Miracle-dz/UniFAR-FTUs huggingface dataset:
Iterative Reduction of Out-of-Band Power and Peak-to-Average Power Ratio for Non-Contiguous OFDM Systems Based on POCS

SUMMARY Non-contiguous orthogonal frequency-division multiplexing (OFDM) is a promising technique for cognitive radio systems. The secondary users transmit on the selected subcarriers to avoid the frequencies being used by the primary users. However, the out-of-band power (OBP) of the OFDM-modulated tones induces interference to the primary users. Another major drawback of OFDM-based system is their high peak-to-average power ratio (PAPR). In this paper, algorithms are proposed to jointly reduce the OBP and the PAPR for non-contiguous OFDM based on the method of alternating projections onto convex sets. Several OFDM subcarriers are selected to accommodate the adjusting weights for OBP and PAPR reduction. The frequency-domain OFDM symbol is projected onto two convex sets that are deﬁned according to the OBP requirements and the PAPR limits. Each projection iteration solves a convex optimization problem. The projection onto the set constrained by the OBP requirement can be calculated using an iterative algorithm which has low computational complexity. Simulation results show good performance of joint reduction of the OBP and the PAPR. The proposed algorithms converge quickly in a few iterations.
A comparison of goal attainment scaling and the Canadian occupational performance measure for paediatric rehabilitation research

Purpose: To investigate the relative utility of Canadian Occupational Performance Measure (COPM) (adapted for children) and Goal Attainment Scaling (GAS) as outcome measures for paediatric rehabilitation. Methods: A two-group pre–post design investigated the impact of a 3-month programme. Forty-one children with spastic hemiplegic cerebral palsy (mean 3.9 years; GMPM level 1; 21 boys, 10 girls) were randomized to occupational therapy only and occupational therapy plus one Botulinum Toxin A injection. The latter was considered a ‘proven’ intervention for the purpose of this instrumentation study. Intervention impact was investigated using GAS and COPM. Instrument sensitivity, convergent validity, goal/problem profiles and administration were evaluated. Results: Both instruments were sensitive to within group change and detected significant between group change. Likert scale coding for GAS scores was more sensitive than the traditional weighted GAS or COPM. Different constructs were measured by each instrument. COPM was more time efficient in training, development and administration. Conclusion: Study aim, logistic and resource factors should guide the choice of COPM and/or GAS instruments as both are sensitive to change with a proven intervention and both evaluate different constructs.
TINTIN: Exploiting Target Features for Signaling Network Similarity Computation and Ranking

Network similarity ranking attempts to rank a given set of networks based on its "similarity" to a reference network. State-of-the-art approaches tend to be general in the sense that they can be applied to networks in a variety of domains. Consequently, they are not designed to exploit domain-specific knowledge to find similar networks although such knowledge may yield interesting insights that are unique to specific problems, paving the way to solutions that are more effective. We propose Tintin which uses a novel target feature-based network similarity distance for ranking similar signaling networks. In contrast to state-of-the-art network similarity techniques, Tintin considers both topological and dynamic features in order to compute network similarity. Our empirical study on signaling networks from BioModels with real-world curated outcomes reveals that Tintin ranking is different from state-of-the-art approaches.
Molecular characterization of the Jatropha curcas JcR1MYB1 gene encoding a putative R1-MYB transcription factor

The cDNA encoding the R1-MYB transcription factor, designated as JcR1MYB1, was isolated from Jatropha curcas using rapid amplification of cDNA ends. JcR1MYB1 contains a 951 bp open reading frame that encodes 316 amino acids. The deduced JcR1MYB1 protein was predicted to possess the conserved, 56-amino acid-long DNA-binding domain, which consists of a single helix-turn-helix module and usually occurs in R1-MYBs. JcR1MYB1 is a member of the R1-MYB transcription factor subfamily. A subcellular localization study confirmed the nuclear localization of JcR1MYB1. Expression analysis showed that JcR1MYB1 transcripts accumulated in various examined tissues, with high expression levels in the root and low levels in the stem. JcR1MYB1 transcription was up-regulated by polyethylene glycol, NaCl, and cold treatments, as well as by abscisic acid, jasmonic acid, and ethylene treatment. Analysis of transgenic tobacco plants over-expressing JcR1MYB1 indicates an inportant function for this gene in salt stress.
Physical Activity During Recess Outdoors and Indoors Among Urban Public School Students, St. Louis, Missouri, 2010–2011

