Miracle-dz/UniFAR-FTUs huggingface dataset:
Which renal access technique for percutaneous nephrolithotomy is more difficult to teach using simulation in surgical training?

INTRODUCTION Percutaneous nephrolithotomy (PCNL) is a challenging procedure that urology trainees should be familiar with during residency. Simulators, such as the PERC Mentor, allows the development of this competency in a safer, stress-free environment. There are two primary fluoroscopic methods of gaining percutaneous renal access: the triangulation method and the bull's eye method. Our goal was to assess which method is easier to teach novices by using the PERC Mentor simulator. A secondary goal is to assess differences in subjective and objective outcomes. METHODS Fifteen simulator and procedure-naive medical trainees were randomized into two groups using a crossover, randomized study design. Participants were provided with written, video, in-person demonstrations and hands-on practice for each technique. They then performed each method and were assessed objectively using the PERC Mentor performance data report and subjectively using the PCNL global rating scale (GRS) scoring system. Statistical analysis was performed using Student's T-test and non-parametric Wilcoxon signed rank test. RESULTS There was no statistical difference in the outcomes and complication rates between the two methods. The bull's eye method of obtaining percutaneous access was associated with a significant decrease in operative time (91 seconds vs. 128 seconds, p=0.03) and fluoroscopy time (87 seconds vs, 123 seconds, p=0.03) compared to the triangulation method. CONCLUSIONS Teaching of both techniques was equally well-acquired by students. Both techniques had similar outcomes; however, the bull's eye method was associated with less operative and fluoroscopy time when compared to the triangulation method among novices.
A Taxonomy-Agnostic Approach to Targeted Microbiome Therapeutics—Leveraging Principles of Systems Biology

The study of human microbiomes has yielded insights into basic science, and applied therapeutics are emerging. However, conflicting definitions of what microbiomes are and how they affect the health of the “host” are less understood. A major impediment towards systematic design, discovery, and implementation of targeted microbiome therapeutics is the continued reliance on taxonomic indicators to define microbiomes in health and disease. Such reliance often confounds analyses, potentially suggesting associations where there are none, and conversely failing to identify significant, causal relationships. This review article discusses recent discoveries pointing towards a molecular understanding of microbiome “dysbiosis” and away from a purely taxonomic approach. We highlight the growing role of systems biological principles in the complex interrelationships between the gut microbiome and host cells, and review current approaches commonly used in targeted microbiome therapeutics, including fecal microbial transplant, bacteriophage therapies, and the use of metabolic toxins to selectively eliminate specific taxa from dysbiotic microbiomes. These approaches, however, remain wholly or partially dependent on the bacterial taxa involved in dysbiosis, and therefore may not capitalize fully on many therapeutic opportunities presented at the bioactive molecular level. New technologies capable of addressing microbiome-associated diseases as molecular problems, if solved, will open possibilities of new classes and categories of targeted microbiome therapeutics aimed, in principle, at all dysbiosis-driven disorders.
Marketing Communication Strategy for Coffee Through Digital Marketing

Background: Marketing communication is one step that has a major influence on the success of a company. Along with the development of technology, the economy, and the market, competition becomes more stringent. For this reason, marketing communication media are needed to be able to reach the target market. For this reason, marketing communication media are needed to be able to reach the target market. Aim: This study aims to explain SCI Coffee's marketing communication strategy, which includes message strategy and media strategy, as implemented through Instagram Method: This research uses a descriptive qualitative method. This research was conducted at the café SCI COFFEE. The population and sample used were all workers at the Syntax Corporation Indonesia office, totaling 100 respondents. Findings: The results of the message strategy research study conducted by SCI via Instagram are information contained in the form of a service model that is close to consumers, offers a place with a comfortable atmosphere, and has a unique café concept that is different in each branch. While the message strategy is through creative message forms in the form of unique photo content and captions. The choice of language for writing captions uses slang. The media strategy carried out by SCI through Instagram as a marketing communication medium, media strategy through target audiences that are tailored to the habits of the target audience, using the current trending Instastory feature, and the hashtag feature to make it easier for consumers to find places to enjoy good coffee, and election Instagram post time.
Photobiomodulation and Its Application in Dentistry

