Miracle-dz/UniFAR-FTUs huggingface dataset:
Touch & Compose: Physical User Interface for Application Composition in Smart Environments

In this paper, we sketch a model for interaction between smart environment and their inhabitants. We also introduce Touch & Compose, a concept for composing applications which utilizes this interaction model. The basic idea of Touch & Compose is to assemble applications from the resources that the user has selected manually by touching them with her mobile terminal. Resources (devices, services, files, etc.) are represented with icons attached to real environment objects. RFID tags are placed under the icons; they contain data identifying the resources. The mobile terminal is equipped with an RFID reader. The touched icons are collected in the mobile terminal's resource stack; an application is composed from the resources in the stack either automatically or when requested by the user. Some resources collected from the environment can be stored permanently in the mobile terminal. The stack allows also sharing resources with other users at the environment. We also present software architecture for implementing the Touch & Compose concept and suggest a GUI for the mobile terminal.
Title The multiple periodic structure antenna design

Abstract— In this paper, the generalized analysis and novel application of the multiple periodic (MP) structure are proposed. Both transmission and radiation performances of one dimensional MP structures are studied. The dispersion relations are analyzed from both layered media (distributive) and lumped circuits aspects. Regarding each aspect, both non-dispersive (conventional) and dispersive (composite right/left-handed (CRLH)) materials are discussed. It is found that with the increase of the periodicity, multiple stopbands are open up due to the reflections. Meanwhile the space harmonic modes’ separation distance is reduced in the dispersion diagrams. It leads to simultaneously dualistic (rightand left-handed) radiation performance and multi-beam property, and more abundant radiation modes are excited at relatively lower frequencies comparing with conventional periodic structures. A general dispersion relation formula and a general Bragg condition for MP structures are derived. The dispersion relation is simply described by the former, and the latter helps to indicate the stopbands locations and engineer the dispersion relation consequently. Applications of MP structures to phase reversal (PR) antennas are also presented in this paper. They experimentally verifies both transmission and radiation characteristics of MP structures. In each analysis, single (SP), double (DP) and triple periodic (TP) structures are presented and compared. This work would also contribute to designs of multi-band devices.
Recent advances in understanding the structure of nicotinic acetylcholine receptors

Nicotinic acetylcholine receptors (nAChRs), members of the Cys‐loop ligand‐gated ion channels (LGICs) superfamily, are involved in signal transduction upon binding of the neurotransmitter acetylcholine or exogenous ligands, such as nicotine. nAChRs are pentameric assemblies of homologous subunits surrounding a central pore that gates cation flux, and are expressed at the neuromuscular junction and in the nervous system and several nonneuronal cell types. The 17 known nAChR subunits assemble into a variety of pharmacologically distinct receptor subtypes. nAChRs are implicated in a range of physiological functions and pathophysiological conditions related to muscle contraction, learning and memory, reward, motor control, arousal, and analgesia, and therefore present an important target for drug research. Such studies would be greatly facilitated by knowledge of the high‐resolution structure of the nAChR. Although this information is far from complete, important progress has been made mainly based on electron microscopy studies of Torpedo nAChR and the high‐resolution X‐ray crystal structures of the homologous molluscan acetylcholine‐binding proteins, the extracellular domain of the mouse nAChR α1 subunit, and two prokaryotic pentameric LGICs. Here, we review some of the latest advances in our understanding of nAChR structure and gating. © 2009 IUBMB IUBMB Life, 61(4): 407–423, 2009
Flavonoids in fruits and vegetables after thermal and nonthermal processing: A review

