Miracle-dz/UniFAR-FTUs huggingface dataset:
Heart rate calculation from ensemble brain wave using wavelet and Teager-Kaiser energy operator

Electroencephalogram (EEG) signal artifacts are caused by various factors, such as, Electro-oculogram (EOG), Electromyogram (EMG), Electrocardiogram (ECG), movement artifact and line interference. The relatively high electrical energy cardiac activity causes EEG artifacts. In EEG signal processing the general approach is to remove the ECG signal. In this paper, we introduce an automated method to extract the ECG signal from EEG using wavelet and Teager-Kaiser energy operator for R-peak enhancement and detection. From the detected R-peaks the heart rate (HR) is calculated for clinical diagnosis. To check the efficiency of our method, we compare the HR calculated from ECG signal recorded in synchronous with EEG. The proposed method yields a mean error of 1.4% for the heart rate and 1.7% for mean R-R interval. The result illustrates that, proposed method can be used for ECG extraction from single channel EEG and used in clinical diagnosis like estimation for stress analysis, fatigue, and sleep stages classification studies as a multi-model system. In addition, this method eliminates the dependence of additional synchronous ECG in extraction of ECG from EEG signal process.
Hormones and the Human Family

HORMONES AND NEUROTRANSMITTERS help shape important aspects of our lives, including growth, differentiation, sexuality, physiology, emotion, and cognition. From romantic thoughts to jealous rage, from the release of gametes to lactation and parent-offspring bonding, the extraordinary molecules produced and released by tiny and otherwise seemingly insignificant cells and glands orchestrate our reproductive strategies. A key research objective is to understand the evolutionary functions of this chemical language. Endocrine and neuroendocrine systems may be viewed as complex sets of mechanisms designed by natural selection to communicate information among cells and tissues. This chapter focuses on an area of particular importance for evolutionary psychology: the behavioral endocrinology of the human family. Steroid and peptide hormones, associated neurotransmitters, and other chemical messengers guide mating and parental behaviors of mammals in many important ways (Curtis & Wang, 2003; Rosenblatt, 2003; Young & Insel, 2002). Cross-species comparisons among primates require careful analysis (Bercovitch & Ziegler, 2002) because of the apparent rapid evolutionary changes in patterns of reproductive behaviors and increased phenotypic flexibility involving intricate mental processes. Homo sapiens presents special problems in these regards (Fisher, 2004; Maestripieri, 1999; Marler, Bester-Meredith, & Trainor, 2003; Wynne-Edwards, 2001, 2003). Here we first provide a theoretical scenario for the evolution of human patterns of mating and parenting behaviors. We test our model by examining the phylogenetic trajectories of associated traits such as sexual dimorphism and life history stages from the hominin fossil record. We then turn to a description and functional analysis of the endocrine mechanisms that may influence these remarkable reproductive behavioral characteristics of our species.
Regulated tissue- and cell-specific expression of the human renin gene in transgenic mice.

Transgenic mice containing the human renin gene were constructed with the aim of examining the tissue- and cell-specific expression of human renin. The human renin transgene used consisted of a genomic sequence extending approximately 900 bp upstream and 400 bp downstream of the coding region and included all exon and intron sequences. Two assays were developed to differentiate human renin transcripts from endogenous mouse renin transcripts at the whole-tissue level. High level human renin expression was evident in the kidney, adrenal gland, ovary, testis, lung, and adipose tissue of all four transgenic lines examined. Human renin mRNA could also be detected at lower levels in the submandibular gland and heart of two different individual lines. No expression was evident in the liver or brain of any line tested. In situ hybridization revealed the human renin mRNA to be localized and exquisitely restricted to renal juxtaglomerular cells. Treatment of transgenic mice with captopril resulted in an increase in the accumulation of renal renin mRNAs derived from both the mouse and human renin genes. Plasma renin activity assays using synthetic human renin substrate clearly demonstrated the elaboration of active human renin into the systemic circulation of transgenic mice. These data strongly suggest that the human renin transgene exhibits both tissue- and cell-specific expression in transgenic mice. Its expression is entrained to the same regulatory signals as the endogenous renin gene in kidney, and active human renin is released into the plasma of the transgenic mice. (ABSTRACT TRUNCATED AT 250 WORDS)
Draft Genome Sequence of a Multi-Metal Resistant Bacterium Pseudomonas putida ATH-43 Isolated from Greenwich Island, Antarctica

