Miracle-dz/UniFAR-FTUs huggingface dataset:
Beam Envelope Analysis and Simulation

Forming the charge particle beams with small crosssections and low energies is an actual problem for linac design. That beams are used actively for isotope therapy, ion implantation, etc. Beam emittance is its quality factor, and it should be matched with a facility channel acceptance. The method for beam dynamics analysis at linac is developed in terms of non-coherent particle oscillation study. Nonlinear beam dynamics is investigated by using this method. It is shown that this technique allows one to realize effective beam handling and emittance control. Analytical results obtained are verified by means of numerical simulation. INTRODUCTION One of the most interesting problems of accelerator engineering to date are the design and development of highperformance high-current compact systems for an injection and acceleration of low-velocity heavy-ion beams. This problem as well as others cannot be solved without taking into account problem solution on beam emittance matching with an acceptance of an accelerator channel. Effective acceptance evaluation for the resonance accelerator channel depends on a mathematical model used for describing a beam dynamics. Effective acceptance evaluation of the resonance accelerator channel was performed previously on basis of charged particle beam oscillation as a whole [1] – [4], that is under the assumption of coherent oscillations of individual particles. It is of particular interest to consider a model, which is taking into account non-coherent particle oscillations in the beam, and analyse results based on it. BEAM DYNAMICS It is difficult to analyse a beam dynamics in a high frequency polyharmonic field. Therefore, we will use one of methods of an averaging over a rapid oscillations period, following the formalism presented in [1] – [4]. One first expresses RF field in an axisymmetric periodic resonant structure as Fouriers representation by spatial harmonics of a standing wave assuming that the structure period is a slowly varying function of a longitudinal coordinate z
A new approach to stabilisation of a class of nonlinear systems with an output constraint

ABSTRACT This paper investigates the problem of state-feedback stabilisation for a class of high-order nonlinear systems with an output constraint. A novel tangent-type barrier Lyapunov function is first developed to cope with the output constraint. Then, by introducing the sign function and incorporating the developed tangent-type barrier Lyapunov function, the celebrated adding a power integrator technique is revamped to systematically design a continuous state feedback stabilising controller that prevents violation of the output constraint during operation. The novelty of this paper is the development of an unified design procedure, which can tackle the stabilisation task of the systems with/without the output constraint simultaneously.
Aeroacoustics of NACA 0018 Airfoil with a Cavity

This paper reports a detailed numerical study of the aeroacoustics of a NACA 0018 airfoil with a cavity at zero angle of attack, with chord-based Reynolds and freestream Mach numbers at 2×104 and 0.2, in two dimensions. For an airfoil without a cavity, vortex shedding from the trailing edge and low-frequency wake flapping are found to be the major aeroacoustic processes. The presence of a cavity introduces additional acoustic generation due to cavity oscillation modes but weakens the noise source at the airfoil trailing edge via a jittering of the flow. Three aeroacoustic mechanisms are identified with extensive fast Fourier transform, wavelet, and coherence analyses. The airfoil with cavity effectively increases the lift-to-drag ratio from almost zero (ordinary airfoil) to approximately 5.3. However, it radiates less acoustic power by 1.2 and by 2.6 dB from the airfoil upper and lower surfaces, respectively, even if the acoustic contribution of wake flapping of the ordinary airfoil is excluded. The outco.
An IMM Filter Defined in the Linear-Circular Domain, Application to Maneuver Detection with Heading Only

In this article, we propose a multimodel filter for circular data. The so-called Circular Interacting Multimodel filter is derived in a Bayesian framework with the circular normal von Mises distribution. The aim of the proposed filter is to obtain the same performance in the circular domain as the classical IMM filter in the linear domain. In our approach, the mixing and fusion stages of the Circular Interacting Multimodel filter are, respectively, defined from the a priori and from the a posteriori circular distributions of the state angle knowing the measurements and according to a set of models. We propose in this article a set of circular models that will be used in order to detect the vehicle maneuvers from heading measurements. The Circular Interacting Multimodel filter performances are assessed on synthetic data and we show on real data a vehicle maneuver detection application.
Response surface-based robust parameter design optimization with both qualitative and quantitative variables

ABSTRACT The response surface-based robust parameter design, with its extensive use of optimization techniques and statistical tools, is known as an effective engineering design methodology for improving production processes, when input variables are quantitative on a continuous scale. In many engineering settings, however, there are situations where both qualitative and quantitative variables are considered. In such situations, traditional response surface designs may not be effective. To rectify this problem, this article lays out a foundation by embedding those input variables into a factorial design with pseudo-centre points. A 0–1 mixed-integer nonlinear programming model is then developed and the solutions found using three optimization tools, namely the outer approximation method, the branch-and-bound technique and the hybrid branch-and-cut algorithm, are compared with traditional counterparts. The numerical example shows that the proposed models result in better robust parameter design solutions than the traditional models.
Wave asymptotics at a cosmological time-singularity

