Miracle-dz/UniFAR-FTUs huggingface dataset:
Synchronized Incidental Affect Changes Ambiguity Preferences

Abstract Decisions under uncertainty are prevalent, but come under two distinct types. Risk, which has unknown outcomes but known probabilities for those outcomes and ambiguity which contains both unknown outcomes and unknown probabilities. Although there have been several studies linking affect and aversion to ambiguity, there have been no studies that have to identify how changing one’s affective response can change their choices. A total of 166 adults ( M = 36.54, SD = 11.80) participated in an online study through Prolific. Participants were presented with a lottery on each trial which varied on its uncertainty type (risky vs ambiguous) and winning characteristics (winning probability and amount). Half of the ambiguous lotteries were paired with an neutral image (e.g., office supplies), while the other half was paired with an emotionally evocative image (e.g., burning house) that was hypothesized to incidentally influence their decisions. As measured by both raw choice data as well as through a computational model, participants were more averse to ambiguity when the lottery was paired with an emotionally evocative image. Follow-up analyses revealed that only lotteries in which the computational model predicted the participant would choose the lottery were affected by the images. This study highlights the phenomenon in which one’s awareness of an affective stimulus can alter its impact on their decisions.
Expansion of the split hygromycin toolkit for transgene insertion in Caenorhabditis elegans

Engineered sites for genetic transformation have simplified transgene insertion in Caenorhabditis elegans . These strategies include our split hygromycin system (Stevenson et al. 2020) which allows for integration-specific selection of transgenes. Here we have expanded the split hygromycin selection system to include two additional chromosomal locations, both of which are permissive for germline expression, as well as engineered landing pads in three additional natural isolates. Corresponding guide and empty repair template plasmids are also available for each of these sites.
Microphase Separation Produces Interfacial Environment within Diblock Biomolecular Condensates

The phase separation of intrinsically disordered proteins is emerging as an important mechanism for cellular organization. However, efforts to connect protein sequences to the physical properties of condensates, i.e., the molecular grammar, are hampered by a lack of effective approaches for probing high-resolution structural details. Using a combination of multiscale simulations and fluorescence lifetime imaging microscopy experiments, we systematically explored a series of systems consisting of diblock elastin-like polypeptides (ELP). The simulations succeeded in reproducing the variation of condensate stability upon amino acid substitution and revealed different microenvironments within a single condensate, which we verified with environmentally sensitive fluorophores. The interspersion of hydrophilic and hydrophobic residues and a lack of secondary structure formation result in an interfacial environment, which explains both the strong correlation between ELP condensate stability and interfacial hydrophobicity scales, as well as the prevalence of protein-water hydrogen bonds. Our study uncovers new mechanisms for condensate stability and organization that may be broadly applicable.
The Effect of Osthole on Transient Receptor Potential Channels: A Possible Alternative Therapy for Atopic Dermatitis

Introduction Chronic recurrent skin inflammation and severe itching in patients with atopic dermatitis (AD) significantly impair their quality of life. The H4 histamine receptor plays a key role in histamine-induced itching. During the skin inflammation associated with AD, pro-inflammatory mediators (interleukins, cytokines) are released from neurons. Ultimately, a cascade of reactions leads to the activation and sensitization of transient receptor potential channels (TRP), which exacerbate the inflammation and itching associated with AD. Osthole (OST) is a natural coumarin with a proven versatile pharmacological effect: anti-cancer, anti-inflammatory and immunomodulatory. However, the molecular mechanism of OST in relieving inflammation in histamine-mediated itching is not yet clear. Purpose In the studies presented, the possible effect of the OST action on the inhibition of the gene expression of the histamine H4 receptor and the key genes of the TRP channels as well as on the concentration of proinflammatory interleukins was analyzed. Methods Inflammation was induced in a 3D skin model and a keratinocyte cell line Normal Human Epidermal Keratinocytes (NHEK) identical to that of AD, and then OST was administered at various doses. The concentrations of IL-4/-13 were determined by ELISA. RNA was isolated from the 3D skin cells and the NHEK cell line, and the qPCR method was used to determine the expression of: IL-4α, H4R, TRPV1, TRPV4, TRPM8 analyzed. Results The study showed that OST significantly reduced the secretion of IL-4/-13 in a keratinocyte cell line and in a 3D skin model. In addition, OST was found to significantly decrease the gene expression of IL-4α, H4R, TRPV1, TRPV4 and increase TRPM8 in both the NHEK cell line and the organotypic 3D skin model. Conclusion The data obtained provide the first in vitro evidence of itch relief following the application of OST to atopic skin. Research on the use of OST as an active component of emollients in the treatment of AD should be continued in the future.
Embodied navigation: the influence of lived experience on physical activity and sedentary behavior among older adults

