Miracle-dz/UniFAR-FTUs huggingface dataset:
Challenges for the Dutch welfare state

The Dutch welfare state is under pressure. Ageing makes public finances unsustainable and globalisation tends to worsens the position of low-skilled workers. At the same time, welfare state institutions seem insufficiently adapted to changed socio-cultural circumstances and cause inactivity among elderly workers, women and social benefit recipients. To prepare for the future and maintain social cohesion, the Dutch government aims to raise the quantity and quality of employment. This paper explores how welfare state reform can contribute to these goals, thereby taking into account the key functions that the welfare state fulfils in terms of equality, security and smoothing. We quantify the effects of various reforms on the labour market and the income distribution by using an applied general equilibrium model for the Netherlands. The paper further develops three comprehensive welfare state reforms for the Netherlands and assesses its implications. 1 CPB and Erasmus University. Correspondence: CPB Netherlands Bureau for Economic Policy Analysis, P.O. Box 80510, 2508 GM The Hague, The Netherlands, e-mail: radm@cpb.nl. This paper is a summary of a more elaborate study on Reinventing the Welfare State published in De Mooij (2006).
STANlite – A Database Engine for Secure Data Processing at Rack-Scale Level

Intel's novel Software Guard eXtensions (SGX) enable secure and trusted execution of services, thereby paving the way to outsource sensitive data processing to external data centers. While SGX promises trusted execution close to native speed, frequent I/O operations and memory usage beyond a hardware-dependent threshold of currently 92 MiB result in substantial performance degradation. For memory-intensive workloads such as key-value stores and databases these penalties can be prohibitively high. We present STANlite – an in-memory database engine for SGX-enabled secure data processing in rack-scale environments. STANlite performs efficient user-level paging, whenever a database workload requires more space than the performance-friendly in-memory state size. Furthermore, STANlite smartly combines the properties of Remote Direct Memory Access (RDMA) and SGX to reduce the overhead of network-based I/O operations. While SGX usually provides confidentiality and integrity at the same time, STANlite enables a purely integrity preserving data management mode for additional performance. Finally, STANlite features a small trusted computing base and is memory-efficient, as it extends SQLite, a database for embedded use. We evaluated STANlite in terms of query response time. It outperforms a vanilla SGX-based SQLite version by 1.79x for microbenchmarks and 2.44x for TPC-C.
LSU Digital Commons LSU Digital Commons Multiple origins of green blood in New Guinea lizards Multiple origins of green blood in New Guinea lizards

Several species of lizards from the megadiverse island of New Guinea have evolved green blood. An unusually high concentration of the green bile pigment biliverdin in the circulatory system of these lizards makes the blood, muscles, bones, tongue, and mucosal tissues bright green in color, eclipsing the crimson color from their red blood cells. This is a remarkable physiological feature because bile pigments are toxic physiological waste products of red blood cell catabolism and, when chronically elevated, cause jaundice in humans and all other vertebrates. Although these lizards offer a promising system to examine the evolution of extraordinary physiological characteristics, little is known about the phylogenetic relationships of green-blooded lizards or the evolutionary origins of green blood. We present the first extensive phylogeny for green-blooded lizards and closely related Australasian lizards using thousands of genomic regions to examine the evolutionary history of this unusual trait. Maximum likelihood ancestral character state reconstruction supports four independent origins of green blood. Our results lay the phylogenetic foundation necessary to determine the role, if any, of natural selection in shaping this enigmatic physiological trait as well as understanding the genetic, proteomic, and biochemical basis for the lack of jaundice in those species that have independently evolved green blood.
What to expect in next generation RAN architecture: A survey

