Miracle-dz/UniFAR-FTUs huggingface dataset:
Self-adaptive user profiles for large-scale data delivery

Push based data delivery requires knowledge of user interests for making scheduling, bandwidth allocation, and routing decisions. Such information is maintained as user profiles. We propose a novel incremental algorithm for constructing user profiles based on monitoring and user feedback. In contrast to earlier approaches, which typically represent profiles as a single weighted interest vector, we represent user profiles as multiple interest vectors, whose number, size, and elements change adaptively based on user access behavior. This flexible approach allows the profile to more accurately represent complex user interests. Although there has been significant research on user profiles, our approach is unique in that it can be tuned to trade-off profile complexity and quality. This feature, together with its incremental nature, makes our method suitable for use in large scale information filtering applications such as push based WWW page dissemination. We evaluate the method by experimentally investigating its ability to categorize WWW pages taken from Yahoo! categories. Our results show that the method can provide high filtering effectiveness with modest profile sizes and can effectively adapt to changes in users' interests.
Tumor‐associated trypsin inhibitor in normal and malignant renal tissue and in serum of renal‐cell carcinoma patients

Tumor‐associated trypsin inhibitor (TATI) is a 6‐kDa peptide, which is identical to the pancreatic‐secretory‐trypsin inhibitor (PSTI). TATI is produced by several tumors and cancer cell lines, and is used as a serum marker for mucinous ovarian cancer. Elevated serum levels of TATI have also been observed in renal‐cell carcinoma (RCC). However, it is unclear whether the increase of serum TATI in this disease is caused by production of TATI by the tumor tissue, by the acute‐phase reaction frequently associated with cancer, or by impaired renal function. We examined the expression of TATI in malignant and histologically normal renal tissue by immunohistochemistry, in situ hybridization and reverse‐transcriptase‐polymerase‐chain reaction (RT‐PCR). Furthermore, we measured pre‐operative serum TATI levels in 21 patients with RCC. Immunohistochemically, TATI was detected in 13 of 20 histologically normal renal‐tissue samples, but not in 32 tissue samples from RCC. By RT‐PCR, TATI mRNA was detected in all of 10 histologically normal kidneys and in 6 of 11 RCCs, while in situ hybridization analysis gave negative results. Pre‐operative serum TATI was elevated in 57% of RCC patients. We also studied expression of TATI mRNA and protein in 7 renal‐cancer cell lines, by RT‐PCR and immunofluorometric assay respectively: 6 cancer cell lines were positive for TATI mRNA, while 4 of them also produced TATI protein at low levels. These results indicate that TATI is synthesized by the histologically normal renal tissue and by some renal cancers, and suggest that the elevation of serum TATI associated with renal‐cell carcinoma may be caused by the release of TATI produced by the tumor. Int. J. Cancer 83:486–490, 1999. © 1999 Wiley‐Liss, Inc.
A New Insight into Pathophysiological Mechanisms of Zinc in Diarrhea

An increasing amount of data showing the beneficial use of zinc (Zn) in treating diarrhea continues to emerge from epidemiological and clinical trials. However, without a thorough understanding of physiological mechanisms of Zn, it does not support policy recommendation to advocate the therapeutic use of Zn. Our data demonstrate that Zn is a potential antidiarrheal agent that provides substantial benefit by stimulating sodium absorption and inhibiting chloride secretion in intestinal epithelial cells. Thus, inclusion of Zn in oral rehydration solution (ORS) has the potential to markedly augment the effectiveness of ORS in the treatment of diarrhea.
FESAS: Towards a Framework for Engineering Self-Adaptive Systems

The complexity and size of information systems are growing, resulting in an increasing effort for maintenance. Self-adaptive systems (SAS) that autonomously adapt to changes in the environment or in the system itself (e.g. disfunction of components) can be a solution. So far, the development of SAS is frequently tailored to specific use case requirements. The creation of frameworks with reusable process elements and system components is often neglected. However, with such a framework developing SAS would become faster and less error prone. This work addresses this gap by providing a framework for engineering SAS.
The Earth Charter and the ESDinds Initiative

