Miracle-dz/UniFAR-FTUs huggingface dataset:
Patient Relationship Management : Patient Care with CRM Approach

In the business world, customer relationship management is utilized to hold customer reliability so as to expand income. Healthcare associations can fabricate a similar sort of relationship with patients, and it can likewise offer progressively unmistakable advantages. The principal advantage is by utilizing a similar hospital a patient's treatment history ought to be moderately outstanding by the association. Intermittently, extraordinary hospitals utilize distinctive patient data frameworks which are not constantly perfect with one another. On the off chance that a patient continues changing the hospital, his or her medical record can be dissipated around different destinations. In a perfect world, if the patient is treated by a similar doctor in each visit, that doctor will get progressively comfortable with the patient, which could enhance treatment. The most unmistakable advantage, be that as it may, is time. In the event that the patient goes to a similar doctor inevitably, there is no requirement for long registration toward the start of each visit. In spite of the fact that a developing collection of proof backings the utilization of cell phone short message service (SMS) for increasing physical movement, sustenance, and smoking suspension, past investigations were constrained by an attention on center to upper pay populaces, and have not focused on transcendently country networks outside the healthcare conveyance framework. Hospital websites are considered as a fitting framework for trading data and building up correspondence between patients, hospitals, and medical staff. Website character, website contact intelligence, shopping accommodation, just as consideration and service are the variables to the extent the patient relationship management is concerned. In healthcare situations, patients are considered as the primary customers; in this way, the term Patient Relationship Management (PRM) is utilized in these unique situations. PRM permits healthcare focuses to have a superior understanding into the requirements of patients while giving them better consideration. Thusly, PRM gives a chance to utilize information and data to comprehend customers and to make an incentive with them. The requirement for PRM developed when associations comprehended that it was less exorbitant to keep their present customers, while pulling in another customer would be more-expensive for an association than keeping their present customers.
Differential excitability and voltage‐dependent Ca2+ signalling in two types of medial entorhinal cortex layer V neurons

The entorhinal cortex (EC) is a key structure in memory formation, relaying sensory information to the hippocampal formation and processed information to the neocortex. EC neurons in the deep layers modulate the transfer of sensory information by the superficial layers and the dentate gyrus, and form the output to the neocortex. Here we characterize two types of EC layer V neurons by their fluorescence morphology, electrophysiology and intracellular Ca2+ signalling using intracellular recording and Ca2+ imaging. Pyramidal neurons show, in response to depolarizing current pulses, regular firing with strong adaptation and a fast and medium afterhyperpolarization (AHP) which are separated by a depolarizing notch and, with hyperpolarizing current injection, a transient sag. Multipolar cells respond to depolarization with delayed firing with very weak adaptation and have no depolarizing notch between fast and medium AHP and no sag with hyperpolarization. The delayed firing was blocked by 30 µm 4‐aminopyridine, indicating mediation by the D‐type potassium current. Subthreshold depolarization evoked membrane potential oscillations of 2–5 Hz in both cell types and an increase in [Ca2+]i of 37 nm in pyramidal and 59 nm in multipolar neurons. Repetitive firing at 10 Hz for 30 s increased [Ca2+]i in pyramidal and multipolar neurons by 194 and 295 nm, respectively. Differential temporal firing and Ca2+ signalling suggest specific information processing and synaptic memory storage possibilities in these two layer V cell types of the EC.
Multi-robot cooperation for human-robot communication

This paper illustrates how robots can effectively cooperate to facilitate communication with people. We expect that communication robots will play an important role in our daily life. Although these robots can communicate with each other by radio, infrared, or other invisible means, our results show that it is important to human understanding that they are able to communicate with each other by voice and gestures as well. This lets humans know that the robots can talk with them and among themselves. Thus, humans come to regard the robots as appropriate targets for natural communication.
Data-driven knowledge extraction for the food domain