5G research is being carried out around the world to meet growing application requirements. Under such background, the research on evolution of Radio Access Network (RAN) architecture has become one of the hottest topics. In this paper we first review the current research results of the main participants, including 3GPP, IEEE, NGMN, IMT-2020, China Mobile, and SK Telecom. Then, the main features of next generation RAN architecture and relevant technologies are discussed.
prescribing errors : a before-and-after audit Impact of a standard medication chart on

http://qshc.bmj. com/content/18/6/478.full. html Updated information and services can be found at: These include: References http://qshc.bmj. com/content/18/6/478.full. html#ref-list-1 This article cites 34 articles, 17 of which can be accessed free at: service Email alerting box at the top right corner of the online article. Receive free email alerts when new articles cite this article. Sign up in the Notes
Buffering Data in a Time-Delayed Neuron-like Regenerative Optoelectronic Pulse Generator

Buffering of optical signals is desirable to avoid congestion of information traffic and realize efficient optical interconnects [1]. All-optical buffer memories have been proposed based on slow-light delay lines [2], or using the Kerr nonlinearity on a standard silica optical fiber [3], providing functionalities such as all-optical storage and reshaping. However, for realistic applications an optical buffer has to be compact for on-chip integration, which rules out most existing schemes, as they are not easily scalable to a millimeter size footprint and the writing process is often complex and costly. Novel configurations that combine the robustness of semiconductor nano-optoelectronic devices with the wide bandwidth of photonic sources offer significant advantages because they can provide small size, high-speed and low cost alternatives to the currently proposed all-optical buffers.
Resource Creation Towards Automated Sentiment Analysis in Telugu (a low resource language) and Integrating Multiple Domain Sources to Enhance Sentiment Prediction

Understanding the polarity or sentiment of a text is an important task in many application scenarios. Sentiment Analysis of a text can be used to answer various questions such as election prediction, favouredness towards any product etc. But the sentiment analysis task becomes challenging when it comes to low resource languages because the basis of learning sentiment classifiers are annotated datasets and annotated datasets for non-English texts hardly exists. So for the development of sentiment classifiers in Telugu, we have created corpora "Sentiraama" for different domains like movie reviews, song lyrics, product reviews and book reviews in Telugu language with the text written in Telugu script. In this paper, we describe the process of creating the corpora and assigning polarities to them. After the creation of corpora, we trained the classifiers that yields good classification results. Typically a sentiment classifier is trained using data from the same domain it is intended to be tested on. But there may not be sufficient data available in the same domain and additionally using data from multiple sources and domains may help in creating a more generalized sentiment classifier which can be applied to multiple domains. So to create this generalized classifier, we used the sentiment data from the above corpus from different domains. We first tested the performance of sentiment analysis models built using single data source for both in-domain and cross-domain classification. Later, we built sentiment model using data samples from multiple domains and then tested the performance of the models based on their classification. Finally, we compared all the three approaches based on the performance of the models and discussed the best approach for sentiment analysis.
Systèmes et protocoles de télé-réveil appliqués à l'optimisation énergétique des réseaux de capteurs sans fil. (Wake-up radio systems and protocols for optimizing energy consumption in wireless sensor networks)

De nos jours, une forte croissance des objets connectes est constatee, depassant meme la population mondiale. Devant l'ampleur de ce phenomene, l'efficacite energetique des objets communicants est une serieuse problematique. La maximisation de leur duree de vie est requise pour assurer une qualite de service. Dans cette optique, les travaux de cette these visent a optimiser la consommation energetique des communications sans fil dans un reseau de capteurs. Le tele-reveil, un concept imagine depuis une dizaine d'annees, consiste au declenchement du reveil du noeud communicant par un signal radio a distance. Par defaut, le noeud reste en mode veille de facon permanente a tres basse consommation. Au besoin, il peut etre reveille a la demande par un signal radio specifique. Ainsi, la consommation energetique du module radio est grandement reduite par l'ecoute passive du canal en mode veille. Ce principe de tele-reveil necessite toutefois le developpement de nouvelles architectures materielles associees a des protocoles de communication adaptes et innovants. Malgre les propositions recentes, le niveau de maturite technologique n'a pas encore ete atteint sur ce sujet. Par consequent, un systeme de tele-reveil est propose dans cette these, en incluant une caracterisation theorique de ses performances. Le recepteur de tele-reveil consomme 363 nW en mode veille contre 49,8 µW en mode de reception. De plus, deux nouveaux protocoles de tele-reveil DoRa et DC-DoRa sont proposes avec une evaluation de leurs performances par simulation. Les resultats obtenus montrent que ces protocoles de tele-reveil diminuent fortement l'energie consommee par le module radio, en comparaison des protocoles MAC actuellement utilises dans les reseaux de capteur. Enfin, la mise en œuvre experimentale du systeme et des protocoles de tele-reveil a permis de mesurer les performances reelles de notre approche dans un environnement de surecoute et d'interference.
EEG Cortical Potential Imaging of Brain Electrical Activity by means of Parametric Projection Filters

