Miracle-dz/UniFAR-FTUs huggingface dataset:
Spatial ability and motor performance: assessing mental rotation processes in elite and novice athletes.

Expérimental and brain imaging studies provide strong évidence for thé involvement of motor processes in spatial ability problems, such as mental rotation tasks. This study was designed to assess thé relationship between motor performance in sport and mental rotation problems solving. Elite and novice athlètes in varions sports completed two spatial ability tasks thé Mental Rotation Test (MRT Vandenberg & Kuse, 1978) and thé Movement Imagery Spécifie Test (MIST), sport spécifie training and MRT results (experiments 1 &• 2 Moreau, Clerc, Mansy-Dannay, Guerrien, 2010). If motor processes are décisive in spatial ability tasks, we shouldfind différences favoring individuals involved in activities that require complex motor skills. Interestingly, we found a significant relationship between sports performance, activity, sport-specific training and MRT results (experiment 1 &• 2). In addition, thé well-documented gender effect on thé MRT was confirmed (experiments 1 &• 2). Results also underlined that élite athlètes gained efficiency by using flexible stratégies, which can be adjusted to thé particular problems encountered (experiment 2). Thèse results help fostering our understanding of thé relationship between motor représentations, spatial abilities and performance in sports. They are discussed in terms of their implications to général spatial ability models and to training procédures or sports advertising.
On the use of Dynamic Programming in eco-driving cycle computation for electric vehicles

This paper considers the problem of eco-driving for electric cars. This problem is formulated as an Optimal Control Problem (OCP) aiming at minimizing the vehicle's energy consumption over fixed time and distance horizons. The impact of battery parameter variations and auxiliary power demands on the optimal vehicle velocity computation are studied from a model complexity viewpoint. Simulation results are presented and discussed to illustrate the suggested simplifications.
Big Data and Journalism

Big data is a social, cultural, and technological phenomenon—a complex amalgamation of digital data abundance, emerging analytic techniques, mythology about data-driven insights, and growing critique about the overall consequences of big-data practices for democracy and society. While media and communication scholars have begun to examine and theorize about big data in the context of media and public life broadly, what are the particular implications for journalism? This article introduces and applies four conceptual lenses—epistemology, expertise, economics, and ethics—to explore both contemporary and potential applications of big data for the professional logic and industrial production of journalism. These distinct yet inter-related conceptual approaches reveal how journalists and news media organizations are seeking to make sense of, act upon, and derive value from big data during a time of exploration in algorithms, computation, and quantification. In all, the developments of big data potentially have great meaning for journalism’s ways of knowing (epistemology) and doing (expertise), as well as its negotiation of value (economics) and values (ethics). Ultimately, this article outlines future directions for journalism studies research in the context of big data.
A Worldwide Survey of Human Male Demographic History Based on Y-SNP and Y-STR Data from the HGDP–CEPH Populations

We have investigated human male demographic history using 590 males from 51 populations in the Human Genome Diversity Project - Centre d’Étude du Polymorphisme Humain worldwide panel, typed with 37 Y-chromosomal Single Nucleotide Polymorphisms and 65 Y-chromosomal Short Tandem Repeats and analyzed with the program Bayesian Analysis of Trees With Internal Node Generation. The general patterns we observe show a gradient from the oldest population time to the most recent common ancestors (TMRCAs) and expansion times together with the largest effective population sizes in Africa, to the youngest times and smallest effective population sizes in the Americas. These parameters are significantly negatively correlated with distance from East Africa, and the patterns are consistent with most other studies of human variation and history. In contrast, growth rate showed a weaker correlation in the opposite direction. Y-lineage diversity and TMRCA also decrease with distance from East Africa, supporting a model of expansion with serial founder events starting from this source. A number of individual populations diverge from these general patterns, including previously documented examples such as recent expansions of the Yoruba in Africa, Basques in Europe, and Yakut in Northern Asia. However, some unexpected demographic histories were also found, including low growth rates in the Hazara and Kalash from Pakistan and recent expansion of the Mozabites in North Africa.
Effects of Cocaine-Positive Urine Screens on Serum Thyrotropin Levels in Patients Admitted to an Inpatient Mental Health Unit

