Miracle-dz/UniFAR-FTUs huggingface dataset:
Motivations for participation in physical activity across the lifespan

This investigation explored motivations for engaging in physical activity and how they varied across the lifespan. A total of 1,885 individuals completed a comprehensive questionnaire concerning personal style, activity interests, motives for exercising, and biosocial information as part of an initiative to improve physical activity advisement and programming. The first part of the research called for an exploratory factor analysis (EFA) of a 20-item measure of both intrinsic and extrinsic motivations related to participation in exercise, while the second was based in an analysis of differences on the EFA factor scores across five age groups: teens, 20s, 30s, 40s, and 50s+. EFA results suggested a four-factor (oblique rotation) solution that appeared to provide an adequate and generalizable map of intrinsic and extrinsic motivations for exercise. The factors were labeled as follows: mental toughness, toned and fit, fun and friends , and stress reduction. Not surprisingly, mean scores on toned and fit were the highest of the four factor means across all age groups. Univariate ANOVAs of age group differences were statistically significant for each of the four factors; moreover, all four factors showed statistically significant linear trends. Two factors, toned and fit and stress reduction, revealed higher motivation scores with increasing age, while the remaining two, mental toughness and fun and friends, exhibited declining scores with increasing age. These findings taken in the context of previous research on age-related motivational differences offered insights into current challenges for enhancing exercise participation, particularly for older individuals.
Supported Employment for Young Adults with Autism Spectrum Disorder: Preliminary Data

The purpose of this study was to examine the effects of supported employment in securing and maintaining competitive employment for people with autism spectrum disorder, a group that has typically been found to be underemployed or unemployed. This prospective study followed and collected data on 33 individuals with autism spectrum disorder as they progressed through a supported employment model, working one-on-one with an employment specialist. Of the 33 individuals included in the study, 27 successfully obtained competitive employment, with a total of 29 positions secured. The successful results were achieved through the use of a supported employment model and skilled employment specialists who were able to provide a high level of social supports and compensatory training strategies for skill acquisition. Specifically, employment specialists supported individuals through four steps of an individualized supported employment model: (a) the development of a jobseeker profile and assessment, (b) guiding the job development and career search, (c) conducting job site training, and (d) designing long-term supports to promote job retention. The multitude and variance of specific methods and strategies used in each case to execute these key steps of the supported employment model accurately reflect an emphasis on a highly individualized approach. Although the outcomes of this preliminary study were positive in terms of employment outcomes, further research remains to be conducted.
A new locus for autosomal recessive RP (RP29) mapping to chromosome 4q32-q34 in a Pakistani family.

PURPOSE To map the disease locus in a six-generation, consanguineous Pakistani family with autosomal recessive retinitis pigmentosa (arRP). All affected individuals had pigmentary retinopathy associated with symptoms of night blindness and the loss of peripheral visual fields by the age of 20 years, loss of central vision between the ages of 25 and 30 years, and complete blindness between the ages of 40 and 50 years. METHODS Genomic DNA from family members was typed for alleles at known polymorphic genetic markers using polymerase chain reaction. Alleles were assigned to individuals, which allowed calculation of LOD scores using the programs Cyrillic (http://www.cyrillicsoftware.com) and MLINK (Cherwell Scientific Publishing LTD:, Oxford, UK). The genes for membrane glycoprotein (M6a) and chloride channel 3 (CLCN3) were analyzed by direct sequencing for mutations. RESULTS A new locus for arRP (RP29) has been mapped to chromosome 4q32-q34. A maximum two-point LOD score of 3.76 was obtained for the marker D4S415, with no recombination. Two recombination events in the pedigree positioned this locus to a region flanked by markers D4S621 and D4S2417. A putative region of homozygosity by descent was observed between the loci D4S3035 and D4S2417, giving a probable disease interval of 4.6 cM. Mutation screening of two candidate genes, M6a and CLCN3, revealed no disease-associated mutations. CONCLUSIONS The results suggest that the arRP phenotype maps to a new locus and is due to a mutated gene within the 4q32-q34 chromosomal region.
American Society of Echocardiography and Society of Cardiovascular Anesthesiologists Task Force Guidelines for Training in Perioperative Echocardiography

