Miracle-dz/UniFAR-FTUs huggingface dataset:
Gene Selection Using Gene Expression Data in a Virtual Environment

1 Gene Selection for Drug Discovery The gene expression data of many normal and diseased tissues enables the selection of genes that satisfy the conditions for finding a new drug. In the process of selecting genes is required to determine many filtering parameters. The system of the selection of genes from all genes is required to have the following features: 1) visualization of the data to provide the users to grasp both holistic and detail views of the data, 2) interactivity to determine many filtering parameters, 3) provides spatial cue to understand intuitively because there are many filtering parameters. In order to visualize various information of large number of genes, the system also needs a wide field of view. Virtual reality technology satisfies these requirements above.
Analysis of Fitness Function in Designing Genetic Algorithm Based Intrusion Detection System

Network Intrusion detection system is tool to monitor & identify intrusion in computers networks. The genetic algorithm is employed to derive a set of classification rules from network audit data. Different data sets are used as an audit data . From these data sets only specific features are selected and represented as chromosomes, which represent rules. The weighted sum model, support-confidence framework or reward penalty framework is utilized as fitness function to judge the quality of each rule. Best rule collection or knowledge base improves IDS performance by improving detection rate and reducing false alarm rate. The weighted sum model is generally more helpful for identification of network anomalous behaviors. The support –confidence framework is simply identifying network intrusions or precisely classifying the types of intrusions. Reward penalty technique used to give reward to the good chromosome and to apply penalty on the bad chromosome. This paper gives detail study about research carried out in fitness function of genetic based intrusion detection system.
Design and Analysis of a Novel Miniature Tubular Linear Actuator

This paper investigates a novel miniature-size resonant moving-magnet linear actuator designs to be used in miniature linear compressor applications. The miniature linear actuator has a slotless stator and a tubular topology. It utilizes moving magnets in which the magnets are lined up in the Halbach array structure. Finite-element and analytical analyses of the actuator are performed to determine the flux density and thrust force. Experimental thrust force behavior at the resonant frequency is determined. It is shown that the finite-element method simulation, analytical, and experimental results agree with each other.
Post-traumatic Reactions and Their Predictors among Workers Who Experienced Serious Violent Acts: Are There Sex Differences?

Background Serious violent acts (e.g. physical violence, robbery, sexual aggression and death threats) are among the most visible and notable examples of workplace violence. Although women are commonly found to be at higher risk for post-traumatic reactions following workplace violence, little is known as regards sex differences concerning the types of post-traumatic reactions and their predictors. Objective This study aimed to describe sex differences in the post-traumatic reactions of serious violent acts and the predictors of such reactions. Methods The study was conducted among a convenience sample of 2889 French-speaking workers from Quebec, Canada by using a self-administrated survey. Linear regression modelings and post-hoc comparisons of coefficients according to the sex of the respondents were used to achieve the objective. Results Preliminary results confirmed that while men are more exposed to violence at work, women experience a greater number of post-traumatic reactions. Women were more affected by flashbacks, avoidance, and hypervigilance than men. The results also showed that being victimized by a male aggressor was associated with a greater number of post-traumatic reactions for women, whereas being victimized by an insider (e.g. colleague, supervisor, employee) was associated with a greater number of post-traumatic reactions for both sexes. Implications These findings highlight the necessity to better consider sex as a potential determinant of mental health in studies on workplace violence.
Neurodevelopmental outcome at early school age of children born to mothers with gestational diabetes

AIMS To study the metabolic derangements in the second half of pregnancy caused by gestational diabetes, on the long term development of children. METHODS The neuropsychological function of 32 school age children born to 32 mothers with well controlled gestational diabetes and 57 control children matched by age, birth order, and parental socioeconomic status was studied. RESULTS There were no differences in head circumference and height, but the children born to diabetic mothers were heavier. The verbal IQ scores of index children below the age of 9 years were lower than those of control children. No differences were found between the groups in various sensory and motor functions and in the Touwen and Prechtl neurological test. The young index group children performed less well than controls in fine and gross motor functions, as observed on the Bruininks–Oseretzky test of motor proficiency. The scores of young children born to mothers with gestational diabetes were also lower than controls on the Pollack tapper test, and there were more index group children who scored abnormally on the parents’ Conners questionnaire.No correlation was found between the performance of the index group children on various neurodevelopmental tests and the severity of perinatal complications. The differences tended to disappear with age. CONCLUSIONS Gestational diabetes, as a result of the metabolic abnormalities in the second half of pregnancy, induces long term minor neurological deficits which are more pronounced in younger children. There does not seem to be any direct relation between the appearance of congenital anomalies and neurodevelopmental outcome.
Effects of Two Different Dosages of Sildenafil on Patients With Erectile Dysfunction