Objective To assess the effect of a positive urine screen for cocaine on thyrotropin (TSH, also thyroid-stimulating hormone) concentrations. Methods In this retrospective cohort study, patients admitted to the mental health unit at an academic inpatient setting with a diagnosis of cocaine dependence or cocaine intoxication were routinely screened with urine drug toxicology tests and TSH concentrations. TSH concentrations from patients who tested positive for cocaine on urine toxicology were compared with patients having negative cocaine screenings. Results A total of 192 patients were included: 122 with a positive cocaine screen and 70 with a negative cocaine screen. All patients were screened using a highly sensitive TSH assay. A positive cocaine screen was not associated with a statistically significant difference in TSH concentrations compared with a negative cocaine screen. The percentage of patients with hypothyroidism (TSH >4.50 &mgr;IU/mL) or hyperthyroidism (TSH <0.40 &mgr;IU/mL) were similar in both study groups. Conclusions The study failed to show that a positive urine screen for cocaine was associated with a significant effect on serum TSH levels in patients admitted to a mental health unit with a diagnosis of cocaine dependence or cocaine intoxication. Our findings support those of a prior study that cocaine use does not affect routine thyroid function tests. The present study does not support the clinical practice of ordering a serum TSH screening test on patients admitted to inpatient psychiatry units soley because the urine screen is positive for cocaine.
Approximate Objects and Approximate Theories

We propose to extend the ontology of logical AI to include approximate objects, approximate predicates and approximate theories. Besides the ontology we treat the relations among different approximate theories of the same phenomena. Approximate predicates can’t have complete if-and-only-if definitions and usually don’t even have definite extensions. Some approximate concepts can be refined by learning more and some by defining more and some by both, but it isn’t possible in general to make them well-defined. Approximate concepts are essential for representing common sense knowledge and doing common sense reasoning. Assertions involving approximate concepts can be represented in mathematical logic. A sentence involving an approximate concept may have a definite truth value even if the concept is ill-defined. It is definite that Mount Everest was climbed in 1953 even though exactly what rock and ice is included in that mountain is ill-defined. Likewise, it harms a mosquito to be swatted, although we haven’t a sharp notion of what it means to harm a mosquito. Whatif(x,p), which denotes what x would be like if p were true, is an important kind of approximate object. The article treats successively approximate objects, approximate theories, and formalisms for describing how one object or theory approximates another. Our discussion will be adequate if it has as much clearness as the subject matter admits of, for precision is not to be sought for alike in all discussions, any more than in all the products of the crafts. —Aristotle, Nicomachean Ethics
Hybrid Mapping for the Assistance of Teleoperated Grasping Tasks

Teleoperating a robotic hand with the aid of a sensorized glove presents some particular problems. A certain problem is due to the kinematic differences between the human hand and the robotic hand, which do not allow a simple direct mapping of the sensor readings from the glove to the robotic hand. This problem is addressed with different types of mapping, but none of them is of general use. This paper proposes two new mappings within two existing mapping types, as well as a new hybrid mapping that combines the best features of these existing mapping types. This hybrid mapping allows intuitive free space movements (where the gesture is more important than the precise positions of the fingers) and grasp movements (where the precise positions of the fingers is more important than the gesture), despite kinematic differences between the human hand and the robotic hand. The approach has been implemented, and some illustrative examples are presented in this paper.
Positive Unlabeled Learning for Deceptive Reviews Detection

