Miracle-dz/UniFAR-FTUs huggingface dataset:
Special Events: Creating and Sustaining a New World for Celebration,

Foreword ix Preface xi Acknowledgments xxiii PART ONE Sustainable Event Leadership CHAPTER 1: Welcome to a Changing World 3 CHAPTER 2: Models of Sustainable Event Leadership 43 PART TWO Event Orchestration CHAPTER 3: Composing the Event Plan 77 CHAPTER 4: Human Resources and Time Management 115 CHAPTER 5: Sustainable Financial Leadership 139 PART THREE Delivering on the Promise CHAPTER 6: Vendor Partners, Contracts, and On-Site Production 171 CHAPTER 7: Marketing and Integrated Communications Technology 217 CHAPTER 8: Risk Management: Health and Safety, Legal, and Ethical Safeguards 259 PART FOUR Traditions and Trends CHAPTER 9: Virtual Events 295 CHAPTER 10: Career Growth and Sustainable Development 315 PART FIVE Best Practices and Real World Event Experiences CHAPTER 11: Global, National, Regional, and Local Best Practices in Event Leadership 351 CHAPTER 12: Twenty-Five Real-World Event Management Experiences and Mini-Case Studies 365 Appendix 1 Bibliographic References 378 Appendixes 2 19 and accompanying Image Gallery are available online at www.wiley. com/college/goldblatt Glossary 386 Index 393
A Machine-Compiled Database of Genome-Wide Association Studies

Tens of thousands of genotype/phenotype associations have been discovered by experimental studies, yet not all of them are available to scientists in a useful, easy to access format. Here, we describe GwasDB, a machine reading system for automatically extracting these associations from the scientific literature in the form of a structured database. Our system reveals that existing manually-curated repositories are highly incomplete, and produces > 3, 000 previously undocumented associations, which represents about 30% of the size of the largest existing repository of open-access papers. Our results highlight both the importance and the feasibility of using machines to help human curators keep track of important scientific findings obtained using public research funding.
Lamellar macular holes: monitoring and management strategies

Abstract Lamellar macular holes are a vitreoretinal condition characterized by abnormalities in foveal contour with splitting of the neuroepithelium and often an intact photoreceptor layer. Recent developments in high-resolution imaging have increased our ability to study the details of the vitreoretinal interface and to distinguish between different forms of lamellar holes. A new classification is needed to help clinicians in the management of lamellar macular holes. Some clinicians prefer to observe these clinical entities, especially when visual acuity is maintained or alterations of the photoreceptor layer are present. Nevertheless, lamellar holes may sometimes progress, and visual acuity can deteriorate. On the other hand, surgical treatment may lead to positive anatomical and functional outcomes, but not without risks. This review provides a critical overview of the available data on lamellar macular holes, focusing on diagnosis and managing options.
Distinct prognostic values of alcohol dehydrogenase mrna expression in pancreatic adenocarcinoma

Background: Alcohol dehydrogenase (ADH) isoenzymes have been reported as a potential diagnostic marker for pancreatic cancer, but their prognostic value in pancreatic cancer remains unclear. The aim of this investigation was to identify the prognostic value of ADH genes in human patients with pancreatic adenocarcinoma (PAAD). Materials and methods: An RNA sequencing dataset and corresponding survival profiles of PAAD were obtained from The Cancer Genome Atlas. Survival analysis and gene set enrichment analysis were used to investigate the prediction value and potential mechanism of ADH genes in PAAD prognosis. Results: Survival analysis of ADH genes suggests that a high expression of ADH1A (adjusted P = 0.037, adjusted hazard ratio [HR] = 0.627, 95% CI = 0.404–0.972) and ADH6 (adjusted P = 0.018, adjusted HR = 0.588, 95% CI = 0.378–0.914) were associated with a significantly decreased risk of death, while a high expression of ADH5 was associated with a significantly increased risk of death (adjusted P = 0.043, adjusted HR = 1.564, 95% CI = 1.013–2.414). Joint effects analysis of three ADH gene prognostic markers suggests that the prognosis difference for any marker combination was more significant than that for any individual marker. The potential mechanism of ADH1A and ADH6 in PAAD prognosis was that a high expression of ADH1A and ADH6 was involved in the P450 pathway and biological processes, while high ADH5 expression was involved in transforming growth factor β regulation-related pathways and biological processes, Wnt, the cell cycle, ErbB, and mitogen-activated protein kinase signaling pathways. Conclusion: Our data suggest that ADH1A , ADH5 , and ADH6 expression may be potential prognostic markers of PAAD and in combination have a strong interaction and better predictive value for PAAD prognosis.
Long Non-Coding RNA Expression Profiles in Hereditary Haemorrhagic Telangiectasia

