Miracle-dz/UniFAR-FTUs huggingface dataset:
Singular p-adic transformations for Bernoulli product measures

Ergodic properties of p-adic transformations have been studied with respect to Haar measure. This paper extends the study of these properties to measures beyond Haar measure. Under these measures, coefficients do not appear in equal proportions. Adding a rational number that is not an integer then takes likely strings of coefficients to one of two unlikely strings of coefficients. It follows from this inequality that translation by a rational number other than an integer is singular with respect to these measures. Conjugation gives similar results for multiplication by rational numbers.
PupaSuite: finding functional single nucleotide polymorphisms for large-scale genotyping purposes

We have developed a web tool, PupaSuite, for the selection of single nucleotide polymorphisms (SNPs) with potential phenotypic effect, specifically oriented to help in the design of large-scale genotyping projects. PupaSuite uses a collection of data on SNPs from heterogeneous sources and a large number of pre-calculated predictions to offer a flexible and intuitive interface for selecting an optimal set of SNPs. It improves the functionality of PupaSNP and PupasView programs and implements new facilities such as the analysis of user's data to derive haplotypes with functional information. A new estimator of putative effect of polymorphisms has been included that uses evolutionary information. Also SNPeffect database predictions have been included. The PupaSuite web interface is accessible through and through .
Developing an interdisciplinary innovative Master of Gerontology program.

PURPOSE This study describes the goals, development, and outcomes of an innovative, interdisciplinary, Master of Gerontology department, one of two programs in Israel developed to answer Israel's needs for highly educated researchers and practitioners. DESIGN Key program components reflecting the program's innovative nature are described: (a) level of development and promotion of knowledge; (b) goals; (c) influence; and (d) patronage. RESULTS An interdisciplinary faculty and student body both report a high satisfaction level, involvement, and the obtainment of wide knowledge bases in gerontology and geriatrics. The number of candidates for the program increases each year. A new unique program for physicians has evolved, with strong support from the University of Haifa, the Council for Higher Education in Israel, and key service organizations for the elderly population. IMPLICATIONS Such a program enhances the level of professional leadership in the field of aging, and it expands the cadre of academic faculty.
ACL Fixation Devices

Secure graft fixation for anterior cruciate ligament reconstruction is an important goal. Optimally, graft fixation allows for an aggressive postoperative rehabilitation program with the goals of immediate full range of motion, full weight bearing, and an early return to athletic activity. Current anterior cruciate ligament reconstruction techniques advance soft tissue grafts with or without bone plugs into the joint to replace the damaged ligament. Segments of these grafts are fixed within a bone tunnel or on the periosteum at a distance from the normal ligament attachment site. The graft fixation should be secure, allow normal tendon healing, and provide the graft construct with biomechanical properties, which approach that of the native ligament. Several different fixation devices are available for anterior cruciate ligament construction.
The role of word-word co-occurrence in word learning

A growing body of research on early word learning suggests that learners gather word-object co-occurrence statistics across learning situations. Here we test a new mechanism whereby learners are also sensitive to word-word co-occurrence statistics. Indeed, we find that participants can infer the likely referent of a novel word based on its co-occurrence with other words, in a way that mimics a machine learning algorithm dubbed ‘zero-shot learning’. We suggest that the interaction between referential and distributional regularities can bring robustness to the process of word acquisition.
On the parallel decomposability of geometric problems