ABSTRACT Purpose The impact of a sedentary lifestyle on health and well-being is well recognized. However, there is limited understanding of how a lifetime of physical activity and sedentary behaviour influences an active lifestyle in older adults. The aim of this study was to describe how lived experience of physical activity and sedentary behaviour impacts daily activities among older adults, from a life course perspective. Methods Qualitative content analysis was used; individual telephone interviews were conducted with fourteen older adults aged 71 to 92 years. The participants received initial support from community care and lived in ordinary housing in southern Sweden. Results The interviews yielded one theme, “Navigating with an embodied activity compass,” and two sub-themes: “Being guided by the past” and “Unveiling pathways through body awareness. ” Conclusions Our study highlights how older adults’ lived experiences of physical activity, with their connections to body awareness and acceptance, impact daily physical activity. These findings offer new knowledge for clinical practitioners balancing recommendations of sedentary behaviour and physical activity, to promote healthy daily physical activity among older adults. Future research and policies should consider the lived experiences of older adults when addressing public health matters related to sedentary behaviour and physical activity.
Mainland Chinese Tourist Behavior and Motivations: Evidence from Two Destinations in Southern Thailand

With more than 70 million Chinese travelers annually, China has recently become the top outbound tourism of the world. This study, therefore, examine Chinese tourists regarding their experience of travelling in Thailand to gain a better understanding of Chinese’s tourist behavior and identify the motivational factors that significantly influence their decision to take a trip to Thailand. The finding of this study shows that top three motivation factors that pull Chinese high-value tourists to visit Thailand are beautiful beaches and natural attractions by cultural festival and events and good value for money. Family and/or friends and travel agents are the important players in travel decision making. Lastly, the study reveals that the majority of the research participants have intention to re-visit Thailand as well as making recommendation and sharing their experiences with others.
Wireless Body Area Nanonetworks via Vascular Molecular Communication

Advancements in biotechnology and molecular communication have enabled the utilization of nanomachines in Wireless Body Area Networks (WBAN2) for applications such as drug delivery, cancer detection, and emergency rescue services. To study these networks effectively, it is essential to develop an ideal propagation model that includes the channel response between each pair of in-range nanomachines and accounts for the interference received at each receiver node. In this paper, we employ an advection-diffusion equation to obtain a deterministic channel matrix through a vascular WBAN2. Additionally, the closed forms of inter-symbol interference (ISI) and co-channel interference (CCI) are derived for both full duplex (FDX) and half duplex transmission (HDX) modes. By applying these deterministic formulations, we then present the stochastic equivalents of the ideal channel model and interference to provide an innovative communication model by simultaneously incorporating CCI, ISI, and background noise. Finally, we evaluate the results with numerous experiments and use signal-to-interference-plus-noise ratio (SINR) and capacity as metrics.
Taxonomic significance of morphological and elemental characteristics of achenes of Artemisia genus from Turkey.

In the study, the achene macromorphological and micromorphological characters of the genus Artemisia distributed in Turkey have been researched with the target of knowing systematically important carpological structures for the examined species. Macro-morphological structures of the achenes including color, shape, dimension, and carpopodium diameter were studied with 100 achenes of 10 specimens per taxa with a Light Microscope. Micro-morphological features of the achenes containing surface ornamentation, anticlinal and periclinal cell walls, epidermal cells, and the presence of secondary structures were examined with a Scanning Electron Microscope. EDS analyses were performed with a SEM. EDS analyses were carried out by selecting the same spot on the sample surface at 80 sec under 30 μm aperture size, with 20 kV acceleration voltage, 8 mm operating distance, high current, and processing time conditions. The color, shape, and dimension of achene have macro-morphologically shown variations. The examined achenes are separated into four shapes; fusiform-oblong, oblong, oblong-ovate, and ovate. Oblong-ovate is the most common type. Achene dimensions range from 0.62 to 2.48 mm in length, and from 0.30 to 1.21 mm in width. Also, carpopodium diameter varies between 0.10 and 0.19 mm. Achene surfaces of the examined taxa are micro-morphologically assessed, and substantial differences are noticeably detected on behalf of the surface structures for instance, surface ornamentation, anticlinal and periclinal cell walls, epidermal cells, and the presence of secondary structures of the achenes. Surface ornamentation is separated into 10 types: irregularly sulcate, regularly sulcate, ruminate, sulcate-scalariform, rugose, favulariate, slightly sulcate, alveolate, tuberculate, and reticulate. A percentage comparison of the elements in the achene pericarp of the studied taxa has been performed with SEM-EDS. Accordingly, pericarps in taxa include C, Ca, K, Mg, Cl, Si, Na, and S elements. In the taxonomy of the genus Artemisia, the achene morphological characters are very significant characteristics that disclose inter-specific relations among the examined taxa. Moreover, a dichotomous key is offered for the identification of the studied taxa based on achene characters. RESEARCH HIGHLIGHTS: The achenes of Turkish Artemisia taxa have been examined in depth. The morphological characteristics of achenes of Turkish Artemisia taxa have been studied using SEM and LM for the first time and debated the systematic practice of these characters. The elemental content of the achene pericarp has been systematically evaluated for the first time.
Very long-period data from the geoscope network: Preliminary results on great circle averages of fundamental and higher Rayleigh and Love modes

