Miracle-dz/UniFAR-FTUs huggingface dataset:
Impact of vitamin D on cognitive functions in healthy individuals: A systematic review in randomized controlled clinical trials

Various functions in the central nervous system, such as growth, development, and cognition can be influenced by vitamins and minerals, which are capable of helping to maintain brain health and function throughout life. Cognition is understood as the aspects related to knowledge, learning, and understanding, as well as the ability to develop these functions. A possible association between low levels of vit D and deficit in the performance of cognitive functions in healthy humans or with some pathological condition is discussed. Because of this, the present systematic review analyzed only randomized clinical trials carried out in healthy non-athlete adults about intellectual and/or mental processes involving cognitive functions to identify whether these individuals with different levels of vit D are capable of interfering with the performance of the cognitive function. To do so, we adopted the PRISMA method criteria and registered it in the PROSPERO database. The search was performed in PubMed (MEDLINE), PsycINFO, Science Direct, Scopus, and Web of Science databases, 2,167 records were identified. The 5 most frequent cognitive domains in the selected studies were: processing speed, attention, verbal learning/memory, executive function, and general cognitive functions. We found that there are positive changes in the following domains: verbal memory and verbal working memory, learning memory, attention, executive function, and also cognitive function in general. We highlight the following suggestions for improvements that vitamin D supplementation may promote in the cognitive domains of healthy adults: a) low doses between 400 and 600 IU/d seem to be more effective when compared to doses between 2,400 and 5,000 IU/d and b) food fortification and enrichment with vit D, need further studies, as they seem to be more or as effective as synthetic supplementation. We evident that there is a need for trials that evaluate the control of vit D levels for healthy adult individuals is important, as they have the potential to minimize health problems, especially those involved in the reduction of cognitive abilities. Thus, the development of more clinical trials to obtain satisfactory answers on this topic needs to be encouraged. Systematic review registration https://www.crd. york.ac. uk/PROSPERO/, identifier: CRD42021262413.
Systematic review and meta-analysis of type B aortic dissection involving the left subclavian artery with a Castor stent graft

Objective Despite the rapid development of thoracic endovascular aortic repair (TEVAR), it is still a challenge to maintain the blood flow of the branch arteries above the aortic arch in Stanford type B aortic dissection involving the left subclavian artery (LSA). The Castor stent graft is an integrated, customized, single-branch stent that enables reconstruction of the LSA. The purpose of this systematic review and meta-analysis was to assess the efficacy of the Castor stent graft for type B aortic dissection. Materials and methods An extensive electronic literature search (PROSPERO registration number: CRD42022322146) was undertaken to identify all articles published up to August 2022 that described thoracic aortic repair with branch stents in the treatment of type B aortic dissection involving the LSA. The quality of the included studies was analyzed using the MINORS criteria. The primary outcome measures were the technical success rate, early mortality rate, endoleak rate, and 1-year survival rate. The secondary outcome measures were the stroke rate, left upper extremity ischemia rate, and target vessel patency rate. Results Eleven studies involving 415 patients were eligible for this meta-analysis. The LSA was successfully preserved in all procedures. The technical success rate was 97.5% (95% CI: 0.953–0.991); the intraoperative endoleak rate was 0.1% (95% CI: 0.000–0.012); the intraoperative LSA patency rate was 99.52%; the intraoperative LSA stent deformation and stenosis rate was 0.15% (95% CI: 0.000–0.051); the early type I endoleak rate was 1.6% (95% CI: 0.003–0.035); the 30-day mortality rate was 0.96%; the early reintervention rate was 0.9% (95% CI: 0.000–0.040); and the perioperative stroke rate was 0% (95% CI: 0.000–0.005). The 1-year survival rate was 99.7% (95% CI: 0.976–1.000). The half-year LSA patency rate was 99.3%, the 1-year LSA patency rate was 97.58%, and the 2-year LSA patency rate was 95.23%. During the follow-up period, the leakage rate was 0.3% (95% CI: 0.000–0.017), the incidence of left upper extremity ischemia rate was 0.5% (95% CI: 0.000–0.035), and the deformation and stenosis rate of the LSA stent was 2.2% (95% CI: 0.06–0.046). Conclusion This meta-analysis shows that endovascular repair of type B aortic dissection using the Castor stent-graft may be technically feasible and effective. However, this conclusion needs to be interpreted with caution, as the quality of evidence for all outcomes is between low and very low. Systematic review registration [https://www.crd. york.ac. uk/prospero/], identifier [CRD42022322146].
E2Fs co-participate in cadmium stress response through activation of MSHs during the cell cycle