At low concentrations, heavy metals and metalloids are highly toxic for most microorganisms (Lemire et al., 2013). Over evolution, bacteria have developed several molecular mechanisms in order to cope with heavy metal/metalloid toxicity (Nies, 2000; Lemire et al., 2013). Pseudomonas putida belongs to a group of versatile microorganisms capable to thrive in diverse hostile environments, including multi-metal polluted cold sites (Canovas et al., 2003; Zhang et al., 2012; Moreno and Rojo, 2013). Members of P. putida are largely known for their ability to colonize different kinds of environments and to degrade a vast diversity of toxic organic compounds (Wu et al., 2011). In this context, P. putida ATH-43 was isolated from soil sediments at the “Prat” Chilean military base located in Greenwich Island, Antarctica, and was recognized as a mercury/tellurite resistant bacterium (Rodriguez-Rojas et al., 2015). Interestingly, this strain shows tellurite resistance only when grown in the presence of mercury, suggesting a cross-resistance mechanism. Further experimental evidence revealed that P. putida ATH-43 is highly resistant to other toxicants such as Cd2+, Cu2+, CrO42−, and SeO32−, and several antibiotics including streptomycin, cefotaxime, kanamycin, and chloramphenicol (Rodriguez-Rojas et al., 2015). On the other hand, global distillation and grasshopper effect are of major worldwide concern since they apparently provide an explanation for the rapid occurrence of heavy metal/metalloids contamination in pristine polar environments (Ebinghaus et al., 2002; Macdonald et al., 2005). In this context, the genome sequence of P. putida ATH-43 represents an important information source of genetic resistance determinants to multiple stressors currently affecting the Antarctic ecosystem. In this report we present the first draft genome sequence of a P. putida strain isolated from the Antarctic continent. The shotgun sequencing strategy, assembly, and subsequent annotation showed that the ATH-43 strain possesses a wide spectrum of genetic determinants involved in heavy metal and antibiotic resistance, apparently to cope with extreme oxidative stress conditions. P. putida ATH-43 genome now forms part of the 65 genomes of this species registered at the NCBI database (September, 2016) and it is highly related with the endophytic strain P. putida W619, which is also resistant to several heavy metals. Further characterization of multi-metal resistant psychrotrophic bacteria such as P. putida ATH-43 will be promising to develop novel strategies for heavy metal bioremediation in low temperature environments. All genome data has been submitted to NCBI.
Solubility and Accumulation of Metals in Chinese Brake Fern, Vetiver and Rostrate Sesbania Using Chelating Agents

Greenhouse experiments were conducted to study the effects of chelating agents on the growth and metal accumulation of Chinese brake fern (Pteris vittata L.), vetiver (Vetiveria zizanioides L.), and rostrate sesbania (Sesbania rostrata L.) in soil contaminated with arsenic (As), Cu, Pb, and Zn. Among the five chelating agents used [ethylenediaminetriacetic acid (EDTA), hydroxyethylenediaminetriacetic acid (HEDTA), nitrilotriacetic acid (NTA), oxalic acid (OA), and phytic acid (PA)], OA was the best to mobilize As, EDTA to mobilize Cu and Pb, and HEDTA to mobilize Zn from soil, respectively. The biomass of vetiver was the highest, followed by rostrate sesbania. All chelating agents inhibited the growth of Chinese brake fern and rostrate sesbania, but HEDTA significantly increased the aboveground biomass of vetiver. Dry weights of both Chinese brake fern and rostrate sesbania decreased with increasing EDTA concentrations amended in the soil, especially in treatments with high EDTA concentrations. EDTA and HEDTA enhanced Cu, Zn, and Pb, but lowered As accumulation in all three plant species, except for As in vetiver, while OA significantly enhanced As accumulation in the aboveground part of vetiver. Concentrations of Cu, Zn, and Pb in the aboveground parts of plants increased significantly with the increase of EDTA concentrations and treatment time. In addition to As, Chinese brake fern also accumulated the highest Cu, Pb, and Zn in its aboveground parts among the three plant species grown in metal-contaminated soil with EDTA/HEDTA treatments. This species, therefore, can be used to simultaneously clean up As, Cu, Pb, and Zn from contaminated soils with the aid of EDTA or HEDTA.
Damaged DNA Binding Protein 2 in Reactive Oxygen Species (ROS) Regulation and Premature Senescence

