Miracle-dz/UniFAR-FTUs huggingface dataset:
Determination of the Potential Benefit of Time-Frequency Gain Manipulation

Objective: The purpose of this study was to determine the maximum benefit provided by a time-frequency gain-manipulation algorithm for noise-reduction (NR) based on an ideal detector of speech energy. The amount of detected energy necessary to show benefit using this type of NR algorithm was examined, as well as the necessary speed and frequency resolution of the gain manipulation. Design: NR was performed using time-frequency gain manipulation, wherein the gains of individual frequency bands depended on the absence or presence of speech energy within each band. Three different experiments were performed: (1) NR using ideal detectors, (2) NR with nonideal detectors, and (3) NR with ideal detectors and different processing speeds and frequency resolutions. All experiments were performed using the Hearing-in-Noise test (HINT). A total of 6 listeners with normal hearing and 14 listeners with hearing loss were tested. Results: HINT thresholds improved for all listeners with NR based on the ideal detectors used in Experiment I. The nonideal detectors of Experiment II required detection of at least 90% of the speech energy before an improvement was seen in HINT thresholds. The results of Experiment III demonstrated that relatively high temporal resolution (<100 msec) was required by the NR algorithm to improve HINT thresholds. Conclusions: The results indicated that a single-microphone NR system based on time-frequency gain manipulation improved the HINT thresholds of listeners. However, to obtain benefit in speech intelligibility, the detectors used in such a strategy were required to detect an unrealistically high percentage of the speech energy and to perform the gain manipulations on a fast temporal basis.
Periostin (POSTN) Regulates Tumor Resistance to Antiangiogenic Therapy in Glioma Models

Periostin (POSTN) interacts with multiple integrins to coordinate a variety of cellular processes, including epithelial-to-mesenchymal transition (EMT) and cell migration. In our previous study, anti-VEGF-A therapy was associated with resistance and EMT. This study sought to determine the role of POSTN in the resistance of glioma stem cells (GSC) to antiangiogenic therapy. In mouse xenograft models of human glioma, POSTN expression was associated with acquired resistance to anti-VEGF-A therapy and had a synergistic effect with bevacizumab in prolonging survival and decreasing tumor volume. Resistance to anti-VEGF-A therapy regulated by POSTN was associated with increased expression of TGFβ1 and hypoxia-inducible factor-1α (HIF1α) in GSCs. At the molecular level, POSTN regulated invasion and expression of EMT (caveolin-1) and angiogenesis-related genes (HIF1α and VEGF-A) through activation of STAT3. Moreover, recombinant POSTN increased GSC invasion. Collectively, our findings suggest that POSTN plays an important role in glioma invasion and resistance to antiangiogenic therapy. Mol Cancer Ther; 15(9); 2187–97. ©2016 AACR.
A multi-stage approach to clustering and imputation of gene expression profiles

MOTIVATION Microarray experiments have revolutionized the study of gene expression with their ability to generate large amounts of data. This article describes an alternative to existing approaches to clustering of gene expression profiles; the key idea is to cluster in stages using a hierarchy of distance measures. This method is motivated by the way in which the human mind sorts and so groups many items. The distance measures arise from the orthogonal breakup of Euclidean distance, giving us a set of independent measures of different attributes of the gene expression profile. Interpretation of these distances is closely related to the statistical design of the microarray experiment. This clustering method not only accommodates missing data but also leads to an associated imputation method. RESULTS The performance of the clustering and imputation methods was tested on a simulated dataset, a yeast cell cycle dataset and a central nervous system development dataset. Based on the Rand and adjusted Rand indices, the clustering method is more consistent with the biological classification of the data than commonly used clustering methods. The imputation method, at varying levels of missingness, outperforms most imputation methods, based on root mean squared error (RMSE). AVAILABILITY Code in R is available on request from the authors.
KEKERASAN TERHADAP PEREMPUAN DALAM FILM INDONESIA