W hen expertly utilized, perioperative echocardiography can lead to improved outcome in patients requiring cardiovascular surgery and in those suffering perioperative cardiovascular instability. However, prior publications have not specified the requisite training for perioperative echocardiography. Therefore, the American Society of Echocardiography (ASE) and the Society of Cardiovascular Anesthesiologists (SCA) appointed a joint task force to delineate guidelines for training in perioperative echocardiography including the prerequisite medical knowledge and training, echocardiographic knowledge and skills, training components and duration, training environment and supervision, and equivalence requirements for postgraduate physicians already in practice. This document is the result of the task force’s deliberations and recommendations. For the purposes of these guidelines, perioperative echocardiography is defined as transesophageal echocardiography (TEE), epicardial echocardiography, or epiaortic ultrasonography performed in surgical patients immediately before, during, or after surgery. Although transthoracic echocardiography may be indicated and is often performed before and after surgery, it is rarely performed during surgery. Thus, these guidelines do not apply to perioperative transthoracic echocardiography, nor do they apply to TEE performed in nonsurgical patients.
Concordance between Parent Inventory and Directly Observed Measures of Attachment.

This study was a further development of a parent inventory measure of attachment for young children. Observed child reunion behaviors, based on prior research, were transformed into a twenty item parent inventory format Maternal inventory responses for 233 low income, five year old children were factor analyzed and the obtained factors were compared with previous categories based upon direct observation. Factor analysis yielded a six factor solution. Sixteen of the twenty behaviors could be classified into previously established categories of attachment. The advantages of the use of the measure in naturalistic settings, for large sample and multiple attachment figure comparisons, and reduced data collection time were discussed. ∗This research was supported, in part, by a grant from the Administration for Children, Youth and Families, Head Start, 98600.91‐3 to the Head Start School Transition Demonstration Evaluation Project.
The issue network: reshaping the stakeholder model

Who is a stakeholder? In this paper, stakeholders are defined in terms of who has a stake in an issue instead of who has a stake in a firm, and in so doing introduces the idea of an “issue network. ” Drawing on concepts familiar to the social movements (sociology) and interest groups (political science) literatures, I argue that members of an issue network can be identified as those with grievances, resources, or opportunities. To illustrate this argument, I consider the issue of land use in the western United States, showing how various environmental organizations might fit into such a land use network. I conclude with the INSPIRE model, which locates my argument in this larger model of stakeholder management currently being constructed in the stakeholder literature. Copyright © 2010 ASAC. Published by John Wiley & Sons, Ltd.
Extending Hall's Theorem into List Colorings: A Partial History

In 1988, A. J. W. Hilton and P. D. Johnson Jr. found a natural generalization of the condition in Philip Hall's celebrated theorem on systems of distinct representatives. This generalization was formed in the relatively new theory of list colorings of graphs. Here we give an account of a strand of development arising from this generalization, concentrating on extensions of Hall's theorem. New results are presented concerning list colorings of independence systems and colorings of graphs with nonnegative measurable functions on positive measure spaces.
Dynamics of Synoptic Eddy and Low-Frequency Flow Interaction. Part III: Baroclinic Model Results

Abstract In this three-part study, a linear closure has been developed for the synoptic eddy and low-frequency flow (SELF) interaction and demonstrated that internal dynamics plays an important role in generating the leading low-frequency modes in the extratropical circulation anomalies during cold seasons. In Part III, a new linearized primitive equation system is first derived for time-mean flow anomalies. The dynamical operator of the system includes a traditional part depending on the observed climatological mean state and an additional part from the SELF feedback closure utilizing the observed climatological properties of synoptic eddy activity. The latter part relates nonlocally all the anomalous eddy-forcing terms in equations of momentum, temperature, and surface pressure to the time-mean flow anomalies. Using the observational data, the closure was validated with reasonable success, and it was found that terms of the SELF feedback in the momentum and pressure equations tend to reinforce the low-f.
Regulatory ATPase Sites of Cytoplasmic Dynein Affect Processivity and Force Generation*S⃞

