Miracle-dz/UniFAR-FTUs huggingface dataset:
Saturation of Fragmentation During Severe Plastic Deformation

In this review, we focus on the saturation microstructure that evolves during severe plastic deformation (SPD). These nanocrystalline or ultrafinegrained microstructures consist predominantly of high-angle boundaries, although low-angle boundaries are also present. Deformation temperature, alloying, and strain path are the dominant factors controlling the saturation grain size in single-phase materials. The saturation grain size decreases significantly with decreasing deformation temperature, although the dependency is stronger at medium homologous temperatures and less in the lowtemperature regime. The saturation microstructure is sensitive to strain rate at medium temperatures and less so at low temperatures. The addition of alloying elements to pure metals also reduces the saturation grain size. The results indicate that grain boundary migration is the dominant process responsible for the limitation in refinement by SPD. Therefore, second-phase particles of the nanometer scale can stabilize even finer microstructures. This mechanism of stabilization of the microstructure is an effective tool for overcoming the limit in refinement of single-phase materials by SPD. The improved thermal stability of the obtained nanostructures is another benefit of the introduction of second-phase particles.
Scavenger: Automating the construction of application-optimized memory hierarchies

High-level abstractions separate algorithm design from platform implementation, allowing programmers to focus on algorithms while building increasingly complex systems. This separation also provides system programmers and compilers an opportunity to optimize platform services for each application. In FPGAs, this platform-level malleability extends to the memory system: unlike general-purpose processors, in which memory hardware is fixed at design time, the capacity, associativity, and topology of FPGA memory systems may all be tuned to improve application performance. Since application kernels often use few memory resources, substantial memory capacity may be available to the platform for use on behalf of the user program. In this work, we perform an initial exploration of methods for automating the construction of these application-specific memory hierarchies. Although exploiting spare resources can be beneficial, naïvely consuming all memory resources may cause frequency degradation. To relieve timing pressure in large BRAM structures, we provide microarchitectural techniques to trade memory latency for design frequency. We demonstrate, by examining both hand-assembled and HLS-compiled benchmarks, that our application-optimized memory system can improve pre-existing application runtime by 25% on average.
Systems biology network-based discovery of a small molecule activator BL-AD008 targeting AMPK/ZIPK and inducing apoptosis in cervical cancer

The aim of this study was to discover a small molecule activator BL-AD008 targeting AMPK/ZIPK and inducing apoptosis in cervical cancer. In this study, we systematically constructed the global protein-protein interaction (PPI) network and predicted apoptosis-related protein connections by the Naïve Bayesian model. Then, we identified some classical apoptotic PPIs and other previously unrecognized PPIs between apoptotic kinases, such as AMPK and ZIPK. Subsequently, we screened a series of candidate compounds targeting AMPK/ZIPK, synthesized some compounds and eventually discovered a novel dual-target activator (BL-AD008). Moreover, we found BL-AD008 bear remarkable anti-proliferative activities toward cervical cancer cells and could induce apoptosis by death-receptor and mitochondrial pathways. Additionally, we found that BL-AD008-induced apoptosis was affected by the combination of AMPK and ZIPK. Then, we found that BL-AD008 bear its anti-tumor activities and induced apoptosis by targeting AMPK/ZIPK in vivo. In conclusion, these results demonstrate the ability of systems biology network to identify some key apoptotic kinase targets AMPK and ZIPK; thus providing a dual-target small molecule activator (BL-AD008) as a potential new apoptosis-modulating drug in future cervical cancer therapy.
Dysarthric speech characteristics of Thai stroke patients assessed by the computerized articulation test

The dysarthric speech characteristics of 14 Thai stroke patients were assessed by the Computerized Articulation Test [1]. Speech accuracy and error pattern were analyzed. Vowels and tonal characteristics were the most intact characteristics, while reduction of the clusters was the most impaired feature. Both initial and final consonants were frequently substituted, followed by omission and distortion. Generally, low and mid tone, unaspirated consonants and final consonant, monophthong vowels were produced more precisely than the other features.
Active Proxy-G: Optimizing the Query Execution Process in the Grid

