Miracle-dz/UniFAR-FTUs huggingface dataset:
Measuring the Implications of Sales and Consumer Stockpiling Behavior

Temporary price reductions (sales) are common for many goods and naturally result in large increases in the quantity sold. In previous work we found that the data support the hypothesis that these increases are, at least partly, due to stockpiling. In this paper we quantify the extent of stockpiling and assess its economic implications. We construct and structurally estimate a dynamic model of consumer choice using two years of scanner data on the purchasing behavior of a panel of households. The results suggest that static demand estimates, which neglect dynamics, may: (i) overestimate own price elasticities by 30 percent; (ii) underestimate cross-price elasticities to other products by up to a factor of 4; and (iii) overestimate the substitution to the no purchase, or outside option, by up to 150 percent.
Multiple model modeling and predictive control of the pH neutralization process

induce the need for sophisticated control systems. Model predictive control represents such control method which makes explicit use of a model of the process to obtain the control signal. The performance of control algorithm depends on the quality of the derived model. A possible approach is to decompose the nonlinear dynamics into multiple linear models and switch or interpolate them based on the current operating conditions. Multiple models structure for modeling and control allow the transfer of many methods from the linear control theory to the nonlinear systems. The process operations are partitioned into several operating regions and within each region, a local linear model is developed to approximate the process. To save on computational load, a linear model is obtained by interpolating these linear models at each sample point and then obtained model is used in a Generalized Predictive Control (GPC) framework. The manipulated variable adjustments are computed through optimization at each sampling interval. The proposed identification and control method is illustrated by the simulation study on a nonlinear process.
A Novel Text Categorization Approach based on K- means and Support Vector Machine

Continuous expansion of digital libraries and online news, the huge amount of text documents is existing on the web. Consequently the need is to organize them. Text Categorization is an active analysis field can be used for organizing text document. Text categorization is the process of assigning documents with predefined categories that are associated with their contented. CAWP algorithm is designed for Text Categorization. But this algorithm does not present the best results for large datasets. K-means Clustering with Support Vector Machine approach is used to enhance the results. K-means group the data into a number of clusters follow which it uses as training samples for Support Vector Machine in each cluster to divide the new sample data efficiently. The experiment performed on 20Newsgroups dataset, K-means with SVM provides better results than CAWP algorithm in terms of F-measure.
The interface between metabolic and stress signalling.

BACKGROUND It is becoming increasingly clear that stress and metabolic signalling networks interact and that this interaction is important in plant responses to herbivory, pathogen attack, drought, cold, heat and osmotic stresses including salinity. At the interface between these two major signalling systems are the hormone abscisic acid (ABA) and signalling factors including protein kinases and transcription factors. SCOPE This briefing reviews links between ABA, stress and sugar signalling, focusing on the roles of sucrose non-fermenting-1-related protein kinases (SnRKs), SnRK1-activating protein kinases (SnAKs), calcium-dependent protein kinases (CDPKs) and ABA response element binding proteins (AREBPs, which are transcription factors). Links between stress and nitrogen / amino acid signalling are also described, including the roles of a protein kinase called general control non-derepressible (GCN)-2 in regulating protein synthesis through phosphorylation of the alpha-subunit of translation initiation factor-2 (eIF2alpha) in response not only to decreases in amino acid levels but also to a range of stresses. Evidence of a link between sugar and amino acid signalling is explored, with nitrate reductase being a target for regulation by both SnRK1 and GCN2 through different mechanisms; possible links between SnRK1 and GCN2 via a pathway including the protein kinase target of rapamycin (TOR)-1 are described. The significance of these interactions to the concept of signalling networks as opposed to simple cascades and pathways, and the importance of the subject in the context of the predicted increase in severity and range of stresses that plants will have to withstand as a result of global climate change are discussed.
RNase MRP Cleaves Pre-tRNASer-Met in the tRNA Maturation Pathway

