Miracle-dz/UniFAR-FTUs huggingface dataset:
Gravitational Induced Chirality of Biology by Nuclear Magnetic Moments of 13 C and 17 O with 1 H, 14 N, and 25 Mg

Gravity is the one asymmetry on earth. Magnetism on earth is symmetry with N and S on earth. Electric field is also symmetrical with + and - on earth. Such symmetrical forces of electric and magnetic fields cannot as well explain the chiral nature of life’s molecules. But RBL theory of gravity better explains homochirality of biomolecules as gravity on earth is asymmetrical with mostly Br gravity on earth. In this work, RBL theory is developed more that Br gravity on earth is what broke the symmetry of chirality for one chirality for life on earth. Prior theories of homochirality do observe magnetic effects on physical processes, but magnetic fields on earth are not asymmetric, macroscopically. So different magnetic fields can alter chirality and the two polarities can manifest both chiralities. But why is there only one chirality in healthy organisms? RBL’s theory explains homochirality better by his gravity theory. Gravity on earth is asymmetrical. RBL theory determines earth’s gravity and its Br nature and irrational, fractional nature acts on stable isotopes of nonzero nuclear magnetic moments 13 C and 17 O in aqueous solvents on earth to organize organic compounds with preferred chirality for origin of life on earth. Such basis for life’s chiral origins is consistent with other aspects of RBL’s theory as isotopic enrichment in living organism can alter the primordial isotopic blueprint of chirality for altering metabolism for aging and disease.
Factors Influencing Smallholder Farmers’ Attitudes Towards Integrated Soil Fertility Management: Case Study of the Wanka Watershed, Northwestern Highlands of Ethiopia

Abstract This paper explores factors influencing smallholder farmers’ attitudes towards integrated soil fertility management (ISFM). ISFM is paramount to improve soil fertility for sustainable agricultural productivity, especially in contexts where smallholder agriculture is an important local livelihood and economic activity, as in many countries of the Global South. Alongside the development and availability of new technologies to enhance soil fertility, smallholder farmers’ attitudes towards these innovations in specific contexts are key to determining the extent and outcomes of their uptake. A better understanding of these is thus essential to inform measures to increase ISFM practices among smallholder farmers. This study aimed to assess farmers’ attitudes towards ISFM and the factors that determined them based on a case study of the Wanka watershed, northwestern Ethiopia, a major cereal-producing area. Using a mixed methods approach, data obtained from a household survey (146 respondents), focus group discussions, and key informant interviews were analyzed using descriptive statistics and a multiple regression model. The findings revealed that the attitudes of smallholder farmers towards ISFM in the study area were generally positive, as they considered ISFM compatible with agronomic principles and important to increase agricultural productivity sustainably. The extent of farmers’ farming experience, the length of time of applying chemical fertilizer, the number of livestock, and the size of plots were found to be significant predictors of attitudes towards ISFM. The study concludes that considering these factors can better inform interventions designed to enhance farmers’ choice of ISFM technologies for improved soil fertility management and sustainable crop production in the study area and other contexts.
Transcriptomics Provides Novel Insights into the Regulatory Mechanism of IncRNA HIF1 A-AS1 on Vascular Smooth Muscle Cells