Cadmium is one of the most common heavy metal contaminants found in agricultural fields. MutSα, MutSβ, and MutSγ are three different MutS-associated protein heterodimer complexes consisting of MSH2/MSH6, MSH2/MSH3, and MSH2/MSH7, respectively. These complexes have different mismatch recognition properties and abilities to support MMR. However, changes in mismatch repair genes (OsMSH2, OsMSH3, OsMSH6, and OsMSH7) of the MutS system in rice, one of the most important food crops, under cadmium stress and their association with E2Fs, the key transcription factors affecting cell cycles, are poorly evaluated. In this study, we systematically categorized six rice E2Fs and confirmed that OsMSHs were the downstream target genes of E2F using dual-luciferase reporter assays. In addition, we constructed four msh mutant rice varieties (msh2, msh3, msh6, and msh7) using the CRISPR-Cas9 technology, exposed these mutant rice seedlings to different concentrations of cadmium (0, 2, and 4 mg/L) and observed changes in their phenotype and transcriptomic profiles using RNA-Seq and qRT-PCR. We found that the difference in plant height before and after cadmium stress was more significant in mutant rice seedlings than in wild-type rice seedlings. Transcriptomic profiling and qRT-PCR quantification showed that cadmium stress specifically mobilized cell cycle-related genes ATR, CDKB2;1, MAD2, CycD5;2, CDKA;1, and OsRBR1. Furthermore, we expressed OsE2Fs in yeasts and found that heterologous E2F expression in yeast strains regulated cadmium tolerance by regulating MSHs expression. Further exploration of the underlying mechanisms revealed that cadmium stress may activate the CDKA/CYCD complex, which phosphorylates RBR proteins to release E2F, to regulate downstream MSHs expression and subsequent DNA damage repairment, thereby enhancing the response to cadmium stress.
The impact of caring for COVID-19 patients on nurse professional identity: A cross-sectional study using propensity score analysis

Objective To examine the impact of caring for COVID-19 patients on the professional identity of nurses. Methods An online survey was conducted between 19 May and 7 August 2020 in 11 Chinese cities, including Dongguan, Foshan, Guangzhou, Hong Kong, Huizhou, Jiangmen, Macao, Shenzhen, Zhaoqing, Zhongshan, and Zhuhai. Propensity score matching was used to adjust for confounding variables between nurses with and without experience caring for COVID-19 patients. To analyze the impact of caring for COVID-19 patients on nurses' professional identity, a nominal logistic regression model was used rather than an ordinal regression model because the parallel regression assumption was violated. Results After propensity score matching, the final sample contained 1,268 participants, including 634 nurses who cared for COVID-19 patients. During the COVID-19 outbreak, 88.6% of nurses had high levels of professional identity. Nurses who cared for COVID-19 patients had the lowest percentage of high score level on the professional identity subscale for “sense of organizational influence,” as did nurses who did not care for COVID-19 patients. The findings indicated that nurses who cared for COVID-19 patients were 17.95 times more likely to have a high professional identity than a low professional identity (95% CI 2.38–135.39, p = 0.005), after completely controlling for the other factors. There were significant differences between nurses who cared for COVID-19 patients and those who did not in scores on the subscales of professional identity, except for the subscales “sense of self-decision-making” (χ2 = 4.85, p = 0.089) and “sense of organizational influence” (χ2 = 4.71, p = 0.095). Conclusion Nurses' professional identity is positively impacted by their experience caring for COVID-19 patients. Caring for COVID-19 patients should be highlighted as an opportunity to enhance nurses' professional identity. To further enhance the professional identity of nurses, we call for visible nursing leadership during the COVID-19 pandemic and improve their working environment.
Influence of multi-dimensional environmental knowledge on residents' waste sorting intention: Moderating effect of environmental concern