SUMMARY The objective of this study was to explore suitable spatial filters for inverse estimation of cortical potentials from the scalp electroencephalogram. The effect of incorporating noise covariance into inverse procedures was examined by computer simulations. The parametric projection filter,which allows inverse estimation with the presence of information on the noise covariance,was applied to an inhomogeneous three-concentricsphere model under various noise conditions in order to estimate the cortical potentials from the scalp potentials. The present simulation results suggest that incorporation of information on the noise covariance allows better estimation of cortical potentials,than inverse solutions without knowledge about the noise covariance,when the correlation between the signal and noise is low. The method for determining the optimum regularization parameter,which can be applied for parametric inverse techniques, is also discussed.
C-HTS: A Concept-based Hierarchical Text Segmentation approach

Hierarchical Text Segmentation is the task of building a hierarchical structure out of text to reflect its sub-topic hierarchy. Current text segmentation approaches are based upon using lexical and/or syntactic similarity to identify the coherent segments of text. However, the relationship between segments may be semantic, rather than lexical or syntactic. In this paper we propose C-HTS , a Concept-based Hierarchical Text Segmentation approach that uses the semantic relatedness between text constituents. In this approach, we use the explicit semantic representation of text, a method that replaces keyword-based text representation with concept-based features, automatically extracted from massive human knowledge repositories such as Wikipedia. C-HTS represents the meaning of a piece of text as a weighted vector of knowledge concepts, in order to reason about text. We evaluate the performance of C-HTS on two publicly available datasets. The results show that C-HTS compares favourably with previous state-of-the-art approaches. As Wikipedia is continuously growing, we measured the impact of its growth on segmentation performance. We used three different snapshots of Wikipedia from different years in order to achieve this. The experimental results show that an increase in the size of the knowledge base leads, on average, to greater improvements in hierarchical text segmentation.
High tRNA Transferase NSUN2 Gene Expression is Associated with Poor Prognosis in Head and Neck Squamous Carcinoma

ABSTRACT NSUN2 is a tRNA methyltransferase and plays an important role in cell development via modifying RNA methylation. We aimed to evaluate the expression of NSUN2 and its prognostic value in HNSCC. Random-effects model of meta-analysis shows 1.99-folds (95% CI: 1.89–2.09) upregulation of NSUN2 expression in HNSCC versus normal tissues. Patients with high NSUN2 levels had approximately 22 months shorter overall survival, and had a higher mortality risk than those with low one (p-trend = 0.020). In conclusion, NSUN2 is a potential independent prognostic marker and may be a potential therapeutic target in HNSCC.
Pre-soaking of hamstring grafts reduces risk of infection after ACL-reconstruction. A prospective study including 1000 patients

Aims and Objectives: Post-operative infection of the knee is one of the major concerns following ACL-reconstruction. The purpose of this study was to investigate whether the pre-soaking of hamstring grafts in vancomycin reduces the incidence of post-operative infection. Materials and Methods: This prospective study included more than 1000 patients undergoing primary ACL-reconstruction over a period of 4 years. Group 1 received intra-operative iv-antibiotics without pre-soaking of the graft. Group 2 received iv-antibiotics and additionally the graft was bathed in a vancomycin solution of 5 mg/mL. Results: In group 1, a total of 2,3% of the patients suffered a post-operative joint infection. In contrast, there were no post-operative infections in the second group (0%). Statistical analysis revealed a significantly reduced post-operative infection rate when bathing the autograft in vancomycin. Conclusion: Pre-soaking of hamstrings grafts with vancomycin combined with classical iv antibiotic prophylaxis reduced the rate of post-operative infection when compared to iv-antibiotics alone. This technique should be utilized to reduce the overall incidence of knee infections following ACL reconstruction.
[Clinical verification of vancomycin population pharmacokinetics in patients with augmented renal clearance].

