Miracle-dz/UniFAR-FTUs huggingface dataset:
Pretreatment Serum Cea as a Predictive Biomarker for the Response toNeoadjuvant Chemoradiotherapy: A Meta-Analysis in Rectal Cancer

Background: It is important to predict patients with rectal cancer responding well to neoadjuvant chemoradiotherapy (nCRT). Numerous studies have yielded inconsistent results regarding the relationship between pretreatment CEA level and the response to nCRT in patients with rectal cancer. We conducted a systematic review and meta-analysis of these studies to define the relationship between them. Methods: A literature search of all major databases was performed. A total of 14 previously published eligible studies including 3,705 cases were identified and included in this meta-analysis. Results: Normal CEA (<5 ng/ml) predicted improved pathological complete response (pCR) (FE: RR 3.33; 95% CI 2.57–4.31; P<0.00001) and good response (FE: RR 1.86; 95% CI 1.08–3.21; P < 0.00001) to nCRT. Moreover, Normal CEA was significantly associated with decreased poor response (RE: RR 0.78; 95% CI 0.73–0.83; P<0.00001) to nCRT. Conclusions: The current meta-analysis suggests that pretreatment normal CEA level is a useful predictive factor for response to neoadjuvant treatment in patients with rectal cancer. The validated predictive value of pretreatment CEA on pCR should be considered in the design of further clinical studies to determine the safety and efficacy of wait-and-watch approach.
Interpretation of the IR spectra of celadonites and glauconites in the region of OH-stretching frequencies

Abstract A method is given for quantitative analysis of IR spectra of dioctahedral micas in the OH-stretching region, which involves spectral decomposition and correlation of octahedral cation contents with integrated optical densities of the corresponding bands. It provides a basis for the study of order-disorder in these minerals and has allowed revision of the crystallochemical formulae of some glauconites and celadonites.
Corporate Social Responsibility in the Water Sector: How Material Practices and their Symbolic and Physical Meanings Form a Colonising Logic

This paper is a study and analysis of CSR and the current legal regulatory framework of Danish water companies. CSR in these hybrid organisations, which are privatised but politically driven, has been found to face various challenges in reaching the same level as private organisations. This paper shows that there are opportunities and barriers for CSR in these types of companies that in spite of–or maybe because of–their structural hybridity between managing a private as well as a political organisation makes these companies attractive in the arena of CSR. The opportunities for CSR in water companies seems more beneficial than for normal private businesses, since these organisations due to their structural hybridity are more closely connected to the decision makers of local government and the city council where some of the local politicians sit on the board of these companies. The barriers to CSR, found in the legal regulatory framework, diminishes the action radius of CSR in the light of efficiencies, price and cost reductions, and tight rules on which kinds of investments the companies can make. The argument in the paper is that the state and local government influence and the stakeholders both yield and limit the freedom of water companies to deal with CSR initiatives. This is also called a schism of CSR. The paper contributes to the CSR literature in its research in opportunities and barriers for CSR in hybrid organisations as a structural mix of private (business) and public administrations.
PRELIMINARY LIQUEFACTION POTENTIAL ANALYSIS OF VIJAYAWADA REGION

Experience from past earthquakes has demonstrated the vulnerability of structures to seismically induced ground deformation. During earthquake, soil can fail due to liquefaction with devastating effect such as landslides, lateral spreading, or large ground settlement. The phenomenon of liquefaction of soil had been observed for many years, but was brought to the attention of engineers after Niigata (1964) Alaska earthquakes (1964). Liquefaction is a phenomenon in which the strength and stiffness of a soil is reduced by earthquake shaking or other rapid loading. Liquefaction and related phenomena have been responsible for tremendous amounts of damage in historical earthquakes around the world (Borcherdt R.D 1991; Dobry R, 1981). During the Bhuj earthquake, India on 26th January 2001 (M=7.7) lot of damages had been occurred due to liquefaction and other ground failures (Rao and Mohanty, 2001). In this paper, a preliminary liquefaction hazard assessment was carried out using the available SPT data. From these investigations it was observed that a vast majority of liquefaction occurrences were associated with sandy soils and silty clays of low plasticity.
An eternal journey into an endless house: entrepreneurship as a hero-myth of the capitalist West