We investigate the propagation of the scalar waves in the FLRW universes beginning with a Big Bang and ending with a Big Crunch, a Big Rip, a Big Brake or a Sudden Singularity. We obtain the sharp description of the asymptotics for the solutions of the linear Klein-Gordon equation, and similar results for the semilinear equation with a subcritical exponent. We prove that the number of cosmological particle creations is finite under general assumptions on the initial Big Bang and the final Big Crunch or Big Brake.
Molecular Analysis of Cardiovascular Disease: Some Delay due to Gene-Environment Interactions

The absence of a clear relation between genotype and phenotype has complicated molecular analyses of the susceptibility to common diseases such as cardiovascular disease. Gene-gene and gene-environment interactions may have biased genetic association studies on cardiovascular disease. In the general population, susceptibility to cardiovascular disease is probably the result of many loci with frequently occurring alleles that have relatively small effects. We hypothesize that addition of mortality analyses to genetic association studies may provide important information on the clinical relevance of molecular ﬁndings. We propose to use a parent-offspring model for this purpose: the parents contribute large follow-up and the index cases (offspring) are eliminated from the analyses to remove selection on cardiovascular disease. In particular, indirect estimation of mortality risk has high statistical power and may establish the role of common genetic variation with small effects on cardiovascular disease in the general population. Moreover, the effect of a candidate gene on excess mortality illustrates the quality of such a gene or protein as a novel target for intervention. The results of genetic association studies may have been of little clinical relevance for cardiovascular disease, but we conclude that the methodology still has possibilities for improvements and we propose to use analyses of mortality in a parent-offspring model.
DirtyGrid I: 3D Dust Radiative Transfer Modeling of Spectral Energy Distributions of Dusty Stellar Populations

Understanding the properties of stellar populations and interstellar dust has important implications for galaxy evolution. In normal star-forming galaxies, stars and the interstellar medium dominate the radiation from ultraviolet (UV) to infrared (IR). In particular, interstellar dust absorbs and scatters UV and optical light, re-emitting the absorbed energy in the IR. This is a strongly nonlinear process that makes independent studies of the UV-optical and IR susceptible to large uncertainties and degeneracies. Over the years, UV to IR spectral energy distribution (SED) fitting utilizing varying approximations has revealed important results on the stellar and dust properties of galaxies. Yet the approximations limit the fidelity of the derived properties. There is sufficient computer power now available that it is now possible to remove these approximations and map out of landscape of galaxy SEDs using full dust radiative transfer. This improves upon previous work by directly connecting the UV, optical, and IR through dust grain physics. We present the DirtyGrid, a grid of radiative transfer models of SEDs of dusty stellar populations in galactic environments designed to span the full range of physical parameters of galaxies. Using the stellar and gas radiation input from the stellar population synthesis model PEGASE, our radiative transfer model DIRTY self-consistently computes the UV to far-IR/sub-mm SEDs for each set of parameters in our grid. DIRTY computes the dust absorption, scattering, and emission from the local radiation field and a dust grain model, thereby physically connecting the UV-optical to the IR. We describe the computational method and explain the choices of parameters in DirtyGrid. The computation took millions of CPU hours on supercomputers, and the SEDs produced are an invaluable tool for fitting multi-wavelength data sets. We provide the complete set of SEDs in an online table.
Improvement in accuracy of point seismic sources wavefields numerical modeling

A new scheme of wave fields modelling from point sources in a homogeneous isotropic elastic medium is developed. To set the source the developed technique is based on the use of additional components of the finite-difference grid and the use of all the stress tensor components in the nodes. The results of the scheme employment in the two-dimensional homogeneous isotropic medium are presented; they demonstrate the numerical solutions’ improvement for the source being under consideration in the article.
Multi-wavelength Study of Blazars Using Variability as a Tool

Copyright © The Korean Space Science Society http://janss.kr plSSN: 2093-5587 elSSN: 2093-1409 Received 23 MAY 2016 Revised 2 JUN 2016 Accepted 3 JUN 2016 †Corresponding Author E-mail: baliyan@prl.res.in, ORCID: 0000-0003-0180-8231 Tel: +91-79-2631-4509, Fax: +91-79-2970-3573 This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http:// creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. Research Paper J. Astron. Space Sci. 33(3), 177-183 (2016) http://dx.doi. org/10.5140/JASS.2016. 33.3. 177
Two cartesian products which are euclidean spaces

© Bulletin de la S. M. F. , 1960, tous droits réservés. L’accès aux archives de la revue « Bulletin de la S. M. F. » (http: //smf.emath.fr/Publications/Bulletin/Presentation.html) implique l’accord avec les conditions générales d’utilisation (http://www.numdam.org/ conditions). Toute utilisation commerciale ou impression systématique est constitutive d’une infraction pénale. Toute copie ou impression de ce fichier doit contenir la présente mention de copyright.
Likelihood-based methods for analysis of copy number variation using next generation sequencing data.

