Miracle-dz/UniFAR-FTUs huggingface dataset:
A robust quadratically constrained adaptive blind multiuser receiver for cellular DS/CDMA systems

A new low-computational complexity robust adaptive blind multiuser receiver based on a constrained optimization approach with multiple constraints and a quadratic inequality (QI) constraint on the weight vector norm is developed. A diagonal loading technique is required to apply the quadratic constraint where the diagonal loading value is adjusted to satisfy the constrained value. Implementing the quadratic constraint into adaptive update algorithms such as least-mean-square (LMS) or recursive-least-mean (RLS) seems to be a difficult task. The minimum output energy (MOE) detector is implemented using a new adaptive algorithm based on the partition linear interference canceller (PLIC) structure with multiple constraints and a QI constraint on the weight vector norm. A new optimal variable loading (VL) technique, which is capable of providing robust control against signal mismatch with low computational complexity, is adopted. Simulations in a rich multipath environment with near-far effect are presented to demonstrate the robustness and fidelity of the proposed detector.
The eastward subtropical countercurrent in the western North Pacific Ocean

Through an analytical study of the existing data , including those from CSK (196566), in the subtropical region of the western North Pacific Ocean, the existence of a new eastward "Subtropical Countercurrent" is strongly indicated nearly along the Tropic of Cancer. The isotherms for 21•‹•`24•Ž at 100 m show close agreement with the current path. The Countercurrent, showing a velocity of 0.2•`1.3 knots (0.5 knot on the average), was revealed on the geostrophic-current field throughout the year. The width and thickness of the Countercurrent are about 100 miles and 300 m, respectively. Its transport is 10•`20 % of that of the Kuroshio. We can trace the Countercurrent from 122•‹E at least to 160•‹E, and probably farther to the east. Surface-current maps (based on ship-log data collected in 1924-34 and published by Japan Hydrographic Office) for the four seasons also indicate the eastward Subtropical Countercurrent at 20•‹•`25•‹N. Two different thermal fronts are found in the subtropical North Pacific. One of the fronts is in the surface mixed layer and migrates north and south seasonally with varying intensity. The other strong front, which is associated with the Subtropical Countercurrent, is found at 100•`200 m near the Tropic of Cancer and marks the line of demarcation between the Subtropical Mode Water on the north and the Tropical Water on the south. A similar Subtropical Countercurrent is expected to exist in the North Atlantic.
Effelsberg H I observations of compact high-velocity clouds

We have mapped 11 compact high-velocity clouds (CHVCs) in the 21-cm line emission of neutral, atomic hydrogen, using the Effelsberg 100-m radio telescope. The aim of our observations was to study the overall distribution of the warm neutral medium of CHVCs with high sensitivity. The achieved baseline rms of σrms ≈ 50 mK at the original 2. 6k m s −1 velocity resolution allows us to search for evidence of ram-pressure interaction with the ambient medium. In addition, we have obtained spectra along an appropriate axis across each CHVC with longer integration times and denser angular sampling. These deep slices with σrms ≈ 25 . 35 mK allow us to determine the column density profile in greater detail as well as the velocity and line width gradient across each cloud. The most outstanding result of our observations is the complexity of the H  column density distribution and the line profiles of the investigated CHVCs. We have found only one cloud with a spherically-symmetric appearance. Among the remaining clouds we observe head-tail structures, bow-shock shapes, and objects with irregular shapes. These complex morphologies in combination with the obtained physical parameters suggest that ram-pressure interactions with an ambient medium may play a significant role in shaping some of the CHVCs from our sample. These results are consistent with a circumgalactic distribution of CHVCs with typical distances of the order of 100 kpc. The pressure of the ambient medium might also stabilise CHVCs in addition to their own gravitational potential.
Online velocity planner for Laser Guided Vehicles subject to safety constraints

