Miracle-dz/UniFAR-FTUs huggingface dataset:
Single-mode displacement sensor

We show that one can determine both parameters of a displacement acting on an oscillator with an accuracy which scales inversely with the square root of the number of photons in the oscillator. Our results are obtained by using a grid state as a sensor state for detecting small translations in phase space (displacements). Grid states were first proposed in (see this https URL ) for encoding a qubit into an oscillator: an efficient preparation protocol of such states, using a coupling to a qubit, was developed in (see this https URL ). We compare the performance of the grid state with the quantum compass or cat code state and place our results in the context of the two-parameter quantum Cramer-Rao lower bound on the variances of the displacement parameters. We show that the accessible information about the displacement for a grid state increases with the number of photons in the state when we measure and prepare the state using a phase estimation protocol. This is in contrast with the accessible information in the quantum compass state which we show is always upper bounded by a constant, independent of the number of photons. We present numerical simulations of a phase estimation based preparation protocol of a grid state in the presence of photon loss, nonlinearities and qubit measurement, using no post-selection, showing how the two effective squeezing parameters which characterize the grid state change during the preparation. The idea behind the phase estimation protocol is a simple maximal-information gain strategy.
Variations in genetic diversity in cultivated Pistacia chinensis

Identification of the evolution history and genetic diversity of a species is important in the utilization of novel genetic variation in this species, as well as for its conservation. Pistacia chinensis is an important biodiesel tree crop in China, due to the high oil content of its fruit. The aim of this study was to uncover the genetic structure of P. chinensis and to investigate the influence of intraspecific gene flow on the process of domestication and the diversification of varieties. We investigated the genetic structure of P. chinensis, as well as evolution and introgression in the subpopulations, through analysis of the plastid and nuclear genomes of 39 P. chinensis individuals from across China. High levels of variation were detected in the P. chinensis plastome, and 460 intraspecific polymorphic sites, 104 indels and three small inversions were identified. Phylogenetic analysis and population structure using the plastome dataset supported five clades of P. chinensis. Population structure analysis based on the nuclear SNPs showed two groups, clearly clustered together, and more than a third of the total individuals were classified as hybrids. Discordance between the plastid and nuclear genomes suggested that hybridization events may have occurred between highly divergent samples in the P. chinensis subclades. Most of the species in the P. chinensis subclade diverged between the late Miocene and the mid-Pliocene. The processes of domestication and cultivation have decreased the genetic diversity of P. chinensis. The extensive variability and structuring of the P. chinensis plastid together with the nuclear genomic variation detected in this study suggests that much unexploited genetic diversity is available for improvement in this recently domesticated species.
MASK EFFECTS ON COSMOLOGICAL STUDIES WITH WEAK-LENSING PEAK STATISTICS

With numerical simulations, we analyze in detail how the bad data removal, i.e., the mask effect, can influence the peak statistics of the weak-lensing convergence field reconstructed from the shear measurement of background galaxies. It is found that high peak fractions are systematically enhanced because of the presence of masks; the larger the masked area is, the higher the enhancement is. In the case where the total masked area is about 13% of the survey area, the fraction of peaks with signal-to-noise ratio ν ⩾ 3 is ∼11% of the total number of peaks, compared with ∼7% of the mask-free case in our considered cosmological model. This can have significant effects on cosmological studies with weak-lensing convergence peak statistics, inducing a large bias in the parameter constraints if the effects are not taken into account properly. Even for a survey area of 9 deg2, the bias in (Ωm, σ8) is already intolerably large and close to 3σ. It is noted that most of the affected peaks are close to the masked regions. Therefore, excluding peaks in those regions in the peak statistics can reduce the bias effect but at the expense of losing usable survey areas. Further investigations find that the enhancement of the number of high peaks around the masked regions can be largely attributed to the smaller number of galaxies usable in the weak-lensing convergence reconstruction, leading to higher noise than that of the areas away from the masks. We thus develop a model in which we exclude only those very large masks with radius larger than 3′ but keep all the other masked regions in peak counting statistics. For the remaining part, we treat the areas close to and away from the masked regions separately with different noise levels. It is shown that this two-noise-level model can account for the mask effect on peak statistics very well, and the bias in cosmological parameters is significantly reduced if this model is applied in the parameter fitting.
ON THE DISAPPEARANCE OF THE BROAD-LINE REGION IN LOW-LUMINOSITY ACTIVE GALACTIC NUCLEI: THE ROLE OF THE OUTFLOWS FROM ADVECTION DOMINATED ACCRETION FLOWS

