Miracle-dz/UniFAR-FTUs huggingface dataset:
Green Synthesis of Zinc Oxide Nanocrystals Utilizing Origanum majorana Leaf Extract and Their Synergistic Patterns with Colistin against Multidrug-Resistant Bacterial Strains

There is a crucial necessity for the formulation of efficient antimicrobial agents owing to the increasing prevalence of hospital-acquired bacterial infections triggered by multidrug-resistant microbes that result in significant deaths and illnesses around the world. Hence, the current investigation examined the antibacterial proficiency of zinc oxide nanoparticles formulated utilizing the green route against bacterial strains that were resistant to multiple drugs. In addition, the synergistic antibacterial action of ZnO nanoparticles (ZnO NPs) combined with colistin was investigated against the tested microbial strains to determine the efficiency of the bioinspired ZnO nanoparticles in boosting the antibacterial proficiency of colistin antibiotic. Incidentally, the bioinspired ZnO nanoparticles were synthesized using water extract of Origanum majorana leaves and these nanomaterials were physicochemically characterized using different analytical techniques. The bioactivity of the synthesized nanomaterials against multidrug-resistant bacterial strains was appraised using the agar diffusion method. The biogenic ZnO NPs at a concentration of 100 μg/disk revealed a compelling antimicrobial efficacy against the tested strains, expressing the maximum antimicrobial action against Escherichia coli strain with clear zone diameter of 38.16 ± 0.18 mm. The remarkable antibacterial proficiency might be accredited to the tiny particle size of the bioformulated ZnO NPs of 12.467 ± 1.36 nm. The net charge of ZnO nanomaterials was −14.8 mV while XRD analysis confirmed their hexagonal wurtzite structure. Furthermore, the bioformulated ZnO NPs showed a promising synergistic potency with colistin demonstrating respective synergism proportions of 91.05, 79.07, 75.04, 75.25, 56.28 and 10.60% against E. coli, Klebsiella pneumoniae, Acinetobacter baumannii, Salmonella typhimurium, Enterobacter cloacae, and Pseudomonas aeruginosa, respectively. In conclusion, the water extract of O. majorana leaves mediated green formulation of zinc oxide nanoparticles with unique physicochemical characteristics and effective antibacterial proficiency against the examined drug-resistant bacterial strains. These nanomaterials could be used in the synthesis of effective antibacterial coatings to control hospital acquired infections caused by multidrug-resistant bacterial pathogens.
What Can We Learn about GRB from the Variability Timescale Related Correlations?

Recently, two empirical correlations related to the minimum variability timescale (MTS) of the light curves are discovered in gamma-ray bursts (GRBs). One is the anti-correlation between MTS and Lorentz factor Γ, and the other is the anti-correlation between the MTS and gamma-ray luminosity Lγ. Both of the two correlations might be used to explore the activity of the central engine of GRBs. In this paper, we try to understand these empirical correlations by combining two popular black hole central engine models (namely, the Blandford & Znajek mechanism (BZ) and the neutrino-dominated accretion flow (NDAF)). By taking the MTS as the timescale of viscous instability of the NDAF, we find that these correlations favor the scenario in which the jet is driven by the BZ mechanism.
Foundations of Rational Quantum Field Theory, I

We study the connection between Rational Conformal Field Theory (RCFT), $N=2$ massive supersymmetric field theory, and solvable Interaction Round the Face (IRF) lattice models. Specifically, one identifies the fusion rings with the chiral rings. The theories so obtained are conjectured, and largely shown, to be integrable. A variety of examples and the structure of the metric in moduli space are given. The kink scattering theory is given by the Boltzmann weights of an IRF model, which is built entirely in terms of the conformal data of the original RCFT. This procedure produces all solvable IRF models in terms of projection operators of the RCFT. The soliton structure and their scattering amplitudes are described. A host of new rational conformal field theories is constructed generalizing most, if not all, of the known ones.
Eigenvalues of matrices

Preface to the classics edition Preface Preface to the English edition Notation List of errata 1. Supplements from linear algebra 2. Elements of spectral theory 3. Why compute eigenvalues? 4. Error analysis 5. Foundations of methods for computing eigenvalues 6. Numerical methods for large matrices 7. Chebyshev's iterative methods 8. Polymorphic information processing with matrices Appendix A. Solution to exercises Appendix B. References for exercises Appendix C. References Index.
Buonomano against Bell: Nonergodicity or nonlocality?

