Miracle-dz/UniFAR-FTUs huggingface dataset:
Topic Modeling of Multimodal Data: An Autoregressive Approach

Topic modeling based on latent Dirichlet allocation (LDA) has been a framework of choice to deal with multimodal data, such as in image annotation tasks. Recently, a new type of topic model called the Document Neural Autoregressive Distribution Estimator (DocNADE) was proposed and demonstrated state-of-the-art performance for text document modeling. In this work, we show how to successfully apply and extend this model to multimodal data, such as simultaneous image classification and annotation. Specifically, we propose SupDocNADE, a supervised extension of DocNADE, that increases the discriminative power of the hidden topic features by incorporating label information into the training objective of the model and show how to employ SupDocNADE to learn a joint representation from image visual words, annotation words and class label information. We also describe how to leverage information about the spatial position of the visual words for SupDocNADE to achieve better performance in a simple, yet effective manner. We test our model on the LabelMe and UIUC-Sports datasets and show that it compares favorably to other topic models such as the supervised variant of LDA and a Spatial Matching Pyramid (SPM) approach.
Hadoop's Overload Tolerant Design Exacerbates Failure Detection and Recovery

Data processing frameworks like Hadoop need to efficiently address failures, which are common occurrences in today’s large-scale data center environments. Failures have a detr imental effect on the interactions between the framework’s processes. Unfortunately, certain adverse but temporary conditions such as network or machine overload can have a similar effect. Treating this effect oblivious to the real unde rlying cause can lead to sluggish response to failures. We show that this is the case with Hadoop, which couples failure detection and recovery with overload handling into a conservative design with conservative parameter choices. As a result, Hadoop is oftentimes slow in reacting to failures and also exhibits large variations in response time under failu re. These findings point to opportunities for future research on cross-layer data processing framework design.
Data Mining Based Intrusion Detection System in VPN Application

In order to solve the problem that the technology can not satisfy VPN consumer's need about information insurance for the safety resolving tradition's, in the main body of this essay, we have being aimed at it's safe hidden trouble on the basis going deep into the operating principle studying VPN's, have brought forward one kind of scheme, this scheme passes an introduction invade check system, excavate an introduction at the same time with the data arriving at invade have adopted to come to come true owing to that association regulation data excavates an algorithm in detecting system. Indicate result, compete with original network in relatively, this scheme has improved 60% to customer's assurance coefficient. Be one kind of reliable protection measure, fall off or eliminate from the loss that network attack brings about, problem can not solve by the mechanism having resolved tradition protection.
Powers of balancing polynomials and some consequences for Fibonacci sums

In this short article, we derive identities for powers of balancing and Lucas-balancing polynomials. These polynomials are a natural extension of balancing and Lucas-balancing numbers. As an application of the new identities we present closed-forms for sums with certain binomial coefficients involving balancing, Lucas-balancing, Fibonacci and Lucas numbers. Mathematics Subject Classification: 11B39, 11B83, 05A10
Intra-arterial thrombectomy improves functional outcome when administered up to 6 h after stroke

Commentary on: Berkhemer OA, Fransen PS, Beumer D, et al., MR CLEAN Investigators. A randomized trial of intraarterial treatment for acute ischemic stroke. N Engl J Med 2015;372:11–20[OpenUrl][1][CrossRef][2][PubMed][3][Web of Science][4]. Ischaemic stroke is a common cause of death and disability worldwide. Intravenous tissue plasminogen activator (tPA) reduces disability when administered up to 4.5 h after symptom onset. In severe strokes, when a proximal large vessel occlusion is present, recanalisation rates with tPA are low. Intra-arterial (IA) thrombectomy techniques, particularly stent-retriever devices, have much higher recanalisation rates. IA therapy may be used either as an adjunct to tPA in patients presenting within 4.5 h or as monotherapy in patients with an exclusion criteria to tPA. This trial aimed to determine if IA therapy, administered up to 6 h after symptom onset, improved … [1]: {openurl}? query=rft.jtitle%253DN%2BEngl%2BJ%2BMed%26rft.volume%253D372%26rft.spage%253D11%26rft_id%253Dinfo%253Adoi%252F10.1056%252FNEJMoa1411587%26rft_id%253Dinfo%253Apmid%252F25517348%26rft.genre%253Darticle%26rft_val_fmt%253Dinfo%253Aofi%252Ffmt%253Akev%253Amtx%253Ajournal%26ctx_ver%253DZ39.88-2004%26url_ver%253DZ39.88-2004%26url_ctx_fmt%253Dinfo%253Aofi%252Ffmt%253Akev%253Amtx%253Actx [2]: /lookup/external-ref? access_num=10.1056/NEJMoa1411587&link_type=DOI [3]: /lookup/external-ref? access_num=25517348&link_type=MED&atom=%2Febmed%2F20%2F6%2F209.atom [4]: /lookup/external-ref? access_num=000347100800005&link_type=ISI
Lineage commitment in the mammalian preimplantation embryo

