Miracle-dz/UniFAR-FTUs huggingface dataset:
From exclusion to discrimination: Gender inequality in the senior management of Nigerian universities

The study examined factors encouraging gender inequality in university management in three selected universities in Southwestern Nigeria. This was with a view to assessing women's participation in the senior management positions in the region. Data were obtained from primary and secondary sources. A questionnaire was administered to senior academic and non academic staff in Adekunle Ajasin University, Akungba-Akoko; Obafemi Awolowo University, Ile-Ife; and Redeemer's University, Mowe. Out of the 222 copies of the questionnaire administered, 192 copies (86.5%) were retrieved. Interviews were also conducted with the most senior staff in the selected universities to elicit information on senior management positions held by women compared to men. The data were analysed using inferential statistics and content analysis. The results showed that there was low representation of women (29.2%) compared to men (70.8%) in senior management positions in the selected universities. This was attributed to inadequate numbers of qualified women (42.6%), patriarchy (14.9%), domestic and family demands (10.6%), socio-cultural beliefs that leadership is the prerogative of men (9.6%), lack of encouragement and support (8.5%), lack of leadership skills (7.5%) and poor mentorship (2.1%), among other factors. Policy implications of the study are discussed.
A pr il 20 08 Evidence-Based Psychosocial Treatments for Phobic and Anxiety Disorders in Children and Adolescents

Journal of Clinical Child & Adolescent Psychology Publication details, including instructions for authors and subscription information: http://www.informaworld. com/smpp/title~content=t775648094 Evidence-Based Psychosocial Treatments for Phobic and Anxiety Disorders in Children and Adolescents Wendy K. Silverman a; Armando A. Pina b; Chockalingam Viswesvaran a a Florida International University, b Arizona State University,
Robin Sequence: From Diagnosis to Development of an Effective Management Plan

The triad of micrognathia, glossoptosis, and resultant airway obstruction is known as Robin sequence (RS). Although RS is a well-recognized clinical entity, there is wide variability in the diagnosis and care of children born with RS. Systematic evaluations of treatments and clinical outcomes for children with RS are lacking despite the advances in clinical care over the past 20 years. We explore the pathogenesis, developmental and genetic models, morphology, and syndromes and malformations associated with RS. Current classification systems for RS do not account for the heterogeneity among infants with RS, and they do not allow for prediction of the optimal management course for an individual child. Although upper airway obstruction for some infants with RS can be treated adequately with positioning, other children may require a tracheostomy. Care must be customized for each patient with RS, and health care providers must understand the anatomy and mechanism of airway obstruction to develop an individualized treatment plan to improve breathing and achieve optimal growth and development. In this article we provide a comprehensive overview of evaluation strategies and therapeutic options for children born with RS. We also propose a conceptual treatment protocol to guide the provider who is caring for a child with RS.
Estimation of melting points of pyridinium bromide ionic liquids with decision trees and neural networks

Regression trees were built with an initial pool of 1085 molecular descriptors calculated by DRAGON software for 126 pyridinium bromides, to predict the melting point. A single tree was derived with 9 nodes distributed over 5 levels in less than 2 min showing very good correlation between the estimated and experimental values (R2 = 0.933, RMS = 12.61 °C). A number n of new trees were grown sequentially, without the descriptors selected by previous trees, and combination of predictions from the n trees (ensemble of trees) resulted in higher accuracy. A 3-fold cross-validation with the optimum number of trees (n = 4) yielded an R2 value of 0.822. A counterpropagation neural network was trained with the variables selected by the first tree, and reasonable results were achieved (R2 = 0.748). In a test set of 9 new pyridinium bromides, all the low melting point cases were successfully identified.
Desenvolvimento de competências gerenciais na enfermagem: experiência entre residentes

