Miracle-dz/UniFAR-FTUs huggingface dataset:
Research On Active Object Data Association Mining Technology Based on Surveillance Video

With the rapid development of industrialization and urbanization, the public order situation becomes more and more complicated. Video surveillance is a large number of operations used to obtain characteristics of the suspect. In gang crime, the relationship between the suspects is the key clue to solving cases, which is of great significance to the detection of cases. Similar path to get active object is the relationship of the most effective method by measuring the similarity of the object activity measurement path relationship between objects, the scope for activity area is small, the path the whole situation. However, in the surveillance video, criminal gangs and sometimes appear together, sometimes separately has led to the track do not yet have similar characteristics. To solve this problem, this paper statistics on the active object in the intersection when the size of the airspace to measure the relationship between them. Firstly, we study tagging technology, which the video is converted to objects, time and space structured data. Secondly, Impact of research activities in space-time domain model objects, given time and space of the domain based on the support and confidence calculation. Finally, the data mining algorithm is given. This research study to explore spatial and temporal activities of law has significance for video annotation, and association mining technology to provide new technical means, in the criminal investigation has important application value.
Prenatal dog-keeping practices vary by race: speculations on implications for disparities in childhood health and disease.

OBJECTIVE There is consistent evidence demonstrating that pet-keeping, particularly of dogs, is beneficial to human health. We explored relationships between maternal race and prenatal dog-keeping, accounting for measures of socioeconomic status that could affect the choice of owning a pet, in a demographically diverse, unselected birth cohort. DESIGN Self-reported data on mothers' race, socioeconomic characteristics and dog-keeping practices were obtained during prenatal interviews and analyzed cross-sectionally. Robust methods of covariate balancing via propensity score analysis were utilized to examine if race (Black vs White), independent of other participant traits, influenced prenatal dog-keeping. SETTING A birth cohort study conducted in a health care system in metropolitan Detroit, Michigan between September 2003 and November 2007. PARTICIPANTS 1065 pregnant women (n=775 or 72.8% Black), between ages 21 and 45, receiving prenatal care. MAIN OUTCOME MEASURES Participant's self-report of race/ethnicity and prenatal dog-keeping, which was defined as her owning or caring for > or =1 dog for more than 1 week at her home since learning of her pregnancy, regardless of whether the dog was kept inside or outside of her home. RESULTS In total, 294 women (27.6%) reported prenatal dog-keeping. Prenatal dog-keeping was significantly lower among Black women as compared to White women (20.9% vs 45.5%, P<.001), and remained significantly different even after propensity score analysis was applied. CONCLUSION Findings suggest that there are persistent racial differences in dog-keeping not fully explained by measures of socioeconomic status. Racial differences in prenatal dog-keeping may contribute to childhood health disparities.
Microembolic signals and carotid plaque characteristics in patients with asymptomatic carotid stenosis

Objective. To investigate the association between carotid plaque characteristics and the occurrence of cerebral microemboli signals (MES) and subsequent ischemic events in patients with asymptomatic carotid stenosis (ACS). Design. Sixty-two asymptomatic patients with 50–99% carotid stenosis underwent transcranial Doppler (TCD) monitoring to determine the relationship between MES and plaque characteristics. The patients were followed for 1 year, and the incidence of transient ischemic attack (TIA)/stroke was studied. Results. MES were found in 10/62 of the patients at baseline, and there was a significant difference between the patients with moderate stenosis and those with severe stenosis on the presence of MES (p = 0.016). Furthermore, MES were more frequently found in patients with irregular and/or heterogeneous plaques than in those with regular (p = 0.028) and/or homogeneous plaques (p = 0.021). The incidence of TIA/stroke occurred more frequently in patients with MES than those without MES (p = 0.009). The proportion of progressive carotid stenosis was 4/50 in the patients with 50–99% stenosis during 1 year follow-up. Conclusion. Asymptomatic patients (with 50–99% carotid stenosis) with MES presented a significantly increased frequency of severe stenosis, with irregular and heterogeneous plaques.
Immunology of Multiple Sclerosis