Laser Guided Vehicles (LGV) are largely used in industrial contexts for the autonomous dispatching of huge loads. LGVs of automated warehouses are driven by supervisory systems which assign their tasks depending on the process demands. The vehicle workspace is partially structured and it is normally shared with several independent agents like other LGVs, or human operated forklifts, or humans which directly interact with the vehicle itself. For efficiency and for safety reasons, LGVs move along pre-defined paths so that, if an unexpected obstacle is detected, they must be promptly stopped so as to avoid impacts. As shown in the paper, the safety problem is normally handled by limiting the plant productivity. This is clearly an improper approach, which can be overcome by considering a novel velocity planning strategy. The one proposed in this paper guarantees high safety standards, thus preserving the physical integrity of human coworkers, by simultaneously improving the plant productivity.
Expanding the Concept of G Protein-Coupled Receptor (GPCR) Dimer Asymmetry towards GPCR-Interacting Proteins

G protein-coupled receptors (GPCRs), major targets of drug discovery, are organized in dimeric and/or oligomeric clusters. The minimal oligomeric unit, the dimer, is composed of two protomers, which can behave differently within the dimer. Several examples of GPCR asymmetry within dimers at the level of ligand binding, ligand-promoted conformational changes, conformational changes within transmembrane domains, G protein coupling, and most recently GPCR-interacting proteins (GIPs), have been reported in the literature. Asymmetric organization of GPCR dimers has important implications on GPCR function and drug design. Indeed, the extension of the “asymmetry concept” to GIPs adds a new level of specific therapeutic intervention.
On Large Scale Peer-To-Peer Video Streaming: Experiments and Empirical Studies

It is an attractive idea to spread real time media using peer-to-peer method, however nobody knows if this technology can really deliver real time media to large number of users in global scale. This paper presents an empirical study on CoolStreaming, a data-driven overlay network for live media streaming. The core operations in CoolStreaming are very simple: every node periodically exchanges data availability information with a set of partners, and retrieves unavailable data from one or more partners, or supplies available data to partners. We have extensively evaluated the performance of CoolStreaming over real Internet environment. Our experiments, involving more than 10,000 real users, demonstrate that CoolStreaming can achieve quite good streaming quality even under global scaled, formidable network conditions. Meanwhile, we present several interesting observations from these large-scale tests. Finally, we try to predict some directions to the future of p2p media streaming
Three-Dimensional Transcranial Ultrasound Imaging of Microbubble Clouds Using a Sparse Hemispherical Array

There is an increasing interest in bubble-mediated focused ultrasound (FUS) interventions in the brain. However, current technology lacks the ability to spatially monitor the interaction of the microbubbles with the applied acoustic field, something which is critical for safe clinical translation of these treatments. Passive acoustic mapping could offer a means for spatially monitoring microbubble emissions that relate to bubble activity and associated bioeffects. In this study, a hemispherical receiver array was integrated within an existing transcranial therapy array to create a device capable of both delivering therapy and monitoring the process via passive imaging of bubble clouds. A 128-element receiver array was constructed and characterized for varying bubble concentrations and source spacings. Initial in vivo feasibility testing was performed. The system was found to be capable of monitoring bubble emissions down to single bubble events through an ex vivo human skull. The lateral resolution of the system was found to be between 1.25 and 2 mm and the axial resolution between 2 and 3.5 mm, comparable to the resolution of MRI-based temperature monitoring during thermal FUS treatments in the brain. The results of initial in vivo experiments show that bubble activity can be mapped starting at pressure levels below the threshold for blood-brain barrier disruption. This study presents a feasible solution for imaging bubble activity during cavitation-mediated FUS treatments in the brain.
Underuse of Primary Care in China: The Scale, Causes, and Solutions

Strengthening the primary care system and promoting utilization of primary care are the major targets of China's ambitious health reforms to meet its people's escalating health care needs. However, the changing trend of primary care utilization 4 years before and after 2009, when the health reforms started, is against the government's stated goal. The percentage of outpatient visits in primary care significantly declined from 63% in 2005 to 59% in 2013 (P = .002). In Western China it went down from 66% in 2010 to 62% in 2013 (P = .017) and slightly dropped in Eastern and Central China. Causes are multiple and include major historic and institutional factors such as severe maldistribution of human resources and lack of primary care practitioners (PCPs), lack of a functional gate-keeping mechanism, the low educational attainment of PCPs, and the detrimental elements of health reforms. Immediate measures need to be taken to improve the situation. These include taking irrational hospital expansion under strict control through enhancing the government's accountability for health care industry regulation, strategies to recruit and retain a quality primary care workforce, empowering PCPs as gatekeepers in the system, timely evaluation of the impact of health reforms on primary care, and modifying damaging policies.
Testing and Breeding Forest Trees for Plantations in the Northern Territory