Objetivo : Relatar a experiencia do processo de ensino-aprendizagem com foco no desenvolvimento de competencias gerenciais entre residentes de enfermagem. Metodo : estudo do tipo relato de experiencia, ocorrido nos meses de maio e junho de 2015. Foi realizado no Programa de Residencia em Gerenciamento de Enfermagem em Clinica Medica e Cirurgica da Universidade Estadual do Oeste do Parana, a partir da organizacao do processo de ensino-aprendizagem, incutido a disciplina de Gerenciamento dos Servicos de Enfermagem II, onde se realizou Seminarios Integrados dos conteudos voltados ao desenvolvimento da gestao pautada em competencias, utilizando-se discussao de material teorico e relato de situacao problema. Resultados : Os resultados compreendem as competencias gerenciais trabalhadas nos seminarios, sendo elas: processo decisorio, lideranca, comunicacao e administracao e gerenciamento. O desenvolvimento desse tipo de metodo educacional proporcionou o resgate de conceitos teoricos e discussoes sobre a pratica gerencial com base na literatura atual. Conclusao : As competencias gerenciais devem receber atencao especial nos curriculos de enfermagem, principalmente quando somadas a metodos alternativos que proporcionem criticidade no processo ensino-aprendizagem.
Gld2-catalyzed 3′ monoadenylation of miRNAs in the hippocampus has no detectable effect on their stability or on animal behavior

Gld2, a noncanonical cytoplasmic poly(A) polymerase, interacts with the RNA binding protein CPEB1 to mediate polyadenylation-induced translation in dendrites of cultured hippocampal neurons. Depletion of Gld2 from the hippocampus leads to a deficit in long-term potentiation evoked by theta burst stimulation. At least in mouse liver and human primary fibroblasts, Gld2 also 3′ monoadenylates and thereby stabilizes specific miRNAs, which enhance mRNA translational silencing and eventual destruction. These results suggest that Gld2 would be likely to monoadenylate and stabilize miRNAs in the hippocampus, which would produce measurable changes in animal behavior. We now report that using Gld2 knockout mice, there are detectable alterations in specific miRNA monoadenylation in the hippocampus when compared to wild type, but that these modifications produce no detectable effect on miRNA stability. Moreover, we surprisingly find no overt change in animal behavior when comparing Gld2 knockout to wild-type mice. These data indicate that miRNA monoadenylation-mediated stability is cell type-specific and that monoadenylation has no measurable effect on higher cognitive function.
The p75 receptor transduces the signal from myelin-associated glycoprotein to Rho

Myelin-associated glycoprotein (MAG) is a potent inhibitor of neurite outgrowth from a variety of neurons. The receptor for MAG or signals that elicit morphological changes in neurons remained to be established. Here we show that the neurotrophin receptor p75 (p75NTR) is the signal transducing element for MAG. Adult dorsal root ganglion neurons or postnatal cerebellar neurons from mice carrying a mutation in the p75NTR gene are insensitive to MAG with regard to neurite outgrowth. MAG activates small GTPase RhoA, leading to retarded outgrowth when p75NTR is present. Colocalization of p75NTR and MAG binding is seen in neurons. Ganglioside GT1b, which is one of the binding partners of MAG, specifically associates with p75NTR. Thus, p75NTR and GT1b may form a receptor complex for MAG to transmit the inhibitory signals in neurons.
The IRAS 1.2 Jy Survey: Redshift Data

We present the redshift data for a survey of galaxies selected from the data base of the Infrared Astronomical Satellite (IRAS). This survey extends the 1.936 Jy sample of Strauss et al. (1992a) from a (cid:13)ux limit of 1.936 Jy at 60(cid:22)m to 1.2 Jy. The survey extension consists of 3920 sources in the (cid:13)ux interval 1.2 { 1.936 Jy, of which 2663 are galaxies with measured redshifts. Fourteen objects (0.52%) do not have redshifts. The survey covers 87.6% of the sky. The data for the complete 1.2 Jy survey (the data presented here in addition to that of Strauss et al. 1992a) may be obtained in a machine-readable form from the National Space Science Data Center.
Evidence That Collapsin Response Mediator Protein-2 Is Involved in the Dynamics of Microtubules*

