Miracle-dz/UniFAR-FTUs huggingface dataset:
Solving high objective problems in fixed interactions with the decision maker

In recent advancements towards handling high objective optimization problems, it is proposed to progressively integrate the decision maker with the execution of an evolutionary multi-objective optimization algorithm. Preferences from the decision maker are accepted at the intermediate steps of the algorithm and a progress towards the most preferred point is made. In this paper, we extend the work on `progressively interactive evolutionary multi-objective optimization using value function' (PI-EMO-VF) by allowing the optimization to be performed in a fixed number of interactions with the decision maker. In the PI-EMO-VF procedure, information is accepted from the decision maker, which is utilized by the evolutionary algorithm to perform a focused search in the region of interest. However, it is not possible to restrict the number of interactions required to handle an optimization problem. This paper contributes towards, solving the optimization problem in a pre-decided number of decision maker calls. Once the available budget of decision maker calls are known, it is optimally utilized to get close to the most preferred point on the Pareto-frontier. The paper evaluates the performance of the modified PI-EMOVF algorithm on two, three and five objective test problems. A comparative study is performed against the previous proposal for the PI-EMO-VF procedure.
A method to analyze communication bandwidth and pulse response of power lines with branches using backward impedance transform technique

In this research, a method to analyze frequency response and rectangular pulse response of branched power line is proposed. Many existing methods analyze the power line response by modelling the signal reflection paths from the branches. Those methods need to specifications of the paths, hence, more or less suffer from over-simplified reflection paths, especially when used on complicated network configurations. Unlike the existing methods, the proposed method requires no propagation path modelling. It first shrinks the branched network to a simple one-source-one-load network by using microwave theories to backward transform the impedances terminated at the power line branches to voltage source. Then, the voltage at the terminated loads can be determined by the expansion. The rectangular pulse response can be found by using invert fast Fourier transform of the series of frequency response. Comparison of the pulse response to widely known methods is provided.
Dynamics of Sylvatic Chagas Disease Vectors in Coastal Ecuador Is Driven by Changes in Land Cover

Background Chagas disease is a serious public health problem in Latin America where about ten million individuals show Trypanosoma cruzi infection. Despite significant success in controlling domiciliated triatomines, sylvatic populations frequently infest houses after insecticide treatment which hampers long term control prospects in vast geographical areas where vectorial transmission is endemic. As a key issue, the spatio-temporal dynamics of sylvatic populations is likely influenced by landscape yet evidence showing this effect is rare. The aim of this work is to examine the role of land cover changes in sylvatic triatomine ecology, based on an exhaustive field survey of pathogens, vectors, hosts, and microhabitat characteristics' dynamics. Methodology and Principal Findings The study was performed in agricultural landscapes of coastal Ecuador as a study model. Over one year, a spatially-randomized sampling design (490 collection points) allowed quantifying triatomine densities in natural, cultivated and domestic habitats. We also assessed infection of the bugs with trypanosomes, documented their microhabitats and potential hosts, and recorded changes in landscape characteristics. In total we collected 886 individuals, mainly represented by nymphal stages of one triatomine species Rhodnius ecuadoriensis. As main results, we found that 1) sylvatic triatomines had very high T. cruzi infection rates (71%) and 2) densities of T. cruzi-infected sylvatic triatomines varied predictably over time due to changes in land cover and occurrence of associated rodent hosts. Conclusion We propose a framework for identifying the factors affecting the yearly distribution of sylvatic T. cruzi vectors. Beyond providing key basic information for the control of human habitat colonization by sylvatic vector populations, our framework highlights the importance of both environmental and sociological factors in shaping the spatio-temporal population dynamics of triatomines. A better understanding of the dynamics of such socio-ecological systems is a crucial, yet poorly considered, issue for the long-term control of Chagas disease.
Self Esteem Support as a Moderator of the Impact of Job Stress.

ABSTRACT Many studiet on. occupational stress have examined the buffering effects on stress of different-variables. This study Woothesized that self esteem support would buffer the effects of job s_ress on depressive syMptoms. Subjects were 131 business adminittration students who were-also perhanently employed. Subjects completed questionnaires three times with a one-month period between administrations. The reassurance of social worth scale from the Scale.and,the revised Daily Hassles Scale were completed at time 2,. along with other items. Also completed at times 2 and 3 was a 10-item scale measuring depressive symptoms. Results of a regression-analysis indicated that the job stress x self-esteem support interaction significantly predicted later depressive symptoms, with prior depressive symptoms partialled. The findings are supportive of the hypothesis that self-esteem support buffers the impact of job stress, and imply that type of support, rather than amount or source of support may be the important factor in determining the impact of support on job stress. (NB)
Building variable resolution occupancy grid map from stereoscopic system — A quadtree based approach