Abstract We have analyzed the long-period Rayleigh and Love waves that were generated by four recent large earthquakes (New Ireland of 18 March 1983; Costa Rica of 4 April 1983; Honshu of 26 May 1983; and Chagos Islands of 30 November 1983). Our records are those of the three-component very long-period stations (SSB, PCR, PAF, and TAM) of the GEOSCOPE network, that were in operation in 1983. Available information from transverse and radial components is obtained; preliminary results concerning the fundamental modes of Love and Rayleigh waves, the first toroidal overtone, the second, and the third spheroidal higher mode are presented. For each of these particular modes, the phase velocities and sometimes the Q quality factors have been obtained, and the methods of data reduction are described in detail for future reference. The examples shown demonstrate, in particular, the benefits to be expected from a modern three-component very long-period network, as well as from original station locations.
Evolutionary trade-offs between testes size and parenting in Neotropical glassfrogs

In males, large testes size signifies high sperm production and is commonly linked to heightened sperm competition levels. It may also evolve as a response to an elevated risk of sperm depletion due to multiple mating or large clutch sizes. Conversely, weapons, mate or clutch guarding may allow individuals to monopolize mating events and preclude sperm competition, thereby reducing the selection of large testes. Herein, we examined how paternal care, sexual size dimorphism (SSD), weaponry and female fecundity are linked to testes size in glassfrogs. We found that paternal care was associated with a reduction in relative testes size, suggesting an evolutionary trade-off between testes size and parenting. Although females were slightly larger than males and species with paternal care tended to have larger clutches, there was no significant relationship between SSD, clutch size and relative testes size. These findings suggest that the evolution of testes size in glassfrogs is influenced by sperm competition risk, rather than sperm depletion risk. We infer that clutch guarding precludes the risk of fertilization by other males and consequently diminishes selective pressure for larger testes. Our study highlights the prominent role of paternal care in the evolution of testes size in species with external fertilization.
Analisis Indeks Kekeringan Menggunakan Metode Thornthwaite Mather Pada DAS Siak

The level of risk of drought in the DAS Siak can be known, by calculating the index for drought using Thornthwaite Mather method. This method emphasizes the importance of rainfall data as input and potential evapotranspiration as superficial, but it is also necessary parameters soil moisture and vegetation as listener. The relationship between rainfall and potential evapotranspiration shows the state of the showing period of drought month and and the wet month. In the drought month period the amount of rain water is not sufficient for the water used by the plant, resulting in a shortage of soil moisture. The relationship between soil moisture shortage by potential evapotranspiration yield drought index. The choice of location DAS Siak in this study in order to reinforce the Drought Disaster Risk Index Map Riau Province issued by BNPB. Climate variability analysis results showed a decrease in the average annual rainfall of 15.50 mm/yr and an increase in average annual temperature of 0.08 °C. Thornthwaite Mather method analysis results showed an increase in average drought of 3.99% every year. The highest level of risk of drought occurred in 2014 and 2015 with a duration of severe drought occurred from January to November.
Preparing healthcare leaders of the digital age with an integrative artificial intelligence curriculum: a pilot study

ABSTRACT Artificial intelligence (AI) is rapidly being introduced into the clinical workflow of many specialties. Despite the need to train physicians who understand the utility and implications of AI and mitigate a growing skills gap, no established consensus exists on how to best introduce AI concepts to medical students during preclinical training. This study examined the effectiveness of a pilot Digital Health Scholars (DHS) non-credit enrichment elective that paralleled the Dartmouth Geisel School of Medicine’s first-year preclinical curriculum with a focus on introducing AI algorithms and their applications in the concurrently occurring systems-blocks. From September 2022 to March 2023, ten self-selected first-year students enrolled in the elective curriculum run in parallel with four existing curricular blocks (Immunology, Hematology, Cardiology, and Pulmonology). Each DHS block consisted of a journal club, a live-coding demonstration, and an integration session led by a researcher in that field. Students’ confidence in explaining the content objectives (high-level knowledge, implications, and limitations of AI) was measured before and after each block and compared using Mann-Whitney U tests. Students reported significant increases in confidence in describing the content objectives after all four blocks (Immunology: U = 4.5, p = 0.030; Hematology: U = 1.0, p = 0.009; Cardiology: U = 4.0, p = 0.019; Pulmonology: U = 4.0, p = 0.030) as well as an average overall satisfaction level of 4.29/5 in rating the curriculum content. Our study demonstrates that a digital health enrichment elective that runs in parallel to an institution’s preclinical curriculum and embeds AI concepts into relevant clinical topics can enhance students’ confidence in describing the content objectives that pertain to high-level algorithmic understanding, implications, and limitations of the studied models. Building on this elective curricular design, further studies with a larger enrollment can help determine the most effective approach in preparing future physicians for the AI-enhanced clinical workflow.
Recent climatological trends and potential influences on forest phenology around western Lake Superior, USA