With the rapid increase in household waste, environmental degradation becomes more serious. It is imperative to promote waste sorting in China. This study proposes an extended KAB model to explore the impact mechanism of different dimensions of subjective environmental knowledge on urban residents' waste sorting intention. The study also explores the moderating role of environmental concern in the relationship between three types of subjective environmental knowledge and attitude toward waste sorting. Based on 308 valid questionnaires, through structural equation model, multiple regression analysis, and simple slope test, we found that system knowledge, action-related knowledge, and effectiveness knowledge all have positive impacts on residents' attitudes toward waste sorting, and effectiveness knowledge has the most significant impact. Meanwhile, environmental concern positively moderates the relationship between system knowledge, effectiveness knowledge, and attitude toward waste sorting. This study makes an important theoretical contribution to enrich the existing literature on residents' waste sorting behavior and provides theoretical insights for governmental waste sorting policy formulation at the practical level.
Regulation and directed inhibition of ECP production by human neutrophils

Background Neutrophils are involved in the pathophysiology of allergic asthma, where the Eosinophil Cationic Protein (ECP) is a critical inflammatory mediator. Although ECP production is attributed to eosinophils, we reported that ECP is also present in neutrophils from allergic patients where, in contrast to eosinophils, it is produced in an IgE-dependent manner. Given the key role of ECP in asthma, we investigated the molecular mechanisms involved in ECP production as well as the effects induced by agonists and widely used clinical approaches. We also analyzed the correlation between ECP production and lung function. Methods Neutrophils from allergic asthmatic patients were challenged with allergens, alone or in combination with cytokines, in the presence of cell-signaling inhibitors and clinical drugs. We analyzed ECP levels by ELISA and confocal microscopy. Lung function was assessed by spirometry. Results IgE-mediated ECP release is dependent on phosphoinositide 3-kinase, the extracellular signal-regulated kinase (ERK1/2) and the production of reactive oxygen species by NADPH-oxidase. Calcineurin phosphatase and the transcription factor NFAT are also involved. ECP release is enhanced by the cytokines interleukin (IL)-5 and granulocyte macrophage-colony stimulating factor, and inhibited by interferon-γ, IL-10, clinical drugs (formoterol, tiotropium and budesonide) and allergen-specific IT. We also found an inverse correlation between asthma severity and ECP levels. Conclusions Our results suggest the molecular pathways involved in ECP production and potential therapeutic targets. We also provide a new method to evaluate disease severity in asthmatic patients based on the quantification of in vitro ECP production by peripheral neutrophils.
Workplace friendship, employee well-being and knowledge hiding: The moderating role of the perception of Chaxu climate

In recent years, knowledge hiding has become a hot topic in the field of organizational behavior because of its great harm. However, relevant studies have focused only on the negative interpersonal antecedents of knowledge hiding but neglected the inhibition effect of positive informal relationships on the behavior. To fill this gap, the current study develops a moderated mediation model to investigate how and when workplace friendship has a negative impact on knowledge hiding. Drawing on social exchange theory (SET), we propose that workplace friendship inhibits knowledge hiding through the mediating role of employee well-being, with the Perception of Chaxu climate acting as a boundary condition. Using data from a two-wave time-lagged survey of 279 employees in China, the results show that workplace friendship has a negative impact on knowledge hiding behavior. Specifically, workplace friendship inhibits knowledge hiding by satisfied employee well-being, i.e., workplace friendship has a positive impact on employee well-being, while employee well-being has a negative impact on knowledge hiding. Perception of Chaxu Climate moderates the indirect effect, as the level of employee’s Perception of Chaxu climate rises, the direct effect of workplace friendship on employee well-being is stronger, so as the indirect effect of workplace friendship on knowledge hiding. This article explores the mechanisms affecting employee knowledge hiding from a new interpersonal perspective of workplace friendship. It is enlightened that firms should pay attention to the management of workplace friendship, provide employee with opportunities to establish workplace friendship while providing proper guidance on the direction of workplace friendship and improving the quality of it, in order to promote employees’ happiness perception and organizational knowledge management ability.
A New Approach for Affine-Invariant Image Matching