Summary Early embryo mortality during the first two weeks of development is an important factor in the decreasing fertility of dairy cattle. During this period the embryo needs to correctly establish the first three lineages, namely epiblast, hypoblast and trophoblast so as to survive. The morphological and molecular events underlying these lineage decisions are discussed, drawing on information derived predominantly from mice and cattle. TE be traced the DiI TE donor cells maintain their original fate and contribute only to TE, they would be considered to have been committed to this fate at the stage that they had been isolated. If they were to contribute to both ICM and TE, they would be considered to have been uncommitted.
Watson: a gateway for next generation semantic web applications

The amount of knowledge published on the Semantic Web – i.e, the number of ontologies and semantic documents available online – is rapidly increasing. Following this evolution, changes appear in the way semantic applications are designed: instead of relying on one, self engineered base of semantic data, these next generation Semantic Web applications [2] assume the existence and availability of a large scale, distributed Web of data. In order for these applications to be able to exploit and combine the increasing amount of semantic data and ontologies available online, a gateway to the Semantic Web is required.
CHEMICAL COMPONENTS AND ANTIBACTERIAL ACTIVITIES OF ESSENTIAL OILS OBTAINED FROM IRANIAN LOCAL LAVANDULA OFFICINALIS AND THYMUS VULGARIS AGAINST PATHOGENIC BACTERIA ISOLATED FROM HUMAN

Essential oils are commonly used to treat minor health problems. In this study the chemical compositions of Lavandula officinalis and Thymus vulgaris were determined by gas chromatography and mass spectrometry. GC/MS analysis of T. vulgaris resulted in thymol as the major oil component where as methyl sulfony exhibited as the most abundant constituent of L. officinalis. The antibacterial activities of these essential oils (Eos) against Five gram negative bacteria, namely Pseudomonas aeruginosa, Salmonella paratyphi (D), Citrobacter, Enterobacter, Escherichia coli and gram positive bacteria Staphylococcus aureus coagulase were investigated. Among the tested plants, Thymus vulgaris showed higher activity against different bacteria, while S.paratyphi and S. aureus were the most resistance bacteria. All the tested plant extracts possessed antimicrobial growth activities with MIC values ranging from 100 to 1509L/mL. The results suggested that due to the potential antimicrobial activities of these essential oils they might be employed in food and pharmaceutical products.
Adaptation model of nearwork‐induced transient myopia