We measured the quantity and intensity of physical activity in 106 urban public school students during recess outdoors, recess indoors in the gym, and recess indoors in the classroom. Students in grades 2 through 5 wore accelerometer pedometers for an average of 6.2 (standard deviation [SD], 1.4) recess periods over 8 weeks; a subsample of 26 also wore heart rate monitors. We determined, on the basis of 655 recess observations, that outdoor recess enabled more total steps per recess period (P < .0001), more steps in moderate-to-vigorous physical activity (P < .0001), and higher heart rates than recess in the gym or classroom. To maximize physical activity quantity and intensity, school policies should promote outdoor recess.
SyntHorus: Highly efficient automatic synthesis from PSL to HDL

We propose a linear complexity approach to achieve automatic synthesis of designs from temporal specifications. Each property is turned into a component combining monitor and generator features: the extended-generator. We connect them with specific components to obtain a design that is correct by construction. It shortens the design flow by removing implementation and functional verification steps. Our approach synthesizes circuits specified by hundreds of temporal properties in a few seconds. Complex examples (i.e. CONMAX-IP and GenBuf) show the efficiency of the approach.
"Gluten-sensitive diarrhea without evidence of celiac disease".

Abstract Eight adult female patients suffering from abdominal pain and chronic diarrhea which was often incapacitating and frequently nocturnal, had dramatic relief on a gluten-free diet and return of symptoms after gluten challenge. Previous nonspecific measures and a milk-free diet were ineffective. Multiple jejunal biopsies showed minor, but significant changes in cellularity which returned to normal on the gluten-free diet. Apart from a slight increase in jejunal cellularity, no immunological abnormalities were found after gluten challenge. Steatorrhea or other biochemical defects, common in celiac disease, were not found. It was concluded that these patients had a gluten-sensitive diarrhea, but had no evidence of celiac disease.
Human NK Cell Subsets Redistribution in Pathological Conditions: A Role for CCR7 Receptor

Innate and adaptive immunity has evolved complex molecular mechanisms regulating immune cell migration to facilitate the dynamic cellular interactions required for its function involving the chemokines and their receptors. One important chemokine receptor in the immune system is represented by CCR7. Together with its ligands CCL19 and CCL21, this chemokine receptor controls different arrays of migratory events, both in innate and adaptive immunity, including homing of CD56bright NK cells, T cells, and DCs to lymphoid compartments, where T cell priming occurs. Only recently, a key role for CCR7 in promoting CD56dim NK cell migration toward lymphoid tissues has been described. Remarkably, this event can influence the shaping and polarization of adaptive T cell responses. In this review, we describe recent progress in understanding the mechanisms and the site where CD56dim KIR+ NK cells can acquire the capability to migrate toward lymph nodes. The emerging significance of this event in clinical transplantation is also discussed.
Delay-Dependent Stability Analysis for Switched Neural Networks With Time-Varying Delay

In this paper, the problem of stability analysis is investigated for switched neural networks with time-varying delay using linear matrix inequality (LMI) approach. By taking advantage of the average dwell time method, two sufficient conditions are developed to ensure the global exponential stability of the considered neural networks, which are delay-dependent and formulated by LMIs. The state decay estimate is explicitly given. Numerical examples are provided to demonstrate the effectiveness and feasibility of the proposed techniques.
Port assignment for interconnect reduction in high-level synthesis

