Miracle-dz/UniFAR-FTUs huggingface dataset:
Peer acceptance in the school class and subjective health complaints: a multilevel approach.

BACKGROUND Feeling accepted by peers is important for young people's health but few studies have examined the overall degree of acceptance in school and its health consequences. The purpose of the study was to investigate whether health complaints among Swedish students can be attributed to the acceptance climate in their school class even when the health effects of their own (individual) acceptance score have been taken into account. METHODS The data used were from the Health Behaviour in School-aged Children (HBSC) study for the years 2001 to 2002, 2005 to 2006, and 2009 to 2010, consisting of 13,902 5th-, 7th-, and 9th-grade Swedish students nested into 742 school classes. The statistical analyses were performed by means of linear regression multilevel analysis. RESULTS The results indicated that the variation in subjective health complaints could be ascribed partly to the school-class level (boys: 5.0%; girls: 13.5%). Peer acceptance at the individual level demonstrated a clear association with health: the lower the acceptance, the higher the complaint scores. For girls, but not for boys, the overall degree of peer acceptance in the school class demonstrated a contextual effect on health, net of acceptance at the student level. Interaction analyses also revealed an increasingly favorable health among poorly accepted girls as the acceptance climate in the school class declined. CONCLUSIONS A lower overall degree of peer acceptance in the school class is associated with poorer health among girls. However, girls who themselves feel poorly accepted are not as negatively affected health-wise by a poor acceptance climate, as are well-accepted girls.
Explaining and Forecasting Exchange Rates with Order Flows

This paper summarizes key lessons learned from using models from microstructure finance to explain and forecast exchange rates. The first section is an executive summary, which outlines seven lessons that pertain to how different transaction-flow measures (e.g., interbank flows versus end-user flows) perform in explaining concurrent returns and forecasting future returns. Section 2 addresses three overarching topics, including: (1) how various transaction-flow measures differ, (2) causality between transaction flows and returns and how to think about it, and (3) strategies for pinning down underlying flow drivers. Section 3 addresses empirical results underlying the seven lessons in section 1.
Using Burstable Instances in the Public Cloud

Amazon EC2 and Google Compute Engine (GCE) have recently introduced a new class of virtual machines called "burstable" instances that are cheaper than even the smallest traditional/regular instances. These lower prices come with reduced average capacity and increased variance. Using measurements from both EC2 and GCE, we identify key idiosyncrasies of resource capacity dynamism for burstable instances that set them apart from other instance types. Most importantly, certain resources for these instances appear to be regulated by deterministic token bucket like mechanisms. We find widely different types of disclosures by providers of the parameters governing these regulation mechanisms: full disclosure (e.g., CPU capacity for EC2 t2 instances), partial disclosure (e.g., CPU capacity and remote disk IO bandwidth for GCE shared-core instances), or no disclosure (network bandwidth for EC2 t2 instances). A tenant modeling these variations as random phenomena (as some recent work suggests) might make sub-optimal procurement and operation decisions. We present modeling techniques for a tenant to infer the properties of these regulation mechanisms via simple offline measurements. We also present two case studies of how certain memcached workloads might benefit from our modeling when operating on EC2 by: (i) augmenting cheap but low availability in-memory storage offered by spot instances with backup of popular content on burstable instances, and (ii) temporal multiplexing of multiple burstable instances to achieve the CPU or network bandwidth (and thereby throughput) equivalent of a more expensive regular EC2 instance.
Readings on aphasia in bilinguals and polyglots

Introducing a new hobby for other people may inspire them to join with you. Reading, as one of mutual hobby, is considered as the very easy hobby to do. But, many people are not interested in this hobby. Why? Boring is the reason of why. However, this feel actually can deal with the book and time of you reading. Yeah, one that we will refer to break the boredom in reading is choosing readings on aphasia in bilinguals and polyglots as the reading material.
Employer Branding and Corporate Social Responsibility – a postmodern approach