Introduction Thoracic aortic aneurysm is a potentially fatal disease with a strong genetic contribution. The dysfunction of vascular smooth muscle cells (VSMCs) contributes to the formation of this aneurysm. Although previous studies suggested that long non-coding ribonucleic acid (RNA) hypoxia inducible factor 1 α-antisense RNA 1 (HIF1A-AS1) exerted a vital role in the progression and pathogenesis of thoracic aortic aneurysm, we managed to find a new regulatory mechanism of HIF1A-AS1 in VSMCs via transcriptomics. Methods Cell viability was detected by the cell counting kit-8 assay. Cell apoptosis was assessed by Annexin V-fluorescein isothiocyanate/propidium iodide double staining. Transwell migration assay and wound healing assay were performed to check the migration ability of HIF1A-AS1 on VSMCs. The NextSeq XTen system (Illumina) was used to collect RNA sequencing data. Lastly, reverse transcription-quantitative polymerase chain reaction confirmed the veracity and reliability of RNA-sequencing results. Results We observed that overexpressing HIF1A-AS1 successfully promoted apoptosis, significantly altered cell cycle distribution, and greatly attenuated migration in VSMCs, further highlighting the robust promoting effects of HIF1A-AS1 to thoracic aortic aneurysm. Moreover, transcriptomics was implemented to uncover its underlying mechanism. A total of 175 differently expressed genes were identified, with some of them enriched in apoptosis, migration, and cell cycle-related pathways. Intriguingly, some differently expressed genes were noted in vascular development or coagulation function pathways. Conclusion We suggest that HIF1A-AS1 mediated the progression of thoracic aortic aneurysm by not only regulating the function of VSMCs, but also altering vascular development or coagulation function.
The CCCma third generation AGCM and its extension into the middle atmosphere

The Canadian Centre for Climate Modelling and Analysis third generation atmospheric general circulation model (AGCM3) is described. The discussion summarizes the details of the complete physics package emphasizing the changes made relative to the second generation version of the model. AGCM3 is the underlying model for applications which include the IPCC fourth assessment, coupled atmosphere-ocean seasonal forecasting, the first generation of the CCCma earth system model (CanESM1), and middle-atmosphere chemical-climate modelling (CCM). Here we shall focus on issues related to an upwardly extended version of AGCM3, the Canadian Middle-Atmosphere Model (CMAM). The CCM version of CMAM participated in the 2006 WMO/UNEP Scientific Assessment of Ozone Depletion and issues concerning its climate such as the impact of gravity-wave drag, the modelling of a spontaneous QBO, and the seasonality of the breakdown of the Southern Hemisphere polar vortex are discussed here.
On feeding those hungry for praise: person praise backfires in children with low self-esteem Brummelman,

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Apollo 15 rake sample microbreccias and non-mare rocks: Bulk rock, mineral and glass electron microprobe analyses

Quantitative electron microprobe data of Apollo 15 nonmare rake samples are presented. Bulk analyses of lithic fragments in the nomare rocks (expressed in oxide weight-percent) and the corresponding CIPW molecular norms are given. The mineralogy of the rocks and lithic fragments are also given; structural formulae for complete analyses and molecular end-members for all mineral analyses are included. The mineral analyses include pyroxene, olivine, plagioclase, barian K-feldspar, spinel and ilmenite, cobaltian metallic nickel-iron as well as SiO2-K2O-rich residual glass. Electron micropobe analyses (oxide weight percent) of glasses in loose fines and microbreccia samples and their CIPW molecular norms are presented along with electron microprobe data on bulk, mineral, and matrix glass from chondrules.
1 Factors of influence on flood risk perceptions related to 1 Hurricane Dorian: an assessment of heuristics, time dynamics 2 and accuracy of risk perceptions 3

Flood damage caused by hurricanes is expected to rise globally due to climate and socio-economic 15 change. Enhanced flood preparedness among the coastal population is required to reverse this trend. The 16 decisions and actions taken by individuals are thought to be influenced by risk perceptions. This study 17 investigates the determinants that shape flood risk perceptions, as well as the factors that drive flood risk 18 misperceptions of coastal residents. We conducted a survey among 871 residents in flood-prone areas in Florida 19 during a five-day period in which the respondents were threatened to be flooded by Hurricane Dorian. This 20 approach allows for assessing temporal dynamics in flood risk perceptions during an evolving hurricane threat. 21 Among 255 of the same households, a follow-up survey was conducted to examine how flood risk perceptions 22 vary after Hurricane Dorian failed to make landfall in Florida. Our results show that the flood experience and 23 social norms have the most consistent relationship with flood risk perceptions. Furthermore, participants 24 indicated that their level of worry regarding the dangers of flooding decreased after the near-miss of Hurricane 25 Dorian, compared to their feelings of worry during the hurricane event. Based on our findings, we offer 26 recommendations for improving flood risk communication policies.
M etallomics R esearch M etallomics R esearch

