Miracle-dz/UniFAR-FTUs huggingface dataset:
The effect of Uncertainty of dental implant morphology on osseointegration

Dental implants have attracted significant attention and been well accepted as the most effective treatment to partially or fully edentulous patients, among which osseointegrated dental implants have a great potential to achieve desirable and predictable outcomes [1]. In order to further increase success rate of implantation and reduce healing time, an improved osseointegration quality is believed to be achieved by porous-coated morphology. A 18 month trial has been conducted on a partially porous-coated endosseous dental implant with traditional threads, and the histological data clearly indicated a shortened stabilizing time of implantation and dramatically increased contact area over all porous-coated samples to threaded ones [2]. To model such a scenario, we applied multi-scale finite element analysis technique to a 2D dental implant model over a 48 month remodelling process, where the displacement responses from a macro-scale model was transferred to the localized micro-scale model with detailed porous surface morphology characteristics [3, 4]. However, this piece of work was based upon a deterministic model of coating and particles/beads in the micro model and did not capture the random feature of coating process.
Geomagnetic disturbance storm system impact — A transmission facility owner case study

Federal Energy Regulatory Commission (FERC) Order No. 830 (September 2016) delivered a mandate for reliable transmission system performance during geomagnetic disturbance (GMD) events. In this Order, FERC approved the North American Electric Reliability Corporation (NERC) reliability standard TPL-007-1 (Transmission System Planned Performance for Geomagnetic Disturbance Events). This paper presents the results and conclusions of a transmission facility owner (TFO) system case study. For it, a geomagnetically induced current (GIC) model was developed for a major part of the Alberta Interconnected Electric System (AIES). The main objectives of the study were identifying the transformers most susceptible to high levels of GIC flows and estimating the additional reactive power support to the induced half-cycle saturation triggered by GMD events. Also investigated were: steady-state system security during a GMD event; the need to undertake further studies to more fully investigate GMD event risks; and the need to consider other system components when doing so. The results and conclusions of the study provide a transmission planning approach that complies with NERC TPL-007-1.
Design of a Smart Ultrasonic Transducer for Interconnecting Machine Applications

A high-frequency ultrasonic transducer for copper or gold wire bonding has been designed, analyzed, prototyped and tested. Modeling techniques were used in the design phase and a practical design procedure was established and used. The transducer was decomposed into its elementary components. For each component, an initial design was obtained with simulations using a finite elements model (FEM). Simulated ultrasonic modules were built and characterized experimentally through the Laser Doppler Vibrometer (LDV) and electrical resonance spectra. Compared with experimental data, the FEM could be iteratively adjusted and updated. Having achieved a remarkably highly-predictive FEM of the whole transducer, the design parameters could be tuned for the desired applications, then the transducer is fixed on the wire bonder with a complete holder clamping was calculated by the FEM. The approach to mount ultrasonic transducers on wire bonding machines also is of major importance for wire bonding in modern electronic packaging. The presented method can lead to obtaining a nearly complete decoupling clamper design of the transducer to the wire bonder.
How Distance Affects Semantic Integration in Discourse: Evidence from Event-Related Potentials

Event-related potentials were used to investigate whether semantic integration in discourse is influenced by the number of intervening sentences between the endpoints of integration. Readers read discourses in which the last sentence contained a critical word that was either congruent or incongruent with the information introduced in the first sentence. Furthermore, for the short discourses, the first and last sentence were intervened by only one sentence while for the long discourses, they were intervened by three sentences. We found that the incongruent words elicited an N400 effect for both the short and long discourses. However, a P600 effect was only observed for the long discourses, but not for the short ones. These results suggest that although readers can successfully integrate upcoming words into the existing discourse representation, the effort required for this integration process is modulated by the number of intervening sentences. Thus, discourse distance as measured by the number of intervening sentences should be taken as an important factor for semantic integration in discourse.
Real time multiple people tracking and pose estimation

In this paper we present a combined probability estimation approach to detect and track multiple people for pose estimation at the same time. It can deal with partial and total occlusion between persons by adding torso appearance to the tracker. Moreover, the upper body of each individual is further segmented into head, torso, upper arm and lower arm in a hierarchical way. The simplicity of the feature and the simplified model allow close real time performance of the tracker. The experimental results show that the proposed method can deal with most of the inner-occlusion between persons, as well as certain self-occlusion. It's also much faster than the existing methods with comparable accuracy.
The medical‐care cost burden of obesity