In the present article we designed an exploratory analysis from a postmodern perspective on employer branding and corporate social responsibility in order to overcome the disciplinary dogmatic approach that is found in the organizational and management studies. Our approach is based on investigating theoretical background for the two concepts that have a relatively recent history and it emphasizes their role of legitimation micro-structures with an organizational -corporate nature, arguing for the thesis that they represent founding micronarratives, with different histories, but similar aims.
Depression : your questions answered

1. Introduction 2. What is depression 3. Diagnosis of depression 4. Different types of depression 5. Depression in special groups 6. Depression and sleep 7. Depression and food 8. Depression and sex 9. Treatment of depression 10. Suicide and self-harm 11. Mental Health Assessment and the Mental Health Act 12. Appendices: useful organisations and websites 13. Further reading 14. List of abbreviations 15. Index
Una revisión de los modelos explicativos de la relación entre el constructo hostilidad-ira-agresión y la enfermedad coronaria

Title: A review of the explicative models which relate the construct hostility/anger/aggression to the coronary heart disease. Abstract: The construct of hostility/anger/aggression (HIA) has been one of the most important factors related to coro- nary heart disease (EC). In the last decades, the evidence has showed the importance of the psychophysiological hypereac- tivity as the mediative mechanism between the construct HIA and the EC. However, there has also been emphasized the relevance of the environmental, constitutional and behav- ioral factors to understand how the construct HIA can pro- duce and increase the pathophysiological processes impli- cated in the EC. In this job, we are going to expound which are the main models proposed to explain the relationship HIA-EC: model of psychosocial vulnerability, models of constitutional vulnerability, model of behavioral health, model of psychophysiological reactivity and transactional model. To conclude, we propose a summary model. This model both consider the most important aspects of the pre- vious models and can be used as a starting point to study some aspects which have not widely been analyzed, like the characteristic of individual response specifity.
Automatic Tuning of Discrete Fourier Transforms Driven by Analytical Modeling

Analytical models have been used to estimate optimal values for parameters such as tile sizes in the context of loop nests. However, important algorithms such as fast Fourier transforms (FFTs) present a far more complex search space consisting of many thousands of different implementations with very different complex access patterns and nesting and code structures. As a results, some of the best available FFT implementations use heuristic search based on runtime measurements. In this paper we present the first analytical model that can successfully replace the measurement in this search on modern platforms. The model includes many details of the platform's memory system including the TLBs, and, for the first time, physically addressed caches and hardware prefetching. The effect, as we show, is a dramatically reduced search time to find the best FFT without significant loss in performance. Even though our model is adapted to the FFT in this paper, its underlying structure should be applicable for a much larger set of code structures and hence is a candidate for iterative compilation.
Nested retrotransposons on the W chromosome of the wild silkworm Bombyx mandarina

The W chromosome of the silkworms Bombyx mori or B. mandarina is recombinationally isolated from the Z chromosome and the autosomes. We previously characterized a female‐specific randomly amplified polymorphic DNA (RAPD), designated W‐Yamato, derived from the W chromosome of the wild silkworm Bombyx mandarina. To further analyse the W chromosome of B. mandarina, we obtained a lambda phage clone that contains the W‐Yamato RAPD sequence and sequenced the 16.7 kb DNA insert. We found that this DNA comprises a nested structure of at least seven elements: six retrotransposons and one transposable element‐like sequence. The transposable element‐like sequence is inserted into a micropia‐like retrotransposon (Karate). The Karate and the non‐long terminal repeat (non‐LTR) retrotransposon BMC1 are inserted into a 412‐like retrotransposon (Judo). Furthermore, this Judo, and two non‐LTR retrotransposons (Kurosawa and Kendo) are inserted into a Pao‐like retrotransposon (Yamato). These results indicate that the retrotransposons inserted into the W chromosome are not efficiently removed but accumulate gradually as strata without recombination.
Acute Auditory Stimulation with Different Styles of Music Influences Cardiac Autonomic Regulation in Men