In intelligent vehicle field, occupancy grid maps are popular tools for representing the environment. Usually, occupancy grids, mapping the environment as a field of uniformly distributed binary/ternary variables, are generated by various kinds of sensors (e.g. lidar, radar, monocular/binocular vision system). In literature, most of proposed occupancy grid mapping methods create array-based fixed-resolution maps in either cartesian, polar, or column/disparity spaces. The problems of such maps are accuracy deficiency and prohibitive memory cost when trying to increase the resolution. This paper addresses these issues by presenting a novel variable resolution occupancy grid map based on quadtree structure from stereovision measurements. In the proposed method, a quadtree-based grid map with a settled resolution is calculated from a stereoscopic system at first. Then, the previously created map adapts its resolution to actual stereo measurements by merging or splitting nodes in the quadtree structure. The principal advantage of the proposed method is the ability to improve map's accuracy. Meanwhile, compared with some existing methods, the stereo-vision based occupancy grid mapping algorithm is improved. Experimental results with real datasets demonstrate that the accuracy of grid map created by our method is promoted from decimeter to centimeter.
A visual language for sketching large and complex interactive designs

Informal, sketch-based design tools closely match the work practices of user interface designers. Current tools, however, are limited in the size and complexity of interaction that can be specified. We have created an advanced sketch-based visual language that allows for easy prototyping of large, complex interactive designs. In its current embodiment in the denim web design tool, the visual language allows designers to sketch reusable components for recurring page elements, such as navigation bars, as well as conditionals to illustrate and test transitions that depend on a user's input. Designers can also specify sites that accept richer user input than simple clicking. Our informal evaluation shows that these features allow designers with little programming experience to quickly create prototypes of large, complex web sites while still working inside an informal, sketch-based environment
Molecular Structure and Organization of the Wheat Genomic Manganese Superoxide

The genomic structure of an MnSOD gene in wheat was elucidated by sequencing a clone from a BAC library of a stripe-rust resistant wheat line. The clone was identified by hybridization with a wheat MnSOD cDNA. The gene consisted of six exons interrupted by five introns with a total length of 4770 nucleotides from the start codon to the termination codon. The wheat MnSOD gene was the longest among those sequenced from plant species. The transcription initiation site was preceded by a G+C-rich promoter without a TATA or CAAT box. The promoter contained many putative cis-acting regulatory elements including an ABA-responsive element, stress-responsive element, and GC-repeat, and several other structural features in common with the promoter of the rice MnSOD gene. A Stowaway-like transposable element was found in intron 5 of the wheat MnSOD gene, but further investigation revealed the transposable element was not present in all copies of the MnSOD genes
Outcomes of Palliative Weekly Low-Dose Gemcitabine-Cisplatin Chemotherapy in Anthracycline- and Taxane- Pretreated Metastatic Breast Cancer Patients

Purpose The combination of gemcitabine and cisplatin (GP) has been shown to be safe and efficacious for patients with metastatic breast cancer (MBC), pretreated with anthracyclines and taxanes. We assessed the efficacy and safety of weekly low-dose GP in patients with MBC. Methods We collected clinicopathological data from MBC patients who had been treated with gemcitabine, 800 mg/m2 plus cisplatin, 30 mg/m2 intravenously, on days 1 and 8 every 3 weeks, between January 2001 and November 2011 in Korea. Results The analysis included 294 patients previously treated anthracycline-xand taxane-based chemotherapies prior to GP (median age, 48 years [range, 28-78 years]; median follow-up duration, 63.9 months). Seventeen patients (5.8%) discontinued GP because of toxicities. The median progression-free survival (PFS) was 3.9 months (95% confidence interval [CI], 3.394.4 months) and the median overall survival (OS) was 27.7 months (95% CI, 17.6-37.8 months) months. Statistically significant factors for PFS were performance status (Eastern Cooperative Oncology Group, ≥2 vs. <2; hazard ratio [HR], 1.37; 95% CI, 1.02-1.85; p=0.037), distant disease-free interval (DDFI; ≤2 years vs. >2 years; HR, 1.66; 95% CI, 1.28-1.95, p<0.001), time interval from the diagnosis of metastasis to GP therapy (≤1 year vs. >1 year; HR, 1.48; 95% CI, 1.13-1.95, p<0.001), and presence of brain metastasis (HR, 1.47; 95% CI, 1.03-2.10; p=0.031). Similarly, DDFI (≤2 years vs. >2 years; HR, 2.07; 95% CI, 1.36-3.14; p<0.001) and the presence of brain metastasis (HR, 2.14; 95% CI, 1.27-3.61; p=0.004) were important factors for OS after GP treatment. Conclusion Weekly low-dose GP chemotherapy appears safe and effective for heavily pretreated MBC patients.
BRASSINOSTEROID UPREGULATED1, Encoding a Helix-Loop-Helix Protein, Is a Novel Gene Involved in Brassinosteroid Signaling and Controls Bending of the Lamina Joint in Rice1[W][OA]

