Miracle-dz/UniFAR-FTUs huggingface dataset:
University choice: what do we know, what don’t we know and what do we still need to find out?

– The purpose of this paper is to systematically document, scrutinise and critically analyse the current research literature on higher education choice to: establish the scope of the studies; map the factors associated with choice; identify the key strengths and weaknesses in the research literature; critically analyse the extant research and make recommendations for further research in this field. , – The authors conducted extensive searches of relevant and education and management databases. The search is limited to publications between 1992 and 2013 and is intended to cover national and international research. The review is based on 75 papers which focus on institutional choice, assembled on an Excel database (45 surveys, 13 secondary data studies, one experimental study, two longitudinal studies, 11 qualitative studies and three studies that use both qualitative and quantitative techniques). , – Results are presented under thematic headings which emerged from the analysis: first, demographics and academic factors; second, factors which relate to the institution: quality, outcomes and benefits, facilities, and characteristics of institutions. Finally factors which affect both the institution and the students: price and price sensitivity, information and information sources, and travel and geographical factors are considered. , – Comprehensive analysis of prior research in the field of institutional choice is long overdue. Theoretical models for future research are presented as a result of the findings.
Application of User-Based Collaborative Filtering Recommendation Technology on Logistics Platform

With the rapid development of logistics industry, there are lots of logistics service and tons of data emerging on logistics platform. To match service and customers better, personalized recommendations logistics services is needed. In this paper, we introduce a collaborative filtering technology of e-commerce personalized recommendation system into the logistics platform. We present the application of the technology in the logistics platform step by step. Finally, we conduct a numerical example to illustrate the use of the technology proposed in this paper.
Genetic determined low response to thienopyridines is associated with higher systemic inflammation in smokers.

AIM To investigate whether the interactions of CYP2C19*2 and CYP2C19*17 with smoking are associated with the levels of P2Y12 receptor inhibition and CRP, in on-thienopyridine post-stenting patients. METHODS & RESULTS At 1-month follow-up, the interactions of smoking and CYP2C19 polymorphisms on the vasodilator-stimulated phosphoprotein - platelet reactivity index (VASP PRI), and CRP were explored in three metabolizing groups (1128 patients) as follow: poor metabolizers (*2 carriers/*17 noncarriers); intermediate metabolizers (*2 carriers/*17 carriers or *2 noncarriers/*17 noncarriers); and ultrarapidmetabolizers (*2 allele noncarriers/*17 carriers). The interactions of metabolizing status and smoking was significant for CRP (p = 0.001) but not for VASP PRI (p = 0.734). CONCLUSION Interaction between CYP2C19 polymorphisms and smoking modifies on-treatment CRP level of post-stenting, on-thienopyridine patients. This effect seems to be independent to the level of P2Y12 receptor inhibition.
Misogyny, Dionysianism and a new model of Greek tragedy

The subject of misogyny in Greek culture is widely recognized as of capital importance in understanding our attitude towards women as well as the general culture context within which that attitude is framed. Yet despite the obvious importance of this subject there has been little attention given to the way misogyny in fifth‐centry Athens was an integral part of its greatest art form, the tragic drama. Only when a model of tragedy is developed which accounts for the typological opposition between the male “tragic hero” and Dionysus will it be possible to understand how women function within this particular literary genre as the essential “other” of repressive male consciousness.
Epidermal Growth Factor Receptor Blockade Mediates Smooth Muscle Cell Apoptosis and Improves Survival in Rats With Pulmonary Hypertension

Background—We previously reported that administration of elastase inhibitors reverses fatal pulmonary arterial hypertension (PAH) in rats by inducing smooth muscle cell (SMC) apoptosis. We showed in pulmonary artery (PA) organ culture that the mechanism by which elastase inhibitors induce SMC apoptosis involves repression of matrix metalloproteinase (MMP) activity and subsequent signaling through &agr;v&bgr;3-integrins and epidermal growth factor receptors (EGFRs). This suggests that blockade of these downstream effectors may also induce regression of PAH. Methods and Results—In this study, we first showed in PA organ culture that MMP inhibition or &agr;v&bgr;3-integrin blockade with agents in clinical and preclinical use (SC-080 and cilengitide, respectively) mediates SMC apoptosis and regression of medial hypertrophy. We also documented similar results with an EGFR tyrosine kinase inhibitor. We then induced PAH in rats by injection of monocrotaline and, at day 21, began a 2-week treatment with SC-080, cilengitide, or the EGFR inhibitor PKI166. No vehicle- or cilengitide-treated animal survived beyond 2 weeks. Administration of SC-080 resulted in 44% survival at 2 weeks, and PKI166 therapy resulted in 78% and 54% survival in daily or 3-times-weekly treated animals, respectively. Four weeks after cessation of PKI166, we documented survivals of 50% and 23% in the 2 treatment groups, associated with reductions in pulmonary pressure, right ventricular hypertrophy, and abnormally muscularized distal arteries. Conclusion—We propose that selective blockade of EGFR signaling may be a novel strategy to reverse progressive, fatal PAH.
Inclusion in Norway: a study of ideology in practice