The aim of this note is to attract attention of the quantum foundational community to the fact that in Bell's arguments one can not distinguish two hypotheses: a) quantum mechanics is {\it nonlocal}, b) quantum mechanics is {\it nonergodic. } Therefore experimental violations of Bell's inequality can be as well interpreted as supporting the hypothesis that stochastic processes induced by quantum measurements are nonergodic. The latter hypothesis was discussed actively by Buonomano since 1980th. However, in contrast to Bell's hypothesis on nonlocality it did not attract so much attention. The only experiment testing the hypothesis on nonergodicity was performed in neutron interferometry (by Summhammer, in 1989). This experiment can be considered as rejecting this hypothesis. However, it cannot be considered as a decisive experiment. New experiments are badly needed. We point out that a nonergodic model can be realistic, i.e., the distribution of hidden (local! ) variables is well defined. We also discuss coupling of violation of the Bell inequality with violation of the condition of weak mixing for ergodic dynamical systems.
Impact of photometric redshifts on the galaxy power spectrum and BAO scale in the LSST survey

Context. The Large Synoptic Survey Telescope (LSST) survey will image billions of galaxies every few nights for ten years, and as such, should be a major contributor to precision cosmology in the 2020s. High precision photometric data will be available in six bands, from near-infrared to near-ultraviolet. The computation of precise, unbiased, photometric redshifts up to at least z = 2 is one of the main LSST challenges and its performance will have major impact on all extragalactic LSST sciences. Aims. We evaluate the efficiency of our photometric redshift reconstruction on mock galaxy catalogues up to z = 2.45 and estimate the impact of realistic photometric redshift (photo-z) reconstruction on the large-scale structures (LSS) power spectrum and the baryonic acoustic oscillation (BAO) scale determination for a LSST-like photometric survey. We study the effectiveness of the BAO scale as a cosmological probe in the LSST survey. Methods. We have performed a detailed modelling of the photo-z distribution as a function of galaxy type, redshift and absolute magnitude using our photo-z reconstruction code with a quality selection cut based on a boosted decision tree (BDT). We have simulated a catalogue of galaxies in the redshift range [0.2−2.45] using the Planck 2015 ΛCDM cosmological parameters over 10 000 square-degrees, in the six bands, assuming LSST photometric precision for a ten-year survey. The mock galaxy catalogues were produced with several redshift error models. The LSS power spectrum was then computed in several redshift ranges and for each error model. Finally we extracted the BAO scale and its uncertainty using only the linear part of the LSS spectrum. Results. We have computed the fractional error on the recovered power spectrum which is dominated by the shot noise at high redshift (z ≳ 1), for scales k ≳ 0.1, due to the photo-z damping. The BAO scale can be recovered with a percent or better accuracy level from z = 0.5 to z = 1.5 using realistic photo-z reconstruction. Conclusions. Reaching the LSST requirements for photo-z reconstruction is crucial to exploit the LSST potential in cosmology, in particular to measure the LSS power spectrum and its evolution with redshift. Although the BAO scale is not the most powerful cosmological probe in LSST, it can be used to check the consistency of the LSS measurement. Moreover we show that the impact of photo-z smearing on the recovered isotropic BAO scale in LSST should stay limited up to z ≈ 1.5, so as long as the galaxy number density balances the photo-z smoothing.
Patterns of Posidonia oceanica (L.) Delile tannin cells and leaf characteristics according to environmental conditions