LIKELIHOOD-BASED METHODS FOR ANALYSIS OF COPY NUMBER VARIATION USING NEXT GENERATION SEQUENCING DATA Udika Iroshini Bandara July 21, 2017 A Copy Number Variation (CNV) detection problem is considered using Circular Binary Segmentation (CBS) procedures, including newly developed procedures based on likelihood ratio tests with the parametric bootstrap for models based on discrete distributions for count data (Poisson and negative binomial) and a widely-used DNAcopy package. Results from the literature concerning maximum likelihood estimation for the negative binomial distribution are reviewed. The Newton-Raphson method is used to find the root of the derivative of the profile log likelihood function when applicable, and it is proven that this method converges to the true MLE, if the starting point for the Newton-Raphson is selected appropriately and the MLE exists. Simulation studies are conducted to examine the performance of the CBS procedures under various scenarios. Also, the procedures are applied to a real data example based on the baboon endogenous viral genome.
Dynamic acousto-elastic response of single fatigue cracks with different microstructural features: An experimental investigation

Nonlinearity of damaged materials is often assumed to be correlated with the cumulative length of micro-cracks discounting the influence of crack width and roughness. To investigate the influence of microstructural features of realistic cracks on the nonlinear elastic properties, Dynamic Acousto-Elastic Testing (DAET) is performed on two aluminum alloy samples (30 × 40 × 170 mm3) with a single fatigue-crack. The cracks on the two samples are of similar length but have dissimilar microstructural features due to the different stress intensity factors used during the fatigue tests. DAET is carried out with a surface wave probe to measure the near-surface nonlinearity at a number of locations along each crack. The geometric features of the cracks, including crack width and roughness, are extracted from a series of scanning electron microscope images. DAET results demonstrate that nonlinearity varies along the crack; both samples exhibit greater nonlinearity near the notch, where the crack is wider than near the crack tip. However, the nonlinearity parameters obtained from the sample with a smoother crack are one order of magnitude larger than those of the sample with a relatively rough crack. In addition, the nonlinearity signatures of the two cracks exhibit very different tension/compression asymmetry. This study provides valuable data that not only directly correlates the nonlinear ultrasonic signatures and crack interface features but also illuminates the micro-mechanisms and origins of the measured nonlinearities.Nonlinearity of damaged materials is often assumed to be correlated with the cumulative length of micro-cracks discounting the influence of crack width and roughness. To investigate the influence of microstructural features of realistic cracks on the nonlinear elastic properties, Dynamic Acousto-Elastic Testing (DAET) is performed on two aluminum alloy samples (30 × 40 × 170 mm3) with a single fatigue-crack. The cracks on the two samples are of similar length but have dissimilar microstructural features due to the different stress intensity factors used during the fatigue tests. DAET is carried out with a surface wave probe to measure the near-surface nonlinearity at a number of locations along each crack. The geometric features of the cracks, including crack width and roughness, are extracted from a series of scanning electron microscope images. DAET results demonstrate that nonlinearity varies along the crack; both samples exhibit greater nonlinearity near the notch, where the crack is wider than near t.
Dynamic Topic Detection and Tracking using Non-Negative Matrix Factorization

Most textual data contains a time component that is highly relevant for many economic decision processes. Especially in large document sets and high-frequency document streams it is impossible for humans to gain an overview of the topics in all texts by reading them. Although algorithms such as non-negative matrix factorization (NMF) or latent Dirichlet allocation (LDA) have been applied successfully for static topic extraction in the past years, only few approaches exist for topic analysis on dynamically changing data. We present a hybrid NMF approach combined with hierarchical clustering to detect and track emerging topics in streaming text data. The performance of the algorithm is demonstrated both on simulated and on real-world news text data.
Fault-tolerant sensor reconciliation schemes based on unknown input observers

ABSTRACT This paper proposes two fault-tolerant sensor reconciliation design methods for over-sensed plants. The aim of the reconciliator is to detect the presence of faults on the existing physical sensors and hide the corrupted measurements in the generation of a virtual output, which one would like to be generated in a reliable way in spite of fault occurrences and hence trustfully usable for control purposes. The sensor faults here considered are limited to variations of both sensor gain and offset values. The proposed approach envisages the use of an unknown input observers coupled with an ‘ad-hoc’ parameters estimator used to estimate online the sensor effectiveness matrix at each time instant. In the paper, two design methodologies are described, based one on the linear parameter varying polytopic formulation and the other on the linear fractional transformation paradigm. All main properties of the considered schemes are investigated and rigorously proved.
The Consequences of Varying Measurement Occasions in Discrete-Time Survival Analysis