The purpose of this research was to examine how Norway's ideology of inclusion is realized in Norwegian schools and school systems, and what factors work to support or hinder its implementation. Using semi-structured interviews, we obtained data from our informants at multiple levels in the Norwegian educational system in one municipality. Our data analyses focused on identifying themes that were shared by multiple informants, as well as retaining important points or perspectives from individuals. Generally all of the informants were positive towards the ideology of inclusion. The biggest difficulty facing its implementation seemed to be that of social integration. This was much more of a concern than curricular integration. Probably because of such challenges, schools still placed students in separate settings. Factors that affected inclusion included: characteristics of teachers, classroom environment, school climate, cooperation, support from people with competence, attitudes and resources.
Chinese Conflict Preferences and Negotiating Behaviour: Cultural and Psychological Influences

This paper analyzes the extent to which both traditional Chinese cultural values and Chinese psychology influence Chinese perceptions and approaches to conflict resolution and thus affect Chinese negotiating behaviour. An attempt is made to illustrate salient cultural values and orientations, and empirical data is used to identify Chinese conflict preferences. The extent to which both these cultural values and conflict preferences have shaped a distinctive Chinese negotiation style is then examined.
The millennium generation: Teacher-researchers exploring new forms of literacy

This article describes a collaborative teacher-researcher project exploring how 4—8-year-old children understood and worked with new forms of literacy at home and at school. Twenty-five teacher-researchers investigated young children’s home based multimodal funds of knowledge and then planned school or preschool curriculum based on these findings. The project revealed that children, independent of geographic location, had access to and could use information technologies far in advance of teachers’ expectations and had access to equipment beyond that available in many of the schools and preschools. In response to children’s use of and engagement with new literacies the teacher-researchers developed a framework known as the Multiliteracies Map. This framework was used in a state-wide early years professional learning programme to support curriculum planning for new forms of literacy. The teacher-researchers became the facilitators of the professional learning programme that took place in local districts and regions. A case study of one teacher-researcher shows how this literacy framework was used to plan and assess children’s learning with new forms of literacy.
“Love ya, jerkface”: Using Sparse Log-Linear Models to Build Positive and Impolite Relationships with Teens

One challenge of implementing spoken dialogue systems for long-term interaction is how to adapt the dialogue as user and system become more familiar. We believe this challenge includes evoking and signaling aspects of long-term relationships such as rapport. For tutoring systems, this may additionally require knowing how relationships are signaled among non-adult users. We therefore investigate conversational strategies used by teenagers in peer tutoring dialogues, and how these strategies function differently among friends or strangers. In particular, we use annotated and automatically extracted linguistic devices to predict impoliteness and positivity in the next turn. To take into account the sparse nature of these features in real data we use models including Lasso, ridge estimator, and elastic net. We evaluate the predictive power of our models under various settings, and compare our sparse models with standard non-sparse solutions. Our experiments demonstrate that our models are more accurate than non-sparse models quantitatively, and that teens use unexpected kinds of language to do relationship work such as signaling rapport, but friends and strangers, tutors and tutees, carry out this work in quite different ways from one another.
Guest Editors' Introduction

Taylor & Francis makes every effort to ensure the accuracy of all the information (the “Content”) contained in the publications on our platform. However, Taylor & Francis, our agents, and our licensors make no representations or warranties whatsoever as to the accuracy, completeness, or suitability for any purpose of the Content. Any opinions and views expressed in this publication are the opinions and views of the authors, and are not the views of or endorsed by Taylor & Francis. The accuracy of the Content should not be relied upon and should be independently verified with primary sources of information. Taylor and Francis shall not be liable for any losses, actions, claims, proceedings, demands, costs, expenses, damages, and other liabilities whatsoever or howsoever caused arising directly or indirectly in connection with, in relation to or arising out of the use of the Content.
ON THE CONSTRUCTION OF STRONG CIPHERS FROM WEAK ONES

In this paper we show how one can construct "strong" ciphers from weak ones. The proposed constructions give the designer a flexibility to control both the key and the input sizes and also to control the amount of work needed by an analyst to recover the key or the plaintext. This is of importance in providing a flexible high level security designs needed for securing a variety of systems and applications without going into the subtle details of designing new ciphers and the lengthy process of scrutiny and certification.
Road blocks on paleogenomes—polymerase extension profiling reveals the frequency of blocking lesions in ancient DNA