Background: No clear evidence is available in the literature regarding the acute effect of different styles of music on cardiac autonomic control. Objectives: The present study aimed to evaluate the acute effects of classical baroque and heavy metal musical auditory stimulation on Heart Rate Variability (HRV) in healthy men. Patients and Methods: In this study, HRV was analyzed regarding time (SDNN, RMSSD, NN50, and pNN50) and frequency domain (LF, HF, and LF / HF) in 12 healthy men. HRV was recorded at seated rest for 10 minutes. Subsequently, the participants were exposed to classical baroque or heavy metal music for five minutes through an earphone at seated rest. After exposure to the first song, they remained at rest for five minutes and they were again exposed to classical baroque or heavy metal music. The music sequence was random for each individual. Standard statistical methods were used for calculation of means and standard deviations. Besides, ANOVA and Friedman test were used for parametric and non-parametric distributions, respectively. Results: While listening to heavy metal music, SDNN was reduced compared to the baseline (P = 0.023). In addition, the LF index (ms2 and nu) was reduced during exposure to both heavy metal and classical baroque musical auditory stimulation compared to the control condition (P = 0.010 and P = 0.048, respectively). However, the HF index (ms2) was reduced only during auditory stimulation with music heavy metal (P = 0.01). The LF/HF ratio on the other hand decreased during auditory stimulation with classical baroque music (P = 0.019). Conclusions: Acute auditory stimulation with the selected heavy metal musical auditory stimulation decreased the sympathetic and parasympathetic modulation on the heart, while exposure to a selected classical baroque music reduced sympathetic regulation on the heart.
Effect of Variation in Nestling Hunger Levels on the Begging Behaviour of Nestlings and the Provisioning Behaviour of Adult American Kestrels

Little is known about how variation in nestling begging intensity influences the behaviour of adult raptors and how responses of adult males and females to such variation might differ. Our objective was to manipulate the begging intensity of nestling American Kestrels (Falco sparverius) and examine the responses of adults. We studied 12 pairs of American Kestrels nesting in nest boxes from 1 March to 1 July 2014 at the Blue Grass Army Depot, Madison County, Kentucky. Nest boxes were modified with a separate compartment for a camcorder to record nestling behaviour, and a second camcorder was placed outside the nests to monitor adult behaviour. To manipulate nestling hunger levels, 12 to 26-day-old nestlings in six nests were deprived of food for 24 h and those in the other six nests were fed until satiated. At each nest, we alternated control (no treatment) and treatment (fed or food deprived) days over a 4 day period to minimise the possible effect of nestling age on adult and nestling behaviour. Nestling begging intensity differed among treatments, with nestlings in food-deprived nests begging with greater intensity after food deprivation and those in fed-treatment nests begging with less intensity after being fed. Adult male and female American Kestrels provisioned nestlings at similar rates, with both sexes feeding nestlings at higher rates after food deprivation and at lower rates after fed treatments. Thus, the begging behaviour of nestling American Kestrels varied with hunger level, and adult American Kestrels responded by adjusting provisioning rates. Although the response of adults to nestling begging suggests that natural selection might favour ‘dishonest’ begging to obtain more food, the potential costs of ‘dishonest’ begging, such as attracting predators, reduced immunocompetence, and loss of indirect fitness benefits if such begging negatively impacts siblings and parents, may outweigh any possible benefit.
A compact antenna for IoT applications

Real time weather monitoring in aircraft is gaining its importance in emerging IoT applications. Here a compact microstrip rectangular patch antenna with different slots have been proposed. The slots are introduced to reduce the resonating frequency and to obtain miniaturization of antenna. Here a microstrip patch antenna is developed with resonating frequency in the range of S band. Slots of various shapes are introduced to shift the resonating frequency range to L band. By this we achieve reduction in size of antenna. The antenna uses inset feeding techniques and substrate used is FR4 epoxy. Microstrip patch antenna is simulated by HFSS software.
Febuxostat, an Inhibitor of Xanthine Oxidase, Suppresses Lipopolysaccharide-Induced MCP-1 Production via MAPK Phosphatase-1-Mediated Inactivation of JNK