This paper focuses on the Port Assignment Problem for Binary Commutative Operators (PAP-BCO) in high-level synthesis. Given a binding of operations and variables, the PAP-BCO pursues to build the connections of registers to functional units with an objective of minimizing the number of interconnections. In this paper, we formulate the PAP-BCO as a vertex partitioning problem on a graph, and propose an exact Integer Linear Programming (ILP) based method and a fast iterative method based on elementary transformations of spanning tree to solve it. Experimental results show that the fast iterative algorithm can get the optimum solutions in 97% runs. At the same time, the running time is only tens of milliseconds for the maximum test case with 64 registers and 140 operations, on which the ILP based method ran out of time.
Computational linguistic support for legal ontology construction

The potential of knowledge-based technological support for work in the legal domain has become widely recognized in recent time. This paper argues for an approach that is meant to complement existing work on top-level, statute-based ontologies for the law by extracting conceptual knowledge from verdict texts. Starting from a corpus-based survey on the definition and modification of concepts in German court verdicts we are currently working out a detailed description of the linguistic structures and semantic mechanisms involved. Based on this we want to develop tools that automatically recognize and process portions of verdicts that contain definitions. The resulting system will support the corpus-based extension of (hand-made) top-level legal ontologies and the update of legal terminological knowledge bases with regard to new jurisdiction. The research described in the paper is conducted at the Saarbrücken computational linguistics (CL) group within the project CORTE (computational linguistic methods for legal terminology).
Factors Associated with Anti-Tuberculosis Medication Adverse Effects: A Case-Control Study in Lima, Peru

Background Long-term exposure to anti-tuberculosis medication increases risk of adverse drug reactions and toxicity. The objective of this investigation was to determine factors associated with anti-tuberculosis adverse drug reactions in Lima, Peru, with special emphasis on MDR-TB medication, HIV infection, diabetes, age and tobacco use. Methodology and Results A case-control study was performed using information from Peruvian TB Programme. A case was defined as having reported an anti-TB adverse drug reaction during 2005–2010 with appropriate notification on clinical records. Controls were defined as not having reported a side effect, receiving anti-TB therapy during the same time that the case had appeared. Crude, and age- and sex-adjusted models were calculated using odds ratios (OR) and 95% confidence intervals (95%CI). A multivariable model was created to look for independent factors associated with side effect from anti-TB therapy. A total of 720 patients (144 cases and 576 controls) were analyzed. In our multivariable model, age, especially those over 40 years (OR = 3.93; 95%CI: 1.65–9.35), overweight/obesity (OR = 2.13; 95%CI: 1.17–3.89), anemia (OR = 2.10; IC95%: 1.13–3.92), MDR-TB medication (OR = 11.1; 95%CI: 6.29–19.6), and smoking (OR = 2.00; 95%CI: 1.03–3.87) were independently associated with adverse drug reactions. Conclusions Old age, anemia, MDR-TB medication, overweight/obesity status, and smoking history are independent risk factors associated with anti-tuberculosis adverse drug reactions. Patients with these risk factors should be monitored during the anti-TB therapy. A comprehensive clinical history and additional medical exams, including hematocrit and HIV-ELISA, might be useful to identify these patients.
ADAPTIVE GOVERNANCE OF SOCIAL-ECOLOGICAL SYSTEMS

▪ Abstract We explore the social dimension that enables adaptive ecosystem-based management. The review concentrates on experiences of adaptive governance of social-ecological systems during periods of abrupt change (crisis) and investigates social sources of renewal and reorganization. Such governance connects individuals, organizations, agencies, and institutions at multiple organizational levels. Key persons provide leadership, trust, vision, meaning, and they help transform management organizations toward a learning environment. Adaptive governance systems often self-organize as social networks with teams and actor groups that draw on various knowledge systems and experiences for the development of a common understanding and policies. The emergence of “bridging organizations” seem to lower the costs of collaboration and conflict resolution, and enabling legislation and governmental policies can support self-organization while framing creativity for adaptive comanagement efforts. A resilient social-eco.
Cluster Synchronization for Linearly Coupled Complex Networks with Identical and Nonidentical Nodes