Although the last few years have seen great progress in DNA sequence retrieval from fossil specimens, some of the characteristics of ancient DNA remain poorly understood. This is particularly true for blocking lesions, i.e. chemical alterations that cannot be bypassed by DNA polymerases and thus prevent amplification and subsequent sequencing of affected molecules. Some studies have concluded that the vast majority of ancient DNA molecules carry blocking lesions, suggesting that the removal, repair or bypass of blocking lesions might dramatically increase both the time depth and geographical range of specimens available for ancient DNA analysis. However, previous studies used very indirect detection methods that did not provide conclusive estimates on the frequency of blocking lesions in endogenous ancient DNA. We developed a new method, polymerase extension profiling (PEP), that directly reveals occurrences of polymerase stalling on DNA templates. By sequencing thousands of single primer extension products using PEP methodology, we have for the first time directly identified blocking lesions in ancient DNA on a single molecule level. Although we found clear evidence for blocking lesions in three out of four ancient samples, no more than 40% of the molecules were affected in any of the samples, indicating that such modifications are far less frequent in ancient DNA than previously thought.
Organizational context and firm‐level entrepreneurship: a multiple‐case analysis

Purpose – The purpose of this paper is to understand firm‐level entrepreneurship in diverse organizational contexts and explain its relationship with organizational factors.Design/methodology/approach – The paper adopts a multiple‐case research design. In‐depth interviews are conducted with key informants in four cases. In each case, a firm‐level entrepreneurial story is focused on to understand the entrepreneurial process within its organizational context.Findings – The findings show that there are two types of entrepreneurial activities in organizations – beyond‐boundary focus and within‐boundary focus. They exhibit different patterns regarding their relationship with organizational factors – top management leadership, strategic orientation, organizational culture, internal mechanisms and organizational performance.Research limitations/implications – Generalizability of the results may be limited due to the case study design of this research.Practical implications – Top management leadership has a vital.
Dual LMI approach to H∞ performance limitation analysis of sensitivity and complementary sensitivity functions

In this paper, we study a dual-LMI-based approach to H∞ performance limitation analysis of SISO systems. The scope includes the analysis of the sensitivity function S = (1 + PK)-1 and the complementary sensitivity function T = (1 + PK)-1 PK where P and K stand for the plant and the controller, respectively. The H∞ performance limitations for these transfer functions are well investigated, and exact closed-form performance bounds are already known for the cases where the plant has the sole unstable zero (i.e., non-minimum phase zero) of degree one or the sole unstable pole of degree one. The goal of this paper is to show that such exact bounds can be reproduced by a dual LMI approach. To this end, we study a Lagrange dual of the standard SDP that is usually used to design H∞ optimal controllers by numerical computation. By characterizing the structure of dual feasible solutions in terms of unstable zeros and unstable poles of the plant, we clarify that we can construct an optimal solution for the dual SDP analytically. It follows that we obtain exact H∞ performance bounds that are consistent with the known results.
The dopamine patchwork of the rat nucleus accumbens core

The dopamine (DA) terminal field in the rat dorsal striatum is organized as a patchwork of domains that show distinct DA kinetics. The rate and short‐term plasticity of evoked DA release, the rate of DA clearance and the actions of several dopaminergic drugs are all domain‐dependent. The patchwork arises in part from local variations in the basal extracellular concentration of DA, which establishes an autoinhibitory tone in slow but not fast domains. The present study addressed the hypothesis that a domain patchwork might also exist in the nucleus accumbens core (NAcc), a DA terminal field that is deeply involved in reward processing and the mechanisms underlying substance abuse. DA recordings in the NAcc by fast‐scan voltammetry during electrical stimulation of the medial forebrain bundle confirmed that the NAcc contains a patchwork of fast and slow domains showing significantly different rates of evoked DA release and DA clearance. Moreover, the NAcc domains are substantially different from those in the dorsal striatum. There were no signs in the NAcc of short‐term plasticity of DA release during multiple consecutive stimuli, and no signs of a domain‐dependent autoinhibitory tone. Thus, the NAcc domains are distinct from each other and from the domains of the dorsal striatum.
Machine learning methods for prediction of disulphide bonding states of cysteine residues in proteins

