Miracle-dz/UniFAR-FTUs huggingface dataset:
Drug-eluting stents compared to bare-metal stents improve short-term survival in patients with acute myocardial infarction undergoing primary percutaneous coronary intervention: a nationwide prospective analysis of the AMIS Plus registry.

BACKGROUND Recently, it has been suggested that the type of stent used in primary percutaneous coronary interventions (pPCI) might impact upon the outcomes of patients with acute myocardial infarction (AMI). Indeed, drug-eluting stents (DES) reduce neointimal hyperplasia compared to bare-metal stents (BMS). Moreover, the later generation DES, due to its biocompatible polymer coatings and stent design, allows for greater deliverability, improved endothelial healing and therefore less restenosis and thrombus generation. However, data on the safety and performance of DES in large cohorts of AMI is still limited. AIM To compare the early outcome of DES vs. BMS in AMI patients. METHODS This was a prospective, multicentre analysis containing patients from 64 hospitals in Switzerland with AMI undergoing pPCI between 2005 and 2013. The primary endpoint was in-hospital all-cause death, whereas the secondary endpoint included a composite measure of major adverse cardiac and cerebrovascular events (MACCE) of death, reinfarction, and cerebrovascular event. RESULTS Of 20,464 patients with a primary diagnosis of AMI and enrolled to the AMIS Plus registry, 15,026 were referred for pPCI and 13,442 received stent implantation. 10,094 patients were implanted with DES and 2,260 with BMS. The overall in-hospital mortality was significantly lower in patients with DES compared to those with BMS implantation (2.6% vs. 7.1%,p < 0.001). The overall in-hospital MACCE after DES was similarly lower compared to BMS (3.5% vs. 7.6%, p < 0.001). After adjusting for all confounding covariables, DES remained an independent predictor for lower in-hospital mortality (OR 0.51,95% CI 0.40-0.67, p < 0.001). Since groups differed as regards to baseline characteristics and pharmacological treatment, we performed a propensity score matching (PSM) to limit potential biases. Even after the PSM, DES implantation remained independently associated with a reduced risk of in-hospital mortality (adjusted OR 0.54, 95% CI 0.39-0.76, p < 0.001). CONCLUSIONS In unselected patients from a nationwide, real-world cohort, we found DES, compared to BMS, was associated with lower in-hospital mortality and MACCE. The identification of optimal treatment strategies of patients with AMI needs further randomised evaluation; however, our findings suggest a potential benefit with DES.
Lexicography in an Interlingual Ontology: An Introduction to EuroWordNet

EuroWordNet is a multilingual lexical database constructed in the wake of WordNet. The ontological structure of the language-dependent layers, analogous to individual WordNets, through the semantic space of the interlingual index and abstract framework of the top level ontologies are examined. The semantic nature of the interlingual lexicon is examined as it applies to Gruber’s principles for the design of ontologies. Benefits of EuroWordNet’s design are highlighted. ordNet was originally proposed by Miller (1990) in an experiment to test an implementation of a model of lexical organization. Up to this point, ontological databases had been particularly small. WordNet was intended as a test of ontology design on a scale far larger than any existing lexical database, progressively incorporating the English lexicon into a large semantic database. W
High-frequency volatility of volatility estimation free from spot volatility estimates

We define a new consistent estimator of the integrated volatility of volatility based only on a pre-estimation of the Fourier coefficients of the volatility process. We investigate the finite sample properties of the estimator in the presence of noise contaminations by computing the bias of the estimator due to noise and showing that it vanishes as the number of observations increases, under suitable assumptions. In both simulated and empirical studies, the performance of the Fourier estimator with high-frequency data is investigated and it is shown that the proposed estimator of volatility of volatility is easily implementable, computationally stable and even robust to market microstructure noise.
Does Ill Health Affect Savings Intentions? Evidence from SHARE

