Miracle-dz/UniFAR-FTUs huggingface dataset:
The Dating and Domestic Violence App Rubric: Synthesizing Clinical Best Practices and Digital Health App Standards for Relationship Violence Prevention Smartphone Apps

ABSTRACT Smartphones are used to both perpetrate and intervene in dating and domestic violence (DV). However, existing DV literature primarily evaluates technology as a tool for perpetration and emerging frameworks that measure eHealth app interventions have not yet considered DV. To address this gap, the Dating and Domestic Violence App Rubric assesses smartphone-based DV intervention apps along common eHealth app measures such as user responsiveness and security as well as DV-appropriateness – categories derived from eHealth intervention theory and evidence-based DV interventions. As proof of concept, 38 DV intervention apps for iPhone were measured using this rubric. K-means cluster analysis identified three clusters (high, medium, low). Apps targeting specific users or a specific intervention strategy tended to score higher overall. Findings suggest high-quality DV intervention apps may depend on active collaboration between stakeholders including app developers, DV advocates, and other professionals. Future research should expand this research to include additional DV apps and explore how individuals use smartphone apps to prevent or intervene in DV.
SIGNAL TRANSMISSION METHOD IN NETWORK-BASED AUDIO ANALYTICS SYSTEM

The subject matter of the article is аudio signal transmission method in network-based audio analytics system. The creation of a network-based audio analytics system leads to the emergence of new classes of load sources that transmit packetized sound data. Therefore, without constructing adequate mathematical models, it is impossible to build a well-functioning network-based audio analytics system. A fundamental question in traffic theory is the question of load source models. The development of an method for transmitting audio signals in a network-based audio analytics system becomes necessary. Based on this, the goal of the work is to create methods an method for transmitting audio signals in a network-based audio analytics system to ensure efficiency and accuracy in audio analytics. The following tasks were solved in the article: the formation of a model for the system's load sources, investigation of connection and traffic management, implementation of control and traffic monitoring functions in the network, research of methods to ensure the quality of audio signal transmission and the development of a method of transmitting an audio signal by virtual routes switching. To achieve these goals, the following methods are used: mathematical signal processing, data compression algorithms, optimization of network protocols, and the use of high-speed network connections. The obtained results include modeling of the system's load sources, examination of connection and traffic management, investigation of methods to ensure the quality of audio signal transmission and a method of transmitting an audio signal by virtual routes switching was proposed. In conclusion , the possibilities of using simulation modeling of nodes in the network-based audio analytics system are highly limited. This is explained by the fact that the acceptable level of information loss in data centers is very low. The use of the developed method enables effective control and processing of sound information in real-time. This method can find broad applications in various fields, including security, healthcare, management systems, and other industries where the analysis of audio signals is a crucial
Expanding the Boundaries of the Chemical Space of DNA Methyltransferase 1 Modulators

DNA methyltransferase 1 (DNMT1), one of the main epigenetic targets, is involved in the duplication of the DNA methylation pattern during replication, and it is essential for proper mammalian development. Small molecule DNMT1 modulators are attractive for biochemical epigenetic studies and have the potential to become drugs. So far, more than five hundred small molecules have been reported as DNMT1 inhibitors. However, only a limited number of DNMT1 activators have been disclosed because, at least in part, DNMT1 activators are typically regarded as negative data in virtual screening campaigns or optimization projects. This manuscript aims to report the chemical structures and biological activity of small molecules that increase the enzymatic activity of DNMT1. Results of the biochemical experimental assays are discussed. It was found that small molecule activators have a large variety of chemical scaffolds but share pharmacophore features. Visual analysis of the chemical space and multiverse based on molecular fingertips supported that activators are structurally diverse. This is the first report of eight small molecules that increase the enzymatic activity of DNMT1 by more than 400% in an enzymatic-based assay. The outcome warrants further investigation of the epigenetic activity of the compounds in a counter-screen assay, e.g., cell-based and in vivo context.
Environmental Study on Mining Area Living Environment Satisfaction Evaluation-Taking an Example of Huainan City