This report is about research to identify and improve forest trees for sawlog production in the Top End (1000-1800 mm rainfall zone) of the Northern Territory (NT). The report outlines the successful establishment of four trials to test species and provenance performance, and to establish breeding and seed production orchards. The species trials tested a wide range of eucalypt, acacia, hybrid and exotic species. Seed orchards were established for red mahogany Eucalyptus pellita and African mahogany Khaya senegalensis. Early results for growth and species performance are given for the species-provenance trials.
Pheophytin a Inhibits Inflammation via Suppression of LPS-Induced Nitric Oxide Synthase-2, Prostaglandin E2, and Interleukin-1β of Macrophages

Inflammation is a serious health issue worldwide that induces many diseases such as sepsis. There has been a vast search for potentially effective drugs to decrease mortality from sepsis. Pheophytin a is a chlorophyll-related compound derived from green tea. We found that pre-treatment with pheophytin a suppressed lipopolysaccharide (LPS)-induced nitric oxide (NO), prostaglandin E2 (PGE2), and interleukin-1β in RAW 264.7 macrophages. NO synthase-2 (NOS2) and cyclooxygenase-2 (COX-2) expression levels were repressed by pre-treatment with pheophytin a at both the transcriptional and translational levels. Pheophytin a inhibited NOS2 promoter activity, but not its mRNA stability, through extracellular signal-regulated kinase (ERK1/2). This suppression was reversed by ERK1/2 inhibitor (U0126). Pheophytin a reduced signal transducers and activators of transcription 1 (STAT-1) activation, without an obvious influence on activator protein-1 (AP-1) and nuclear factor κB (NF-κB). These results suggest that pheophytin a functions by down-regulating the transcriptional levels of inflammatory mediators and blocking the ERK and STAT-1 pathways.
Cerebral venous sinus thrombosis in early pregnancy: An unusual presentation of primary antiphospholipid syndrome

Cerebral venous sinus thrombosis, an unusual presentation of antiphospholipid syndrome, is a rare condition in pregnancy, particularly in the first trimester. The authors of this case report present the case of a 20‐year‐old woman with sudden onset of headaches and hemiparesis in the first trimester of pregnancy. She underwent a computed tomography scan and magnetic resonance imaging. The image findings and the autoimmune serum test were consistent with a cerebral venous sinus thrombosis complicated by primary antiphospholipid syndrome. The patient's hemiparesis improved with subcutaneous low molecular weight heparin and oral aspirin. In the third trimester of pregnancy, she developed seizures that were controlled by antiepileptic drugs. She delivered a healthy baby at 37 weeks' gestation without immediate or late postpartum complications.
Epstein-Barr virus nuclear antigens 3C and 3A maintain lymphoblastoid cell growth by repressing p16INK4A and p14ARF expression

Epstein-Barr virus (EBV) nuclear antigen 3C (EBNA3C) and EBNA3A are each essential for EBV conversion of primary human B lymphocytes into continuously proliferating lymphoblast cell lines (LCLs) and for maintaining LCL growth. We now find that EBNA3C and EBNA3A's essential roles are to repress p16INK4A and p14ARF. In the absence of EBNA3C or EBNA3A, p16INK4A and p14ARF expression increased and cell growth ceased. EBNA3C inactivation did not alter p16INK4A promoter CpG methylation, but reduced already low H3K27me3, relative to resting B cells, and increased H3K4me3 and H3-acetylation, linking EBNA3C inactivation to histone modifications associated with increased transcription. Importantly, knockdown of p16INK4A or p14ARF partially rescued LCLs from EBNA3C or EBNA3A inactivation-induced growth arrest and knockdown of both rescued LCL growth, confirming central roles for p16INK4A and p14ARF in LCL growth arrest following EBNA3C or EBNA3A inactivation. Moreover, blockade of p16INK4A and p14ARF effects on pRb and p53 by human papilloma virus type 16 E7 and E6 expression, sustained LCL growth after EBNA3C or EBNA3A inactivation. These data indicate that EBNA3C and EBNA3A joint repression of CDKN2A p16INK4A and p14ARF is essential for LCL growth.
Multi-view face detection and pose estimation employing edge-based feature vectors