There is little research on the distribution and evolution of tannin cells, specialized in the sequestration of phenolic compounds, in the leaves of P. oceanica, depending on the developmental stage and environmental conditions. This work aims to evaluate the density of tannin cells along the vertical axis of leaves (basal, middle, and apical regions) at four sites corresponding to an anthropogenic gradient estimated from the ecological status of P. oceanica meadows: Moderate (El Djamila), Good (Bou Ismaïl) and very good (Kouali and Aïn Tagouraït). Leaf thickness and width were measured in each region to express the density of tannin cells per mm². Data analysis shows that the density of tannin cells decreases with increasing leaf age and that the highest densities are recorded in the apical regions, especially when the leaf apex is entire. The density of leaf tannin cells is significantly correlated (R = -0.977, p = 0.022) with the Ecological Quality Ratio (EQR) corresponding to the ecological status of P. oceanica meadows and reflecting the impact of environmental pressures. This sensitivity to environmental conditions opens interesting prospects for using tannin cell density as a descriptor (environmental biomarker) in coastal monitoring programs based on P. oceanica meadows.
Rayleigh and acoustic gravity waves detection on magnetograms during the Japanese Tsunami, 2011

The continuous geomagnetic field survey holds an important potential in future prevention of tsunami damages, and also, it could be used in tsunami forecast. In this work, we were able to detected for the first time Rayleigh and ionospheric acoustic gravity wave propagation in the Z-component of the geomagnetic field due to the Japanese tsunami, 2011 prior to the tsunami arrival. The geomagnetic measurements were obtained in the epicentral near and far-field. Also, these waves were detected within minutes to few hours of the tsunami arrival. For these reasons, these results are very encouraging, and confirmed that the geomagnetic field monitoring could play an important role in the tsunami warning systems, and also, it could provide additional information in the induced ionospheric wave propagation models due to tsunamis.
Some asymptotic theory for functional regression with stationary regressor

: The general asymptotic distribution theory for the functional re- gression model in Ruymgaart et al. [Some asymptotic theory for functional regression and classiﬁcation (2009) Texas Tech University] simpliﬁes consider- ably if an extra assumption on the random regressor is made. In the special case where the regressor is a stochastic process on the unit interval, Johannes [Priv- ileged communication (2008)] assumes the regressor to be stationary, in which case the eigenfunctions of their covariance operator turn out to be known, so that only the eigenvalues are to be estimated. In the present paper we will also assume the eigenvectors to be known, but within an abstract set- ting. The simpliﬁcation mentioned above is due to the circumstance that the covariance operator of the regressor commutes with its estimator as it can be constructed under the current conditions. Moreover, it is now possible to test linear hypotheses for the regression parameter that correspond to linear subspaces spanned by a ﬁnite number of the known eigenvectors.
10.D. Workshop: Injury Severity Classification and burden of disability measurement

Abstract Globally, injuries cause over 4.3 million deaths per year with incalculable costs for the health, legal, and social systems. Burden of disease analyses are being conducted across the world in order to map the health status of injured population, run comparisons and enable prioritization of preventive and interventional measures. Metrics of injury burden are therefore important indicators of population health that are increasingly being incorporated into national and international health information systems. To prevent injuries and their disabling health consequences, and to effectively reduce injury burden, it is essential to provide policy makers and health system planners with detailed measurements and assessments that allow them to focus resources where they are most needed and areas where more targeted policy attention might be required. However, efforts to fully understand the health outcomes of trauma patients remain inconsistent and insufficient, specifically for certain injury populations and health outcome domains. A wide variety of measures are available to track outcomes after injury in various health domains. Reaching consensus is an important step in benchmarking of outcomes across institutions and injury types to improve quality and advance the field of injury care. Modern, validated measures that are feasible and usable in both research and clinical contexts are needed to facilitate the improvement of quality and comparability of research. The workshop aims to discuss trends and variation of injury burden, which is critical to health system planning. The high human and societal costs as well as inequalities of injury mortality and burden will be highlighted based on comparisons with long-term trends. The workshop will discuss the latest developments in injury severity classification and disability measurement. The most efficient measures to calculate the valid burden of injuries will be presented and comparative measurements across EU countries will be promoted. Limitations of injury classifications and factors introducing uncertainty and potential bias in estimation of disability, will be identified. The workshop will contribute to the identification of evidence-informed tools and measurements of injury burden. Key messages • Some injury outcomes are responsible for huge individual and societal burden but are still difficult to measure. • Multiple measures are developed to assess severity and outcomes: e.g. AIS/ ISS/New ISS/ ICD-10. Efficient prevention and quality care requires validated and easy to use measures.
BmAbl1 Regulates Silk Protein Synthesis via Glutathione Metabolism in Bombyx mori

