Miracle-dz/UniFAR-FTUs huggingface dataset:
Long-Term Followup of Anatomic Graduated Components Posterior Cruciate-Retaining Total Knee Replacement

The purpose of the current study was to evaluate the authors’ 15-year experience with the Anatomic Graduated Components total knee replacement. This is a report of the survivorship of 4583 Anatomic Graduated Component total knee arthroplasties. Kaplan-Meier survival analyses were performed with the end point defined as radiographic loosening, revision, or both. This end point was subdivided into the best case scenario in which it was assumed that all the patients lost to followup were doing well throughout the study and a worst case scenario in which it was assumed that all patients lost to followup had failed results at their last clinic visit. There were six (0.18%) femoral, 21 (0.46%) tibial, and 180 (4.2%) all-polyethylene patellar component failures secondary to aseptic loosening. All femoral components and 90% of the tibial components were revised; however, only 15 patellar components were revised. The clinical survival rate with revision of one or more of the components was 98.86% at 15 years. Despite having nearly flat-on-flat geometry and retaining the posterior cruciate ligament, which should increase the stresses in the polyethylene and at the bone-cement interface, this total knee replacement has proved to have minimal wear and excellent longevity with time. The authors think this is a result of the direct compression molded polyethylene articulation and the nonmodular configuration that incorporates metal backing on the tibial component and eliminates back-sided tibial component polyethylene wear.
NAPSS—a numerical analysis problem-solving system

The best tool for coordinating a large program design project is the computer itself. The programmer is on intimate terms with the computer. He uses it to create his product, to test his product, and to change his product. If he is one of many programmers, all working on a single program system, his activities blend with the activities of others at and within the computer. The very nature of program design is such that an automated management system, built within the object computer 1, can be extremely beneficial in coordinating program design. The Program Management System (PMS) has been designed with this thought in mind. The PMS is an automated system specifically organized to meet the design, coordination, and management information needs of today's large program production projects. Program designers enter actual design documentation into the PMS as their design progresses and selectively retrieve the documentation of others. The PMS is a tool in-line with the program development process. The use of the PMS today should help establish procedures which will lead to more systematic approaches to program development. This, in turn, will increase the usefulness of the PMS itself.
Affect and Deed: Developmental Changes in Infant Communication.

AUTHOR TITLE Adamson, Lauren Bakeman, Roger Affect and Deed: Developmental Changes in Infant Communication. 'SPONS AGENCY National Science Foundation, Washington, D.C. PUB DATE Mar 83 GRANT NSFBNS-8012068 NOTE llp. ; Paper presented at the Annual Meeting of the Southeastern Psychological Association (Atlanta, GA, March 23-26, 1983). PUB TYPE Reports Research/Technical (143) Speeches/Conference Papers (150)
Men, masculinity and male gender role socialisation : implications for men's mental health and psychological help seeking behaviour

The work comprises of three sections, Section A: Literature review This section reviews men's underutilisation of professional health care services and brings together the extant literature on men's help seeking for psychological difficulties. This is discussed specifically in relation to theories of male gender role socialisation and male development. Section B: Empirical Paper. Introduction: Men’s reluctance to access health care services has been under researched even though it has been identified as a potentially important predictor of poorer health outcomes among men. Male gender role socialisation and male development may be important in accounting for men’s underutilisation of mental health service in the UK. Method: A cross-sectional online survey was used to administer standardised self-report measures that were subject to regression analysis. Five hundred and eighty-one men from the UK general population completed the survey and 434 participants formed the final regression model sample. Results: Men who score higher on measures of traditional masculine ideology, normative alexithymia and fear of intimacy reported more negative attitudes towards seeking professional psychological help. Normative alexithymia accounted for the variance in help seeking previously observed by fear of intimacy during regression modelling. Sexuality and ethnicity also significantly accounted for a proportion of unique variance in men’s help seeking attitudes. People who had received previous support from a mental health professional showed more positive attitudes towards seeking psychological help. Conclusions: Men’s attitudes towards seeking psychological help were closely related to traditional masculine ideology and normative alexithymia. A degree of content or construct overlap may exist between normative alexithymia and fear of intimacy in men. Limitations of this study and implications for future research are discussed. Section C: Critical Review. This section provides critical appraisal and reflection on the study and research process. Personal learning is discussed alongside clinical implications and ideas for further research.
Strongly Privacy-Preserving Communication Protocol for VANETs