There is a large and growing body of literature concerning the solution of geometric problems on mesh-connected arrays of processors [5,9,14,17]. Most of these algorithms are optimal (i.e., run in time <italic>&Ogr;</italic>(<italic>n</italic><supscrpt>1/d</supscrpt>) on a <italic>d</italic>-dimensional <italic>n</italic>-processor array), and they all assume that the parallel machine is trying to solve a problem of size <italic>n</italic> on an <italic>n</italic>-processor array. What happens when we have parallel machine for efficiently solving a problem of size <italic>p</italic>, and we are interested in using it to solve a problem of size <italic>n</italic> < <italic>p</italic>? The answer to that question has to do with a fundamental, and yet (at least so far) little-studied property of geometric problems: their <italic>parallel-decomposability</italic>. More specifically, given that a problem of size <italic>p</italic> can be solved on a parallel machine P faster by a factor of (say) <italic>s</italic>(<italic>p</italic>) than on a RAM alone, then that problem is <italic>fully parallel-decomposable for</italic> P if a RAM to which the parallel machine P is attached can solve arbitrarily large problems with a speedup of also <italic>s</italic>(<italic>p</italic>) when compared to a RAM alone. The issue has been settled for the sorting problem when P is a linear systolic array [1,2,3,11]. Here we show that many geometric problems are fully parallel-decomposable for (multidimensional) mesh-connected arrays of processors.
Analgesic efficacy of three different dosages of intra-articular morphine in arthroscopic knee surgeries: Randomised double-blind trial

Background and Aims: Arthroscopic knee surgery is a common procedure and may cause enough pain to delay rehabilitation. Intra-articular (IA) morphine is a known modality for post-operative pain relief. However, the optimal dose of IA morphine has not been studied. The current study has been conducted to find out the optimal dosage of IA morphine when administered with 0.25% bupivacaine. Methods: Sixty adult patients of either sex, aged between 18 and 60 years, undergoing diagnostic/therapeutic knee arthroscopic surgery were included in the study and randomised into three groups. All patients underwent surgery under subarachnoid block. After the surgical closure, 20 ml of 0.25% bupivacaine with 1 mg, 3 mg and 5 mg of morphine as additive was injected intra-articularly in Group A, B and C patients, respectively. Post-operative pain assessment was performed with visual analogue scale score in the 1st, 2nd, 6th, 12th and 24th post-operative hour. The common complications were also recorded. Results: There was statistically significant analgesia in Group B and C than Group A in the 1st and 2nd post-operative hour; while at the 24th post-operative hour, Group C had statistically significant analgesia than the other two groups. Time to first rescue analgesia was statistically significantly less and consumption of supplemental analgesia was significantly higher in Group A than the other two groups. Conclusion: IA dose of 3 mg and 5 mg morphine with 20 ml of 0.25% bupivacaine provided adequate analgesia. However, 3 mg morphine group patients had fewer side effects than 5 mg group patients although the difference was not statistically significant.
Wealth Inequality and Mental Disability Among the Chinese Population: A Population Based Study

In the study described herein, we investigated and explored the association between wealth inequality and the risk of mental disability in the Chinese population. We used nationally represented, population-based data from the second China National Sample Survey on Disability, conducted in 2006. A total of 1,724,398 study subjects between the ages of 15 and 64, including 10,095 subjects with mental disability only, were used for the analysis. Wealth status was estimated by a wealth index that was derived from a principal component analysis of 10 household assets and four other variables related to wealth. Logistic regression analysis was used to estimate the odds ratio (OR) and 95% confidence interval (CI) for mental disability for each category, with the lowest quintile category as the referent. Confounding variables under consideration were age, gender, residence area, marital status, ethnicity, education, current employment status, household size, house type, homeownership and living arrangement. The distribution of various types and severities of mental disability differed significantly by wealth index category in the present population. Wealth index category had a positive association with mild mental disability (p for trend <0.01), but had a negative association with extremely severe mental disability (p for trend <0.01). Moreover, wealth index category had a significant, inverse association with mental disability when all severities of mental disability were taken into consideration. This study’s results suggest that wealth is a significant factor in the distribution of mental disability and it might have different influences on various types and severities of mental disability.
Portuguese working group advocacy for intergenerational policies: challenges and results

