Miracle-dz/UniFAR-FTUs huggingface dataset:
Brittle-ductile analogue models of fold-and-thrust belts developed during progressive arching: the effect of viscous basal layer pinch-outs

espanolSe han realizado dos modelos analogicos fragil-ductiles de pliegues y cabalgamientos desarrollados durante un arqueamiento progresivo que estudian el efecto de la geometria de los limites de la capa ductil basal, perpendicular o paralela a la direccion de movimiento del apex (AMD). El objetivo es caracterizar la geometria del cinturon de pliegues y cabalgamientos, asi como su evolucion estructural. Cuando el limite de silicona es perpendicular al AMD la deformacion avanza hasta el limite de la silicona y el estiramiento paralelo al arco es acomodado por fallas normales y de salto en direccion. Despues, la cuna se engrosa y colapsa desarrollando unidades de desmantelamiento. Cuando los limites de silicona son paralelos al AMD se observan diferentes estilos estructurales a lo largo del cinturon de pliegues y cabalgamientos: un sistema imbricado vergente al antepais donde la silicona esta ausente y un sistema doble-vergente en presencia de la silicona, ambos separados por zonas de transferencia. Ademas, la ausencia de silicona da lugar a segmentos de cinturones de pliegues y cabalgamientos estrechos en planta y verticalmente engrosados. Ambos modelos son utiles para investigar el deposito de unidades de desmantelamiento y la distribucion de las diferencias estructurales observadas a lo largo del cinturon de pliegues y cabalgamientos del arco de Gibraltar. EnglishTwo brittle-ductile analogue models of fold-and-thrust belts developed during progressive arching that include silicone pinch-outs either perpendicular or parallel to the backstop apex motion direction (AMD) have been performed to test their role in fold-and-thrust belt geometry and structural evolution. When the silicone pinch-out is oriented perpendicular to the AMD the deformation front stagnates at the silicone pinch-out and arc-parallel lengthening is accommodated by normal and strike-slip faults. When deformation progresses, the wedge thickens and collapses, developing dismantling units. In contrast, when silicone pinch-outs are parallel to the AMD, different structural styles appear along the fold-and-thrust belt: a foreland verging imbricate system where silicone is absent, and a doubly-verging system where silicone is present, both separated by transfer zones. Additionally, the absence of silicone gives place to fold and thrust belt segments relatively narrower in plan-view and vertically thickened. Both models could be useful to delve into both the deposition of dismantling units and the distribution of along-strike structural differences observed in the Gibraltar Arc fold-and-thrust belt.
Role of nutritional status and inflammation in higher survival of African American and Hispanic hemodialysis patients.

BACKGROUND Observational studies indicate greater survival in African American and Hispanic maintenance hemodialysis patients compared with their non-Hispanic white counterparts, although African Americans have shorter life expectancy than whites in the general population. We hypothesized that this apparent survival advantage is due to a more favorable nutritional/inflammatory profile in minority hemodialysis patients. STUDY DESIGN We examined the association between race/ethnicity and 5-year survival before and after adjustment for case-mix and surrogates of the malnutrition-inflammation complex syndrome (MICS) using Cox regression with or without matched sampling in a large cohort of adult hemodialysis patients. SETTING & PARTICIPANTS 124,029 adult hemodialysis patients, including 16% Hispanics, 49% non-Hispanic whites, and 35% African Americans. PREDICTORS Race/ethnicity before and after adjustment for MICS, including values for body mass index, serum albumin, total iron-binding capacity, ferritin, creatinine, phosphorus, calcium, bicarbonate, white blood cell count, lymphocyte percentage, hemoglobin, and protein intake. OUTCOMES 5-year (July 2001 to June 2006) survival. RESULTS In dialysis patients, blacks and Hispanics had lower mortality overall than non-Hispanic whites after traditional case-mix adjustment. However, after additional control for MICS, Hispanics had mortality similar to non-Hispanic whites, and African Americans had even higher mortality. Unadjusted, case-mix-, and MICS-adjusted HRs for African Americans versus whites were 0.68 (95% CI, 0.66-0.69), 0.89 (95% CI, 0.86-0.91), and 1.06 (95% CI, 1.03-1.09) in the unmatched cohort and, 0.95 (95% CI, 0.90-0.99), 0.89 (95% CI, 0.84-0.94), and 1.16 (95% CI, 1.07-1.26) in the matched cohort, and for Hispanics versus whites, 0.66 (95% CI, 0.64-0.69), 0.84 (95% CI, 0.81-0.87), and 0.97 (95% CI, 0.94-1.00) in the unmatched cohort and 0.89 (95% CI, 0.84-0.95), 0.88 (95% CI, 0.83-0.95), and 0.98 (95% CI, 0.91-1.06) in the matched cohort, respectively. LIMITATIONS Adjustment cannot be made for unmeasured confounders. CONCLUSIONS Survival advantages of African American and Hispanic hemodialysis patients may be related to differences in nutritional and inflammatory status. Further studies are required to explore these differences.
Licensed under Creative Commons Attribution Cc by a Survey on Template Protection Scheme for Multimodal Biometric System