Collapsin response mediator protein-2 (CRMP-2) is a member of the CRMP/TOAD/Ulip/DRP family of cytosolic phosphoproteins involved in neuronal differentiation and axonal guidance. CRMP-2 mediates the intracellular response to collapsin 1/semaphorin 3A, a repulsive extracellular guidance cue for axonal outgrowth. The mutation of UNC-33, a Caenorhabditis elegans homolog of CRMP-2, results in abnormality of microtubules in neurites, but the mechanism of CRMP-2 action remains to be clarified. Here, we report that overexpression of human CRMP-2 in Neuro2a cells, a mouse neuroblastoma cell line, results in blebbing of the cytoplasm. Furthermore, some cells exhibited intranuclear inclusions, which were labeled with antibodies to CRMP-2 and tubulin. CRMP-2 was found to be associated with microtubule bundles in the spindles at the metaphase and in the midbodies at the late telophase in mitotic cells. Thus, it is most likely that failure of complete disassembly of the spindle microtubules during mitosis is responsible for the formation of these intranuclear inclusions. We suggest that CRMP-2 functions by regulating the dynamics of microtubules.
A Comparison of the Nutritional Value, Sensory Qualities, and Food Safety of Organically and Conventionally Produced Foods

Referee: Dr. William Lockeretz, Professor, School of Nutrition Science and Policy, Tufts University, Medford, MA 12155 Given the significant increase in consumer interest in organic food products, there is a need to determine to what extent there is a scientific basis for claims made for organic produce. Studies comparing foods derived from organic and conventional growing systems were assessed for three key areas: nutritional value, sensory quality, and food safety. It is evident from this assessment that there are few well-controlled studies that are capable of making a valid comparison. With the possible exception of nitrate content, there is no strong evidence that organic and conventional foods differ in concentrations of various nutrients. Considerations of the impact of organic growing systems on nutrient bioavailability and nonnutrient components have received little attention and are important directions for future research. While there are reports indicating that organic and conventional fruits and vegetables may differ on a variety of sensory qualities, the findings are inconsistent. In future studies, the possibility that typical organic distribution or harvesting systems may deliver products differing in freshness or maturity should be evaluated. There is no evidence that organic foods may be more susceptible to microbiological contamination than conventional foods. While it is likely that organically grown foods are lower in pesticide residues, there has been very little documentation of residue levels.
Connecting Cortical and Behavioral Dynamics: Bimanual Coordination

For the paradigmatic case of bimanual coordination, we review levels of organization of behavioral dynamics and present a description in terms of modes of behavior. We briefly review a recently developed model of spatiotemporal brain activity that is based on short-and long-range connectivity of neural ensembles. This model is specified for the case of motor and sensorimotor units embedded in the neural sheet. Focusing on the cortical left-right symmetry, we derive a bimodal description of the brain activity that is connected to behavioral dynamics. We make predictions of global features of brain dynamics during coordination tasks and test these against experimental magnetoencephalogram (MEG) results. A key feature of our approach is that phenomenological laws at the behavioral level can be connected to a field-theoretical description of cortical dynamics.
Alcohol and memory: amnesia and short-term memory function during experimentally induced intoxication.

This study represents the first attempt to examine the alcoholic blackout during a sustained period of experimental intoxication. Thirteen male alcoholics with histories of blackouts drank large amounts of beverage alcohol for 12 to 14 days. Daily assessments of short-term memory and 24-hour recall were made. Short-term memory was significantly and progressively impaired with increasing levels of intoxication. Impairment of 24-hour recall was also related to level of intoxication on the preceding day. Blackouts occurred, particularly among subjects with impaired short-term memory function. Conversely, subjects with intact short-term memory had normal 24-hour recall.
Metastatic pattern of uterine leiomyosarcoma: retrospective analysis of the predictors and outcome in 113 patients

Objective To describe metastatic pattern of uterine leiomyosarcomas (ULMS) and correlate it with clinical and histopathologic parameters. Methods We included 113 women (mean age, 53 years; range, 29 to 72 years) with histopathology-confirmed ULMS from 2000 to 2012. Distribution of metastases was noted from imaging by two radiologists in consensus. Predictors of development of metastases were analyzed with univariate and multivariate analysis. Impact of various clinical and histopathologic parameters on survival was compared using Log-rank test and Cox proportional hazard regression model. Results Distant metastases were seen in 81.4% (92/113) of the patients after median interval of 7 months (interquartile range, 1 to 21). Lung was most common site of metastases (74%) followed by peritoneum (41%), bones (33%), and liver (27%). Local tumor recurrence was noted in 57 patients (50%), 51 of whom had distant metastases. Statistically significant correlation was noted between local recurrence and peritoneal metastases (p<0.001) and between lung and other common sites of hematogeneous metastases (p<0.05). Age, serosal involvement, local recurrence, and the International Federation of Gynecology and Obstetrics (FIGO) stage were predictive factors for metastases. At the time of reporting, 65% (74/113) of the patients have died; median survival was 45 months. Stage, local recurrence, and age were poor prognostic factors. Conclusion ULMS metastasizes most frequently to lung, peritoneum, bone, and liver. Local recurrence was associated with peritoneal spread and lung metastases with other sites of hematogeneous metastases. Age, FIGO stage and local recurrence predicted metastatic disease and advanced stage, older age and local recurrence predicted poor outcome.
Consumer Scapegoating in the 2008 Chinese Milk Contamination Crisis Title of Paper

