Miracle-dz/UniFAR-FTUs huggingface dataset:
Actin Filament Cables in Drosophila Nurse Cells Are Composed of Modules That Slide Passively Past One Another during Dumping

At a late stage in Drosophila oogenesis, nurse cells rapidly expel their cytoplasm into the oocyte via intracellular bridges by a process called nurse cell dumping. Before dumping, numerous cables composed of actin filaments appear in the cytoplasm and extend inward from the plasma membrane toward the nucleus. This actin cage prevents the nucleus, which becomes highly lobed, from physically blocking the intracellular bridges during dumping. Each cable is composed of a linear series of modules composed of ∼25 cross-linked actin filaments. Adjacent modules overlap in the cable like the units of an extension ladder. During cable formation, individual modules are nucleated from the cell surface as microvilli, released, and then cross-linked to an adjacent forming module. The filaments in all the modules in a cable are unidirectionally polarized. During dumping as the volume of the cytoplasm decreases, the nucleus to plasma membrane distance decreases, compressing the actin cables that shorten as adjacent modules slide passively past one another just as the elements of an extension ladder slide past one another for storage. In Drosophila, the modular construction of actin cytoskeletons seems to be a generalized strategy. The behavior of modular actin cytoskeletons has implications for other actin-based cytoskeletal systems, e.g., those involved in Listeria movement, in cell spreading, and in retrograde flow in growth cones and fibroblasts.
Inappropriate Sinus Tachycardia Diagnosed and Treated as Depression Successfully Treated by Radiofrequency Catheter Ablation

We experienced a man in his 20s with inappropriate sinus tachycardia (IST) initially diagnosed and treated as depression who was steadily treated with radiofrequency catheter ablation (RFCA) using an EnSite™ system. The patient has remained well without any symptoms or medications, including antidepressants, for two years since the RFCA. To avoid missing IST and treating it as an emotional problem and/or mental illness such as depression, physicians - including cardiologists - should be aware of these conditions when examining patients with multiple and incapacitating complaints including palpitations and general fatigue and/or tachycardia, especially characterized by an elevated resting heart rate or a disproportionate increase in the heart rate with minimal exertion.
Temporalité de l'écriture et rôle du texte produit dans l'activité rédactionnelle

This article focuses on the way in which text production is conditioned, as it progresses, by the already-written text. This is a question that arises from both psychology, inasmuch as it studies the cognitive activity of writers, and linguistics, in that it studies textual features. The article thus examines first the epistemological and methodological problems that a pluridisciplinary approach to written production must take into account. Then it focuses on the temporal nature of writing (writing’s temporality) and foregrounds the different temporal strata in which the production of writing is inscribed. Finally, the article explores the dependence between already-produced text and text still to come, presenting the “ eye and pen ” tool that allows observation of ocular movements and thus highlights the way in which writers refer to already-produced text, which allows identification of writers’ differentiated behaviors.
Oral Contraceptives and Survival in Breast Cancer Patients Aged 20 to 54 Years

Recent oral contraceptive (OC) use is associated with modestly higher breast cancer incidence among younger women, but its impact on survival is unclear. This study examined the relationship between OC use before breast cancer diagnosis and survival. A population-based sample of 1,264 women aged 20 to 54 years with a first primary invasive breast cancer during 1990 to 1992 were followed up for 8 to 10 years. OC and covariate data were obtained by interviews conducted shortly after diagnosis and from medial records. All-cause mortality was ascertained through the National Death Index (n = 292 deaths). Age- and income-adjusted hazard ratios (HR) and 95% confidence intervals (95% CI) were estimated by Cox regression methods. All-cause mortality was not associated with ever use of OCs or duration of use. Compared with nonusers, mortality estimates were elevated among women who were using OCs at diagnosis or stopped use in the previous year (HR, 1.57; 95% CI, 0.95-2.61). The HR for use of high-dose estrogen pills within 5 years before diagnosis was double that of nonusers (HR, 2.39; 95% CI, 1.29-4.41) or, if the most recent pill included the progestin levonorgestrel, compared with nonusers (HR, 2.01; 95% CI, 1.03-3.91). Because subgroup estimates were based on small numbers of OC users, these results should be cautiously interpreted. Overall, most aspects of OC use did not seem to influence survival, although there is limited evidence that OC use just before diagnosis, particularly use of some pill types, may negatively impact survival in breast cancer patients aged 20 to 54 years. (Cancer Epidemiol Biomarkers Prev 2007;16(9):1822–7)
Alfabetización y educación: tres problemas para una teoría de la lecto-escritura

