Miracle-dz/UniFAR-FTUs huggingface dataset:
Effect of an mHealth weight loss intervention on Healthy Eating Index diet quality: the SMARTER randomised controlled trial

Abstract In the few weight loss studies assessing diet quality, improvements have been minimal and recommended calculation methods have not been used. This secondary analysis of a parallel group randomised trial (regsitered: https://clinicaltrials.gov/ct2/show/NCT03367936) assessed whether self-monitoring with feedback (SM + FB) v. self-monitoring alone (SM) improved diet quality. Adults with overweight/obesity (randomised: SM n 251, SM + FB n 251; analysed SM n 170, SM + FB n 186) self-monitored diet, physical activity and weight. Real-time, personalised feedback, delivered via a study-specific app up to three times daily, was based on reported energy, fat and added sugar intake. Healthy Eating Index 2015 (HEI-2015) scores were calculated from 24-hour recalls. Higher scores represent better diet quality. Data were collected August 2018 to March 2021 and analysed spring 2022. The sample was mostly female (78·9 %) and white (85·4 %). At baseline, HEI-2015 total scores and bootstrapped 95 % CI were similar by treatment group (SM + FB: 63·11 (60·41, 65·24); SM: 61·02 (58·72, 62·81)) with similar minimal improvement observed at 6 months (SM + FB: 65·42 (63·30, 67·20); SM: 63·19 (61·22, 64·97)) and 12 months (SM + FB: 63·94 (61·40, 66·29); SM: 63·56 (60·81, 65·42)). Among those who lost ≥ 5 % of baseline weight, HEI-2015 scores improved (baseline: 62·00 (58·94, 64·12); 6 months: 68·02 (65·41, 71·23); 12 months: 65·93 (63·40, 68·61)). There was no effect of the intervention on diet quality change. Clinically meaningful weight loss was related to diet quality improvement. Feedback may need to incorporate more targeted nutritional content.
Aripiprazole for schizophrenia Systematic review

Results Weincluded10 randomised controlled studies (involvinga total of 4125 patients), but study attritionwas large and the standard of data reportingwaspoor. Comparedwith placebo, aripiprazole treatmentwas associatedwith a significantdecrease in relapse rates, increased compliancewiththe study protocol, and a decrease inprolactinlevels below the expectedvalues.Compared withrisperidone, aripiprazole caused less elevation of prolactin levels and less prolongation ofthe average QTc interval.
Climate change intensified violence in the south-central Andean highlands from 1.5 to 0.5 ka

Abstract The archaeology of the pre-contact Andes provides an ideal study of human responses to climate change given the region's extreme climatic variability, excellent archaeological preservation, and robust paleoclimate records. We evaluate the effects of climate change on the frequency of interpersonal violence in the south-central Andes from ca. 1.5–0.5 ka (AD 470–1540) by comparing incidents of skeletal trauma observed among 2753 crania from 58 sites to rates of ice accumulation at the Quelccaya Glacier. We find that, in the highlands, the odds of identifying inter-personal violence increase on average by a multiplicative factor of 2.4 (1.8–3.2; 95% C.I.) for every 10-centimeter decrease in annual ice accumulation. Our statistical analysis does not detect a relationship between ice accumulation and interpersonal violence rates among coastal or mid-elevation populations. This disparity likely resulted from variable economic and sociopolitical strategies at different elevations. The failure of rain-fed agriculture during periods of drought and concomitant dissolution of organizing polities likely predisposed highland populations to socioeconomic stress and violent competition for limited resources. Conversely, diversity among lowland and midland economies may have buffered against the effect of drought.
Numerical simulation on particles classification trajectory using unsteady tracking

This paper investigated the classifier particles trajectory tracking simulation.Based on the computational fluid dynamics(CFD) theory,discrete particle model(DPM) was used to simulate particles trajectory.The process of particles classification was investigated using particle motion equation integral of time.According to the results of 2D plane particles capturing and sampling,time-varying curves of fine and coarse particles mass flow rates under different conditions and the average mass flow rate of stable stage under each condition were obtained.In addition,the diameter distributions of fine particles under different conditions were studied.In order to verify the validity of the simulation results,classifier performance with air volume of 5500 m3/min,rotator speed of 55 r/min,and feeding rate of 60 kg/s was investigated.The results showed that the error of fine particles mass flow rate simulation was 6.12%. The simulation curve of the fine particles diameter distribution results demonstrated a good agreement with the experiment curve.The relative errors for different particle sizes were presented as the following:8.26% for particles smaller than 30 μm;9.37% for particle sizes in the range of 30 to 100 μm;and 6.54% for particles bigger than 100μm. This research provided a simulation method for prediction of classifier product output and particle diameter distributions under given conditions.
Medical image fusion based on regional similarity of wavelet coefficients