The broad-line region (BLR) disappears in many low-luminosity active galactic nuclei (AGNs), the reason of which is still controversial. The BLRs in AGNs are believed to be associated with the outflows from the accretion disks. Most of the low-luminosity AGNs contain advection-dominated accretion flows (ADAFs) which are very hot and have a positive Bernoulli parameter. ADAFs are therefore associated with strong outflows. We estimate the cooling of the outflows from the ADAFs and find that the gases in such hot outflows cannot always be cooled efficiently by bremsstrahlung radiation. The ADAF may co-exist with the standard disk, i.e., the inner ADAF connects to the outer thin accretion disk at radius Rd,tr in the sources accreting at slightly lower than the critical rate (). For the ADAFs with Lbol/LEdd ≳ 0.001, a secondary small inner cold disk is suggested to co-exist with the ADAF due to the condensation process. We estimate the Compton cooling of the outflow, of which the soft seed photons either come from the outer cold disk or the secondary inner cold disk. It is found that the gas in the outflow far from the ADAF may be efficiently cooled to form BLR clouds due to the soft seed photons emitted from the cold disks, provided the transition radius of the ADAF to the outer cold disk is small [rd,tr = Rd,tr/(2GM/c2) ≲ 20] or/and the secondary small cold disk has a luminosity Lsd ≳ 0.003 LEdd. The BLR clouds can still be formed in the outflows from the outer cold thin disks, if the transition radius rtr is not very large. For the sources with Lbol/LEdd ≲ 0.001, the inner small cold disk is evaporated completely in the ADAF and the outer thin accretion disk may be suppressed by the ADAF, which leads to the disappearance of the BLR. The physical implications of this scenario on the double-peaked broad-line emitters are also discussed.
Spinel harzburgite–derived silicate melts forming sulfide-bearing orthopyroxenite in the lithosphere. Part 2: Sulfide compositions and their chalcophile and highly siderophile trace element signatures

In the first article, we have reported petrological data for a new, glass-bearing orthopyroxenite vein cutting a sub-arc mantle xenolith from Kamchatka. As similar veins from the West Bismarck arc, this orthopyroxenite is sulfide-rich and formed by cooling of parental melts derived by partial melting of spinel harzburgite sources. Here, I report new data for the abundances of major base metals and chalcophile and highly siderophile trace elements in vein sulfides from the two localities. Kamchatka vein sulfides are all Cu-poor monosulfide solid solution (MSS). West Bismarck veins contain MSS and a ternary (Fe, Cu, Ni)S solid solution (“xSS”), which ranges between MSS and intermediate solid solution (ISS) in composition. Sulfides follow Ni and Cu enrichment trends and have chondrite-normalized platinum-group element (PGE) patterns with elevated Pt relative to Os, Ir, Ru, and Rh. Pt alloys are frequently associated with sulfides and vugs formed from hydrothermal fluids, which also contain metallic Fe and wüstite. Vein sulfides, ranging from Fe-rich MSS (ca. 1,050–1,100°C) to xSS (≤850°C) through Ni-rich MSS, were formed in a sulfide liquid line of descent under oxygen and sulfur fugacity conditions (fO2 and fS2) down to one log unit below the fayalite–magnetite–quartz and close to the Pt-PtS buffers, respectively. The Ni and Cu enrichment trends in MSS are consistent with cooling and fractionation of Ni-rich and Cu-poor sulfide liquids (original atomic ∑metal/S∼0.9), which will finally solidify as xSS or ISS. Chondrite-normalized Pt/Pd>1 in some of the sulfides is a signature of spinel harzburgite sources. Because it occurs at relatively low fS2, the crystallization sequence of these sulfide liquids is accompanied by the formation of abundant PGE alloys and other metallic phases. Melts derived from spinel harzburgite sources can be originally oxidized to carry up to ∼2,600 ppm S (predominantly as S6+) and follow a sulfide-undersaturated evolution trend, until they are rapidly cooled to crystallize as orthopyroxenite dykes or sills. There, S6+-Fe2+ redox reactions with host rocks, together with the production of high-Mg# andesite derivatives with low S solubility and high-temperature, hydrothermal fluids at decreasing fO2 and fS2, will lead to the local precipitation of abundant sulfides and alloys.
Knowing the rules can effectively enhance plastic waste separation on campus