To investigate the effects of two different dosages of sildenafil on patients with erectile dysfunction (ED), a total of 3,674 patients with ED were recruited to answer questionnaires designed specifically for this study. There were 977 patients in the 50 mg group and there were 2,697 patients in the 100 mg group. Both 50 mg and 100 mg of sildenafil therapy increased the ED patients’ average monthly frequency of sexual intercourse, improved erectile function state in self-assessment, and elevated sexual satisfaction and enjoyment. Despite a higher rate of concomitant diseases, patients in the higher dosage of sildenafil group had a better outcome in the average monthly frequency of sexual intercourse and sexual enjoyment compared with those in the lower dosage. Such a study might be helpful for health care providers to choose sildenafil dosage for patients with ED.
An evaluation of (Z)‐9‐tricosene and food odours for attracting house flies, Musca domestica, to baited targets in deep‐pit poultry units

Field trials investigating the effect of food baits on catches of Musca domestica at toxic targets impregnated with the female sex pheromone, (Z)‐9‐tricosene, were conducted in a caged‐layer deep‐pit poultry unit in southern England. Targets treated with an Alfacron‐sugar mixture and baited with 2.5 g of 40% (Z)‐9‐tricosene beads caught significantly greater numbers of both male and female M. domestica than control targets. Egg and milk‐baited targets were less attractive than controls, while brewers yeast slightly increased the numbers of M. domestica attracted. However, the inclusion of brewers yeast in (Z)‐9‐tricosene‐impregnated targets produced a significant reduction in the number of male M. domestica attracted. Increased female attraction was elicited by baiting the targets with 2‐phenylethanol, at the quantities of 1 mg and 10 mg. However, 2‐phenylethanol had no effect on female attraction when presented in conjunction with (Z)‐9‐tricosene. The implications of these results in relation to the control of M. domestica populations in poultry units are discussed.
Universität Des Saarlandes Fachrichtung 6.1 – Mathematik Perspective Shape from Shading for Phong-type Non-lambertian Surfaces Perspective Shape from Shading for Phong-type Non-lambertian Surfaces

The shape-from-shading (SfS) problem in computer vision is to compute at hand of the shading variation in a given 2-D image the 3-D structure of depicted objects. We introduce an efficient numerical method for a new perspective SfS model for general non-Lambertian surfaces. First, the modelling process is given in detail. The model is based on the perspective model for Lambertian surfaces recently studied by Prados et al., which we extend by use of the Phong reflection model incorporating ambient, diffuse and specular components. The arising partial differential equation (PDE) is a non-linear time-independent Hamilton-Jacobi equation. In order to compute the sought viscosity supersolution of the PDE, we introduce an artificial time into the equation and solve for the steady state. Based on a multi-scale analysis of the PDE, we construct a fully explicit numerical method and elaborate on its stability. In order to achieve fast convergence of the resulting iterative scheme, a coarse-to-fine strategy combined with a sweeping technique is employed. Numerical experiments show the benefits of our approach: While computational times stay reasonable even for quite large images, a substantial qualitative gain can be achieved by use of the new model. Moreover, the computational technique is relatively easy to implement compared to other approaches in the field.
MIMO Wiretap Channels Based on Generalized Extended Orthogonal STBCs and Feedback

This paper presents a two-phase process consisting of advantage distillation (AD) and information reconciliation for achieving secret sharing over a wiretap channel. By using the feedback bits from the legitimate receiver to transmitter, we propose a novel AD scheme for multiple-input multiple-output (MIMO) wiretap (MIMO-WT) channels. We first generalize the extended orthogonal space-time block codes (EO-STBCs). Then, based on the generalized EO-STBCs (GEO-STBCs) and channel state information (CSI), the feedback bits transmitted from the legitimate receiver to the transmitter are generated to increase the signal-to-noise ratio (SNR) gap between the legitimate receiver and the eavesdropper. Simulation results show that the feedback performance gain of the proposed AD scheme increases rapidly with the number of transmit antennas and the value of SNR. A bit error rate (BER) performance gain up to 5.5 dB is obtained by the legitimate receiver over the eavesdropper at the BER of $10^{-5}$. Moreover, it is also shown that the secrecy capacity of two-way MIMO-WT channels with feedback grows rapidly in low SNR regime and grows slowly in high SNR regime.
Subjective and Objective Sound-Quality Evaluation of Adaptive Feedback Cancellation Algorithms

