Miracle-dz/UniFAR-FTUs huggingface dataset:
Optimization of high‐molecular‐weight polycyclic aromatic hydrocarbons‘ degradation in a two‐liquid‐phase bioreactor

A microbial consortium degrading the high‐molecular‐weight polycyclic aromatic hydrocarbons (HMW PAHs) pyrene, chrysene, benzo[a]pyrene and perylene in a two‐liquid‐phase reactor was studied. The highest PAH‐degrading activity was observed with silicone oil as the water‐immiscible phase; 2,2,4,4,6,8,8‐heptamethylnonane, paraffin oil, hexadecane and corn oil were much less, or not efficient in improving PAH degradation by the consortium. Addition of surfactants (Triton X‐100, Witconol SN70, Brij 35 and rhamnolipids) or Inipol EAP22 did not promote PAH biodegradation. Rhamnolipids had an inhibitory effect. Addition of salicylate, benzoate, 1‐hydroxy‐2‐naphtoic acid or catechol did not increase the PAH‐degrading activity of the consortium, but the addition of low‐molecular‐weight (LMW) PAHs such as naphthalene and phenanthrene did. In these conditions, the degradation rates were 27 mg l−1 d−1 for pyrene, 8·9 mg l−1 d−1 for chrysene, 1·8 mg l−1 d−1 for benzo[a]pyrene and 0·37 mg l−1 d−1 for perylene. Micro‐organisms from the interface were slightly more effective in degrading PAHs than those from the aqueous phase.
Effect of Ethanolic Extract of Indigofera tinctoria on Chemically-Induced Seizures and Brain GABA Levels in Albino Rats

Objective(s) Indigofera tinctoria Linn. of Fabaceae family is claimed to be useful to control epileptic seizures in the Indian system of folkore medicine. This study was designed to evaluate tinctoria and to verify the claim. Materials and Methods Seizures were induced in male albino rats with pentylenetetrazole (PTZ). The test group animals were administered ethanolic extract of Indigofera tinctoria (EEIT) orally. The time of onset and duration of clonic convulsions were recorded. Maximal electroshock seizures (MES) were induced in animals. The duration of hind limb tonic extension (HLTE) was recorded. GABA levels and GABA transaminase activity in brain were estimated. Results In PTZ model, EEIT significantly (P< 0.01, P< 0.001) delayed the onset of convulsions and reduced the duration of seizures in a dose dependent manner. A significant (P< 0.05) reduction in the duration of HLTE at higher doses of EEIT was observed in MES model. Increase in brain GABA levels was observed on treatment with EEIT at 500 and 1000 mg/kg doses, suggested that the plant may be acting by facilitating GABAergic transmission. A significant reduction (P< 0.05) in the activity of brain GABA transaminase was observed at higher doses. No neurotoxic signs were observed with rotarod test, pentobarbital induced sleeping time, locomotor activity and haloperidol-induced catalepsy. Conclusion The ethanolic extract of tinctoria was found to be useful to control and treat the variety of seizures.
The Empirical Testing of Harter's Self-Concept Matrix on Female Adult Students

This research aimed at testing an hypothetical matrix to be used for the study of self-concept development within a life-span perspective. Following data categorization collected from 111 female university students, a significant relationship was found between structural levels and content dimensions, demonstrating a linear form of development. Also several content dimensions were often used in subjects' self-definitions, illustrating the multidimensional aspect of such development in adults.
Crystal structure of the phosphatidylinositol 3 , 4-bisphosphate-binding pleckstrin homology ( PH ) domain of tandem PH-domain-containing protein 1 ( TAPP 1 ) : molecular basis of lipid specificity