Based on expatiate wavelet transform principle,a fusion method based on regional similarity of wavelet coefficients was proposed.The regional similarity was defined by means of mean,variance and covariance of decomposition coefficients,the matching degree and adding coefficient could be gained,and then the fusion calculation of high frequency sub-image could be completed.For low frequency sub-image,abstract coefficient was adopted.Finally the fusion image was obtained by taking inverse wavelet transform.The experimental results show this fusion scheme can fuse details of input images successfully,and it can perfectly display information of the each input image,therefore using this image fusion method can get more satisfactory result than using others.
The Optimization of Savonius Helix Wind Turbine Cut-in Speed with the Variation of Blades-twist Rotor and Number of Blades

Wind turbines are typically classified as Horizontal Axis Wind Turbines (HAWT) or Vertical Axis Wind Turbines (VAWT). VAWT has a superior ability to accelerate from rest to rotation than HAWT, allowing it to rotate the rotor even when the wind speed is low; additionally, the produced torque is relatively high. Using the Savonius helix VAWT is one of the numerous methods for enhancing VAWT performance. The effect of the number of blades and the blade twist of the rotor or the angle of rotation of the blades on the rotor from the bottom end to the top end on the speed cut generated by the VAWT Savonius helix was investigated experimentally. Variations in the number of blades used in the study included 2 and 3 blades, as well as 90°, 180°, 270°, and 360° for the rotor twist blades. In a wind tunnel, data was collected at wind speeds ranging from 0 to 5 m/s. The best performance research results were obtained With three blades, a twist angle of 180 degrees, and a cutting speed of 1.51 m/s. By modifying the Savonius Helix VAWT design in this study, it is possible to increase the efficiency and performance of turbines, mainly when used at low wind speeds, and the potential for using wind energy as a more efficient and sustainable alternative energy source.
Energy Balance and Thermal Evolution Analysis of Heat Transfer Fluids of Stirling Engine and Boiler at Focal Point of a Parabolic Solar Concentrator

: A solar concentrator is a technology that converts direct solar radiation into heat. The parabolic concentrator is the best technology for producing electricity from solar energy, because of its high electrical efficiency, about 41%. This technique is the least mature due to the difficulties related to the storage of produced energy. This work concerns a system of two heat receivers, placed at the focus of the parabolic reflector. These two receivers are a boiler and a Stirling engine. The boiler is intended to heat a thermal fluid that will be stored while Stirling engine will produce electricity directly. We studied the thermal balance and the evolution of the temperature of thermal fluids of Stirling engine and the boiler installed at focal point of reflector. The concentrator used is a parabola with surface of 12.6 m². The simulations were carried out in the vicinity of direct radiation measured at 1 pm o'clock local time. The temperature recorded at the focal point varies from 30°C to 900°C for a duration of 80 seconds; when the direct radiation is about 900W/m². This temperature increases from 30°C to 1050°C, for an operating time of 120s. The average temperature of the three fluids in the receiver (permanent fluid in the boiler, heat transfer fluid to be stored, and thermal fluid of Stirling engine) increases from 30°C to over 400°C in less than 1500s. These thermal fluids at this temperature make it possible to operate turbine through the thermal storage system and Stirling engine, to produce electricity.
In situ spectroscopic ellipsometry during atomic layer deposition of Pt, Ru and Pd

The preparation of ultra-thin platinum-group metal films, such as Pt, Ru and Pd, by atomic layer deposition (ALD) was monitored in situ using spectroscopic ellipsometry in the photon energy range of 0.75–5 eV. The metals’ dielectric function was parametrized using a ‘flexible’ Kramers–Kronig consistent dielectric function because it was able to provide accurate curve shape control over the optical response of the metals. From this dielectric function, it was possible to extract the film thickness values during the ALD process. The important ALD process parameters, such as the nucleation period and growth per cycle of Pt, Ru and Pd could be determined from the thickness evolution. In addition to process parameters, the film resistivity in particular could be extracted from the modeled dielectric function. Spectroscopic ellipsometry thereby revealed itself as a feasible and valuable technique to be used in research and development applications, as well as for process monitoring during ALD.
Field and thrust analysis of tubular permanent magnet linear synchronous motor

In this paper,an analytic magnetic field calculation method based on scalar quantity magnet of tubular reference frame with separated variables is introduced,which is a research way to work on the tubular permanent magnet linear synchronous motor with axial magnet.Thanks to this method,an elaborate academic analysis to magnetic field distribution of slotless motor was conducted,whose result showed the axial and radial slot magnetic distributions,while the thrust force of the motor was calculated analytically.Then,finite element analytic method was used to testify the calculation of the magnet and the force.The verification showed that there was almost no difference between the error results produced by both of the above methods.So the validity and practicability of the magnetic field calculation method based on scalar quantity magnet of tubular reference frame with separated variables have been verified,as well as the correctness of the analytic calculation of the thrust force.The radial magnet distributing experiment result of sample motor,whose measurement values are consistent with its calculation values,has been presented.And load sensor has been used to measure the rated load thrust force of the motor,which makes sure the validity of the analysis and designing of the sample motor.
The Difference in Scar-Related Quality of Life in Open Versus Closed Septorhinoplasty