This thesis builds an argument of the entrepreneur as a mythical hero of the capitalist West. Entrepreneurship as a contemporary hero-myth is analyzed through the logic of Joseph Campbell's hero's journey theory, with evidence from the film 2001: A Space Odyssey and an article about the Finnish entrepreneur Jyri Lipponen published in Kauppalehti. By engaging in a genealogical study of entrepreneurship implicit in the myths of contemporary Western culture, and in its academic treatment, propositions are made for the future consideration of the phenomenon. Entrepreneurship is considered as rooting in a panhuman cognition of useful creation, with organizations being built upon the purposeful actions of a leading character – who tends to transform from an ordinary plebeii, through an entrepreneurial experience, to an emperor-manager. Entrepreneurship is considered from multiple philosophical angles, dominated by the becoming philosophy of Nietzsche, enriched by naturalist, pragmatist and Buddhist philosophies resulting in a holistic view of the phenomena. The propositions made lay a foundation wherefrom to embark into further critical studies of entrepreneurship as a cultural and social phenomenon. Tässä tutkielmassa rakennetaan väite yrittäjyydestä läntisen kapitalistisen kulttuurin sankarimyyttinä. Tämä nykyajan myytti analysoidaan Joseph Campbellin sankarin matkateorian avulla, aineistona kuvamateriaali 2001: Avaruusseikkailu-elokuvasta sekä Kauppalehden artikkeli yrittäjä Jyri Lipposesta. Yrittäjyyden alkuperän tutkiminen läntisen nykykulttuurin piilevänä myyttinä johtaa tutkielmassa esitettyihin ehdotuksiin. Yrittäjyyden nähdään alkavan yleisinhimillisestä hyödyllisen luomisen kognitiosta, organisaatioiden syntyvän johtohahmon tarkoitushakuisten toimien ympärille. Tämä johtohahmo kokee muutoksen kansalaisesta hallitsija-johtajaksi yrittäjyyden kokemuksen kautta. Yrittäjyyttä katsotaan useista filosofisista näkökulmista, erityisesti Nietzschen prosessifilosofian kautta, lisäten naturalistista, pragmaattista ja buddhalaista filosofiaa holistiseen näkemykseen. Tutkielmassa esitetyt ehdotukset avaavat mahdollisuuksia uusiin kriittisiin tutkimuksiin yrittäjyydestä kulttuurisena ja sosiaalisena ilmiönä.
Partial Hölder continuity of the spatial derivatives of the solutions to nonlinear parabolic systems with quadratic growth

L’accès aux archives de la revue « Rendiconti del Seminario Matematico della Università di Padova » (http://rendiconti.math.unipd.it/) implique l’accord avec les conditions générales d’utilisation (http://www.numdam.org/conditions). Toute utilisation commerciale ou impression systématique est constitutive d’une infraction pénale. Toute copie ou impression de ce fichier doit contenir la présente mention de copyright.
Reply to comment by John M. Juston et al. on “Spatial and temporal phosphorus distribution changes in a large wetland ecosystem”

Juston et al. [2014] pointed out that ZR2012 undermined their intentions with critical methodological faults, and followed up with outdated and potentially misleading conclusions. We beg to disagree with this statement since data interpolation of water and soil samples for spatial analysis is a well established and accepted methodology used in books and published scientific papers [Cressie, 1993; Goovaerts, 1997; Murphy et al., 2009]. The 49 stations mentioned in Juston et al. [2014] were only used for the analysis of longand short-term changes in total phosphorus (TP) concentrations during the period between 1995 and 2007 and only stations having complete data available during this time frame were included. However, the maps presented in Figure 2 of ZR2012 were developed using more data points and the stations were listed and explained in Table 1 of ZR2012. We are also attaching here new maps showing the station locations for clarification per season and per year (Figure 1). Moreover, data density considerations for the selected years were extensively discussed in ZR2012.
The Direction of Time