This paper uses data from SHARE 2004 to analyze one possible causal pathway of the health-wealth gradient, namely differences in the marginal propensity to save and spend across different health states. Conditional on age and current wealth, I find weak relationships between health and the intended use of a hypothetical windfall gift as well bequest expectations. The overall effect of health on wealth through this link is positive but very small.
The Integration of Financial Services and Economic Welfare after `1992'

This paper uses a computable general-equilibrium model of intertemporal demand to investigate the impact of market integration after 1992 on financial services and economic welfare in the European Community (EC). In contrast to previous work, it assesses the impact of `1992' on the demand for and the allocation of resources in the economy and provides estimates of the effects on borrowers and lenders, sectoral employment and output, international trade in financial services, the balance of payments and economic welfare. The greater scope of the intermediation model in this paper, in addition to providing a greater range of results, suggests that the effects of market integration will be substantially larger than estimated in the Cecchini report, and that the gains (and losses) will differ substantially both within and across economies.
Rivalry Through Alliances: Competitive Strategy in the Global Telecommunications Market

This article is the first and the qualitative section of a two-part strategy research project which examines the state of the global telecommunications market and assesses the business factors and environmental variables such as country/regional economic profiles, political systems and regional alliances, that influence strategic directions of firms in the converging global telecommunications market. The article specifically investigates the forces contributing to the globalization of telecommunications services, major telecommunications strategies and strategic alliances in the global market, and factors that may have contributed to the outcome of these alliances.
Identification of new genes regulated by the marRAB operon in Escherichia coli

Random TnphoA and TnlacZ translational fusions were introduced into an Escherichia coli strain with a deletion of the multiple antibiotic resistance (mar) locus, complemented in trans by a temperature-sensitive plasmid bearing the mar locus with a constitutively expressed mar operon. Five gene fusions (two with lacZ and three with phoA) regulated by the mar operon were identified by increased or decreased marker enzyme activity following loss of the complementary plasmid at the restrictive temperature. Expression of LacZ from both lacZ fusions increased in the presence of the mar operon; expression from the three phoA fusions was represented by the mar operon. The lacZ fusions were mapped at 31.5 and 14 min on the Escherichia coli chromosome. One of the phoA fusions was located at 51.6 min while the two others mapped at 77 min. Cloning and sequencing of a portion of the fused genes showed all of them to be different. The phoA fusions at 77 min were located in a recently identified gene, slp, a lipoprotein of unknown function (D.M. Alexander and A. C. St. John, Mol. Microb. 11:1059-1071, 1994). The others showed no homology with any known genes of E. coli. The insertions caused small but reproducible changes in the antibiotic susceptibility profile. This approach has enabled the identification of new genes in E. coli which are regulated by the marRAB operon and involved in the Mar phenotype.
Control of Fork-Join Networks in heavy traffic

A Fork-Join Network (FJN) is a natural model for a queueing system in which customers, or rather tasks associated with customers, are processed both sequentially and in parallel. In this paper we analyze a network that, in addition, accommodates feedback of tasks. An example of a FJN is an assembly operation, where parts are first produced and then assembled to ultimately create a final product. Another example is an emergency department, where a patient “forks” into, say, a blood test and an X-ray, which must then “join” the patient as a prerequisite for a doctor examination. There is a fundamental difference between the dynamics of these two examples: In an assembly network, parts are exchangeable while, in an emergency department, tasks are associated uniquely with patients. They are thus nonexchangeable in the sense that one cannot combine/join tasks associated with different customers. In single-server feed-forward FJNs, FCFS processing maintains a fully synchronized flow of tasks. Probabilistic feedback, however, introduces flow disruptions that give rise to task delays and ultimately a decrease in throughput rate. Nevertheless, we show that a simple flow control of tasks can render this decrease of performance asymptotically negligible (though it is not absolutely negligible). More specifically, we analyze a concrete FJN, with nonexchangeable tasks and Markovian feedback, in the conventional heavy-traffic (diffusion) regime. We prove asymptotic equivalence between this network and its corresponding assembly network (exchangeable tasks), thus establishing asymptotic throughput-optimality of our control. The analysis also reveals further interesting properties, such as state-space collapse of synchronization queues.
A study of women's preferences regarding the formulation of over-the-counter vaginal spermicides