Recent years have seen a dramatic rise in the prevalence of obesity in many countries, stimulating interest in the health and economic consequences of this phenomenon. In this article, we provide a systematic review of the literature on the medical‐care cost burden of obesity. Relevant studies were identified using a computerized search of the medical literature for English‐language articles published between 1990 and 2001. The 18 studies that met all criteria for inclusion in the review can be classified as modelling or database studies and further distinguished as cross‐sectional or longitudinal in nature. The majority of studies that have been conducted are cross‐sectional modelling studies, including 10 studies reporting the burden of obesity to national health systems. These suggest that obesity accounts for 5.5–7.0% of national health expenditures in the United States and 2.0–3.5% in other countries for which estimates have been reported. Other studies highlight the burden of obesity from other perspectives, including employers and health plans, as well as the impact of obesity on future disease risks and associated medical‐care costs. Despite various methodological limitations, discussed herein, this body of research leads to the inescapable conclusion that obesity exacts an immense economic toll in various countries throughout the world.
VELO: A Novel Communication Engine for Ultra-Low Latency Message Transfers

This paper presents a novel stateless, virtualized communication engine for sub-microsecond latency. Using a field-programmable-gate-array (FPGA) based prototype we show a latency of 970 ns between two machines with our virtualized engine for low overhead (VELO). The FPGA device is directly connected to the CPUs by a hypertransport link. The described hardware architecture is optimized for small messages and avoids the overhead typically found with direct-memory access (DMA) controlled transfers. The stateless approach allows to use the hardware unit directly from many threads and processes simultaneously. It provides a secure user level communication with an extremely optimized start-up phase. Micro benchmarks results are reported both based on proprietary API and OpenMPI basis.
Coronary Artery Disease Risk in Familial Combined Hyperlipidemia and Familial Hypertriglyceridemia: A Case-Control Comparison From the National Heart, Lung, and Blood Institute Family Heart Study

Background—Conventional wisdom suggests that a diagnosis of familial combined hyperlipidemia (FCHL) carries a substantially greater risk of premature coronary artery disease (CAD) than a diagnosis of familial hypertriglyceridemia (FHTG). However, no population-based studies have critically addressed this issue. Methods and Results—FCHL and FHTG were diagnosed in 10.2% and 12.3% of 334 random control families and in 16.7% and 20.5% of 293 families with at least one case of premature CAD. The diagnosis of either FCHL or FHTG in an individual was associated with an odds ratio for CAD of 2.0 (P =0.003 and 0.002, respectively). However, odds ratios for premature CAD associated with both lipid disorders decreased substantially and identically with further adjustment for hypertension, diabetes, and especially HDL cholesterol, triglycerides, or apolipoprotein B. Similar results were found for differences in carotid intima-medial thickness and ankle-brachial index. Metabolic syndrome was identified in 65% of FCHL and 71% of FHTG patients compared with 19% in controls without FCHL or FHTG and was associated with an odds ratio of 3.3 (P <0.0001). The increased prevalence of the metabolic syndrome alone could account for the elevated CAD risk associated with both FCHL and FHTG. Conclusions—FCHL and FHTG appear more alike than dissimilar. Further, the risk of CAD in FCHL and FHTG was strongly related to features of the metabolic syndrome. These findings suggest that the hypertriglyceridemia in FHTG is not benign and may warrant a change in epidemiological, genetic, and clinical approaches to these lipid disorders.
Decreased Peak Muscle Power is Associated with Motor Unit Loss in the Lower Limb of Older Adults

This study investigated the relationship between motor unit (MU) properties and the strength and power of two lower limb muscles in healthy young and old adults. Twelve older adults (mean age, 77 ± 5 yrs) and twelve young adults (mean age, 24 ± 3 yrs) were studied. MU properties of the tibialis anterior (TA) and vastus medialis (VM) muscles were determined using decomposition-enhanced spike-triggered averaging (DE-STA). Motor unit number estimates (MUNE) of the TA were significantly reduced (p>0.05) in older adults (102 ± 76) compared to young adults (234 ± 109), primarily as a result of significantly larger surface-detected motor unit potentials (S-MUP) in older adults. Although VM S-MUP values were larger in older adults (60 ± 31 μV) compared to young (48 ±42), the difference was not significant. Maximal strength and power were significantly larger in both the TA and knee extensors of young adults compared to old. Maximal power output displayed greater deficits than isometric strength in both lower limb muscles of older adults. Results from this study indicate that there are changes in MU properties with age, and that this effect may be greater in the TA muscle. Further, power, especially in the knee extensors, may be a more sensitive measure of neuromuscular health than isometric strength, and should be the focus of exercise programs in elderly subjects.
Mass and angular momenta of Kerr anti-de Sitter spacetimes in Einstein–Gauss–Bonnet theory