Resumen Un aspecto clave de la competencia escolar es la habilidad para interpretar y elaborar textos escritos. Se analiza este problema en tres partes: el problema de la escritura, concretamente la relación entre lo que queremos decir y lo que, de hecho, decimos; el problema de la lectura, concretamente diversas maneras en que se puede entender un texto; y el marco en el que se inserta el problema, concretamente la relación entre los géneros culturales y su importancia en el colegio y la sociedad.
A Seed-Selection Method to Increase Defect Coverage for LFSR-Reseeding-Based Test Compression

LFSR reseeding forms the basis for many test compression solutions. A seed can be computed for each test cube by solving a system of linear equations based on the feedback polynomial of the LFSR. Despite the availability of numerous LFSR-reseeding-based compression methods in the literature, relatively little is known about the effectiveness of these seeds for unmodeled defects. We use the recently proposed output deviation measure of the resulting patterns as a metric to select appropriate LFSR seeds. Experimental results are reported using test patterns for stuck-at faults derived from selected seeds. These patterns achieve higher coverage for stuck-open and transition faults than patterns obtained using other methods.
MUSIC TYPE GROUPERS (MTG): GENERIC MUSIC CLASSIFICATION ALGORITHMS

This paper outlines our submissions to different music classification tasks for the Music Information Retrieval Evaluation eXchange (MIREX) 2009. We detail here three different algorithms tested in mood and genre classification tasks, and in classical composer identification. These algorithms are based on Support Vector Machines, Disjoint Principal Components Models, and RCA-kNN. The last one utilizes Euclidean distances in a reduced space using Relevant Component Analysis and Kullback Leibler divergence on Mel Frequency Cepstrum Coefficients (MFCC). 1. FEATURE EXTRACTION The submissions are coded in C++ and python. For the feature extraction part, we use an internal library of the Music Technology Group called Essentia 1 . This library contains the features outlined below. We divide our features in two main categories. The “base” features which are state-of-the-art MIR features and the “high-level” fea tures. We aggregate frame-based descriptions using mean and derivatives until second order, variance and derivatives until second order, minimum, and maximum.
Clinicopathologic significance and prognostic value of chromosomal imbalances in diffuse large B-cell lymphomas.

PURPOSE To determine the clinicopathologic significance and prognostic value of chromosomal imbalances in diffuse large B-cell lymphomas (DLBCL). PATIENTS AND METHODS We have examined 64 tumors at diagnosis using comparative genomic hybridization and real-time quantitative polymerase chain reaction (PCR), single-stranded conformational polymorphism, and DNA sequencing for the analysis of several potential target genes. RESULTS The most recurrent alterations were gains of 18q (20%), Xq (15%), 2p, 7q, and 12p (14%), and losses of 6q and 17p (14%). Frequent high-level DNA amplifications were detected at 2p13-p16 and 18q21 loci. Real-time quantitative PCR detected REL and BCL11A gene amplifications in the nine patients with gains at 2p13-p16 and only in one additional patient with normal chromosome 2. Similarly, the BCL-2 gene was amplified in the 12 tumors with gains of 18q21 but in none of 39 patients with normal 18q profile. p53 gene inactivation was detected in nine of 58 (16%) tumors and was commonly associated with 17p losses. Tumors with 18q gains were significantly associated with a high number of chromosomal imbalances, primary nodal presentation, high serum lactate dehydrogenase levels, high International Prognostic Index, shorter cause-specific survival, and a high risk of relapse. Losses of 17p and p53 gene alterations were associated with an absence of complete response achievement. CONCLUSION These results suggest that DLBCLs have a characteristic pattern of genomic alterations; 18q gains or amplifications and 17p losses are associated with particular clinicopathological features and aggressive clinical behavior. Additional studies are needed to confirm these observations in larger series of patients.
Modeling, fabrication and performance measurements of a piezoelectric energy converter for power harvesting in autonomous microsystems

The present work deals with the energy conversion via the piezoelectric effect. A mechano-electrical energy converter based on piezoelectric thick films of lead zirconate titanate (PZT) deposited on a steel cantilever by a low-temperature process is presented. Modeling and measurement results on the performances of the piezoelectric converter are reported and their potential use in self-powered autonomous sensor devices is proposed
Resources Generated Through Extension Community Development Programs

A study was made in a small Missouri community which attempted to determine the value of the contributions which community members made to Extension Community Development activities. A total of 11 activities was identified by a group of community leaders as the most important things which the community had done during the past nine years. This group of leaders identified people they knew who had been actively involved in each activity. Each person was asked to specify how many hours of professional, skilled labor or "other" time he/she had contributed to the activity. This produced a total of 29,563 volunteer hours. An additional 21,292 hours were volunteered by other people and organizations within the community. It is estimated that the total value of resources generated by this small community was over one million dollars!
From symptom recognition to services: how South Asian Muslim immigrant families navigate autism