Premature senescence induced by DNA damage or oncogene is a critical mechanism of tumor suppression. Reactive oxygen species (ROS) have been implicated in the induction of premature senescence response. Several pathological disorders such as cancer, aging and age related neurological abnormalities have been linked to ROS deregulation. Here, we discuss how Damaged DNA binding Protein-2 (DDB2), a nucleotide excision repair protein, plays an important role in ROS regulation by epigenetically repressing the antioxidant genes MnSOD and Catalase. We further revisit a model in which DDB2 plays an instrumental role in DNA damage induced ROS accumulation, ROS induced premature senescence and inhibition of skin tumorigenesis.
Latino Gay Men and Depression

Any discussion of Latino gay men must begin with several caveats. Understanding Latino gay men is a complex process because they are not a homogeneous group of men. First and foremost they are a reflection of the diverse and heterogeneous Latino community. Another important point that must be made is that in the Latino community a narrower conceptualization of homosexuality exists that limits the use of the term “gay” to a certain segment of the population. It is important to note that there is a difference between sexual identity and sexual behaviors. The discussion here will be limited to Latino men who self-identify as gay, queer, and/or homosexual. It will not include Latino men who have sex with men but who identify as bisexual or as heterosexual. In the United States, Latino gay men are considered to be a group of men who originate from Mexico, the Caribbean, or Central or South America. Those born in the United States are in many instances children of immigrants or descendents of the Spanish colonialists. They find themselves at different points in the process of acculturation and
Relationship between interaction with the mental commit robot and change of stress reaction of the elderly

We introduced mental commit robot to a health services facility for the aged. The aim was to clarify relationship between interaction with the robot and change of stress reaction by the level of 17-KS-S and 17-OHCS value in urine of elderly. A seal type mental commit robot was provided to the elderly four days a week for three weeks. Besides, we used the questionnaire concerning familiarity with the robot that was introduced as an index of the psychological influence that mental commit robot give the subjects. As the results, an excellent adjustment ability to the stress was shown. Moreover, it was shown that the introduction of mental commit robot had produced a good influence for the reduction of nursing staff's stress.
Technical Perspective: Optimized Wandering for Online Aggregation

There is a rich history in the DBMS research literature involving sampling to estimate the results of queries faster than they can be computed exactly. A particularly interesting example of this is “Online Aggregation” proposed by Hellerstein et al. in 1997 [2]. There the idea is to combine sampling with a creative and intuitive user interface. Briefly, when a query starts to run, Online Aggregation will quickly present an estimate of the result of the query (based on data sampled up to that point) and will also present a confidence interval around the estimate. As query execution continues, the estimate is refined, and the confidence interval shrinks. Hidden in this attractive idea, however, are some di cult challenges. As an example, for queries that involve joins, the sampling process is in general slow, especially if most of the tuples from one relation participating in the join “match” with only a few tuples in the other relation. For 20 years the state of the art approach to this problem has been the “Ripple Join” [1]. The following paper by Li, Wu, Yi, and Zhao presents a highly e↵ective alternative. The main idea behind the wander join is to use the presence of indexes to speed the sampling, e↵ectively making a random walk through the data join graph. The details of doing this e ciently (both computationally and statistically) are not obvious. The authors of this paper use a clever combination of sampling strategies from the statistical literature and an on-line optimization process to order the paths chosen for the random walk, in the process achieving much better computational and statistical properties than the previously state of the art algorithm. The authors convincingly prove this through experimentation with an open-source implementation in the Postgres database management system.
Assessment of Coronary Artery Disease by Cardiac Computed Tomography: A Scientific Statement From the American Heart Association Committee on Cardiovascular Imaging and Intervention, Council on Cardiovascular Radiology and Intervention, and Committee on Cardiac Imaging, Council on Clinical Cardiolog