The goal of this thesis work is to develop a computational method based on machine learning techniques for predicting disulfide-bonding states of cysteine residues in proteins, which is a sub-problem of a bigger and yet unsolved problem of protein structure prediction. Improvement in the prediction of disulfide bonding states of cysteine residues will help in putting a constraint in the three dimensional (3D) space of the respective protein structure, and thus will eventually help in the prediction of 3D structure of proteins. Results of this work will have direct implications in site-directed mutational studies of proteins, proteins engineering and the problem of protein folding. We have used a combination of Artificial Neural Network (ANN) and Hidden Markov Model (HMM), the so-called Hidden Neural Network (HNN) as a machine learning technique to develop our prediction method. By using different global and local features of proteins (specifically profiles, parity of cysteine residues, average cysteine conservation, correlated mutation, sub-cellular localization, and signal peptide) as inputs and considering Eukaryotes and Prokaryotes separately we have reached to a remarkable accuracy of 94% on cysteine basis for both Eukaryotic and Prokaryotic datasets, and an accuracy of 90% and 93% on protein basis for Eukaryotic dataset and Prokaryotic dataset respectively. These accuracies are best so far ever reached by any existing prediction methods, and thus our prediction method has outperformed all the previously developed approaches and therefore is more reliable. Most interesting part of this thesis work is the differences in the prediction performances of Eukaryotes and Prokaryotes at the basic level of input coding when ‘profile’ information was given as input to our prediction method. And one of the reasons for this we discover is the difference in the amino acid composition of the local environment of bonded and free cysteine residues in Eukaryotes and Prokaryotes. Eukaryotic bonded cysteine examples have a ‘symmetric-cysteine-rich’ environment, where as Prokaryotic bonded examples lack it.
Chemotaxis signaling protein CheY binds to the rotor protein FliN to control the direction of flagellar rotation in Escherichia coli

The direction of rotation of the Escherichia coli flagellum is controlled by an assembly called the switch complex formed from multiple subunits of the proteins FliG, FliM, and FliN. Structurally, the switch complex corresponds to a drum-shaped feature at the bottom of the basal body, termed the C-ring. Stimulus-regulated reversals in flagellar motor rotation are the basis for directed movement such as chemotaxis. In E. coli, the motors turn counterclockwise (CCW) in their default state, allowing the several filaments on a cell to join together in a bundle and propel the cell smoothly forward. In response to the chemotaxis signaling molecule phospho-CheY (CheYP), the motors can switch to clockwise (CW) rotation, causing dissociation of the filament bundle and reorientation of the cell. CheYP has previously been shown to bind to a conserved segment near the N terminus of FliM. Here, we show that this interaction serves to capture CheYP and that the switch to CW rotation involves the subsequent interaction of CheYP with FliN. FliN is located at the bottom of the C-ring, in close association with the C-terminal domain of FliM (FliMC), and the switch to CW rotation has been shown to involve relative movement of FliN and FliMC. Using a recently developed structural model for the FliN/FliMC array, and the CheYP-binding site here identified on FliN, we propose a mechanism by which CheYP binding could induce the conformational switch to CW rotation.
Determining isotopic life history trajectories using bone density fractionation and stable isotope measurements: a new approach.

A number of recent studies have attempted to trace diet at different stages of an individual's life by comparing isotope ratios of bone from different gross anatomical sites within the skeleton. In this study we develop this approach further by separating bone of differing mineral densities within one skeletal element, where each density fraction represents a different period of time. Isotope ratios are measured for these fractions. Each density fraction represents a period of bone formation and maturation, where younger (more recently formed) bone is less well-mineralized and therefore less dense than relatively older packets of bone. In an adult, bone is therefore able to partition approximately the last 15 years of life. Bone fractions were recovered by stepped ultracentrifugation in a series of organic solvents of increasing density, and then collagen was recovered by decalcification in dilute acid, and stable carbon isotope ratios ((13)C/(12)C) were measured. Bone density microstructure was checked for bacterial remodelling using backscattered electron imaging in a scanning electron microscope. Our results indicate that the bone density fractionation method is applicable to archaeological material, here extending to a maximum of 5,000 years BP, and that collagen can successfully be extracted from such fractions. The carbon isotope values for bone fractions of different densities patterned out as expected in one modern control bone and in specimens from five archaeological human skeletons, including three precolonial hunter-gatherers and two 18th/19th century individuals. The latter two are known (from previous assessments) to have undergone marked changes in diet during their lifetimes. Postmortem alteration was evident in some of the specimens examined. The bone density fractionation approach has allowed greater resolution of diet than has hitherto been possible and has provided access to the elusive last years and months of an individual's life.
Reverse graded relaxed buffers for high Ge content SiGe virtual substrates

An innovative approach is proposed for epitaxial growth of high Ge content, relaxed Si1−xGex buffer layers on a Si(001) substrate. The advantages of the technique are demonstrated by growing such structures via chemical vapor deposition and their characterization. Relaxed Ge is first grown on the substrate followed by the reverse grading approach to reach a final buffer composition of 0.78. The optimized buffer structure is only 2. 8μm thick and demonstrates a low surface threading dislocation density of 4×106cm−2, with a surface roughness of 2.6nm. The buffers demonstrate a relaxation of up to 107%.
How to Reduce School Bullying

Abstract A systematic review was conducted of the 30 largest and highest quality controlled evaluations of antibullying programs. Most programs were effective. The prevalence of bullying and being bullied was reduced by an average of 20–23% in experimental schools compared to control schools. The most important program elements associated with a decrease in bullying and victimization were identified. A system for accrediting effective antibullying programs in schools was recommended.