Purpose – The purpose of this paper is to present the benefits and challenges of the advocacy group for intergenerational policies that was created in Portugal in 2012, the European Year of Active Ageing and solidarity between generations. Design/methodology/approach – The group conducted nine closed group meetings scheduled every three months with an average attendance of five members and six public events bringing together researchers, policy makers, practitioners and civil society. Findings – The group was established as a response to the various social changes happening in Portugal as a consequence of the ageing population, low-birth rate and migration, leading to the need to explore new responses which are based both on the need to promote active ageing and intergenerational solidarity and also the importance of family and state support to multigenerational families as a building block to strengthen communities. Research limitations/implications – The paper sets the context of the changing social sit.
Clique Partitions of Dense Graphs October 2 , 2006

In this paper, we prove that for any forest F ⊂ Kn, the edges of E(Kn)\E(F ) can be partitioned into O(n log n) cliques. This extends earlier results on clique partitions of the complement of a perfect matching and of a hamiltonian path in Kn. We also show that if a graph G has maximum degree 4, then the edges of E(Kn)\E(G) can be partitioned into roughly n 3 24 1 2 log n cliques provided there exist Steiner systems with certain parameters. Furthermore, as n → ∞, almost every 4-regular graph G on n vertices has the property that E(Kn)\E(G) cannot be partitioned into fewer than about 42[ log n log4 − 1] cliques.
Subjective contours, amodal completion, and transparency in animals

Perception of 'subjective contours', 'amodal completion', and 'transparency' is one of the controversial problems in human perception studies of the day. This paper attempts to outline the studies focused on perception of these phenomena in a variety of animals. Dozens of results have indicated that animals are capable of perceiving some of these phenomena except pigeons in amodal completion. It is also reported that perception of tested animals is comparable to that of humans'. Moreover, we reviewed some neurophysiological studies that examined some brain areas related to the perception. Our review of the studies suggest that the process for these perceptual phenomena is common among animals, including humans, and that process is involved in figure-ground segregation and surface perception. However, clarification of the process awaits further studies that directly compare humans and animals.
Intelligent Robotic Mapping and Exploration with Converging Target Localization

This paper presents different methodologies for a maze solving agent in unknown environments. The developed methodologies include an odometry based localization system, a converging target localization based on the centre of mass of recursive triangulations, and a regressive obstacle distance function, along with an obstacle setting and sweeping mechanism for mapping. A quad-tree solution was used for map representation, and an innovative exploring A* for path planning was developed. A quasi-reactive, wall-following agent serves as a comparison basis and a simulation environment called ciber-rato was used to test the implemented architecture and validate the developed methods within gradually increasing difficult scenarios. Besides the reactive agent being typically less time consumptive, the exploring architecture granted greater consistency and robustness. The results also evinced the time-improvement of using the exploring A* and the efficiency of this target localization method as gradually converging to the real target position.
Pharmacokinetics of Carbamazepine in Man: A Review

Gas-liquid chromatographic methods for determining plasma concentrations of the anticonvulsant drug carbamazepine are described. The pharmacokinetics of carbamazepine (absorption, protein binding, distribution, metabolism, and elimination) are reviewed, as well as the relationship between dose and plasma level and between plasma level and drug effects. Interactions with other drugs are noted.
Evaluation of the Control of West Nile Virus in Ontario: Did Risk Patterns Change from 2005 to 2012?