Ribonuclease mitochondrial RNA processing (RNase MRP) is a multifunctional ribonucleoprotein (RNP) complex that is involved in the maturation of various types of RNA including ribosomal RNA. RNase MRP consists of a potential catalytic RNA and several protein components, all of which are required for cell viability. We show here that the temperature-sensitive mutant of rmp1, the gene for a unique protein component of RNase MRP, accumulates the dimeric tRNA precursor, pre-tRNASer-Met. To examine whether RNase MRP mediates tRNA maturation, we purified the RNase MRP holoenzyme from the fission yeast Schizosaccharomyces pombe and found that the enzyme directly and selectively cleaves pre-tRNASer-Met, suggesting that RNase MRP participates in the maturation of specific tRNA in vivo. In addition, mass spectrometry–based ribonucleoproteomic analysis demonstrated that this RNase MRP consists of one RNA molecule and 11 protein components, including a previously unknown component Rpl701. Notably, limited nucleolysis of RNase MRP generated an active catalytic core consisting of partial mrp1 RNA fragments, which constitute “Domain 1” in the secondary structure of RNase MRP, and 8 proteins. Thus, the present study provides new insight into the structure and function of RNase MRP.
Simultaneous Adaptive Path Planning System for Planetary Rover

In this paper, we propose a path planning system named SAP (Simultaneous Adaptive Path planning) which can make a plan adapt to kinematic and dynamic constraints, and dynamically changing environment simultaneously. SAP has three key issues: condition layers, a dynamic space, and a search tree. Each condition layer involves a factor which influences running of the robot such as coefficient of friction and elevation of the field. Dynamic space is an area in velocity domain where the robot could reach in the next time step. The limitation (means outer shape) of the dynamic space is defined as a function of all conditions and a robot model, velocities that can be achieved within a short time interval. Search tree that consider the dynamic space expands like tree to search a path from start to goal. By these mechanisms, SAP can generate a path that robot can achieve in real environment.
Anti-Angiogenic Effects of a Mutant Endostatin: A New Prospect for Treating Retinal and Choroidal Neovascularization

Purpose Pathological fundus angiogenesis is a major cause of vision loss in retina diseases. Endostatin, a C-terminal fragment of collagen XVIII, is an endogenous anti-angiogenic protein. The present study aimed to investigate the in vitro and in vivo anti-angiogenic properties of two proteins: an N-terminal H1D/H3D mutant endostatin (M-ES) and a polyethylene glycol propionaldehyde (PEG) covalent M-ES (PEG-M-ES). Methods M-ES and PEG-M-ES properties were characterized in vitro using a zinc ion binding assay and a stability test. Activity assays, including migration, proliferation, and tube formation assays, were performed with human retinal microvascular endothelial cells (HRMECs) and human umbilical vein endothelial cells (HUVECs). Mouse oxygen-induced retinopathy (OIR) and choroidal neovascularization (CNV) models were used to evaluate in vivo anti-angiogenic effects. In addition, a rabbit model was used to study the retinal pharmacokinetic profile following an intravitreal injection. Results The results indicated that the H1D/H3D mutations of endostatin reduced the zinc binding capacity of M-ES and facilitated PEG covalent binding. PEG-M-ES was more stable and persisted longer in the retina compared with M-ES. The in vitro studies demonstrated that M-ES and PEG-M-ES inhibited HRMEC and HUVEC proliferation, migration, and tube formation more efficiently than ES. In vivo, a single intravitreal injection of M-ES and PEG-M-ES significantly decreased neovascularization in both the OIR and CNV animal models. Conclusion The present study demonstrated for the first time that PEG-M-ES exhibits a long-term inhibitory effect on neovascularization in vitro and in vivo. These data suggest that PEG-M-ES may represent an innovative therapeutic strategy to prevent fundus neovascularization.
Transfection of human macrophages by lipoplexes via the combined use of transferrin and pH‐sensitive peptides