ABSTRACT Consumers currently demand more nutritious food, which is minimally processed and naturally produced. Flavonoids are one of the major plant metabolites found throughout the plant kingdom, especially in fruits and vegetables. Flavonoids exert tremendous positive effects on health and protect against various diseases. Fruits and vegetables are difficult to store for a long period, owing to their perishable nature even at low temperatures. Therefore, processing is necessary to prolong their shelf lives and increase nutritional values. Thermal processing has been used in the food sector since ancient times. However, nonthermal processing has become more attractive to consumers and product developers recently, owing to the retention of beneficial health properties after nonthermal processing. The present review will address the effects of thermal and nonthermal processing methods such as blanching, drying, high-pressure processing, ultrasound, pulsed electric field, and ultraviolet irradiation on total and individual flavonoid content in fruits and vegetables. In addition, this text will elucidate the stability characteristics as well as bioavailability, cytotoxicity, and transformations of flavonoids during thermal and nonthermal treatments.
Fixed Gonadotropin-Releasing Hormone Antagonist Protocol Versus Flexible Progestin-Primed Ovarian Stimulation Protocol in Patients With Asynchronous Follicular Development During Controlled Ovulation Stimulation: A Retrospective Study

Protocols utilizing gonadotropin-releasing hormone (GnRH) antagonists have emerged as mainstream procedures for ovarian stimulation; however, GnRH increases the risk for periodic cancellation of embryos. Therefore, this study aimed to compare the pregnancy outcomes of a fixed GnRH antagonist protocol and a flexible progestin-primed ovarian stimulation (fPPOS) protocol in patients with asynchronous follicular development during controlled ovulation stimulation and to explore the feasibility of converting patients undergoing a fixed GnRH antagonist protocol to an fPPOS protocol. This was the first retrospective study exploring the fPPOS protocol in patients with asynchronous follicular development, and it was conducted in a public reproductive medicine center from January to December 2020. We included infertile women. All participants were scheduled to undergo administration of a GnRH antagonist on the fifth day of controlled ovulation stimulation. The study group included 129 women who were converted from the fixed GnRH antagonist protocol to the fPPOS protocol for their asynchronous follicular development, while the antagonist group consisted of 258 women (ratio 1:2) who proceeded with a fixed GnRH antagonist protocol. On the second or third day of the menstrual period, 100–300 IU/day gonadotropin injections were administered. For patients who were converted to the fPPOS protocol, medroxyprogesterone acetate tablets at 10 mg/day were started on the fifth day of stimulation or when only one leading follicle reached 14 mm and the other follicles were ≤10 mm in diameter, whichever came first. The rates of embryo implantation, clinical pregnancy, and early pregnancy loss were obtained. The number of oocytes retrieved and the number of high-quality embryos in the antagonist group were significantly higher than those in the fPPOS group (P = 0.039 and P = 0.025, respectively). No significant differences in the rates of embryo implantation, clinical pregnancy, and early pregnancy loss were observed between the two groups. Our study found that in patients who were scheduled for administration of GnRH antagonists but presented with asynchronous follicular development on the fifth stimulation day, it was feasible to switch to the fPPOS protocol.
A Critical Review of Studies of Discrimination Against Workers with Disabilities

Discrimination's dynamic nature means that no single theory, method, data or study should be relied upon to assess its magnitude, causes, or remedies. Despite some gains in our understanding, these remain active areas of debate among researchers, practitioners and policymakers. The specially commissioned papers in this volume, all by distinguished contributors, present the full range of issues related to this complex and challenging problem.
Construct and Predictive Validity of the Repeatable Battery for the Assessment of Neuropsychological Status in the Evaluation of Stroke Patients

To evaluate the construct and predictive validity of a brief neuropsychological assessment battery, consecutive admissions to a hospital receiving inpatient treatment for stroke were tested with the Repeatable Battery for Assessment of Neuropsychological Status (RBANS) and other neuropsychological measures. Discriminant and convergent validity were adequate for the Language, Visuospatial/Constructional, Immediate Memory and Delayed Memory indices in the RBANS, but weaker for the Attention Index. Twelve months later, 36 discharged patients were contacted by telephone and interviewed using a battery of functional outcome measures. RBANS Total Score predicted cognitive disability as measured by the Functional Independence Measure. Individual indices from the RBANS also predicted instrumental activities of daily living (IADLs) as measured by the Frenchay Activity Index and participation restrictions as measured by the Craig Handicap Assessment and Reporting Technique. The present findings suggest that the RBANS can be a useful tool in the neuropsychological evaluation of inpatients with stroke. Thanks to Brooke Donnelley, Jeremy Clorfene and Michael Ostrom for their extensive assistance in this project. Thanks also to Christopher Randolph for his assistance with this manuscript. Supported by the US Department of Education, National Institute on Disability and Rehabilitation Research, grant H133B30024 through the Rehabilitation Research and Training Center on Enhancing Quality of Life of Stroke Survivors
Using the Microsoft Translator Hub at The Church of Jesus Christ of Latter-day Saints