Simple Summary Silk yield is the primary economic character in sericulture. During the past 5000 years of domestication, great effort has been made to increase cocoon shell weight (CSW). However, silk yield is a complex trait controlled by quantitative trait loci (QTLs). From these QTLs, BmAbl1 tyrosine kinase, which is located at chromosome 1, is considered to be closely related to CSW. In our study, the functional loss of BmAbl1 led to altered glutathione metabolism, which ultimately affects the amino acid synthesis and metabolic pathway, impairing silk fibroin protein synthesis. We further investigated the role of BmAbl1 in regulating silk fibroin secretion. A new perspective was taken on factors affecting silk fibroin synthesis. This provides a new idea to improve silk fibroin yield. It lays the groundwork for improving silk yield in the future. Abstract Bombyx mori, domesticated from wild silkworms, is an economic insect that feeds on mulberry leaves and produces silk. In the current study, we demonstrated the contribution of BmAbl1 in silk protein synthesis. The inhibition and knockout of BmAbl1 can reduce the larva weight and CSW. The effect on CSW of BmAbl1 is not on the transcriptional level, but on the translational level. RNA-sequencing data suggested that amino acid synthesis and the metabolism process had a great difference between the BmAbl1- and Control strain, particularly glutathione metabolism. An abnormality in glutathione metabolism led to the reduction of free glycine and serine content, which are the main components of fibroin protein. Finally, fibroin protein synthesis has been reduced, including fibroin-heavy chain, fibroin-light chain, and p25 protein. This finding brought to light the role of BmAbl1 in the silk protein synthesis process.
Effect of Mycotoxin Cytochalasin A on Photosystem II in Ageratina adenophora

Biological herbicides have received much attention due to their abundant resources, low development cost, unique targets and environmental friendliness. This study reveals some interesting effects of mycotoxin cytochalasin A (CA) on photosystem II (PSII). Our results suggested that CA causes leaf lesions on Ageratina adenophora due to its multiple effects on PSII. At a half-inhibitory concentration of 58.5 μΜ (I50, 58.5 μΜ), the rate of O2 evolution of PSII was significantly inhibited by CA. This indicates that CA possesses excellent phytotoxicity and exhibits potential herbicidal activity. Based on the increase in the J-step of the chlorophyll fluorescence rise OJIP curve and the analysis of some JIP-test parameters, similar to the classical herbicide diuron, CA interrupted PSII electron transfer beyond QA at the acceptor side, leading to damage to the PSII antenna structure and inactivation of reaction centers. Molecular docking model of CA and D1 protein of A. adenophora further suggests that CA directly targets the QB site of D1 protein. The potential hydrogen bonds are formed between CA and residues D1-His215, D1-Ala263 and D1-Ser264, respectively. The binding of CA to residue D1-Ala263 is novel. Thus, CA is a new natural PSII inhibitor. These results clarify the mode of action of CA in photosynthesis, providing valuable information and potential implications for the design of novel bioherbicides.
Detection, Tracking and Analysis of Turbulent Spots and Other Coherent Structures in Unsteady Transition

Transition on turbine blades is an important factor in the determination of eventual flow separation and engine performance. The phenomenon is strongly affected by unsteady flow conditions (wake passing). It is likely that some physics of unsteadiness should be included in advanced models, but it is unclear which properties would best embody this information. In this paper, we use a GEAE experimental database in unsteady transition to test some tools of spot identification, tracking and characterization. In this preliminary study, we identify some parameters that appear to be insensitive to wake passing effects, such as convection speed, and others more likely to require unsteady modeling. The main findings are that wavelet duration can be used as a measure of spot size, and that spot energy density is most closely correlated to the wake passing. The energy density is also correlated to spot size, but spot size appears unrelated to the phase angle. Recommendations are made for further study.
Texas Spectroscopic Search for Lyα Emission at the End of Reionization. II. The Deepest Near-infrared Spectroscopic Observation at z ≳ 7