Multi-biometric systems are known to be universal and more accurate in biometric recognition. However, the storage of multiple biometric templates as separate entities pose major threats to user privacy and system security. The development of safe techniques in authentication systems is an important requirement in different fields of our modern interconnected society. Biometrics have long been used for various applications in the areas like access control to facilities and computers, criminal identification, border security, access to nuclear power plant, identity authentication in network environment, airport security, and issue of passports or driver licenses, forensic and medical databases. in now present time there is multimodal biometric is technique which is broadly used for the security in various area. There is various type attack present in biometric system. Many of the attack is applied on the template. In this paper we discuss about the various technique about template protection scheme and present a survey on the template protection scheme multimodal biometric system.
The virtual window simulator

Most virtual reality systems offer the option of viewing the space using a head mounted display or a head coupled display. These can provide a comfortable way of providing a 3D display while detecting head motion and using that to change the viewing position and angle. However, head mounted displays typically have limited resolution, can create neck and eye strain, and can create user disorientation. Head coupled displays, where the display is usually projected onto a screen and the head mount is used for 3D and orientation only, are now a focus of attention in research and in production systems. They are used in, and in fact have spurred the development of, systems like the CAVE, Immersadesk, and IWall to name just three. However, their use is limited by their high cost, fixed nature, and space requirements, and a focus of research is on making head-coupled displays more easily usable and less expensive. The VirtualWindow project is a simulation of a head-coupled display that can be used to develop software for such systems without the expense of owning one, or at least without using the very expensive space. The simulator uses two webcams to perform 3D head tracking rather than instrumenting the user, and provides a set of useful operations that enhance the development and the viewing experience.
Demonstration of a Human €-Globin Gene Silencer With Studies in Transgenic Mice