Abstract Multiple sclerosis (MS) is considered a prototypic autoimmune disease of the central nervous system (CNS). A complex genetic background with the HLA-DR15 haplotype as the main genetic risk factor and over 100 mostly immune-related minor risk alleles as well as several environmental factors contribute to the etiology of MS. With respect to pathomechanisms, autoimmune inflammation in early MS is primarily mediated by adaptive immune responses and involves autoreactive T cells, B cells, and antibodies, while the later, chronic stages of MS are characterized by a compartmentalized immune response in the CNS with activated microglia and macrophages. A host of immune cells and mediators can contribute to the autoimmune process, but CNS-related factors such as localization of lesions, vulnerability of oligodendrocytes, neurons/axons, and secondary metabolic changes all play a role in the heterogeneous expression of the disease, including different pathologic lesion patterns, neuroimaging findings, disease courses, and severity and response to treatment.
Standards from birth to maturity for height, weight, height velocity, and weight velocity: British children, 1965. I.

The accurate assessment of the physical growth and development of children has recently come to interest paediatricians and public health officers much more than hitherto. the assessment growth, in clinical for the first time, standards for height and weight velocity from birth to maturity, well as for height and weight attained year questions that the physician to concerning a child's are:
Effect of the use of probiotics in the treatment of children with atopic dermatitis; a literature review.

INTRODUCTION Atopic dermatitis (AD) is a disease that mainly affects the pediatric population involving chronic and repetitive inflammatory skin manifestations. Its evolution is known as atopic march, which is characterized by the occurrence of respiratory and food allergies. AIM To carry out a classical review of the state-of-theart scientific literature regarding the effect of probiotics on the treatment of children with AD. METHODS Searches were conducted in Medline and Lilacs through the portals PubMed (http://www.ncbi.nlm. nih.gov/pubmed/) and SciELO (http://www.scielo.br). There was a selection of the available publications in the period from 2001 to 2011, using the keywords atopic dermatitis and probiotics (in English and in Portuguese). RESULTS After applying the inclusion and exclusion criterias, we selected 12 case-control studies which were conducted in four European countries and Australia. The methodological quality of the studies was assessed according to the STROBE recommendations. Assessment of agreement among researches in classifying the quality of the articles showed excellent agreement (k = 1.00, 95%) with a total of 9 papers at B level. The majority of the studies (75%) indicated a beneficial biological effect of probiotics on AD, including protection against infections, enhancement of the immune response, inflammation reduction and changes in gut the flora. The remaining studies showed no beneficial effects according to the outcomes of interest. CONCLUSION The majority of the studies in the scientific literature in this review showed improvements in some inflammatory parameters and in intestinal microbiota and not exactly, changes in clinical parameters. However, the biological effects observed in most of them suggest the possibility of benefits of the use of probiotics as an adjuvant in the treatment of AD.
Bacterial phenylalanine and phenylacetate catabolic pathway revealed

Aromatic compounds constitute the second most abundant class of organic substrates and environmental pollutants, a substantial part of which (e.g., phenylalanine or styrene) is metabolized by bacteria via phenylacetate. Surprisingly, the bacterial catabolism of phenylalanine and phenylacetate remained an unsolved problem. Although a phenylacetate metabolic gene cluster had been identified, the underlying biochemistry remained largely unknown. Here we elucidate the catabolic pathway functioning in 16% of all bacteria whose genome has been sequenced, including Escherichia coli and Pseudomonas putida. This strategy is exceptional in several aspects. Intermediates are processed as CoA thioesters, and the aromatic ring of phenylacetyl-CoA becomes activated to a ring 1,2-epoxide by a distinct multicomponent oxygenase. The reactive nonaromatic epoxide is isomerized to a seven-member O-heterocyclic enol ether, an oxepin. This isomerization is followed by hydrolytic ring cleavage and β-oxidation steps, leading to acetyl-CoA and succinyl-CoA. This widespread paradigm differs significantly from the established chemistry of aerobic aromatic catabolism, thus widening our view of how organisms exploit such inert substrates. It provides insight into the natural remediation of man-made environmental contaminants such as styrene. Furthermore, this pathway occurs in various pathogens, where its reactive early intermediates may contribute to virulence.
A prospective randomized pilot study to evaluate predictors of response in serial core biopsies to single agent neoadjuvant doxorubicin or paclitaxel for patients with locally advanced breast cancer.