OBJECTIVE To evaluate the predictive value and to verify the clinical effect of JPKD-vancomycin for the trough concentration of vancomycin in patients with augmented renal clearance (ARC), and to provide a reference for clinical individualized drug therapy. METHODS A retrospective analysis was conducted. The clinical data of 48 adult patients with ARC using vancomycin and monitoring steady-state trough concentration of vancomycin admitted to Suzhou Hospital Affiliated to Nanjing Medical University from July 2013 to July 2017 were collected. A combination of classical Vancomycin Calculator software and JPKD-vancomycin software was used. Based on the individual conditions of patients [gender, age, height, weight, serum creatinine (SCr), disease status], Vancomycin Calculator software was used to obtain the recommended regimen and its steady-state trough concentration, and then JPKD-vancomycin software was used to predict the steady-state trough concentration of initial regimen. If the regimen was adjusted during the treatment, JPKD-vancomycin software was used to predict the steady-state trough concentration of the adjusted regimen. The measured values of steady-state trough concentration were recorded. The weight deviation between predicted concentration and measured concentration (WRES) was calculated. WRES < 30% was considered as good prediction, and the predictive value of JPKD-vancomycin software was evaluated for vancomycin trough concentration. RESULTS Forty-eight patients with ARC were enrolled, of whom 24 patients had adjusted the dosing regimen during the treatment. The initial concentration of blood samples was 48, after adjusting the dosage regimen, 24 blood samples were collected. The initial and adjusted daily dose of vancomycin was (2 000±500) mg/d and (2 500±600) mg/d, respectively, and the initial trough concentrations and adjusted trough concentrations was (8.4±7.3) mg/L and (9.1±4.3) mg/L, respectively. Only 14.6% and 25.0% of initial and adjusted trough concentrations reached the target range (10-20 mg/L) without significant difference (P > 0.05). The WRES value of adjusted trough concentrations predicted by JPKD-vancomycin software was significantly lower than that of initial regimen [10.6% (3.0%, 16.4%) vs. 14.3% (10.5%, 38.2%), P < 0.05], and the percentage of WRES < 30% also tended to increase [95.8% (23/24) vs. 70.8% (34/48), P < 0.05]. The well predictive rate of JPKD-vancomycin software for vancomycin trough concentration was 79.2% (57/72), but there were 15 patients with WRES > 30%. CONCLUSIONS JPKD-vancomycin software has good predictive value for the vancomycin trough concentration of ARC patients, especially for the trough concentration after adjusting the treatment regimen. JPKD-vancomycin can provide a reference for the design of clinical individualized application of vancomycin.
Optimal discretization for geographical detectors-based risk assessment

The geographical detectors model is a new spatial analysis method for the assessment of health risks. It is adapted to discrete risk factors. Meanwhile, the geographical detectors model also effectively analyzes the continuous risk factors by discretizing the continuous data into discrete data. The biggest difficulty is in deciding how to discretize continuous risk factors using the most appropriate discretization method. In this paper, we will discuss the selection of an optimal discretization method for geographical detectors-based risk assessment, and exemplify the process using neural tube defects (NTD) from the Heshun County, Shanxi Province, China.
An SLA Corpus Annotated with Pedagogically Relevant Grammatical Structures