Hereditary Haemorrhagic Telangiectasia (HHT) is an autosomal dominantly inherited vascular disease characterized by the presence of mucocutaneous telangiectasia and arteriovenous malformations in visceral organs. HHT is predominantly caused by mutations in ENG and ACVRL1, which both belong to the TGF-β signalling pathway. The exact mechanism of how haploinsufficiency of ENG and ACVRL1 leads to HHT manifestations remains to be identified. As long non-coding RNAs (lncRNAs) are increasingly recognized as key regulators of gene expression and constitute a sizable fraction of the human transcriptome, we wanted to assess whether lncRNAs play a role in the molecular pathogenesis of HHT manifestations. By microarray technology, we profiled lncRNA transcripts from HHT nasal telangiectasial and non-telangiectasial tissue using a paired design. The microarray probes were annotated using the GENCODE v.16 dataset, identifying 4,810 probes mapping to 2,811 lncRNAs. Comparing HHT telangiectasial tissue with HHT non-telangiectasial tissue, we identified 42 lncRNAs that are differentially expressed (q<0.001). Using GREAT, a tool that assumes cis-regulation, we showed that differently expressed lncRNAs are enriched for genomic loci involved in key pathways concerning HHT. Our study identified lncRNAs that are aberrantly expressed in HHT telangiectasia and indicates that lncRNAs may contribute to regulate protein-coding loci in HHT. These results suggest that the lncRNA component of the transcriptome deserves more attention in HHT. A deeper understanding of lncRNAs and their role in telangiectasia formation possesses potential for discovering therapeutic targets in HHT.
Supplement for : A graph-based evidence synthesis approach to detecting outbreak clusters : an application to dog rabies

Choosing the cutoffs based on preexisting information about the pathogen of interest 2 Notations . 2 Distribution of the distance between two cases accounting for underreporting . 3 Special case 1: φ is the pdf of a Gamma distribution (typical for serial interval distribution) . 3 Special case 2: φ is the pmf of a negative binomial distribution (typical for transmission divergence distribution) . 3 Special case 3: φ is the pdf of a Rayleigh distribution (typical for spatial kernel distribution) . 4
DYNAMICS AND STIFFNESS ANALYSIS OF A HOMOPOLAR MAGNETIC BEARING

Decreasing eddy current is very important for the realization of stability control of HoMB system. In order to improve the dynamic performance precision of HoMB in the design stage, the dynamics and stiffness analysis of a homopolar magnetic bearing (HoMB) has been studied in this paper. Because the polarities of the magnetic poles were not changed during the rotation of rotor, the effect of eddy-currents was often ignored in the previous researches. However, when the frequencies of vibration caused by external disturbance and control currents are very high, eddy-current effects have significant influence on the performance of HoMB. In order to predict the HoMB performance, guide the HoMB design and control of the HoMB system in high frequency, a dynamics model was built on the equivalent circuit method. Parameters of dynamic Modeling are frequency-dependent. The effect of eddy-currents on the current stiffness was studied. The analysis results show that the eddy current effect on HoMB can be reduced by increasing the air gap, decreasing the laminations thickness and decreasing the laminations conductivity.
Sexually dimorphic gene expression and transcriptome evolution provides mixed evidence for a fast-Z effect in Heliconius