In this paper, we examine methods to automatically extract domain-specific knowledge from the food domain from unlabeled natural language text. We employ different extraction methods ranging from surface patterns to co-occurrence measures applied on different parts of a document. We show that the effectiveness of a particular method depends very much on the relation type considered and that there is no single method that works equally well for every relation type. We also examine a combination of extraction methods and also consider relationships between different relation types. The extraction methods are applied both on a domain-specific corpus and the domain-independent factual knowledge base Wikipedia. Moreover, we examine an open-domain lexical ontology for suitability.
Explicit Haar-Schauder multiwavelet filters and algorithms. Part II: Relative entropy-based estimation for optimal modeling of biomedical signals

Biomedical signal/image processing and analysis are always fascinating tasks in scientific researches, both theoretical and practical. One of the powerful tools in such topics is wavelet theory which has been proved to be challenging since its discovery. One of the best measures of the optimality of reconstruction of signals/images is the well-known Shannon’s entropy. In wavelet theory, this is very well known and researchers are familiar with it. In the present work, a step forward is proposed based on more general wavelet tools. New approach is proposed for the reconstruction of signals/images provided with multiwavelets Shannon-type entropy to evaluate the order/disorder of the reconstructed signals/images. Efficiency and accuracy of the approach is confirmed by a simulation study on several models such as ECG, EEG and DNA/Proteins’ signals.
Learning-Based Driving Events Recognition and Its Application to Digital Roads

Automatic recognition of driving events, e.g., approaching roundabouts, is important both for the truck design process based on simulated road data and for advanced driver assistance systems. However, the problem faced is extremely challenging as only in-vehicle driving data must be used, whereas the number of driving events is usually quite large. In this paper, we propose a learning-based driving events classification method, which is trained and tested with a real driving events database. The proposed method includes definition of driving events relevant to our final application, selection of discriminating features, and classification, using two machine-learning techniques, namely, decision trees and linear logistic regression. We then introduce the digital road concept. This consists of simulated road data used in the truck design process to quantify the behavior of a truck, particularly in terms of fuel consumption. While a digital road typically contains far less driving information, we show that we can still apply the proposed driving events recognition models learnt on real driving data and pave the way for a more realistic assessment of truck characteristics via simulation tools.
Analysis of DVB-T Reception Results Using a Slight Steering Technique of the Antenna Radiation Diagram

The aim of the present study is to present a new technique in order to improve the receiving Terrestrial Digital Video Broadcasting (DVB-T) signal in portable reception, using a slight steering of the antenna radiation diagram. It seems that the proposed technique moderates the reception quality differences at different points of the coverage area, increasing the total number of the DVB-T users.
Eyes are the window to the soul

Although the origin cannot be confirmed, the saying ‘the eyes are the window to the soul’ is thought to trace back to the Book of Matthew in the Bible or to Cicero (106–143 BC). Supporting that saying, the article by Crewe et al. in this issue of Clinical and Experimental Ophthalmology reveals a strong association between depression and quality of life in people with severe vision impairment. This study and a growing body of research on the impact of vision impairment on quality of life and disability-adjusted life years reveal the importance of vision to quality of life. Depression is known to have affects on systemic health and is associated with increased mortality. The article by Crewe et al. demonstrates effect modification (to use an epidemiological term) in the relationship of depression and quality of life in people with severe vision impairment. It is worth considering these components separately. Depression rates vary greatly between countries, in part due to differences in assessment and definition, and in part due to cultural and perhaps genetic differences. A review of population-based depression rates reveals a greater than 10-fold variation, from 3.6% in China to 20.5% in Australia. In the USA, depression rates fell from 2004 to 2008, but the rates are higher in younger cohorts. Rates and causes of vision impairment also vary globally, in part due to measurement differences and in part due to access to health care services and differing environmental causes of vision impairment. Population-based studies show vision impairment ranging from 1.98% in the USA to 11.8% in Rotterdam. Vision impairment is expected to increase globally with increasing life expectancy and decreasing fertility rates because the major causes of vision impairment are age-related. How do rates of depression and vision impairment compare globally? A simple correlation of populationbased rates of vision impairment versus population-based rates of depression in six countries reveals a strong, although statistically insignificant correlation due to the small number of data points (Fig. 1, correlation = 0.65, P = 0.16, SPSS© version 15.0, Chicago, IL, USA). Although these data are subject to the ecological fallacy where individual-level associations cannot necessarily be inferred from group-level data as demonstrated in Figure 1, they do suggest an association between vision impairment and depression at the population level. The article by Crewe et al. clearly demonstrates the strong association between depression and quality of life for people with severe vision impairment. Perhaps eye care professionals should routinely screen and refer for depression and mental health professionals should screen and refer their patients for vision disorders that might be treatable. By attending to depression in people with vision impairment, it may be possible to improve their quality of life. This has profound clinical and public health implications.
Ror2 is required for midgut elongation during mouse development