Introduction: Photobiomodulation is a promising field in modern minimally invasive dentistry approach which serves as a non-cutting method of using the red to near infrared light on body tissues. PBM consider an excellent alternative or adjunctive to traditional treatment modality. It is a simple and fast to perform, well accepted and tolerated by the patients, that aid in pain relief and reduces inflammation, parallel to the enhanced healing and tissue repair processes. PBM can induce cell proliferation and enhance stem cell differentiation. This impact has direct effects on many stimulatory and protective genes. So this application with these properties was used as adjunctive therapy to the conventional treatment of various diseases and conditions related to soft and hard tooth structure and surrounding tissues. Aim: The purpose of this study is to thorough the light on the applications of PBM therapy in dentistry by understand mechanism of action, with a special focus on stem cells and mechanisms of repair. Methods: A systematic literature review depends on collecting data from an evidence based studies. Searches were made of fifteen electronic databases: the Cochrane Oral Health Group’s Trials Register, The Cochrane Central Register of Controlled Trials (CENTRAL), EMBASE, PsycINFO, Scopus and Web of science, MEDLINE (PubMed). Summary: PBM applications is very promising adjunctive or alternative approach in periodontal, Peri-implant inflammation therapy, orthodontic treatment, temporomandibular joint problems, and with oral medicine lesions, surgical exposure of impacted teeth, pediatric dentistry, crown cementation, dentin hypersensitivity and in gingivectomy, gingivoplasty and frenectomy. LLLT is an easy, simple, shorter chair time, mostly technique accepted by patients and moreover reduce pain intensity, stimulate healing capacity, better coagulation and no need for suturing so gain more patients acceptance. Conclusion: Photobiomodulation is recommended as an alternative for failed standard therapy or as an adjunct modality to treatments. It is a safe and potentially effective on its own thus facilitating easy use. It is a helping device to complete conventional therapy. With superior advantages of easy and faster application, better coagulation, no need for suturing, less swelling and pain and better deepithelialization. However, there is some limitations include cost of the device and it is very difficult to have all the different lasers indicated for different procedures in a private practice.
Direct Simulation of a Self-Similar Turbulent Mixing Layer

Three direct numerical simulations of incompressible turbulent plane mixing layers have been performed. All the simulations were initialized with the same two velocity fields obtained from a direct numerical simulation of a turbulent boundary layer with a momentum thickness Reynolds number of 300 computed by Spalart [J. Fluid Mech. 187, 61 (1988)]. In addition to a baseline case with no additional disturbances, two simulations were begun with two‐dimensional disturbances of varying strength in addition to the boundary layer turbulence. After a development stage, the baseline case and the case with weaker additional two‐dimensional disturbances evolve self‐similarly, reaching visual thickness Reynolds numbers of up to 20 000. This self‐similar period is characterized by a lack of large‐scale organized pairings, a lack of streamwise vortices in the ‘‘braid’’ regions, and scalar mixing that is characterized by ‘‘marching’’ probability density functions (PDFs). The case begun with strong additional two‐dimensional disturbances only becomes approximately self‐similar, but exhibits sustained organized large‐scale pairings, clearly defined braid regions with streamwise vortices that span them, and scalar PDFs that are ‘‘nonmarching. ’’ It is also characterized by much more intense vertical velocity fluctuations than the other two cases. The statistics and structures in several experiments involving turbulent mixing layers are in better agreement with those of the simulations that do not exhibit organized pairings.
Enhancement of the 77 K irreversibility field and critical current density of (Bi,Pb)2Sr2Ca 2Cu3Ox tapes by manipulation of the final cooling rate

By manipulating the cooling rate from the final heat treatment, we have raised the 77 K, self‐field critical current density (Jc) of multifilament (Bi,Pb)2Sr2Ca2Cu3Ox (2223) tapes by a factor of 3, and the irreversibility field (H*) by more than 50%. The Jc of samples cooled in 7.5% O2 from their reaction temperature of 825 °C increased from ∼8 to ∼24 kA/cm2 and H*(77 K) increased from ∼120 to ∼200 mT as the cooling rate was decreased from 5 to 0.016 °C/min. The results unambiguously show that the flux pinning properties of 2223 tapes can be improved by simple changes in wire processing.
Knowledge, Attitude, and Behaviour with Regard to Medication Errors in Intravenous Therapy: A Cross-Cultural Pilot Study

Background: Literature on the prevention of medication errors is growing, highlighting that knowledge, attitude and behavior with regard to medication errors are strategic to planning of educational activities and evaluating their impact on professional practice. In this context, the present pilot study aims to translate and validate nursing professionals’ knowledge, attitudes and behavior (KAB theory) concerning medication administration errors in ICU from English into Persian. Furthermore, two main objectives of the project were: performing a pilot study among Iranian nurses using the translated questionnaire and carrying out a cultural measurement of the KAB theory concerning medication administration errors in an ICU questionnaire across two groups of Italian and Iranian populations. Methods: A cross-cultural adaptation of an instrument, according to the Checklist for reporting of survey studies (CROSS), was performed. The convenience sample was made up of 529 Iranian and Italian registered nurses working in ICU. An exploratory factor analysis was performed and reliability was assessed. A multi-group confirmatory factor analysis was conducted to test the measurement invariance. Ethical approval was obtained. Results: There was an excellent internal consistency for the 19-item scale. Results regarding factorial invariance showed that the nursing population from Italy and Iran used the same cognitive framework to conceptualize the prevention of medication errors. Conclusions: Findings from this preliminary translation and cross-cultural validation confirm that the questionnaire is a reliable and valid instrument within Persian healthcare settings. Moreover, these findings suggest that Italian and Persian nurses used an identical cognitive framework or mental model when thinking about medication errors prevention. The paper not only provides, for the first time, a validated instrument to evaluate the KAB theory in Iran, but it should promote other researchers in extending this kind of research, supporting those countries where attention to medical error is still increasing.
Transport properties and predictive modelling of JET H-mode and optimized shear discharges