The cluster synchronization of linearly coupled complex networks with identical and nonidentical nodes is studied. Without assuming symmetry, we proved that these linearly coupled complex networks could achieve cluster synchronization under certain pinning control schemes. Sufficient conditions guaranteeing cluster synchronization for any initial values are derived by using Lyapunov function methods. Moreover, the adaptive feedback algorithms are proposed to adjust the control strength. Several numerical examples are given to illustrate our theoretical results.
Understanding Epidemic Outbreaks through Cutting-edge Computational Tools.

that have useful functions. Of course, in a newly derived symbiont, there are many genes that no longer provide useful functions, so the pressure to avoid those errors is reduced. Furthermore, the authors propose that it may be advantageous to erode those genes to relieve the burden of their maintenance and operation. The authors conclude “gene inactivation and deletion has the potential to increase fitness by streamlining the gene inventory and removing functions that have a high cost to benefit ratio. ” This study provides important insights into mechanisms that shape genome evolution upon transition to a hostdependent lifestyle and the potential benefits of this type of “mutator” phenotype in nascent symbionts.
Cardioembolism and Involvement of the Insular Cortex in Patients with Ischemic Stroke

Background To evaluate whether topographical characteristics of insular involvement in ischemic stroke are associated with cardioembolism. Methods and Findings A consecutive series of patients hospitalized for ischemic stroke within 7 days of symptom onset were identified. Based on diffusion-weighted imaging, we included those who had ischemic lesions in the middle cerebral artery (MCA) territory. Each patient was assigned to one of two groups based on the presence or absence of insular involvement. The primary outcome was the frequency of cardioembolism, which was compared based on insular involvement. Of 1,311 patients with ischemic stroke in the MCA territory, 112 had insular involvement (8.5%). The frequency of cardioembolism in patients with insular involvement (52.7%) was significantly higher than that in patients without insular involvement (30.4%, P < 0.001). Although insular involvement was associated with a severe baseline National Institutes of Health Stroke Scale score (13 vs. 4), it did not independently affect the 3-month functional outcome. Conclusions In cases of stroke in the MCA territory, involvement of the insular cortex may be associated with a risk of cardioembolism.
A Single Case Research Study on the Short Term, In- home Use of Modified Power Ride-On Toys for a Pre- school Aged Child with Cerebral Palsy

This research study (A-B-C design) measured the effects of use of two modified power ride-on toys (PROTs) by a three year old child with cerebral palsy (CP). The first PROT had adaptive seating and minor control interface modifications (PROT-S), and the second had adaptive seating and drive system/control interface modifications (PROT-SD). The A phase (five weeks) occurred before she received a PROT. She used the PROT-S in phase B for five weeks, and then switched to the PROT-SD in phase C (also five weeks). Her functional mobility, driving skills, upper extremity skills, and social function skills increased throughout the study. Between-phase analysis revealed the child scored higher and improved faster on her driving skills, and also on her ability to perform functional mobility skills and achieve parent-set goals while using the PROT-SD. This study provides preliminary evidence that using modified PROTs may have positive effects on young children with CP.
Localization in 3D environments using differential, evolution

It is necessary to determine the robot's pose to localize a mobile robot in a known environment. If there is no information about the initial location, we are talking about global localization. In our previous work we solved this problem in a two-dimensional environment with an algorithm known as Evolutive Localization Filter (ELF). Based on evolutionary computation concepts, the proposed algorithm searches stochastically along the state space for the robot's best pose estimate. In this paper we have improved our method designing an algorithm with new features, called ELF-3D, that uses three-dimensional sensorial information. The resulting global localization module has been tested in a simulated indoor environment. The most important improvement obtained is the accuracy of the method, allowing to apply it in manipulation tasks.
Sherlock: a Semi-Automatic Quiz Generation System using Linked Data

This paper presents Sherlock, a semi-automatic quiz generation system for educational purposes. By exploiting semantic and machine learning technologies, Sherlock not only offers a generic framework for domain independent quiz generation, but also provides a mechanism for automatically controlling the difficulty level of the generated quizzes. We evaluate the effectiveness of the system based on three real-world datasets.
Shape from regularities for interactive 3D reconstruction of piecewise planar objects from single images

