Miracle-dz/UniFAR-FTUs huggingface dataset:
Water Quality Observations from Space: A Review of Critical Issues and Challenges

Water is the basis of all life on this planet. Yet, approximately one in seven people in the world do not have access to safe water. Water can become unsafe due to contamination by various organic and inorganic compounds due to various natural and anthropogenic processes. Identifying and monitoring water quality changes in space and time remains a challenge, especially when contamination events occur over large geographic areas. This study investigates recent advances in remote sensing that allow us to detect and monitor the unique spectral characteristics of water quality events over large areas. Based on an extensive literature review, we focus on three critical water quality problems as part of this study: algal blooms, acid mine drainage, and suspended solids. We review the advances made in applications of remote sensing in each of these issues, identify the knowledge gaps and limitations of current studies, analyze the existing approaches in the context of global environmental changes, and discuss potential ways to combine multi-sensor methods and different wavelengths to develop improved approaches. Synthesizing the findings of these studies in the context of the three specific tracks will help stakeholders to utilize, share, and embed satellite-derived earth observations for monitoring and tracking the ever-evolving water quality in the earth’s limited freshwater reserves.
Herbivory Amplifies Adverse Effects of Drought on Seedling Recruitment in a Keystone Species of Western North American Rangelands

Biotic interactions can affect a plant’s ability to withstand drought. Such an effect may impact the restoration of the imperiled western North American sagebrush steppe, where seedlings are exposed to summer drought. This study investigated the impact of herbivory on seedlings’ drought tolerance for a keystone species in this steppe, the shrub Artemisia tridentata. Herbivory effects were investigated in two field experiments where seedlings were without tree protectors or within plastic or metal-mesh tree protectors. Treatment effects were statistically evaluated on herbivory, survival, leaf water potential, and inflorescence development. Herbivory occurrence was 80% higher in seedlings without protectors. This damage occurred in early spring and was likely caused by ground squirrels. Most plants recovered, but herbivory was associated with higher mortality during the summer when seedlings experienced water potentials between −2.5 and −7 MPa. However, there were no differences in water potential between treatments, suggesting that the browsed plants were less tolerant of the low water potentials experienced. Twenty months after outplanting, the survival of plants without protectors was 40 to 60% lower than those with protectors. The percentage of live plants developing inflorescences was approximately threefold higher in plants with protectors. Overall, spring herbivory amplified susceptibility to drought and delayed reproductive development.
The Feynman $i \epsilon$ in String Theory

The Feynman $i\varepsilon$ is an important ingredient in defining perturbative scattering amplitudes in field theory. Here we describe its analog in string theory. Roughly one takes the string worldsheet to have Lorentz signature when a string is going on-shell although it has Euclidean signature generically.
Polarization of prompt and afterglow emission of Gamma-Ray Bursts

Gamma-ray bursts and their afterglows are thought to be produced by an ultra-relativistic jet. One of the most important open questions is the outflow composition: the energy may be carried out from the central source either as kinetic energy (of baryons and/or pairs), or in electromagnetic form (Poynting flux). While the total observable flux may be indistinguishable in both cases, its polarization properties are expected to differ markedly. The prompt emission and afterglow polarization are also a powerful diagnostic of the jet geometry. Again, with subtle and hardly detectable differences in the output flux, we have distinct polarization predictions. In this review we briefly describe the theoretical scenarios that have been developed following the observations, and the now large observational datasets that for the prompt and the afterglow phases are available. Possible implications of polarimetric measurements for quantum gravity theory testing are discussed, and future perspectives for the field briefly mentioned.
Low-Γ jets from Compact Binary Mergers as Candidate Electromagnetic Counterparts to Gravitational Wave Sources