When a multi-brand product-harm crisis occurs, consumers seek vengeance for betrayal of their trust. They often find a scapegoat to transfer blame and discharge tensions arising. Drawing on attribution theory and the psychology of tension discharge, we examine scapegoat effects in the 2008 Chinese milk contamination crisis. The central thesis of the conceptual model of scapegoating in this study is that consumers tend to transfer blame and discharge their frustration and anger through finding an easy scapegoat target. Quantitative evidence is found that the first brand caught out becomes a scapegoat, taking disproportionate blame for other contaminated brands and for other parties involved in this industry-wide crisis.
Intestinal Neuronal Dysplasia-Like Submucosal Ganglion Cell Hyperplasia at the Proximal Margins of Hirschsprung Disease Resections

Intestinal neuronal dysplasia type B (IND) denotes an increased proportion of hyperplastic submucosal ganglia, as resolved histochemically in 15-μm-thick frozen sections. IND has been reported proximal to the aganglionic segment in patients with Hirschsprung disease (HSCR) and is putatively associated with a higher rate of postsurgical dysmotility. We developed and validated histological criteria to diagnose IND-like submucosal ganglion cell hyperplasia (IND-SH) in paraffin sections and used the approach to study the incidence and clinical and/or genetic associations of IND-SH at the proximal margins of HSCR pull-through resection specimens. Full-circumference paraffin sections from the proximal margins of 64 HSCR colonic pull-through specimens and 24 autopsy controls were immunostained for neuron-specific Hu antigen, and nucleated ganglion cells in each submucosal ganglion were counted. In controls, an age-related decline in the relative abundance of “giant” ganglia (≥7 nucleated Hu-positive [Hu+] ganglion cells) was observed. A conservative diagnostic threshold for IND-SH (control mean ± 3× standard deviation) was derived from 15 controls less than 25 weeks of age. No control exceeded this threshold, whereas in the same age range, IND-SH was observed at the proximal margins in 15% (7 of 46) of HSCR resections, up to 15 cm proximal to the aganglionic segment. No significant correlation was observed between IND-SH and length of or distance from the aganglionic segment, sex, trisomy 21, RET or SEMA3C/D polymorphisms, or clinical outcome, but analysis of more patients, with better long-term follow-up will be required to clarify the significance of this histological phenotype.
Neuroglobin and cytoglobin: oxygen-binding proteins in retinal neurons.

PURPOSE The goal of this study was to describe the detailed localization of the novel oxygen-binding molecules, neuroglobin (Ngb) and cytoglobin (Cygb), in mammalian retinas and to determine whether Ngb and Cygb are neuronal or glial proteins in the retina. METHODS Antibodies directed against Ngb and Cygb were used to examine their patterns of distribution in normal canine retinas. Immunoblot analysis was performed to verify antibody specificity and the presence of Ngb and Cygb in canine tissues. Double-labeling immunohistochemistry was performed with the Ngb and Cygb antibodies along with antibodies against neuronal (MAP-2, class III beta-tubulin (TUJ1), PKCalpha, and calretinin) and glial antigens (vimentin and CRALBP). Tissue sections were analyzed with light and confocal microscopy. RESULTS Ngb and Cygb proteins were observed in different retinal cells. Cygb (but not Ngb) was also present in canine kidney, liver, lung, and heart tissue. Immunohistochemical analysis of canine retinas demonstrated Ngb immunoreactivity (IR) in the ganglion cell layer (GCL), inner (INL) and outer (ONL) nuclear layers, inner (IPL) and outer plexiform (OPL) layers, photoreceptor inner segments (IS), and retinal pigment epithelium (RPE). Ngb IR was localized within retinal neurons, but not in glia. Cygb IR was found in neurons and their processes in the GCL, IPL, INL, and OPL and within the RPE, but not in glia. CONCLUSIONS Ngb and Cygb are widely distributed in retinal neurons and RPE, but not in glial cells of the canine retina. Their structure and distribution is suggestive of a possible role in oxygen transport in the mammalian retina.
A BCI using VEP for continuous control of a mobile robot