A multi-view face detection and pose estimation system has been developed employing the edge-based feature representations. Using the posed face images at four angles: 0°, 30°, 60°, and 90° as templates, the performance of pose estimation of about 80% has been achieved for test images in the entire angle range of 0° - 90°. In order to further enhance the performance, the concept of focus-of-attention (FOA) has been introduced in the vector generation. Namely, edge-based feature vectors are generated from the restricted area mostly containing essential information of facial images. As a result, the detection rate has been enhanced to more than 90% for profile images, which is difficult to achieve when original edge-based vectors are used.
Atlas of the Multiphysical Models of Westen Siberia Reservoir

Summary ATLAS is the collection of multiphysical models of the typical reservoirs of Western Siberia. Both geomechanical, hydrodynamic, geoelectric processes in the vicinity of the borehole and electrical and electromagnetic well logs are jointly analyzed. The influence of each of the hydrophysical and geomechanical parameters on the process of mud filtrate invasion into the formation, evolution of the electrical resistivity distribution in the borehole environment, the electric and electromagnetic logs can be studied and visualised by using ATLAS. Further development of ATLAS is aimed to creating interpreting system of the well geophysical and geological-technological studies on the basis of multiphysical reservoir models.
Using a Hypertext Model for Traceability Link Conformance Analysis

A number of techniques for semi-automated traceability link recovery between source code and documentation have recently been proposed to support the reverse engineering and maintenance of legacy systems. This is only the first step in supporting the long term maintainability of such systems. A crucial issue, after recovering traceability links is analyzing their general conformance over time. That is, as a system is changed during evolution the validity and conformance of the links may change. Thus, conformance analysis must be performed to identify possible non-conformance of the links. The paper presents a holistic view of how to combine link recovery with conformance analysis that is facilitated by a formal hypertext model. This hypertext model not only supports complex linking structures (e.g., multi links) but also supports versioning of individual links. Such a model preserves and maintains over time the results of the reverse engineered traceability links.
Identification of Novel Type III Effectors Using Latent Dirichlet Allocation

Among the six secretion systems identified in Gram-negative bacteria, the type III secretion system (T3SS) plays important roles in the disease development of pathogens. T3SS has attracted a great deal of research interests. However, the secretion mechanism has not been fully understood yet. Especially, the identification of effectors (secreted proteins) is an important and challenging task. This paper adopts machine learning methods to identify type III secreted effectors (T3SEs). We extract features from amino acid sequences and conduct feature reduction based on latent semantic information by using latent Dirichlet allocation model. The experimental results on Pseudomonas syringae data set demonstrate the good performance of the new methods.
Episodic Memory Retrieval Functionally Relies on Very Rapid Reactivation of Sensory Information

Episodic memory retrieval is assumed to rely on the rapid reactivation of sensory information that was present during encoding, a process termed “ecphory. ” We investigated the functional relevance of this scarcely understood process in two experiments in human participants. We presented stimuli to the left or right of fixation at encoding, followed by an episodic memory test with centrally presented retrieval cues. This allowed us to track the reactivation of lateralized sensory memory traces during retrieval. Successful episodic retrieval led to a very early (∼100–200 ms) reactivation of lateralized alpha/beta (10–25 Hz) electroencephalographic (EEG) power decreases in the visual cortex contralateral to the visual field at encoding. Applying rhythmic transcranial magnetic stimulation to interfere with early retrieval processing in the visual cortex led to decreased episodic memory performance specifically for items encoded in the visual field contralateral to the site of stimulation. These results demonstrate, for the first time, that episodic memory functionally relies on very rapid reactivation of sensory information. SIGNIFICANCE STATEMENT Remembering personal experiences requires a “mental time travel” to revisit sensory information perceived in the past. This process is typically described as a controlled, relatively slow process. However, by using electroencephalography to measure neural activity with a high time resolution, we show that such episodic retrieval entails a very rapid reactivation of sensory brain areas. Using transcranial magnetic stimulation to alter brain function during retrieval revealed that this early sensory reactivation is causally relevant for conscious remembering. These results give first neural evidence for a functional, preconscious component of episodic remembering. This provides new insight into the nature of human memory and may help in the understanding of psychiatric conditions that involve the automatic intrusion of unwanted memories.
A preliminary analysis of the relationship of speech rate to speech-timing metrics as applied to large corpora of non-laboratory speech in English and Chinese broadcast news