Although proper plastic waste separation is critical to efficient disposal, people do not always comply with designated rules, possibly resulting from a lack or misunderstanding of the correct rules related to local variability. Accordingly, this study aimed to understand how learning the plastic waste separation rules changed college students' behavior on campus, besides how said knowledge spreads across campuses. To evaluate the impact, quasi-experiments were conducted from May to July 2022, including a hybrid of before–after and treatment–control designs. The treatment group included college students at a university in Japan (N = 295 and 188 for the first and second surveys, respectively); the control group also included college students in the same region (N = 395 and 219 for the first and second surveys, respectively). Before learning the rules, 12.8% of the treatment group followed the correct rules. After acquiring the rules, this number increased to 38.3%. The difference-in-differences analysis verified its statistically significant improvement over the control group. Structural equation models based on the theory of planned behavior before and after learning the rules revealed that the intention–behavior gap was bridged by the learning, indicating limitations due to a lack of knowledge. The best–worst scaling showed that habits should be targeted to further improve separation behaviors; whereas an egocentric network analysis demonstrated that knowledge spread among peers, albeit to a limited extent. In summary, this study revealed that knowing designated rules is a simple but effective approach to enhancing plastic waste separation in a certain context.
Characterization of B cells in lupus erythematosus skin biopsies in the context of different immune cell infiltration patterns

Cutaneous lesions in lupus erythematosus (LE) subtypes are heterogenous. In line with the heterogeneity of the clinical presentation, the underlying lesional inflammation in LE skin samples is defined by different immune cell infiltrates. Pathophysiologically, lesional inflammation is driven by autoreactive cytotoxic T cells, targeting keratinocytes; plasmacytoid dendritic cells (pDCs), producing large amounts of interferon (IFN); and B cells, whose function in cutaneous LE is still unclear. This study aims to (a) classify inflammatory patterns with regard to the dominating cell type or cytokine expression and (b) investigating the specific role of B cells in LE skin lesions. Therefore, the immunohistological expression of inflammatory surrogates (CD20, CD123, MXA) in skin samples of n = 119 LE (subtypes: subacute cutaneous LE, chronic discoid LE, chilblain LE, LE tumidus, other LE) and n = 17 patients with inflammatory skin diseases (atopic dermatitis, psoriasis) were assessed. Samples were classified with regard to inflammatory groups. In addition multiplex-immunohistochemical analyses of n = 17 LE skin samples focusing on lesional B cells were conducted. In this study, we show that cutaneous lesions present with eight different inflammatory groups dominated by B cells, pDCs, a strong IFN expression, or overlapping patterns. Altogether, LE subtypes show heterogenous infiltration regardless of LE subtype, certain subtypes display a preference for infiltration groups. Furthermore, lesional B cells either form diffuse infiltrates or pseudofollicular structures, wherein they show antigen-presenting and T cell-activating properties. Altogether, in the light of emerging targeted therapeutic options, we suggest histological assessment in regard to B-cell or pDC preponderance to allow tailored treatment decisions.
A systematic review of [68Ga]Ga-DOTA-FAPI-04 and [18F]FDG PET/CT in the diagnostic value of malignant tumor bone metastasis

