Miracle-dz/UniFAR-FTUs huggingface dataset:
Mapping brain response variability in schizophrenia

Allocating electromagnetic auditory responses to active regions in the human auditory cortex can be difficult because of high interindividual variability of the relevant structures. Location and orientation of the primary auditory cortex (Heschl’s Gyrus) and the temporal plane vary with individual features such as age, gender, handedness, or between healthy subjects and patients with a psychiatric disorder (e.g., schizophrenia). Here, we propose a reference coordinate system that considers the individual MRIbased position, orientation and length of the primary auditory cortex to account for interindividual variability. Transformation of the M50 dipole localizations in this new HG-(Heschl’s-Gyrus)-coordinate system, accomplished for 10 healthy subjects and 10 schizophrenia patients, confirmed group difference more precisely than other registration methods. We suggest to use the HG-coordinate system for localization of functional measures and evaluation of brain activity differences between groups or measurement conditions.
How Space and Tool Availability Affect User Experience and Creativity in Interactive Surfaces?

As computing increasingly deals with our complex daily experiences, designers are challenged with new methods and ways of implementing complex interactions in limited user space and tools, but without hindering user experience and creativity. In this paper, we present the results of an empirical investigation regarding the effect of space and tool availability on user experience and creativity. The goal is to understand whether and how space and tool availability allow users to be more creative and improve their overall experience. To do so, we developed a connect-the-dots drawing multi-user application with a focus on having certain restrictions in size and specific tool availability. Based on this application, we conducted an empirical study with 38 users. For the evaluation, surveys, photos and observations were recorded and used in our analysis. The results showed that: (a) tool availability does not affect user creativity and experience and (b) space availability affects user creativity, collaboration and hedonic motivation (pleasure). Although our results are early, provide insights that tools' limitation does not hinder users' ability to be creative; and space availability is of great importance in creative activities.
Surgical procedures for benign prostatic hyperplasia: A nationwide survey in Japan, 2014 update

Abbreviations & Acronyms 5ARI = 5-alpha reductase inhibitor BPH = benign prostatic hyperplasia HIFU = high-intensity focused ultrasound HoLAP = holmium laser ablation of the prostate HoLEP = holmium laser enucleation of the prostate ILCP = interstitial laser coagulation of the prostate PVP = photoselective vaporization of the prostate TUBAL-T = transurethral balloon laser thermotherapy TUEB = transurethral enucleation with bipolar TUIP = transurethral incision of the prostate TULIP = transurethral laser incision the prostate TUMT = transurethral microwave thermotherapy TUNA = transurethral needle ablation TURF = transurethral radiofrequency heating TURis = transurethral resection in saline TURP = transurethral resection of the prostate TUVP/TURisV = transurethral vaporization of the prostate VLAP = visualized laser ablation of the prostate
Validade de construção em testes de equilíbrio: ordenação cronológica na apresentação das tarefas