An empirical model for anomalous transport in tokamak, supplemented by the proper boundary conditions, has been developed and applied to four different types of JET discharges: ELM-free hot-ion H-mode, L-mode, ELMy H-mode and discharges with optimized magnetic shear. The results of the numerical modelling show that the model gives quite reasonable agreement with experiment in a wide range of plasma parameters and operational regimes. Moreover, they reveal some important generic features of plasma transport which are model independent.
Fiducial and Posterior Sampling

The fiducial coincides with the posterior in a group model equipped with the right Haar prior. This result is generalized here. For this the underlying probability space of Kolmogorov is replaced by a σ-finite measure space and fiducial theory is presented within this frame. Examples are presented that demonstrate that this also gives good alternatives to existing Bayesian sampling methods. It is proved that the results provided here for fiducial models imply that the theory of invariant measures for groups cannot be generalized directly to loops: there exist a smooth one-dimensional loop where an invariant measure does not exist.
Geometric optics-based design of laser beam shapers

When diffraction effects are not important, geometrical optics (ray tracing, conservation of energy within a bundle of rays, and the constant optical path length condition) can be used to design laser beam shapers by solving beam shaping equations or by optimizing a beam shaping merit function for the configurations, including aspheric elements or spherical-surface gradient-index lenses, which are required to change the input irradiance and phase profile into a more useful form. Geometrical optics-based methods are presented for shaping both rotationally and rectangular symmetric laser beam profiles. Solutions of the beam shaping equations are presented for a two-plano-aspheric lens system for shaping a circular symmetric Gaussian beam into a top-hat output beam profile and a two-mirror system with no central obscuration for shaping an elliptical Gaussian input beam into a Fermi-Dirac output beam profile.
Resolution of a diffusion equation describing the acousto-optical interaction in scattering media

The principle of acousto-optic imaging is to combine coherent light and ultrasound in biological tissues to detect optical contrasts with a spatial resolution close to that of echography. Here we propose a model to describe the propagation of acoustically modulated light in a scattering medium. To do so, we derive a correlation diffusion equation from a correlation transport equation making a few approximations. We express solutions of this diffusion equation and compare them with Monte Carlo simulations in the case of uniform and localized insonifications.
Study of Gelatin and Peppermint Oil Nanoemulsion Coating Against Food-Borne Pathogens, as Well as Its Effect on Shrimp Quality and Preservation

ABSTRACT Shrimps are perishable food that can degrade quickly. The effects of a gelatin-based nontoxic antimicrobial compound combined with a peppermint oil nanoemulsion on the quality and shelf life of shrimp during storage were examined. The prepared nanoemulsion has satisfactory physical characteristics like size (115 ± 3.7 nm), polydispersity index (0.632), ζ-potential (−24.76 mV), and whiteness index (86.19). The nanoemulsion has antibacterial and antibiofilm activities in vitro against two important food-borne pathogens, Escherichia coli O157:H7 and Staphylococcus aureus. Nanoemulsion coating could be an excellent choice for preservation of shrimp as it reduces the overall microbial load, protein oxidation, melanosis, lipid oxidation, and pH of shrimp.
SOME MATHEMATICAL MODELS ARISING IN NANO- AND BIO-TECHNOLOGY