Vehicular ad hoc networks (VANETs) are advanced instances of mobile ad hoc networks with the aim of enhancing the safety and efficiency of road traffic. The basic idea is to allow arbitrary vehicles to broadcast ad hoc messages (e.g. Traffic accident notifications) to other vehicles and remind drivers to change their routes immediately or slow down to avoid dangers. However, some concerns on security and privacy are also raised in this environment. Messages should be signed and verified before they are trusted while the real identities of vehicles should not be revealed to guarantee source privacy, but they must be still traceable when VANETs were abused (e.g. Sending a fake message). Many related works have been presented in the literature so far. They can be generally divided into two constructions, where one is based on pseudonymous authentication and the other is based on group signatures. However, both of the two constructions have some drawbacks. In a pseudonymous-authentication-based scheme, a large revocation list is usually transmitted among vehicles. A group-signature-based scheme needs a large amount of computations for revocation checking. Furthermore, most of the previous schemes cannot support privacy preservation between roadside units (RSUs) and vehicles. Consequently, in this paper, we come up with a provably secure and strong privacy preserving protocol based on the blind signature technique to guarantee privacy and fulfill other essential security requirements in the vehicular communication environment. Furthermore, compared with other similar works, we offer an efficient tracing mechanism to trace and revoke the vehicles which abused the VANETs. Finally, we provide security analysis to show that our proposed scheme is secure.
PET sinogram denoising by block-matching and 3D filtering

We consider the denoising of noisy positron emission tomography (PET) sinograms by sparse 3D transform domain collaborative filtering. The filtering operation is realized by block-matching and 3D (BM3D) filtering algorithm that groups similar 2D sinogram fragments into 3D groups and filters each group by collaborative filtering. This filtering jointly filters the similar blocks in the transform domain and offers a way for efficient denoising while preserving essential information of each sinogram fragment. The obtained results are compared with conventional radial filtering and stackgram filtering that utilizes an intermediate stage between sinogram and image domains, called stackgram domain. Both quantitative and qualitative comparisons show that the proposed approach to filter the sinogram with BM3D filter outperforms the other filtering methods.
Transferring responsibility and accountability in maternity care: clinicians defining their boundaries of practice in relation to clinical handover

Objective This exploratory study reports on maternity clinicians’ perceptions of transfer of their responsibility and accountability for patients in relation to clinical handover with particular focus transfers of care in birth suite. Design A qualitative study of semistructured interviews and focus groups of maternity clinicians was undertaken in 2007. De-indentified data were transcribed and coded using the constant comparative method. Multiple themes emerged but only those related to responsibility and accountability are reported in this paper. Setting One tertiary Australian maternity hospital. Participants Maternity care midwives, nurses (neonatal, mental health, bed managers) and doctors (obstetric, neontatology, anaesthetics, internal medicine, psychiatry). Primary outcome measures Primary outcome measures were the perceptions of clinicians of maternity clinical handover. Results The majority of participants did not automatically connect maternity handover with the transfer of responsibility and accountability. Once introduced to this concept, they agreed that it was one of the roles of clinical handover. They spoke of complete transfer, shared and ongoing responsibility and accountability. When clinicians had direct involvement or extensive clinical knowledge of the patient, blurring of transition of responsibility and accountability sometimes occurred. A lack of ‘ownership’ of a patient and their problems were seen to result in confusion about who was to address the clinical issues of the patient. Personal choice of ongoing responsibility and accountability past the handover communication were described. This enabled the off-going person to rectify an inadequate handover or assist in an emergency when duty clinicians were unavailable. Conclusions There is a clear lack of consensus about the transition of responsibility and accountability—this should be explicit at the handover. It is important that on each shift and new workplace environment clinicians agree upon primary role definitions, responsibilities and accountabilities for patients. To provide system resilience, secondary responsibilities may be allocated as required.
Review on Design and Control Aspects of Robotic Shoulder Rehabilitation Orthoses

Robotic rehabilitation devices are more frequently used for the physical therapy of people with upper limb weakness, which is the most common type of stroke-induced disability. Rehabilitation robots can provide customized, prolonged, intensive, and repetitive training sessions for patients with neurological impairments. In most cases, the robotic exoskeletons have to be aligned with the human joints and provide natural arm movements. This is a challenging task to achieve for one of the most biomechanically complex joints of human body, i.e., the shoulder. Therefore, specific considerations have been made in the development of various existing robotic shoulder rehabilitation orthoses. Different types of actuation, degrees of freedom (DOFs), and control strategies have been utilized for the development of these shoulder rehabilitation orthoses. This paper presents a comprehensive review of these shoulder rehabilitation orthoses. Recent advancements in the mechanism design, their advantages and disadvantages, overview of hardware, actuation system, and power transmission are discussed in detail with the emphasis on the assisted DOFs for shoulder motion. A brief overview of control techniques and clinical studies conducted with the developed robotic shoulder orthoses is also presented. Finally, current challenges and directions of future development for robotic shoulder rehabilitation orthoses are provided at the end of this paper.
VALIDATION OF THE MICROSCOPIC TRAFFIC FLOW MODEL VISSIM IN DIFFERENT REAL-WORLD SITUATIONS