The Grid environment facilitates collaborative work and allows many users to query and process data over geographically dispersed data repositories. Over the past several years, there has been a growing interest in developing applications that interactively analyze datasets, potentially in a collaborative setting. We describe the Active Proxy-G service that is able to cache query results, use those results for answering new incoming queries, generate subqueries for the parts of a query that cannot be produced from the cache, and submit the subqueries for final processing at application servers that store the raw datasets. We present an experimental evaluation to illustrate the effects of various design tradeoffs. We also show the benefits that two real applications gain from using the middleware.
Data Services for Carpooling Based on Large-Scale Traffic Data Analysis

With the social development and vehicle increasing, traffic congestion becomes a pressing problem. Carpooling is one solution for traffic congestion. This paper begins with a motivation case and proposes a service-based method to automatically identify vehicles which travel together (i.e., Traveling companion) and provide carpooling candidates for users in heavy urban traffic. This paper focuses on services design and implementation of the carpooling functions in a distributed parallel computing environment. Through a comprehensive evaluation by experiments, our proposal is shown to deliver good efficiency and effectiveness.
Hippocampal Neurogenesis, Depressive Disorders, and Antidepressant Therapy

There is a growing body of evidence that neural stem cells reside in the adult central nervous system where neurogenesis occurs throughout lifespan. Neurogenesis concerns mainly two areas in the brain: the subgranular zone of the dentate gyrus in the hippocampus and the subventricular zone, where it is controlled by several trophic factors and neuroactive molecules. Neurogenesis is involved in processes such as learning and memory and accumulating evidence implicates hippocampal neurogenesis in the physiopathology of depression. We herein review experimental and clinical data demonstrating that stress and antidepressant treatments affect neurogenesis in opposite direction in rodents. In particular, the stimulation of hippocampal neurogenesis by all types of antidepressant drugs supports the view that neuroplastic phenomena are involved in the physiopathology of depression and underlie—at least partly—antidepressant therapy.
Supplementary signal of SVC for damping torsional oscillation

A method is proposed in this paper to select supplementary signals for a static var compensator in IEEE first benchmark model. Different input output controllability analyses are used to assess the most appropriate supplementary signals for the static var compensator (SVC) for achieving effective damping of torsional oscillations. After placing the SVCs based on their primary functions, the most appropriate input signal for supplementary controller is also selected. The eigenvalues and Hankel singular values of the system are computed incorporating various supplementary signals in the SVC for selecting the best supplementary signal.
An Observed Relationship Between Vestibular Function and Auditory Thresholds in Aircraft-Maintenance Workers

Objective: We sought to examine the vestibular function and whether an association exists between vestibular function and hearing thresholds in a group of military aircraft-maintenance workers with exposures to high levels of noise and organic solvents, relative to two different comparison groups. Methods: Vestibular function (using functional reach) and hearing (with pure-tone audiometry) were assessed in 601 exposed personnel, compared with two unexposed groups (500 technical trade and 391 nontrade). Results: Linear regression model showed that functional reach was slightly better for the comparison groups than the exposed group, with only one group being statistically significant, and there was a significant association between vestibular function and auditory thresholds at 500 and 1000 Hz. Conclusion: This study has demonstrated a relationship between low-frequency hearing loss, vestibular dysfunction, anxiety, and depression in an occupational population.
Damage identification using inverse methods

This paper gives an overview of the use of inverse methods in damage detection and location, using measured vibration data. Inverse problems require the use of a model and the identification of uncertain parameters of this model. Damage is often local in nature and although the effect of the loss of stiffness may require only a small number of parameters, the lack of knowledge of the location means that a large number of candidate parameters must be included. This paper discusses a number of problems that exist with this approach to health monitoring, including modelling error, environmental effects, damage localization and regularization.
Characterization of intermixing at the CdS/CdTe interface in CSS deposited CdTe