Deceptive reviews detection has attracted significant attention from both business and research communities. However, due to the difficulty of human labeling needed for supervised learning, the problem remains to be highly challenging. This paper proposed a novel angle to the problem by modeling PU (positive unlabeled) learning. A semi-supervised model, called mixing population and individual property PU learning (MPIPUL), is proposed. Firstly, some reliable negative examples are identified from the unlabeled dataset. Secondly, some representative positive examples and negative examples are generated based on LDA (Latent Dirichlet Allocation). Thirdly, for the remaining unlabeled examples (we call them spy examples), which can not be explicitly identified as positive and negative, two similarity weights are assigned, by which the probability of a spy example belonging to the positive class and the negative class are displayed. Finally, spy examples and their similarity weights are incorporated into SVM (Support Vector Machine) to build an accurate classifier. Experiments on gold-standard dataset demonstrate the effectiveness of MPIPUL which outperforms the state-of-the-art baselines.
The Abuse of Power

It is well known that statistical power calculations can be valuable in planning an experiment. There is also a large literature advocating that power calculations be made whenever one performs a statistical test of a hypothesis and one obtains a statistically nonsignificant result. Advocates of such post-experiment power calculations claim the calculations should be used to aid in the interpretation of the experimental results. This approach, which appears in various forms, is fundamentally flawed. We document that the problem is extensive and present arguments to demonstrate the flaw in the logic.
Isolation and characterization of Fap1, a fimbriae‐associated adhesin of Streptococcus parasanguis FW213

An adhesin of Streptococcus parasanguis FW213, a primary colonizer of the tooth surface, has been purified from the culture medium by immunoaffinity chromatography. The purified protein has a molecular mass of 200 kDa and stains positively for carbohydrate. The amino‐terminal sequence indicated that this protein represented a unique streptococcal surface protein. Immunogold labelling of the bacterium indicated that this protein was associated with fimbriae and designated Fap1 (fimbriae‐associated protein). A polymerase chain reaction (PCR) product based on the amino terminus of Fap1 was used to probe an FW213 genomic library. A 9 kb fragment containing the fap1 gene was isolated and 2.5 kb have been sequenced. Generation of fap1 mutants by a single cross‐over (Campbell insertion) or a non‐polar allelic exchange abolished the expression of Fap1. The inactivation of fap1 resulted in a dramatic reduction in the expression of the long peritrichous fimbriae and adhesion to saliva‐coated hydroxylapatite (SHA). Northern blots probed with an internal gene fragment of fap1 hybridized to a 9 kb transcript, which suggests that fap1 is transcribed as a polycistronic message. These data demonstrate that Fap1 is a unique streptococcal adhesin that is involved in the assembly of S. parasanguis FW213 fimbriae and adhesion to SHA.
Rhythmic Influence of Top–Down Perceptual Priors in the Phase of Prestimulus Occipital Alpha Oscillations

Prior expectations have a powerful influence on perception, biasing both decision and confidence. However, how this occurs at the neural level remains unclear. It has been suggested that spontaneous alpha-band neural oscillations represent rhythms of the perceptual system that periodically modulate perceptual judgments. We hypothesized that these oscillations instantiate the effects of expectations. While collecting scalp EEG, participants performed a detection task that orthogonally manipulated perceptual expectations and attention. Trial-by-trial retrospective confidence judgments were also collected. Results showed that, independent of attention, prestimulus occipital alpha phase predicted the weighting of expectations on yes/no decisions. Moreover, phase predicted the influence of expectations on confidence. Thus, expectations periodically bias objective and subjective perceptual decision-making together before stimulus onset. Our results suggest that alpha-band neural oscillations periodically transmit prior evidence to visual cortex, changing the baseline from which evidence accumulation begins. In turn, our results inform accounts of how expectations shape early visual processing.
Impacts of Urbanization on River Systems in the Taihu Region, China