In a discrete-time survival model the occurrence of some event is measured by the end of each time interval. In practice it is not always possible to measure all subjects at the same point in time. In this study the consequences of varying measurement occasions are investigated by means of a simulation study and the analysis of data from an empirical study. The results of the simulation study suggest that the effects of varying measurement occasions are negligible, at least for the scenarios that were covered in the simulation. The empirical example shows varying measurement occasions have minor effects on parameter estimates, standard errors, and significance levels.
Stellenwert der Defibrillatortherapie in der Sekundär- und Primärprophylaxe des plötzlichen Herztodes

Die Implantation eines Defibrillators ist Therapie der ersten Wahl bei Patienten, die eine Epi-sode von Kammerflimmern außerhalb eines akuten Herzinfarktes überlebt haben. Bei vielen Patienten besteht aber auch schon vorher eine Indikation, insbesondere bei Patienten, die nach einem Herzinfarkt oder bei einer Herzinsuffizienz eine stark eingeschränkte Auswurffraktion haben. Eine konsequente Umsetzung bestehender Leitlinien in diesem Bereich ermöglicht eine signifikante Verbesserung der Prognose unserer Patienten und ist trotz des relativ hohen Ag-gregatpreises kosteneffizienter als viele andere Therapien in der modernen Medizin
Controlling terahertz spectrum in asymmetric air plasmas: the role of GDD and phase

Short THz pulses can be generated by focusing an ultrashort laser pulse and its second harmonic simultaneously in ambient air and generating plasma. The process is efficient in the right circumstances, but sensitive to the relative phase between the two pulses and the initial group delay dispersion (GDD) of the fundamental beam. Previously it was found that zero initial dispersion and π/2 relative phase is the optimal for most cases. In this work, the connection between the nonlinear crystal thickness and the spectral phase properties has been also studied for THz generation. It has been found there are conditions where the THz spectral bandwidth can by continuously tune in the function of the GDD value. It has been also found that the optimal crystal thickness strongly varies with the laser energy, hence with the peak intensity.
The right top coupling in the aligned two-Higgs-doublet model

We compute the right top quark coupling in the aligned two-Higgs-doublet model. In the Standard Model the real part of this coupling is dominated by QCD-gluon-exchange diagram, but the imaginary part, instead, is purely electroweak at one loop. Within this model we show that values for the imaginary part of the coupling up to one order of magnitude larger than the electroweak prediction can be obtained. For the real part of the electroweak contribution we find that it can be up to three orders of magnitude larger than the standard model one. We also present detailed results of the one loop analytical computation.
0 0 VI % 0 Yeast Sequencing Reports Fifteen Open Reading Frames in a 30 % kb Region of the Right Arm of Chromosome VI from Saccharomyces

Division of Human Genome Research and Gene Bank, Tsukuba Lije Science Center, The Institute of Physical and Chemical Research (RIKEN), 3-1-1 Koyadai, Tsukuba, Ibaraki 305, Japan, SBioscience Research Laboratory, Fujiya Co., 228 Soya, Hatano, Kanagawa 257, Japan, $Graduate School of Science and Engineering, Saitumu University, 255 Shimo-okubo, Urawa, Saitama 338, Japan, TBiodesign Research Group and #Cellular Physiology Laboratory, The Institute of Physical and Chemical Research (RIKEN), 2-1 Hirosawu, Wuko, Saitama 351-01, Japan
0 t0 IX 0 Yeast Sequencing Reports 00 . 00 GUT 2 , a Gene for Dehydrogenase of Mitochondrial Saccharomy ces Glycerol 3-Phosphate cerevisiae

A gut2 mutant of Saccharomyces cerevisiae is deficient in the mitochondrial glycerol 3-phosphate dehydrogenase and hence cannot utilize glycerol. Upon transformation of a gut2 mutant strain with a low-copy yeast genomic library, hybrid plasmids were isolated which complemented the gut2 mutation. The nucleotide sequence of a 3.2 kb PstI-XhoI fragment complementing a gut2 mutant strain is presented. The fragment reveals an open reading frame (ORF) encoding a polypeptide with a predicted molecular weight of 68.8 kDa. Disruption of the ORF leads to a glycerol non-utilizing phenotype. A putative flavin-binding domain, located at the amino terminus, was identified by comparison with the amino acid sequences of other flavoproteins. The cloned gene has been mapped both physically and genetically to the left arm of chromosome IX, where the original gut2 mutation also maps. We conclude that the presented ORF is the GUT2 gene and propose that it is the structural gene for the mitochondrial glycerol 3-phosphate dehydrogenase.