /spl rarr/ {0, 1}/sup m/. We consider PRG constructions of the form G/sup f/ (x) = C(f(q/sub 1/) . f (g/sub poly(n)/)) where C is a polynomial-size constant depth circuit (i.e., AC/sup 0/) and C and the q's are generated from x arbitrarily. We show that every black-box PRG construction of this form must have stretch s bounded as s /spl les/ 1 /spl middot/ (log/sup O(1)/ n)/m + O(1) = o(l). This holds even if the PRG construction starts from a one-to-one function f : {0,1}/sup n/ /spl rarr/ {0, 1}/sup m/ where m > 5n. This shows that either adaptive queries or sequential computation are necessary for black-box PRG constructions with constant factor stretch (i.e. s = /spl Omega/(l)) from one-way functions, even if the functions are one-to-one. On the positive side we show that if there is a one-way function f : {0, 1}/sup n/ /spl rarr/ {0, 1}/sup m/ that is regular (i.e. the number of preimages of f(x) depends on |x| but not on x) and computable by polynomial-size constant depth circuits then there is a PRG : {0, 1}/sup l/ /spl rarr/ {0, 1}/sup l + 1/ computable by polynomial-size constant depth circuits. This complements our negative result above because one-to-one functions are regular. We also study constructions of average-case hard functions starting from worst-case hard ones, i.e. hardness amplifications. We show that if there is an oracle procedure Ampf in the polynomial time hierarchy (PH) such that Ampf is average-case hard for every worst-case hard f, then there is an average-case hard function in PH unconditionally. Bogdanov and Trevisan (FOGS '03) and Viola (CCC'03) show related. but incomparable negative results.
Plasma cell-rich acute renal allograft rejection.

BACKGROUND Acute renal allograft rejection is usually seen within the first 3 months posttransplant, and is characterized by an intense infiltrate of T cells. Some acute rejections, however, contain many plasma cells and/or appear late posttransplant. METHODS We have investigated 27 cases of intensely plasma cell-rich acute rejections (PCAR) from 1987 to 1997 and have compared them to 21 control cases (CAR) of typical acute rejection. Each group was divided into early (<6 months) and late (>6 months) subgroups. PCAR and CAR cases were matched for histological features of chronic allograft nephropathy. In all four groups, most cases had Banff '97 type IB and IIA acute rejection. RESULTS A significantly greater number of PCAR cases experienced graft failure due to chronic allograft nephropathy or complications of acute rejection (P<0.05). There was no significant difference between PCAR and CAR in HLA matching, occurrence of posttransplant acute tubular necrosis, presence versus absence of previous allografts, number of previous or subsequent acute rejection episodes, Banff '97 sum scores for acute rejection, cyclosporine A or FK506 levels, or percent change from baseline creatinine at time of biopsy. Plasma cells in PCAR cases showed IgG predominance whereas those in CAR had comparable staining for IgG and IgA. Kappa and lambda light chain immunostaining of all PCAR cases revealed polyclonality. Three of 18 PCAR cases studied for the presence of Epstein-Barr virus RNA showed scattered positivity in 2-7% of lymphoid cells, although the remainder was negative. None of the PCAR cases developed post-transpland lymphoproliferative disorder. CONCLUSIONS We conclude that PCAR can occur from 1 month to many years posttransplant, is associated with poor graft survival, and is not a manifestation of concomitant chronic allograft nephropathy or viral infection, including posttransplant lymphoproliferative disorder.
Interactive Interpretation of Kohonen Maps Applied to Curves

For large customers, Electricite de France - the French national electric power company - stores every 10' the amount of electric power they consume. For each customer, these measures lead to curves called electric load curves. Clustering of electric load curves is a key problem for understanding the behavior of these customers. Several methods have been used but Kohonen maps give a very nice solution to this problem thanks to the visualization of the map. The work we present here describes a software for interactive construction and interpretation of a Kohonen map clustering, in the case of curves. The user can run the Kohonen map clustering, visualize the map, see external characteristics of curves linked to each cell of the map, find the cells figuring curves having some chosen external characteristics, define classes of cells, add comments on cells. User interaction is largely based on mouse clicking on the map cells and on bars of barcharts figuring external characteristics of the curves. This software is not dedicated to electric load curve analysis but can be used on any type of curve, for instance to analyze time series in finance.
The handbook of cognitive neuropsychology: What deficits reveal about the human mind

NeuropsychologyHandbook of Binding and Memory : Perspectives from Cognitive NeuroscienceHandbook of Cognitive NeuropsychologyThe Oxford Handbook of AttentionA Handbook of Neuropsychological AssessmentHandbook Of Clinical And Experimental NeuropsychologyThe Wiley Handbook on the Cognitive Neuroscience of LearningHandbook of Functional Neuroimaging of CognitionHandbook of Cognitive, Social, and Neuropsychological Aspects of Learning DisabilitiesHandbook of Medical NeuropsychologyThe Handbook of the Neuropsychology of Language, 2 Volume SetInternational Handbook of Cross-Cultural NeuropsychologyNeurocognitive Development: Normative DevelopmentHandbook on the Neuropsychology of Traumatic Brain InjuryHandbook of Pediatric NeuropsychologyThe Handbook of Clinical NeuropsychologyHandbook of Cognitive ScienceHandbook of Cognitive NeuroscienceThe Handbook of Adult Language DisordersThe Student's Guide to Cognitive NeuroscienceThe Oxford Handbook of Functional Brain Imaging in Neuropsychology and Cognitive NeurosciencesHandbook of CognitionThe Oxford Handbook of Adult Cognitive DisordersHandbook of Cognition and EmotionHandbook of Cognitive NeuropsychologyCognitive psychologyHandbook of Developmental Cognitive NeuroscienceHandbook of Cognitive AgingThe Oxford Handbook of Cognitive Neuroscience, Volume 1The Oxford Handbook of PsycholinguisticsThe Oxford Handbook of Cognitive PsychologyHandbook on the Neuropsychology of Aging and DementiaThe Oxford Handbook of Social NeuroscienceThe Wiley Handbook on The Cognitive Neuroscience of MemoryHandbook of the Neuroscience of AgingNeuropsychological RehabilitationThe Oxford Handbook of Numerical CognitionHandbook of School NeuropsychologyThe Oxford Handbook of 4E CognitionThe Wiley Handbook of Cognitive Control
Effects of androgenic-anabolic steroids on apolipoproteins and lipoprotein (a)

