Miracle-dz/UniFAR-FTUs huggingface dataset:
Closed-loop identification and tracking control of Lagrangian systems under input constraints

In this paper global tracking and parameter convergence are proven for an adaptive control algorithm with independently saturated proportional and derivative terms through a persistency of excitation condition, while guaranteeing the inputs to never reach their natural saturation limit. As far as the authors are aware this is the first work that achieves globally the motion control objective and system identification, avoiding actuator saturation.
Clathrin-coated vesicular transport of secretory proteins during the formation of ACTH-containing secretory granules in AtT20 cells

We have studied by electron microscopy and immunocytochemistry the formation of secretory granules containing adrenocorticotropic hormone (ACTH) in murine pituitary cells of the AtT20 line. The first compartment in which condensed secretory protein appears is a complex reticular network at the extreme trans side of the Golgi stacks beyond the TPPase-positive cisternae. Condensed secretory protein accumulates in dilated regions of this trans Golgi network. Examination of en face and serial sections revealed that "condensing vacuoles" are in fact dilations of the trans Golgi network and not detached vacuoles. Only after presumptive secretory granules have reached an advanced stage of morphological maturation do they detach from the trans Golgi network. Frequently both the dilations of the trans Golgi network containing condensing secretory protein and the detached immature granules in the peri-Golgi region have surface coats which were identified as clathrin by immunocytochemistry. Moreover both are the site of budding (or fusion) of coated vesicles, some of which contain condensed secretory protein. The mature granules below the plasma membrane do not, however, have surface coats. Immunoperoxidase labeling with an antiserum specific for ACTH and its precursor polypeptide confirmed that many of the coated vesicles associated with the trans Golgi network contain ACTH. The involvement of the trans Golgi network and coated vesicles in the formation of secretory granules is discussed.
Analysis of projects planning and monitorization and control techniques and tools for their use in SMEs

Software production is an increasingly important economic activity; in Latin America, this sector is made up of 99% of SMEs. This highlights the importance of the implementation of Software Engineering best practices in SMEs to improve their productivity. The goal of this article is to present an analysis of project management techniques and tools. The analysis focuses on project planning, project monitoring and control, as support of SMEs in the selection of those techniques and tools appropriate to their environment, so that, the use of and implementation of best practices is promoted.
A fine instrument: two nation‐building strategies in post‐Soviet Belarus*

Abstract. This article pursues two aims. On the empirical level, it challenges the view of Belarus as a ‘denationalised’, or ‘failed’ nation, and exposes the country as an area of intensive nation-building. The article demonstrates that, unlike most post-communist states, two versions of national identity have been advanced in Belarus since 1989, with divergent results for their proponents. On the theoretical level, such an atypical experience places qualifications on the instrumentalist approach, that regards nation-building as a political tool. The analysis of identity creation in Belarus suggests that nation-building as a political strategy may be limited by the existing attitudes in the society in question, the socio-economic structures, as well as by the influence of foreign actors.
Using formal specifications to support testing

Formal methods and testing are two important approaches that assist in the development of high-quality software. While traditionally these approaches have been seen as rivals, in recent years a new consensus has developed in which they are seen as complementary. This article reviews the state of the art regarding ways in which the presence of a formal specification can be used to assist testing.
Parents' emotional reactions related to different prospects for the survival of their children with cancer

The emotional reactions and concerns of parents of children with cancer who had different prognoses for survival were investigated. Parents (84 mothers and 79 fathers) of 84 children with cancer who were in remission or had relapsed participated in the study. The mothers and fathers of children who had relapsed reported more feelings of helplessness and uncertainty and also reported their fears more often concerning their child's chances of survival than did the mothers and fathers of children whose cancer was in remission. Mothers of children with a relapse also reported more depression and anxiety. The problems of fathers of children who had relapsed were revealed only with the use of an illness-related questionnaire. Time since diagnosis did not change the emotional reactions of any of the parents. The authors conclude that the parents of children whose cancer has relapsed should be carefully monitored.
TADtool: visual parameter identification for TAD-calling algorithms

Abstract Summary: Eukaryotic genomes are hierarchically organized into topologically associating domains (TADs). The computational identification of these domains and their associated properties critically depends on the choice of suitable parameters of TAD-calling algorithms. To reduce the element of trial-and-error in parameter selection, we have developed TADtool: an interactive plot to find robust TAD-calling parameters with immediate visual feedback. TADtool allows the direct export of TADs called with a chosen set of parameters for two of the most common TAD calling algorithms: directionality and insulation index. It can be used as an intuitive, standalone application or as a Python package for maximum flexibility. Availability and implementation: TADtool is available as a Python package from GitHub (https://github.com/vaquerizaslab/tadtool) or can be installed directly via PyPI, the Python package index (tadtool). Contact: kai.kruse@mpi-muenster.mpg. de, jmv@mpi-muenster.mpg. de Supplementary information: Supplementary data are available at Bioinformatics online.
‘A Person is a Person Because of Others’: Challenges to Meanings of Discipline in South African and UK Schools