This study explored the characteristics of existing vaginal products--a gel suppository and film--that influence users preferences for various formulations. In addition the researchers also sought further knowledge on the risk of irritation to the vagina and cervix potentially associated with low to moderate use of spermicidal products containing nonoxynol-9. The study included 145 sexually active women who were enrolled in 5 sites [Cote dIvoire Zimbabwe US and Thailand (2 sites)]. These women were asked to use 3 different vaginal spermicide preparations containing nonoxynol-9 (a gel a film and a suppository) for 4 weeks; then structured interviews and clinical examinations were conducted at biweekly clinic visits. Prior to and following product use women participated in focus group discussions to explore their knowledge beliefs and practices surrounding vaginal product use. Results revealed that women enrolled in the New York City site were almost evenly divided in their preferences of the 3 formulations. In the Thai and Zimbabwe sites the film was the most preferred formulation because it was easy to use not too messy and did not produce a lot of discharge. In Cote dIvoire gel was the preferred formulation followed closely by film. In general the suppository was reported to be most messy with the tendency to melt prior to insertion in hotter climates. No significant irritations or lesions resulted from product use in any of the sites. In conclusion the formulation preferences of women should be considered in the development and introduction of vaginal microbicides.
Number of People in Each Zone Was Recorded Consecutively from Zone a to Zone F at the Beginning of Each 2 Minute Interval over the Observation Period, Using the Instantaneous Scan Sampling Technique (altmann 1974)

All times used in this study are New Zealand daylight saving time which is New Zealand standard time plus 1 hour, or GMT plus 13 hours. To assist in the analysis of the data the 2 minute sampling intervals were combined into 6 minute units, which were then numbered in relation to the conclusion of sampling (i.e., time unit 1 ran from 6 minutes prior to sampling finish until sampling finish, time unit 2 ran from 12 minutes prior to sampling finish until 6 minutes prior to sampling finish etc.). Penguin landing times were compared using two different analyses. The time until 25%, 50% and 75% of penguins had landed at each beach on each day was calculated. These three measures were then compared separately using univariate two-way analysis of variance, with the days and beaches as the sources of variation. Empirical cumulative distribution functions were also constructed for each beach on each day by calculating the percentage of the total penguins landing to have landed by the end of each successive six minute observation period. The empirical cumulative distributions for each beach were then compared on a pairwise basis for each day using the two-sample Kolmogorov-Smirnov test. All observations were used for this analysis as commencement time was irrelevant because of the pairwise nature of the test. If penguin landings at Sandfly Bay are unaffected by the presence of people, then the proportion of penguin landings occurring during periods when people were present should be equal to the proportion of time when people were present. Alternately, if the presence of people was affecting penguin landings we hypothesised that penguins would land proportionately less frequently when people were present. To evaluate this hypothesis the proportion of observation time (using the number of six minute observation periods as units) during which people were present in each zone was calculated (Number time units people present in zone = Total number of time units). The proportion of penguin landings occurring while people were present in each zone was also calculated (Number of penguin landings with people present = Total number of penguin landings). These two proportions were compared for each zone using a one-tailed z test, based on the normal approximation to the binomial.
Low birth weight and cardiovascular risk factors in Auckland adolescents: a retrospective cohort study.