The heavy chain of cytoplasmic dynein contains four nucleotide-binding domains referred to as AAA1–AAA4, with the first domain (AAA1) being the main ATP hydrolytic site. Although previous studies have proposed regulatory roles for AAA3 and AAA4, the role of ATP hydrolysis at these sites remains elusive. Here, we have analyzed the single molecule motility properties of yeast cytoplasmic dynein mutants bearing mutations that prevent ATP hydrolysis at AAA3 or AAA4. Both mutants remain processive, but the AAA4 mutant exhibits a surprising increase in processivity due to its tighter affinity for microtubules. In addition to changes in motility characteristics, AAA3 and AAA4 mutants produce less maximal force than wild-type dynein. These results indicate that the nucleotide binding state at AAA3 and AAA4 can allosterically modulate microtubule binding affinity and affect dynein processivity and force production.
The conscientious HR manager and the Rubik's Cube

Purpose – By examining the literature on the ethical dilemmas of H/RM practitioners, the paper aims to put an “H” in H/RM.Design/methodology/approach – Analysing the significant contribution which H/RM scholars have made in studying the ethical dilemmas of H/RM practitioners, the paper builds a view of an H/RM practitioner as a “conscientious HR manager” loosely connected to an ethical dilemma, a “Rubik's Cube”. Using these linguistic devices to simplify others scholarly work, the paper introduces a complex autopoietic system to provide a more “connected knowing” of ethical dilemmas and the “H” in H/RM.Findings – Generalising from this analysis, the paper connects a social sub‐system (H/RM) with a living human system.Research limitations/implications – Naturalistic “grounds” for launching a normative critique of H/RM that celebrates humans as social and biological animals are provisionally outlined.Originality/value – The paper adapts Capra's complex autopoietic system to present a normative critique of H.
L'efficience des stratégies de réhabilitation

Cette presentation vous renseignera sur les modeles de rehabilitation psychosociale destines aux personnes souffrant de troubles psychiatriques durables et sur les traitements les plus efficaces, appuyes par des resultats probants. Les modeles Vulnerabilite-Stress-Competence et le modele de retablissement seront discutes. Par la suite, les strategies dont l’efficience a ete verifiee par des etudes seront presentees, en mettant l’accent sur leurs benefices identifies, leurs limites et leur contribution afin d’eviter les rechutes et de favoriser le retablissement des personnes. Il sera entre autre question des strategies suivantes : 1) approches centrees sur l’acquisition d’habiletes (skills training) ; 2) le suivi intensif (Modele ACT) ; 3) les programmes de soutien a l’emploi, (Vocational rehabilitation) ; 4) l’approche integree aupres des personnes souffrant de troubles concomitants ; 5) les approches visant la remediation cognitive ; 6) les approches aupres des familles ; 7) la TCC (therapie cognitive comportementale) visant la reduction des symptomes psychotiques et de la detresse.
Stimulation of fibronectin production by retinoic acid in mouse skin tumors.