In this article the authors consider current understandings of discipline in schools in the United Kingdom and South Africa. The concern is with exploring the discipline/punishment/power nexus in education in both countries; with how reductionist versions of discipline as authoritarianism interweave with views about the aims and perceived need for punishment in schools, and how this is driven by perceptions of a need to maintain control or power over young people, often viewed as a ‘generation of suspects’. The authors argue that a restorative approach can be used to build more inclusive school communities where staff and students negotiate new meanings of discipline and power. Some of the key challenges associated with a restorative approach are then explored in detail and the notion of ubuntu – ‘A person is a person because of others' – strongly associated with the new South Africa and its reassertion of traditional principles and values, is suggested as a useful compass for future development in both countries. In very different contexts, but facing many of the same challenges, the authors ask: What can the United Kingdom learn from South Africa and what can South Africa learn from the United Kingdom?
Introduction: New media: Mobile advertising and marketing

For many consumers worldwide, cell phones, iPods, PDAs, and instant messaging have become indispensable, yet marketers are still learning how to use these media. As ownership of hand-held devices and other new technologies becomes increasingly widespread, it is important to examine advertising and marketing via the use of short message service (SMS) text messages, multimedia message service, WiFi, hotspots, and additional new applications such as Bluetooth. Notably, the growth of these technologies has not been confined to any one part of the world. In fact, the use of SMS took off most quickly in East Asian countries such as South Korea and Japan, as well as parts of Europe and, more recently, the United States. The papers in this special issue are designed to provide insight into consumer adoption and use of mobile media, as well as into marketers’ use of mobile media. Notably, a high number of submissions were received from many parts of the world, and the papers represented validate such variety. The table of contents in this issue reveals an eclectic set of papers from all parts of the globe where mobile commerce has made substantial inroads. This is most fortunate in terms of examining whether patterns of use and adoption can be generalized, and also in helping to determine which research findings apply cross-culturally. In the first article, Okazaki examines the factors associated with effectively generating SMS “word of mouth” communication through advertising. The commitment-value paradigm is used to develop a model that examines individual psychological characteristics and the influence they may have in perceiving value in a campaign and subsequently participating in it. The methodology for testing the model involved sending a text message to a group of young Japanese
Actin-specific ADP-ribosyltransferase produced by a Clostridium difficile strain

By screening possible ADP-ribosyltransferase activities in culture supernatants from various Clostridium species, we have found one Clostridium difficile strain (CD196) (isolated in our laboratory) that is able to produce, in addition to toxins A and B, a new ADP-ribosyltransferase that was shown to covalently modify cell actin as Clostridium botulinum C2 or Clostridium perfringens E iota toxins do. The molecular weight of the CD196 ADP-ribosyltransferase (CDT) was determined to be 43 kilodaltons, and its isoelectric point was 7.8. No cytotoxic activity on Vero cells or lethal activity upon injection in mice was associated with this enzyme. CDT was neither related to C. difficile A or B toxins nor to C. botulinum C2 toxin component I. However, Vero cells cultivated in the presence of C. difficile B toxin had a lower amount of actin able to be ADP-ribosylated by CDT or C2 toxin in vitro. Antibodies raised against CDT reacted by immunoblot analysis with a 43-kilodalton protein of C. perfringens type E culture supernatant producing the iota toxin.
Brief report: deficiency of pulmonary surfactant protein B in congenital alveolar proteinosis.

Congenital pulmonary alveolar proteinosis is an uncommon cause of respiratory failure in full-term newborns1–4. Although its histopathological appearance is similar to that of the alveolar proteinosis observed in older children and adults,5 the congenital form of the illness follows a different clinical course. All reported infants with congenital alveolar proteinosis have died within the first year of life despite maximal medical therapy. The incidence and cause of congenital alveolar proteinosis are unknown. Familial cases have been reported, and it has been speculated that the cause is an inborn error of surfactant metabolism4. In this report we describe .
Within-Word vs. Across-Word Decoding for Online Speech Recognition

In this paper we describe methods for improving the RWTH German speech recognizer used within the VERBMOBIL project. In particular, we present acceleration methods for the search based on both within-word and across-word phoneme models. The recognizer in the VERBMOBIL project is used in an online environment. We will discuss some incremental methods to reduce the response time of an on-line speech recognizer. We present experimental off-line results for the VERBMOBIL task, a German spontaneous speech corpus, and report on word error rates and real time performance of the search for both within-word and across-word phoneme models.
The PLC UML State-chart design pattern

We developed an UML-State-charts Object Oriented Design Pattern for PLCs IEC61131-3. This PLC UML-State-chart Design Pattern aims to explore the advantage of Object Oriented Programming by IEC61131-3 in PLCs, and to provide a direct map of UML State-chart to PLC code. We illustrates the design pattern and its use through UML Class diagrams and an application example. This Design Pattern can be used to reduce the development time of State-charts in automation software. It can also lead towards further investigations in PLC Design Patterns that may improve the whole development of automation software.
Antitumor active fucoidan from the brown seaweed, umitoranoo (Sargassum thunbergii).