Os testes de equilibrio da Escala de Desenvolvimento Motor de Rosa Neto1 sao constituidos por dez tarefas correspondentes as idades cronologicas de 2 a 11 anos e determinam a Idade Motora dos participantes. A ordem de apresentacao dos testes e crescente, partindo da idade cronologica da crianca e a idade motora baseia-se no sucesso ou fracasso em cada tarefa. O objetivo deste estudo foi analisar a validade de construcao dos testes motores em equilibrio, observando a ordenacao e os graus de dificuldade da tarefa. Participaram 76 criancas, com idade cronologica de 6 a 9 anos, que foram distribuidas em dois grupos: grupo controle, aplicacao dos testes em ordem crescente; grupo invertido, aplicacao dos testes em ordem decrescente. Os resultados nao apresentaram diferencas estatisticamente significativas no desempenho entre os grupos, indicando que a ordem de apresentacao dos testes nao interferiu no desempenho das criancas, independente da idade cronologica. Baixas taxas de sucesso ocorreram em algumas tarefas especificas, seguidas por sucesso em tarefas posteriores. Como os resultados demonstraram que os participantes conseguem executar tarefas seguintes a tarefa em que houve o fracasso, a idade motora apontada pela Escala de Desenvolvimento Motor pode estar subestimando o desenvolvimento motor dessas criancas. A variacao do desempenho das criancas nos testes sugere que o processo de desenvolvimento motor e nao linear. As tarefas motoras em equilibrio propostas na Escala de Desenvolvimento Motor apresentam validade de construcao. The equilibrium tests of the Rosa Neto1 Motor Development Scale are constituted by ten tasks related to the chronological ages from 2 to 11 years and they determine the participants Motor Age. The tests presentation order is crescent from the child chronological age and the motor age is based on the success or failure in each task. The aim of this study was to analyze the construction validity of the equilibrium motor tests observing the ordering the levels of task difficulty. 76 children with 6 to 9 years of chronological age participated and were assigned in two groups: control group, tests presentation in increased order; and inverted group, tests presentation in decreased order. The results did not revealed statistical significant differences between groups, which indicate that the presentation order of the tests did not interfere in the children performance, independently of the chronological age. Low success rates occurred in some specific tasks followed by success in advanced tasks. As the results revealed that the participants could perform the tasks after that in which the failure happened the motor age ascribed by the Motor Development Scale can underestimate the children motor development. The variation of the children performance in the tasks suggests that the motor development process is nonlinear. The equilibrium motor tasks purposed in the Motor Development Scale show construction validity.
Male Mating Constraints Affect Mutual Mate Choice: Prudent Male Courting and Sperm‐Limited Females

Costs of sperm production may lead to prudence in male sperm allocation and also to male mate choice. Here, we develop a life history–based mutual mate choice model that takes into account the lost‐opportunity costs for males from time out in sperm recovery and lets mate competition be determined by the prevailing mate choice strategies. We assume that high mating rate may potentially lead to sperm depletion in males, and that as a result, female reproduction may be limited by the availability of sperm. Increasing variation in male quality leads, in general, to increased selective mate choice by females, and vice versa. Lower‐quality males may, however, gain access to more fecund higher‐quality females by lowering their courting rate, thus increasing their sperm reserves. When faced with strong male competition for mates, low‐quality males become less choosy, which leads to assortative mating for quality and an increased mating rate across all males. With assortative mating, the frequency of antagonistic interactions (sexual conflict) is reduced, allowing males to lower the time spent replenishing sperm reserves in order to increase mating rate. This in turn leads to lower sperm levels at mating and therefore could lead to negative effects on female fitness via sperm limitation.
Utility of Subjective Sleep Assessment Tools for Healthy Preschool Children: A Comparative Study Between Sleep Logs, Questionnaires, and Actigraphy

Background Sleep pattern is an important factor in a child’s mental, behavioural and physical status. To evaluate the sleep patterns of children, subjective tools such as sleep logs and questionnaires are still widely used in addition to objective methods of sleep assessment. Despite the established correlation between subjective and objective sleep variables, the characteristic features of subjective assessment have not been elucidated. Methods To investigate the characteristics of parental sleep assessment (daily sleep log and brief questionnaire) in preschool children, a 7-day actigraphic sleep study was conducted in 48 healthy 5-year-old children. Results Sleep schedule variables in the parental reports generally correlated well with actigraphic assessment of sleep patterns; however, sleep periods were longer in parental reports than in actigraphic recordings. Although the daily sleep log was better correlated with actigraphy, the brief questionnaire showed a good correlation with sleep pattern on weekday actigraphic assessments. Parental reports recorded fewer than 10% of the night wakings recorded by actigraphy. Conclusions Subjective sleep assessments remain useful, although their utility depends on the purpose and size of the study in question. However, knowledge of the potential biases and characteristics of such assessments is essential for correct interpretation of the data.
Knowledge management for new product development