In this study, artifi cial microparticles were used as pseudo-cells to select samples that can be used as substitutes for micro-droplet injection nebulizer (M-DIN) ICP-MS standards. The microparticles were selected on the basis that they should be comparable in size to human cells, have a small deviation in volume, and have diff erent elemental contents and pyrolysis properties. Polymer latex particles, magnetic latex particles, borosilicate glass particles, and straight polymethyl methacrylate particles were used. As a result, we succeeded in detecting the contained elements in polymer latex, magnetic latex and polymethyl methacrylate particles. In addition, focusing on Mg contained in all particles, we compared the correlation between the mass signal intensity by droplet ICP-MS and the average elemental content in a particle.
Biochemical Characterization, Antioxidant and Antiproliferative Activities of Different Ganoderma Collections

The aim of this study was to conduct a molecular and biochemical characterization and to compare the antioxidant and antiproliferative activities of four Ganoderma isolates belonging to Ganoderma lucidum (Gl-4, Gl-5) and Ganoderma resinaceum (F-1, F-2) species. The molecular identification was performed by ITS and IGS sequence analyses and the biochemical characterization by enzymatic and proteomic approaches. Antioxidant activity of the ethanolic extracts was compared by three different methods and their flavonoid contents were also analyzed by HPLC. The antiproliferative effect on U937 cells was determined by MTT assay. The studied mycelia differ both in the enzymatic activities and protein content. The highest content in total phenol and the highest antioxidant activity for DPPH free radical scavenging and chelating activity on Fe 2+ were observed with Gl-4 isolate of G. lucidum . The presence of quercetin, rutin, myricetin and morine as major flavonoids with effective antioxidant activity was detected. The ethanolic extracts from mycelia of G. lucidum isolates possess a substantial antiproliferative activity against U937 cells in contrast to G. resinaceum in which the antiproliferative effects were insignificant. This study provides the comparison between G. lucidum and G. resinaceum mycelial strains showing that G. resinaceum could be utilized to obtain several bioactive compounds.
Bipedal walking and push recovery with a stepping strategy based on time-projection control

In this paper, we present a simple control framework for online push recovery on biped robots with dynamic stepping properties. Owing to relatively heavy legs in our humanoid robot COMAN, we use a linear model called 3LP, which is composed of three pendulums to take swing and torso dynamics into account. Based on 3LP equations, we formulate discrete linear quadratic regulator (LQR) controllers and use a particular time-projection method to adjust footstep locations during the motion continuously. This process, which is based on pelvis and swing foot tracking errors, naturally considers swing dynamics and leads to leg-retraction properties. Suggested adjustments are added to the Cartesian 3LP gaits and converted into joint-space trajectories through inverse kinematics. Fixed and adaptive foot lift strategies are also used to ensure enough ground clearance in perturbed walking conditions. The proposed control architecture is robust, yet uses very simple state estimation and basic position tracking. We rely on series elastic actuators to absorb impacts while introducing simple laws to compensate for spring compressions. Extensive experiments on COMAN (real) and Atlas (simulated) robots demonstrate the functionality of different control blocks and prove the effectiveness of time-projection in extreme push recovery scenarios. We also show self-produced and emergent walking gaits when the robot is subject to continuous dragging forces. These gaits feature dynamic walking robustness with minimal reliance on the ankles and avoiding any active zero moment point (ZMP) control. The proposed architecture is therefore generic, computationally very fast and yet with no critical parameter to tune.
PROGRAM PENGEMBANGAN KEBERAGAMAAN PESERTA DIDIK DI SMA MELALUI KEGIATAN PEMBELAJARAN BERBASIS PAI DI LUAR KELAS (Studi Kasus di SMAN 5 Bandung)

