Evaluation of CT Scan and MRI Findings of Pathologically

Abstract Purpose : The aim of this study was to report the main CT scan and MRI findings of gliomas in a group of Iranian patients. Material and Methods : The MRI and CT scan of 96 pathologically proven patients of gliomas were retrospectively evaluated in a period of five years in our university affiliated hospital. We included all cases who had both CT scan and MRI in our study. Results : Among our patients, 60 (62.5%) were male and 36 (37.5%) were female. The mean age of our patients was 41.8±19.3 (7-78). The most common location of tumor was in the parietal lobes (54.2%) followed by the temporal lobes (52.1%), and the frontal lobes (39.6%). The most common subtype was glioblastoma multiform in 42 patients (43.8%). Edema, cystic formation, and hemorrhage were more frequently found in MRI in comparison with CT scan, while CT scan showed calcification better than MRI. Conclusion : In contrast to many other studies, the most common site of gliomas in our patients was parietal lobes. Keywords : glioma, magnetic resonance imaging, computerized tomography References 1.CBTRUS: Central Brain Tumor Registry of the United States. Primary Brain Tumors in the United States: Repory 1995-1999 Years Data Collected. Hinsdale, III; CBTRUS: 2002-2003. 2.Russell D, Rubinstein L. Tumours of central neuroepithelial origin. In Rubinstein LJ, ed. Pathology of tumours of the central nervous system. Baltimore, Md. : Williams & Wilkins, 1989;83-350. 3.Pierallini A, Bonamini M, Pantano P, et al. Radiological assessment of necrosis in glioblastoma: variability and prognostic value. Neuroradiology 1998;40:150–153. 4.Hammoud MA, Sawaya R, Shi W, et al. Prognostic significance of preoperative MRI scans in glioblastoma multiforme. J Neurooncol 1996;27:65–73. 5.Lacroix M, Abi-Said D, Fourney DR, et al. A multivariate analysis of 416 patients with glioblastoma multiforme: prognosis, extent of resection, and survival. J Neurosurg 2001;95:190–198. 6.Nelson JN, Soonmee C. Imaging glioblastoma multiform. The cancer Journal; 2003, 9 (2). 134-143. 7.Kleihues P, Burger PC, Scheithauer BW. Histologic typing of tumours of the central nervous system. 2nd ed. Berlin, Germany: Springer-Verlag, 1993;11-30. 8.Barnard RO, Geddes JF: The incidence of multifocal cerebral gliomas. A histologic study of large hemisphere sections. Cancer 1987; 60(7): 1519-31. 9.Lantos PL, VandenBerg SR, Kleihues P: Tumors of the nervous system. In: Graham DI, Lantos PL, eds. Greenfield's Neuropathology. 6th ed. London, England: Edward Arnold; 1998: 583-879. 10.Burger PC, Green SB: Patient age, histologic features, and length of survival in patients with glioblastoma multiforme. Cancer 1987; 59(9): 1617-25. 11.Tatter BS, Wilson CB, Harsh GR: Neuroepithelial tumors of the adult brain. In: Youman's Neurological Surgery. 4th ed. Philadelphia, Pa: WB Saunders Company; 1996: 2612-2684. 12.Helseth A, Mork SJ: Neoplasms of the central nervous system in Norway. III. Epidemiological characteristics of intracranial gliomas according to histology. APMIS 1989; 97(6): 547-55. 13.Mischel PS, Shai R, Shi T, et al. Identification of molecular subtypes of glioblastoma by gene expression profiling. Oncogene 2003;22:2361–2373. 14.Burger PC, Heinz ER, Shibata T, Kleihues P. Topographic anatomy and CT correlations in the untreated glioblastoma multiforme. J Neurosurg 1988;68:698–704. 15.Rees JH, Smirniotopoulos JG, Jones RV, Wong K. Glioblastoma multiforme: radiologic-pathologic correlation. Radiographics 1996; 16:1413–1438; quiz 1462–1463. 16.Shrieve DC, Alexander E, Black P, et al. Treatment of patients with primary glioblastoma multiforme with standard postoperative radiotherapy and radiosurgical boost: prognostic factors and long-term outcome. J Neurosurg. 1999;90: 72–77. 17.Fleury A, Menegoz F, Grosclaude P, et al. Descriptive epidemiology of cerebral gliomas in France. Cancer. 1997;79: 1195–1202. 18.Muir C, Mack T, Waterhouse J, Powell J, Whelan S. Cancer incidence in five continents. IARC Scientific Publication No. 88. Lyon: International Agency for Research on Cancer,1987. 19.Ferreira NF, Barbosa M, Amaral LL, Mendonca RA, Lima SS. Magnetic resonance imaging in 67 cases of glioblastoma multiforme and occurrence of metastases. Arq Neuropsiquiatr. 2004;62(3A):695-700. 20.Ferreira NF, Barbosa M, Amaral LL, Mendonca RA, Lima SS. Magnetic resonance imaging in 67 cases of glioblastoma multiforme and occurrence of metastases. Arq Neuropsiquiatr. 2004;62(3A):695-700. 21.Larjavaara S, Mantyla R, Salminen T, Haapasalo H, Raitanen J, Jaaskelainen J, Auvinen A. Incidence of gliomas by anatomic location. Neuro-oncol. 2007 23. 22.Atlas SW, Magnetic resonance imaging of the brain and spine, 3rd ed. Philadelphia: Williams and Wilkins, 2002.