The receptor tyrosine kinase Ror2 acts as a receptor for Wnt5a to mediate noncanonical Wnt signaling, and it plays essential roles in morphogenesis. Ror2−/− embryos exhibit phenotypes similar to, albeit generally milder than, those of Wnt5a−/− embryos. During mouse embryogenesis, Ror2 is expressed in various organs and regions, although little is known about its expression pattern and roles in the developing gut, while Wnt5a is expressed in the developing gut, where its absence causes abnormal phenotypes. Here, we demonstrated that Ror2 was strongly and differentially expressed in the rostral and middle midgut endoderm from embryonic day (E) 10.5 through embryonic day (E) 12.5. At E11.5, Ror2−/− embryos exhibited a shorter middle midgut with a larger diameter and more accumulation of epithelial cells in the middle midgut than control embryos, while the total cell numbers remained unaltered. These findings suggest that Ror2 plays important roles in midgut elongation by means of an epithelial convergent extension mechanism. Developmental Dynamics 239:941–953, 2010. © 2010 Wiley‐Liss, Inc.
Dnn-based Spectral Enhancement for Neural Waveform Generators with Low-bit Quantization

This paper presents a spectral enhancement method to improve the quality of speech reconstructed by neural waveform generators with low-bit quantization. At training stage, this method builds a multiple-target DNN, which predicts log amplitude spectra of natural high-bit waveforms together with the amplitude ratios between natural and distorted spectra. Log amplitude spectra of the waveforms reconstructed by low-bit neural waveform generators are adopted as model input. At generation stage, the enhanced amplitude spectra are obtained by an ensemble decoding strategy, and are further combined with the phase spectra of low-bit waveforms to produce the final waveforms by inverse STFT. In our experiments on WaveRNN vocoders, an 8-bit WaveRNN with spectral enhancement outperforms a 16-bit counterpart with the same model complexity in terms of the quality of reconstructed waveforms. Besides, the proposed spectral enhancement method can also help an 8-bit WaveRNN with reduced model complexity to achieve similar subjective performance with a conventional 16-bit WaveRNN.
Educating Oncology Nurses About the Emotional Impact of Cancer Diagnosis