The Church of Jesus Christ of Latter-day Saints undertook an extensive effort at the beginning of this year to deploy machine translation (MT) in the translation workflow for the content on its principal website, www.lds. org. The objective of this effort is to reduce by at least 50% the time required by human translators to translate English content into nine other languages and publish it on this site. This paper documents the experience to date, including selection of the MT system, preparation and use of data to customize the system, initial deployment of the system in the Church’s translation workflow, post-editing training for translators, the resulting productivity improvements, and plans for future deployments.
Synthesizing Novel Pairs of Image and Text

Generating novel pairs of image and text is a problem that combines computer vision and natural language processing. In this paper, we present strategies for generating novel image and caption pairs based on existing captioning datasets. The model takes advantage of recent advances in generative adversarial networks and sequence-to-sequence modeling. We make generalizations to generate paired samples from multiple domains. Furthermore, we study cycles -- generating from image to text then back to image and vise versa, as well as its connection with autoencoders.
Teknik Seyir Hizmetlerinde Kaynakların Simülasyon Modellemesi Yöntemiyle Optimizasyonu: Römorkör Park Yeri Seçimi

Suyollarinda, kiyi tesislerinde ve acik deniz yapilarinda deniz araclarinin manevra emniyeti ve verimliligi icin kilavuzluk, romorkorculuk ve palamar hizmetlerine ihtiyac duyulmaktadir. Bu hizmetler genel olarak “teknik seyir hizmetleri” (technical-nautical services) olarak isimlendirilmektedir. Teknik seyir hizmetleri kapsaminda gemi ve deniz araclari icin sunulan romorkorculuk hizmetlerinin verimliligi, teskilatlarin isletme maliyeti ve hizmet kalitesi acisindan son derece onemli bir konudur. Romorkor hizmetinin sunulma bicimi, hizmet talebini yerine getirme zamani, hizmet sahasinin buyuklugu, cekme kuvveti yeterliligi, romorkor sayisi ve manevra kabiliyeti bu hizmetin baslica kalite olcutleri arasindadir. Bu arastirma, 2011 yilinda Gemport Kilavuzluk ve Romorkorculuk Hizmetleri Teskilatinda Emniyet Kulturunu Guclendirme Calismalari sirasinda teskilatin ihtiyacina yonelik olarak gelistirilmistir. Arastirma, teskilatin Gemlik Korfezi’nde sunmus oldugu teknik seyir hizmetleri kapsaminda kullanmis oldugu iki adet romorkorun “park” yerlerinin belirlenmesi amaciyla gelistirilmistir. Arastirmada gemi trafigi varis zamani verileri, gemi olculerinin dagilimi, limanlardaki yuk ellecleme zamanlarina ait veriler ve hizmetin verilme sekli konusunda yapilan gorusmelerden elde edilen bilgiler kullanilarak bir algoritma gelistirilmistir. Bu algoritma Promodel simulasyon programinda test edilerek optimum romorkor park yerleri belirlenmistir. Romorkorculuk hizmetinin verildigi sahada belirlenen bu en uygun park yeri noktalari, romorkorlerin park yerinden hizmet verme noktasina gidis suresi ile hizmet verdikten sonra da park yerine donecekleri sure toplaminin optimizasyonuyla saglamistir.
Pleural infection: what we need to know but don’t

Purpose of review Pleural infection remains a common and difficult problem to manage in the 21st century. Despite advances in modern healthcare, the rising incidence and mortality of empyema highlights a need for better understanding of the disease and more effective strategies in its diagnosis and treatment. Recent findings Recent studies have progressed our knowledge and understanding of the bacteriology and pathophysiology of pleural infection. However, rather than providing firm conclusions, examination of current literature provokes several unanswered questions on most aspects of the disease. Summary This review aims to challenge traditional current concepts and approaches to clinical practice in pleural infection, to stimulate debate and research into potential novel future therapies.
1DLBP and PCA for face recognition