AIMS To determine whether birth weight is inversely associated with cardiovascular risk factors in a multiethnic sample of New Zealand adolescents. METHODS A retrospective cohort with birth weight collected from hospital records of 855 (68%) out of 1260 Auckland-born students who had blood pressure, fasting blood lipids, and glucose measured while in Year 11-13 at high school. RESULTS After controlling for sex, age, and ethnicity, none of the following cardiovascular risk factors were associated with birth weight (p>0.05): systolic and diastolic blood pressure, total cholesterol, HDL cholesterol, triglycerides, and glucose. Serum cholesterol came closest to statistical significance: regression coefficient being--0.10 mmol/L (SE=0.06, p value=0.11). In contrast (after controlling for age, sex, and ethnicity), current Body Mass Index (BMI) was significantly (p<0.05) related to all above cardiovascular risk factors. The proportion of students with elevated serum cholesterol levels (top 20%) attributable to elevated BMI (>30 kg/m2) was 18%, and that attributable to low birth weight (<2.5 kg) was 2%. CONCLUSIONS These results do not support for the 'fetal origins' hypothesis. The very low proportion of adolescents with elevated coronary risk factors attributed to low birth weight suggests that the focus of cardiovascular disease prevention should remain in adolescence and adulthood, rather than in pregnancy.
The Research of Coverage Control Algorithm for Wireless Sensor Network

Wireless sensor networks is a multi-hop self-organizing networks system that consist with vast majority of low-cost node arrayed in the monitor area and formed by wireless technology. This paper is oriented to the demand of preferential energy efficiency and brings forward related control algorithm solution to the heated questions about decreasing network energy-consumption and realizing energy-balance. Based on general probability perceptive model, two coverage control algorithms are put forward respectively. The main idea of algorithm is to make use of a few of higher energy left nodes to buildup network coverage sets and connectivity coverage sets. Reset the cycle of next coverage sets until last sets expire. Use different nodes to form the coverage sets as much as possible to in every new cycle to decrease and balance the energy-consumption.
Review of Low Power Testing Techniques

the circuit consumes more power during test mode compared to functional mode. So test power has been major big concern in large System-on-Chip designs from last decade. In this review paper, the state-of-the-art in low power testing is presented. The paper contains the detailed survey on various power reduction techniques proposed for both the aspects of testing i.e. external testing as well as Built-In-Self-Test. The advances in DFT techniques emphasizing low power are also included in this survey
Prevention of Endotoxaemia in Obstructive Jaundice — a Comparative Study of Bile Salts

Systemic endotoxaemia is associated with postoperative renal dysfunction in obstructive jaundice, and can be prevented by the pre-operative administration of certain bile salts. In order to find the most effective bile salt for use in this condition, a comparison of the anti-endotoxic activities of different bile salts was performed. Bile salts were incubated in vitro with endotoxin and the resultant endotoxin level was measured with a quantitative limulus assay. The in vivo effects of different oral bile salts on the intestinal absorption of radiolabelled endotoxin from rats with obstructive jaundice were compared. The in vitro and in vivo anti-endotoxic activities of bile salts related to their known detergent activities. Deoxycholic acid and its conjugates were the most effective and should be the bile salts of choice for further clinical evaluation in obstructive jaundice in man.
The Role of XML in Open Hypermedia Systems

The World Wide Web Consortium [W3C] has recently issued XML 1.0 as a Recommendation [XML]. XML, the Extensible Markup Language, is a data format for structured document interchange on the Web. In this paper, we put forward the position that XML, together with (future) standards based on XML, will play an important role in the development of open hypermedia systems. Many of objectives of the XML community are similar to the objectives of the open hypermedia systems (OHS) community. This paper discusses these similarities, but also stresses the differences between the architecture and protocol-oriented approach which is typical for the OHS research community versus the document oriented approach of the XML community.
A Parameterized Approximation Algorithm for The Shallow-Light Steiner Tree Problem