3D object reconstruction from single 2D images has many applications in multimedia. This paper proposes an approach based on image regularities such as connectivity, parallelism, and orthogonality possessed by the objects with simple user interactions. It is assumed that the objects are piecewise planar. By representing the 3D objects as a shape vector consisting of the normals of the faces of the objects, we impose geometric constraints on this shape vector using the regularities of the objects. We derive a system of equations in terms of the shape vector and the focal length, which we can solve for the shape vector optimally. Experimental results on real images are shown to demonstrate the effectiveness of this method.
p107 acts as a tumor suppressor in pRb‐deficient epidermis

The specific deletion of Rb gene in epidermis leads to altered proliferation and differentiation, but not to the development of spontaneous tumors. Our previous data have demonstrated the existence of a functional compensation of Rb loss by Rbl1 (p107) in as the phenotypic differences with respect to controls are intensified. However, the possible evolution of this aggravated phenotype, in particular in relationship with tumorigenesis, has not been evaluated due to the premature death of the double deficient mice. We have now investigated whether p107 can also act as a tumor suppressor in pRb‐deficient epidermis using different experimental approaches. We found spontaneous tumor development in doubly‐deficient skin grafts. Moreover, Rb‐deficient keratinocytes are susceptible to Ha‐ras‐induced transformation, and this susceptibility is enhanced by p107 loss. Further functional analyses, including microarray gene expression profiling, indicated that the loss of p107, in the absence of pRb, produces the reduction of p53‐dependent pro‐apoptotic signals. Overall, our data demonstrate that p107 behaves as a tumor suppressor in epidermis in the absence of pRb and suggest novel tumor‐suppressive roles for p107 in the context of functional p53 and activated Ras. © 2007 Wiley‐Liss, Inc.
The Morphology and Behavior of Living Exoerythrocytic Stages of Plasmodium gallinaceum and P. fallax and Their Host Cells

The morphology and behavior of living exoerythrocytic stages of Plasmodium gallinaceum and P. fallax were studied by the use of tissue cultures, phase contrast microscopy, and time-lapse cinephotomicrography. The morphology of exoerythrocytic stages of these two species was essentially that previously observed in fixed, stained material, with the following exceptions: (1) the presence of a filament on one end of the merozoite, (2) the absence of clefts in the cytoplasm of the large schizonts, and (3) the absence of a vacuole-like space around the parasite. The following behavior was observed either directly or in time-lapse sequences: (1) emergence of merozoites from mature schizonts, (2) progressive motility of free merozoites, (3) entry of merozoites, both actively and passively, into host cells, (4) nuclear division in the parasite, (5) the various stages of schizogony, including final production of merozoites, (6) massive infection of host cells, and (7) phagocytosis of merozoites and attempted phagocytosis of mature schizonts by macrophages. Exoerythrocytic stages of P. fallax differed from those of P. gallinaceum in that the merozoites of the former were (1) somewhat more curved in shape and (2) present in fewer numbers in mature schizonts. The use of tissue culture, phase contrast microscopy, and time-lapse cinephotomicrography promises to solve many of the remaining problems concerning exoerythrocytic stages of malarial parasites and their interrelationships with host cells.
Constructing hysteretic memory in neural networks

Hysteresis is a unique type of dynamic, which contains an important property, rate-independent memory. In addition to other memory-related studies such as time delay neural networks, recurrent networks, and reinforcement learning, rate-independent memory deserves further attention owing to its potential applications. In this paper, we attempt to define hysteretic memory (rate independent memory) and examine whether or not it could be modeled in neural networks. Our analysis results demonstrate that other memory-related mechanisms are not hysteresis systems. A novel neural cell, referred to herein as the propulsive neural unit, is then proposed. The proposed cell is based on a notion related the submemory pool, which accumulates the stimulus and ultimately assists neural networks to achieve model hysteresis. In addition to training by backpropagation, a combination of such cells can simulate given hysteresis trajectories.