The goal of this study was to evaluate and compare the risk distribution of human cases of West Nile virus (WNV) disease in Ontario in 2005 to 2012. The objectives were to: map the risk distribution of WNV in 2005 and 2012, identify clusters of human WNV disease and determine whether the clusters are significantly different between the years 2005 and 2012. West Nile virus surveillance data were used to calculate empirical Bayesian smoothed estimates of disease incidence in southern Ontario for 2005 and 2012. Choropleth maps were generated to visualize the spatial risk distribution, and the spatial scan test was performed to identify clusters of disease. Following identification of clusters for 2005 and 2012, a Poisson model was applied to the 2012 human WNV incidence adjusted for the smoothed human WNV incidence rate from 2005 and the scan test was repeated. Two significant clusters were identified in both the year 2005 and 2012. In 2005, the primary cluster was located in the Windsor‐Essex and Chatham‐Kent public health units (PHUs). For 2012, the primary cluster was identified in the Golden Horseshoe area. A cluster analysis for 2012 adjusted for those identified in 2005 resulted in one significant cluster in the Windsor‐Essex PHU. In 2012, the Windsor‐Essex PHU remained as a high‐risk area for human WNV disease when compared with the rest of southern Ontario. Although overall risk may change from year to year, public health programming should be employed to decrease the relative risk of WNV in this area.
Acetazolamide responsiveness in familial hemiplegic migraine

1. Gilman S, Sima AAF, Junck L, et al. Spinocerebellar ataxia type 1 with multiple system degeneration and glial cytoplasmic inclusions. Ann Neurol 1996;39:241-255 2. Genis D, Matilla T, Volpini V, et al. Clinical, neuropathologic and genetic studies of a large spinocerebellar ataxia rype 1 (SCA1) kindred: (CAG)n expansion and early premonitory signs and symproms. Neurology 1995;45:24-30 3. Ferrer I, Genis D, Divalos A, et al. The Purkinje cell in olivopontocerebellar atrophy. A Golgi and immunocytochemical study. Neuropathol Appl Neurobiol 1994;20:38-46 4. Berciano J. Olivoponrocerebellar atrophy. A review of 117 cases. J Neurol Sci 1982;53:253-272 5. Daniel SE, Geddes JF, Revesz T. Glial cytoplasmic inclusions are not exclusive to multiple system atrophy. J Neurol Neurosurg Psychiatry 1995;58:262 (Letter)
Axonal Transport of Gangliosides in the Goldfish Optic Nerve

Radioactive glucosamine and N-acetylmannosamine injected into the goldfish eye are incorporated into gangliosides that undergo rapid axonal transport to the optic nerve terminals. All ganglioside fractions are labeled. These data provide the first evidence that axonal transport has a role in neuronal ganglioside function and metabolism.
Clinical update on the therapeutic use of clopidogrel: treatment of acute ST-segment elevation myocardial infarction (STEMI)

The pathogenesis of ST-elevation myocardial infarction (STEMI) involves plaque disruption, platelet aggregation and intracoronary artery thrombus formation. Aspirin is the cornerstone of antiplatelet therapy in patients with STEMI, reducing the risk of recurrent myocardial infarction or death during the acute phase and long term by about one-quarter. Recent large randomized trials have demonstrated that the addition of clopidogrel to aspirin reduces the risk of major ischemic events by up to a further one-third in patients with STEMI treated with fibrinolytic therapy and undergoing percutaneous coronary intervention, with no significant increase in bleeding. Thus, dual antiplatelet therapy with the combination of clopidogrel and aspirin is becoming the new standard of care for the management of patients with STEMI.
Comparative Transcriptome Profiling of Maize Coleoptilar Nodes during Shoot-Borne Root Initiation1[C][W][OPEN]

A microarray analysis reveals 828 unique transcripts with expression related to crown root initiation during coleoptilar node development. Maize (Zea mays) develops an extensive shoot-borne root system to secure water and nutrient uptake and to provide anchorage in the soil. In this study, early coleoptilar node (first shoot node) development was subjected to a detailed morphological and histological analysis. Subsequently, microarray profiling via hybridization of oligonucleotide microarrays representing transcripts of 31,355 unique maize genes at three early stages of coleoptilar node development was performed. These pairwise comparisons of wild-type versus mutant rootless concerning crown and seminal roots (rtcs) coleoptilar nodes that do not initiate shoot-borne roots revealed 828 unique transcripts that displayed RTCS-dependent expression. A stage-specific functional analysis revealed overrepresentation of “cell wall,” “stress,” and “development”-related transcripts among the differentially expressed genes. Differential expression of a subset of 15 of 828 genes identified by these microarray experiments was independently confirmed by quantitative real-time-polymerase chain reaction. In silico promoter analyses revealed that 100 differentially expressed genes contained at least one LATERAL ORGAN BOUNDARIES domain (LBD) motif within 1 kb upstream of the ATG start codon. Electrophoretic mobility shift assay experiments demonstrated RTCS binding for four of these promoter sequences, supporting the notion that differentially accumulated genes containing LBD motifs are likely direct downstream targets of RTCS.
Testing, Contesting and Legitimizing Technology Diffusion in Regulated Environments