INTRODUCTION Response to neoadjuvant chemotherapy for locally advanced breast cancer can be correlated with long-term outcomes. Surrogate end-point biomarkers may be used to assess response to the treatment. Most reported studies assessed the effects of combination chemotherapy. We assessed the feasibility of obtaining serial core breast biopsies, and correlated rates of apoptosis, proliferation, and expression of related proteins at baseline, during, and after neoadjuvant single agent chemotherapy for locally advanced breast cancer with response. EXPERIMENTAL DESIGN Women with a histologically confirmed unresected T(3) or T(4) infiltrating carcinoma of the breast were eligible. The first 20 patients received three cycles of doxorubicin 90 mg/m(2) followed by three cycles of paclitaxel 250 mg/m(2), or the reverse. Nine women received four cycles of each (doxorubicin 60 mg/m(2) and paclitaxel 175 mg/m(2)). Cycles were administered 14 days apart with filgastrim. End points included: (a). clinical and pathological response; (b). serial apoptotic [terminal deoxynucleotidyl transferase (Tdt)-mediated nick end labeling] and proliferation (immunohistochemistry, IHC) rates; and (c). expression (IHC) of estrogen receptor, HER2, bcl2, and p53. RESULTS From April 1997 to June 2001, 29 women were randomized. Twelve patients (42%) had a clinical complete response (cCR), and 16 (55%) had a clinical partial response. Five women (17%) had a pathological complete response, 7 (24%) had microscopic residual disease, and 17 (58%) had macroscopic residual disease. Higher baseline apoptosis and proliferation were associated with an improved pathological response (P = 0.006 and 0.003, respectively). Among 14 evaluable patients, apoptosis increased in women who had a cCR to the first agent but not in women without a cCR. Estrogen receptor-positive patients had a worse pathological response (P = 0.004). CONCLUSIONS The selected regimen is efficacious. It is feasible to obtain serial core biopsies that are informative for studies of apoptosis and IHC. This clinical design can serve as a model for combining standard chemotherapy and novel agents.
Interactions between tumor subpopulations affecting their sensitivity to the antineoplastic agents cyclophosphamide and methotrexate.

Abstract The hypothesis that individual tumor subpopulations which differ in sensitivity to chemotherapeutic agents can influence each other9s drug sensitivity was investigated using a set of mouse mammary tumor subpopulations derived from the same tumor. In one set of experiments, syngeneic mice were given injections of cyclophosphamide (CY)-sensitive line 168 cells and relatively insensitive line 410 cells on opposite flanks. Other mice received bilateral injections of only 168 or only 410 cells. CY administration was begun 2 days later and continued once a week for 4 weeks. The sensitivity of line 168 tumors was not affected by line 410 tumors, but the sensitivity of line 410 tumors was increased by the presence of line 168 tumors. The ability of line 168 tumors to increase the CY-sensitivity of line 410 tumors was not altered by irradiating (400 rads) the hosts 2 days before tumor cell injection. Mice bearing line 168 tumors only or both line 168 and line 410 tumors were more sensitive to the acute toxic effects of single, high doses of CY than were the line 410 tumor-bearing mice, suggesting that effects on CY activation are responsible for the drug sensitivity interaction. In a second set of experiments, cells of subpopulations which differed in sensitivity to methotrexate (MTX) were cocultured in vitro in the presence or absence of MTX. In the presence of MTX-sensitive line 410.4 cells, the sensitivity of cells of lines 67 and 168 was increased. The sensitivity of cells of another relatively insensitive population, T68H clone 8, was not affected. Thus, the sensitivity of some mammary tumor subpopulations to both CY and MTX can be influenced by the presence of other subpopulations that differ, when tested alone, in sensitivity to these agents.
Transfer of knowledge from the specialist to the generalist by videoconferencing: effect on diabetes care