This study aimed to analyze the depiction of violence experienced by women in the film "7 heart, 7 love, 7 women". These research method used textual analyses to interpret the signs that are produced in a media text are elements of violence experienced by women. The results showed that violence to the women include (a) physical violence, among others: strangling, pulling, injuring a pregnant woman, and rape, (b) symbolic violence, among others: (1) psychological violence: deceive, insult, infidelity; (2) financial violence: lack of accountability husband; (3) functional violence: restrictions on women's social role as executor of reproductive function.
Comparison of Retinal Nerve Fiber Layer Thickness In Vivo and Axonal Transport after Chronic Intraocular Pressure Elevation in Young versus Older Rats

Purpose To compare in young and old rats longitudinal measurements of retinal nerve fiber layer thickness (RNFLT) and axonal transport 3-weeks after chronic IOP elevation. Method IOP was elevated unilaterally in 2- and 9.5-month-old Brown-Norway rats by intracameral injections of magnetic microbeads. RNFLT was measured by spectral domain optical coherence tomography. Anterograde axonal transport was assessed from confocal scanning laser ophthalmolscopy of superior colliculi (SC) after bilateral intravitreal injections of cholera toxin-B-488. Optic nerve sections were graded for damage. Results Mean IOP was elevated in both groups (young 37, old 38 mmHg, p = 0.95). RNFL in young rats exhibited 10% thickening at 1-week (50.9±8.1 µm, p<0.05) vs. baseline (46.4±2.4 µm), then 7% thinning at 2-weeks (43.0±7.2 µm, p>0.05) and 3-weeks (43.5±4.4 µm, p>0.05), representing 20% loss of dynamic range. RNFLT in old rats showed no significant change at 1-week (44.9±4.1 µm) vs. baseline (49.2±5.3 µm), but progression to 22% thinning at 2-weeks (38.0±3.7 µm, p<0.01) and 3-weeks (40.0±6.6 µm, p<0.05), representing 59% loss of dynamic range. Relative SC fluorescence intensity was reduced in both groups (p<0.001), representing 77–80% loss of dynamic range and a severe transport deficit. Optic nerves showed 75–95% damage (p<0.001). There was greater RNFL thinning in old rats (p<0.05), despite equivalent IOP insult, transport deficit and nerve damage between age groups (all p>0.05). Conclusion Chronic IOP elevation resulted in severely disrupted axonal transport and optic nerve axon damage in all rats, associated with mild RNFL loss in young rats but a moderate RNFL loss in old rats despite the similar IOP insult. Hence, the glaucomatous injury response within the RNFL depends on age.
Organizational Correlates of Decline: Some Preliminary Analyses

The roles of organizational slack, flexibility, and variety are considered with respect to the incidence of growth, stability, and decline in college and university enrollments and revenues from 1975 to 1979. HEGIS data are used to classify institutions. HE 015 333 35 pages MF $1.17 PC $5.39
Multidimensionality of Identification: Exploring the Local and Global Experiences of Organizational Members Across Eastern and Western Contexts

This article reports the results of a study based on survey data collected from China and the United States about two employee identifications—local (workgroup/work unit) identification and global (organizational) identification. Since organizational identification consists of local identification and global identification, this study explores the impact of culture on the two identifications. The results indicate that China and the United States present different strengths of local and global identification, and the relationship between these two identifications also diverged in the sample groups.
Developing 3D Imaging Programmes--Workflow and Quality Control

This article reports on a successful project for 3D imaging research, digital applications, and use of new technologies in the museum. The article will focus on the development and implementation of a viable workflow for the production of high-quality 3D models of museum objects, based on the 3D laser scanning and photogrammetry of selected ancient Egyptian artefacts. The development of a robust protocol for the complete process chain for imaging cultural heritage artefacts, from the acquisition of 2D and/or 3D images to the development of interactive applications for the public audience, was a specific objective of the project. The workflow devised by the university museum team combines reference photography and 3D imaging with a curatorial review of the actual object to its digital counterpart. It also integrates methodologies for managing the accompanying metadatasets to record these activities. As final stage deliverables from the process, the museum is making high-quality 3D images of artefacts from its collection available through creation and dissemination of digital 3D multiplatform interactive applications in order to allow remote access and to enhance the museum's public engagement. This short article concludes with practical considerations for a 3D imaging workflow such as time and skills needed, 3D model quality, and expectation management.
Thermal human face recognition based on GappyPCA