HE HUMAN p-GLOBIN locus contains five funcT tional genes arranged 5' E-Gy-Ay-6-P 3' in the order of their expression during development. ' Six to 18 kb upstream of the eglobin gene are a series of four DNase I hypersensitive sites that are erythroid specific and developmentally stable, ie, present regardless of which specific globin genes are active. 'z3 Reverse genetics experiments have shown that the region containing these sites (the locus control region [LCR]) confers high-level erythroid-specific expression on cis-linked genes. The LCR effect is dominant; aand @-globin genes, housekeeping (TK) and even nonerythroid genes (THY-l), respond? * The dominant role of LCR raises the question of how the E-, y-, or p-globin genes are silenced at the developmental stages in which these genes are normally quiescent. In the absence of the LCR human yand @-globin genes are properly regulated in transgenic mice, ie, the y gene is expressed in primitive cells while the p gene in definitive erythroid cells. In contrast, transgenic mice containing a human fetal (y) or adult (p) globin gene linked to the LCR express the gene throughout development. '-" Developmental regulation is restored in LCR constructs that contain both the yand p-globin genes, suggesting a reciprocal mechanism for fetal to adult globin gene switching whereby the yand p-globin genes compete for the LCR. ". " In the absence of the LCR, the human e-globin gene is not expressed in transgenic However, when the human e-globin gene is linked to the LCR, it is expressed in a developmentally regulated fashion in transgenic mice, ie, it is expressed in embryonic cells derived from the yolk sac but not in definitive erythroid cells derived from the fetal l i ~ e r . ' ~ * ~ The cellular pattern of LCR-E expression in transgenic mice is the same as that of the native €-globin gene in human, implying that, in contrast to the human yand p-globin genes, linkage to the LCR has not altered the developmental specificity of the human e-globin gene in transgenic mice. The lack of E expression in definitive cells suggests that the eglobin gene contains sufficient information for its own developmental regulation. By transiently transfecting HeLa and K562 cells with mutagenized €-globin constructs, Cao et all4 identified a silencer located between -177 and -392 relative to the E cap site. The effect of the silencer was more pronounced in HeLa cells (10-fold) than in the erythroleukemic cell line K562 (threefold). In this report we examine the role of this element in the autonomous developmental regulation of the human €-globin gene. blasts of the fetal liver and in the red blood cells of adult transgenic mice. These data provide direct in vivo evidence that cis acting silencing elements are involved in the developmental control of the cglobin gene. o 1992 by The American Society of Hematology.
Real Time Enterprises: A Continuous Migration Approach

Current market trends, global competition, and technological innovations are driving enterprises to adopt new approaches to enterprise systems. Real Time Enterprises are organizations that enable automation of processes spanning different systems, media, and enterprise boundaries. Real Time Enterprises provide real time information to employees, customers, suppliers, and partners and implement processes to ensure that all information is current and consistent across all systems, minimizing batch and manual processes related to information. To achieve this, systems for a Real Time Enterprise must be "adaptable" to change and accept "change as the process". This paper provides guidelines, associated ground rules, and an overall approach to transformation to a Real Time Enterprise.
Discrepancy between mRNA and Protein Expression of Neutrophil Gelatinase-Associated Lipocalin in Bronchial Epithelium Induced by Sulfur Mustard

Sulfur mustard (SM) is a potent vesicant that has been employed as a chemical weapon in various conflicts during the 20th century. More recently, mustard was used in the Iraq conflict against Iranian troops and civilians. At the present time there are more than 40.000 people suffering from pulmonary lesions special bronchiolitis obliterans (BOs) due to mustard gas. SM increases the endogenous production of reactive oxygen species (ROS). Neutrophil Gelatinase-associated Lipocalin 2 (Lcn2, NGAL) is a member of the lipocalin superfamily for which a variety of functions such as cellular protection against oxidative stress have been reported. Ten normal and Twenty SM-induced COPD patient individuals were studied. Assessment of NGAL expressions in healthy and the patients endobrinchial biopsies were performed by semiquantitative RT-PCR, real-time RT-PCR, and Immunohistochemistry analysis. While Normal control samples expressed same level of mRNA NGAL, expression level of mRNA-NGAL was upregulated about 1.4- to 9.8-folds compared to normal samples. No significant immunoreactivity was revealed in both samples. As we are aware this is the first report of induction of NGAL in patients exposed to SM. NGAL may play an important role in cellular protection against oxidative stress toxicity induced by mustard gas in airway wall of patients.
Identifying Attractive News Headlines for Social Media

In the past, leading newspaper companies and broadcasters were the sole distributors of news articles, and thus news consumers simply received news articles from those outlets at regular intervals. However, the growth of social media and smart devices led to a considerable change in this traditional relationship between news providers and consumers. Hundreds of thousands of news articles are now distributed on social media, and consumers can access those articles at any time via smart devices. This has meant that news providers are under pressure to find ways of engaging the attention of consumers. This paper provides a novel solution to this problem by identifying attractive headlines as a gateway to news articles. We first perform one of the first investigations of news headlines on a major viral medium. Using our investigation as a basis, we also propose a learning-to-rank method that suggests promising news headlines. Our experiments with 2,000 news articles demonstrate that our proposed method can accurately identify attractive news headlines from the candidates and reveals several promising factors of making news articles go viral.
Responses of the model legume Medicago truncatula to the rhizobial exopolysaccharide succinoglycan