Neutral and acidic polysaccharides and their protein complexes were fractionated and purified from the brown seaweed umitoranoo (Sargassum thunbergii) by fractional extraction, iron-exchange chromatography, and gel filtration. Thirty-one polysaccharide fractions were obtained and tested for antitumor activity in mice with Ehrlich carcinoma transplanted i.p. Two of the fractions, GIV-A ([alpha]25D -127 degrees and mol. wt., 19,000) and GIV-B ([alpha]25D -110 degrees and mol. wt., 13,500) had such activity. On the basis of chemical and spectral analyses, these compounds were found to be a fucoidan or L-fucan containing approx. 30% sulfate ester groups per fucose residue, about 10% uronic acid, and less than 2% protein.
Effectiveness of an injury prevention programme for adult male amateur soccer players: a cluster-randomised controlled trial

Background The incidence rate of soccer injuries is among the highest in sports, particularly for adult male soccer players. Purpose To investigate the effect of the ‘The11’ injury prevention programme on injury incidence and injury severity in adult male amateur soccer players. Study design Cluster-randomised controlled trial. Methods Teams from two high-level amateur soccer competitions were randomly assigned to an intervention (n=11 teams, 223 players) or control group (n=12 teams, 233 players). The intervention group was instructed to perform The11 in each practice session during one soccer season. The11 focuses on core stability, eccentric training of thigh muscles, proprioceptive training, dynamic stabilisation and plyometrics with straight leg alignment. All participants of the control group continued their practice sessions as usual. Results In total, 427 injuries were recorded, affecting 274 of 456 players (60.1%). Compliance with the intervention programme was good (team compliance=73%, player compliance=71%). Contrary to the hypothesis, injury incidences were almost equal between the two study groups: 9.6 per 1000 sports hours (8.4–11.0) for the intervention group and 9.7 (8.5–11.1) for the control group. No significant differences were found in injury severity, but a significant difference was observed in the location of the injuries: players in the intervention group sustained significantly less knee injuries. Conclusions This study did not find significant differences in the overall injury incidence or injury severity between the intervention and control group of adult male soccer players. More research is recommended, focusing on injury aetiology and risk factors in adult male amateur soccer players.
Collaborative multi-agent systems for construction equipment based on real-time field data capturing

This paper proposes collaborative multi-agent systems for real-time monitoring and planning on construction sites. A multi-agent system framework is discussed to support construction equipment operators by using agents, wireless communication, and field data capturing technologies. Data collected from sensors attached to the equipment, in addition to an up-to-date 3D model of the construction site, are processed by the multi-agent system to detect any possible collisions or other conflicts related to the operations of the equipments, and to generate a new plan in real time. The potential advantages of the proposed approach are: more awareness of dynamic construction site conditions, a safer and more efficient work site, and a more reliable decision support based on good communications.
[Study on risk factors of depressive and/or anxiety symptoms in patients with coronary heart disease in general hospitals of urban China].

OBJECTIVE To explore the risk factors of depressive and/or anxiety symptoms in patients with coronary heart disease (CHD) in the general hospital of main cities in China. METHODS A hospital-based cross-sectional study was conducted in four main cities in China in 2004. 359 CHD patients were recruited continually during six months from the outpatient and inpatient department of 7 tertiary hospitals. Face-to-face interview was used in data collection together with the self-completed HAD scale for depressive and/or anxiety symptom screening. Multinomial Logistic Model was adopted in data analysis. RESULTS Among 359 CHD patients, 82 (22.8%) obtained a HAD score of 9 and above. Non-ambulatory patients had a statistically higher risk of depressive symptoms (OR = 17.996, 95 % CI:3.872 - 83.636); subjects younger than 65 years old, or having an education year equal or less than 9 year, or having a self-assessment of CHD deterioration had increased risk of anxiety symptoms with the ORs at 3.151 (95% CI: 1.151-8.629), 3.154(95% CI: 1.094-9.092) and 4.229 (95% CI: 1.396-12.809) respectively. Hospitalized (OR = 4.887, 95% CI: 1.711-13.960) and non-ambulatory (OR = 6.583, 95% CI: 2.776-15.612) CHD patients were more liable to suffer both depressive and anxiety symptoms. CONCLUSION It was noticeable to health care providers both in somatic disease care and mental health care that non-ambulatory status, younger than 65 years old, lower education level, felt deterioration of CHD and hospitalization were possible risk factors for depressive and/or anxiety symptoms in patients with CHD in general hospitals in urban China.
Provenance and Quality Control in Sensor Networks