Sex chromosomes have different evolutionary properties as compared to the autosomes due to their hemizygous nature. In particular, recessive mutations are more readily exposed to selection, which can lead to faster rates of molecular evolution. Here, we report patterns of gene expression and molecular evolution in the sex chromosomes of a group of tropical butterflies. We first improved the completeness of the Heliconius melpomene reference annotation, a neotropical butterfly with a ZW sex determination system. Then we sequenced RNA from male and female whole abdomens and female ovary and gut tissue to identify sex and tissue specific gene expression profiles in H. melpomene. Using these expression profiles we compare sequence divergence and polymorphism, the strength of positive and negative selection and rates of adaptive evolution for Z and autosomal genes between two species of Heliconius butterflies, H. melpomene and H. erato. We show that the rate of adaptive substitutions is higher for Z as compared to autosomal genes, but contrary to expectation it is also higher for male as compared to female biased genes. There is therefore mixed evidence that hemizygosity influences the rate of adaptive substitutions. Additionally, we find no significant increase in the rate of adaptive evolution or purifying selection on genes expressed in ovary tissue, a heterogametic specific tissue. Together our results provide limited support for fast-Z evolution. This contributes to a growing body of literature from other ZW systems that also provide mixed evidence for a fast-Z effect.
University of Southern Denmark Prevalence of coronary artery calcification in a non-specific chest pain population in emergency and cardiology departments compared with the background population A prospective cohort study in Southern Denmark with 12-month follow-up of cardiac endpoints

Objectives To examine and compare the prevalence of coronary artery calcification (CAC) and the frequency of cardiac events in a background population and a cohort of patients with non-specific chest pain (NSCP) who present to an emergency or cardiology department and are discharged without an obvious reason for their symptom. Design A double-blinded, prospective, observational cohort study that measures both CT-determined CAC scores and cardiac events after 1 year of follow-up. setting Emergency and cardiology departments in the Region of Southern Denmark. subjects In total, 229 patients with NSCP were compared with 722 patients from a background comparator
Spatial analysis of housing markets with land rent theory of political economy: the cases of London, Seoul and Los Angeles

This study adopts Marxian land rent theory as a framework to understand the structure of house prices with explicit attention to labour reproduction in an urban context. It attempts to correct the misunderstandings in Marxian land rent theory and develop it for an urban context. The four categories of land rent of differential rent, differential rent 2, absolute rent, and monopoly rent are critically re-examined. Subsequently, the combination of absolute rent and differential rent is suggested as a general structure for land rents in an urban context. The dynamic mechanism of changes in land rents is explained with the concepts of emulation, differentiation and shift between groups of houses based on the structure of land rents. The process of the formation of housing submarkets has been examined for a practical preparation for empirical analysis and a theoretical basis for the subdivision of the housing market. Spatial submarkets are identified by focusing on the interactive relationship between residential spheres (a unit consisting of a centre of employment and the surrounding residential area). Sectoral submarkets are defined based on social and environmental features as well as the structural features of dwellings. For empirical analysis, three metropolitan cities were chosen: London as monocentric, Seoul as tri-centric and Los Angeles as polycentric. Empirical analysis has used commuting patterns and the contours of house prices as the criteria to identify spatial submarkets with the help of network analysis and GIS. Simple OLS regression analysis of house prices on the accessibility to centre was conducted in each identified submarket. The results were used to explore the structure of and the dynamic changes in land rents. A consistent structure of land rents was observed in each housing submarket across all three cities. The implication on the condition of labour reproduction was drawn out by interpreting the changes in land rents over a period of 10 years in each city. The analysis of London revealed a monocentric housing market structure and the suitability of commuting time over physical distance as an accessibility variable. In Seoul‟s case, the transition from tri-centric to monocentric housing market was observed and a comparative approach with rent and price data enriched the interpretation of the changes in the structure of the housing market. The impact of social and environmental features of the neighbourhood, such as class, ethnic concentration and negative externality, on house prices was highlighted in the analysis of Los Angeles.
Forecasting incidence of infectious diarrhea using random forest in Jiangsu rovince, China