Introduction: The open and closed techniques are the main surgical techniques to perform septorhinoplasty. Although the open technique offers a better view of the pertinent anatomy and facilitates surgical access, it creates an external scar that could affect patients’ satisfaction and quality of life (QoL). This study aims to compare the open and closed techniques using the SCAR-Q patient-reported outcome measure. Methods: In this retrospective study, we have included patients who had their nasal surgery one year ago, in the period between April 2020 and April 2021. The SCAR-Q assessment tool to study patients’ satisfaction with appearance, symptoms, and psychological impact of open and closed septorhinoplasty techniques. Results: A total of 77 patients were included in this analysis. Of these, 39 (50.6%) patients underwent a closed septorhinoplasty, and 38 (49.4%) patients underwent an open approach. The mean (SD) age was 29.6 (8.1) years, and most patients were females (59.7%). The overall SCAR-Q questionnaire responses were very positive across all scales in our cohort, the median (IQR) scores were 91.0 (73.0-100.0) for the appearance scale, 89.0 (70.0-100.0) for the symptoms scale, and 100.0 (87.0-100.0) for the psychological impact scale. However, we have found no differences in SCAR-Q scores regarding appearance, symptoms, and psychological impact between open and closed septorhinoplasty. Conclusion: We have found no significant differences in QoL between open and closed techniques of septorhinoplasty. Larger studies are needed to further validate this finding.
Image completion by exemplar patch

Image completion,especially the completion of large region with complex texture,is one of hot and difficult problems in image processing.Exemplar patch based algorithm is emphatically described.The algorithm combines the ideas of PDE and texture synthesis and patch priorities is computed to decide the fill order.The completion result shows that the algorithm is effective in most examples.
Study on the Optimal Parameters of Image Fusion Based on Wavelet Transform

In order to choose a good wavelet image fusion method in complicated conditions,some wavelet types and levels are analyzed and compared in this paper.Based on the region fusing rule,through calculating the entropy and the standard deviation of fused images,the fusion performances are evaluated.The optimal type and level of wavelet is selected by the experiments of four sorts of images.The experiments show that bior3.9 is the best wavelet in image fusion.
Modified Charlson comorbidity index as a survival prediction tool for older patients after liver transplantation

Purpose An increasing number of older patients now undergo liver transplantation (LT). Although the overall outcomes in older patients are not different from those of younger patients, there is no tool to predict LT prognosis in older patients. We hypothesized that a modified Charlson comorbidity index (mCCI) and 5-factor modified frailty index (mFI-5) can predict outcomes in older patients after LT. Methods This retrospective study included 155 patients (aged >65 years) who underwent LT at Seoul National University Hospital. The recipients were subcategorized into 2 groups based on the mCCI score and mFI-5: the low (0–1) and high (2–5) mCCI groups, and low (≤0.4) and high (>0.4) mFI-5 groups. The independent effect of each variable on post-LT survival was determined using the mCCI subgroup, age at transplantation, sex, Child-Turcotte-Pugh score, model for end-stage liver disease (MELD) score, and mFI-5 subgroup. Results The high-mCCI group (41 patients) showed significantly lower 1- and 3-month and 1-, 3-, and 5-year survival than the low-mCCI group. Using the Cox regression model, the mCCI, sex, and MELD score remained significant. The mFI-5 was not a significant factor to predict patients’ survival. Conclusion The mCCI and MELD scores could be used to predict post-LT survival in older patients.
Real-World Dispensing Patterns of Inhalation Medication in Young Adult Asthma: An Inception Cohort Study

Purpose The Global Initiative for Asthma (GINA) suggests a step-wise approach for pharmacological treatment of asthma. Valid study of real-world treatment patterns using dispensing databases includes proper measurement of medication adherence. We aim to explore such patterns by applying a time-varying proportion of days covered (tPDC)-based algorithm. Patients and Methods We designed a retrospective inception cohort study using the University of Groningen IADB.nl community pharmacy dispensing database. Included were 19,184 young adults who initiated asthma medication anywhere between 1994 and 2021, in the Netherlands. Main treatment steps were defined as: 1 - SABA/ICS-formoterol as needed, 2 - low dose ICS, 3 - low dose ICS + LABA or tiotropium, or intermediate dose ICS, 4 - intermediate to high dose ICS + LABA or tiotropium, triple therapy, or high dose ICS, 5 - treatment prescribed by a specialist. Changes in treatment steps were determined using a time-varying proportion of days covered (tPDC)-based algorithm. Individual drug treatment trajectories were visualized over time using a lasagna plot. Results At initiation, of the 19,184 included individuals, 52%, 7%, 15%, 16%, and 10% started treatment in steps 1 to 5, respectively. The median (IQR) follow-up time was 3 (1–7) years. Median (IQR) number of switches was 1 (0–3). Comparing starting step to last observed step, 37% never switched between treatment steps, 20% of individuals stepped down and 22% stepped up. Conclusion The low proportion of treatment switches between steps indicates that tailoring of treatment to patients’ needs might be suboptimal. The tPDC-based algorithm functions well in translating dispensing data into continuous drug-utilization data, enabling a more granular assessment of treatment patterns among asthma patients.
Systematic review of efficacy and meta-analysis of safety of ranibizumab biosimilars relative to reference ranibizumab anti-VEGF therapy for nAMD treatment