Phosphatidylinositol 3,4,5-trisphosphate [PtdIns(3,4,5)P $ ] and its immediate breakdown product PtdIns(3,4)P # function as second messengers in growth factorand insulin-induced signalling pathways. One of the ways that these 3-phosphoinositides are known to regulate downstream signalling events is by attracting proteins that possess specific PtdIns-binding pleckstrin homology (PH) domains to the plasma membrane. Many of these proteins, such as protein kinase B, phosphoinositide-dependent kinase 1 and the dual adaptor for phosphotyrosine and 3phosphoinositides (DAPP1) interact with both PtdIns(3,4,5)P $ and PtdIns(3,4)P # with similar affinity. Recently, a new PHdomain-containing protein, termed tandem PH-domain-containing protein (TAPP) 1, was described which is the first protein reported to bind PtdIns(3,4)P # specifically. Here we describe the crystal structure of the PtdIns(3,4)P # -binding PH domain of
A fruitless upstream region that defines the species specificity in the male-specific muscle patterning in Drosophila

Abstract The muscle of Lawrence (MOL) is a male-specific muscle present in the abdomen of some adult Drosophila species. Formation of the MOL depends on innervation by motoneurons that express fruitless, a neural male determinant. Drosophila melanogaster males carry a pair of MOLs in the 5th abdominal segment, whereas D. subobscura males carry a pair in both the 5th and 4th segments. We hypothesized that the fru gene of D. subobscura but not that of D. melanogaster contains a cis element that directs the formation of the additional pair of MOLs. Successively extended 5’ DNA fragments to the P1 promoter of D. subobscura or the corresponding fragments that are chimeric (i.e., containing both melanogaster and subobscura elements) were introduced into D. melanogaster and tested for their ability to induce the MOL to locate the hypothetical cis element. We found that a 1.5–2-kb genomic fragment located 4–6-kb upstream of the P1 promoter in D. subobscura but not that of D. melanogaster permits MOL formation in females, provided this fragment is grafted to the distal ∼4-kb segment from D. melanogaster, demonstrating that this genomic fragment of D. subobscura contains a cis element for the MOL induction.
THE PHYSIOLOGICAL RESPONSE TO AN AUDITORY CUE INDICATING TIME REMAINING ON A COGNITIVE PERFORMANCE TASK

Previous studies have demonstrated that time constrained tasks lead to an increase in the physiological stress response and that elevated stress levels lead to poorer performance (Wahlstrom et al, 2002) (Clark et al, 1998). It remains unknown whether the practice of professors reminding students of remaining time on examinations could be leading to poorer performance. This study is investigating whether constant verbal reminders of the time remaining to complete a cognitive task leads to a greater physiological stress response and poorer performance than the control group. Thirty-two participants were recruited from Physiology 435 at UW Madison and randomly assigned to a control and experimental group. The participants were seated and baseline MAP and heart rate were collected, and the electrodermal activity (EDA) finger monitors were attached. The control group was told they had five minutes to complete the task and was then not disturbed for the remainder of the cognitive test. The experimental group, however, was notified of the time remaining in intervals until the five minutes expired. Statistical analysis found no significance for heart rate, blood pressure, and EDA between the control and experimental groups. Regarding performance on the word search, the data were significant with the experimental group finding an average of 5.44 words and the control finding an average of 7.25 words (p=0.0357). Increasing the authenticity of the exam setup and initial screening of participants are discussed as factors that may improve future studies.
Sample Rate Conversion Using B-Spline Interpolation for OFDM Based Software Defined Radios

This paper proposes arbitrary ratio sample rate conversion (SRC) architectures and a simpler B-spline interpolation algorithm for orthogonal frequency division multiplexing (OFDM) based software defined radios (SDRs) with multiband and multi-channel capabilities. Different from conventional standalone digital front-end designs for SDRs, the proposed SRC architectures combine the B-spline interpolation with OFDM modulation and equalization for OFDM transmitter and receiver respectively. With this combined design, the passband droop introduced by the B-spline interpolation can be more efficiently compensated using frequency-domain pre-distortion, instead of conventional time-domain pre-filtering, and hence an overall system complexity reduction is achieved. A novel multi-period B-spline interpolation and re-sampling structure is then constructed, and an interpolation algorithm with lower implementation complexity than that of the conventional Farrow structure is further developed. The SRC performance is also analysed by deriving the signal-to-peak distortion ratio formulas which can be used as design tools for determining the required orders of B-splines in the OFDM transmitter and receiver respectively. Finally, SRC examples used in a high-speed multiband multi-channel microwave backhaul system are given and compared with conventional polyphase filterbank interpolation to demonstrate the practicality and performance of the proposed SRC architectures and interpolation algorithm.
An application of particle swarm optimization to the tracking of faulty lines for the monitoring of outer-race bearing faults