Realizing the utility of Lyα emission to trace the evolution of the intergalactic medium (IGM) during the epoch of reionization requires deep spectroscopy across the boundary of optical and near-infrared (NIR) spectrographs at z ∼ 7.2 when Lyα emission is at ∼1 μm. Our Texas Spectroscopic Search for Lyα Emission at the End of Reionization includes 18 nights of deep spectroscopic observations using the Keck DEIMOS (optical) and MOSFIRE (NIR) spectrographs. Within this data set we observe Lyα emission from 183 photometric-redshift-selected galaxies at z = 5.5–8.3 from the Cosmic Assembly Near infrared Deep Extragalactic Legacy Survey. Our overlapping MOSFIRE observations, over 84 galaxies in total, provide the deepest NIR spectroscopic data yet obtained for Lyα from galaxies z > 7, with >16 hr integration time for four observed galaxies. Here we analyze these four targets, and we report the discovery of a new z = 7.60 Lyα detection as well as provide an updated observation of the previously confirmed z = 7.51 Lyα emission from Finkelstein et al. with a ∼3× longer exposure time. Our analysis of these Lyα emission-line profiles reveals a significant asymmetric shape. The detection of Lyα from two out of three bright sources (MUV < −20.25) could imply that these bright galaxies inhabit ionized bubbles in a partially neutral IGM, although deeper exposures may reveal Lyα emission in the fainter source.
Heparanase Increases Podocyte Survival and Autophagic Flux after Adriamycin-Induced Injury

The kidney glomerular filtration barrier (GFB) is enriched with heparan sulfate (HS) proteoglycans, which contribute to its permselectivity. The endoglycosidase heparanase cleaves HS and hence appears to be involved in the pathogenesis of kidney injury and glomerulonephritis. We have recently reported, nonetheless, that heparanase overexpression preserved glomerular structure and kidney function in an experimental model of Adriamycin-induced nephropathy. To elucidate mechanisms underlying heparanase function in podocytes—key GFB cells, we utilized a human podocyte cell line and transgenic mice overexpressing heparanase. Notably, podocytes overexpressing heparanase (H) demonstrated significantly higher survival rates and viability after exposure to Adriamycin or hydrogen peroxide, compared with mock-infected (V) podocytes. Immunofluorescence staining of kidney cryo-sections and cultured H and V podocytes as well as immunoblotting of proteins extracted from cultured cells, revealed that exposure to toxic injury resulted in a significant increase in autophagic flux in H podocytes, which was reversed by the heparanase inhibitor, Roneparstat (SST0001). Heparanase overexpression was also associated with substantial transcriptional upregulation of autophagy genes BCN1, ATG5, and ATG12, following Adriamycin treatment. Moreover, cleaved caspase-3 was attenuated in H podocytes exposed to Adriamycin, indicating lower apoptotic cell death in H vs. V podocytes. Collectively, these findings suggest that in podocytes, elevated levels of heparanase promote cytoprotection.
First investigation of the local environment of europium in a strontium phosphate glass using molecular dynamics simulations

Abstract Phosphate glasses are characterized by properties distinguished by comparison with those of others such as borates, silicates, and tellurides that can be used in many fields such as optics, electronics, medicine, environmental protection, etc. This study aims to discover the effect of the europium dopant on the structural properties of glasses with 65% P2O5 – (35-x) % SrO – x% Eu3O2 (where x = 0.5, 1, 1.5, 2 mol at. %) using molecular dynamics simulations. The density of simulated glasses was found to increase from 2.784 to 2.860 g/cm3 according to the gradual increase in the europium content. The Eu-O distances and coordination numbers are found to be in the ranges of 2.18–2.21 Å and 6.59–6.79, respectively. The Sr-O coordination numbers were found to decrease from 7.30 to 6.55 with an increase in the europium content in the phosphate glasses. The coordination of the Eu-Eu pair increases from 0.07 to 0.23 with increasing europium concentration in phosphate glasses, but it remains weak, which is a sign of good solubility of europium in the glass matrix, as expected by experiments and the literature. Studies of the cluster statistics in the simulated glasses demonstrate that most europium atoms are found isolated or in a doublet. GRAPHICAL ABSTRACT