River systems are valuable to human beings; meanwhile, they are intensively influenced by human activities, especially urbanization. In this study, based on the data derived from topographic maps and remote sensing images, the temporal and spatial change of river system geomorphology in the Taihu Region over the past 50 years was investigated in conjunction with urbanization. Results demonstrated that the number of river systems decreased drastically, that the morphology of river channels changed into wider and straighter and that the structure of river network tended to simplify in the Taihu Region in recent 50 years. Meanwhile, the changes in river density, the water surface ratio, the river development coefficient, the main river area length ratio and the box dimension in the rapid urbanization period were much greater than those in the slow urbanization period, but the decrease of river sinuosity in the slow urbanization period was more intense. Moreover, the spatial differences of the changes in the river development coefficient were the largest, and the changes in the river indicators in the low-urbanized regions were the most intense. In addition, the changes in the water surface ratio had the closest correlation with urbanization, and the relational degrees between population urbanization and the changes in river systems were the largest. The results can provide a reliable basis to determine reasonable management and conservation strategies of river systems in the Taihu Region.
Role of MacMARCKS in Integrin-dependent Macrophage Spreading and Tyrosine Phosphorylation of Paxillin*

The cellular function of the MARCKS family of protein kinase C substrates is unknown. In this report, we present evidence that indicates a role for MacMARCKS, a member of the MARCKS family, in the integrin-dependent signal transduction pathways in macrophages. Using a dominant negative mutant of MacMARCKS, we showed that MacMARCKS participates in several integrin-dependent macrophage functions, including the phorbol ester-stimulated macrophage spreading, a process involving multiple integrins. The dominant negative mutant also blocks macrophage spreading on immune complex-coated surfaces, a process again requiring β2 integrin. More direct evidence of the role of MacMARCKS in the integrin-dependent pathway is the ablation of macrophage binding to complement iC3b-coated sheep erythrocytes by MacMARCKS mutant, suggesting an effect of this mutant on the avidity of complement receptor 3, a member of the β2 integrin family. To further evaluate the possible mechanism of MacMARCKS function, the integrin-dependent tyrosine phosphorylation of paxillin was examined. Concomitant with the inhibition of macrophage spreading and rosette formation, MacMARCKS mutant also inhibits integrin-dependent tyrosine phosphorylation of paxillin. Furthermore, immunofluorescent microscopy data showed that MacMARCKS and paxillin colocalize in the membrane ruffles at the leading edge of the spreading cells, providing a potential site and opportunity for MacMARCKS to participate in the regulation of integrin-dependent tyrosine phosphorylation of paxillin. Together, these data strongly suggest that MacMARCKS plays a role in integrin-dependent signal transduction pathways in macrophages.
STW project "Advanced relocatable multisensor system for buried landmine detection"

Delft University of Technology has just finished its major efforts in a most challenging project, supported by the Dutch Technology Foundation STW. This four-year project entitled "Advanced relocatable multi-sensor system for buried landmine detection" was the largest project in STW history. Within the scope of this project we have built up a unique expertise and knowledge in the whole GPR chain starting from all aspects in GPR technology and finishing with target classification and soil characterization. The paper describes the goals and results within this project.
Supermassive black hole binaries in gaseous and stellar circumnuclear discs: orbital dynamics and gas accretion

The dynamics of two massive black holes in a rotationally supported nuclear disc of mass M disc = 10 8 M⊙ is explored using N-body/smoothed particle hydrodynamics simulations. Gas and star particles are copresent in the disc. Described by a Mestel profile, the disc has a vertical support provided by turbulence of the gas, and by stellar velocity dispersion. A primary black hole of mass 4 x 10 6 M⊙ is placed at the centre of the disc, while a secondary black hole is set initially on an eccentric corotating orbit in the disc plane. Its mass is in a 1:1, 1:4, and 1:10 ratio, relative to the primary. With this choice, we mimic the dynamics of black hole pairs released in the nuclear region at the end of a gas-rich galaxy merger. It is found that, under the action of dynamical friction, the two black holes form a close binary in ∼10 Myr. The inspiral process is insensitive to the mass fraction in stars and gas present in the disc and is accompanied by the circularization of the orbit. We detail the gaseous mass profile bound to each black hole that can lead to the formation of two small Keplerian discs, weighing ≈2 per cent of the black hole mass, and of size ∼0.01 pc. The mass of the tightly (loosely) bound particles increases (decreases) with time as the black holes spiral into closer and closer orbits. Double active galactic nucleus activity is expected to occur on an estimated time-scale of ≤10 Myr, comparable to the inspiral time-scale. The double nuclear point-like sources that may appear during dynamical evolution will have typical separations of ≤10 pc.
Syntax-driven Analysis of Context-free Languages with Respect to Fuzzy Relational Semantics