Brassinosteroids (BRs) are involved in many developmental processes and regulate many subsets of downstream genes throughout the plant kingdom. However, little is known about the BR signal transduction and response network in monocots. To identify novel BR-related genes in rice (Oryza sativa), we monitored the transcriptomic response of the brassinosteroid deficient1 (brd1) mutant, with a defective BR biosynthetic gene, to brassinolide treatment. Here, we describe a novel BR-induced rice gene BRASSINOSTEROID UPREGULATED1 (BU1), encoding a helix-loop-helix protein. Rice plants overexpressing BU1 (BU1:OX) showed enhanced bending of the lamina joint, increased grain size, and resistance to brassinazole, an inhibitor of BR biosynthesis. In contrast to BU1:OX, RNAi plants designed to repress both BU1 and its homologs displayed erect leaves. In addition, compared to the wild type, the induction of BU1 by exogenous brassinolide did not require de novo protein synthesis and it was weaker in a BR receptor mutant OsbriI (Oryza sativa brassinosteroid insensitive1, d61) and a rice G protein alpha subunit (RGA1) mutant d1. These results indicate that BU1 protein is a positive regulator of BR response: it controls bending of the lamina joint in rice and it is a novel primary response gene that participates in two BR signaling pathways through OsBRI1 and RGA1. Furthermore, expression analyses showed that BU1 is expressed in several organs including lamina joint, phloem, and epithelial cells in embryos. These results indicate that BU1 may participate in some other unknown processes modulated by BR in rice.
Discovering and tracking influencer-influencee relationships between online communities

This paper addresses a new problem concerning the discovery and tracking of influencer-influencee relationships between communities in dynamic social networks. A weighted temporal multigraph is employed to represent the dynamics of the social networks. To discover and track influencer-influencee relationships over time, communities sharing common interests are first grouped together in meta-communities using a topic modeling approach. Then, influencer-influencee relationships are discovered and tracked using the transfer entropy causality method. Through extensive experiments on the DBLP research publication dataset, we empirically demonstrate the suitability of our model for the discovery of influencer-influencee relationships between communities and the tracking of such relationships over time.
PANICLE PHYTOMER2 (PAP2), encoding a SEPALLATA subfamily MADS-box protein, positively controls spikelet meristem identity in rice

In rice panicle development, new meristems are generated sequentially in an organized manner and acquire their identity in a time- and position-dependent manner. In the panicle of the panicle phytomer2-1 (pap2-1) mutant, the pattern of meristem initiation is disorganized and newly formed meristems show reduced competency to become spikelet meristems, resulting in the transformation of early arising spikelets into rachis branches. In addition, rudimentary glumes and sterile lemmas, the outermost organs of the spikelet, elongate into a leafy morphology. We propose that PAP2 is a positive regulator of spikelet meristem identity. Map-based cloning revealed that PAP2 encodes OsMADS34, a member of the SEPALLATA (SEP) subfamily of MADS-box proteins. PAP2/OsMADS34 belongs to the LOFSEP subgroup of MADS-box genes that show grass-specific diversification caused by gene duplication events. All five SEP subfamily genes in rice are expressed exclusively during panicle development, while their spatial and temporal expression patterns vary. PAP2 expression starts the earliest among the five SEP genes, and a low but significant level of PAP2 mRNA was detected in the inflorescence meristem, in branch meristems immediately after the transition, and in glume primordia, consistent with its role in the early development of spikelet formation. Our study provides new evidence supporting the hypothesis that the genes of the LOFSEP subgroup control developmental processes that are unique to grass species.
Kinematics Analysis of an Asymmetrical 3-DOF Spatial Parallel Manipulator

A novel asymmetrical spatial parallel robotic manipulator with three degrees of freedom (DOF) is proposed. The moving platform of the mechanism has two-translational and one-rotational DOF with respect to the fixed base. Motion output characteristics and the mobility of the manipulator are analyzed based on the screw theory. Solutions of position and velocity for both direct and inverse kinematics are derived. Furthermore, the singularity and the dexterity are discussed. The Jacobian matrix, mapping the input velocity vector space of the actuated joints into the output velocity vector space of the moving platfomr, is an identical 3 3 matrix, so the parallel mechanism is a free-singularity fully-isotropic one. Thus, this mechanism performs very well with regard to motion and force transmission and has potential applications in the field of industrial robots and medical devices. Keywords-Parallel Manipulator; Kinematic Analysis; Singularity; Dexterity; Screw theory
Abstract Hidden Markov Models: A Monadic Account of Quantitative Information Flow