In this paper we focus our attention on the tracking of faulty lines emerging in the stator current in an induction motor. The defect retained is the appearance of a problem of outer race fault in ball bearings. To do that, a particle swarm optimization algorithm is used in order to track these faulty lines. Consequently, we would be able to inform the operator on the presence or not of a defect thanks to this approach. This one is easy to implement and does not required a huge calculation process. Results and methodology illustrate the efficiency of this type of approach.
Psychological treatment of PTSD in children: an evidence-based review

This paper reviews the recent literature on psychological treatments for childhood post-traumatic stress disorder and evaluates them in light of the level of evidence supporting their effectiveness. The authors examine an array of Cognitive-Behavioural treatments, including Trauma-Focused Cognitive-Behavioural Therapy (TF-CBT), eye movement desensitization and reprocessing (EMDR) and Group-Delivered Cognitive-Behavioural Therapies (GD-CBT), and also a number of other approaches. The paper concludes that the strongest evidence supports the use of TF-CBT for a wide range of ages and traumas. EMDR is also well supported. Group CBT therapies also have some support especially in response to community-wide traumatic events. A number of other approaches, including some emerging therapies, are identified as meriting further research, whereas others are seen to have little evidence supporting their effectiveness. It identifies that one common approach, critical incident stress debriefing, has little support and ma.
The neurology of olfaction

CH Hawkes, RL Doty. Published by Cambridge University Press Cambridge 2009 244 978-0-521-68216-9 The olfactory system is a phylogenetically old system that is connected to brain structures implicated in memory formation and motivational aspects of behaviour. Not surprisingly, odours can provoke vivid memories of past experiences coupled with intense emotions. The importance of olfaction to human beings is emphasised by the evolutionary conservation of a large number of genes dedicated to odour perception. In daily life, odours are essential to nutrition, safety, social interactions and our general sense of well being. Since the identification of odorant receptor genes by Linda Buck and Richard Axel in 1991, for which they were awarded the Nobel prize in Physiology or Medicine in 2004, giant leaps have been made in the understanding of the …
A dual-topology ICPT applied to an electric vehicle battery charger

In many applications, it can be useful transferring energy from a power supply to the load without any physical link. Such a solution can avoid corrosion, waterproofness problems on the one hand. And can help simplifying mechanical design on the other hand. Furthermore, it increases security level making the plugging of the cable useless, especially for high voltage transmission. This can been achieved with an inductive coupler power transfer (ICPT). In most applications, the transformer is loaded by a linear resistance. Thus, in order to recharge batteries, a converter is usually placed at the secondary side to manage battery load profile (a first step at constant current and a second one at constant voltage). The paper discusses a new method allowing the generation of this profile from the primary side. In order to achieve this goal, two compensation topologies are used.
Sexueller Dimorphismus des menschlichen Gehirns - eine Literaturübersicht

: Some findings of neurobiological brain research regarding structural sex differences of the human brain are reviewed and discussed. Besides the well known difference in brain size, especially some cell groups of the hypothalamus display differences between the sexes. The results obtained for other regions, such as the corpus callosum and other commissural systems, are inconclusive. Further dimorphisms involve the temporal lobes and sex-specific brain asymmetry. These differences seem to be subtle and are superimposed by high interindividual variability. Finally, little morphological support is found for behavioural differences between the sexes.
Selective Phenotyping for Increased Efficiency in Genetic Mapping Studies