Internationally known for his work in the theory of probability, symbolic logic, analysis of space and time, and philosophical problems of quantum physics, Hans Reichenbach (1891-1953) was one of the twentieth century's most incisive philosophers of science. In this, his last book, first published in 1956, he brought all his previous research and insight to bear on the most intractable and intriguing problem in physics: the elusive nature of time. This far-sighted work of philosophy illuminates the metaphysical questions with which contemporary researchers in cosmology and particle physics must contend. Arguing as he did throughout his career that developments in scientific knowledge must influence philosophy, Reichenbach shows how completely the Kantian "a priori"and many of our most basic intuitions about the structure of space and timeare undermined by twentieth-century physics. He shows how the philosophical understanding of time is necessary to understanding contemporary problems of cosmology. This new edition of "The Direction of Time," published in the year of Reichenbach's centennial, includes an introduction by Hilary Putnam, one of Reichenbach's most eminent students, describing the metaphysical assumptions and arguments embedded in Reichenbach's philosophy, and their importance for the development of contemporary philosophy pf science. "
D-branes: the D/¯D solution.

Taming the supergravity description of non-BPS D-branes : the D/ ¯ D solution. Abstract: We obtain the supergravity solution which describes a bound state of D-string/anti-D-string pairs attached to different fixed planes of an orbifold, in type IIB string theory compactified on T 4 /Z 2. For parameters at which the conformal field theory point of view predicts stability, the solution displays a repulson-like singular-ity. However, we observe that a D-string/anti-D-string pair probe in this background becomes tensionless before reaching the singularity, suggesting a resolution by the en-hançon mechanism. Moreover, the force feels by this probe is attractive, in contrast to the repulsive behaviour observed in the non-BPS D-brane description.
TOWERS, AND THE PERIODIC HOMOLOGY OF INFINITE LOOPSPACES

Let K(n) be the n th Morava K-theory at a prime p, and let T(n) be the telescope of a vn-self map of a finite complex of type n. In this paper we study the K(n)∗-homology of ∞ X, the 0 th space of a spectrum X, and many related matters. We give a sampling of our results. Let PX be the free commutative S-algebra generated by X: it is weakly equivalent to the wedge of all the extended powers of X. We construct a natural map sn(X) : LT(n)P(X) → LT(n)� ∞ ( ∞ X)+ of commutative algebras over the localized sphere spectrum LT(n)S. The induced map of commutative, cocommutative K(n)∗-Hopf algebras sn(X)∗ : K(n)∗(PX) → K(n)∗( ∞ X), satistfies the following properties. It is always monic. It is an isomorphism if X is n-connected, �n+1(X) is torsion, and T(i)∗(X) = 0 for 1 ≤ i ≤ n−1. It is an isomorphism only if K(i)∗(X) = 0 for 1 ≤ i ≤ n − 1. It is universal: the domain of sn(X)∗ preserves K(n)∗-isomorphisms, and if F is any functor preserving K(n)∗-isomorphisms, then any nat- ural transformation F(X) → K(n)∗( ∞ X) factors uniquely through sn(X)∗. The construction of our natural transformation uses the telescopic functors constructed and studied previously by Bousfield and the au- thor, and thus depends heavily on the Nilpotence Theorem of Devanitz, Hopkins, and Smith. Our proof that sn(X)∗ is always monic uses Topo- logical Andre-Quillen Homology and Goodwillie Calculus in nonconnec- tive settings.
A Documentation of the Philippines` Family Income and Expenditure Survey

The quality of poverty estimates relies heavily on the data sources. One of the sources of data for poverty estimation in the Philippines is the Family Income and Expenditure Survey (FIES). The FIES is the source of detailed information on income and expenditures of Filipino families. Conducted by the National Statistics Office every three years, it is an input to the calculation of critical poverty data necessary to monitor the condition of the poor in the country. In this document, one will be able to look into how the FIES is administered, how it evolved through time, how the concepts of family and income are defined, what the survey covers, how much it costs to conduct the FIES, how detailed the survey questions are, how long it takes to complete the enumeration, and what the issues surrounding it are.
OLDOWAN RAW MATERIAL PROCUREMENT AND USE: EVIDENCE FROM THE KOOBI FORA FORMATION