In this thesis, three mechanical models arising from nanoscale and biological systems are investigated, namely the dynamics of various nanostructures, the axial buckling of carbon nanotubes and nanopeapods, and the worm-like chain model for stretched semi-flexible molecules and the utilization of such a model for investigating molecular stretching in the connective tissue extracellular matrix. In nanomechanics, we investigate the motion of both a carbon atom inside a carbon nanotube and a C60 fullerene inside a carbon nanotube [4]. We assume a continuous model for which the atoms are assumed to be smeared across the surface of the molecule, so that the pairwise molecular energy can be approximated by performing surface integrals. The spiral path of the atom is found to be stable, but the spiral path of the C60 fullerene is shown to only exist for a few picoseconds. Next, we investigate the motion of a nanoscale tippe top spinning on the interior of a single-walled carbon nanotube in the presence of a variable magnetic field [5]. Unlike the classical tippe top, the nanoscale tippe top does not flip over since the gravitational effect is insignificant at the nanoscale. After the precession, if we apply an opposite retarding magnetic force at the contact point, then the molecule will return to its original standing position. We next investigate some nanoscale orbiting systems; in particular, we study an atom and a C60 fullerene orbiting around a single infinitely long carbon nanotube and a C60 fullerene orbiting around a C1500 fullerene [3]. We find that the circular orbiting frequencies of the proposed nanosystems are in the gigahertz range and the classification of their orbiting paths is determined numerically.
Natural Image Classification Based on Improved Support Vector Machine

Local image representation based natural image classification is an important task. SIFT descriptors and bag-of-visterm (BOV)method have achieved very good results. Many studies focused on improving the representation of the image, and then use the support vector machine to classify and identify the image category. However, due to support vector machine its own characteristics, it shows inflexible and slower convergence rate for large samples，with the selection of parameters influencing the results for the algorithm very much. Therefore, this paper will use the improved support vector machine algorithm be based on ant colony algorithm in classification step. The method adopt dense SIFT descriptors to describe image features and then use two levels BOV method to obtain the image representation. In recognition step, we use the support vector machine as a classifier but ant colony optimization method is used to selects kernel function parameter and soft margin constant C penalty parameter. Experiment results show that this solution determined the parameter automatically without trial and error and improved performance on natural image classification tasks.
Influence of Milling and Use of Ni and Al Containing Metal Binder in NbC-Based Cermets

This study presents the development of niobium carbide cermets bound to nickel and Ni-12Al (wt%). The use of Ni-12Al (wt%) and Ni aims to replace strategic elements such as cobalt (Co) utilized in tungsten carbide-based cermets. Cermets of different compositions were processed by conventional powder metallurgy. Microstructural analysis with semi-quantitative chemical analysis by EDX, Vickers microhardness and density measurement were performed to evaluate the influence of high energy milling application and sintering temperature on the properties of these cermets. A milling time of 20 min in a planetary mill and sintering temperatures of 1420 ºC or 1450 ºC resulted in homogeneous microstructures, densities close to 90% and hardness of around 1000 HV 1 , showing a potential for use of this material in cutting tools.
Qualitative study of district health board inquiries into mental health related homicide in a New Zealand sample

The aim of this study is to identify the methods and content of hospital-based serious incident reviews involving mental health related homicide where a service user was the perpetrator between 2007 and 2017. Eleven reports were obtained from mental health services in New Zealand’s largest city and thematically analysed. Nine used the London protocol to identify clinical and system factors that may have contributed to the serious incident, but there was considerable variation in the way in which it was applied. Feedback to services was inconsistent. The voices of family members of the victims were largely absent and consideration of cultural context was missing. A structured protocol to specifically address the mental health context in New Zealand and internationally could resolve some of these issues and lead to a process that is more likely to provide comprehensive coverage of relevant matters and produce clear recommendations to effect improvements to services.
A new dynamical core for the Met Office's global and regional modelling of the atmosphere

A computational scheme suitable for numerical weather prediction and climate modelling over a wide range of length scales is described. Its formulation is non‐hydrostatic and fully compressible, and shallow atmosphere approximations are not made. Semi‐implicit, semi‐Lagrangian time‐integration methods are used. The scheme forms the dynamical core of the unified model used at the Met Office for all its operational numerical weather prediction and in its climate studies. © Crown copyright, 2005. Royal Meteorological Society
Surface photometry of edge-on galaxies. V: The vertical structure of the bar in NGC 4762

Photometrie de surface de la galaxie SO NGC 4762. Les profils de brillance parallelement et perpendiculairement au plan equatorial indiquent que la galaxie comporte quatre composantes distinctes: un bulbe nucleaire, une barre, une lentille et un anneau externe. NGC 4762 semble etre une galaxie barree des premiers types avec une barre vue obliquement et faisant un angle φ=33°±10° avec la ligne de visee. On etudie la structure de la barre et de la lentille
Helio- and asteroseismology

Abstract Observations of solar and stellar oscillations are providing detailed information about stellar interiors. In the case of the Sun the set of observed frequencies is sufficiently detailed and accurate that the properties of the solar interior, such as sound speed, density and internal rotation, can be inferred with substantial precision and resolution. This allows detailed tests of solar modelling, with interesting and to some extent controversial results. Observations of solar-like oscillations in distant stars have started only recently, owing their very small amplitudes. However, developments in ground-based equipment and observations from space are revolutionizing this field, promising greatly increased insight into the structure and evolution of the stars.