The evaluation of a language learner’s proﬁciency in second language is a task that normally involves comparing the learner’s production with a learning framework of the target language. One of the most well known frameworks is the Common European Framework for Languages (CEFR), which addresses language learning in general and is broadly used in the European Union, while serving as reference in countries outside the EU as well. In this study, we automatically annotated a corpus of texts produced by language learners with pedagogically relevant grammatical structures and observed how these structures are being employed by learners from different proﬁciency levels. We analyzed the use of structures both in terms of evolution along the levels and in terms of level in which the structures are used the most. The annotated resource, SGATe, presents a rich source of information for teachers that wish to compare the production of their students with those of already certiﬁed language learners.
Design of a Reversible Ripple Carry Adder for Excess-3 Code

One of the main characteristic in VLSI circuits is power dissipation. Due to the information loss, conventional logic circuits result in energy dissipation. Reversible circuits because they do not lose information, have zero internal power dissipation. This paper proposes a reversible 4-bit parallel adder for Excess-3 code. Excess-3 is an unweighted and self-complementing code. Excess-3 coding over BCD coding has various advantages. The primary superiority is that a decimal number can be nines' complemented (for subtraction) as facilely as a binary number can be ones' complemented by inverting all bits. The proposed Excess-3 adder in the number of reversible gates and garbage outputs, allowing high-speed and low-power reversible circuits, covers all favorable characteristics of reversible circuits. [Abdolzadeh V, Lotfivand N, Haghipour S. Design of a Reversible Ripple Carry Adder for Excess-3 Code. Life Sci J 2012;9(3):846-849]. (ISSN: 1097-8135). http://www.lifesciencesite. com. 119
Safety, tolerability and immunogenicity of the ExPEC4V (JNJ-63871860) vaccine for prevention of invasive extraintestinal pathogenic Escherichia coli disease: A phase 1, randomized, double-blind, placebo-controlled study in healthy Japanese participants

ABSTRACT This Phase 1, randomized, double-blind, placebo-controlled study was conducted to evaluate the safety, tolerability and immunogenicity of different doses of ExPEC4V conjugate vaccine (4-16µg Polysaccharide [PS]/serotype) in healthy Japanese participants, stratified into younger (≥20 to <50 years) or older age groups (≥50 years). Within each age group, participants were randomized to a single vaccination with 1 of 3 dose levels of ExPEC4V (4, 8 and 16 µg PS/serotype) or placebo. Safety and tolerability were the primary objectives; immunogenicity was secondary. Of the 48 participants, 47 (98%) completed; one (2%) in the placebo group discontinued. A total of 48% participants had ≥1 AE (younger group: n = 13 [54%]; older group: n = 10 [41.7%]). Solicited and unsolicited AEs were reported in 44% and 8% participants, respectively in the combined ExPEC4V groups. Pain/tenderness (n = 11 [31%]) and redness (n = 9 [25%]) were the most frequently reported solicited local AEs, whereas fatigue (n = 4 [11%]), headache (n = 4 [11%]), muscle pain (n = 2 [6%]), and malaise (n = 5 [14%]) were the most common solicited systemic AEs in the combined ExPEC4V group. No serious AEs, deaths, or discontinuation due to AEs were reported. All doses were immunogenic with an increase in IgG (ELISA) geometric mean titers of at least 5-fold from baseline to Days 15 and 30 for all serotypes. Of participants vaccinated with ExPEC4V, 75% - 100% demonstrated an ELISA titer increase of ≥2-fold. Strong correlation observed between ELISA and OPK. ExPEC4V was well tolerated and elicited an immunogenic response at all dose levels (up to 16 µg PS/serotype) in healthy Japanese participants.
Visual substitution system for room labels identification based on text detection and recognition

Vision is an essential human sense which is playing the most important role in human perception about surrounding environment. However such information is generally inaccessible for blind people. In order to enable these persons to overcome such incapability, we propose a system for identifying the neighbouring scene. In fact, the environment is labelled as a first step and then we present a personalised and adaptive method for labels detection and recognition. The automatic analysis involves the detection of personalised markers employed to extract the region of interest followed by the perspectives rectification based on homography estimation. We use the stroke width transform (SWT) to extract the text from the detected label and crop it into words and letters. The extracted text is identified using images correlation. Finally, as a substitution for visual modality, a vocal transformation of the recognised text is performed.