Scientists and society increasingly rely on streaming data from electronic sensors to assess, model, and forecast environmental changes. Because analyses of time-series data require uninterrupted data streams or datasets, scientists regularly fill gaps in the data by substituting modeled values. As modeling increases in complexity, the provenance metadata needed to describe and define processes used to model data and create derived datasets quickly exceeds the capacity of individual flags or groups of flags to annotate individual data values. In theory, necessary provenance metadata could be captured in narrative form, but the time and effort required to do so are prohibitive. A system that can capture provenance metadata automatically and allow scientists to query them for useful details is what scientists really need. In this paper we describe a system that uses LittleJIL, a process programming language, to rigorously define modeling and data-derivation processes, and a mathematical graph structure – a Data Derivation Graph (DDG) – that precisely describes execution histories. Our system and approach support understanding the (potentially) different processes used to create data values, reasoning about the soundness of these processes, and helping to ensure that the data processing in sensor networks is reliable and reproducible. Keywords—provenance metadata, scientific workflow, sensor network, Little-JIL
Endangered outdoor recreation experiences: contextual development and lexicon.

Just as some species of plants and animals are endangered, some outdoor recreation opportunities are ‘endangered’ in that opportunities to participate in certain activities are becoming scarce and may eventually be permanently lost. The existence of these experiences is threatened by both alterations in the physical environment and by changing social and cultural pressures. The objective of this paper is to propose the application of ecological terms and concepts to develop a conceptual framework for managers and planners dealing with ‘endangered’ outdoor recreation experiences. Potential applications of the lexicon and conceptual approach presented in this paper are: to identify threats to the existence of opportunities for specific recreational experiences, and to provide policy-makers and planners with a systematic approach to setting priorities and developing management strategies to maintain or expand these opportunities. Such an approach may help insure the perpetuation of a diverse array of recreat.
Working Conditions, Socioeconomic Factors and Low Birth Weight: Path Analysis

Background In recent years, with socioeconomic changes in the society, the presence of women in the workplace is inevitable. The differences in working condition, especially for pregnant women, has adverse consequences like low birth weight. Objectives This study was conducted with the aim to model the relationship between working conditions, socioeconomic factors, and birth weight. Patients and Methods This study was conducted in case-control design. The control group consisted of 500 women with normal weight babies, and the case group, 250 women with low weight babies from selected hospitals in Tehran. Data were collected using a researcher-made questionnaire to determine mothers’ lifestyle during pregnancy with low birth weight with health-affecting social determinants approach. This questionnaire investigated women’s occupational lifestyle in terms of working conditions, activities, and job satisfaction. Data were analyzed with SPSS-16 and Lisrel-8.8 software using statistical path analysis. Results The final path model fitted well (CFI =1, RMSEA=0.00) and showed that among direct paths, working condition (β=-0.032), among indirect paths, household income (β=-0.42), and in the overall effect, unemployed spouse (β=-0.1828) had the most effects on the low birth weight. Negative coefficients indicate decreasing effect on birth weight. Conclusions Based on the path analysis model, working condition and socioeconomic status directly and indirectly influence birth weight. Thus, as well as attention to treatment and health care (biological aspect), special attention must also be paid to mothers’ socioeconomic factors.
The distinction between work pace and working hours in the measurement of quantitative demands at work

During recent years many researchers have criticized the widely used scales on psychological job demands. For instance, they comment that in most cases different types of demand seem to be mixed in one measure. In this paper we analyse the scale on quantitative job demands in the recently developed Copenhagen Psychosocial Questionnaire (COPSOQ), with special emphasis on Differential Item Functioning (DIF). DIF refers to basic differences between groups of respondents, which may affect how they respond to questionnaire items. The data material for our study comprised a representative sample of Danish employees. The respondents were categorized into 32 specific jobs according to the International Standard Classification of Occupations (ISCO 1968). We analysed DIF with respect to the respondents’ jobs with logistic regression analyses. These analyses showed that the items used in the original demand scale functioned very differently for different jobs in the population. The conclusion is that scales on quantitative demands are very sensitive to the choice of specific items. If many items on fast work pace and tempo are included in a scale, a number of blue-collar jobs will be identified as high-demand jobs. If, on the other hand, many questions on long working hours and overtime are included, the use of the scale will result in an entirely different picture. This issue has so far received little attention in occupational health psychology. The results have wide theoretical and methodological implications for research on quantitative job demands.