A renewed interest, in recent years, has occurred in the area of speech rhythm (traditionally defined by categories of speech timing patterns based on perceptual or acoustic durations of stresses, syllables, or moras). Since accurate categorization seems to be a three dimensional problem (durations of vocalic intervals, intervocalic intervals
Abnormal Neural Responses to Social Exclusion in Schizophrenia

Social exclusion is an influential concept in politics, mental health and social psychology. Studies on healthy subjects have implicated the medial prefrontal cortex (mPFC), a region involved in emotional and social information processing, in neural responses to social exclusion. Impairments in social interactions are common in schizophrenia and are associated with reduced quality of life. Core symptoms such as delusions usually have a social content. However little is known about the neural underpinnings of social abnormalities. The aim of this study was to investigate the neural substrates of social exclusion in schizophrenia. Patients with schizophrenia and healthy controls underwent fMRI while participating in a popular social exclusion paradigm. This task involves passing a ‘ball’ between the participant and two cartoon representations of other subjects. The extent of social exclusion (ball not being passed to the participant) was parametrically varied throughout the task. Replicating previous findings, increasing social exclusion activated the mPFC in controls. In contrast, patients with schizophrenia failed to modulate mPFC responses with increasing exclusion. Furthermore, the blunted response to exclusion correlated with increased severity of positive symptoms. These data support the hypothesis that the neural response to social exclusion differs in schizophrenia, highlighting the mPFC as a potential substrate of impaired social interactions.
Hypoglycaemia, Abnormal Lipids, and Cardiovascular Disease among Chinese with Type 2 Diabetes

We recruited a group of 6713 consecutive Chinese patients with T2D but normal renal and liver function who were admitted to one of 81 top tertiary care hospitals in China. Mild hypoglycaemia was defined as having symptomatic hypoglycaemia in one month before hospitalization. Severe hypoglycaemia was defined as having hypoglycaemia that needed assistance from other people in three months before hospitalization. Prior cardiovascular disease (CVD) was defined as having coronary heart disease, stroke, or peripheral arterial disease. Of 6713 patients, 80 and 304 had severe and mild hypoglycaemia episodes, respectively, and 561 had CVD. Patients with severe and mild hypoglycaemia episodes were more likely to have prior CVD (32.5% versus 16.5% versus 7.7%, P < 0.0001). Both mild and severe hypoglycaemia were associated with increased risk of CVD (adjusted odds ratios (ORs): 2.64, 95% CI: 1.85–3.76 for mild hypoglycaemia; 6.59, 95% CI: 3.79–11.45 for sever hypoglycaemia) than those patients free of hypoglycaemia. Further adjustment for lipid profile did not change these two ORs. In the same way, the ORs of lipid profile for CVD were similar before and after adjustment for hypoglycaemia. We concluded that hypoglycaemia and lipid profile were independently associated with increased risk of CVD.
Parochial Politics: Ethnic Preferences and Politician Corruption

This paper examines how increased voter ethnicization, defined as a greater preference for the party representing one's ethnic group, affects politician quality. If politics is characterized by incomplete policy commitment, then ethnicization reduces average winner quality for the pro-majority party with the opposite true for the minority party. The effect increases with greater numerical dominance of the majority (and so social homogeneity). Empirical evidence from a survey on politician corruption that we conducted in North India is remarkably consistent with our theoretical predictions.