We compute the mass and angular momenta of rotating anti-de Sitter spacetimes in Einstein–Gauss–Bonnet theory of gravity using a superpotential derived from standard Nœther identities. The calculation relies on the fact that the Einstein and Einstein–Gauss–Bonnet vacuum equations are the same when linearized on maximally symmetric backgrounds and uses the recently discovered D-dimensional Kerr–anti-de Sitter solutions to Einstein's equations.
New Insights into Neutrophil Extracellular Traps: Mechanisms of Formation and Role in Inflammation

Recent data suggest that NETosis plays a crucial role in the innate immune response and disturbs the homeostasis of the immune system. NETosis is a form of neutrophil-specific cell death characterized by the release of large web-like structures referred to as neutrophil extracellular traps (NETs). NETs are composed of DNA strands associated with histones and decorated with about 20 different proteins, including neutrophil elastase, myeloperoxidase, cathepsin G, proteinase 3, high mobility group protein B1, and LL37. Reportedly, NETosis can be induced by several microbes, and particulate matter including sterile stimuli, via distinct cellular mechanisms. Meanwhile, suicidal NETosis and vital NETosis are controversial. As we enter the second decade of research on NETosis, we have partly understood NETs as double-edged swords of innate immunity. In this review, we will discuss the mechanisms of NETosis, its antimicrobial action, and role in autoimmune diseases, as well as the relatively new field of NET-associated mitochondrial DNA.
Diagnostic tests for Alzheimer disease: FDG-PET imaging is a player in search of a role.

[Graphic][1] Imaging with [18F]fluorodeoxyglucose-positron emission tomography (FDG-PET) offers excellent insights into regional brain dysfunction but fails to deliver tangible benefits in most clinical settings in persons with suspected cognitive impairment. The radiation exposure from a single FDG-PET brain scan is 1.3 rem, equivalent to about 3 chest X-rays or 4 months of background radiation; therefore, while unnecessary exposure to radiation is to be avoided, my view is not driven by risks of PET scanning. It is the realities of clinical diagnostics and the lack of potent interventions for specific dementing illnesses that limit the value of FDG-PET. Diagnoses of mild cognitive impairment (MCI) or dementia are entirely based on information obtained from the history and cognitive examination. Distinguishing abnormal cognition from normal cognition can sometimes be very challenging. As clinicians, we are often confronted with patients who report cognitive complaints that seem discordant with their level of daily functioning. Because there is a wide range of what is considered normal based on education, occupation, and cultural background, and because mood or motivation issues sometimes cloud performance, the distinction between normal and impaired can be very difficult. An FDG-PET scan will not solve this problem. The availability of FDG-PET offers a seductive but flawed logic that goes something like this: “Even though I don't know clinically whether the person has cognitive impairment or not, an abnormal FDG-PET would confirm that the cognitive complaints … [1]: /embed/inline-graphic-1.gif
The Open University ’ s repository of research publications and other research outputs Semantic metrics

In the context of the Semantic Web, many ontology-related operations, e.g. ontology ranking, segmentation, alignment, articulation, reuse, evaluation, can be boiled down to one fundamental operation: computing the similarity and/or dissimilarity among ontological entities, and in some cases among ontologies themselves. In this paper, we review standard metrics for computing distance measures and we propose a series of semantic metrics. We give a formal account of semantic metrics drawn from a variety of research disciplines, and enrich them with semantics based on standard Description Logic constructs. We argue that concept-based metrics can be aggregated to produce numeric distances at ontology-level and we speculate for the usability of our ideas through application example areas.
2010 update of the ASAS/EULAR recommendations for the management of ankylosing spondylitis

This first update of the ASAS/EULAR recommendations on the management of ankylosing spondylitis (AS) is based on the original paper, a systematic review of existing recommendations and the literature since 2005 and the discussion and agreement among 21 international experts, 2 patients and 2 physiotherapists in a meeting in February 2010. Each original bullet point was discussed in detail and reworded if necessary. Decisions on new recommendations were made — if necessary after voting. The strength of the recommendations (SOR) was scored on an 11-point numerical rating scale after the meeting by email. These recommendations apply to patients of all ages that fulfill the modified NY criteria for AS, independent of extra-articular manifestations, and they take into account all drug and non-drug interventions related to AS. Four overarching principles were introduced, implying that one bullet has been moved to this section. There are now 11 bullet points including 2 new ones, one related to extra-articular manifestations and one to changes in the disease course. With a mean score of 9.1 (range 8-10) the SOR was generally very good.
Reaching out to older veterans in need: the Elko clinic demonstration project.