Objective This study aims to perform a systemic analysis of [68Ga]Ga-DOTA-FAPI-04 positron emission tomography (PET)/computerized tomography (CT) and [18F]FDG PET/CT for the diagnosis of malignant tumor bone metastasis based on existing clinical evidence. Methods This systematic review followed the guidelines of the Preferred Reporting Project (PRISMA) for systematic reviews and meta-analysis. This is a retrospective study of articles published in PubMed. Embase was searched online from the start of May 2022. The main endpoints were the maximum standardized uptake value and the tumor-to-background ratio to determine the examination performance of [68Ga]Ga-DOTA-FAPI-04 and [18F]FDG for bone transfer stoves. Based on the entry and discharge standards, two researchers extracted documents and data and then performed the quality evaluation. Results A total of eight studies on the metastasis of malignant tumors on bone were included, which involved 358 patients in the final analysis. Conclusion [68Ga]Ga-DOTA-FAPI-04 showed better detection performance for bone metastasis. The sensitivity of [68Ga]Ga-DOTA-FAPI-04 for the diagnosis of the primary tumor was higher than that of [18F]FDG, whereas the specificity of [18F]FDG was higher than that of [68Ga]Ga-DOTA-FAPI-04. However, further randomized controlled trials and prospective clinical trials are warranted to compare the diagnostic performance of [68Ga]Ga-DOTA-FAPI-04 PET/CT and [18F]FDG PET/CT. Systematic review registration https://www.crd. york.ac. uk/PROSPERO/, identifier (CRD42022313019)
18-22 cm VLBA Faraday rotation studies of six AGN jets

The formation of relativistic jets in active galactic nuclei (AGN) is related to accretion on to their central supermassive black holes, and magnetic fields are believed to play a central role in launching, collimating and accelerating the jet streams from very compact regions out to kiloparsec or megaparsec scales. In the presence of helical or toroidal magnetic fields threading the AGN jets and their immediate vicinity, gradients in the observed Faraday rotation measures are expected due to the systematic change in the line-of-sight component of the magnetic field across the jet. We have analysed total intensity, linear polarization, fractional polarization and Faraday rotation maps based on Very Long Baseline Array data obtained at four wavelengths in the 18-22 cm range for six AGN (OJ 287, 3C 279, PKS 1510-089, 3C 345, BL Lac and 3C 454.3). These observations typically probe projected distances out to tens of parsecs from the observed core, and are well suited for Faraday rotation studies due to the relatively long wavelengths used and the similarity of the structures measured at the different wavelengths. We have identified statistically significant, monotonic, transverse Faraday rotation gradients across the jets of four of these six sources, as well as a tentative transverse Faraday rotation gradient across the jet of OJ 287, providing evidence for the presence of toroidal magnetic fields, which may be one component of helical magnetic fields associated with these AGN jets.
Salinity and hydraulic retention time induce membrane phospholipid acyl chain remodeling in Halanaerobium congolense WG10 and mixed cultures from hydraulically fractured shale wells

Bacteria remodel their plasma membrane lipidome to maintain key biophysical attributes in response to ecological disturbances. For Halanaerobium and other anaerobic halotolerant taxa that persist in hydraulically fractured deep subsurface shale reservoirs, salinity, and hydraulic retention time (HRT) are important perturbants of cell membrane structure, yet their effects remain poorly understood. Membrane-linked activities underlie in situ microbial growth kinetics and physiologies which drive biogeochemical reactions in engineered subsurface systems. Hence, we used gas chromatography–mass spectrometry (GC–MS) to investigate the effects of salinity and HRT on the phospholipid fatty acid composition of H. congolense WG10 and mixed enrichment cultures from hydraulically fractured shale wells. We also coupled acyl chain remodeling to membrane mechanics by measuring bilayer elasticity using atomic force microscopy (AFM). For these experiments, cultures were grown in a chemostat vessel operated in continuous flow mode under strict anoxia and constant stirring. Our findings show that salinity and HRT induce significant changes in membrane fatty acid chemistry of H. congolense WG10 in distinct and complementary ways. Notably, under nonoptimal salt concentrations (7% and 20% NaCl), H. congolense WG10 elevates the portion of polyunsaturated fatty acids (PUFAs) in its membrane, and this results in an apparent increase in fluidity (homeoviscous adaptation principle) and thickness. Double bond index (DBI) and mean chain length (MCL) were used as proxies for membrane fluidity and thickness, respectively. These results provide new insight into our understanding of how environmental and engineered factors might disrupt the physical and biogeochemical equilibria of fractured shale by inducing physiologically relevant changes in the membrane fatty acid chemistry of persistent microbial taxa. GRAPHICAL ABSTRACT Salinity significantly alters membrane bilayer fluidity and thickness in Halanaerobium congolense WG10.
On isolated millisecond pulsars formed by the coalescence of neutron stars and massive white dwarfs