This study examined the experiences of three South Asian Muslim immigrant families who have a young child with autism. It describes the early period of their child’s disability as the families encountered four critical issues in their lives: a complex disability, the culturally diverse conceptualizations of the disability, family‐professional dynamics in cross‐cultural encounters and the search for appropriate services. Analyses were based on interviews with parents, supplemented by 17 months of participant‐observation in homes and community. Parents narrated their experiences beginning with symptom recognition through help seeking, diagnosis and subsequent service provision. Results suggest that for these families the challenging process of diagnosing and ameliorating autism is complicated by their unique positioning within and between diverse meaning systems. Challenges include American health and education professionals’ misunderstandings of their family organization and linguistic practices, and difficulties in cross‐cultural communication with professionals. Implications for professionals are discussed.
Dépendance-indépendance à l'égard du champ, activités opératoires et sénescence

Resume Afin d'etudier la variabilite interindividuelle et intra-individuelle des activites operatoires des sujets âges en fonction des styles cognitifs, 120 hommes de profession intellectuelle : 40 actifs jeunes et 80 retraites, sont examines a l'aide de 4 epreuves operatoires et du RFT. L'experience montre : 1) une forte dispersion intrasujet du niveau operatoire des senes-cents du fait notamment de certaines attitudes cognitives specifiques au vieil âge ; 2) La dependance-independance a l'egard du champ est associee : a) a la variabilite interindividuelle du niveau operatoire des sujets âges : l'independance du champ limite la baisse d'efficience dans les epreuves infralogiques ; b) a la variabilite intra-individuelle interepreuves : les senescents dependants sont plus disperses que les independants et, pour certaines paires d'epreuves, presentent des patrons de decalage differents. Mots clefs : senescence, activites operatoires, dependance-independance a l'egard du champ.
Apolipoprotein A-I and platelet factor 4 are biomarkers for infliximab response in rheumatoid arthritis

Objectives: The use of biologicals such as infliximab has dramatically improved the treatment of rheumatoid arthritis (RA). However, factors predictive of therapeutic response need to be identified. A proteomic study was performed prior to infliximab therapy to identify a panel of candidate protein biomarkers of RA predictive of treatment response. Methods: Plasma profiles of 60 patients with RA (28 non-responders (as defined by the American College of Rheumatology 20% improvement criteria (ACR20)) negative and 32 responders (ACR70 positive) to infliximab) were studied by surface enhanced laser desorption/ionisation time-of-flight mass spectrometry (SELDI-TOF MS) technology on two types of arrays, an anion exchange array (SAX2) and a nickel affinity array (IMAC3-Ni). Biomarker characterisation was carried out using classical biochemical methods (purification by ammonium sulfate precipitation or metal affinity chromatography) and identification by matrix assisted laser desorption/ionisation time-of-flight (MALDI-TOF) MS analysis. Results: Two distinct protein profiles were observed on both arrays and several proteins were differentially expressed in both patient populations. Five proteins at 3.86, 7.77, 7.97, 8.14 and 74.07 kDa were overexpressed in the non-responder group, whereas one at 28 kDa was increased in the responder population (sensitivity>56%, specificity>77.5%). Moreover, combination of several biomarkers improved the sensitivity and specificity of the detection of patient response to over 97%. The 28 kDa protein was characterised as apolipoprotein A-I and the 7.77 kDa biomarker was identified as platelet factor 4. Conclusions: Six plasma biomarkers are characterised, enabling the detection of patient response to infliximab with high sensitivity and specificity. Apolipoprotein A-1 was predictive of a good response to infliximab, whereas platelet factor 4 was associated with non-responders.
Influence of Nitrogen Fertilizer on the Growth, Yield and Quality of Grain Amaranth Varieties