Raw material availability has been shown to be a major factor affecting the material culture of Oldowan tool users. Studies of artefact provenance often focus on site-specific raw material availability. Here, we use data from primary and secondary sources of raw material to develop a model of basin-scale stone availability in the eastern Turkana Basin, during the KBS and Okote Members of the Koobi Fora Formation. ED-XRF was used as a method of characterizing raw material sources and artefacts using trace elements. This model is applied to the site of FxJj 50 to investigate transport and discard patterns.
Crypotococcal meningitis in a none-HIV infected five month old infant with rickets: Case report

Crypotococcal is an invasive fungal disease, now endemic in the tropics. It is largely transmitted through inhalation, but can be transmitted locally through skin and eyes. Mostly, it causes disease in immune compromised individuals, especially older children and adults, where it causes disseminated disease. Baby JG aged 5 months presented with a prodrome of respiratory symptoms. His anterior fontanel was wide and bulging, and had poor muscle tone. A week later, he developed convulsions, and a depressed sensorium. Haemogram showed a leucocytosis. Bone metabolism showed serum low phosphate and high alkaline phosphatase. Cerebrospinal fluid biochemistry was unremarkable, but microscopy was positive for Indian ink stain and crypotococcal antigen. HIV PCR test was negative. Clinical improvement was observed on institution of anti meningitic therapy, and intravenous fluconazole, vitamin D3 and calcium supplementation, but another spike was noted on day 7 of therapy. The findings of crypotococcal meningitis in HIV seronegative infant is very rare. Immune reconstitution syndrome may occur during treatment. High index of suspicion for cryptococcosis is needed in high risk children with sub-acute presentations of meningitis, and a relatively normal CSF cell counts and biochemistry. Routine fungal screening of CSF for all suspected children is justified.
Towards a standardized definition of room categories for healthcare facilities (RakaS)

National and international norms have defined various industry-wide room type categories. When trying to generate standardized key performance indicators [KPIs] in the non-medical support services of hospitals for the purpose of benchmarking between different hospitals, it became clear that the room category definitions employed so far are not detailed and specific enough for the healthcare industry to allow correct comparisons of costs. This is why a new standardized Room Categorization for Hospitals (RakaS) was set up, based on existing norms but defining rooms more specifically and in the greater detail necessary for the healthcare context. The new healthcare-specific room category standard allows not only the generation of KPIs suitable for benchmarking between the non-medical support services in hospitals, but also the more accurate allocation of costs and the capacity to define the characteristics of service delivery in service level agreements more precisely.
Working Papers / Documents De Travail Gender and Competition: Evidence from Academic Promotions in France Gender and Competition: Evidence from Academic Promotions in France Pierre-philippe Combes ‡

Differences in promotion across genders are still prevalent in many occupations. Recent work based on experimental evidence indicates that women participate less in or exert lower effort during contests. We exploit the unique features of the promotion system for French academics to look at women's attitudes towards competition in an actual labour market. Using data for academic economists over the period 1991-2008 we find that, conditional on entering the competition, there is no difference in promotions across the genders, which is difficult to reconcile with either discrimination or a poorer performance of women in contests. In contrast, women have a substantially lower probability than men to enter the promotion contest. Our data does not support that this gap is due to differences in costs or in preferences concerning department prestige, indicating that women are less willing than men to take part in contests. as well as participants at seminars at the LSE and Greqam for helpful suggestions and assistance.
Towards a Scalable Multiprocessor User-level Environment

Our previous research on NOVA has shown that a small and e cient virtualization environment can be built by using microkernel construction principles in the design of a virtualization environment [9]. In NOVA, virtual-machine monitors, device drivers and other system services run as user-level applications. The microhypervisor provides communication mechanisms and enforces temporal and spatial separation between the components running on top of it. Due to the increasing numbers of cores on a chip, even in embedded systems, support for multiple processors should be a primary objective in the design of any new user-level environment. In this paper we show how to construct a scalable multiprocessor user-level environment that requires only a minimal set of kernel abstractions. 1. Motivation
The changing ozone depletion potential of N2O in a future climate