The power of a genetic mapping study depends on the heritability of the trait, the number of individuals included in the analysis, and the genetic dissimilarity among them. In experiments that involve microarrays or other complex physiological assays, phenotyping can be expensive and time-consuming and may impose limits on the sample size. A random selection of individuals may not provide sufficient power to detect linkage until a large sample size is reached. We present an algorithm for selecting a subset of individuals solely on the basis of genotype data that can achieve substantial improvements in sensitivity compared to a random sample of the same size. The selective phenotyping method involves preferentially selecting individuals to maximize their genotypic dissimilarity. Selective phenotyping is most effective when prior knowledge of genetic architecture allows us to focus on specific genetic regions. However, it can also provide modest improvements in efficiency when applied on a whole-genome basis. Importantly, selective phenotyping does not reduce the efficiency of mapping as compared to a random sample in regions that are not considered in the selection process. In contrast to selective genotyping, inferences based solely on a selectively phenotyped population of individuals are representative of the whole population. The substantial improvement introduced by selective phenotyping is particularly useful when phenotyping is difficult or costly and thus limits the sample size in a genetic mapping study.
Six independent factors of personality variation: a response to Saucier

We address the concerns raised by Saucier about our proposed six‐factor structure of personality. First, we dispute Saucier's new interpretation of the Negative Valence factor as a meaningful dimension of personality variation. We explain that Negative Valence terms may distort the structure of personality‐descriptive terms, and that the substantive variance of Honesty is weakly correlated with Negative Valence. Also, we point out that our proposed six factors are (like the Big Five) roughly orthogonal, and that the occurrence of rotational variants within this six‐dimensional space is not problematic. We argue that in terms of comprehensiveness, parsimony, independence of factors, and replicability across languages, our proposed six‐factor model so far seems to be the optimal structure of personality characteristics. Copyright © 2002 John Wiley & Sons, Ltd.
The Corporate Family: Theory and Treatment.

The authors define characteristics of a corporate family style of functioning. An emphasis is placed on the need for sensitivity to the value structure of the family. Crisis is seen coming from a disruption in the support system of one or more members of the family. A treatment strategy with a case illustration is introduced based on strengthening the family using natural coping mechanisms in the community. The objective of treatment is to reinforce the family without necessarily challenging their values or style of functioning.
The Kore: My Experiences with the Maiden Archetype

An exploration of the living reality of the psyche, this article shows how the ancient Greek myth of Demeter and Persephone is unconsciously incarnated in the 20th-century life of the author as a young woman. Beginning with a numinous childhood dream, she describes her experiences of being possessed by the autonomous archetype of the Kore, how the possession guided her psychological development and influenced her early career as a dancer. Following in the footsteps of the myth, she considers the positive impact of Hades’ rape of the Kore, especially as it impacts the development of the animus in a woman. The struggle to establish a healing relationship with Demeter in the face of a deeply negative personal mother complex leads her back to the dance studio for active imagination in movement that releases the transcendent function within her body and in synchronous events in her world.
Affiliation Tendencies on the Eve of the Iraqi War: A Utility Theory Perspective

Affiliation tendencies among 212 Israeli children and their parents were examined in January to March 2003, when the prospect for an Iraqi attack against Israel was high. Based on utility theory (Rofe, 1984), it was hypothesized that Israeli citizens would prefer the company of less anxious others, rather than those with similar and higher levels of anxiety. Additionally, it was expected that subjects would be less inclined to talk about war-related issues since their need for cognitive clarity was already satisfied by the mass media. This study also compared the affiliation and discussion tendencies of children and adults. Results were consistent with utility theory and demonstrated its theoretical value in accounting for affiliation tendencies in stressful situations.
An Adaptive Clustering Approach for the Diversification of Image Retrieval Results

In this paper, we explore the application of an adaptive clustering approach for the diversification of image retrieval results in the context of the MediaEval 2016 Retrieving Diverse Social Images Task. The proposed approach exploits available textual descriptions, the visual content of the images, and a set of common clustering techniques to select the best combination for each image query individually and in an unsupervised manner.
Investigation of the substrate specificity of a cloned expressed human bilirubin UDP-glucuronosyltransferase: UDP-sugar specificity and involvement in steroid and xenobiotic glucuronidation.