We conducted a 12-month prospective interventional study of videoconferencing between primary and secondary care. A treatment network consisting of a diabetes specialist and four general practitioners was established. The communications medium was PC-based videoconferencing via ISDN at 128 kbit/s. A total of 154 type 2 diabetic patients entered the study. The specialist was contacted 94 times via videoconferencing. Metabolic and haemodynamic parameters were significantly improved over the course of the study: the mean HbA1c level fell from 8.1% to 7.8%, systolic blood pressure from 156 to 148 mmHg and diastolic blood pressure from 88 to 83 mmHg. The study demonstrated that therapeutic counselling by videoconferencing is feasible in diabetes care and suggests that it reduces hospital admissions and improves the quality of care.
From the margins to mainstream?

This article looks at the youth musical cultures of bhangra and Asian underground alongside wider societal shifts relating to British Asian youth in recent decades. The article first examines previous youth studies research, primary media source material and data from qualitative interviews; it then looks at these twin hybrid musically expressive forms fusing Indian instrumentation and fashion which have been principally produced by second-generation British-born youth of Asian origin - a group who have hitherto not been particularly noteworthy in either UK pop lore or youth studies. The data presented in the main body of the article are based on a number of semi-structured interviews in which the subjects’ own discursive framing of, and qualitative reasons for, their actions and reactions to events and cultural products are given. The fieldwork was carried out at various bhangra and Asian underground musical events in London and Manchester, allowing a longitudinal picture to develop of British Asian music and its place in the representations and realities of Asian youth.
Pretend Play As Improvisation: Conversation in the Preschool Classroom

Contents: W.A. Corsaro, Foreword. Preface. Introduction: Play as Improvisational Performance. Play and Conversation. An Improvisational Theory of Children's Play. Studying Pretend Play in the Preschool Classroom. Performance Style and Performances. Joining the Performance: The Metapragmatics of Play Entry. The Improvisational Exchange: Using Metapragmatic Strategies to Negotiate the Play Frame. The Performance of Play: Children's Group Improvisations. Improvisation and Development.
The New Person-Specific Paradigm in Psychology

Most research methodology in the behavioral sciences employs interindividual analyses, which provide information about the state of affairs of the population. However, as shown by classical mathematical-statistical theorems (the ergodic theorems), such analyses do not provide information for, and cannot be applied at, the level of the individual, except on rare occasions when the processes of interest meet certain stringent conditions. When psychological processes violate these conditions, the interindividual analyses that are now standardly applied have to be replaced by analysis of intraindividual variation in order to obtain valid results. Two illustrations involving analysis of intraindividual variation of personality and emotional processes are given.
Smartkom: multimodal communication with a life- like character

SmartKom is a multimodal dialog system that combines speech, gesture, and mimics input and output. Spontaneous speech understanding is combined with the video-based recognition of natural gestures. One of the major scientific goals of SmartKom is to design new computational methods for the seamless integration and mutual disambiguation of multimodal input and output on a semantic and pragmatic level. SmartKom is based on the situated delegation-oriented dialog paradigm, in which the user delegates a task to a virtual communication assistant, visualized as a life-like character on a graphical display. We describe the SmartKom architecture, the use of an XML-based mark-up language for multimodal content, and some of the distinguishing features of the first fully operational SmartKom demonstrator.
Unsupervised Multi-View Feature Selection for Tumor Subtype Identification

Existing unsupervised feature selection algorithms are designed to extract the most relevant subset of features which can facilitate clustering and interpretation of the obtained results. However, these techniques are not directly applicable in many real-world situations in which one has access to datasets consisting of multiple views or dissimilar representations. By leveraging information from these different views one can obtain more robust and accurate results compared with single-view methods. In this paper Unsupervised Multi-View Feature Selection algorithm is used to simultaneously extract a relevant subset of features and to perform clustering that is consistent across different views. In the empirical evaluation of synthetic multi-view data we demonstrate the advantage of using the proposed algorithm over the use of its single-view analogue. We used the National Cancer Institute's NCI-60 panel dataset, exploiting information from various -omics representations to identify tumor subtypes based on very few requisite, biologically relevant features.
A childhood chemotherapy protocol improves overall survival among adults with T-lymphoblastic lymphoma