Excess reactive oxygen species (ROS) formation can trigger various pathological conditions such as inflammation, in which xanthine oxidase (XO) is one major enzymatic source of ROS. Although XO has been reported to play essential roles in inflammatory conditions, the molecular mechanisms underlying the involvement of XO in inflammatory pathways remain unclear. Febuxostat, a selective and potent inhibitor of XO, effectively inhibits not only the generation of uric acid but also the formation of ROS. In this study, therefore, we examined the effects of febuxostat on lipopolysaccharide (LPS)-mediated inflammatory responses. Here we show that febuxostat suppresses LPS-induced MCP-1 production and mRNA expression via activating MAPK phosphatase-1 (MKP-1) which, in turn, leads to dephosphorylation and inactivation of JNK in macrophages. Moreover, these effects of febuxostat are mediated by inhibiting XO-mediated intracellular ROS production. Taken together, our data suggest that XO mediates LPS-induced phosphorylation of JNK through ROS production and MKP-1 inactivation, leading to MCP-1 production in macrophages. These studies may bring new insights into the novel role of XO in regulating inflammatory process through MAPK phosphatase, and demonstrate the potential use of XO inhibitor in modulating the inflammatory processes.
Genetic Control of Susceptibility to Infection with Candida albicans in Mice

Candida albicans is an opportunistic pathogen that causes acute disseminated infections in immunocompromised hosts, representing an important cause of morbidity and mortality in these patients. To study the genetic control of susceptibility to disseminated C. albicans in mice, we phenotyped a group of 23 phylogenetically distant inbred strains for susceptibility to infection as measured by extent of fungal replication in the kidney 48 hours following infection. Susceptibility was strongly associated with the loss-of-function mutant complement component 5 (C5/Hc) allele, which is known to be inherited by approximately 40% of inbred strains. Our survey identified 2 discordant strains, AKR/J (C5-deficient, resistant) and SM/J (C5-sufficient, susceptible), suggesting that additional genetic effects may control response to systemic candidiasis in these strains. Haplotype association mapping in the 23 strains using high density SNP maps revealed several putative loci regulating the extent of C. albicans replication, amongst which the most significant were C5 (P value = 2.43×10−11) and a novel effect on distal chromosome 11 (P value = 7.63×10−9). Compared to other C5-deficient strains, infected AKR/J strain displays a reduced fungal burden in the brain, heart and kidney, and increased survival, concomitant with uniquely high levels of serum IFNγ. C5-independent genetic effects were further investigated by linkage analysis in an [A/JxAKR/J]F2 cross (n = 158) where the mutant Hc allele is fixed. These studies identified a chromosome 11 locus (Carg4, Candida albicans resistance gene 4; LOD = 4.59), and a chromosome 8 locus (Carg3; LOD = 3.95), both initially detected by haplotype association mapping. Alleles at both loci were inherited in a co-dominant manner. Our results verify the important effect of C5-deficiency in inbred mouse strains, and further identify two novel loci, Carg3 and Carg4, which regulate resistance to C. albicans infection in a C5-independent manner.
DesTeller: A System for Destination Prediction Based on Trajectories with Privacy Protection

Destination prediction is an essential task for a number of emerging location based applications such as recommending sightseeing places and sending targeted advertisements. A common approach to destination prediction is to derive the probability of a location being the destination based on historical trajectories. However, existing techniques suffer from the "data sparsity problem", i.e., the number of available historical trajectories is far from sufficient to cover all possible trajectories. This problem considerably limits the amount of query trajectories whose predicted destinations can be inferred. In this demonstration, we showcase a system named "DesTeller" that is interactive, user-friendly, publicly accessible, and capable of answering real-time queries. The underlying algorithm Sub-Trajectory Synthesis (SubSyn) successfully addressed the data sparsity problem and is able to predict destinations for almost every query submitted by travellers. We also consider the privacy protection issue in case an adversary uses SubSyn algorithm to derive sensitive location information of users.
Node coarsening calculi for program slicing