A grammatical framework is presented that augments context-free production rules with semantic production rules that rely on fuzzy relations as representations of fuzzy natural language concepts. It is shown how the well-known technique of syntax-driven semantic analysis can be used to infer from an expression in a language defined in such a semantically augmented grammar a weak ordering on the possible worlds it describes. Considering the application of natural language query processing, we show how to order elements in the domain of a relational database scheme according to the degree to which they fulfill the intuition behind a given natural language statement like "Carol lives in a small city near San Francisco".
An Isochore-Like Structure in the Genome of the Flatworm Schistosoma mansoni

Eukaryotic genomes are compositionally heterogeneous, that is, composed by regions that differ in guanine–cytosine (GC) content (isochores). The most well documented case is that of vertebrates (mainly mammals) although it has been also noted among unicellular eukaryotes and invertebrates. In the human genome, regarded as a typical mammal, this heterogeneity is associated with several features. Specifically, genes located in GC-richest regions are the GC3-richest, display CpG islands and have shorter introns. Furthermore, these genes are more heavily expressed and tend to be located at the extremes of the chromosomes. Although the compositional heterogeneity seems to be widespread among eukaryotes, the associated properties noted in the human genome and other mammals have not been investigated in depth in other taxa. Here we provide evidence that the genome of the parasitic flatworm Schistosoma mansoni is compositionally heterogeneous and exhibits an isochore-like structure, displaying some features associated, until now, only with the human and other vertebrate genomes, with the exception of gene concentration.
In vitro effects of cyclooxygenase inhibitors in whole blood of horses, dogs, and cats.

OBJECTIVE To determine potency and selectivity of nonsteroidal anti-inflammatory drugs (NSAID) and cyclooxygenase- (COX-) specific inhibitors in whole blood from horses, dogs, and cats. SAMPLE POPULATION Blood samples from 30 healthy horses, 48 healthy dogs, and 9 healthy cats. PROCEDURE Activities of COX-1 and COX-2 were determined by measuring coagulation-induced thromboxane and lipopolysaccharide-induced prostaglandin E2 concentrations, respectively, in whole blood with and without the addition of various concentrations of phenylbutazone, flunixin meglumine, ketoprofen, diclofenac, indomethacin, meloxicam, carprofen, 5-bromo-2[4-fluorophenyl]-3-14-methylsulfonylphenyl]-thiophene (DuP 697), 5,5-dimethyl-3-(3-fluorophenyl)-4-(4-methylsulphonyl) phenyl-2(5H)-furan one (DFU), 3-(3,4-difluorophenyl)-4-(4-(methylsulfonyl)phenyl)-2-(5H)-furanone (MF-tricyclic), and celecoxib. Potency of each test compound was determined by calculating the concentration that resulted in inhibition of 50% of COX activity (IC50). Selectivity was determined by calculating the ratio of IC50 for COX-1 to IC50 for COX-2 (COX-1/COX-2 ratio). RESULTS The novel compound DFU was the most selective COX-2 inhibitor in equine, canine, and feline blood; COX-1/COX-2 ratios were 775, 74, and 69, respectively. Carprofen was the weakest inhibitor of COX-2, compared with the other COX-2 selective inhibitors, and did not inhibit COX-2 activity in equine blood. In contrast, NSAID such as phenylbutazone and flunixin meglumine were more potent inhibitors of COX-1 than COX-2 in canine and equine blood. CONCLUSIONS AND CLINICAL RELEVANCE The novel COX-2 inhibitor DFU was more potent and selective in canine, equine, and feline blood, compared with phenylbutazone, flunixin meglumine, and carprofen. Compounds that specifically inhibit COX-2 may result in a lower incidence of adverse effects, compared with NSAID, when administered at therapeutic dosages to horses, dogs, and cats.