At the same time, the environmental and health impacts of mining on surrounding communities have been major concerns to governments, the general public and stakeholder organizations and individuals. Mining area residents living environment satisfaction has a close correlation with mining area residents’ actual needs. In order to rationally evaluate living environment satisfaction situation on mining area residents, the measure index system were constructed and an attribute mathematical evaluation model was set up. The weights of the indexes were determined by the AHP, and coal mining area residents living environment satisfaction was evaluated by setting the confidence rule according to the attribute measure values of each indicator and multiple indicators. A practical case examines this method’s validity. The evaluation results indicated that the attribute mathematical model is an effective method for mining area residents living environment satisfaction evaluation, which provides a relatively scientific and rational evaluation tools for solving such problems.
Phylogenetic Characterization of Salmonella enterica Serovar Typhimurium and its Monophasic Variant Isolated from Food Animals in Japan

Salmonella enterica subsp. enterica serovar Typhimurium and its monophasic variant ( Salmonella 4,[5],12:i:-) are two of the most frequently isolated serovars in food animals worldwide. Especially, human and swine infections by Salmonella 4,[5],12:i:- have increased considerably in Western countries since the mid-1990s. Although bovine and swine salmonellosis by Salmonella 4,[5],12:i:- has been increasing in Japan, the genetic background of the serovar has been unclear. In our study, whole genome sequence (WGS)-based phylogenetic analysis was performed to reveal the characteristics of Salmonella Typhimurium and Salmonella 4,[5],12:i:- isolated in Japan. Nine distinctive clades were identified and clonal replacements were observed several times in the last four decades. Among the nine clades, clade 9, which is a multidrug-resistant and predominant clone after 2010, has similar characteristics to the European clone that has been a major threat to public and animal health worldwide in recent years. Furthermore, the two distinctive clades in clade 9 were identified by phylogenetic analysis. Each clade has diverged through microevolution mediated by the acquisition or deletion of mobile genetic elements such as plasmids, prophages, composite transposons, and integrative and conjugative elements. The present review focuses on WGS-based phylogenetic studies of Salmonella Typhimurium and Salmonella 4,[5],12:i:- isolated from food animals in Japan.
Solanum aculeastrum Dunal berries: Phytochemical profiling and GC-MS analysis of methanolic extract and n-hexane, dichloromethane, ethyl acetate and n-butanol fractions

Background: Solanum aculeastrum is reportedly used in several diseases including gonorrhea, bronchitis, jigger infestations and wounds, and cancers. We conducted an exhaustive phytochemical and GC-MS profiling of its methanol extract and solvents’ fractions. Methods: About 4500g of dried berries of S. aculeastrum was extracted with methanol, part of which was partitioned into fractions of n-hexane, dichloromethane, ethyl acetate, n-butanol and aqueous fractions. These fractional preparations were subjected to phytochemical and GC-MS profiling except aqueous fraction. Results: The percentage yield of 430.69g of methanol extract of berries of S.aculeastrum was 9.57%w/w, while the yields of dried 19.4g of n-hexane, 38.4g of DCM, 6.4g of ethyl acetate, 81.03g of n-butanol and 21.2g of the freeze-dried aqueous fractions were 7.08%w/w, 14.03 %w/w, 2.33%w/w, 29.60%w/w and 7.74%w/w respectively. The relative presence of glycosides, alkaloids, tannins, flavonoids, terpenoids, phenols, saponins were confirmed except quinones. GC-MS profiling of methanol extract identified 32 compounds including alkane, alcohol, carbohydrate, fatty acids, terpenoids, glycerides, vitamins and some unclassified compounds. 25 compounds including terpenoids, alkene, fatty acids, vitamin and unclassified compounds were identified in n-hexane fractions. The DCM fraction yielded 20 compounds including isoprenoid, terpenoids, amino acids, carboxylic acid and unclassified compounds. 22 compounds were identified in ethyl acetate fraction including phenol, fatty acids, alcohol, terpenoids, glycerolipid and unclassified compounds. The n-butanol fraction yielded 11 compounds including fluorinated aromatic substance, hormonal antineoplastic and a non-steroidal anti-inflammatory agent. Conclusion: This study has further elaborated on the bioactive compounds in berries of S. aculeastrum, to aid robust understanding of its pharmacologic activities.
Patulin removal in fruit-based products using probiotics and potential probiotics