Affine-invariant matching is one of the challenging fields for image matching. Although several algorithms (ASIFT, Fair-SURF) have been proposed and achieved expressive performance, all these method need to simulate perspective changes and exhaust all possible match which is of high computation complexity (O(N2)). In this paper, we proposed a new method to introduce global descriptor to filter out much unnecessary coarse matches for the matching procedure. Specially, the computation complexity of matching procedure in our method reduces significantly to O(N). But, the experiment result shows that the proposed method can achieve comparable performance to ASIFT at much lower cost.
Aspect-Based Sentiment Classification for Detecting the Cognitive Triad Mechanism of Depression

: The cognitive triad mechanism of Beck’s cognitive theory is critical for early diagnosis and prognosis of depression. According to the cognitive triad mechanism, negative views about the self, the future, and the world appear to be routine in depressed people, occurring spontaneously. The challenge in the clinical interview is that the individuals may have trouble explaining their past and current symptoms for a variety of factors, such as the existence of concurrent mental health or medical problems and memory difficulties. The aspect-based sentiment classification technique can help psychologists overcome this difficulty by identifying the cognitive triad pairs {(self, negative), (future, negative), (world, negative)} from the individual's clinical chatbot and social media messages. The proposed multilayer RNN-capsule architecture on Cognitive Triad Dataset (CTD) consists of two layers, i.e., sentiment recognition and aspect identification layers. Through experiments on the CTD, the multilayer RNN-capsule model outperforms the single-layer RNN-capsule model for aspect-based sentiment classification. The accuracy and F1 score of a single-layer RNN-capsule model for aspect-based sentiment classification are 0.857 and 0.858, respectively. The accuracy and F1 score of the sentiment recognition capsule in the multilayer RNN-capsule model are 0.89 and 0.892, while the accuracy and F1 score of the aspect detection capsule are 0.957 and 0.956. Also, the multilayer RNN-capsule model outperforms most of its counterparts like GNN, LSTM, and BiLSTM. More importantly, capsule architecture is capable of producing words containing sentiment and aspect inclinations that reflect the attributes of sentiment and aspect capsules, respectively, without the use of any linguistic knowledge.
Nickel-copper graphene foam prepared by atmospheric pressure chemical vapour deposition for supercapacitor applications

This study reports on Ni and Ni-Cu graphene foam prepared by atmospheric pressure chemical vapour deposition. The Ni-Cu foam alloys were prepared using a three-dimensional (3D) scaffold template of polycrystalline nickel foam which is commonly used as a current collector in supercapacitor electrodes. The morphological, composition and structural characterization of as-grown Ni and Ni-Cu graphene foam were carried out using confocal Raman spectroscopy imaging, scanning electron microscopy (SEM), high-resolution transmission electron microscopy (HR-TEM), energy-dispersive X-ray spectrometer (EDS) and X-ray photoelectron spectroscopy (XPS). The results demonstrated that Ni-Cu graphene foam is mainly monolayer and bilayer as compared to Ni graphene foam which is typically a few-layer graphene. The electrochemical performance of Ni and Ni-Cu graphene foam as current collectors were evaluated in a three-electrode electrochemical cell using 1 M NaSO 4 aqueous electrolyte and porous activated carbon (AC) produced from lightweight material cork ( Quercus suber ) as the active electrode material. The AC on Ni-Cu graphene foam current collectors exhibited a high specific capacitance (250–300 F g −1 at 1 A g −1 ) and good electrochemical stability (94–100% capacitance retention) over 6000 constant charge-discharge cycles at 5 A g −1 .
Size-optimal Steiner points for Delaunay-refinement on curved surfaces