The crucial function of macrophages in a variety of biological processes and pathologies render these cells important targets for gene therapeutic interventions. Commonly used synthetic gene delivery vectors have not been successful in transfecting these non‐dividing cells. A combination strategy involving cationic liposomes to condense and carry DNA, transferrin to facilitate cellular uptake, and the pH‐sensitive peptide GALA to promote endosome destabilization, resulted in significant expression of a luciferase gene. Transfection of macrophages was dependent on the degree of differentiation of the cells. The quaternary complexes of cationic liposomes, DNA, transferrin, and GALA exhibited a net negative charge, which may obviate a limitation of cationic synthetic vectors in vivo. The lack of cytotoxicity and the expected lack of immunogenicity of these complexes may render them useful for gene delivery to macrophages in vivo. J. Leukoc. Biol. 65: 270–279; 1999.
Does the Endowment Effect Influence Outcomes in Takings Cases? Evidence from Some Important Cases and Implications for Planning Ethics and Practice

states that private property shall not ―be taken for public use, without just compensation. ‖ Despite the apparent simplicity of the amendment, the issue remains controversial. For instance, the United States Supreme Court (USSC) has noted that it cannot establish a ―set formula‖ for determining when a taking has occurred (Penn Central Transportation Co. v. New York City, 438 U.S. 104, 1978). Controversies of interest to planners usually center on whether a regulation goes ―too far‖ and what constitutes ―public use. ‖ 1 The literature on takings falls into two categories: legal and economic. Legal analyses include landmark pieces by Michelman (1967), who emphasizes fairness, and Epstein (1985), who takes a libertarian perspective. Economic analyses range from rational expectations theory 2 These approaches share the underlying assumptions that landowners, judges, and planners, are rational decision makers and that market efficiency is, or should be, a critical consideration in decisions. 3 However, the assumption of perfect rationality has come under attack from a growing body of evidence in behavioral psychology. In response to the limitations of the rational model, this literature attempts to explain the law from a behavioral perspective (e. component of this literature is the endowment effect. The endowment effect—also known as the status-quo bias—is the tendency of people to hold on to property and rights that they have, implicitly placing more value on these properties 2 and rights than if they never possessed them (Thaler 1980). The endowment effect has been found to apply in many contexts, from a reluctance to trade possessions (Kahneman, Knetsch, and Thaler 1990; 1991) to a reluctance to change medical plans (Samuelson and Zeckhauser 1988). The effect is evident in numerous studies that show that people are willing to accept (WTA) more for property they own than they are willing to pay (WTP) for the same property if they had not owned it (see Horowitz and McConnell 2002 for a summary of some of these studies). The endowment effect suggests that allocations of property by independent parties are likely to favor those already holding endowments (Korobkin 2003), which include ownership, momentum toward ownership, or perceptions of ownership. Against this backdrop, I address my first question: Can the endowment effect provide insight into courts' decisions in takings cases? I selected cases for review from a list of important takings cases maintained by the Community Rights Counsel (CRC), a nonprofit, public interest law firm based in Washington, …
Plasmonic Light Trapping Transforming Thin-Film Photovoltaics

The photovoltaics (PV) market represents the fastest growing renewable energy technology, with a 35% annual growth rate, which is projected to be worth $150B by 2018. [1] The global cumulative installed PV capacity has exceeded 140 GW in 2013 and is generating 160 TWh/year of electricity, representing 0.85% of worldwide electricity demand. At the present growth rate, it is projected that over 20% of all electricity could be supplied by PV by 2050 [1].
Development of an algorithm to provide awareness in choosing study designs for inclusion in systematic reviews of healthcare interventions: a method study