Objective measures are widely used for the perceptual sound-quality evaluation of audio signal processing algorithms. Nevertheless, the use of subjective-evaluation measures remains relevant, in particular when application-specific objective measures are lacking. In this paper, we present a perceptual sound-quality evaluation of different algorithms for adaptive feedback cancellation (AFC), with both speech and music signals. Three algorithms are compared: the block normalized least mean squares algorithm, the prediction-error method (PEM) based frequency-domain adaptive filter, and the PEM-based frequency-domain Kalman filter (PEM-FDKF). The subjective evaluation results for the tested algorithms suggest that there is a large difference in statistical significance, and a corresponding large effect size, between the PEM-FDKF and the other algorithms, when using speech signals. A smaller statistical significance, and a lower effect size, is reported when using music signals. The subjective evaluation results are then compared with the results obtained with several objective measures. The correlation between subjective and objective scores shows that objective measures can be effectively used to predict the sound-quality degradation caused by acoustic feedback and AFC artifacts.
Molecular characterization of Trypanosoma evansi isolates from water buffaloes (Bubalus bubalis) in the Philippines

Trypanosoma evansi infection in the Philippines is frequently reported to affect the country’s livestock, particularly, the buffaloes. To assess the prevalence and intraspecific diversity of T. evansi in the country, blood samples from water buffaloes in different geographical regions were collected during an outbreak. T. evansi was detected in all 79 animals tested using PCR targeting the RoTat 1.2 VSG gene. Sequencing of the rDNA complete internal transcribed spacer (ITS) region including the 5.8S subunit showed high similarity (99–100%) between Philippine isolates and known T. evansi isolates in Genbank. Tree construction based on the same region confirmed the close relationship between Philippine and reported Thai isolates as compared to Egyptian isolates separated by relatively small genetic distances, 47 polymorphisms, despite the clustering in four branches. Overall, the results of this study prove genetic diversity within T. evansi species despite previous reports on limited heterogeneity among isolates worldwide.
Comparison of thetime interval betweentheonset ofclinical symptoms and receiving streptokinase inpatients withacutemyocardial infarction (ami) at amir hospital in zabol, iran, 2013

Myocardial infarction (MI) or acute myocardial infarction(AMI) is known as heart attack. MI occurs when blood stops flowing properly to a part of the heart. MI occurred when one of the coronary arteries develops a blockage due to an unstable buildup of with blood, cholesterol and fat. This study aimed to determine the time interval between theonset ofclinical symptoms and receiving streptokinase inpatients withacutemyocardial infarction (AMI) at Amir Hospital in Zabol city in 2013. This was a cross-sectional-descriptive study. In total 72 patients were selected from all patients with chest pain and who referred to the emergency of Amir Hospital during 2013 in Zabol located in southeast of Iran. All patients were diagnosed with AMI. The instrument usedfordata collectionwas a questionnaire includingdemographic characteristics, record of exact location of infarction,ECG, the time of patients’ arrival to the emergency department (ED), and the time of receiving streptokinase.According to the obtained results of this study, the mean ofonset to call, call to door, anddoor to needletimes were 269.29±197.33, 34.02±12.32, and 96.33±49.95, respectively. The comparison ofonset to call, andcall to door and age, education and place of residence variables showed that there was a significant differencebetweenthese variables. In addition, the comparison ofdoor to needletime and age, sex, education and place of residence variables showed that there was no significant differencebetweenthese variables.Delay intreatmentof patients with STEMIiscaused as a result ofseveral factorsincluding rate of patient’sawarenessandemergency status. We need to provide opportunities to treatment ofMI by emergency and outpatientcenters. To reducing in-hospital delay, we must teach physiciansandemergency personnelto rapid diagnosis ofMI.
Coming or going? Un-BLOC-ing delivery and recycling pathways during melanosome maturation

Melanosome biogenesis requires successive waves of cargo delivery from endosomes to immature melanosomes, coupled with recycling of the trafficking machinery. Dennis et al. (2016. J. Cell Biol. http://dx.doi.org/10.1083/jcb.201605090) report differential roles for BLOC-1 and BLOC-3 complexes in delivery and recycling of melanosomal biogenetic components, supplying directionality to melanosome maturation.
Modelling of 7050 aluminium alloy friction stir welding

A thermal model combined with a microstructural and yield strength model has been developed to give a prediction of precipitate evolution and strength in the as welded and post-weld heat treated condition for friction stir welding of 7xxx aerospace aluminium alloys. This fully coupled model is applied to an overaged high strength 7050 aluminium alloy friction stir welded using a range of welding rotation and translation speeds. The evolution of the microstructure has been predicted as a function of the process parameters. The resulting microstructural evolution is shown to be a complex function of both peak temperature observed during the weld cycle and heating/cooling rates. Yield strength has been calculated from the microstructural predictions and a comparison between predicted yield strength and measured hardness has been used to test the modelling approach. Reasonably good agreement between model and experiment is found over the wide range of process parameters investigated.
Community Mitigation Guidelines to Prevent Pandemic Influenza — United States, 2017