This scientific statement reviews the scientific data for cardiac computed tomography (CT) related to imaging of coronary artery disease (CAD) and atherosclerosis. Cardiac CT is a CT imaging technique that accounts for cardiac motion, typically through the use of ECG gating. The utility and limitations of generations of cardiac CT systems are reviewed in this statement with emphasis on CT measurement of CAD and coronary artery calcified plaque (CACP) and noncalcified plaque. Successive generations of CT technology have been applied to cardiac imaging beginning in the early 1980s with conventional CT, electron beam CT (EBCT) in 1987, and multidetector CT (MDCT) in 1999. Compared with other imaging modalities, cardiac CT has undergone an accelerated …
Spatial Modelling of Soil-Transmitted Helminth Infections in Kenya: A Disease Control Planning Tool

Background Implementation of control of parasitic diseases requires accurate, contemporary maps that provide intervention recommendations at policy-relevant spatial scales. To guide control of soil transmitted helminths (STHs), maps are required of the combined prevalence of infection, indicating where this prevalence exceeds an intervention threshold of 20%. Here we present a new approach for mapping the observed prevalence of STHs, using the example of Kenya in 2009. Methods and Findings Observed prevalence data for hookworm, Ascaris lumbricoides and Trichuris trichiura were assembled for 106,370 individuals from 945 cross-sectional surveys undertaken between 1974 and 2009. Ecological and climatic covariates were extracted from high-resolution satellite data and matched to survey locations. Bayesian space-time geostatistical models were developed for each species, and were used to interpolate the probability that infection prevalence exceeded the 20% threshold across the country for both 1989 and 2009. Maps for each species were integrated to estimate combined STH prevalence using the law of total probability and incorporating a correction factor to adjust for associations between species. Population census data were combined with risk models and projected to estimate the population at risk and requiring treatment in 2009. In most areas for 2009, there was high certainty that endemicity was below the 20% threshold, with areas of endemicity ≥20% located around the shores of Lake Victoria and on the coast. Comparison of the predicted distributions for 1989 and 2009 show how observed STH prevalence has gradually decreased over time. The model estimated that a total of 2.8 million school-age children live in districts which warrant mass treatment. Conclusions Bayesian space-time geostatistical models can be used to reliably estimate the combined observed prevalence of STH and suggest that a quarter of Kenya's school-aged children live in areas of high prevalence and warrant mass treatment. As control is successful in reducing infection levels, updated models can be used to refine decision making in helminth control.
Drosophila melanogaster Myosin-18 Represents a Highly Divergent Motor with Actin Tethering Properties

The gene encoding Drosophila myosin-18 is complex and can potentially yield six alternatively spliced mRNAs. One of the major features of this myosin is an N-terminal PDZ domain that is included in some of the predicted alternatively spliced products. To explore the biochemical properties of this protein, we engineered two minimal motor domain (MMD)-like constructs, one that contains the N-terminal PDZ (myosin-18 M-PDZ) domain and one that does not (myosin-18 M-ΔPDZ). These two constructs were expressed in the baculovirus/Sf9 system. The results suggest that Drosophila myosin-18 is highly divergent from most other myosins in the superfamily. Neither of the MMD constructs had an actin-activated MgATPase activity, nor did they even bind ATP. Both myosin-18 M-PDZ and M-ΔPDZ proteins bound to actin with Kd values of 2.61 and 1.04 μm, respectively, but only about 50–75% of the protein bound to actin even at high actin concentrations. Unbound proteins from these actin binding assays reiterated the 60% saturation maximum, suggesting an equilibrium between actin-binding and non-actin-binding conformations of Drosophila myosin-18 in vitro. Neither the binding affinity nor the substoichiometric binding was significantly affected by ATP. Optical trapping of single molecules in three-bead assays showed short lived interactions of the myosin-18 motors with actin filaments. Combined, these data suggest that this highly divergent motor may function as an actin tethering protein.
Lexicons in the MikroKosmos Project