CdS/CdTe structures deposited on different substrates are analyzed using transmission electron microscopy (TEM), secondary ion mass spectrometry (SIMS), optical transmission, atomic force microscopy (AFM), X‐ray diffraction (XRD) and photoluminescence (PL). The microstructure of CdTe was found to be independent of CdS crystallinity, and the structural defects at CdS/CdTe interface are generated principally by the lattice mismatch between CdS and CdTe. The interdiffusion at the CdS/CdTe interface was found to be a function of substrate temperature and CdCl2 heat treatment.
Degrees of freedom of an electromagnetic wave

We present a rigorous formalism for evaluating the degrees of freedom (d.o.f.) in communication with electromagnetic waves. We show that, although in principle there is an infinity of d.o. f. , the effective number is finite. This is in agreement with the restricted classical theories. We further show that the best transmitting functions are the solutions of a specific eigenvalue equation. The analysis is valid for electromagnetic waves under arbitrary boundary conditions communicating between domains in 3D space. The practical implications of this theory will be discussed.
Algorithmic Foundation of Spectral Rarefaction for Measuring Satellite Imagery Heterogeneity at Multiple Spatial Scales

Measuring heterogeneity in satellite imagery is an important task to deal with. Most measures of spectral diversity have been based on Shannon Information theory. However, this approach does not inherently address different scales, ranging from local (hereafter referred to alpha diversity) to global scales (gamma diversity). The aim of this paper is to propose a method for measuring spectral heterogeneity at multiple scales based on rarefaction curves. An algorithmic solution of rarefaction applied to image pixel values (Digital Numbers, DNs) is provided and discussed.
A Compact Representation for Articulated Human Motion ( sap 0505 )

The MPEG-4 standard comprises a standard pipeline for efficient compression of human motion [Capin et al. 2000]. [Arikan 2006] proposes a lossy compression algorithm for mocap data based on curve simplification using 3D Bezier curve fitting and clustered PCA coding. The major drawback to these approaches is that they fail to exploit structural information of the human figure. Higher compression ratios can be achieved by addressing this issue. [Lee and Lasenby 2006] developed a framework based on wavelet decomposition, where more wavelet coefficients are used to represent more significant joints in a given motion. However, sliding artifacts on the contacts are observed in very low bit rate cases.
The effects of a somatosensory interventions training on balance in healthy elderly

Background: The somatosensory system plays an important role in balance control and age-related declines in somatosensory function have been implicated in falls incidence. Different types of insole devices have been developed to enhance somatosensory information and improve postural stability. However, they are often too complex and expensive to integrate into daily life and textured surfaces may provide an inexpensive and accessible means to enhance somatosensory input. The aim of this study was to examine the effect of exercise somatosensory on balance elderly. Method: A total of 16 healthy elderly men volunteered for this study and were divided into two groups of somatosensory and control. In the pre and post subjects tests ((limit of stability)) of Biodex system was the difficulty level 8. The overall balance index score was calculated as the balance score. Exercises for both groups 3 weeks, 5 sessions per week were performed. Training session’s time was 1 hour of exercise which was described by Suzuki with the exception that somatosensory Group exercises on the textured surface and control group exercises performed on a flat surface. To analyze data using a repeated-measure analysis of variance and the statistical significance was assessed at p< 0.05 level. Results: Results of statistical analysis showed significant effects of exercise on balance in elderly (P<0.05). Conclusion: According to research findings, practice walking on textured surfaces may stimulate pressure receptors in the feet and increase sensory input from the plantar lead to improved balance in the elderly.
Monotonic Semantic Interpretation