Purpose – The purpose of this paper is to present a holistic interpretation of the scope of knowledge management processes whose intent is to enhance the effectiveness of new product development (NPD). Design/methodology/approach – The paper reviews key concepts in NPD and knowledge management (KM), leading to propositions about the effective management of NPD‐relevant knowledge. It develops a structured, holistic model of organizational KM including practical mechanisms and processes for managing knowledge transfer.Findings – Effective knowledge management needs to: acknowledge the multiple organizational levels at which knowledge is deployed; support the production, elicitation and exchange of tacit knowledge as well as explicit, codified information; hence accommodate and enable both informal and formal, typically IS/IT enabled knowledge processes.Practical implications – KM is work‐in‐progress, not a one‐time search for an idealised state. Computer‐enabled information systems are necessary but not suff.
Heme Oxygenase-1: A Novel Key Player in the Development of Tolerance in Response to Organic Nitrates

Objective—Nitrate tolerance is likely attributable to an increased production of reactive oxygen species (ROS) leading to an inhibition of the mitochondrial aldehyde dehydrogenase (ALDH-2), representing the nitroglycerin (GTN) and pentaerythrityl tetranitrate (PETN) bioactivating enzyme, and to impaired nitric oxide bioactivity and signaling. We tested whether differences in their capacity to induce heme oxygenase-1 (HO-1) might explain why PETN and not GTN therapy is devoid of nitrate and cross-tolerance. Methods and Results—Wistar rats were treated with PETN or GTN (10.5 or 6.6 μg/kg/min for 4 days). In contrast to GTN, PETN did not induce nitrate tolerance or cross-tolerance as assessed by isometric tension recordings in isolated aortic rings. Vascular protein and mRNA expression of HO-1 and ferritin were increased in response to PETN but not GTN. In contrast to GTN therapy, NO signaling, ROS formation, and the activity of ALDH-2 (as assessed by an high-performance liquid chromatography–based method) were not significantly influenced by PETN. Inhibition of HO-1 expression by apigenin induced “tolerance” to PETN whereas HO-1 gene induction by hemin prevented tolerance in GTN treated rats. Conclusions—HO-1 expression and activity appear to play a key role in the development of nitrate tolerance and might represent an intrinsic antioxidative mechanism of therapeutic interest.
More realistic performance analysis for SDMA systems

The proliferating demands for mobile services propel us to develop more sophisticated techniques to overcome the limitation of the wireless radio resource. With the introduction of cell splitting and sectorization in cellular communications systems, system capacity can be significantly increased. Space division multiple access (SDMA) technology along this line has therefore gained a great deal of attention recently; intensive research on resource allocation for SDMA systems has been undertaken in the last few years. We carry out a more realistic performance analysis for a few resource allocation schemes in SDMA systems and obtain more accurate analytical results for blocking probability.
Gene Structure, Organization, Expression, and Potential Regulatory Mechanisms of Arginine Catabolism in Enterococcus faecalis

ABSTRACT Although Enteroccus faecalis is the paradigm for biochemical studies on the arginine deiminase (ADI) pathway of fermentative arginine catabolism, little genetic information exists on this pathway in this organism. We fill this important gap by characterizing, in an 8,228-bp region cloned from a λgt11 genomic library of E. faecalis, a five-gene cluster forming a transcriptional unit (revealed by Northern blots and primer extension in E. faecalis) that corresponds to the ADI operon. Four additional genes in the opposite DNA strand and one in the same DNA strand are also identified. Studies on the protein products, including heterologous expression and/or sequence comparisons, allow us to ascertain or propose functions for all but 1 of the 10 genes. The ADI operon genes, arcABCRD, encode, respectively, ADI, ornithine transcarbamylase, carbamate kinase, a putative Crp/Fnr-type regulator (ArcR), and a putative ornithine-arginine antiporter (ArcD). Arginine induces the expression of arcABCRD, most likely by means of two homologous ArgR/AhrC-type regulators encoded by two genes, argR1 and argR2, that precede arcABCRD in each DNA strand and that are transcribed monocistronically, their transcription being influenced differentially by glucose and arginine. Potential ArgR1/ArgR2 (double and single) binding sequences are found in the promoter regions of arcA and of argR1/argR2 themselves. In addition, putative binding sequences for ArcR and for CcpA are found, respectively, in the argR1/argR2 and arcA promoter regions. Of the three other genes identified, two form a transcriptional unit and encode a putative metal-sensitive transcriptional regulator (ArsR) and a cysteine protease.
Towards Automatic Integration of Or-BAC Security Policies Using Aspects