Abstract Compact binary mergers, with neutron stars or neutron star and black-hole components, are thought to produce various electromagnetic counterparts: short gamma-ray bursts (GRBs) from ultra-relativistic jets followed by broadband afterglow; semi-isotropic kilonova from radioactive decay of r-process elements; and late time radio flares; etc. If the jets from such mergers follow a similar power-law distribution of Lorentz factors as other astrophysical jets then the population of merger jets will be dominated by low-Γ values. The prompt gamma-rays associated with short GRBs would be suppressed for a low-Γ jet and the jet energy will be released as X-ray/optical/radio transients when a shock forms in the ambient medium. Using Monte Carlo simulations, we study the properties of such transients as candidate electromagnetic counterparts to gravitational wave sources detectable by LIGO/Virgo. Approximately 78% of merger-jets result in failed GRB with optical peaks 14-22 magnitude and an all-sky rate of 2-3 per year.
Soft X-ray Observations of AM Herculis from HEAO-1.

Extensive soft X-ray (0.1-1.5 keV) observations of AM Herculis are reported. The data, acquired during two pointed observations by HEAO 1 in 1978, span four binary cycles and reveal considerable detail in the 3.09 hour light curve. Rapid X-ray flickering is evident throughout the bright section of the light curve and is characterized by an average e-folding autocorrelation time of about 10 s. Analysis of the spectral data indicates a 30% variability; on occasion the X-ray spectrum becomes softer as the source intensity decreases. The current understanding of AM Her as an accreting magnetic white dwarf is discussed, and various models are related to the present HEAO-1 data.
Optimal planar leg geometry in robots and crabs for idealized rocky terrain

Natural terrain is uneven so it may be beneficial to grasp onto the depressions or ‘valleys’ between obstacles when walking over such a surface. To examine how leg geometry influences walking across obstacles with valleys, we (1) modeled the performance of a two-linkage leg with parallel axis ‘hip’ and ‘knee’ joints to determine how relative segment lengths influence stepping across rocks of varying diameter, and (2) measured the walking limbs in two species of intertidal crabs, Hemigrapsus nudus and Pachygrapsus crassipes, which live on rocky shores and granular terrains. We idealized uneven terrains as adjacent rigid hemispherical ‘rocks’ with valleys between them and calculated kinematic factors such as workspace, limb angles with respect to the ground, and body configurations needed to step over rocks. We first find that the simulated foot tip radius relative to the rock radius is limited by friction and material failure. To enable force closure for grasping, and assuming that friction coefficients above 0.5 are unrealistic, the foot tip radius must be at least 10 times smaller than that of the rocks. However, ratios above 15 are at risk of fracture. Second, we find the theoretical optimal leg geometry for robots is, with the distal segment 0.63 of the total length, which enables the traversal of rocks with a diameter that is 37% of the total leg length. Surprisingly, the intertidal crabs’ walking limbs cluster around the same limb ratio of 0.63, showing deviations for limbs less specialized for walking. Our results can be applied broadly when designing segment lengths and foot shapes for legged robots on uneven terrain, as demonstrated here using a hexapod crab-inspired robot. Furthermore, these findings can inform our understanding of the evolutionary patterns in leg anatomy associated with adapting to rocky terrain.
SIMPLIFIED HYDROSTATIC CARBON BURNING IN WHITE DWARF INTERIORS

We introduce two simplified nuclear networks that can be used in hydrostatic carbon burning reactions occurring in white dwarf interiors. They model the relevant nuclear reactions in carbon–oxygen white dwarfs approaching ignition in Type Ia supernova progenitors, including the effects of the main e−-captures and β-decays that drive the convective Urca process. They are based on studies of a detailed nuclear network compiled by the authors and are defined by approximate sets of differential equations whose derivations are included in the text. The first network, N1, provides a good first-order estimation of the distribution of ashes and it also provides a simple picture of the main reactions occurring during this phase of evolution. The second network, N2, is a more refined version of N1 and can reproduce the evolution of the main physical properties of the full network to the 5% level. We compare the evolution of the mole fraction of the relevant nuclei, the neutron excess, the photon energy generation, and the neutrino losses between both simplified networks and the detailed reaction network in a fixed temperature and density parcel of gas.
Establishment of a culture model for the prolonged maintenance of chicken feather follicles structure in vitro