Aspects of semantic interpretation, such as quantifier scoping and reference resolution, are often realised computationally by non-monotonic operations involving loss of information and destructive manipulation of semantic representations. The paper describes how monotonic reference resolution and scoping can be carried out using a revised Quasi Logical Form (QLF) representation. Semantics for QLF are presented in which the denotations of formulas are extended monotonically as QLF expressions are resolved.
Accurate identification of evoked potentials by waveform decomposition using discrete cosine transform modeling

This paper introduces a method for decomposing the component responses of the evoked potentials. The decomposition was realized by zero-pole modeling of the evoked potentials in the discrete cosine transform (DCT) domain. It was found that the DCT coefficients of a component response in the evoked potentials could be modeled sufficiently by a second order transfer function in the DCT domain. The decomposition of the component responses was approached by using partial expansion of the estimated model for the evoked potentials, and the effectiveness of the decomposition method was evaluated both qualitatively and quantitatively. Because of the overlap between the component responses, the proposed method enables an accurate identification of the component responses in the evoked potentials, which is useful for clinical and neurophysiological investigations.
Position paper: BE(Hons) data engineering

This paper describes the UTS view of Data Engineering, and the degree program that has been created to educate Data Engineers. The document describes the guiding philosophies and the key ideas used in designing the program. The design of the program takes advantage of the 3rd, 4th and 5th shifts in engineering education[1]. Namely the shift to emphasizing design (problem solving) (3), the shift to applying education, learning, and social-behavioral sciences research, and the shift to integrating information, computational, and communications technology in education. Mills and Treagast[2] question the relative value of Problem Based or Project Based learning in the Australian context. They quote a comparison of problem-based and project-based learning at tertiary level by Perrenet et al[3]. They noted that the similarities between the two strategies are that they are both based on self-direction and collaboration, and that they both have a multidisciplinary orientation.
Rac GTPase Plays an Essential Role in Exocytosis by Controlling the Fusion Competence of Release Sites

The role of small GTPases of the Rho family in synaptic functions has been addressed by analyzing the effects of lethal toxin (LT) fromClostridium sordellii strain IP82 (LT82) on neurotransmitter release at evoked identified synapses in the buccal ganglion of Aplysia. LT82 is a large monoglucosyltranferase that uses UDP-glucose as cofactor and glucosylates Rac (a small GTPase related to Rho), and Ras, Ral, and Rap (three GTPases of the Ras family). Intraneuronal application of LT (50 nm) rapidly inhibits evoked acetylcholine (ACh) release as monitored electrophysiologically. Injection of the catalytic domain of the toxin similarly blocked ACh release, but not when key amino acids needed for glucosylation were mutated. Intraneuronal application of competitive nucleotide sugars that differentially prevent glucosylation of Rac- and Ras-related GTPases, and the use of a toxin variant that affects a different spectrum of small GTPases, established that glucosylation of Rac is responsible for the reduction in ACh release. To determine the quantal release parameters affected by Rac glucosylation, we developed a nonstationary analysis of the fluctuations in postsynaptic response amplitudes that was performed before and after the toxin had acted or during toxin action. The results indicate that neither the quantal size nor the average probability for release were affected by lethal toxin action. ACh release blockage by LT82 was only caused by a reduction in the number of functional release sites. This reveals that after docking of synaptic vesicles, vesicular Rac stimulates a membrane effector (or effectors) essential for the fusion competence of the exocytotic sites.
Low-Resistive High-Work-Function Gate Electrode for Transparent a-IGZO TFTs

Highly transparent and low-resistive multilayered gate electrodes, MoO3/indium-tin oxide (ITO)/Ag/ ZnS (MIAZ) playing as the high-work-function layer, the nonreactive interface layer, the lateral conduction layer, and the index-matching layer, respectively, have been investigated for the application to the transparent oxide thin-film transistors (TFTs). The transmittance of the optimized MIAZ electrode is 92.46% and the sheet resistance is 7.77 Ω/□. The top gate InGaZnO TFT with this gate electrode shows the mobility of 11.57 cm2/(V · s) and positive Vth of 0.210 V compared with that with single ITO gate electrode of which Vth is -0.086 V.
Mapping Forest Structure and Composition from Low-Density LiDAR for Informed Forest, Fuel, and Fire Management at Eglin Air Force Base, Florida, USA