We propose a formal method to automatically integrate security rules regarding an access control pol- icy (expressed in Or-BAC) in Java programs. Given an untrusted application and a set of Or-BAC security rules, our method derives corresponding AspectJ aspects. Derived aspects modify the behaviour of the underlying program so as to meet the policy. Then, these aspects are weaved into the target program (using the AspectJ compiler). The result is a trusted program on which the security policy is enforced. This approach was applied in order to secure the behaviour of a travel agency application.
Energy-modulated quality of service: New scheduling approach

A conventional computational system architecture is formed by a processor which executes tasks and a management unit which controls the task execution routine according to a required strategy. Different strategies (or task scheduling schemes) are developed to maximize system performance. The system performance can be maximized according to the specification of each algorithm, if a task is schedulable. Poor energy condition in energy harvesting systems is one of the factors which cause conventional schedulers to fail. This paper presents a new scheduling approach which helps computation to survive in any energy-scarce environment by sacrificing small amounts of quality of service. Systems operating under the proposed approach can dynamically adapt its computational activity to the energy conditions. The paper also contains simulation results of a special design of FFT processor which works as a load for the proposed scheduling approach.
Prediction using Classification Technique for the Students' Enrollment Process in Higher Educational Institutions

In recent years, Indian higher educational institutes grow rapidly. There is more competition between institutes for attracting students to get enrollment in their institutes. The admission process is conducted every year at the institute and it results in the recording of large amounts of data. But, in most of the cases this data is not properly utilized (or analyzed) and results in wastage of what would otherwise be one of the most precious assets of the institutes. By applying the various data mining techniques on this data one can get valuable information and predictions can be done for the betterment of the admission process. This study presents data mining techniques for the enrollment process in MCA stream. These methods will help to improve the overall performance of the admission process at higher educational institutes. General Terms Data Mining, Classification, Data Preprocessing, KDD
Assessment of Competition between Fisheries and Steller Sea Lions in Alaska Based on Estimated Prey Biomass, Fisheries Removals and Predator Foraging Behaviour

A leading hypothesis to explain the dramatic decline of Steller sea lions (Eumetopias jubatus) in western Alaska during the latter part of the 20th century is a change in prey availability due to commercial fisheries. We tested this hypothesis by exploring the relationships between sea lion population trends, fishery catches, and the prey biomass accessible to sea lions around 33 rookeries between 2000 and 2008. We focused on three commercially important species that have dominated the sea lion diet during the population decline: walleye pollock, Pacific cod and Atka mackerel. We estimated available prey biomass by removing fishery catches from predicted prey biomass distributions in the Aleutian Islands, Bering Sea and Gulf of Alaska; and modelled the likelihood of sea lions foraging at different distances from rookeries (accessibility) using satellite telemetry locations of tracked animals. We combined this accessibility model with the prey distributions to estimate the prey biomass accessible to sea lions by rookery. For each rookery, we compared sea lion population change to accessible prey biomass. Of 304 comparisons, we found 3 statistically significant relationships, all suggesting that sea lion populations increased with increasing prey accessibility. Given that the majority of comparisons showed no significant effect, it seems unlikely that the availability of pollock, cod or Atka mackerel was limiting sea lion populations in the 2000s.
Robust 2D location of interest points by accumulation