Over the last forty years several different techniques have been proposed for human face recognition. This has been used in different application especially in the field, where security is the main concern. Most of the face recognition algorithms work on visual face images. But the visual face images have several drawbacks because the quality of the visual images degrades gradually with the increase of darkness. So, face recognition system doesn't work properly when illumination changes. But thermal infrared camera can capture the same images even in dark situation which means thermal images are illumination independent. We have proposed a GappyPCA based thermal human face recognition technique for frontal face only. The results obtained on testing sets, about 98.61% correct recognition using this technique.
An object tracking system for PTZ cameras using CAM shift

In this paper, we present a robust real-time surveillance system of image object tracking for Pan-Tilt-Zoom(PTZ) camera. For image object tracking, we use the CAM shift tracking algorithm based on the HSI color image distribution of detected moving objects. CAM shift algorithm is very efficient for real-time tracking because of its fast and robust performance. In this system, C++ and OpenCV environment are used for image processing and accessing the PTZ protocol and RS-485 communication for controlling the position of PTZ camera in order to arrange the moving object images in the middle part of the monitor screen. This system can be applied to an effective and fast image surveillance system for continuous object tracking in a wider area.
Anticoagulation for heart failure in sinus rhythm: a Cochrane systematic review.

BACKGROUND Patients with chronic heart failure (heart failure) are at risk of thromboembolic events, and coronary ischaemic events also contribute to the progression of heart failure. Long-term oral anticoagulation is established in certain groups, including patients with heart failure and atrial fibrillation, but there is wide variation in the use of oral anticoagulation in the broader heart failure population. OBJECTIVE To determine whether long-term oral anticoagulation reduces total deaths and/or major thromboembolic events in patients with heart failure. DESIGN Systematic review. DATA SOURCES Reference lists of papers resulting from this search, electronic database searching (MEDLINE, EMBASE, DARE), and abstracts from national and international cardiovascular meetings were studied to identify unpublished studies. Relevant authors of these studies were contacted to obtain further data. SELECTION CRITERIA Randomized controlled trials (RCTs) comparing oral anticoagulants with control or placebo. Non-randomized studies were included, as they may help in assessing side-effects. Other inclusion criteria included duration of treatment > or =1 month, and adults with heart failure due to any underlying cause. Inclusion decisions were duplicated, and disagreement resolved by discussion or a third party. RESULTS One recent pilot RCT compared warfarin, aspirin and no antithrombotic therapy, but no definitive data have yet been published. Three small prospective studies of warfarin in heart failure were also identified, but were over 50 years old, with methods considered unreliable today: in these, anticoagulation was more efficacious than control in reducing all-cause death (OR 0.64; 95%CI 0.45-0.90) and cardiovascular events (OR 0.26; 95%CI 0.16-0.43). Four retrospective non-randomized cohort analyses and three small observational studies of oral anticoagulation in heart failure included differing populations of heart failure patients, and reported contradictory results. CONCLUSIONS Limited evidence from randomized trials and observational studies found a reduction in mortality and cardiovascular events with anticoagulants compared to controls. This evidence should be interpreted with caution. Although oral anticoagulation is indicated in certain groups of patients with heart failure (e.g. atrial fibrillation), the available data do not support its routine use in heart failure patients who remain in sinus rhythm.
Putting cardiovascular disease and vitamin D insufficiency into perspective

The aetiology of CVD is still not completely understood. The present review article summarises data supporting the hypothesis that an insufficient vitamin D status may contribute to the worldwide high prevalence of CVD. Human vitamin D status primarily depends on skin exposure to the UVB spectrum of the sunlight. Epidemiological data indicate that geographic latitude, altitude, season, and the place of residence (urban or rural) are associated with CVD mortality. Interestingly, all these factors also have an influence on human UVB exposure and thus on vitamin D status. Several mechanisms might be responsible for a protective role of vitamin D in CVD. These mechanisms include the inhibition of vascular smooth muscle proliferation, the suppression of vascular calcification, the down regulation of pro-inflammatory cytokines, the up regulation of anti-inflammatory cytokines, and the action of vitamin D as a negative endocrine regulator of the renin–angiotensin system. The first intervention trials indicate that vitamin D may suppress cardiovascular risk markers. However, more controlled clinical trials are needed to investigate whether optimal oral vitamin D supplementation is able to reduce CVD morbidity and mortality.
Improvement of CRF Based Manipuri POS Tagger by Using Reduplicated MWE (RMWE)