Abstract Eglin Air Force Base (AFB) in Florida, in the United States, conserves a large reservoir of native longleaf pine (Pinus palustris Mill.) stands that land managers maintain by using frequent fires. We predicted tree density, basal area, and dominant tree species from 195 forest inventory plots, low-density airborne LiDAR, and Landsat data available across the entirety of Eglin AFB. We used the Random Forests (RF) machine learning algorithm to predict the 3 overstory responses via univariate regression or classification, or multivariate k-NN imputation. Ten predictor variables explained ∼ 50% of variation and were used in all models. Model accuracy and precision statistics were similar among the various RF approaches, so we chose the imputation approach for its advantage of allowing prediction of the ancillary plot attributes of surface fuels and ground cover plant species richness. Maps of the 3 overstory response variables and ancillary attributes were imputed at 30-m resolution and then aggregated to the management block level, where they were significantly correlated with each other and with fire history variables summarized from independent data. We conclude that functional relationships among overstory structure, surface fuels, species richness, and fire history emerge and become more apparent at the block level where management decisions are made.
Mechanisms of plasma non‐transferrin bound iron generation: insights from comparing transfused diamond blackfan anaemia with sickle cell and thalassaemia patients

In transfusional iron overload, extra‐hepatic iron distribution differs, depending on the underlying condition. Relative mechanisms of plasma non‐transferrin bound iron (NTBI) generation may account for these differences. Markers of iron metabolism (plasma NTBI, labile iron, hepcidin, transferrin, monocyte SLC40A1 [ferroportin]), erythropoiesis (growth differentiation factor 15, soluble transferrin receptor) and tissue hypoxia (erythropoietin) were compared in patients with Thalassaemia Major (TM), Sickle Cell Disease and Diamond‐Blackfan Anaemia (DBA), with matched transfusion histories. The most striking differences between these conditions were relationships of NTBI to erythropoietic markers, leading us to propose three mechanisms of NTBI generation: iron overload (all), ineffective erythropoiesis (predominantly TM) and low transferrin‐iron utilization (DBA).
Quotations Referenced in Scholarly Monographs

This is the second report in a research program entitled Reference Information Analysis (RIA) , the mission of which is to provide information for use in the design of future electronic library systemes by identifying actual information that users extract from libraries materials. The report explores the extent to which scholars use quotation in developing new knowledge? The materials (12 books printed in english:three in the arts, three in the humanities, and three in science and technologies), the methods and the results of the present inquiry are discussed. The study should identify patterns among quotations that would facilitate design of improved indexing and searching techniques
The role of natural environments in the evolution of resistance traits in pathogenic bacteria

Antibiotics are among the most valuable compounds used for fighting human diseases. Unfortunately, pathogenic bacteria have evolved towards resistance. One important and frequently forgotten aspect of antibiotics and their resistance genes is that they evolved in non-clinical (natural) environments before the use of antibiotics by humans. Given that the biosphere is mainly formed by micro-organisms, learning the functional role of antibiotics and their resistance elements in nature has relevant implications both for human health and from an ecological perspective. Recent works have suggested that some antibiotics may serve for signalling purposes at the low concentrations probably found in natural ecosystems, whereas some antibiotic resistance genes were originally selected in their hosts for metabolic purposes or for signal trafficking. However, the high concentrations of antibiotics released in specific habitats (for instance, clinical settings) as a consequence of human activity can shift those functional roles. The pollution of natural ecosystems by antibiotics and resistance genes might have consequences for the evolution of the microbiosphere. Whereas antibiotics produce transient and usually local challenges in microbial communities, antibiotic resistance genes present in gene-transfer units can spread in nature with consequences for human health and the evolution of environmental microbiota that are largely ignored.