Pendidikan mempunyai tujuan untuk menjadikan manusia bagus dalam bersikap, pengetahunnya semakin banyak dan keterampilannya berkembang serta bermanfaat. Begitu pula tujuan pendidikan agama Islam, supaya bisa menjadikan manusia insan kamil, dan menjadi manusia sejati yang menghambakan diri pada Allah secara total dan dapat hidup dengan masyarakat selaras dan mengelolanya sebagai pemimpin. Cita-citu itu akan terwujud dengan proses pembelajaran, guru mengajar dan siswa belajar, sehingga ada hasil belajar. Secara praktik untuk mencapai itu, pembelajaran dilakukan dengan serangkaan sistem, baik kurikuler intruksional normatif ataupun ko-kurikuler/ekstrakurikuler pembelajaran tidak normatif langsung. Pendidkan agama Islam memiliki peran penting untuk mewujudkan itu, baik sebagai mata pelajaran atau sebagai sebuah proses dan cara untuk menjadikan manuisa muslim, mukmin dan muhsin sejati yang akan tampak pada sikap dan perilaku keseharian pada lingkup pola keberagamaan. Oleh karena itu perlu program pengembangan keberagamaan peserta didik yang terencana, terukur, terevaluasi dan memiliki tingkat ketercapaian tinggi, terlebih dengan ruang lingkup sekolah umum atau SMA.
ENERGYSIM: techniques for advancing building energy education through immersive virtual reality (VR) simulation

An important practice for reducing the effects of global warming is the design and construction of energy-efficient buildings. In design education, the full comprehension of thermal behavior in buildings based on their geometry and material composition is required. The complexity of energy simulation principles, vis-a-vis the number of elements that impact the energy loads, their linkages, and their relationships to one another all combine to make this a challenging subject to absorb. Virtual Reality (VR) provides an immersive way to learn the concepts of building energy responses; however, the development of VR applications for education is difficult due to the knowledge, skill, and performance resource-related gaps. Unoptimized VR applications can adversely impact learning if user experiences are broken due to performance lags. This research, therefore, explores VR as a teaching tool for building energy education while showcasing the development process toward a visually accurate simulation and performant application. We developed EnergySIM; a multi-user VR building energy simulation prototype of the famous Farnsworth House. Using this prototype, we document rigorously tested development workflows for improved VR game performance, high visual fidelity, and user interaction, the three key factors which positively contribute to user knowledge retention. The study combines menu-driven interaction, virtual exploration, and miniature model manipulation approaches with the aim of testing user understanding and knowledge retention. Highlighted results provide reduced barriers of entry for educators towards developing higher quality educational VR applications. EnergySIM showcases pre-simulated building exterior surface heatmaps response from four seasons (winter, summer, fall, and spring) alongside an all-year-round sun-hour scenario. Four different material pre-simulated scenarios (single glazing, double glazing, concrete, and wood) for interior atmospheric temperature mapping are also explored. Preferred interaction methods are documented by allowing users’ visual appraisal of alternative building materials based on insulation capacity or resistance to heat flow (R-value). The significance of this work lies in its potential to revolutionize how students, designers, and instructors approach building energy education in today’s world. EnergySIM provides a hands-on and visually engaging learning experience towards the enhancement of knowledge retention and understanding. It pushes the boundaries of development for visual fidelity using geometry/mesh modeling input from various software into game engines and optimizing game performance using the HTC Vive Pro Eye and Meta Quest Pro headsets.
Reduction of matched and unmatched uncertainties for a class of nonlinear perturbed systems via robust control

The aim of this paper is to design a robust control for stabilization of a class of nonlinear perturbed system subject to matched and unmatched disturbances. Here, the concept of dynamic sliding mode control and the attractive ellipsoid method advantages are used to design a robust nonlinear control algorithm, which reduces considerably the perturbation effects. Hence, in finite time, the dynamic sliding mode control brings the system trajectory to a specific configuration. After this time, the controller reduces the perturbation effects by using the high‐gain control obtained in the attractive ellipsoid method. Thus, based on the solution of a specific matrix inequality, the feedback control of the system guarantees that the trajectory will be stabilized in the ultimate uniform bounded sense. To illustrate the theoretical results, a numerical example with a comparative study is introduced. Finally, the performance of the controller designed in this paper is tested on an electromechanical real‐time system.
JWST TECHNICAL REPORT