This descriptive report outlines an innovative project in which Earth Charter International is actively involved. The project aims to develop approaches, indicators and tools for Civil Society Organisations (CSOs) to be able to measure values-based aspects and impacts of their work at the project level. Many CSOs have an intuitive feeling that their projects are more successful when there is a resonance of values with those involved; this project aims to make such aspects tangible, measurable and transferable to other CSOs. The two year, EU-funded project called ESDinds is characterised by a collaborative partnership between a geographically and culturally diverse consortium consisting of four CSOs (including the Earth Charter International Secretariat) and two universities. The research design takes an iterative, grounded research approach to indicator development.
The Activity of Nodules of the Supernodulating Mutant Mtsunn Is not Limited by Photosynthesis under Optimal Growth Conditions

Legumes match the nodule number to the N demand of the plant. When a mutation in the regulatory mechanism deprives the plant of that ability, an excessive number of nodules are formed. These mutants show low productivity in the fields, mainly due to the high carbon burden caused through the necessity to supply numerous nodules. The objective of this study was to clarify whether through optimal conditions for growth and CO2 assimilation a higher nodule activity of a supernodulating mutant of Medicago truncatula (M. truncatula) can be induced. Several experimental approaches reveal that under the conditions of our experiments, the nitrogen fixation of the supernodulating mutant, designated as sunn (super numeric nodules), was not limited by photosynthesis. Higher specific nitrogen fixation activity could not be induced through short- or long-term increases in CO2 assimilation around shoots. Furthermore, a whole plant P depletion induced a decline in nitrogen fixation, however this decline did not occur significantly earlier in sunn plants, nor was it more intense compared to the wild-type. However, a distinctly different pattern of nitrogen fixation during the day/night cycles of the experiment indicates that the control of N2 fixing activity of the large number of nodules is an additional problem for the productivity of supernodulating mutants.
A Hybrid Accurate Model for Tidal Current Prediction

This paper proposes an accurate hybrid method based on support vector regression (SVR) and autoregressive integrated moving average (ARIMA) to predict the tidal current speed and direction. In the proposed hybrid model, the ARIMA model captures the linear component of the tidal current, and the remained residual components are modeled by SVR. In order to capture the maximum linear components, the appropriate order of the ARIMA model is determined by the Akaike information criterion. Autocorrelation and partial autocorrelation functions are used to verify the stationary or nonstationary characteristics of tidal data. In order to adjust the optimal values of SVR parameters, a new optimization method based on the crow search algorithm is developed to search the problem space globally. In addition, a three-phase modification method is proposed to increase the diversity of the algorithm. The proposed hybrid model is highly accurate and outperforms the artificial neural network, ARIMA, genetic algorithm, and SVR. This model is applied on the practical data collected from the Bay of Fundy, NS, Canada, in 2008.
The myogenic electric organ of Sternopygus macrurus: a non-contractile tissue with a skeletal muscle transcriptome

In most electric fish species, the electric organ (EO) derives from striated muscle cells that suppress many muscle properties. In the gymnotiform Sternopygus macrurus, mature electrocytes, the current-producing cells of the EO, do not contain sarcomeres, yet they continue to make some cytoskeletal and sarcomeric proteins and the muscle transcription factors (MTFs) that induce their expression. In order to more comprehensively examine the transcriptional regulation of genes associated with the formation and maintenance of the contractile sarcomere complex, results from expression analysis using qRT-PCR were informed by deep RNA sequencing of transcriptomes and miRNA compositions of muscle and EO tissues from adult S. macrurus. Our data show that: (1) components associated with the homeostasis of the sarcomere and sarcomere-sarcolemma linkage were transcribed in EO at levels similar to those in muscle; (2) MTF families associated with activation of the skeletal muscle program were not differentially expressed between these tissues; and (3) a set of microRNAs that are implicated in regulation of the muscle phenotype are enriched in EO. These data support the development of a unique and highly specialized non-contractile electrogenic cell that emerges from a striated phenotype and further differentiates with little modification in its transcript composition. This comprehensive analysis of parallel mRNA and miRNA profiles is not only a foundation for functional studies aimed at identifying mechanisms underlying the transcription-independent myogenic program in S. macrurus EO, but also has important implications to many vertebrate cell types that independently activate or suppress specific features of the skeletal muscle program.
The Culturally Responsive Teacher