Skin tumors were induced on the backs of Swiss white mice by application of a tumor initiator, dimethylbenz( a )anthracene, followed by chronic application of a tumor promoter, 12- O -tetradecanoylphorbol-13-acetate. Some mice received vehicle (acetone) 1 hr before each 12- O -tetradecanoylphorbol-13-acetate application, others received retinoic acid before each 12- O -tetradecanoylphorbol-13-acetate treatment (chronic retinoic acid treatment), and the remaining mice received four applications of retinoic acid at 12-hr intervals in the 48 hr before the final 12- O -tetradecanoylphorbol-13-acetate application (acute retinoic acid treatment). Mice promoted for 10 weeks formed papillomas. Control mice promoted for 22 weeks had carcinomas, while the chronic retinoic acid-treated mice formed papillomas. The tumors were excised and incubated in medium, and the tumors and media were radioactively labeled, either chemically by iodination or metabolically by incubation in [35S]methionine. The media were collected and the tumors were extracted with urea to give cell-associated material. Sodium dodecyl sulfate-polyacrylamide gel electrophoresis revealed that the media and cell-associated fraction of the retinoic acid-treated mice contained more of a high-molecular-weight protein ( M r >400,000) than did the control tumors. We subjected the media and cell-associated protein to affinity chromatography on gelatin attached to Sepharose 4B. The chronic retinoic acid-treated tumors contained the most gelatin-binding protein, the control tumors the least, and the acutely retinoic acid-treated tumor an intermediate amount. Carcinomas contained less gelatin-binding protein than did papillomas. The protein retained on the gelatin column showed behavior on sodium dodecyl sulfate-polyacrylamide gel electrophoresis similar to that of authentic mouse fibronectin. Papillomas were induced in another group of mice, by the two-step regimen described above. One half of the group received vehicle (acetone) before each of the 12- O -tetradecanoylphorbol-13-acetate applications during the 16-week promotion regimen, while the other half received a topical application of retinoic acid. The tumors were excised and incubated either in [3H]leucine or [3H]fucose for 4 hr, the media were collected, and the tumors were extracted with urea and deoxycholate to extract fibronectin. The media and cell-associated proteins were analyzed by gelatin affinity chromatography and by immunoprecipitation with anti-mouse fibronectin antibody. The media and tumor extracts of the retinoic acid-treated mice contained approximately 2 times as much fibronectin as did the control tumors. Sodium dodecyl sulfate-polyacrylamide gel electrophoresis of the immunoprecipitated protein and the protein isolated by gelatin affinity chromatography gave protein bands characteristic of fibronectin. We conclude that, in vivo , retinoic acid, which inhibits tumor induction at the promotion step, stimulates the production of a high-molecular-weight glycoprotein identified as fibronectin.
Kernelized Online Imbalanced Learning with Fixed Budgets

Online learning from imbalanced streaming data to capture the nonlinearity and heterogeneity of the data is significant in machine learning and data mining. To tackle this problem, we propose a kernelized online imbalanced learning (KOIL) algorithm to directly maximize the area under the ROC curve (AUC). We address two more challenges: 1) How to control the number of support vectors without sacrificing model performance; and 2) how to restrict the fluctuation of the learned decision function to attain smooth updating. To this end, we introduce two buffers with fixed budgets (buffer sizes) for positive class and negative class, respectively, to store the learned support vectors, which can allow us to capture the global information of the decision boundary. When determining the weight of a new support vector, we confine its influence only to its $k$-nearest opposite support vectors. This can restrict the effect of new instances and prevent the harm of outliers. More importantly, we design a sophisticated scheme to compensate the model after replacement is conducted when either buffer is full. With this compensation, the learned model approaches the one learned with infinite budgets. We present both theoretical analysis and extensive experimental comparison to demonstrate the effectiveness of our proposed KOIL.
2-Iodo-6-methoxy-4-nitroaniline: tripartite ribbons built from N-H...O hydrogen bonds and iodo-nitro interactions are pi-stacked into sheets.

Molecules of the title compound, C7H7IN2O3, are linked by pairs of N-H.O hydrogen bonds into C(8)C(8)[R(2)(2)(6)] chains of rings, and antiparallel pairs of such chains are linked by a two-centre iodo-nitro interaction into tripartite ribbons. A single aromatic pi-pi stacking interaction links the ribbons into sheets.
Active Defense Model of Wireless Sensor Networks Based on Evolutionary Game Theory