Nitrous oxide (N2O), which decomposes in the stratosphere to form nitrogen oxides (NOx), is currently the dominant anthropogenic ozone‐depleting substance emitted. Ozone depletion potentials (ODPs) of specific compounds, commonly evaluated for present‐day conditions, were developed for long‐lived halocarbons and are used by policymakers to inform decision‐making around protection of the ozone layer. However, the effect of N2O on ozone will evolve in the future due to changes in stratospheric dynamics and chemistry induced by rising levels of greenhouse gases. Despite the fact that NOx‐induced ozone loss slows with increasing concentrations of CO2 and CH4, we show that ODPN2O for year 2100 varies under different scenarios and is mostly larger than ODPN2O for year 2000. This occurs because the traditional ODP approach is tied to ozone depletion induced by CFC‐11, which is also sensitive to CO2 and CH4. We therefore suggest that a single ODP for N2O is of limited use.
Comparison of grassland biomass estimation models based on MODIS data

To accurately estimate grassland biomass is of significance for the reasonable management of regional stock-raising and the evaluation of ecological benefit.Various vegetation indices and regression functions have been used in estimating grassland biomass by remote sensing data.Based on the field survey and MODIS data,and adopting the significant remote sensing-based vegetation indices including Normalized Difference Vegetation Index(NDVI),Enhanced Vegetation Index(EVI)and Modified Soil Adjusted Vegetation Index(MSAVI),three regression models(linear,power,and exponential functions)for each paired grassland biomass and vegetation index in Keerqinzuoyihou County,Inner Mongolia were established and compared.The results showed that grassland biomass could be well simulated by linear,power,and exponential functions,and exponential function performed best.Three vegetation indices(NDVI,EVI and MSAVI)had significant positive correlation with grassland biomass,and were suitable for the successful quantification of grassland biomass based on MODIS.MSAVI functioned most efficient with above-ground biomass(R2=0.900),and the simulation of total biomass was more effective than that of above-ground grassland biomass by using linear function with NDVI and EVI.
Daily Mean Sea Level and Short-Period Seiches

Slow water-level variations and short-period seiches are found at the outer ends of the tidal spectrum. In order to isolate these types of oscillation from the body of the tide it is necessary to filter the observations. In this paper the filter theory is briefly set out first and then two simple and practical filters are discussed. The one consists of symbol products of arithmetical means and can be used to detect the true variations of the daily mean sea level. The other, which is a product of differences, isolates short-period seiches fairly well.
Green's function retrieval by cross‐correlation in case of one‐sided illumination

The cross‐correlation of acoustic wave fields at two receivers yields the exact Green's function between these receivers, provided the receivers are surrounded by sources on a closed surface. In most practical situations the sources are located on an open surface and as a consequence the illumination of the receivers is one‐sided. In this Letter we discuss the conditions for accurate Green's function retrieval for the situation of one‐sided illumination. It appears that the Green's function retrieval method benefits from the fact that the earth is inhomogeneous, without relying on assumptions about disorder.
A Predator Susceptibility Model of Juvenile Salmon Survival and a Voronoi Tessellation-based Approach for Generating Hypothetical Forest Landscapes

In relating juvenile salmonid size to adult survival, past observational studies have shown mixed results, while modeling has been limited to regression methods lacking in ecological mechanism. This paper develops a simple 4-parameter model relating the survival of juvenile Chinook salmon (Oncorhynchus tshawytscha) to their size based on susceptibility to predation. The model is parameterized to test the hypothesis that there is a critical size for smolts beyond which they experience significantly lower mortality due to a reduction in gape-limited predatory pressure. The model is validated on spring-run Chinook salmon tagged in the Columbia River Basin, tracking either in-river survival during out-migration from hatcheries to Lower Granite Dam or adult returns for fish tagged at Lower Granite Dam and at the mouth of the Grande Ronde River returning to Bonneville Dam. The predator susceptibility model outperforms a generalized linear model for adult return data and for in-river survival when mortality is high, while providing interpretable parameters and a mechanistic structure. These results show strong support for the critical-size critical-period hypothesis of Beamish & Mahnken (2001) while giving a plausible functional form for the response. There is also evidence that larger fish realize greater survival increases from barging than smaller fish. This provides a framework through which interannual variations in size-dependent survival can be separated from overall survival, which could help guide management targets in both hatchery and dam management as well as wild habitat restoration.