Many species of rhizobial bacteria can invade their plant hosts and induce development of symbiotic nitrogen-fixing nodules only if they are able to produce an acidic exopolysaccharide (EPS) with certain structural and molecular weight characteristics.1–3 Sinorhizobium meliloti that produces the functional form of the exopolysaccharide succinoglycan induces formation of invasion structures called infection threads in the root hair cells of its plant hosts alfalfa and Medicago truncatula. However, S. meliloti mutants that cannot produce succinoglycan are not able to induce infection thread formation, resulting in an early arrest of nodule development and in nitrogen starvation of the plant. Mounting evidence has suggested that succinoglycan acts as a signal to these host plants to permit the entry of S. meliloti. Now, our microarray screen and functional category analysis of differentially-expressed genes show that M. truncatula plants inoculated with wild type S. meliloti receive a signal to increase their translation capacity, alter their metabolic activity and prepare for invasion, while those inoculated with a succinoglycan-deficient mutant do not receive this signal, and also more strongly express plant defense genes.
Does Diversification Destroy Value? Evidence from Industry Shocks

Does corporate diversification reduce shareholder value? Since firms endogenously choose to diversify, exogenous variation in diversification is necessary in order to draw inferences about the causal effect. We examine changes in the within-firm dispersion of industry investment, or diversity. ' We find that exogenous changes in diversity, due to changes in industry investment, are negatively related to firm value. Thus diversification destroys value, consistent with the inefficient internal capital markets hypothesis. This finding is not caused by measurement error. We also find that exogenous changes in industry cash flow diversity are negative related to firm value.
Highly efficient virus-induced gene silencing (VIGS) in California poppy (Eschscholzia californica): an evaluation of VIGS as a strategy to obtain functional data from non-model plants.

BACKGROUND AND AIMS Eschscholzia californica (California poppy) is an emerging model plant for 'evo-devo' studies from the basal eudicot clade of Papaveraceae. California poppy has a relatively small genome, a short life cycle and, most importantly, it is amenable for transformation. However, since this transformation protocol is time consuming, virus-induced gene silencing (VIGS) was evaluated as a fast method to obtain functional data for California poppy genes. METHODS Commercially available California poppy plants were infiltrated with Agrobacterium tumefaciens carrying the tobacco rattle virus plasmids pTRV1 and pTRV2. pTRV2 contained part of the eschscholzia Phytoene Desaturase (EcPDS) gene whose loss of function results in photobleaching of the green parts of the plant and in a lack of floral coloration. The degree and duration of these symptoms was evaluated for vegetative rosettes and plants in flower. KEY RESULTS It is shown that VIGS is able to effectively down-regulate the EcPDS gene in eschscholzia. Various degrees of silencing were observed starting <2 weeks after infiltration with Agrobacterium tumefaciens in 92 % of the plants. Tissue with silencing symptoms also showed complete or strong reduction of EcPDS transcripts. Strong silencing resulted in almost completely white petals, fruits, shoots and leaves. Plants with a strong degree of silencing will eventually die off; however, others are able to produce EcPDS gene product even after a strong initial silencing and will recover. Silencing was found to be not always systemic, but was often restricted to certain organs or parts of organs. CONCLUSIONS VIGS is an effective, fast and transient method to down-regulate gene expression in eschscholzia. It serves well to detect prominent phenotypes which may become obvious even if some target gene transcript remains in the plant tissue. However, subtle phenotypes will be more difficult to detect, as extremely strong silencing effects occur in <10 % of all flowers from infected plants.
The Use of a Capillary Rheometer to Determine the Shear and Extensional Flow Behaviour of Nasal Spray Suspensions

The rheological profiles of four commercial nasal spray suspensions (Beconase, Flixonase, Nasacort and Nasonex) were compared using rotational viscometry. Two of the nasal sprays (Beconase and Nasonex) were further examined in both shear and extension using a capillary rheometer under conditions similar to those experienced at the spray nozzle (i.e. extremely high shear rates with significant stretching or extensional flow).
A Comprehensive Framework for the Development of Dynamic Smart Spaces