Objectives To develop an algorithm that aims to provide guidance and awareness for choosing multiple study designs in systematic reviews of healthcare interventions. Design Method study: (1) To summarise the literature base on the topic. (2) To apply the integration of various study types in systematic reviews. (3) To devise decision points and outline a pragmatic decision tree. (4) To check the plausibility of the algorithm by backtracking its pathways in four systematic reviews. Results (1) The results of our systematic review of the published literature have already been published. (2) We recaptured the experience from our four previously conducted systematic reviews that required the integration of various study types. (3) We chose length of follow-up (long, short), frequency of events (rare, frequent) and types of outcome as decision points (death, disease, discomfort, disability, dissatisfaction) and aligned the study design labels according to the Cochrane Handbook. We also considered practical or ethical concerns, and the problem of unavailable high-quality evidence. While applying the algorithm, disease-specific circumstances and aims of interventions should be considered. (4) We confirmed the plausibility of the pathways of the algorithm. Conclusions We propose that the algorithm can assist to bring seminal features of a systematic review with multiple study designs to the attention of anyone who is planning to conduct a systematic review. It aims to increase awareness and we think that it may reduce the time burden on review authors and may contribute to the production of a higher quality review.
Beauty is attractive: Moduli trapping at enhanced symmetry points

We study quantum effects on moduli dynamics arising from the production of particles which are light at points of enhanced symmetry in moduli space. The resulting forces trap the moduli at these points. Moduli trapping occurs in time-dependent quantum field theory, as well as in systems of moving D-branes, where it leads the branes to combine into stacks. Trapping also occurs in the presence of gravity, though the range over which the moduli can roll is limited by Hubble friction. We observe that a scalar field trapped on a steep potential can induce a stage of acceleration of the universe, which we call trapped inflation. Moduli trapping ameliorates the cosmological moduli problem and may affect vacuum selection. In particular, rolling moduli are most powerfully attracted to the points of greatest symmetry. Given suitable assumptions about the dynamics of the very early universe, this effect might help to explain why among the plethora of possible vacuum states of string theory, we appear to live in one with a large number of (spontaneously broken) symmetries.
THE PERCEPTIONS AMONG INTERNATIONAL TOURISTS TOWARD ENVIRONMENT IMPACTS AT TANJUNG TUAN

The challenge to tourism that is presented by sustainable approach is how to preserve and conserve many natural attractions and today in tourism industry development will have an impacts on environmental. Environment, either physical, social and economics have a positive and negative impacts. The purpose of this study was to examined the perception among international students from University Gadjah Mada, Yogyakarta, Indonesia toward environmental impacts at Tanjung Tuan Melaka. For this purpose, qualitative method was used in order to get a perception toward environmental issues among international students from interviews activities. The results show that environmental issues at Tanjung Tuan is not serious and have a good perception among international students, just need to develop some facilities to faced many tourists.
New design of orthogonal filter banks using the Cayley transform

It is a challenging task to design orthogonal filter banks, especially multidimensional (MD) ones. In the one-dimensional (1D) two-channel finite impulse response (FIR) filter bank case, several design methods exist. Among them, designs based on spectral factorizations (by Smith and Barnwell) and designs based on lattice factorizations (by Vaidynanathan and Hoang) are the most effective and widely used. The 1D two-channel infinite impulse response (IIR) filter banks and associated wavelets were considered by Herley and Vetterli. All of these design methods are based on spectral factorization. Since in multiple dimensions, there is no factorization theorem, traditional 1D design methods fail to generalize. Tensor products can be used to construct MD orthogonal filter banks from 1D orthogonal filter banks, yielding separable filter banks. In contrast to separable filter banks, nonseparable filter banks are designed directly, and result in more freedom and better frequency selectivity. In the FIR case, Kovacevic and Vetterli designed specific two-dimensional and three-dimensional nonseparable FIR orthogonal filter banks. In the IIR case, there are few design results (if any) for MD orthogonal IIR filter banks. To design orthogonal filter banks, we must design paraunitary matrices, which leads to solving sets of nonlinear equations. The Cayley transform establishes a one-to-one mapping between paraunitary matrices and para-skew-Hermitian matrices. In contrast to nonlinear equations, the para-skew-Hermitian condition amounts to linear constraints on the matrix entries which are much easier to solve. We present the complete characterization of both paraunitary FIR matrices and paraunitary IIR matrices in the Cayley domain. We also propose efficient design methods for MD orthogonal filter banks and corresponding methods to impose the vanishing-moment condition.
Teaching Schizophrenia: 8-Minutes Video Based Lecture Versus 1-hour Traditional Lecture