Hidden Markov Models, HMM's, are mathematical models of Markov processes whose state is hidden but from which information can leak via channels. They are typically represented as 3-way joint probability distributions. We use HMM's as denotations of probabilistic hidden-state sequential programs, after recasting them as “abstract” HMM's, i.e. computations in the Giry monad D, and equipping them with a partial order of increasing security. However to encode the monadic type with hiding over state X we use DX→D2X rather than the conventional X→DX. We illustrate this construction with a very small Haskell prototype. We then present uncertainty measures as a generalisation of the extant diversity of probabilistic entropies, and we propose characteristic analytic properties for them. Based on that, we give a “backwards”, uncertainty-transformer semantics for HMM's, dual to the “forwards” abstract HMM's. Finally, we discuss the Dalenius desideratum for statistical databases as an issue in semantic compositionality, and propose a means for taking it into account.
Partitioning Clustering Algorithms for DataStream Outlier Detection

Recently many researchers have focused on mining data streams and they proposed many techniques and algorithms for data streams. They are data stream classification, data stream clustering, and data stream frequent pattern items and so on. Data stream clustering techniques are highly helpful to cluster the similar data items in data streams and also to detect the outliers, so they are called cluster based outlier detection. The main objective of this research work is to perform the clustering process and detecting the outliers in data streams. In this research work, two partitioning clustering algorithms namely CLARANS and E-CLARANS (Enhanced Clarans) are used for clustering and detecting the outliers in data streams. Two performance factors such as clustering accuracy and outlier detection accuracy are used for observation. By examining the experimental results, it is observed that the proposed ECLARANS clustering algorithm performance is more accurate than the existing algorithm CLARANS.
Endothelium-derived hyperpolarizing factors and vascular cytochrome P450 metabolites of arachidonic acid in the regulation of tone.

The discovery of prostacyclin and its endothelial origin established the idea of endothelium-derived vasoactive eicosanoids and led to the realization that endothelial cells were a source of autacoids that regulate vascular tone.1 2 In 1980, Furchgott and Zawadzki3 described endothelium-derived relaxing factor (EDRF) and presented evidence that EDRF was a lipoxygenase metabolite of arachidonic acid. Subsequent research indicated that EDRF was nitric oxide.4 Several laboratories have described an endothelium-derived vasodilating factor that is distinct from nitric oxide or prostacyclin.5 6 7 8 9 10 These laboratories reported that acetylcholine caused endothelium-dependent relaxation and hyperpolarization of vascular smooth muscle. The relaxations and hyperpolarizations were not altered by arginine analogs that inhibit nitric oxide synthase or inhibitors of cyclooxygenase or lipoxygenases. They were blocked by inhibitors of calcium-activated potassium channels such as tetraethylammonium or charybdotoxin but not by inhibitors of ATP-sensitive potassium channels such as glibenclamide. Subsequent studies indicated that this factor was released by other agonists including bradykinin and substance P. It was concluded that this vasodilating factor acts by opening calcium-activated potassium channels and hyperpolarizing the smooth muscle membrane. This factor has been termed endothelium-derived hyperpolarizing factor or EDHF. The article by Thollon and coworkers11 in this issue of Circulation Research further emphasizes the importance of EDHF in normal coronary arteries and arteries with regenerated endothelium. Several important insights are provided into the action and nature of EDHF by this work. First, this study demonstrates the importance of measuring membrane potential in defining the contribution of EDHF to the action of agonists. Hyperpolarization of vascular smooth muscle unequivocally defines EDHF activity. Second, the study indicates the importance of the resting membrane potential of the smooth muscle on the magnitude of the response to EDHF. Removal of the endothelial lining of porcine coronary arteries results in …
Feedback for high EEG alpha does not maintain performance or mood during sleep loss.

Can performance and mood during sleep loss be maintained by self-induced high EEG alpha activity? In a previous study, most of the performance and mood measures showed sleep-loss impairment regardless of EEG alpha level, but attention and reported sleepiness were less impaired for the high-alpha group (although the differences were of doubtful significance). A constructive replication was carried out. In Group A (N=10) auditory feedback was contingent on high alpha, and in Group B (N=10) auditory feedback was contingent on low alpha and low theta. All subjects were repeatedly measured on auditory vigilance, addition, immediate recall, and feelings of sleepiness for 40 hrs during which no sleep was permitted. Sixty min of EEG feedback were given during each block of 220 min. Group A did produce significantly more alpha for the first 24 hrs but this difference was not maintained. Both groups had significant sleep-loss impairment on all measures. There were no significant differences between the groups in the amount of impairment. Self-enhanced EEG alpha activity does not prevent impairment of performance or mood during sleep loss.