Abstract This paper uses population synthesis to investigate the possible origin of isolated millisecond pulsars as born from the coalescence of a neutron star and a white dwarf. Results show that the galactic birth rate of isolated millisecond pulsars is likely to lie between 5.8×10−5 yr−1 and 2.0×10−4 yr−1, depending on critical variables, such as the stability of mass transfer via the Roche lobe and the value of kick velocity. In addition to this, this paper estimates that the solar mass of isolated millisecond pulsars can range from 1.5 and 2.0 Mʘ, making them more massive than other ‘normal’ pulsars. Finally, the majority of isolated millisecond pulsars in our simulations have spin periods ranging from several to 20 ms, which is consistent with previous observations.
Focusing on cyclin-dependent kinases 5: A potential target for neurological disorders

Cyclin-dependent kinases 5 (Cdk5) is a special member of proline-directed serine threonine kinase family. Unlike other Cdks, Cdk5 is not directly involved in cell cycle regulation but plays important roles in nervous system functions. Under physiological conditions, the activity of Cdk5 is tightly controlled by p35 or p39, which are specific activators of Cdk5 and highly expressed in post-mitotic neurons. However, they will be cleaved into the corresponding truncated forms namely p25 and p29 under pathological conditions, such as neurodegenerative diseases and neurotoxic insults. The binding to truncated co-activators results in aberrant Cdk5 activity and contributes to the initiation and progression of multiple neurological disorders through affecting the down-stream targets. Although Cdk5 kinase activity is mainly regulated through combining with co-activators, it is not the only way. Post-translational modifications of Cdk5 including phosphorylation, S-nitrosylation, sumoylation, and acetylation can also affect its kinase activity and then participate in physiological and pathological processes of nervous system. In this review, we focus on the regulatory mechanisms of Cdk5 and its roles in a series of common neurological disorders such as neurodegenerative diseases, stroke, anxiety/depression, pathological pain and epilepsy.
Dependence of the bright end of composite galaxy luminosity functions on cluster dynamical states

Luminosity function of cluster galaxies provides a fundamental constraint on galaxy evolution in cluster environments. By using the bright member galaxies of a large sample of rich clusters identified from Sloan Digital Sky Survey, we obtain the bright end of composite luminosity functions of cluster galaxies, and study their dependence on cluster dynamical state. After a redshift-evolution correction of absolute magnitude, the luminosity function of member galaxies can be well fitted by a Schechter function when the brightest cluster galaxies (BCGs) are excluded. The absolute magnitudes of BCGs follow a Gaussian function with a characteristic width of about 0.36 mag. We find that the luminosity function of galaxies in more relaxed clusters has a fainter characteristic absolute magnitude (M_{\ast}), and these clusters have fewer bright non-BCG member galaxies but a brighter BCG. Our results suggest the co-evolution of galaxy population with cluster dynamical state and somewhat support the hierarchical formation scenario of the BCGs.
Two-dimensional bipolar junction transistors

Recent development in fabrication technology of planar two-dimensional (2D) materials has introduced the possibility of numerous novel applications. Our recent analysis has revealed that by definition of p-n junctions through appropriate patterned doping of 2D semiconductors, ideal exponential I–V characteristics may be expected. However, the theory of 2D junctions turns out to be very different to that of standard bulk junctions. Based on this theory of 2D diodes, we construct for the first time a model to describe 2D bipolar junction transistors (2D-BJTs). We derive the small-signal equivalent model, and estimate the performance of a 2D-BJT device based on graphone as the example material. A current gain of about 138 and maximum threshold frequency of 77 GHz, together with a power-delay product of only 4 fJ per 1 μm lateral width is expected at an operating voltage of 5 V. In addition, we derive the necessary formulae and a new approximate solution for the continuity equation in the 2D configuration, which have been verified against numerical solutions.