Topic This systematic review and meta-analysis provides a summary of the efficacy and safety of ranibizumab biosimilars relative to reference ranibizumab anti-vascular endothelial growth factor (VEGF) therapy for the treatment of neovascular age-related macular degeneration (nAMD). Methods We conducted systematic searches from January 2003 to August 2022 on Ovid MEDLINE, EMBASE and the Cochrane Controlled Register of Trials. We included studies reporting changes in early treatment diabetic retinopathy study-measured best-corrected visual acuity (BCVA), number of patients who lost or gained more than 15 letters in BCVA from baseline, changes in retinal thickness and adverse events between treatment arms. The following studies were excluded: studies that did not report visual outcomes following biosimilar and reference ranibizumab intravitreal injections, study arms combining anti-VEGF agents with laser or steroid injections, sham injections as a control comparator, studies without English full texts and non-comparative, observational study design. Results Five studies reported on four randomised controlled trials (RCTs) and 1544 eyes at baseline were included in this systematic review and meta-analysis. The studies in our systematic review found no significant differences between reference ranibizumab and ranibizumab biosimilar medications (FYB201, SB11, RanizuRel and Lupin’s ranibizumab) for visual and anatomical outcomes. No significant differences were detected between biosimilar and reference ranibizumab for treatment emergent adverse events (risk ratio, RR 1.06, 95% CI (0.91 to 1.23), p=0.45, I2=52%) or IOP-related adverse events with significant heterogeneity (RR 2.59, 95% CI (0.11 to 62.25), p=0.56, I2=76%). Conclusion This systematic review of four RCTs demonstrated no significant difference in visual outcomes, retinal thickness outcomes, as well as meta-analysis of adverse events between biosimilar and reference ranibizumab therapies for nAMD treatment.
Neuropsychological correlates of visual hallucinatory phenomena in Lewy body disease

Visual hallucinations (VH) ranging from minor to complex, are the most common psychiatric feature of Lewy Body Disease (LBD). Despite their high prevalence and poor prognostic implications instigating extensive research, the precise mechanisms underlying VH remain unclear. Cognitive impairment (CI) is a risk factor and a consistent correlate of VH in LBD. To help shed light on their underlying mechanisms, this study investigates the pattern of CI across the spectrum of VH in LBD.
Depressive Symptoms, Cannabis Use, and Transition Readiness among College Students with and without Chronic Medical Conditions

Abstract Background: College students experience increased responsibility for healthcare transition. They are at increased risk for depressive symptoms and cannabis use (CU), potentially modifiable predictors of successful healthcare transition. This study investigated how depressive symptoms and CU related to transition readiness, and if CU moderated the association between depressive symptoms and transition readiness for college students. Methods: College students (N = 1,826, Mage=19.31, SD = 1.22) completed online measures of depressive symptoms, healthcare transition readiness, and past-year CU. Regression identified 1) the main effects of depressive symptoms and CU on transition readiness and 2) examined if CU moderated the relationship between depressive symptoms and transition readiness with chronic medical conditions (CMC) status as a covariate. Results: Higher depressive symptoms were correlated with past-year CU (r=.17, p<.001) and lower transition readiness (r=-0.16, p<.001). In the regression model, higher depressive symptoms were related to lower transition readiness (ß=-0.02, p<.001); CU was not related to transition readiness (ß=-0.10, p=.12). CU moderated the relationship between depressive symptoms and transition readiness (B=.01, p=.001). The negative relationship between depressive symptoms and transition readiness was stronger for those with no past-year CU (B=-0.02, p<.001) relative to those with a past-year CU (ß=-0.01, p<.001). Finally, having a CMC was related to CU and higher depressive symptoms and transition readiness. Conclusions: Findings highlighted that depressive symptoms may hinder transition readiness, supporting the need for screening and interventions among college students. The finding that the negative association between depressive symptoms and transition readiness was more pronounced among those with past-year CU was counterintuitive. Hypotheses and future directions are provided.