A brain-computer interface (BCI) translates brain activity into commands to control devices or software. Common approaches are based on visual evoked potentials (VEP), extracted from the electroencephalogram (EEG) during visual stimulation. High information transfer rates (ITR) can be achieved using (i) steady-state VEP (SSVEP) or (ii) code-modulated VEP (c-VEP). This study investigates how applicable such systems are for continuous control of robotic devices and which method performs best. Eleven healthy subjects steered a robot along a track using four BCI controls on a computer screen in combination with feedback video of the movement. The average time to complete the tasks was (i) 573.43 s and (ii) 222.57 s. In a second non-continuous trial-based validation run the maximum achievable online classification accuracy over all subjects was (i) 91.36 % and (ii) 98.18 %. This results show that the c-VEP fits the needs of a continuous system better than the SSVEP implementation.
A Study on Relationship between Emotional Intelligence and Employee Performance in Indian IT Sector

Emotional intelligence is a relatively recent behavioral model gaining prominence with Daniel Goleman's 1995 book called 'Emotional Intelligence'. It is the ability to acquire and apply the knowledge from emotions of self and others. Indian IT industry is one of the highest contributors to Indian economy and is on its path of continued growth momentum. This study has investigated the relationship between emotional intelligence and the employee performance in Indian IT sector and demographic factors influencing emotional intelligence of IT employees. Data for the study were collected from 400 IT employees of select IT companies in Hyderabad using three questionnaires namely Emotional Intelligence with its four domains i.e. Self Emotion Appraisal (SEA), Others' Emotion Appraisal (OEA), Use of Emotion (UOE) and Regulation of Emotion (ROE) were set as independent variables while task performance is defined as dependent variable. Gender, age level, education and experience were selected as demographic variables of the study. Through careful analysis of data, a positive correlation was found between emotional intelligence domains (SEA, OEA, UOE and ROE) and the employee performance and it was concluded that emotional intelligence and performance of Indian IT employees are positively correlated. Significant relationships were established between all demographic factors of the study and emotional intelligence of employees. The conclusion was that the demographic factors of IT employees have significant contribution to emotional intelligence of employees.
Bevacizumab plus irinotecan in recurrent glioblastoma multiforme.

PURPOSE The prognosis for patients with recurrent glioblastoma multiforme is poor, with a median survival of 3 to 6 months. We performed a phase II trial of bevacizumab, a monoclonal antibody to vascular endothelial growth factor, in combination with irinotecan. PATIENTS AND METHODS This phase II trial included two cohorts of patients. The initial cohort, comprising 23 patients, received bevacizumab at 10 mg/kg plus irinotecan every 2 weeks. The dose of irinotecan was based on the patient's anticonvulsant: Patients taking enzyme-inducing antiepileptic drugs (EIAEDs) received 340 mg/m2, and patients not taking EIAEDs received 125 mg/m2. After this regimen was deemed safe and effective, the irinotecan schedule was changed to an accepted brain tumor regimen of four doses in 6 weeks, in anticipation of a phase III randomized trial of irinotecan versus irinotecan and bevacizumab. The second cohort, comprising 12 patients, received bevacizumab 15 mg/kg every 21 days and irinotecan on days 1, 8, 22, and 29. Each cycle was 6 weeks long and concluded with patient evaluations, including magnetic resonance imaging. RESULTS The 6-month progression-free survival among all 35 patients was 46% (95% CI, 32% to 66%). The 6-month overall survival was 77% (95% CI, 64% to 92%). Twenty of the 35 patients (57%; 95% CI, 39% to 74%) had at least a partial response. One patient developed a CNS hemorrhage, which occurred in his 10th cycle. Four patients developed thromboembolic complications (deep venous thrombosis and/or pulmonary emboli). CONCLUSION Bevacizumab and irinotecan is an effective treatment for recurrent glioblastoma multiforme and has moderate toxicity.