Belki Alvarez, a young girl one of us knows, arrived in New York from the Dominican Republic several years ago with her parents and two siblings. After a difficult start in the United States, both parents found jobs; their minimum-wage earnings were barely enough for a family of five to scrape by month to month. As the oldest child in the family, Belki soon had to assume caretaking responsibilities for her younger brother and sister. At only 8 years old, she was responsible for getting her siblings ready for school, taking them there each morning, bringing them back home at the end of the school day, and caring for them until her parents came home from work.
Untrained Multiple Classifier System for designing security scanner for web applications

The Multiple Classifier Systems are nowadays one of the most promising directions in pattern recognition. There are many methods of decision making based on classifier groups. The most popular are those methods that have their origin in voting, where the decision of the common classifier is a combination of simple classifiers decisions. The paper presents an idea how a decision about attack in application layer could be made by an Intrusion Detection System application using a combining classifier. The results of the computer experiments carried out on computer-generated data, confirm quality of the proposed concept.
Interaction of Audition and Vision for the Perception of Prosodic Contrastive Focus

Prosodic contrastive focus is used to attract the listener's attention to a specific part of the utterance. Mostly conceived of as auditory/acoustic, it also has visible correlates which have been shown to be perceived. This study aimed at analyzing auditory-visual perception of prosodic focus by elaborating a paradigm enabling an auditory-visual advantage measurement (avoiding the ceiling effect) and by examining the interaction between audition and vision. A first experiment proved the efficiency of a whispered speech paradigm to measure an auditory-visual advantage for the perception of prosodic features. A second experiment used this paradigm to examine and characterize the auditory-visual perceptual processes. It combined performance assessment (focus detection score) to reaction time measurements and confirmed and extended the results from the first experiment. This study showed that adding vision to audition for perception of prosodic focus can not only improve focus detection but also reduce reaction times. A further analysis suggested that audition and vision are actually integrated for the perception of prosodic focus. Visual-only perception appeared to be facilitated for whispered speech suggesting an enhancement of visual cues in whispering. Moreover, the potential influence of the presence of facial markers on perception is discussed.
Mothers' conceptions of everyday rules for young toddlers: A longitudinal investigation.

Mothers' (Ν = 106) ratings of rules and child compliance for their young children, and the effects of child temperament and mothers' justifications for rules on ratings of rules and compliance, were examined longitudinally at 14 and 24 months. Rules for young toddlers pertained primarily to safety, safeguarding property, interpersonal issues, and, as children got older, conventions. As expected, mothers endorsed moral justifications for interpersonal rules, prudential justifications for safety and property rules, and conventional and psychological justifications for conventions. Compli ance increased significantly with age and was greater for property, safety, and inter personal behaviors than for other issues. Parent-rated child temperament and harm justifications predicted mothers' ratings of rules and child compliance, and ratings of rules, compliance, and justifications demonstrated continuity over time.
A low power and high speed Carbon Nanotube 5-to-3 compressor

Carbon Nanotube Field Effect Transistors (CNFETs) are one of the most excellent devices for low power and high performance designs. In this paper novel high speed and low power 5-to-3 compressor are presented. In a multiplication process, to accumulate partial products, compressor cells are used. Our proposed 5-to-3 compressor is simulated using HSPICE based on CNFET model with 0.9V VDD. Simulation results show that our design is faster and consumes less power compare to other design of 5-to-3 compressor with adder cells.
Infantile colic: a review