Background: Infectious diarrhea can lead to considerable disease burden around the world. Thus, the accurate prediction of infectious diarrhea epidemic is crucial for public health authorities. This study aimed to develop an optimal random forest (RF) model considering meteorological factors to predict morbidity of infectious diarrhea in Jiangsu Province, China. Methods: A RF model was constructed and compared with the classical autoregressive integrated moving average (ARIMA)/X models. Morbidity and meteorological data from 2012−2016 were used for model construction and the rest data in 2017 were used for testing. Results: The RF model considered atmosphere pressure, precipitation, relative humidity and their lagged terms, 1-4 weeks’ lag morbidity and the time variable as predictors. Meanwhile, a univariate model ARIMA(1,0,1)(1,0,0) 52 (AIC=−575.92, BIC=−558.14) and a multivariable model ARIMAX(1,0,1)(1,0,0) 52 with 0-1 week’s lag precipitation (AIC=−578.58, BIC=−578.13) were developed as benchmark models . The RF model outperformed the ARIMA/X models with a mean absolute percentage error (MAPE) of approximately 20% . The performance of the ARIMAX model was similar to that of the ARIMA model with MAPE approximately as high as 30%. Conclusions: The RF model well fitted the dynamic of the infectious diarrhea epidemic and achieved ideal prediction accuracy. It comprehensively combined meteorological factors and their hysteresis effects. It also integrated the autocorrelation and seasonality of morbidity. The RF model could be used to predict the epidemic level, and has good potential of practical application.
Historical resource use and ecological change in semi-natural woodland : western oakwoods in Argyll, Scotland

This thesis investigates the ecological history of western oakwoods in the Loch Awe area, Argyll, Scotland. By combining historical evidence for human use of woodland resources with palaeoecological evidence for past ecological change the influence of man on the current condition of biologically important semi-natural woods is assessed. A chronology of human activities relevant to the woodland ecology of the study area is assembled from estate papers and other documentary sources. Vegetation change during the last c. 1000 years is elucidated by pollen analysis of radioisotope dated sediments from small hollows located within three areas of western oakwood believed to be ancient. The results are related to current condition and the hypothesis that the species composition of the woods exhibited temporal stability in the recent past is tested. Mechanisms of change culminating in the modem species compositions of the woods are suggested by synthesizing independent findings from historical and palaeoecological approaches. The documentary record indicates management in the 18 and 19 centuries to supply oak bark and coppice wood for commercial purposes. In the 20 century woodland use has been relatively minor except as a grazing resource. In the period before 1700 AD the woods were used for wood for local domestic needs and to shelter livestock. The palaeoecological record indicates a lack of stability in species composition during the last millennium. Relatively diverse woods still containing natural features such as old-growth were transformed in the medieval period into disturbed open stands depleted in natural features. Declining productivity was locally alleviated by the introduction of new modes of exploitation around or prior to 1700 AD. The current condition of the woods, rather than being the direct result of an economic design, is the consequence of post-disturbance biotic processes following the abandonment of management in the late 19 century. The findings are related to the conservation of the wider western oakwood resource.
A combined continuum and discrete network reactive transport model for the simulation of karst development

A seal for the T-joint between upper and lower engine crankcase members and a crankshaft seal member has a longitudinal portion received between and engaging the upper and lower crankcase members, and a generally triangular tip formed by a shorter side and a longer side with the shorter side facing toward the crankshaft seal member as the crankshaft seal member is installed. The tip deforms as the crankshaft member is installed, and thereby seals the T-joint.
Ionization dynamics of dense matter generated by intense ultrashort X‐ray pulses