Video-based teaching module is well known and practiced in some university courses but the effort to validate this type of education tool in medical and health education system is yet to be expanded and explored especially from pharmacy students’ perspective. Materials and method: forty pharmacy students evaluated their experience from attending a one-hour lecture and watching a short video-based lecture lasted for eight minutes both were about clinical presentation and diagnosis of schizophrenia. Result and discussion: 70% of the sample (n=28) preferred video- based lecturing. Advantages and disadvantages varied from faculty and students’ perspectives, but it saved time, was enjoyable and memorable. Conclusion: positive agreement of pharmacy students toward schizophrenia video-based lecture was assured and effort must be put on validating video-based lecture content.
Managing Knowledge in Human Resource Practices and Innovation Performance

This study examines the mediating role of knowledge management in the relationship between human resource practices and innovation performance. Employing a sample of 146 firms in Taiwan, we propose that human resource practices facilitate knowledge management and such knowledge management mediates the relationship between human resource practices and innovation performance. Our results indicate that human resource practices are positively related to knowledge management. Knowledge management is, in turn, positively related to innovation performance. Further, our results provide evidence that knowledge management plays a mediating role between human resource practices and innovation performance.
VLR: Cockroach millirobot with load decoupling structure

This paper presents the development of Very Large RoACH (VLR), which is a rapidly-prototyped folded cardboard cockroach-like robot for carrying relatively heavy loads. To increase load capacity, a vertically movable platform is designed, which can decouple an internal payload from loading the robot hips. Based on the previous VelociRoACH design, VLR is designed for greater load capacity, by 160% size scaling. After building a prototype, experiments are performed. The speed and traction force are measured to validate the performance of the proposed robot. Through these experiments, it was found that the speed of the robot increases by 2.2 times and the traction force increases by 1.4 times using the proposed mechanism compared to the design without load decoupling.
Limited survival of adult human testicular tissue as ectopic xenograft.

BACKGROUND Grafting of testicular tissue into immunodeficient mice has become an interesting and promising scientific tool for the generation of gametes and the study of testicular function. This technique might potentially be used to generate sperm from patients whose testes need to be removed or are destroyed due to therapeutic intervention or as a consequence of disease. Here we explore whether adult human testicular tissue from patients with different testicular pathologies survives as xenograft. METHODS AND RESULTS Testis tissue from adult patients with varying degrees of spermatogenesis was grafted into two strains of immunodeficient mice (severe combined immunodeficiency, Nu/Nu). Tissue with active spermatogenesis prior to grafting largely regressed. However, testicular tissue survival was better in cases where spermatogenesis was suppressed prior to grafting and occasionally spermatogonial stem cells survived. Cases with spermatogenic disruption were not corrected by the xenografting. CONCLUSION Superior survival of the germinal epithelium and spermatogonia when spermatogenesis was suppressed prior to grafting could provide a novel strategy for germline preservation in pre-pubertal cancer patients. This approach could also be valuable to study the early stages of human spermatogenesis.
Secret Image Sharing Scheme with Flexible Adjustment Shadow Images

Secret image sharing is a technique for protecting images from being grabbed or tampered with. It involves the partition of the secret image into many shadow images. Usually, the small shadow images are useful for fast transmission and storage. However, the smaller size of shadows means more data compressed with low quality images. In order to reconcile this contradiction, a new scheme which can flexibly adjust the relationship between the size of shadows and the image quality according to the actual demand was proposed in this paper. This scheme combined with technology of compressed sensing and Shamir`s (k,n)-threshold scheme, and realized the process of flexible adjustment in shadows by different observation rate. Experimental results confirm that the proposed scheme can reasonably adjust the relationship between the size of shadows and the image quality according to the actual requirements and the available bandwidth. The scheme has the certain practicality.