A new algorithm for face recognition is proposed in this work, this algorithm is mainly based on LBP texture analysis in one dimensional space 1DLBP and Principal Component Analysis PCA as a technique for dimensionalities reduction. The extraction of the face's features is inspired from the principal that the human visual system combines between local and global features to differentiate between people. Starting from this assumption, the facial image is decomposed into several blocks with different resolution, and each decomposed block is projected in one dimensional space. Next, the proposed descriptor 1DLBP is applied for each projected block. Then, the resulting vectors will be concatenated in one global vector. Finley, Principal Component Analysis is used to reduce the dimensionalities of the global vectors and to keep only the pertinent information for each person. The experimental results applied on AR database have showed that the proposed descriptor 1DLBP combined with PCA have given a very significant improvement at the recognition rate and the false alarm rate compared with other methods of face recognition, and a good effectiveness against to deferent external factors as: illumination, rotations and noise.
“One Man’s Flood Defense Is Another Man’s Flood”: Relating Through Water Flows in Gloucestershire, England

ABSTRACT Presenting voices and observations from flood-affected people in Gloucestershire, United Kingdom, this article analyzes the relationships that flooding engenders through the material dynamics of water, and argues that flooding illustrates how particular social relations are simultaneously hydrological, and vice versa. It presents the variability of water flows in people’s environments, and the local differentiation of normal and exception floods. By outlining the residents’ concern about drainage, their hydrosociality, that is, an understanding of relatedness through and with water, is sketched. It is explored how these hydrosocial relations become intensely political, where insiders and outsiders, and beneficiaries and losers, are configured in relation to water and flood risk. Finally, the article shows how pollution in flooding emerges out of perceived disorderly flows, when water moves into a place along the wrong trajectory and embodying the wrong characteristics. Where one person’s or group’s defenses can easily turn into another’s increased risk, water flows and social relations are intimately entwined.
ACCUMULATION OF DOBZHANSKY‐MULLER INCOMPATIBILITIES WITHIN A SPATIALLY STRUCTURED POPULATION

Abstract. — A simple, deterministic analysis predicts that accumulation of Dobzhansky‐Muller incompatibilities by a spatially structured population strongly depends on the number of negative interactions of an allele. If an allele can be incompatible with alleles at only one locus, incompatibilities accumulate linearly with time. In contrast, if an allele can participate in multiple pairwise incompatibilities with alleles at different loci, the expected number of incompatibilities eventually increases quadratically.
The roles of NADPH oxidase and phospholipases A2 in oxidative and inflammatory responses in neurodegenerative diseases

Reactive oxygen species (ROS) are produced in mammalian cells through enzymic and non‐enzymic mechanisms. Although some ROS production pathways are needed for specific physiological functions, excessive production is detrimental and is regarded as the basis of numerous neurodegenerative diseases. Among enzymes producing superoxide anions, NADPH oxidase is widespread in mammalian cells and is an important source of ROS in mediating physiological and pathological processes in the cardiovascular and the CNS. ROS production is linked to the alteration of intracellular calcium homeostasis, activation of Ca2+‐dependent enzymes, alteration of cytoskeletal proteins, and degradation of membrane glycerophospholipids. There is evolving evidence that ROS produced by NADPH oxidase regulate neuronal functions and degrade membrane phospholipids through activation of phospholipases A2 (PLA2). This review is intended to cover recent studies describing ROS generation from NADPH oxidase in the CNS and its downstream activation of PLA2, namely, the group IV cytosolic cPLA2 and the group II secretory sPLA2. A major focus is to elaborate the dual role of NADPH oxidase and PLA2 in mediating the oxidative and inflammatory responses in neurodegenerative diseases, including cerebral ischemia and Alzheimer’s disease. Elucidation of the signaling pathways linking NADPH oxidase with the multiple forms of PLA2 will be important in understanding the oxidative and degradative mechanisms that underline neuronal damage and glial activation and will facilitate development of therapeutic intervention for prevention and treatment of these and other neurodegenerative diseases.
Entrepreneurship, Economic Risks, and Risk Insurance in the Welfare State: Results with OECD Data 1978±93