For a given graph $G=(V,\, E)$ with a terminal set $S$ and a selected root $r\in S$, a positive integer cost and a delay on every edge and a delay constraint $D\in Z^{+}$, the shallow-light Steiner tree (\emph{SLST}) problem is to compute a minimum cost tree spanning the terminals of $S$, in which the delay between root and every vertex is restrained by $D$. This problem is NP-hard and very hard to approximate. According to known inapproximability results, this problem admits no approximation with ratio better than factor $(1,\, O(\log^{2}n))$ unless $NP\subseteq DTIME(n^{\log\log n})$ \cite{khandekar2013some}, while it admits no approximation ratio better than $(1,\, O(\log|V|))$ for D=4 unless $NP\subseteq DTIME(n^{\log\log n})$ \cite{bar2001generalized}. Hence, the paper focus on parameterized algorithm for \emph{SLST}. We firstly present an exact algorithm for \emph{SLST} with time complexity $O(3^{|S|}|V|D+2^{|S|}|V|^{2}D^{2}+|V|^{3}D^{3})$, where $|S|$ and $|V|$ are the number of terminals and vertices respectively. This is a pseudo polynomial time parameterized algorithm with respect to the parameterization: "number of terminals". Later, we improve this algorithm such that it runs in polynomial time $O(\frac{|V|^{2}}{\epsilon}3^{|S|}+\frac{|V|^{4}}{\epsilon}2^{|S|}+\frac{|V|^{6}}{\epsilon})$, and computes a Steiner tree with delay bounded by $(1+\epsilon)D$ and cost bounded by the cost of an optimum solution, where $\epsilon>0$ is any small real number. To the best of our knowledge, this is the first parameterized approximation algorithm for the \emph{SLST} problem.
Properties of the interface of the symbiotic branching model

The symbiotic branching model describes the evolution of two interacting populations and if started with complementary Heaviside functions, the interface where both populations are present remains compact. In this paper, we show tightness of the diusively rescaled solutions and thus provide a rst step towards a scaling limit for the interface. The crucial estimate involves a mixed fourth moment bound which we analyse using a particle system duality. As a corollary, we obtain an estimate on the moments of the width of an approximate interface. 2010 Mathematics Subject Classication : Primary 60K35, Secondary 60J80.
Recommends System using Re-extraction methods on the Groups with a similarity pattern such as Clustered User's preference tendency

As the amount of information provided to the customer becomes larger, unnecessary information can lead to difficulty in finding the information customer wanted. This also may lead to a customer being dissatisfied with the service. However, the existing systems that apply a similar concept fail to address the individual user's demands. In addition, in considering similarities between users, each item's relative importance (weighted value) to each customer are not being taken into account. This leads to problems of scarcity if the common preference items are small and also the problems of expansion, where system slowdown occurs as number of users increase. These inefficiency problems are dealt with, in this paper, an adaptive e-commerce agent system is proposed to cater for individual user's taste for products. This system includes a monitoring agent that monitors user's intentions, a similarity referencing agent that learns user's activities to reference a group with a similar pattern, and an interest extraction agent that creates and updates individual user's activity database whenever change in activity is detected
Imaging and Quantification of 3 D Brain Vasculature in a Mouse Model for Alzheimer ’ s Disease

1 Dept. of Neurobiology, University of Zurich, Zurich, Switzerland; 2 Institute for Biomedical Engineering, ETH and University, Zurich, Switzerland 3 Swiss Light Source, Paul Scherrer Institute, Villigen, Switzerland; 4 Novartis Institutes for BioMedical Research Inc. Cambridge, USA Vascular factors associated with Alzheimer’s disease (AD) have recently gained increased attention. To investigate changes in brain vasculature, particularly of the microvascular architecture, we developed a hierarchical imaging framework to obtain large-volume, high-resolution 3D images from corrosion casted brains of transgenic mice modeling Alzheimer’s disease.
Instruction Placement for an EDGE Multicore Processor Using Reinforcement Learning

Communication overheads are one of the fundamental challenges in a multiprocessor system. As the number of processors on a chip increases, communication overheads and the distribution of computation and data become increasingly significant. The granularity of communication between processors on a single chip in future systems will determine how significant these overheads will be. Fine-grained communication may expose more parallelism, but at the cost of higher overheads. Coarser-grained communication limits the impact of these overheads, but it may be difficult to expose the same degree of parallelism without the benefits of fine-grained communication. In this work, we attempt to show that the compiler can be effectively used to minimize these fine-grained communication delays in an EDGE processor. We use a reinforcment learning technique called Neuro-Evolution of Augmenting Topologies (NEAT) to aid the compiler in achieving this goal.