A nearwork model was developed to determine whether variation in accommodative adaptation gain, KA, can account for the differences in the dynamic decay timecourse following near work in hyperopes (HYP), emmetropes (EMM), early‐onset myopes (EOM), and late‐onset myopes (LOM). The model incorporated a proximal component into a previously‐developed adaptation model of accommodation and vergence. It was used to simulate the nearwork‐induced transient myopia (NITM) response following 10 min of congruent binocular near viewing (5 D, 5 MA). The accommodative adaptation gain, KA, value was varied from 1.0 to 6.0 in increments of 0.5. For the hyperopes, an additional constraint was imposed wherein the accommodative response was biased on the under‐accommodated side of the deadspace operator (i.e., depth‐of‐focus). In addition, the effect of prolonged nearwork was simulated by alternating between 1 hr of congruent near viewing (3 D, 3 MA) and 5 min of congruent far viewing (0.25 D, 0.25 MA) over a 160 hr period representing one work‐month with 40 hours of nearwork per week. The steady‐state rms value of the accommodative error was measured as a function of KA. It was found that the NITM timecourses for HYP, EMM, EOM, and LOM could be simulated accurately using KA values of 2.0, 2.5, 4.0 and 5.5, respectively. The long‐term final steady‐state rms of the accommodative error was found to increase from 0.182 D to 0.188 D as KA increased from 1 to 6. This indicated a small and progressive increase in residual accommodative error for higher KA values, which was associated with EOM and LOM. Thus, NITM for the different refractive groups could be quantified by the accommodative adaptation gain element, with KA for the HYP, EMM, and EOM and LOM groups having lower, intermediate, and higher values, respectively. The larger rms for higher KA values suggests that a myopic individual may have a predisposition to exhibit a slightly larger long‐term accommodative error, which may stimulate axial elongation and in turn promote the progression of axial myopia.
Mesh Mould: Differentiation for Enhanced Performance

Mesh-Mould is a novel robotic fabrication system for complex, non-standard concrete structures. The system folds together formwork and reinforcement, the two most labour intensive aspects of concrete constructions and offers an alternative approach to the current modes of prefabrication by suggesting an in-situ fabrication process (Figure 1). The paper outlines the development of the Form-work/Reinforcing Meshes through several iterations of physical and digital tests. Initially starting from simple triangulated 3D lattices, the structures evolved to become more complex and differentiated. The incorporating of flow enhancing ducts and surface perimeters with diverse surface aperture densities facilitates an optimal concrete flow and material distribution within the mesh.
Transient response of integral gain switchover digital control dc-dc converter in discontinuous conduction mode

This paper presents the parameter design of the integral gain switchover function for the digital control dc-dc converter and its transient response in the DCM. The proposed gain switchover function utilizes the load current to determine the integral gain because the output current is detected in the dc-dc converters for the ICT system. The proposed method uses the hysteresis function around the critical current to avoid the gain oscillation. And then, the influence on the transient response by the integral gain of DCM is discussed in this paper. It is verified that the proposed method shows a superior transient response from the CCM to the DCM by switching to select the appropriate integral gain.
Matching law choice analyses of ethanol and sucrose consumption in alcohol-preferring (P), nonpreferring (NP), and Sprague-Dawley (SD) rats.

BACKGROUND Quantitative models of choice, such as the matching law and behavioral economics, allow for the analysis of alcohol consumption within a choice context. Such models can provide further knowledge of phenotypic differences between selected lines of rats. The current study applied the generalized matching law to the ethanol (EtOH) and sucrose consumption of alcohol-preferring (P), nonpreferring (NP), and Sprague-Dawley (SD) rats. METHODS Male P, NP, and SD rats were trained to consume increasing concentrations of EtOH and water in a limited access, 2-bottle choice procedure. The animals were then given concurrent access to pairs of differing EtOH solutions (2, 4, 6, and 10%, v/v) for 1 h/d. A subset of animals from each rat type was subsequently given access to 8% sucrose for 1 h/d for 5 days, and then concurrent access to pairs of differing sucrose solutions (3, 8, and 15%, w/v) for 1 h/d. The generalized matching law was used to assess the relationship between the relative EtOH and sucrose concentrations and the relative volumes of solutions consumed. RESULTS The P rats consumed more EtOH and sucrose than the NP and SD rats overall. However, only the P rats consistently consumed disproportionately greater quantities of the higher EtOH concentration than the lower one, indicating overmatching. Additionally, all 3 types of rats displayed overmatching in the sucrose choice experiment. CONCLUSIONS These data provide further evidence of phenotypic differences between the P rats and other types of rats, and suggest that the generalized matching law can be a useful tool for describing rats' EtOH or sucrose consumption in a 2-bottle choice, limited access paradigm.
In‐stent restenosis of bifurcation lesions: Experience with drug‐eluting balloons