This paper presents the possibilities of validating the microscopic traffic flow simulation model VISSIM, both on a microscopic and a macroscopic level. VISSIM implements a psycho-physical car-following model and thus provides a very realistic driving behavior. The complex model offers, but also requires, many model parameters that can be calibrated using measurement data from driving experiments. Some examples of how certain parameters influence driving behavior are given by comparing a simulated approach-and-following-process with records from a probe vehicle. The model parameters can be adjusted to reflect different traffic situations. As examples, the model is validated using measurement data taken from a German freeway and from a US freeway, where driver behavior as well as traffic regulations are substantially different
On sample-path staleness in lazy data replication

We analyze synchronization issues arising between two stochastic point processes, one of which models data churn at an information source and the other periodic downloads from its replica (e.g., search engine, web cache, distributed database). Due to lazy (pull-based) synchronization, the replica experiences recurrent staleness, which translates into some form of penalty stemming from its reduced ability to perform consistent computation and/or provide up-to-date responses to customer requests. We model this system under non-Poisson update/refresh processes and obtain sample-path averages of various metrics of staleness cost, generalizing previous results and exposing novel problems in this field.
Ophthalmic Artery Flow and Cognitive Performance in Patients withCarotid Artery Stenosis

The circle of Willis is regarded as the primary collaterals in patients with severe carotid artery stenosis (CAS), while the secondary collaterals from the reversed ophthalmic artery (OA) flow would be recruited when the primary collaterals are inadequate to maintain cerebral perfusion. Even though some reports suggest patients with reversed OA flow are more vulnerable to cerebral ischemic injury, whether reversed OA flow is adequate to maintain cognitive function or can be employed as a surrogate marker of cognitive impairment remains elusive. The purpose of this article is to review the dynamic behavior of collateral flow and to assess the relationship between OA hemodynamics, cerebral perfusion and cognitive performance in patients with CAS. There is evidence that the OA flow patterns behave dynamically according to the hemodynamic, metabolic, and neural demands. Patients with reversed OA flow have compensatory increased cerebral blood volume and timerelated perfusion parameters, while cerebral blood flow usually remains unchanged. Despite of the evidence having been scarce, the associations between hemodynamics of OA flow and cognitive performance have been observed in several recent studies. Furthermore, our previous study demonstrated a tendency for specific cognitive impairment observed in patients with reversed OA flow, depending on the side of reversed OA flow. However, the impacts of the OA flow patterns on cognition may be modified when the other pathogenic factors of stroke are taken into account. Concurrent application of multimodality neuroimaging findings about perfusion status and neural activities will greatly enhance our understanding of the relationships between the hemodynamics of OA flow and cognition.
A Statistical Process Monitoring Perspective on “ Big Data ”

As our information infrastructure evolves, our ability to store, extract, and analyze data is rapidly changing. Big data is a popular term that is used to describe the large, diverse, complex and/or longitudinal datasets generated from a variety of instruments, sensors and/or computer-based transactions. The term big data refers not only to the size or volume of data, but also to the variety of data and the velocity or speed of data accrual. As the volume, variety, and velocity of data increase, our existing analytical methodologies are stretched to new limits. These changes pose new opportunities for researchers in statistical methodology, including those interested in surveillance and statistical process control methods. Although it is well documented that harnessing big data to make better decisions can serve as a basis for innovative solutions in industry, healthcare, and science, these solutions can be found more easily with sound statistical methodologies. In this paper, we discuss several big data applications to highlight the opportunities and challenges for applied statisticians interested in surveillance and statistical process control. Our goal is to bring the research issues into better focus and encourage methodological developments for big data analysis in these areas.
Web Services and IT Management

Platform and programming language independence, coupled with industry momentum, has made Web services the technology of choice for most enterprise integration projects. Their close relationship with SOA (service-oriented architecture) has also helped them gain mindshare. Consider this definition of SOA: "An architectural style whose goal is to achieve loose coupling among interacting software agents. A service is a unit of work done by a service provider to achieve desired end results for a service consumer. Both provider and consumer are roles played by software agents on behalf of their owners. " Although SOA doesn’t mandate Web services, its emphasis on loose coupling requires use of something with the characteristics of Web services.
The Watchman FLX – a new device for left atrial appendage occlusion – design, potential benefits and first clinical experience