Patulin (PAT) is a prevalent mycotoxin frequently found in fruit and its derivatives, such as apple, pear, and juices. Despite worldwide attempts to diminish the levels of PAT at every stage of the fruit production process, its contamination rate remains high. This mycotoxin is worrisome due to its potential adverse impacts on human health. Eating PAT-contaminated fruit can lead to acute and chronic health issues. It is established, by the Joint FAO/WHO, a maximum tolerable daily intake for PAT at 0.4 µg/kg/day. Therefore, monitoring for PAT contamination is essential for the safe consumption of fruits and fruit-related products such as juices, purees, ciders, jams, marmalades, vinegar, and dried fruits. PAT has physiochemical properties that enable its survival in cold, hypoxic, acidic, or high-temperature conditions. Ideally, detoxification procedures should aim to reduce the level of toxins to safe levels whilst preserving the nutritional and palatable values of the treated commodity. There are several physical, chemical, and biological techniques available for PAT detoxification. However, while physical and chemical methods can remove PAT, they may also lower the nutrient quality and organoleptic properties of the food. Biological detoxification is an effective, environmentally friendly, easy, and cost-effective method, as established by existing research. It has proven efficacy in food safety research and regulatory compliance programs. Probiotics have been studied for their potential to reduce PAT in foods via different mechanisms (such as adsorption, degradation, and transformation), as well as all their health-beneficial effects. In this review, the reduction of PAT in fruit-based products using probiotics or potential probiotics is widely discussed.
Analisis Karakteristik Air Tanah Berdasarkan Data Isotop Stabil 18O dan 2H serta Kimia Air di Dataran Aluvial Kota Semarang

Kota Semarang merupakan salah satu kota metropolitan yang berada di utara Pulau Jawa dengan jumlah penduduk mencapai 1,6 juta jiwa. Perkembangan kepadatan penduduk cenderung berdampak pada kebutuhan air bersih yang semakin meningkat. Saat ini hampir 80% kebutuhan air bersih di Kota Semarang diperoleh dari air tanah. Tujuan penelitian ini adalah menentukan karakteristik air tanah di Kota Semarang. Metode penelitian menggunakan analisis data isotop stabil 18O dan 2H dan kimia air melalui perhitungan nilai Chlorite Bicarbonate Ratio (CBR) dan analisis diagram Piper. Sampel air tanah yang digunakan mencapai 30 sampel. Litologi daerah penelitian berupa aluvium dan batupasir. Hasil penelitian diperoleh tipe air tanah di daerah penelitian terdiri dari tipe air NaHCO3, NaCl, CaHCO3, Na2SO4, dan MgHCO3 dengan tingkat pengaruh air laut dibedakan dalam 3 kelompok yang mencakup air tanah terintrusi sedikit-sedang, air tanah terintrusi agak tinggi, dan air tanah terintrusi tinggi. Analisis isotop 18O dan 2H menunjukkan bahwa air tanah di daerah penelitian dibagi menjadi 3 kelompok yaitu Kelompok I (18O -4, 585‰), Kelompok II (18O -5,070 ‰) dan Kelompok III (18O -5,451 - -6,044‰) serta memiliki nilai d-excess positif yang sebagian besar nilainya >10.
Green Disposal of Waste Bisphenol A

Abstract Bisphenol A (BPA) is an important precursor for polycarbonates and epoxy resins that are used to make products that many would consider essential for modern living. Unfortunately, BPA is an endocrine disrupter and more and more evidence is being uncovered about its negative effects on humans as well as on organisms in the environment. Sustainable chemistry means we take everything into account in designing a chemical process: the risks, the costs, the benefits, and so on. BPA is not likely to be replaced by a less toxic chemical in the foreseeable future, nor is our society willing to give up valuable polycarbonate products. As part of sustainable green chemistry, we want to assure that any toxic chemicals that leave a manufacturing plant pose a minimal risk to the environment. Using a green method to clean up effluent before it is released into the environment would be ideal. In this report, little bluestem seeds are shown to be capable of degrading BPA in aqueous solutions. This gives them the potential to be used in reducing the amount of BPA that may be in effluent. Additionally, an enzyme was isolated that was responsible for degrading BPA and this could also have potential for the treatment of effluent.
DETERMINATION OF THE ANTIHYPERTENSIVE DRUGS CAPTOPRIL, ATENOLOL, AND METOPROLOL IN DOSAGE FORMS