Various interest point and corner definitions were proposed in the past with associated detection algorithms. We propose an intuitive and novel detection algorithm for finding the location of such features in an image. The detection is based on the edges in the original image. Interest points are detected as accumulation points where several edge tangent lines in a neighborhood are crossing. Edge connectivity is not used and thus detected interest points are robust to partial edges, outliers and edge extraction failures at junctions. One advantage of the approach is that detected interest points are not shifted in location when the original image is smoothed compared with other approaches. Experiments performed on Oxford and Cambridge reference databases allow us to show that the proposed detection algorithm performs better than 9 existing interest point detectors in terms of repeatability from multiple camera views.
Premarital Sexual Intercourse-Related Individual Factors Among Iranian Adolescents: A Qualitative Study

Background Understanding sexual behavior before marriage is relatively rare in the East, especially in Islamic societies, because sexuality is a sensitive subject for many Muslims. Objectives The purpose of this study was to identify premarital sexual intercourse-related individual factors among Iranian adolescents. Patients and Methods This qualitative study was performed on 30 students of Payame Noor university of Shiraz city, Iran, in 2014. The study sample includes male and female university students selected using the convenience sampling method. Semistructured interviews were used to collect data. All interviews were conducted by the researcher in a comfortable atmosphere and carried out without the presence of others. Each interview lasted between 30 - 20 minutes. Interviews continued until data saturation occurred. Data were analyzed using the qualitative content analysis method. Participation in the study was voluntary by obtaining an informed consent. Results The study included 30 participants, 56.6% (n = 17) males and 43.4% (n = 13) females. The age range of study, participants was from 19 to 25 years of age. Data analysis showed that three main categories extracted in shaping premarital sexual intercourse in adolescents: health beliefs, religious-spiritual beliefs, and character. Conclusions This study can help find a culturally appropriate intervention to delay sexual initiation and prevent sexual behavior before marriage in adolescents and young adults. The results of the present study have both experimental and theoretical implications for future research. Finally, this study is a form of shared experience that can help similar studies.
Online Social Networks and People's Psychology

Online Social Networks and People's Psychology Copyright Information: All rights reserved unless otherwise indicated. Contact the author or original publisher for any necessary permissions. eScholarship is not the copyright owner for deposited works. Learn more at http://www.escholarship. org/help_copyright. html#reuse PSYCHOLOGY, MEDICINE, AND ROBOTICS ONLINE SOCIAL NETWORKS AND PEOPLE’S PSYCHOLOGY SURF Conference Panel Session 3B By: Hai Hoang Mentor: Dr. Kaiping Peng, Psychology
In Human Macrophages the Complement Component C5a Induces the Expression of Oncostatin M via AP-1 Activation

Objective—Macrophages produce the cytokine oncostatin M (OSM), which beside other functions is also involved in inflammation. The complement component C5a mobilizes and activates these cells at inflammatory sites. We examined the effect of C5a on OSM production in human monocytes and in human monocyte-derived macrophages. Methods and Results—For macrophage transformation peripheral blood monocytes were cultivated for 8 to 10 days in the presence of human serum. C5a significantly increased in these cells OSM antigen as determined by specific ELISA and mRNA as quantitated by real-time polymerase chain reaction in these cells as well as in plaque macrophages. This effect was blocked by antibodies against the receptor C5aR/CD88 and by pertussis toxin. The C5a-induced phosphorylation of p38 and JNK and the C5a-induced increase in OSM production in macrophages was abolished by 2 p38 inhibitors and by a JNK inhibitor. Furthermore C5a increased the nuclear translocation of c-fos and c-jun. Using different OSM promoter deletion mutant constructs we show that the putative AP-1 element is responsible for activation of OSM promoter activity by C5a. Conclusion—Our data establish a link between the complement system and the gp130 receptor cytokine family with possible implications for the pathology of inflammatory diseases.