Our approach to the lexicon has been driven by both theoretical and practical concerns. From a theoretical viewpoint, we are interested in capturing the core meanings of texts. We believe that lexical semantics is a crucial knowledge component of text meaning derivation, as it describes lexical meanings in their composition and combination properties. A major tenet of our methodology is a separation of what is language-dependent and what is universal in semantic speci cations. To help in determining this, our research methodology centrally includes a cross-linguistic perspective. From a practical standpoint, our lexicons are designed to support machine translation (MT) systems, in which the issue of multilinguality is clearly central. Theoretical and practical concerns are combined into the Mikrokosmos ( K ) approach, where, within the paradigm of knowledge-based machine translation (KBMT), we build lexicons for di erent natural languages, relying on a multilingual framework. All the central lexicons in KBMT are essentially bilingual, in that they provide mappings from a natural language into an arti cial knowledge-representation language, and vice versa. The lexicon structure used in the K approach is universal, in that it does not change from language to language and the arti cial language used in each lexicon (whether for Spanish, Japanese, Russian, English, etc.) is the same language of representation, called Text Meaning Representation (TMR) in K . Thus each language's lexicon provides a mapping for each word sense into a meaning representation in the TMR language, in addition to providing extensive information about the behavior of the word in utterances in that natural language. In the following sections, we brie y discuss the di erent issues we would like to raise at the workshop. In section 2, we illustrate how are our lexicons organized, the format we adopted, and what types of information we encode in them. In Section 3, we justify the choices made in Section 2 in terms of content and representations and also directly address the issue of multilinguality of lexical meaning representations. Finally, we describe some tools needed to acquire and check the entries we are building.
Pneumothorax after Shoulder Arthroscopy: A Rare but Life-threatening Complication

Introduction: Arthroscopy has become a major diagnostic tool and treatment option for shoulder pathology. However rare, respiratory complications such as a pneumothorax have been reported in patients undergoing shoulder arthroscopy. Surgery - as well as anesthesiology-related factors and respiratory comorbidity have been hypothesized to intervene in the onset of respiratory complications. Case Report: We report the case of a 42-year-old male patient who underwent an arthroscopy of the left shoulder. The anesthesia, the surgical procedure as well as the post-operative course went uncomplicated. The patients were discharged 6 h after the end of the surgical procedure. 4 h after discharge, however, the patient developed severe respiratory distress and signs of hemodynamic shock due to an ipsilateral (tension) post-operative pneumothorax. The available literature is reviewed focusing on the possible pathogenic mechanisms implying the development of this complication. Conclusion: The presence of a pneumothorax after shoulder arthroscopy is a rare but dangerous complication. It can primarily be attributed to rupture of parietal pleura, rupture of visceral pleura, and alveolar rupture or trauma during anesthesia. In our patient, we speculate that a rupture of parietal pleura was the underlying cause. This can be related to the surgical methodology (portal placement and continuous pump infusion with intermittent suction) and subacromial distention used during the procedure. Awareness, prompt recognition, and treatment are necessary.
The labial-coronal effect and CVCV stability during reiterant speech production: an acoustic analysis

This study investigates the stability of LC (Labial-Coronal) and CL (Coronal-Labial) CVCV sequences during a repetition task at an increasing rate. Despite variability between subjects and differences linked to the various consonant manners of articulation used in the study, the results show that the LC pattern is more stable than the CL pattern. Indeed, under the rate pressure, CL sequences often evolved to LC ones (e.g. /sapa/ switched to /pasa/) whereas the reverse pattern almost never happened. Coupled with previous studies about world languages, speech development and verbal transformation experiments, this is interpreted as a possible influence of the substance on phonological forms.