Educating Oncology Nurses About the Emotional Impact of Cancer Diagnosis by Jonnell Ortiz-Zayas MSN, Metropolitan University, 2015 BSN, Interamerican University, 2011 Project Submitted in Partial Fulfillment of the Requirements for the Degree of Doctor of Nursing Practice Walden University November 2018 Abstract Anxiety and depression are common mood disorders in cancer patients, regardless of mental state prior to diagnosis. A gap in the education of oncology nurses in an eastern Caribbean island was discovered regarding their ability to identify anxiety and depression symptoms and to help patients who suffered from these disorders. The purpose of this project was to improve oncology nurses’ assessment skills by reviewing appropriate useAnxiety and depression are common mood disorders in cancer patients, regardless of mental state prior to diagnosis. A gap in the education of oncology nurses in an eastern Caribbean island was discovered regarding their ability to identify anxiety and depression symptoms and to help patients who suffered from these disorders. The purpose of this project was to improve oncology nurses’ assessment skills by reviewing appropriate use of the Hospital Anxiety and Depression Scale (HADS) tool and familiarizing nurses with resources to help patients who score high on the HADS. The Levine conservation model was the theoretical framework for this project. The research question addressed whether a staff education module regarding the use of the HADS tool would improve staff knowledge about screening cancer patients for mood disorders in a clinic setting. This project involved a staff education module with a pretest/posttest assessment and evaluation of the responses and levels of improvement. A total of 10 oncology nurses with varying academic degrees and years of experience participated in the project. The pretest showed that many had inadequate knowledge of the HADS tool. Based on posteducation assessment scores, all participants understood how to use the tool to screen for mood disorders. The implication of this study for positive social change is that oncology nurses will be able to use a screening tool to identify undiagnosed anxiety and depression symptoms in cancer patients and provide patients with appropriate resources. Educating Oncology Nurses About the Emotional Impact of Cancer Diagnosis by Jonnell Ortiz-Zayas MSN, Metropolitan University, 2015 BSN, Interamerican University, 2011 Project Submitted in Partial Fulfillment of the Requirements for the Degree of Doctor of Nursing Practice Walden University November 2018 Dedication I dedicate this DNP project to my whole family, especially to my mother, Gladys, and to the love of my life, Jorge, because without their support and unconditional love, this achievement would not have been possible. I also dedicate this project to Dr. Evelyn Pedreira (RIP) who always believed in me and gave me all her support and encouragement when I started this adventure. Wherever you are, I know you must be
Cdk1 Targets Srs2 to Complete Synthesis-Dependent Strand Annealing and to Promote Recombinational Repair

Cdk1 kinase phosphorylates budding yeast Srs2, a member of UvrD protein family, displays both DNA translocation and DNA unwinding activities in vitro. Srs2 prevents homologous recombination by dismantling Rad51 filaments and is also required for double-strand break (DSB) repair. Here we examine the biological significance of Cdk1-dependent phosphorylation of Srs2, using mutants that constitutively express the phosphorylated or unphosphorylated protein isoforms. We found that Cdk1 targets Srs2 to repair DSB and, in particular, to complete synthesis-dependent strand annealing, likely controlling the disassembly of a D-loop intermediate. Cdk1-dependent phosphorylation controls turnover of Srs2 at the invading strand; and, in absence of this modification, the turnover of Rad51 is not affected. Further analysis of the recombination phenotypes of the srs2 phospho-mutants showed that Srs2 phosphorylation is not required for the removal of toxic Rad51 nucleofilaments, although it is essential for cell survival, when DNA breaks are channeled into homologous recombinational repair. Cdk1-targeted Srs2 displays a PCNA–independent role and appears to have an attenuated ability to inhibit recombination. Finally, the recombination defects of unphosphorylatable Srs2 are primarily due to unscheduled accumulation of the Srs2 protein in a sumoylated form. Thus, the Srs2 anti-recombination function in removing toxic Rad51 filaments is genetically separable from its role in promoting recombinational repair, which depends exclusively on Cdk1-dependent phosphorylation. We suggest that Cdk1 kinase counteracts unscheduled sumoylation of Srs2 and targets Srs2 to dismantle specific DNA structures, such as the D-loops, in a helicase-dependent manner during homologous recombinational repair.
R Neighborhood and Family Effects on Children ’ s Health in Los Angeles Narayan

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Explorer Systematic review and meta-analysis of the diagnostic accuracy of ultrasonography for deep vein thrombosis