A broadly accepted standard treatment for adult T-lymphoblastic lymphoma (T-LBL) has not yet been defined. To address that issue, we retrospectively compared three chemotherapy regimens used to treat 110 adult patients with newly diagnosed T-LBL. These included two adult regimens (ECOG2993 and hyper-CVAD) and a childhood regimen (BFM-90). These intensive drug regimens are mainly used to treat childhood and adult acute lymphoblastic leukemia. They included induction, consolidation, and maintenance chemotherapy protocols and were administered over the course of 2 years. Seventy-five patients (80%) achieved a complete remission (CR). Within a median follow-up time of 31 months (range: 5–152 months), the 5-year overall survival (OS) and progression-free survival (PFS) rates were 47.7% (95% CI, 35.0–69.8%) and 45.7% (95% CI, 27.6–56.6%), respectively. Shorter survival was associated with age > 40 years, poor ECOG PS and bone marrow involvement. Elevated lactic dehydrogenase (LDH) level, Ann Arbor stage and International Prognostic Index (IPI) score had no prognostic value. The childhood chemotherapy regimen improved CR and the overall survival rate more than the adult regimen in patients aged < 40 years.
Placing Equity Front and Center

This article explores what it means for teacher education programs to place diversity front and center. Using a social justice perspective on teacher education, the author argues that schools and colleges of education need to radically transform their policies and practices if they are to become places where teachers and prospective teachers learn to become effective with students of all backgrounds in U.S. schools. Specifically, she suggests that teacher education programs need to take a stand on social justice and diversity, make social justice ubiquitous in teacher education, and promote teaching as a life-long journey of transformation. The author provides several examples of how to do this.
The Role of Experience in Professional Skepticism , Knowledge Acquisition , and Fraud Detection

Recent notable instances of accounting fraud have led to regulator and public concern over the failure of experienced auditors to detect frauds prior to the issuance of a company’s financial statements. In response, the AIPCA has issued a new auditing standard, SAS 99, Consideration of Fraud in a Financial Statement Audit, in an effort to help auditors better assess fraud risk, detect fraud symptoms, and sharpen professional judgment as to whether a fraud has actually been committed in a firm. The purpose of this study is to examine the role of experience in increasing professional skepticism, knowledge acquisition, and ability to detect fraud. We suggest that the typical audit environment does not provide auditors with the type of experience, i.e., practice and feedback with fraud, which is necessary for successful fraud detection. Results of an experiment indicate that audit novices who have received practice and feedback with fraud detection exhibit a higher level of skepticism and knowledge about fraud and are better able to detect a fraud when it exists than individuals with typical audit experience.
Computation of Diet Composition for Patients Suffering from Kidney and Urinary Tract Diseases with the Fuzzy Genetic System

Determination of dietary food consumed a day for patients with diseases in general, greatly affect the health of the body and the healing process, is no exception for people with kidney disease and urinary tract. This paper presents the determination of diet composition in the form of food subtance for people with kidney and urinary tract diseases with a genetic fuzzy approach. This approach combines fuzzy logic and genetic algorithms, which utilizing fuzzy logic fuzzy tools and techniques to model the components of the genetic algorithm and adapting genetic algorithm control parameters, with the aim of improving system performance. The Mamdani fuzzy inference model and fuzzy rules based on population parameters and generation are used to determine the probability of crossover and mutation, and was using In this study, 400 food survey data along with their substances was used as test material. From the data, a varying amount of population is established. Each chromosome has 10 genes in which the value of each gene indicates the index number of foodstuffs in the database. The fuzzy genetic approach produces 10 best food substance and their compositions. The composition of these foods has nutritional value in accordance with the number of calories needed by people with kidney and urinary tract diseases by type of food.