CONTEXT The challenge of providing meaningful health care services to veterans living in rural communities is a major public health concern that involves redefining the traditional facility-based model of care delivery employed in urban areas. PURPOSE This paper describes the steps of a demonstration project, the Elko Telehealth Outreach Clinic. The clinic, located in Elko, Nevada, was created to meet the health care needs of veterans who expressed a desire for greater access to VA services. METHODS The Elko Telehealth Outreach Clinic is a specific example of the real-life implementation of the community-as-partner model as an operational framework for coordinating local, regional, and VA resources. The Elko Clinic provides a limited set of health care services including medication management, health education, prescription refills, routine lab tests, and specialty services through telehealth. FINDINGS From December 2006 to December 2007, a total of 84 unique veterans received health care services through the Elko Clinic. CONCLUSIONS Our findings support the usefulness of an expanded community-as-partner model to guide a process for addressing the health care needs of veterans in Elko, Nevada, and they have implications for the development and maintenance of outreach clinics in other rural settings.
Automatic lip localization and feature extraction for lip-reading

In recent year, lip-reading systems have received a great attention, since it plays an important role in human communication with computer especially for hearing impaired or elderly people. The need for an automatic lip-reading system is ever increasing. Today, extraction and reliable analysis of facial movements make up an important part in many multimedia systems such as videoconference, low communication systems, lipreading systems. We can imagine, for example, a dependent person ordering a machine with an easy lip movement or by a simple syllable pronunciation. We present in this paper a new approach for lip localization and feature extraction in a speaker’s face. The extracted visual information is then classified in order to recognize the uttered viseme (visual phoneme). To check our system performance we have developed our Automatic Lip Feature Extraction prototype (ALiFE). Experiments revealed that our system recognizes 70.95 % of French digits uttered under natural conditions.
Gender Separation and Mating Constraints

This paper presents a model for simulating various reproduction modes and types restrictions from nature with the genetic algorithms. We consider three reproduction modes, which are self-fertilizing, hermaphrodite excluding self fertilization, and with two differentiated gender types (male and female). We start with a model in which the reproduction mode evolves along with the rest of the genotype. Next, we compare the performance of the reproduction modes we have introduced and study the influence of the population size on their performance. Finally, we introduce some mating restrictions similar to the natural geographical and social limitations and study their influence on the performance of each reproduction mode.
Student perceptions regarding classroom environments for learning

STUDENT PERCEPTIONS REGARDING CLASSROOM ENVIRONMENTS FOR LEARNING MAY 2002 JEAN E. GREENWOOD, B.A., CLARK UNIVERSITY M.Ed., FITCHBURG STATE COLLEGE Ed.D. , UNIVERSITY OF MASSACHUSETTS AMHERST Directed by: Professor Robert L. Sinclair The classroom environment has a powerful influence on learning, and children’s perceptions of that environment influence their behavior. This study examines the perceptions of sixth grade students who are the most and least academically successful regarding how they perceive their classroom environment and those factors within it that enhance or inhibit learning. Data gathered in this research indicate that there are significant disparities in how the most and least successful students perceive their classroom learning environment. The most successful students perceived the classroom environment as more affiliative and task focused, perceived their teachers to be more trusting, caring, and supportive, and perceived that they had more choice in how they learned. In contrast, the least successful students perceived the class to be more teacher controlled and competitive. In spite of the differences in friendship and support perceived by study participants, both groups of students were able to provide clear examples of teaching approaches and classroom conditions that they perceived increased or inhibited their learning. This study also includes students’ suggestions for changes that would increase their learning. The findings in this study are consistent with the research and literature
Palliative surgery for advanced stage (stage IV) gastric adenocarcinoma.

BACKGROUND/AIMS The factors that effect resectability, major morbidity, early mortality, and survival in advanced stage gastric adenocarcinoma patients are evaluated. METHODOLOGY Records of 74 patients that underwent surgery for stage IV gastric adenocarcinoma in the Third Surgical Clinic of Izmir Atatürk Training Hospital between January 1997 and January 2004 were reviewed retrospectively. Two groups (the patients with resectable disease and those with unresectable disease) were compared with regard to age, gender, primary complaint, symptoms, site of the tumor, involvement of adjacent organs, lymph node involvement, distant metastases, differentiation of tumor, surgical procedure, perioperative blood transfusions, and postoperative hospital stay. RESULTS Mean age of the 74 patients was 58.4 years. Forty-five cases (60.8%) were considered as unresectable and 29 (39.2%) patients underwent a palliative resection. There was a significant relation between resectability and site of the tumor, and severity of invasion. As the number of perioperative blood transfusions increased, morbidity and mortality increased significantly. Although early mortality was high in the palliative resection group, survival (mean 10.4 months, longest 25 months) was better compared to that of the unresectable gastric cancer group (mean 3.5 months, longest eight months). CONCLUSIONS A palliative gastric surgery may be applied to improve prognosis of advanced gastric cancer patients, even at the presence of peritoneal dissemination, hepatic metastases, N3 lymph node involvement, adjacent organ invasion, or poor differentiation of the tumor.