This paper gives a detail overview about the modified features selection in CRF (Conditional Random Field) based Manipuri POS (Part of Speech) tagging. Selection of features is so important in CRF that the better are the features then the better are the outputs. This work is an attempt or an experiment to make the previous work more efficient. Multiple new features are tried to run the CRF and again tried with the Reduplicated Multiword Expression (RMWE) as another feature. The CRF run with RMWE because Manipuri is rich of RMWE and identification of RMWE becomes one of the necessities to bring up the result of POS tagging. The new CRF system shows a Recall of 78.22%, Precision of 73.15% and F-measure of 75.60%. With the identification of RMWE and considering it as a feature makes an improvement to a Recall of 80.20%, Precision of 74.31% and F-measure of 77.14%.
Information Mining Based on Fusing Results of Multi-Perspective Cluster-based Summarizations

In this paper, we propose a method to highlight the most important parts of documents, in order to help users to reach to their desired information in information space more beneficially. To do this, the results obtained from a multi-document cluster-based summarization system based upon different perspectives of summarization (such as query-based, general, etc.) are fused in a way that the final results are more informative with respect to the query, in comparison with the results obtained from each prespective of summarization individually. Key-words:Information Mining, Information Retrieval, Fuzzy Document Clustering, Automatic Summarization
Robust Price of Anarchy for Atomic Games with Altruistic Players

htmlabstractWe study the inefficiency of equilibria for various classes of games when players are (partially) altruistic. We model altruistic behavior by assuming that player i's perceived cost is a convex combination of 1-\beta_i times his direct cost and \beta_i times the social cost. Tuning the parameters \beta_i allows smooth interpolation between purely selfish and purely altruistic behavior. Within this framework, we study altruistic extensions of linear congestion games, fair cost-sharing games and valid utility games. We derive (tight) bounds on the price of anarchy of these games for several solution concepts. Thereto, we suitably adapt the smoothness notion introduced by Roughgarden and show that it captures the essential properties to determine the robust price of anarchy of these games. Our bounds reveal that for congestion games and cost-sharing games the worst-case robust price of anarchy increases with increasing altruism, while for valid utility games it remains constant and is not affected by altruism. We also show that the increase in price of anarchy is not a universal phenomenon: for symmetric singleton linear congestion games we derive a bound on the price of anarchy for pure Nash equilibria that decreases as the level of altruism increases. Since the bound is also strictly lower than the robust price of anarchy, it exhibits a natural example in which Nash equilibria are more efficient than more permissive notions of equilibrium.
A 9.5mW analog baseband RX section for 60GHz communications in 90nm CMOS

The analog baseband section of a receiver for high data-rate 60GHz wireless communications is implemented in 90nm CMOS. It consists of the cascade of a 1<sup>st</sup>-order transimpedance amplifier with finely programmable gain, a 4<sup>th</sup>-order source-follower based filter and a coarse gain 1<sup>st</sup>-order programmable gain amplifier, resulting in an overall 6<sup>th</sup>-order selectivity and a 1GHz cut-off frequency. Gain can be programmed from 0dB up to 20dB with 1dB step control, drawing 9.5mA (0–9dB gain range) or 10.8mA (10–20dB gain range) from a 1V supply. A 8.2dBm IIP3 and a −145dBm/Hz IRN are measured respectively at 0dB and 20dB gain. The entire baseband section occupies 400×390µm<sup>2</sup> die area.
Use of reamed locked intramedullary nailing in the treatment of aseptic diaphyseal tibial non-union