We assess long‐term climatological means, trends, and interannual variability around the western end of Lake Superior during 1984–2013 by using available weather station data. Our results focus on changes in basic and derived climate indicators from seasonal and annual temperature and precipitation, to the traditionally defined frost‐free season, to a novel definition of the climatological growing season. We describe seasonal and year‐to‐year climate variability that influences forest phenology, using an alternative growing season metric that is based on the warm‐season plateau in accumulated chilling days as an indicator of environmental triggers for vegetation growth and senescence. Our results indicate +0.56°C regional warming during our 30 year study period, with cooler springs (−1.26°C) and significant autumn warming (+1.54°C). The duration of the climatological growing season has increased +0.27 d/yr, extending primarily into autumn. Summer precipitation in our study area has declined by an average −0.34 cm/yr, potentially leading to moisture stress that impairs vegetation carbon uptake rates and can render the forest more vulnerable to disturbance. Many changes in temperature, precipitation, and climatological growing season are most prominent in locations where Lake Superior exerts a strong hydroclimatological influence, especially the Minnesota shoreline and in forest areas downwind (southeast) of the lake. Observed trends in lake temperature and ice phenology have also changed, coincident with a large‐scale climatological regime shift around 1998. A number of factors are likely altering forest phenology and the role of the forest in the climate system of this ecologically important and highly varied forest‐and‐lake region.
Spatio-temporal registration in augmented reality

Feng Zheng: Spatio-Temporal Registration in Augmented Reality (Under the direction of Gregory F. Welch) The overarching goal of Augmented Reality (AR) is to provide users with the illusion that virtual and real objects coexist indistinguishably in the same space. An effective persistent illusion requires accurate registration between the real and the virtual objects, registration that is spatially and temporally coherent. However, visible misregistration can be caused by many inherent error sources, such as errors in calibration, tracking, and modeling, and system delay. This dissertation focuses on new methods that could be considered part of “the last mile” of spatio-temporal registration in AR: closed-loop spatial registration and low-latency temporal registration: 1. For spatial registration, the primary insight is that calibration, tracking and modeling are means to an end—the ultimate goal is registration. In this spirit I present a novel pixel-wise closed-loop registration approach that can automatically minimize registration errors using a reference model comprised of the real scene model and the desired virtual augmentations. Registration errors are minimized in both global world space via camera pose refinement, and local screen space via pixel-wise adjustments. This approach is presented in the context of Video See-Through AR (VST-AR) and projector-based Spatial AR (SAR), where registration results are measurable using a commodity color camera. 2. For temporal registration, the primary insight is that the real-virtual relationships are evolving throughout the tracking, rendering, scanout, and display steps, and registration can be improved by leveraging fine-grained processing and display mechanisms. In this spirit I introduce a general end-to-end system pipeline with low latency, and propose an
Evaluating transpiration from Pinus sylvestris var. mongolica and Caragana microphylla using sap flow method

Sap flow rates were determined using sap flow methods in August,2006 from a 20-year-old mixed plantation of Pinus sylvestris var.mongolica and Caragana microphylla at a sandy site located in the Horqin Region of northeastern China.Sap flow rates were then used to estimate transpiration of individual trees based on their sapwood areas and leaf areas.Furthermore, the relationship between water use and soil moisture dynamics was also analyzed.The results showed that variations in transpirations of both tree species were significantly related to the changes in photosynthetically active radiation and vapor pressure deficit.The transpiration rates for P.sylvestris var.mongolica showed a declining trend over the study period,ranging from 0.21 to 1.17 mm per day with an average value of 0.81 mm per day.The transpiration from C.microphylla was relatively high and stable in semi-arid environment,and its daily transpiration values were 0.51-2.79 mm per day,with an average of 1.98 mm per day.The total transpiration from the mixed forest in August amounted to 86.5 mm,which represented 137.7% of the precipitation over the same period.