Objectives: To investigate the effects of two different regimens of androgenic-anabolic steroid (AAS) administration on serum lipid and lipoproteins, and recovery of these variables after drug cessation, as indicators of the risk for cardiovascular disease in healthy male strength athletes. Methods: In a non-blinded study (study 1) serum lipoproteins and lipids were assessed in 19 subjects who self administered AASs for eight or 14 weeks, and in 16 non-using volunteers. In a randomised double blind, placebo controlled design, the effects of intramuscular administration of nandrolone decanoate (200 mg/week) for eight weeks on the same variables in 16 bodybuilders were studied (study 2). Fasting serum concentrations of total cholesterol, triglycerides, HDL-cholesterol (HDL-C), HDL2-cholesterol (HDL2-C), HDL3-cholesterol (HDL3-C), apolipoprotein A1 (Apo-A1), apolipoprotein B (Apo-B), and lipoprotein (a) (Lp(a)) were determined. Results: In study 1 AAS administration led to decreases in serum concentrations of HDL-C (from 1.08 (0.30) to 0.43 (0.22) mmol/l), HDL2-C (from 0.21 (0.18) to 0.05 (0.03) mmol/l), HDL3-C (from 0.87 (0.24) to 0.40 (0.20) mmol/l, and Apo-A1 (from 1.41 (0.27) to 0.71 (0.34) g/l), whereas Apo-B increased from 0.96 (0.13) to 1.32 (0.28) g/l. Serum Lp(a) declined from 189 (315) to 32 (63) U/l. Total cholesterol and triglycerides did not change significantly. Alterations after eight and 14 weeks of AAS administration were comparable. No changes occurred in the controls. Six weeks after AAS cessation, serum HDL-C, HDL2-C, Apo-A1, Apo-B, and Lp(a) had still not returned to baseline concentrations. Administration of AAS for 14 weeks was associated with slower recovery to pretreatment concentrations than administration for eight weeks. In study 2, nandrolone decanoate did not influence serum triglycerides, total cholesterol, HDL-C, HDL2-C, HDL3-C, Apo-A1, and Apo-B concentrations after four and eight weeks of intervention, nor six weeks after withdrawal. However, Lp(a) concentrations decreased significantly from 103 (68) to 65 (44) U/l in the nandrolone decanoate group, and in the placebo group a smaller reduction from 245 (245) to 201 (194) U/l was observed. Six weeks after the intervention period, Lp(a) concentrations had returned to baseline values in both groups. Conclusions: Self administration of several AASs simultaneously for eight or 14 weeks produces comparable profound unfavourable effects on lipids and lipoproteins, leading to an increased atherogenic lipid profile, despite a beneficial effect on Lp(a) concentration. The changes persist after AAS withdrawal, and normalisation depends on the duration of the drug abuse. Eight weeks of administration of nandrolone decanoate does not affect lipid and lipoprotein concentrations, although it may selectively reduce Lp(a) concentrations. The effect of this on atherogenesis remains to be established.
Color image with Dim regions Enhancement Using Modified Histogram Equalization Algorithm

In this paper the color images with dim regions have been enhanced by using modified histogram equalization (MHE) algorithm. This technique uses the lightness component in YIQ color space is transformed using sigmoid function, then the traditional histogram equalization (HE) method is applied on Y component. A relationship between the mean and the average of standard deviation for images have been done for images with dim regions and select regions in these images, as well the histogram to examine the efficiency of the work. The result of MHE method has been compared with the result of other method like Adaptive Integrated Neighborhood Dependent Approach for Nonlinear Enhancement of Color Images (AINDANE) and traditional histogram equalization algorithm. All algorithms has implemented using program (Matlab). The suggestion algorithm appeared good enhancement for both regions with moderate and low lightness (dim region) compared with others algorithms.
Impact of ERP Implementation on Supply Chain Management

— This paper documents the effect of implementation of an ERP system within a firm and its impact on supply chain system . Supply chain design is becoming a core competency, and the enterprise resource planning (ERP) system is expected to be an integral component of supply chain management (SCM). Although an Enterprise Resource Planning (ERP) software provides different tools that can support supply chain integration but at the same time it has several features that obstruct the integration with various business functions. Installing an ERP system is, however, expensive and risky. IT managers must decide how to use their limited resources and invest in the right product. Another important aspect that has been highlighted is impact of forecasting in supply chain. Although the effect seems to be broad but has its own shortcomings.