We investigate a pump‐probe X‐ray Thomson scattering (XRTS) experiment that might be carried out at a free electron laser facility to study warm‐to‐hot states of dense matter. Ultrashort and intense X‐ray pulses with different energies (1,560–1,830 eV) heat a 1 µm thick Al target isochorically and create homogeneous and uncompressed warm‐to‐hot states of dense matter. A second pulse with variable delay probes this heated state via XRTS. The X‐ray laser–target interaction is modelled within radiation‐hydrodynamic simulations applying the HELIOS‐CR code. The HELIOS‐CR results qualitatively agree with Monte‐Carlo simulations, where the laser pulse absorption is simulated based on a uniform random sequence of events. The electron feature in the simultaneously observed X‐ray scattering spectrum is a function of the degree of ionization and the target temperature. Therefore, the temporal evolution of the plasmon peak measures the ionization dynamics on ultra‐short time scales. The XRTS spectrum is calculated based on the Chihara formula utilizing the Born‐Mermin approximation for the free electron dynamic structure factor. The proposed experiment will reveal important details of the ionization dynamics on ultra‐short time scales as well as of the relaxation on ps time scales.
Influence of riparian buffer management strategies on soil properties

OF DISSERTATION INFLUENCE OF RIPARIAN BUFFER MANAGEMENT STRATEGIES ON SOIL PROPERTIES The Kentucky Division of Water indicates that agriculture is responsible for 55% of the Commonwealth’s assessed streams not supporting their designated uses. Riparian buffers reduce nonpoint source pollution in agroecosystems by storing and cycling nutrients, stabilizing streambanks, increasing infiltration, and storing water. Specific information regarding riparian buffer management is needed for land managers to maximize buffer effectiveness at reducing agricultural contaminants impairing water quality. Baseline soil properties (texture, pH, C and nutrients) of the riparian buffer surrounding a tributary of Cane Run Creek in Fayette County, KY were characterized prior to imposing three mowing regimes (intense, moderate, and no mow treatments) and one native grass regime. Measurements were made along parallel transects located 2-m and 8-m distances from the stream. Root biomass, aggregate distribution, and saturated hydraulic conductivity were measured along the 2-m transect in two consecutive years following treatment establishment. The 2-m transect soils had the highest C, pH, Ca, Zn, and sand content. The 8-m transect had the highest P, K, Mg, and clay content. Semivariogram analysis of C content indicated slight to moderate spatial dependency along the 2m transect and moderate to strong spatial dependency along the 8m transect. Root biomass increased with decreased mowing frequency at the surface depth after one year; the native grass treatment had significantly less root biomass in both years compared to mowing treatments. There was no significant treatment effect on aggregate size distribution at the surface depth in either year. Mean weight diameter and large macroaggregates decreased from 2011 to 2012. Vegetation treatment had no statistically significant effect on water stable aggregates or saturated hydraulic conductivity. Experimental semivariograms provided evidence of spatial structure at multiple scales in root biomass, aggregates, and soil C. Spatial variability occurred over a shorter lag distance in 2012 than 2011, suggesting an effect of imposed treatments slowly developing over time. This study provides important insights on riparian buffer soil properties, soil sampling strategies to detect spatial variability in riparian buffers, and length of time needed to assess effects of vegetation management regimes on riparian root biomass, soil aggregates, and hydraulic conductivity.
Understanding uncertainties in the response of ENSO to greenhouse warming

The response of ENSO to increases in greenhouse gases is found to be markedly different in climate change simulations using two different versions of the Hadley Centre Coupled Models (HadCM2 and HadCM3). Using HadCM2, Collins [2000] found an increase in the amplitude, an increase in the frequency, and a shift in the phase of ENSO at 4×CO2. In HadCM3 it is shown that there are no significant changes in ENSO statistics at 4×CO2. Differences in the two models ENSO response are traced to differences in the response of the mean meridional gradients of temperature either side of the equator. These differences in the mean pattern of climate change are brought about by subtle changes in the physical parametrisation schemes, rather than the main differences between HadCM2 and HadCM3 which are enhanced horizontal ocean resolution and the removal of flux adjustments. Thus the response of ENSO variability to increasing greenhouse gases can depend in an unexpected and quite non‐linear way to subtle changes in the models representation of sub grid‐scale processes.