Based on a longitudinal case study approach, this paper shows that the legitimation processes of technology diffusion in regulated environments is subjected to distinct power struggles manifested in different framing contests when several competing technological frames are crafted, are contradictory and attempt at capturing the same resources. We show that technology framing contests increase ambiguity which may in turn spark the need to rely on technology testing in order to bring a resolution of the debate, to lower ambiguity and to provide legitimacy to the purpose and benefits of a technology. Furthermore, we show that when framing contests over diffusion cannot be resolved through legitimated means, institution testing may come into play. This is likely to occur when the cultural-cognitive legitimacy of a technology has acquired sufficient force to trump regulatory legitimacy.
Flow Control in Communication Networks with Competing Teams of Cooperative Users

In this paper, we investigate flow control schemes for general communication networks with competing teams of cooperative users. Previously, for general network topologies flow control mechanisms for networks with all competitive users and with all cooperative users have been studied. In this paper, we use a hierarchical flow control scheme which is capable to represent a more realistic network condition in which there are multiple competitive teams, each team having cooperative users. That is, each team competes with the others to provide the best possible performance for its members (users) and members of each team cooperate to increase their team's performance. All- competitive and all-cooperative cases are simply two special cases of this hierarchical model. That is, the network involves all cooperative users when there is only one team in the network and the network involves all competitive users when there are multiple teams but each having only one user. In this model, each user tries to maximize a power criterion utility function and each team tries to maximize a team's utility function which is a weighted sum of utilities of the users in this team. We use Pareto and Non-Inferior Nash strategies as solution concepts for one team and multiple team flow control problems respectively. We compare the results of these strategies to those corresponding to the standard Nash strategy and using an illustrative example we observe that users can possibly obtain larger utilities when they are in a team than when they operate competitively on their own.
Adaptive Cross-layer QoS for priority-based video streaming over wireless channel

Real-time streaming over wireless networks is a challenging proposition due to the highly variable nature of wireless links and the resource-poor nature of mobile device. In such a context, transmission control schemes have to dynamically adapt both to the application requirements and to the channel conditions. In this paper, we propose an adaptive cross-layer quality-of-service (QoS) scheme for wireless channel and streaming applications. For the sake of adaptive QoS, the Cross-layer architecture assumed that layers information could be exchanged between application layers and lower layers. In addition, priority-based adaptive QoS scheduling for MPEG video streams was proposed here. Simulation results show that our cross-layer architecture allows graceful video degradation while minimizing the mean packet delay and frame jitter. Finally, we outline future cross-layer research of multi-play over IP network.
Gender Inequality and Resistance : the Case of Portuguese Women in London

While they value the wage derived from their work in the labour force, married Portuguese migrant women in London do not necessarily find that this alters gender relations in the household to their satisfaction. There is little research on how women continue to struggle in spite of the changes wrought by their involvement in wage labour. Because women's day-to-day experiences are multifaceted, expressions of resistance to gender inequalities in the household can best be explored by examining both household and non-household relations, as well as other socio-political experiences. Married women express discontent with their lives in London by their orientation to return to Portugal. However, their involvement in the labour force has resulted in different return orientations among married and single women and men. I explore these differences by examining the social relations of the wage workplace and the household