Grain amaranth is an important leaf and seed vegetable crop in Nigeria. There is scanty information on its nutrient requirements for optimum yield and quality. Field experiments were conducted at Ladoke Akintola University of Technology Teaching and Research farm, Ogbomoso in the cropping seasons of 2004 and 2005 to determine the effect of nitrogen fertilizer on the growth, yield, quality and chemical composition of grain amaranth varieties. The investigated treatments were two varieties of grain amaranth; NH /593-1 and 84 NH /594 subjected into five levels of nitrogen fertilizer viz: 0, 15, 30, 45 and 60 kg N ha . These were assigned 84 1 randomly into three replicates and fitted into factorial experiment in a randomized complete block design. Data collected on the growth parameters, yield and quality attributes were analyzed using ANOVA. The plant height, number of leaves, dry matter yield of the leaves and stem of the grain amaranth increased significantly (P= 0.05) as the applied N rates was increased from 0 kg ha up to 60 kg ha of N. The grain yield and quality of the 11 grain amaranth varieties were increased from 0 up to 45 kg N ha and declined thereafter. The combined 1 nitrogen and varietal effects were significant for the grain yield in both years. The highest grain yield was recorded for NH /593-1 while NH /594 gave the least values with and without N application. Although, all the 84 84 plant parts are very rich in protein, fat, carbohydrate and other nutrient elements, the leaves recorded the highest contents followed by the grain and the stem. Therefore, the optimum N rate for the maximum yield and quality of grain amaranth is 45 kg N ha and NH /593-1 is adjudged as the best variety for the southwestern 1 84 Nigeria.
Social Exclusion of Pakistani and Bangladeshi Women

This paper explores some of the processes that influence access to higher education and employment for Pakistani and Bangladeshi women in Britain. We ask what changes we can expect amongst younger Pakistani and Bangladeshi women who have grown up in the UK? How do we expect educational qualifications and family formation to influence labour market participation amongst these women? What barriers do these women face in obtaining qualifications and paid employment? To what extent are these barriers imposed by the family and community and to what extent are they imposed by the local labour market? We find evidence of change across generations. By contrast with their mothers' generation, younger women who had been educated in the UK saw paid work as a means to independence and self- esteem. Women with higher level qualifications often showed considerable determination in managing to combine paid work and child-care. Whilst most women subscribed strongly to the centrality of the family, it is clear that the majority will follow very different routes through the life-course from their mothers. However, even with higher level qualifications, women are facing considerable barriers to employment. If the expected increase in economic activity amongst Pakistani and Bangladeshi women is not to lead to even higher unemployment, there is a pressing need to ensure that potential employers do not hold negative and out-dated stereotypes of traditional Muslim women.
A 3D-Based Pose Invariant Face Recognition at a Distance Framework

Face recognition in the wild can be defined as recognizing individuals unabated by pose, illumination, expression, and uncertainties from the image acquisition. In this paper, we propose a framework recognizing human faces under such uncertainties by focusing on the pose problem while considering the other factors together. The proposed work introduces an automatic front-end stereo-based system, which starts with image acquisition and ends by face recognition. Once an individual is detected by one of the stereo cameras, its facial features are identified using a facial features extraction model. These features are used to steer the second camera to see the same subject. Then, a stereo pair is captured and 3D face is reconstructed. The proposed stereo matching approach carefully handles illumination variance, occlusion, and disparity discontinuity. The reconstructed 3D shape is used to synthesize virtual 2D views in novel poses. All these steps are done off-line in an Enrollment stage. To recognize a face from a 2D image, which is captured under unknown environmental conditions, another fast on-line stage starts by facial features detection. Then, a facial signature is extracted from patches around these facial features. Finally, this probe image is matched against the closest synthesized images. Experiments are conducted on different public databases from where we investigate the effect of each component of the proposed framework on the recognition performance. The results confirm that without training and with automatic features extraction, our proposed face recognition at a distance approach outperforms most of the state-of-the-art approaches.
Science and Government in Victorian England: Lighthouse Illumination and the Board of Trade, 1866-1886

T HE GROWTH of government participation in the conduct of British science has long interested historians of science and technology who recognize the significance of social factors in the application of scientific ideas. Within recent years, however, the subject has also become attractive to students of social, economic, and administrative history. In part this new interest has arisen from current preoccupations with the expanding demands made by science on the country's budget and with the necessity to design appropriate policies for the administration of fundamental and applied research. Just as the postwar years of welfare-state-making found historians looking for the historical roots of the social services, so we have now begun to probe beneath "current history" for lessons and experience bequeathed by the past.2
Distribution of Aerobic Bacteria Which Contain Bacteriochlorophyll a

Sixteen strains of aerobic bacteria which contain bacteriochlorophyll a were isolated from the samples collected in aerobic marine environments: thalli of Enteromorpha linza, Porphyra sp. , Sargussum horneri; beach sand; and the surface seawater from Aburatsubo Inlet. When they occurred, their proportions among the aerobic heterotrophic populations ranged from 0.9 to 1.1% in the seaweed samples and from 1.2 to 6.3% in the beach sand samples and were 0.9% in the seawater sample. The results suggested that the aerobic photopigmented bacteria widely inhabit aerobic marine environments.