Several approaches to reverse and re-engineering are based upon program slicing. Unfortunately, for large systems, such as those which typically form the subject of reverse engineering activities, the space and time requirements of slicing can be a barrier to successful application. Faced with this problem, several authors have found it helpful to merge control flow graph (CFG) nodes, thereby improving the space and time requirements of standard slicing algorithms. The node-merging process essentially creates a 'coarser' version of the original CFG. The paper introduces a theory for defining control flow graph node coarsening calculi. The theory formalizes properties of interest, when coarsening is used as a precursor to program slicing. The theory is illustrated with a case study of a coarsening calculus, which is proved to have the desired properties of sharpness and consistency.
Prostate stem cell antigen, a presumable organ‐dependent tumor suppressor gene, is down‐regulated in gallbladder carcinogenesis

Gallbladder cancer (GBC) is relatively rare but has a high mortality rate. One candidate molecule which might be involved in GBC development is prostate stem cell antigen (PSCA), a glycosylphosphatidylinositol‐anchored cell surface antigen with a tissue‐specific pattern of expression in the epithelium of several organs, such as the prostate, stomach, bladder, and gallbladder. It is up‐regulated in a number of cancers including prostate, urinary bladder, and pancreatic cancers, while it is down‐regulated in esophageal and gastric cancers, suggesting that PSCA has an oncogenic activity in the former but a tumor suppressor activity in the latter. However, the precise function of PSCA and the regulatory mechanism for its expression in normal and cancer cells are yet to be determined. In this study, immunohistochemical analyses with a specific antibody revealed that PSCA is down‐regulated in non‐neoplastic gallbladder lesions such as cholesterolosis, cholecystolithiasis, and cholecystitis (9/17; 53%), and also in adenocarcinoma (40/44; 91%), a common neoplasm in gallbladder. Analyses of the DNA methylation status in the GBC cell lines by bisulfite‐Pyrosequencing and a reporter assay for the PSCA promoter activity suggested that the down‐regulation is explained, at least partly, by DNA methylation. Moreover, colony formation assay revealed that PSCA has cell‐proliferation inhibition activity in the GBC cell lines, which was also observed in vivo. These lines of in vivo and in vitro evidence suggest that PSCA is acting as a tumor suppressor in GBC development. © 2011 Wiley Periodicals, Inc.
Factor analysis of risk variables associated with metabolic syndrome in adult Asian Indians

Background: Several studies hinted about the clustering of risk variables of the metabolic syndrome (MS) and suggested that the underlying genetic polymorphisms could be responsible for the increasing incidence of coronary heart disease (CHD) in people of Indian origin. Therefore, identification of the components of the MS along with the genetic factors could be one of the aspects to make an attempt to prevent the increasing incidence of CHD. Materials and Methods: Principal component factor analysis (PCFA) was undertaken to identify the components or factors of the MS among the adult (≥30 years) Asian Indians living in and around Calcutta, India. The study comprised 350 adult Asian Indians. Anthropometric measurements were taken, and lipid profiles, blood pressure and fasting blood glucose were measured for each participant. Two genetic polymorphisms, namely, angiotensin converting enzyme (ACE) gene polymorphism (insertion/deletion [I/D]) or ACE (I/D) and apolipoproteinE (Hha I) were also studied. Results: PCFA revealed 3 factors that cumulatively explained 65.39% of the observed variance of the MS by measured variables. The 3 factors identified were lipids and lipoprotein (Factor 1), centripetal fat and blood pressure (Factor 2), and ACE (I/D) polymorphism with blood pressure (Factor 3). Moreover, the first 2 factors, that is, lipids, lipoprotein, centripetal fat, and blood pressures cumulatively explained ~46% (45.94%) of the observed variance of MS in this population. Conclusions: Since more than 1 factor was identified for the MS phenotype, more than 1 physiogenetic mechanism could be accounted for MS in the Asian Indian population.