A cloned human bilirubin UDP-glucuronosyltransferase (UGT) stably expressed in Chinese hamster V79 cells was used to assess the substrate specificity of the enzyme. The catalytic potential (Vmax/Km(bilirubin) of the enzyme with UDP-glucuronic acid (UDPGA) was 2-fold and 10-fold greater than that for UDP-xylose and UDP-glucose respectively. The formation of bilirubin mono- and di-conjugates was found to be dependent on time, UDP-sugar concentration and bilirubin concentration. Ex vivo studies demonstrated that the genetically engineered cell line was capable of the uptake and glucuronidation of bilirubin and the release of bilirubin glucuronide, indicating its usefulness in studying transport processes. Over 100 compounds, including drugs, xenobiotics and endogenous steroids, were tested as substrates for the enzyme to determine the chemical structures accepted as substrates. A wide diversity of xenobiotic compounds such as phenols, anthraquinones and flavones (many of which are in foodstuffs) were glucuronidated by the enzyme. The enzyme also had the capacity to glucuronidate oestriols and oestradiols stereoselectively. H.p.l.c. analysis of the regioselective glucuronidation of beta-oestradiol (E2) demonstrated that it was conjugated solely at its A-ring hydroxy group by the bilirubin UGT to form E2-3-glucuronide, this was in contrast with human liver microsomes which formed 3- and 17-glucuronides of this oestrogen. Studies utilizing microsomes from a Crigler-Najjar patient and inhibition of E2 glucuronidation with bilirubin indicated that the cloned expressed bilirubin UGT was the major human UGT isoform responsible for the formation of E2-3-glucuronide, which is the predominant E2 conjugate in human urine.
Mycobacterial Infections

The current issue of Seminars in Respiratory and Critical Care Medicine reviews the broad spectrum of diseases caused by mycobacterialinfections,including Mycobacteriumtuberculosis and nontuberculous mycobacteria (NTM). The ﬁ rst six articles provide in-depth reviews of tuberculosis, highlighting the changing epidemiology, advances in diagnosis, and treatment of both tuberculosis (TB) and latent tuberculosis infection (LTBI). The last seven articles focus on topics related to NTM infections, such as the human and environmental epidemiology and the diagnosis and treatment of NTM infections.
Silhouette classification by using manifold learning for automated threat detection

Video surveillance systems have become an essential tool to enhance security in both public and private places, especially to prevent potentially dangerous situations. However, these systems usually have a high number of nuisance alarms, when they are aimed at detecting automatically abandoned objects. It was found that people waiting (sitting or standing still) in airports, train stations and bus stops are the main cause of false alarms, as available video surveillance technologies are not focused on recognizing the abandoned objects. In this paper, we present a methodology to recognize abandoned objects. The goal is to determinate if the alarm is caused by an unattended baggage or a stationery person, as the former may pose potential security threats. The R transform, which is a geometric invariant feature descriptor and has low computational complexity, is applied to each of the four patches in which the silhouette of the object to be recognized is divided. Afterwards a covariance matrix representation is calculated from both the original high dimensional space and a low dimensional space obtained with Laplacian Egienmaps, being this matrix a point in a Riemannian Manifold. The proposed methodology is evaluated in a single person dataset and a baggage dataset (gathered from the web) and good performance was obtained.
Tannin Fingerprinting in Vegetable Tanned Leather by Solid State NMR Spectroscopy and Comparison with Leathers Tanned by Other Processes

Solid state 13C-NMR spectra of pure tannin powders from four different sources – mimosa, quebracho, chestnut and tara – are readily distinguishable from each other, both in pure commercial powder form, and in leather which they have been used to tan. Groups of signals indicative of the source, and type (condensed vs. hydrolyzable) of tannin used in the manufacture are well resolved in the spectra of the finished leathers. These fingerprints are compared with those arising from leathers tanned with other common tanning agents. Paramagnetic chromium (III) tanning causes widespread but selective disappearance of signals from the spectrum of leather collagen, including resonances from acidic aspartyl and glutamyl residues, likely bound to Cr (III) structures. Aluminium (III) and glutaraldehyde tanning both cause considerable leather collagen signal sharpening suggesting some increase in molecular structural ordering. The 27Al-NMR signal from the former material is consistent with an octahedral coordination by oxygen ligands. Solid state NMR thus provides easily recognisable reagent specific spectral fingerprints of the products of vegetable and some other common tanning processes. Because spectra are related to molecular properties, NMR is potentially a powerful tool in leather process enhancement and quality or provenance assurance.