An extension of the restricted Delaunay-refinement algorithm for surface mesh generation is described, where a new point-placement scheme is introduced to improve element quality in the presence of mesh size constraints. Specifically, it is shown that the use of off-centre Steiner points, positioned on the faces of the associated Voronoi diagram, typically leads to significant improvements in the shape- and size-quality of the resulting surface tessellations. The new algorithm can be viewed as a Frontal-Delaunay approach -- a hybridisation of conventional Delaunay-refinement and advancing-front techniques in which new vertices are positioned to satisfy both element size and shape constraints. The performance of the new scheme is investigated experimentally via a series of comparative studies that contrast its performance with that of a typical Delaunay-refinement technique. It is shown that the new method inherits many of the best features of classical Delaunay-refinement and advancing-front type methods, leading to the construction of smooth, high quality surface triangulations with bounded radius-edge ratios and convergence guarantees. Experiments are conducted using a range of complex benchmarks, verifying the robustness and practical performance of the proposed scheme.
A time-domain NIR brain imager applied in functional stimulation experiments

We developed a time-domain brain imager that is based on picosecond diode lasers, a multimode fiber switch and multi-channel time-correlated single photon counting. It allows to record time-resolved diffuse reflectance for 16 source-detector pairs within typically 1 s. Data analysis was based on the evaluation of moments of measured distributions of times of flight of photons. To show the relevance of these moments for achieving depth selectivity, three-dimensional sensitivities of integral, mean time of flight and variance to absorption changes were calculated using a perturbation approach based on the diffusion equation for photon density for a homogeneous semi-infinite medium. It turned out that variance is almost exclusively sensitive to deep layers, whereas the integral reflects changes in deep as well as in superficial layers. The lateral resolution of the imager was demonstrated by a phantom experiment. Results of a motor stimulation experiment on a healthy volunteer strongly suggest that variance reveals mainly the cerebral activation whereas the integral may additionally contain significant systemic contributions.
Phytochemicals and antioxidant profile of Pellacalyx Axillaris

Pellacalyx axillaris (bebuloh) is a mangrove species belongs to Rhizophoraceae family. The ecology of this species takes place across various Southeast Asian countries including Malaysia, Sumatra, Borneo, and the Philippines. In this study, both chemical components and antioxidant activity of different crude extracts from the leaves of P. axillaris have been investigated. Dried powdered leaves of P. axillaris were extracted through hot technique using three solvents of different polarities; n -hexane, ethyl acetate and methanol. Fractionation and purification of n - hexane and ethyl acetate extracts via a series of chromatographic techniques yielded a total of three compounds, namely β-amyrin palmitate (1) , (24 S )-ethylcholesta-5,22,25-trien-3β-ol (2) and palmitic acid (3) . Their structures were identified using spectroscopic methods including Fourier Transfrom Infrared (FTIR), Maas Sspetrometry (MS), I H and 13 C Nuclear Magnetic Resonance (NMR). The total phenolic content (TPC) of the extracts was determined using Folin-Ciocalteu assay and their values were in the range of 299 - 532 mg GA (gallic acid)/100 g. The evaluation of antioxidant activity of different crude extracts through the scavenging of free radical DPPH was in the order of methanol (IC 50 = 34.4 μg/mL) > ethyl acetate (IC 50 = 89.6 μg/mL) > n -hexane (IC 50 = 858.3 μg/mL). A significantly positive correlation (R 2 = 0.997) was obtained between TPC and the DPPH free radical scavenging at a concentration of 125 μg/mL, for all the crude extracts.