Three antihypertensive drugs Captopril (CPL), Atenolol (ATL), and Metoprolol (MTL) have been estimated sensitively and selectively by a single spectrophotometric method using neutral red dye NLR. The method is based on oxidation of the drugs by known excess of N-bromosuccinamide (NBS) in the first reaction step followed by the oxidation of NLR dye with the exceed ed amount of NBS, as the concentration of the drug compounds increase, the color of the dye increase, the dye exhibits absorbance peak at 523 nm. The linearity range was from 1 to 10 µg/ml for the three drugs, the molar absorptivity values were 2.1164 × 105, 1.9202× 104, and 57.934× 104 l.mol-1.cm-1 for CPL, ATL, and MTL respectively, the sensitivity index of Sand’ll were 0.0102, 0.0138, and 0.01182 µg/cm2 for CPL, ATL, and MTL respectively. LOD values for the three drugs ranged from 0.00405 to 0.00547 and LOQ values were ranged from 0.0135 to 0.0182 respectively, the method exhibits good applicability to the dosage forms and high confidence as compared with standard method and standard addition method.
Pig exploitation at Neolithic Çayönü Tepesi (southeastern Anatolia)

L'analyse d'une longue sequence d'ossements d'animaux provenant du site Neolithique de Cayonu Tepesi, en Anatolie, permet ici de comprendre le changement effectue dans la relation entre l'homme et le porc dans le cadre d'un continuum chasse-elevage. Les nombreux ossements decouverts sur le site temoignent d'une exploitation intensive du porc.
Analysis of physics learning in elementary schools and the need for professional development: Is STEM education training necessary for elementary school teachers?

This study aims to explore pedagogical approaches and students’ engagement during STEM teaching. As many as 215 elementary school teachers in West Java were involved in this research. Those involved consisted of 161 women and 49 men. The majority of teachers have an elementary school teacher education background (87%), 7% have other educational backgrounds (Science Education/Mathematics Education/Social Education/Language Education), and the remaining 6% are in the sciences. The instrument used in this study was a closed questionnaire with 20 items from a Likert scale survey. The results of the study show that 50% of elementary school teachers very rarely use experimental approaches and problem-based learning when teaching STEM content. More than 60% of teachers also very rarely use the inquiry approach in teaching the four contents. The approach that is often used by teachers in teaching STEM is a collaborative and integrated approach. In addition, the survey results also show that more than 50% of students are very rarely involved in inquiry and engineering practice activities when learning about STEM content. The analysis of professional development needs showed that the majority of elementary school teachers have never received a professional development program regarding STEM education. In fact, the majority of teachers have a positive attitude towards the coaching program, which has an impact on increasing their competence. Apart from that, the results of this research also show that there is a lack of external support (from universities, educational practitioners, and researchers) for teachers in coaching programs. These findings provide evidence that teachers still need to receive training on pedagogical approaches that are relevant to integrated STEM education. The existence of training on STEM education is expected to improve the quality of STEM learning in the classroom. Thus, students' involvement in scientific and engineering practice when learning STEM becomes more dominant.
Foreign Aids, Human Capital and Economic Growth

This research work examines the impacts of foreign aids and human capital on economic growth of African oil and non-oil producing countries. Adopting the time series data from 2000 to 2021, the study employs Westerlund Error Correction Based panel cointegration test to investigate the impacts of Physical Capital (FA, GCF, FDI), Human Capital (EDU, HLT) and Policy Variables (REV, EXR) on Gross Domestic Product growth rate (GDPgr). Findings from results of the study affirms that there is a long-term co-movement between the GDPgr and the explanatory variables (FA, GCF, FDI, EDU, HLT, REV, EXR) of both African oil and non-oil producing countries. The study also reveals that foreign aids are better effectively put into use in the African non-oil producing countries than in the oil producing countries. Findings in the study equally confirm that financial resources in the African non-oil producing countries are better efficiently spent on human capital and domestic investment than in the African oil producing countries. The study further shows that revenue generation and foreign exchange earnings stimulate growth better in the African oil producing countries than the non-oil countries counterparts in Africa.
female soccer players: Intersession reliability and the fatiguing effects of soccer-specific