Protocols allowing the in vitro culture of human hair follicles in a serum free-medium up to 9 days were developed 30 years ago. By using similar protocols, we achieved the prolonged maintenance in vitro of juvenile feather follicles (FF) microdissected from young chickens. Histology showed a preservation of the FF up to 7 days as well as feather morphology compatible with growth and/or differentiation. The integrity of the FF wall epithelium was confirmed by transmission electron microscopy at Day 5 and 7 of culture. A slight elongation of the feathers was detected up to 5 days for 75% of the examined feathers. By immunochemistry, we demonstrated the maintenance of expression and localization of two structural proteins: scaffoldin and fibronectin. Gene expression (assessed by qRT-PCR) of NCAM, LCAM, Wnt6, Notch1, and BMP4 was not altered. In contrast, Shh and HBS1 expression collapsed, DKK3 increased, and KRT14 transiently increased upon cultivation. This indicates that cultivation modifies the mRNA expression of a few genes, possibly due to reduced growth or cell differentiation in the feather, notably in the barb ridges. In conclusion, we have developed the first method that allows the culture and maintenance of chicken FF in vitro that preserves the structure and biology of the FF close to its in vivo state, despite transcriptional modifications of a few genes involved in feather development. This new culture model may serve to study feather interactions with pathogens or toxics and constitutes a way to reduce animal experimentation.
Search for the radiative transitions $\psi(3770)\to\gamma\eta_c$ and $\gamma\eta_c(2S)$

By using a 2.92 fb$^{-1}$ data sample taken at $\sqrt{s} = 3.773$ GeV with the BESIII detector operating at the BEPCII collider, we search for the radiative transitions $\psi(3770)\to\gamma\eta_c$ and $\gamma\eta_c(2S)$ through the hadronic decays $\eta_c(\eta_c(2S))\to K^0_SK^\pm\pi^\mp$. No significant excess of signal events above background is observed. We set upper limits at a 90% confidence level for the product branching fractions to be $\mathcal{B}(\psi(3770)\to\gamma\eta_c)\times \mathcal{B}(\eta_c\to K^0_SK^\pm\pi^\mp)<1.6\times10^{-5}$ and $\mathcal{B}(\psi(3770)\to\gamma\eta_c(2S))\times \mathcal{B}(\eta_c(2S)\to K^0_SK^\pm\pi^\mp)<5.6\times10^{-6}$. Combining our result with world-average values of $\mathcal{B}(\eta_c(\eta_c(2S))\to K^0_SK^\pm\pi^\mp)$, we find the branching fractions $\mathcal{B}(\psi(3770)\to\gamma\eta_c)<6.8\times10^{-4}$ and $\mathcal{B}(\psi(3770)\to\gamma\eta_c(2S))<2.0\times10^{-3}$ at a 90% confidence level.
OP-ICVA220242 1..9

OBJECTIVES: We have hypothesized that an endoscopically assisted transaxillary approach in the zero position would be able to improve visualization and allow safe surgery for thoracic outlet syndrome. METHODS: We performed surgery only for patients with certain objective findings, including blood flow disruption, low blood flow and accelerated blood flow in the subclavian artery demonstrated using Doppler sonography, narrowing of the scalene interval width between the anterior and middle interscalene muscles (interscalene base) or costoclavicular space demonstrated using Duplex ultrasonography or computed tomography angiography. The present study included 45 consecutive patients (50 limbs) who underwent endoscopic transaxillary first rib resection with scalenotomy and brachial plexus neurolysis. We assessed the intraoperative parameters, including the interscalene base, blood loss, operation time, patient satisfaction, preoperative and postoperative Quick Disability of the Arm, Shoulder and Hand and complications. RESULTS: The mean intraoperatively measured interscalene base width was 6.4 mm. All patients showed improvement after surgery. The outcome was excellent in 40% of cases, good in 48%, fair in 12% and poor in none. Pneumothorax was present in 6%. There were no other complications and no recurrences. Among patients who had been followed up for at least 2 years, the Quick Disability of the Arm, Shoulder and Hand score was significantly improved (42 before surgery vs 12 at final follow-up), especially in athletes relative to nonathletes (0.2 vs 16). The present approach achieved complete relief in 43% of cases overall (91% in athletes and 16% in non-athletes). TH O R A C IC VC The Author(s) 2022. Published by Oxford University Press on behalf of the European Association for Cardio-Thoracic Surgery. This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial License (https://creativecommons.org/licenses/bync/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com Interactive CardioVascular and Thoracic Surgery 2022, 35(4), ivac239 ORIGINAL ARTICLE https://doi.org/10.1093/icvts/ivac239 Advance Access publication 12 September 2022 CONCLUSIONS: Endoscopically assisted transaxillary first rib resection and brachial plexus neurolysis in the zero position are useful and safe for thoracic outlet syndrome, especially in athletes.
Non‐driver gene mutation analysis in a large cohort of polycythemia vera and essential thrombocythemia