Infantile colic is characterised by episodes of uncontrollable crying or fussing in an otherwise healthy and well-fed infant less than three months of age. The episodes of crying in an infant with colic last more than three hours per day and more than three days per week for at least three weeks. The condition can be very stressful for the family. Cows’ milk proteins appear to be associated with the prevalence of infantile colic in a significant number of cases. Supportive counselling, reassurance, and dietary modifications if necessary, are the core measures used for the treatment of this condition. In most infants, infantile colic resolves by three to four months of age.
Texture sprites: texture elements splatted on surfaces

We present a new interactive method to texture complex geometries at very high resolution, while using little memory and without the need for a global planar parameterization. We rely on small texture elements, the texture sprites, locally splatted onto the surface to define a composite texture. The sprites can be arbitrarily blended to create complex surface appearances. Their attributes (position, size, texture id) can be dynamically updated, thus providing a convenient framework for interactive editing and animated textures. We demonstrate the flexibility of our method by creating new surface aspects difficult to achieve with other methods.Each sprite is described by a small set of attributes which is stored in a hierarchical structure surrounding the object's surface. The patterns supported by the sprites are stored only once. The whole data structure is compactly encoded into GPU memory. At run time, it is accessed by a fragment program which computes the final appearance of a surface point from all the sprites covering it. The overall memory cost of the structure is very low compared to the resulting texturing resolutions. Rendering is done in real-time. The resulting texture is linearly interpolated and filtered.
Expression of cell growth and bone specific genes at single cell resolution during development of bone tissue‐like organization in primary osteoblast cultures

Primary cultures of calvarial derived normal diploid osteoblasts undergo a developmental expression of genes reflecting growth, extracellular matrix maturation, and mineralization during development of multilayered nodules having a bone tissue‐like organization. Scanning electron microscopy of the developing cultures indicates the transition from the uniform distribution of cuboidal osteoblasts to multilayered nodules of smaller cells with a pronounced orientation of perinodular cells towards the apex of the nodule. Ultrastructural analysis of the nodule by transmission electron microscopy indicates that the deposition of mineral is confined to the extracellular matrix where cells appear more osteocytic. The cell body contains rough endoplasmic reticulum and golgi, while these intracellular organelles are not present in the developing cellular processes. To understand the regulation of temporally expressed genes requires an understanding of which genes are selectively expressed on a single cell basis as the bone tissue‐like organization develops. In situ hybridization analysis using 35S labelled histone gene probes, together with 3H‐thymidine labelling and autoradiography, indicate that greater than 98% of the pre‐confluent osteoblasts are proliferating. By two weeks, both the foci of multilayered cells and internodular cell regions have down‐regulated cell growth associated genes. Post‐proliferatively, but not earlier, initial expression of both osteocalcin and osteopontin are restricted to the multilayered nodules where all cells exhibit expression. While total mRNA levels for osteopontin and osteocalcin are coordinately upregulated with an increase in mineral deposition, in situ hybridization has revealed that expression of osteocalcin and osteopontin occurs predominantly in cells associated with the developing nodules. In contrast, proliferating rat osteosarcoma cells (ROS 17/2.8) concomitantly express histone H4, along with osteopontin and osteocalcin. These in situ analyses of gene expression during osteoblast growth and differentiation at the single cell level establish that a population of proliferating calvarial‐derived cells subsequently expresses osteopontin and osteocalcin in cells developing into multilayered nodules with a tissue‐like organization.
Comparative Analysis of Transcriptomes in Rhizophoraceae Provides Insights into the Origin and Adaptive Evolution of Mangrove Plants in Intertidal Environments