Coronary bifurcation lesions constitute 15–20% of all lesions that require percutaneous coronary intervention. They are at higher risk for clinical and angiographic in-stent restenosis (ISR), greater than 10% in recent registries and observational studies [1,2]. Treatment of bifurcations with any current stent is considered an off-label indication, and dedicated bifurcation stents are currently under clinical investigation [3].
The reasons of dropout of sport in Hong Kong school athletes

Dropout of sport is an issue in sport and public health domains. The aim of this study was to identify the potential dropout reasons of school athletes and to examine if their perception of dropout was affected by the previous dropout experience. There were 50 subjects who were divided into two groups based on their previous dropout experience (Dropout Group=22, No Dropout Group=28). They filled a questionnaire about potential dropout reasons of the current sport. Coach and teammates were two predominated reasons of dropout; Influence of parent and training seemed to affect the termination of the sport to a lesser extent. Moreover, the perception of social value and lost focus were significantly different between two groups. Character of coach and teammates affect the engagement of training in school athletes. However, the parental influence had less influence than expected. Training intensity played little role as the dropout reason. Previous experience of dropout had an impact of potential dropout reasons on their current sport training.
Epidemiologic Determinants Affecting Cigarette Smoking Cessation: A Retrospective Study in a National Health System (SSN) Treatment Service in Rome (Italy)

This retrospective study aims to evaluate epidemiologic characteristics of patients attending stop smoking courses, based on group therapy, testing their influence on smoking cessation in univariate and multivariate model. A total of 123 patients were included in this study. Mean age was 53 (±11). Sixty-seven percent were women. At the end of the courses 66% of patients stopped smoking, after 12 months only 39% remained abstinent. Patients younger than 50 years statistically tended to continue smoking 6 months (P = .02–R.R. = 1.49, C.I. 95%: 1.06–2.44) and 12 months (P = .03–R.R. = 1.37, C.I. 95%: 1.02–2.52) after the end of the courses. A low self-confidence in quitting smoking was significantly related to continuing tobacco consumption after 6 months (P = .016–R.R. = 1.84, C.I. 95%: 1.14–2.99). Low adherence to therapeutic program was statistically associated to maintenance of tobacco use at 6 months (P = .006–R.R. = 1.76, C.I. 95%: 1.32–2.35) and 12 months (P = .050–R.R. = 1.45, C.I. 95%: 1.11–1.88). This association was confirmed at 6 months in the analysis performed on logistic regression model (P = .013).
Revision of AMBER Torsional Parameters for RNA Improves Free Energy Predictions for Tetramer Duplexes with GC and iGiC Base Pairs

All-atom force fields are important for predicting thermodynamic, structural, and dynamic properties of RNA. In this paper, results are reported for thermodynamic integration calculations of free energy differences of duplex formation when CG pairs in the RNA duplexes r(CCGG)2, r(GGCC)2, r(GCGC)2, and r(CGCG)2 are replaced by isocytidine–isoguanosine (iCiG) pairs. Agreement with experiment was improved when ε/ζ, α/γ, β, and χ torsional parameters in the AMBER99 force field were revised on the basis of quantum mechanical calculations. The revised force field, AMBER99TOR, brings free energy difference predictions to within 1.3, 1.4, 2.3, and 2.6 kcal/mol at 300 K, respectively, compared to experimental results for the thermodynamic cycles of CCGG → iCiCiGiG, GGCC → iGiGiCiC, GCGC → iGiCiGiC, and CGCG → iCiGiCiG. In contrast, unmodified AMBER99 predictions for GGCC → iGiGiCiC and GCGC → iGiCiGiC differ from experiment by 11.7 and 12.6 kcal/mol, respectively. In order to test the dynamic stability of the above duplexes with AMBER99TOR, four individual 50 ns molecular dynamics (MD) simulations in explicit solvent were run. All except r(CCGG)2 retained A-form conformation for ≥82% of the time. This is consistent with NMR spectra of r(iGiGiCiC)2, which reveal an A-form conformation. In MD simulations, r(CCGG)2 retained A-form conformation 52% of the time, suggesting that its terminal base pairs may fray. The results indicate that revised backbone parameters improve predictions of RNA properties and that comparisons to measured sequence dependent thermodynamics provide useful benchmarks for testing force fields and computational methods.
Of Myc and Mnt