Low levels of leg stiffness and reduced leg stiffness when fatigue is present compromise physical performance and increase injury risk. The purpose of this study was to (a) determine the reliability of leg stiffness measures obtained from contact mat data and (b) explore age-related differences in leg stiffness following exposure to a soccer-specific fatigue protocol in young female soccer players. 37 uninjured female youth soccer players divided into 3 sub-groups based on chronological age (U13, U15 and U17 year olds) volunteered to participate in the study. Following baseline data collection during which relative leg stiffness, contact time, flight time was collected, participants completed an age-appropriate soccer-specific fatigue protocol (SAFT 90 ). Upon completion of the fatigue protocol, subjects were immediately re-tested. Inter-session reliability was acceptable and could be considered capable of detecting worthwhile changes in performance. Results showed that leg stiffness decreased in the U13 year olds, was maintained in the U15 age group and increased in the U17 players. Contact times and flight times did not change in the U13 and U15 year olds, but significantly decreased and increased respectively in the U17 age group. The data suggests that age-related changes in the neuromuscular control of leg stiffness are present in youth female soccer players. Practitioners should be aware of these discrepancies in neuromuscular responses to soccer-specific fatigue, and should tailor training programs to meet the needs of individuals which may subsequently enhance performance and reduce injury risk.
Physical Retting of Apple (Malus Domestica) Peels, Dehydrated Jackfruit (Artocarpus Heterophyllus) Rinds, and Mango (Mangifera Indica) Peels for Alternative Multipurpose Paper Component

This study was conducted to determine the potential of apple (Malus domestica) peels, dehydrated jackfruit (Artocarpus heterophyllus) rinds, and mango (Mangifera indica) peels physically retted for alternative multipurpose paper component. This study used Complete Randomized Design with 4 treatments for each, with commercial multipurpose paper (CMP) as the control. There are 4 replicates for each treatment and 3 samples for each replicate, amounting to 12 samples per treatment. Physically retted M. domestica peels (AP), dehydrated A. heterophyllus rinds (JFR), and M. indica peels (MP), were subjected to pulp-making process and paper processing through mould and deckle method. It was found that the durability in terms of time (seconds) it takes for the papers made from JFR T3 (200g JFR + 100g cornstarch) and MP T1 (pure MP) to break down into pieces when submerged in water is comparably similar with CMP (α=0.05). It is concluded that based on comparative durability to CMP, JFR and MP can potentially be used as a component in making multipurpose paper. Recommendations such as determining the effects of the fibers physically retted from JFR and MP on the quality of the multipurpose papers produced is encouraged.
Implementation of a Comprehensive Eco-Riparian Concept to Landscape Design of Water Source Area in Macari Village, Batu City

The eco-riparian concept application on the riverside is one of the programs of the Ministry of Environment and Forestry of the Republic of Indonesia. The water source in Macari Village is one of the suppliers of raw water discharge in the Brantas watershed. Residential and industrial areas currently surround Macari Village Water sources, so it decreases the water quality, and pollution is often found due to industrial and household waste contamination. This research aims to find comprehensive eco-riparian concept design solutions to conserve water resources. By using a combined methodology between case studies and literature reviews, comprehensive eco-reparation design criteria were found, such as wetland restoration by using the terraced pond, vegetation management of the water bodies, ground covers, cliff retaining, aesthetic support vegetation, wastewater management, and drainage plans so it will not pollute the water sources. The development to support the area's vision is manifested in architectural design with ecological and historical characteristics. This design criteria is translated into a holistic visualization of the area to produce a coherent, functional, and aesthetic design. With the design result, all regional development visions are expected to be realized at the location.