Background: Ultrasound (US) has largely replaced contrast venography as the definitive diagnostic test for deep vein thrombosis (DVT). We aimed to derive a definitive estimate of the diagnostic accuracy of US for clinically suspected DVT and identify study-level factors that might predict accuracy. Methods: We undertook a systematic review, meta-analysis and meta-regression of diagnostic cohort studies that compared US to contrast venography in patients with suspected DVT. We searched Medline, EMBASE, CINAHL, Web of Science, Cochrane Database of Systematic Reviews, Cochrane Controlled Trials Register, Database of Reviews of Effectiveness, the ACP Journal Club, and citation lists (1966 to April 2004). Random effects meta-analysis was used to derive pooled estimates of sensitivity and specificity. Random effects meta-regression was used to identify study-level covariates that predicted diagnostic performance. Results: We identified 100 cohorts comparing US to venography in patients with suspected DVT. Overall sensitivity for proximal DVT (95% confidence interval) was 94.2% (93.2 to 95.0), for distal DVT was 63.5% (59.8 to 67.0), and specificity was 93.8% (93.1 to 94.4). Duplex US had pooled sensitivity of 96.5% (95.1 to 97.6) for proximal DVT, 71.2% (64.6 to 77.2) for distal DVT and specificity of 94.0% (92.8 to 95.1). Triplex US had pooled sensitivity of 96.4% (94.4 to 97.1%) for proximal DVT, 75.2% (67.7 to 81.6) for distal DVT and specificity of 94.3% (92.5 to 95.8). Compression US alone had pooled sensitivity of 93.8 % (92.0 to 95.3%) for proximal DVT, 56.8% (49.0 to 66.4) for distal DVT and specificity of 97.8% (97.0 to 98.4). Sensitivity was higher in more recently published studies and in cohorts with higher prevalence of DVT and more proximal DVT, and was lower in cohorts that reported interpretation by a radiologist. Specificity was higher in cohorts that excluded patients with previous DVT. No studies were identified that compared repeat US to venography in all patients. Repeat US appears to have a positive yield of 1.3%, with 89% of these being confirmed by venography. Conclusion: Combined colour-doppler US techniques have optimal sensitivity, while compression US has optimal specificity for DVT. However, all estimates are subject to substantial unexplained heterogeneity. The role of repeat scanning is very uncertain and based upon limited data. Published: 03 October 2005 BMC Medical Imaging 2005, 5:6 doi:10.1186/1471-2342-5-6 Received: 23 May 2005 Accepted: 03 October 2005 This article is available from: http://www.biomedcentral. com/1471-2342/5/6 © 2005 Goodacre et al; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. BMC Medical Imaging 2005, 5:6 http://www.biomedcentral. com/1471-2342/5/6
Triamterene inhibits the delayed rectifier potassium current (IK) in guinea pig ventricular myocytes.

In humans, proarrhythmia during therapy with action potential-prolonging drugs can be associated with hypokalemia often provoked by concomitant administration of diuretic agents. Consequently, therapy with class III antiarrhythmics and K(+)-sparing diuretics, such as triamterene, may be indicated. Triamterene, along with its K(+)-sparing properties, exhibits other pharmacological effects. In the heart, it can increase action potential duration (guinea pig atria and papillary muscles), protect against reperfusion-induced arrhythmias (rat), and increase the QT interval (humans). Therefore, studies were undertaken to assess effects of triamterene on cardiac K+ repolarizing currents. Guinea pig ventricular myocytes were superfused at 30 degrees C with Cd(2+)-containing solution to block Isi and held at -40 mV to inactivate INa. Currents were measured in the whole-cell configuration of the patch-clamp technique. The delayed rectifier outward current (IK) was elicited by short (250-millisecond) and long (5000-millisecond) depolarizing pulses, and time-independent currents were assessed by a rapid ramp test protocol. After high-voltage long pulses (+50 mV; 5000 milliseconds), tail current amplitude of the slow component of IK (IKs) was decreased 36 +/- 6% (n = 6) and 51 +/- 8% (n = 6) by triamterene 10(-5) and 10(-4) mol/L, respectively. After low-voltage short pulses (-20 mV; 250 milliseconds), tail current amplitude corresponding essentially to the rapid component of IK (IKr) was decreased only 14 +/- 11% (n = 9) and 19 +/- 10% (n = 10) by triamterene 10(-5) and 10(-4) mol/L, respectively. (ABSTRACT TRUNCATED AT 250 WORDS)