The conception of reliable smart spaces requires a suitable and comprehensive framework for their design, implementation, testing, and deployment. Numerous solutions have been proposed to solve different aspects related to smart spaces, but we still lack a concrete framework that provides solutions suitable for the whole development life-cycle. This work aims to fill the gap and proposes a framework that provides: (i) well-defined abstractions for designing smart spaces, (ii) a middleware infrastructure to implement them and plug physical objects, (iii) a semantic layer to support heterogeneous elements, and (iv) plugs to integrate external simulators and be able to always work on "complete'' systems in the different phases of the development.
Sea Ice Meltwater and Circumpolar Deep Water Drive Contrasting Productivity in Three Antarctic Polynyas

In the Southern Ocean, polynyas exhibit enhanced rates of primary productivity and represent large seasonal sinks for atmospheric CO2. Three contrasting east Antarctic polynyas were visited in late December to early January 2017: the Dalton, Mertz, and Ninnis polynyas. In the Mertz and Ninnis polynyas, phytoplankton biomass (average of 322 and 354 mg chlorophyll a (Chl a)/m2, respectively) and net community production (5.3 and 4.6 mol C/m2, respectively) were approximately 3 times those measured in the Dalton polynya (average of 122 mg Chl a/m2 and 1.8 mol C/m2). Phytoplankton communities also differed between the polynyas. Diatoms were thriving in the Mertz and Ninnis polynyas but not in the Dalton polynya, where Phaeocystis antarctica dominated. These strong regional differences were explored using physiological, biological, and physical parameters. The most likely drivers of the observed higher productivity in the Mertz and Ninnis were the relatively shallow inflow of iron‐rich modified Circumpolar Deep Water onto the shelf as well as a very large sea ice meltwater contribution. The productivity contrast between the three polynyas could not be explained by (1) the input of glacial meltwater, (2) the presence of Ice Shelf Water, or (3) stratification of the mixed layer. Our results show that physical drivers regulate the productivity of polynyas, suggesting that the response of biological productivity and carbon export to future change will vary among polynyas.
Magic Pages – Providing Added Value to Electronic Documents

Most electronic documents have a predefined structure, and a visualization of a document is adjusted to this structure. In many cases, however, it is desirable to have different visual representations of the document. This becomes especially important if there is additional information available, for instance, annotations. This paper introduces Magic Pages, a user interface technique that supports different views onto an electronic document. Support in this case means to provide an intuitive way of handling the visualization of textual content as well as additional information. Magic Pages are designed based on the user's experience with the handling of paper documents and treat different views as transparent pages set atop the original text.
Ginseng Berry Extract Promotes Maturation of Mouse Dendritic Cells

Ginseng extract has been shown to possess certain anti-virus, anti-tumor and immune-activating effects. However, the immunostimulatory effect of ginseng berry extract (GB) has been less well characterized. In this study, we investigated the effect of GB on the activation of mouse dendritic cells (DCs) in vitro and in vivo. GB treatment induced up-regulation of co-stimulatory molecules in bone marrow-derived DCs (BMDCs). Interestingly, GB induced a higher degree of co-stimulatory molecule up-regulation than ginseng root extract (GR) at the same concentrations. Moreover, in vivo administration of GB promoted up-regulation of CD86, MHC class I and MHC class II and production of IL-6, IL-12 and TNF-α in spleen DCs. GB also promoted the generation of Th1 and Tc1 cells. Furthermore, Toll like receptor 4 (TLR4) and myeloid differentiation primary response 88 (MyD88) signaling pathway were essential for DC activation induced by GB. In addition, GB strongly prompted the proliferation of ovalbumin (OVA)-specific CD4 and CD8 T cells. Finally, GB induced DC activation in tumor-bearing mice and the combination of OVA and GB treatment inhibited B16-OVA tumor cell growth in C57BL/6 mice. These results demonstrate that GB is a novel tumor therapeutic vaccine adjuvant by promoting DC and T cell activation.