This report presents the analysis and results of the commissioning program NIS-013 (NGAS CAR-376, APT 1088). We describe the data and analysis used for updating the SIAF alignments from this commissioning program. We analyzed a total of 8 images (4 primary NIRISS + 4 parallel FGS1 exposures) to derive the SIAF alignment parameters V2Ref, V3Ref, and V3IdlYAngle of the NIRISS detector. These parameters were used to generate the SIAF xml file. The uncertainties of our calibrated parameters based on the 4 independent measurements are well below limits set by the mission requirements.
Can Kindergarten Meals Improve the Daily Intake of Vegetables, Whole Grains, and Nuts among Preschool Children? A Randomized Controlled Evaluation

Surveys have indicated that preschool children do not consume adequate amounts of vegetables, fruits, whole grains, and nuts. This cross-sectional intervention study aimed to investigate whether a meticulously crafted meal plan for children of kindergarten age (5–6 years) could effectively enhance their daily intake of nutritious foods. Ninety-four healthy children from six kindergartens were enrolled in the study and were randomly assigned to a prototype group (PG) and a control group (CG). The PG kindergartens (n = 4) received a prototype 5-day meal plan that included regulated portions of vegetables, fruits, whole grains, and nuts adhering to dietary guidelines. Conversely, the CG kindergartens (n = 2) adhered to their standard meal plan. Participants maintained their usual eating habits outside of kindergarten and during weekends. Using the dietary assessment tool Open Platform for Clinical Nutrition (OPEN), combined with a 7-day dietary record of food consumed inside and outside the kindergarten, the average daily intake of specific food groups was assessed and compared with the Dietary Guidelines for Children. A total of 57 participants completed the study, 40 from the PG and 17 from the CG. Among the PG participants, the average daily intake of vegetables, whole grains, and nuts compared with the guideline recommendations was significantly higher than in the CG. Notably, only meals consumed within the kindergarten setting significantly improved the overall intake, with the outside intake having no significant effect. This study underscores the vital role of a well-designed and precisely executed meal plan in kindergartens in improving children’s intake of healthy foods. The findings could help drive positive changes in child nutrition within educational environments.
An automated data quality control procedure applied to a mesoscale meteorological network

The mesoscale meteorological networks are composed by hundreds of stations providing continuous measurements of several meteorological variables. The large amount of observations collected at the data acquisition center must be checked using automatic Data Quality Control (DQC) tests. An automated DQC procedure describes the application of each individual test and the related decision making algorithms. The goal of a DQC procedure is to supply an efficient and powerful tool to the meteorological analyst.
Advancements in Chitosan-Based Nanoparticles for Pulmonary Drug Delivery

The evolution of respiratory diseases represents a considerable public health challenge, as they are among the leading causes of death worldwide. In this sense, in addition to the high prevalence of diseases such as asthma, chronic obstructive pulmonary disease, pneumonia, cystic fibrosis, and lung cancer, emerging respiratory diseases, particularly those caused by members of the coronavirus family, have contributed to a significant number of deaths on a global scale over the last two decades. Therefore, several studies have been conducted to optimize the efficacy of treatments against these diseases, focusing on pulmonary drug delivery using nanomedicine. Thus, the development of nanocarriers has emerged as a promising alternative to overcome the limitations of conventional therapy, by increasing drug bioavailability at the target site and reducing unwanted side effects. In this context, nanoparticles composed of chitosan (CS) show advantages over other nanocarriers because chitosan possesses intrinsic biological properties, such as anti-inflammatory, antimicrobial, and mucoadhesive capacity. Moreover, CS nanoparticles have the potential to enhance drug stability, prolong the duration of action, improve drug targeting, control drug release, optimize dissolution of poorly soluble drugs, and increase cell membrane permeability of hydrophobic drugs. These properties could optimize the performance of the drug after its pulmonary administration. Therefore, this review aims to discuss the potential of chitosan nanoparticles for pulmonary drug delivery, highlighting how their biological properties can improve the treatment of pulmonary diseases, including their synergistic action with the encapsulated drug.