Mangroves are woody plants that grow at the interface between land and sea in tropical and subtropical latitudes, where they exist in conditions of high salinity, extreme tides, strong winds, high temperatures, and muddy, anaerobic soils. Rhizophoraceae is a key mangrove family, with highly developed morphological and physiological adaptations to extreme conditions. It is an ideal system for the study of the origin and adaptive evolution of mangrove plants. In this study, we characterized and comprehensively compared the transcriptomes of four mangrove species, from all four mangrove genera, as well as their closest terrestrial relative in Rhizophoraceae, using RNA-Seq. We obtained 41,936–48,845 unigenes with N50 values of 982–1,185 bp and 61.42–69.48% annotated for the five species in Rhizophoraceae. Orthology annotations of Gene Ontology, Kyoto Encyclopedia of Genes and Genomes, and Clusters of Orthologous Groups revealed overall similarities in the transcriptome profiles among the five species, whereas enrichment analysis identified remarkable genomic characteristics that are conserved across the four mangrove species but differ from their terrestrial relative. Based on 1,816 identified orthologs, phylogeny analysis and divergence time estimation revealed a single origin for mangrove species in Rhizophoraceae, which diverged from the terrestrial lineage ~56.4 million years ago (Mya), suggesting that the transgression during the Paleocene–Eocene Thermal Maximum may have been responsible for the entry of the mangrove lineage of Rhizophoraceae into intertidal environments. Evidence showed that the ancestor of Rhizophoraceae may have experienced a whole genome duplication event ~74.6 Mya, which may have increased the adaptability and survival chances of Rhizophoraceae during and following the Cretaceous–Tertiary extinction. The analysis of positive selection identified 10 positively selected genes from the ancestor branch of Rhizophoraceae mangroves, which were mainly associated with stress response, embryo development, and regulation of gene expression. Positive selection of these genes may be crucial for increasing the capability of stress tolerance (i.e., defense against salt and oxidative stress) and development of adaptive traits (i.e., vivipary) of Rhizophoraceae mangroves, and thus plays an important role in their adaptation to the stressful intertidal environments.
El papel de la evaluación formativa en el proceso de convergencia hacia el E.E.E.S. Análisis del estado de la cuestión y presentación de un sistema de intervención

El proceso de Convergencia hacia el EEES implica una serie de cambios en la forma de entender y organizar la docencia universitaria, tanto en lo referente a la metodologia de ensenanza y aprendizaje como a la evaluativa. En este articulo planteamos la necesidad de avanzar hacia modelos de evaluacion mas coherentes con dichos planteamientos. Un aspecto importante de este nuevo modelo es la participacion del alumnado en los procesos de evaluacion. Tras una primera introduccion, realizamos una serie de aclaraciones terminologicas sobre la tematica. Posteriormente revisamos el estado de la cuestion, incluyendo un breve analisis sobre las diferencias existentes entre el portafolios y la carpeta, y presentamos nuestra propuesta de evaluacion para la docencia universitaria, que denominamos Evaluacion Formativa y Compartida. A continuacion realizamos una revision de los puntos fuertes y debiles que hemos encontrado durante los once anos que llevamos poniendo en practica este sistema de evaluacion. Junto a los puntos debiles planteamos una serie de posibles estrategias para intentar superarlos. Por ultimo, presentamos las principales conclusiones del trabajo.
PENGARUH KUALITAS LAYANAN TERHADAP KEPUASAN DAN WOM (STUDI DI RSUD WANGAYA DENPASAR)

ABSTRAK Kemampuan untuk memberikan kualitas layanan yang dapat memenuhi harapan pasien merupakan strategi yang sangat penting untuk mencapai keunggulan kompetitif. Tujuan dari penelitian ini adalah untuk mengetahui pengaruh dari kualitas layanan terhadap kepuasan dan komunikasi word of mouth (WOM) pada pasien rawat inap di Paviliun Praja Amerta RSUD Wangaya. Populasi dalam penelitian ini adalah semua pasien yang pernah menjalani rawat inap di Paviliun Praja Amerta RSUD Wangaya. Metode penentuan sampel dilakukan dengan metode purposive sampling dengan jumlah responden sebanyak 150 responden. Pengujian hipotesis penelitian dengan menggunakan analisis Structural Equation Modeling (SEM). Hasil penelitian menunjukkan bahwa kualitas layanan berpengaruh positif dan signifikan terhadap kepuasan. , Kualitas layanan berpengaruh positif dan signifikan terhadap WOM, dan Kepuasan berpengaruh positif dan signifikan terhadap WOM. Kata Kunci : Kualitas Layanan, Kepuasan, Pasien, WOM