A proportion of patients with polycythemia vera (PV) and essential thrombocythemia (ET) harbor non‐driver mutations associated with poor prognosis. In this study, we analyzed the frequency of non‐driver mutations in a large Japanese PV and ET cohort. Furthermore, we studied the relationship of these mutations and prognosis in Japanese patients.
System signatures and reliability functions

The concept of signature is a useful tool in the analysis of semicoherent systems with continuous and i.i. d. component lifetimes, especially for the comparison of different system designs and the computation of the system reliability. We provide various conversion formulas between the signature and the reliability function of the system through the corresponding vector of dominations. We also show how the signature can be computed from the reliability function via basic manipulations such as differentiation, coefficient extraction, and integration.
Meiotic defects in human oocytes: Potential causes and clinical implications

Meiotic defects cause abnormal chromosome segregation leading to aneuploidy in mammalian oocytes. Chromosome segregation is particularly error‐prone in human oocytes, but the mechanisms behind such errors remain unclear. To explain the frequent chromosome segregation errors, recent investigations have identified multiple meiotic defects and explained how these defects occur in female meiosis. In particular, we review the causes of cohesin exhaustion, leaky spindle assembly checkpoint (SAC), inherently unstable meiotic spindle, fragmented kinetochores or centromeres, abnormal aurora kinases (AURK), and clinical genetic variants in human oocytes. We mainly focus on meiotic defects in human oocytes, but also refer to the potential defects of female meiosis in mouse models.
Deep transfer learning compared to subject-specific models for sEMG decoders

Objective. Accurate decoding of surface electromyography (sEMG) is pivotal for muscle-to-machine-interfaces and their application e.g. rehabilitation therapy. sEMG signals have high inter-subject variability, due to various factors, including skin thickness, body fat percentage, and electrode placement. Deep learning algorithms require long training time and tend to overfit if only few samples are available. In this study, we aim to investigate methods to calibrate deep learning models to a new user when only a limited amount of training data is available. Approach. Two methods are commonly used in the literature, subject-specific modeling and transfer learning. In this study, we investigate the effectiveness of transfer learning using weight initialization for recalibration of two different pretrained deep learning models on new subjects data and compare their performance to subject-specific models. We evaluate two models on three publicly available databases (non invasive adaptive prosthetics database 2–4) and compare the performance of both calibration schemes in terms of accuracy, required training data, and calibration time. Main results. On average over all settings, our transfer learning approach improves 5%-points on the pretrained models without fine-tuning, and 12%-points on the subject-specific models, while being trained for 22% fewer epochs on average. Our results indicate that transfer learning enables faster learning on fewer training samples than user-specific models. Significance. To the best of our knowledge, this is the first comparison of subject-specific modeling and transfer learning. These approaches are ubiquitously used in the field of sEMG decoding. But the lack of comparative studies until now made it difficult for scientists to assess appropriate calibration schemes. Our results guide engineers evaluating similar use cases.
SIRT1/Notch1 signal axis involves in the promoting effect of Segetalin B on bone formation