Abstract We find evidence in the OECD cross-country data to support the Knightian view that non-diversifiable economic risks shape equilibrium entrepreneurship in an occupational choice model. Differential social insurance of entrepreneurial and labor risk is found to be statistically significant and detrimental to entrepreneurship. The crowding-out effect of public production of private goods on entrepreneurship dominates the crowding-in effect of public production of public goods in the OECD data. Weak evidence is found for the proposition that the rate of entrepreneurship is related to the degree of income inequality and to the union power in the economy. The results also suggest that in countries with low GDP per capita ratio, self-employment is high.
Identification of Down's syndrome critical locus gene SIM2-s as a drug therapy target for solid tumors

We report here a cancer drug therapy use of a gene involved in Down's syndrome. Using bioinformatics approaches, we recently predicted Single Minded 2 gene (SIM2) from Down's syndrome critical region to be specific to certain solid tumors. Involvement of SIM2 in solid tumors has not previously been reported. Intrigued by a possible association between a Down's syndrome gene and solid tumors, we monitored SIM2 expression in solid tumors. Isoform-specific expression of SIM2 short-form (SIM2-s) was seen selectively in colon, prostate, and pancreatic carcinomas but not in breast, lung, or ovarian carcinomas nor in most normal tissues. In colon tumors, SIM2-s expression was seen in early stages. Antisense inhibition of SIM2-s expression in a colon cancer cell line caused inhibition of gene expression, growth inhibition, and apoptosis. The administration of the antisense, but not the control, oligonucleotides caused a pronounced inhibition of tumor growth in nude mice with no major toxicity. Our findings provide a strong rationale for the genes-to-drugs paradigm, establish SIM2-s as a molecular target for cancer therapeutics, and may further understanding of the cancer risk of Down's syndrome patients.
Catalyst: Piloting Capabilities for more Transparent Text Analytics

The surge and value of unstructured text is attracting substantial research and industry attention. Subsequently we are witnessing novel techniques and algorithms that are performing increasingly sophisticated text mining tasks. However the majority of such techniques are opaque, making it hard to trace the provenance of the analytical task on hand. We propose Catalyst, a framework to automatically transform, enrich and expose text into a linked graph-based layer to enable more transparent processing and access to the text elements. In brief, Catalyst extracts text dependencies, performs sentiment analysis, detects semantic relatedness, and links the text elements into a semantic triple-store that enables an easy access to the text entities through direct query functionalities. We plan to evaluate the performance of Catalyst by processing a dataset of user reviews around the dimensions of an evaluation model deployed in the context of e-government services.
Systems analysis of plant cell wall degradation by the model filamentous fungus Neurospora crassa

The filamentous fungus Neurospora crassa is a model laboratory organism, but in nature is commonly found growing on dead plant material, particularly grasses. Using functional genomics resources available for N. crassa, which include a near-full genome deletion strain set and whole genome microarrays, we undertook a system-wide analysis of plant cell wall and cellulose degradation. We identified approximately 770 genes that showed expression differences when N. crassa was cultured on ground Miscanthus stems as a sole carbon source. An overlap set of 114 genes was identified from expression analysis of N. crassa grown on pure cellulose. Functional annotation of up-regulated genes showed enrichment for proteins predicted to be involved in plant cell wall degradation, but also many genes encoding proteins of unknown function. As a complement to expression data, the secretome associated with N. crassa growth on Miscanthus and cellulose was determined using a shotgun proteomics approach. Over 50 proteins were identified, including 10 of the 23 predicted N. crassa cellulases. Strains containing deletions in genes encoding 16 proteins detected in both the microarray and mass spectrometry experiments were analyzed for phenotypic changes during growth on crystalline cellulose and for cellulase activity. While growth of some of the deletion strains on cellulose was severely diminished, other deletion strains produced higher levels of extracellular proteins that showed increased cellulase activity. These results show that the powerful tools available in N. crassa allow for a comprehensive system level understanding of plant cell wall degradation mechanisms used by a ubiquitous filamentous fungus.