Deregulation of Myc expression is a common feature in cancer and leads to tumor formation in experimental model systems. There are several potential barriers that Myc must overcome in order to promote tumorigenesis, including its propensity to sensitize many cell types to apoptotic cell death. Myc activities appear also to be constrained and fine-tuned by a set of proteins that include the Mxd (formerly named Mad) family and the related protein Mnt. Like Myc-family proteins, Mxd and Mnt proteins use Max as a cofactor for DNA binding. But Mnt-Max and Mxd-Max complexes are transcriptional repressors and can antagonize the transcriptional activation function of Myc-Max. Studies examining the relationship between Myc, Mxd and Mnt proteins suggest that whereas Mnt plays a general role as a Myc antagonist, Mxd proteins have more specialized roles as Myc antagonist that is probably related to their more restricted expression patterns. The interplay between these proteins is postulated to fine-tune Myc activity for cell-cycle entry and exit, proliferation rate and apoptosis.
Changes in the composition of lung lipids and the "turnover" of dipalmitoyl lecithin in experimental alveolar lipo-proteinosis induced by inhaled quartz.

Abstract Specific pathogen-free rats, exposed to the inhalation of quartz for varying periods and surviving thereafter for several months, consistently developed alveolar lipo-proteinosis, but not typical silicosis as might have been expected. The overall lipid content of the lungs was much increased, notably the phospholipids and especially dipalmitoyl lecithin (DPL), whilst the lipid-free dry weight rose relatively little. In other rats, receiving brief but intenser exposures and surviving subsequently for a limited period so that the disease would be in an active phase, the rate of incorporation of labelled palmitic acid was measured and its rate of disappearance followed for 4 weeks. As compared with controls, the rate of synthesis of DPL was tripled and its rate of loss doubled. Accumulation of DPL in the lungs may thus be explained as an imbalance between formation and removal, though both are augmented. Our evidence conflicts with the view that the basic defect in alveolar lipo-proteinosis is a diminished capacity for elimination of alveolar secretion. The absolute plasma fatty acid content and the proportions of individual acids were unaffected in treated animals. It may therefore be concluded that the lipid accumulation derives from lung tissue rather than directly from the plasma, and type II epithelial cells appear to be a major source.
Source capacitively coupled compensation technique and its applications

This paper gives the first detailed analyses and derivations of the source capacitively coupled compensation technique. The applications of its useful bandpass and phase-lead features, such as high frequency amplitude compensation amplifier, positive feedback ring oscillator and phase-lead compensation ring oscillator are presented. With this compensation technique the amplifier shows significant bandwidth improvement. The constructed 5 GHz positive feedback (PFB) ring oscillator represents 2-9 dB noise-power product advantage below 10 MHz frequency offset. The compensated negative feedback (NFB) ring oscillator prototype in 0.18 /spl mu/m CMOS process achieves record 10 GHz oscillation frequency.
Assessment of Knowledge of Gingival Disease among the Patients attending Kantipur Dental College, Kathmandu

Background: According to the National pathfinder survey of Nepal 2004, gingival disease is one of the most common oral diseases and if left untreated may lead to tooth loss. Aim: To assess the knowledge of gingival diseases among the patients attending Kantipur Dental College, Kathmandu. Materials and Methods: A cross sectional study was conducted among the patients attending Kantipur Dental College. The study was conducted from July to September 2016 with a sample size of 255. A specially designed questionnaire was used for data collection and SPSS version 20 was used for data analysis. Results: Out of 255 participants, males were 127 in number and females 128. The questionnaire consisted of three domains and it was found that 67.1% had fair knowledge on basic knowledge of gingival diseases, 52.2% had fair knowledge on the etiology of disease and 52.2% had good knowledge on the treatment of gum diseases. While applying chi-square test, age and knowledge on all the three domains of disease were statistically significant whereas gender and knowledge were statistically insignificant. Conclusion: This study showed that the level of knowledge among the studied population regarding gingival diseases was fair.