Although convincing data showed that left atrial appendage (LAA) occlusion could be used as an alternative to oral anticoagulants, LAA occlusion has emerged as a common procedure for stroke prevention in patients with atrial fibrillation and absolute or relative contraindications for oral anticoagulation in many European centers, based on current recommendations of the European Society of Cardiology. The efficacy and safety of the current generation Watchman LAA Closure System was established in two large randomized clinical trials (PROTECT AF, PREVAIL [1, 2]) and several prospective registries (CAP, ASAP, EWOLUTION [3–5]).
HENDERSON ' S APPROACH TO VARIANCE COMPONENTS ESTIMATION FOR UNBALANCED DATA UDC

The analysis of variance is a frequently used technique of data analysing and probably the most used statistical method in 20th century. However, there are a lot of ambiguities in the interpretation of particular aspects. The aim of this text is an explanation of one of the fundamental parts of this method the variance components estimation. Namely, by calculating variability in observations we can divide their variance into parts which correspond to the factors we examine, and that means that the subject of study are the variance components. This text is a presentation of Henderson's method for variance components estimation in models of analysis of variance.
Nanoscale easy tear process for ultra-fast responsive colloidal crystal-PDMS composite VOCs sensors

In this study, we propose an ultra-fast responsive PC based volatile organic compounds (VOCs) sensor using a nanoscale easy tear process inspired by commercially available ‘easy tear package’. Colloidal crystal-polydimethylsiloxane (PDMS) composite can be realized through nanoscale tear propagation along the interface between the outer surface of crystallized nanoparticles and bulk PDMS. Not only cuboid but also dome shaped colloidal crystal-PDMS composite is successfully obtained using the assembled nanoparticles constructed by wettability contrast patterning or inkjet printing. The response time for VOCs detection is dramatically improved by allowing the direct contact with VOCs because of removing the residual on colloidal crystals perfectly.
La explicación científica: Estudios sobre la Filosofía de la ciencia

Las ciencias pueden explicar, mas no pueden explicarse, y este es un debate que tradicionalmente ha quedado a cargo de la filosofia de la ciencia. Es en este ambito donde se desarrolla el presente libro, que ofrece a su vez cuatro grandes nucleos tematicos: coafirmacion, induccion y creencia racional; concepciones de la significacion cognitiva; estructura y funcion de las teorias y los conceptos cientificos; y expliacion cientifica. Para hablarnos de este tema, el autor explora algunos de los aspectos mas importantes de las ciencias naturales y sociales, asi como de su historiografia, y presenta dos modelos basicos de hechos explicativos, analiza su solidez y examina en que medida iluminan la estructura y el fundamento de los distintos tipos de interpretacion e investigacion. El resultado es un texto que interesara tanto estudiantes y profesionales de la filosofia como a sociologos, naturalistas e historiadores preocupados por los aspectos metodologicos y filosoficos de sus disciplinas.
An overview of Lutess a specification-based tool for testing synchronous software

Test data generation and test execution are both time-consuming activities when done manually. Automated testing methods promise to save a great deal of human effort. This especially applies to reactive programs which have complex behaviour over time and which require long test sequences. We present Lutess, a testing environment for synchronous reactive software. Lutess produces automatically and dynamically test data with respect to some environment constraints of the program under test. Moreover, it allows to trace the test execution and spot the situations where the program violates its properties. Lutess offers several specification-based testing methods. They aim at simulating more realistic environment behaviours, producing relevant data to test thoroughly a given property or driving the program under test into interesting situations. To produce the test data, the methods use different types of guides: statistical distribution of the input generation, properties, or behavioural patterns. Lutess proved to be powerful and easy to use in industrial case studies. Lutess won the Best Tool Award of the first Feature Interaction Detection Contest. The tool is described from a practical point of view.
Evolutionary bet-hedging in the real world: empirical evidence and challenges revealed by plants

Understanding the adaptations that allow species to live in temporally variable environments is essential for predicting how they may respond to future environmental change. Variation at the intergenerational scale can allow the evolution of bet-hedging strategies: a novel genotype may be favoured over an alternative with higher arithmetic mean fitness if the new genotype experiences a sufficiently large reduction in temporal fitness variation; the successful genotype is said to have traded off its mean and variance in fitness in order to ‘hedge its evolutionary bets’. We review the evidence for bet-hedging in a range of simple plant systems that have proved particularly tractable for studying bet-hedging under natural conditions. We begin by outlining the essential theory, reiterating the important distinction between conservative and diversified bet-hedging strategies. We then examine the theory and empirical evidence for the canonical example of bet-hedging: diversification via dormant seeds in annual plants. We discuss the complications that arise when moving beyond this simple case to consider more complex life-history traits, such as flowering size in semelparous perennial plants. Finally, we outline a framework for accommodating these complications, emphasizing the central role that model-based approaches can play.