Wireless sensor networks have great potential to be employed in various real time fields, such as, military, industry and traffic surveillance, etc. However, due to power and memory limitations of sensor nodes, one of the major challenges about wireless sensor networks is security. Based on evolutionary game theory, the paper proposes an active defense model for wireless sensor networks where nodes have limited rationality of evolutionary learning ability. The nodes can be active and dynamic to adjust their defensive strategies so as to achieve the most effective defense, according to the attacker's different policies. The results of the simulation verify the correctness of our theoretical analysis and the feasibility and effectiveness of our model.
Enhancing Semantic Expressivity in the Cultural Heritage Domain

Describing cultural heritage objects from the perspective of Linked Open Data (LOD) is not a trivial task. The process often requires not only choosing pertinent ontologies but also developing new models that preserve the most information and express the semantic power of cultural heritage data. Indeed, data managed in archives, libraries, and museums are complex objects themselves, which require a deep reflection on even nonconventional conceptual models. Starting from these considerations, this article describes a research project: to expose the vastness of one of the most important collections of European cultural heritage, the Zeri Photo Archive, as LOD. We describe here the steps we undertook to this end. First, we developed two ad hoc ontologies for describing all issues not completely covered by existent models (the F Entry and the OA Entry Ontology). Then we mapped into RDF the descriptive elements used in the current Zeri Photo Archive catalog, converting into CIDOC CRM and into the two new aforementioned models the source data based on the Italian content standards Scheda F (photography entry, in English) and Scheda OA (work of art entry, in English). Finally, we created an RDF dataset of the output of the mapping that could show a result capable of demonstrating the complexity of our scenario.
Autophagic clearance of bacterial pathogens: molecular recognition of intracellular microorganisms

Autophagy is involved in several physiological and pathological processes. One of the key roles of the autophagic pathway is to participate in the first line of defense against the invasion of pathogens, as part of the innate immune response. Targeting of intracellular bacteria by the autophagic machinery, either in the cytoplasm or within vacuolar compartments, helps to control bacterial proliferation in the host cell, controlling also the spreading of the infection. In this review we will describe the means used by diverse bacterial pathogens to survive intracellularly and how they are recognized by the autophagic molecular machinery, as well as the mechanisms used to avoid autophagic clearance.
A learning method for recurrent networks based on minimization of finite automata

A novel network model and a learning algorithm based on symbol processing theory are described. The algorithm is derived from the minimization method of finite automata under the correspondence between Elman networks and finite automata. An attempt was made to learn context-free grammars by the new model network. Even though this learning method was derived under the correspondence to finite automata, the network can learn the subgrammar, which is the important feature for distinguishing context-free grammars and finite state automata. <<ETX>>
Contrasting effects of heterozygosity on survival and hookworm resistance in California sea lion pups

Low genetic heterozygosity is associated with loss of fitness in many natural populations. However, it remains unclear whether the mechanism is related to general (i.e. inbreeding) or local effects, in particular from a subset of loci lying close to genes under balancing selection. Here we analyse involving heterozygosity–fitness correlations on neonatal survival of California sea lions and on susceptibility to hookworm (Uncinaria spp.) infection, the single most important cause of pup mortality. We show that regardless of differences in hookworm burden, homozygosity is a key predictor of hookworm‐related lesions, with no single locus contributing disproportionately. Conversely, the subsequent occurrence of anaemia due to blood loss in infected pups is overwhelmingly associated with homozygosity at one particular locus, all other loci showing no pattern. Our results suggest contrasting genetic mechanisms underlying two pathologies related to the same pathogen. First, relatively inbred pups are less able to expel hookworms and prevent their attachment to the intestinal mucosa, possibly due to a weakened immune response. In contrast, infected pups that are homozygous for a gene near to microsatellite Hg4.2 are strongly predisposed to anaemia. As yet, this gene is unknown, but could plausibly be involved in the blood‐coagulation cascade. Taken together, these results suggest that pathogenic burden alone may not be the main factor regulating pathogen‐related mortality in natural populations. Our study could have important implications for the conservation of small, isolated or threatened populations, particularly when they are at a risk of facing pathogenic challenges.