Wstêp. Pod wzglêdem czêstoœci zaburzeñ zrostu, od wielu lat, pierwsze miejsce zajmuje koœæ piszczelowa. Obecnie jako metodê z wyboru w leczeniu braku zrostu trzonu piszczeli coraz wiêcej autorów zaleca stabilizacjê z u¿yciem gwoŸdzia œródszpikowego z rozwierceniem jamy szpikowej. Celem pracy by3a ocena przydatnoœci gwoŸdziowania œródszpikowego w leczeniu aseptycznego braku zrostu trzonu piszczeli. Materia3 i metody. Materia3 kliniczny obejmowa3 33 chorych (11 kobiet i 22 mê¿czyzn) leczonych z powodu braku zrostu trzonu goleni za pomoc1 gwoŸdzia œródszpikowego. U 12 chorych stwierdzono brak zrostu typu biologicznie czynnego, a u 21 nieczynny biologicznie. Rozpoznanie stawiano w oparciu o wywiad, badanie kliniczne i badanie radiologiczne. Œredni czas trwania braku zrostu wyniós3 26,96 miesiêcy. GwóŸdŸ œródszpikowy by3 zak3adany zgodnie z technik1 rekomendowan1 przez AO/ASIF. Po zabiegu operacyjnym wszyscy chorzy byli kontrolowani w odstêpach 6-tygodniowych do momentu uzyskania zrostu. Zrost rozpoznawano na podstawie badania fizykalnego i radiologicznego. Wynik funkcjonalny oceniano w oparciu o skalê Johnera i Wruhsa. Za niepowodzenie uznano brak radiologicznych i klinicznych cech postêpuj1cego zrostu w ci1gu 12 miesiêcy po zabiegu operacyjnym. Wyniki. Zrost uzyskano 94% badanych. Œredni czas zrostu wyniós3 37,2 tygodnia. Wed3ug skali Johnera i Wruhsa u 60% chorych odnotowano wyniki dobre i bardzo dobre. U 18% badanych stwierdzono z3y wynik funkcjonalny. U 6 chorych dosz3o do powik3añ infekcyjnych, przy czym u 2 dwóch z nich zaka¿enie przesz3o w formê przewlek31 (u 1 z tych chorych nie uzyskano zrostu). Wniosek. W badanej grupie chorych gwóŸdŸ œródszpikowy by3 skuteczn1 metod1 leczenia aseptycznego braku zrostu trzonu piszczeli. Ze wzglêdu na niewielk1 liczbê chorych ujêtych w analizie wniosek ten nale¿y traktowaæ jako wstêpny.
Effect of Systematic Follow-Up by General Practitioners after Deliberate Self-Poisoning: A Randomised Controlled Trial

Objective To assess whether systematic follow-up by general practitioners (GPs) of cases of deliberate self-poisoning (DSP) by their patients decreases psychiatric symptoms and suicidal behaviour compared with current practice. Design Randomised clinical trial with two parallel groups. Setting General practices in Oslo and the eastern part of Akershus County. Participants Patients aged 18–75 years admitted to hospital for DSP. We excluded patients diagnosed with psychoses, without a known GP, those not able to complete a questionnaire, and patients admitted to psychiatric in-patient care or other institutions where their GP could not follow them immediately after discharge. Intervention The GPs received a written guideline, contacted the patients and scheduled a consultation within one week after discharge, and then provided regular consultations for six months. We randomised the patients to either intervention (n = 78) or treatment as usual (n = 98). Main Outcome Measures Primary outcome measure was the Beck Scale for Suicide Ideation (SSI). Secondary outcomes were Beck Depression Inventory (BDI) and Beck Hopelessness Scale (BHS), self-reported further self-harm and treatment for DSP in a general hospital or an emergency medical agency (EMA). We assessed patients on entry to the trial and at three and six months. We collected data from interviews, self-report questionnaires, and hospital and EMA medical records. Results There were no significant differences between the groups in SSI, BDI, or BHS mean scores or change from baseline to three or six months. During follow-up, self-reported DSP was 39.5% in the intervention group vs. 15.8% in controls (P = 0.009). Readmissions to general hospitals were similar (13% in both groups (P = 0.963), while DSP episodes treated at EMAs were 17% in the intervention group and 7% in the control group (P = 0.103). Conclusion Structured follow-up by GPs after an episode of DSP had no significant effect on suicide ideation, depression or hopelessness. There was no significant difference in repeated episodes of DSP in hospitals or EMAs. However, the total number of incidents of deliberate self-harm reported by the patients was significantly higher in the intervention group. Trial registration Trial registration ClinicalTrials.gov Identifier: NCT01342809