Phytoestrogens are a class of potential natural medicines for treating postmenopausal osteoporosis (PMOP). Segetalin B (SB) is a cyclic peptide compound showing estrogenic activity. This study reports the effect of SB on bone formation among ovariectomized (OVX) rats. The bone marrow mesenchymal stem cells (BMSCs) from OVX rats were cultured in vitro. Alizarin Red staining was utilized to observe the effect of SB on the mineralization of BMSCs. The levels of alkaline phosphatase (ALP), osteocalcin, bone morphogenetic protein (BMP‐2), and Sirtuin 1 (SIRT1) activities were detected. The OVX rats were treated with SB in vivo. Micro‐CT was utilized for imaging analysis. Urine calcium and phosphorus, and ALP activity in bone marrow were assayed. Western blot analysis and immunofluorescence were incorporated to detect protein expressions in vitro and in vivo. The results showed that SB dose‐dependently promoted mineralization of OVX rat‐derived BMSCs in vitro increased the level of Osteocalcin, BMP‐2, ALP, and SIRT1 activity. Moreover, it upregulated expressions of Runx2, Osterix, and SIRT1, downregulated expressions of Notch intracellular domain (NICD), acetyl‐NICD, and hairy and enhancer of split 1 (Hes1). In addition, SB treatment significantly decreased bone loss, inhibited calcium and phosphorus loss, elevated ALP activity, upregulated Runx2, Osterix, and SIRT1, and downregulated NICD and Hes1 in OVX rats in vivo. However, EX527, a SIRT1‐selective inhibitor, could reverse the above effects of SB in vitro or in vivo. These results indicate that SB is a potential natural medicine to improve PMOP. Thus, its mechanism of promoting bone formation involves the SIRT1/Notch1 signaling axis.
Destination Memory for Self-Related Information: When I Tell Elvis Presley about My Favorite Food

ABSTRACT Destination memory, the ability to remember to whom information was previously delivered, has found to be influenced by social processing and social interactions. This memory has also been shown to be compromised in normal aging. Our paper investigated whether older adults would demonstrate better destination memory for self-related information than for general information. Methods: We asked younger adults and older adults to tell self-related information (e.g., “I like Chinese food”) and semantic information (e.g., “the moon is smaller than the sun”) to pictures of celebrities (e.g., Elvis Presley). Results: Analysis showed higher destination memory for self-related information than for semantic information in older adults and younger adults. Discussion: Older adults may draw on self-related information to improve memory and social interactions.
Syndecan‐4 and stromal cell‐derived factor‐1 alpha functionalized endovascular scaffold facilitates adhesion, spreading and differentiation of endothelial colony forming cells and functions under flow and shear stress conditions

Abstract Acellular vascular scaffolds with capture molecules have shown great promise in recruiting circulating endothelial colony forming cells (ECFCs) to promote in vivo endothelialization. A microenvironment conducive to cell spreading and differentiation following initial cell capture are key to the eventual formation of a functional endothelium. In this study, syndecan‐4 and stromal cell‐derived factor‐1 alpha were used to functionalize an elastomeric biomaterial composed of poly(glycerol sebacate), Silk Fibroin and Type I Collagen, termed PFC, to enhance ECFC‐material interaction. Functionalized PFC (fPFC) showed significantly greater ECFCs capture capability under physiological flow. Individual cell spreading area on fPFC (1474 ± 63 μm2) was significantly greater than on PFC (1187 ± 54 μm2) as early as 2 h, indicating enhanced cell–material interaction. Moreover, fPFC significantly upregulated the expression of endothelial cell specific markers such as platelet endothelial cell adhesion molecule (24‐fold) and Von Willebrand Factor (11‐fold) compared with tissue culture plastic after 7 days, demonstrating differentiation of ECFCs into endothelial cells. fPFC fabricated as small diameter conduits and tested using a pulsatile blood flow bioreactor were stable and maintained function. The findings suggest that the new surface functionalization strategy proposed here results in an endovascular material with enhanced endothelialization.