Summary When a novel influenza A virus with pandemic potential emerges, nonpharmaceutical interventions (NPIs) often are the most readily available interventions to help slow transmission of the virus in communities, which is especially important before a pandemic vaccine becomes widely available. NPIs, also known as community mitigation measures, are actions that persons and communities can take to help slow the spread of respiratory virus infections, including seasonal and pandemic influenza viruses. These guidelines replace the 2007 Interim Pre-pandemic Planning Guidance: Community Strategy for Pandemic Influenza Mitigation in the United States — Early, Targeted, Layered Use of Nonpharmaceutical Interventions (https://stacks.cdc.gov/view/cdc/11425). Several elements remain unchanged from the 2007 guidance, which described recommended NPIs and the supporting rationale and key concepts for the use of these interventions during influenza pandemics. NPIs can be phased in, or layered, on the basis of pandemic severity and local transmission patterns over time. Categories of NPIs include personal protective measures for everyday use (e.g., voluntary home isolation of ill persons, respiratory etiquette, and hand hygiene); personal protective measures reserved for influenza pandemics (e.g., voluntary home quarantine of exposed household members and use of face masks in community settings when ill); community measures aimed at increasing social distancing (e.g., school closures and dismissals, social distancing in workplaces, and postponing or cancelling mass gatherings); and environmental measures (e.g., routine cleaning of frequently touched surfaces). Several new elements have been incorporated into the 2017 guidelines. First, to support updated recommendations on the use of NPIs, the latest scientific evidence available since the influenza A (H1N1)pdm09 pandemic has been added. Second, a summary of lessons learned from the 2009 H1N1 pandemic response is presented to underscore the importance of broad and flexible prepandemic planning. Third, a new section on community engagement has been included to highlight that the timely and effective use of NPIs depends on community acceptance and active participation. Fourth, to provide new or updated pandemic assessment and planning tools, the novel influenza virus pandemic intervals tool, the Influenza Risk Assessment Tool, the Pandemic Severity Assessment Framework, and a set of prepandemic planning scenarios are described. Finally, to facilitate implementation of the updated guidelines and to assist states and localities with prepandemic planning and decision-making, this report links to six supplemental prepandemic NPI planning guides for different community settings that are available online (https://www.cdc.gov/nonpharmaceutical-interventions).
Identifying Biologically Meaningful Hot-Weather Events Using Threshold Temperatures That Affect Life-History

Increases in the frequency, duration and intensity of heat waves are frequently evoked in climate change predictions. However, there is no universal definition of a heat wave. Recent, intense hot weather events have caused mass mortalities of birds, bats and even humans, making the definition and prediction of heat wave events that have the potential to impact populations of different species an urgent priority. One possible technique for defining biologically meaningful heat waves is to use threshold temperatures (Tthresh) above which known fitness costs are incurred by species of interest. We set out to test the utility of this technique using Tthresh values that, when exceeded, affect aspects of the fitness of two focal southern African bird species: the southern pied babbler Turdiodes bicolor (Tthresh = 35.5°C) and the common fiscal Lanius collaris (Tthresh = 33°C). We used these Tthresh values to analyse trends in the frequency, duration and intensity of heat waves of magnitude relevant to the focal species, as well as the annual number of hot days (maximum air temperature > Tthresh), in north-western South Africa between 1961 and 2010. Using this technique, we were able to show that, while all heat wave indices increased during the study period, most rapid increases for both species were in the annual number of hot days and in the maximum intensity (and therefore intensity variance) of biologically meaningful heat waves. Importantly, we also showed that warming trends were not uniform across the study area and that geographical patterns in warming allowed both areas of high risk and potential climate refugia to be identified. We discuss the implications of the trends we found for our focal species, and the utility of the Tthresh technique as a conservation tool.
Brooding rumination and attentional biases in currently non-depressed individuals: an eye-tracking study

ABSTRACT Both rumination and attentional biases have been proposed as key components of the RDoC Negative Valence Systems construct of Loss. Although theorists have proposed that rumination, particularly brooding rumination, should be associated with increased sustained attention to depression-relevant information, it is not clear whether this link would be observed in a non-depressed sample or whether it is specific to brooding versus reflective rumination. To address these questions, the current study examined the link between brooding rumination and attentional biases in a sample of non-depressed individuals (n = 105). Attentional biases were assessed using eye tracking during a passive viewing task in which participants were presented with 2 × 2 arrays of angry, happy, sad, and neutral faces. In line with predictions, higher levels of brooding rumination were associated with greater sustained attention to sad faces and less sustained attention to happy faces. These results remained significant after controlling for participants’ prior history of major depression and current nonclinical level of depressive symptoms, suggesting that the link between brooding rumination and attentional biases is at least partially independent of current or past depression.