Miracle-dz/UniFAR-FTUs huggingface dataset:
The role of acupuncture in women with advanced reproductive age undergoing in vitro fertilization-embryo transfer: A randomized controlled trial and follicular fluid metabolomics study

Background: The objective of this study was to determine the efficacy of acupuncture on the outcome of in vitro fertilization (IVF) in elderly infertile patients with kidney qi deficiency, and to explore its possible mechanism from the perspective of pseudo-targeted metabolomics of follicular fluid. Methods: Sixty cases of elderly women undergoing IVF were sampled and randomly divided into 2 equal groups: the treatment and the elderly control (HA) group. In the treatment group, routine ovulation induction combined with acupuncture treatment was used. Routine ovulation induction combined with sham acupuncture was used in the HA group. Reproductive outcomes of the 2 groups were compared. The follicular fluid of patients obtained on the day of oocyte retrieval was analyzed by the ultra-high-performance liquid chromatography-mass spectrometry analysis system. Results: Compared with the HA group, the score of kidney qi deficiency syndrome in the treatment group was significantly decreased, and the 2 PN fertilization rate, high-quality embryo rate and cumulative pregnancy rate were significantly increased (P < .05). Through the identification of target metabolites, 3 metabolic pathways were found to be closely related to the developmental potential of oocytes, namely: Retinol metabolism pathway; Glycine, serine, and threonine metabolism pathway; Glycerophospholipid metabolism pathway. Conclusion: From our findings, acupuncture can improve the quality of oocytes thus bettering the outcome of IVF-assisted pregnancy in elderly patients with kidney qi deficiency. Trial registration: ChiCTR1800018329.
Formation & Evolution of early-types galaxies : Numerical simulations of galaxy mergers

Une simple classification morphologique des galaxies de l'Univers local montre deux grandes familles: (1) les galaxies disques, avec des bras spiraux et dans deux-tiers des cas une barre stellaire; et (2) les galaxies elliptiques et lenticulaires, dites galaxies de type precoce ou early-type galaxies (ETGs), qui sont dominees par une composante stellaire spheroidale. Les galaxies les plus massives de l'Univers local sont les ETGs. Ces galaxies presentent aussi une large variete de dynamique stellaire: elles peuvent avoir un champ de vitesse regulier et aligne avec la photometrie ou perpendiculaire a la photometrie; ne presenter aucune rotation globale; ou alors etre composees de deux disques en contre-rotation l'un par rapport a l'autre (Kinematically Distinct Core ou KDC). Ces signatures dans la dynamique stellaire des ETGs et leur importante masse sont des signes d'interactions passees, en particulier des signes de fusions de galaxies. Le but principal de ma these est d'analyser un large echantillon de simulations numeriques a haute resolution de fusions binaires de galaxies. Ces fusions sont dites "idealisees" car elles ne prennent pas en compte le contexte cosmologique de formation des galaxies : deux galaxies en isolation sont lancees sur une orbite permettant la fusion de ces galaxies, le resultat final attendu de la fusion etant une ETG. L'analyse statistique de ce large echantillon de simulations nous permet de relier les conditions initiales de la fusion a la galaxie finale. J'ai demontre que le rapport de masse entre les spirales initiales et que l'orientation de leurs moments angulaires sont des points essentiels a la formation des ETGs avec peu ou beaucoup de rotation et des KDCs. La morphologie de la spirale (rapport Bulbe/Disque) est aussi un point important pour la formation des KDC mais son impact n'est pas clair et de nouvelles simulations sont necessaires pour conclure. Durant ma these, j'ai aussi etudie l'importance de la resolution dans les simulations numeriques de fusion de galaxies. J'ai montre que le nombre de particules et la taille des cellules utilisees ont une importance preponderante dans les resultats finaux. Une trop faible resolution (i.e. peu de particules et une grille grossiere) ne permet pas de suivre l'evolution rapide du potentiel gravitationnel lors de la fusion. Dans ce cas, certaines particules n'evacuent pas leur moment angulaire vers l'exterieur de la galaxie: la galaxie resultante de la fusion garde ainsi une plus forte rotation. A haute resolution, la dispersion de ces orbites est resolue, la galaxie resultante possede donc une faible rotation et peut former, sous certaines conditions initiales, un KDC.
AI-Optical Character Recognition (OCR) Solution for Streamlining Invoice Processing

: Invoice processing, a crucial yet traditionally labor-intensive business process, often suffers from inefficiency and errors. This research introduces an innovative Artificial Intelligence (AI) and Optical Character Recognition (OCR) integrated system specifically designed to streamline and improve invoice processing. The AI-OCR system showcased high accuracy rates in recognizing both printed and handwritten characters and interpreting various invoice formats. It demonstrated a notable improvement in efficiency, accuracy, scalability, and security over traditional manual processing methods. Moreover, the system provides structured invoice data, paving the way for further analysis and business insights. The long-term assessment showed its ability for continual learning and improvement, signifying its immense potential for transforming invoice processing. While the system presents significant advancements, continued research and development are needed further to enhance its capabilities and adaptability to diverse business needs. This study suggests that the integration of AI and OCR technologies can effectively address the challenges associated with traditional invoice processing, providing a transformative solution.
Restoration of β-GC trafficking improves the lysosome function in Gaucher’s disease

Lysosomes function as a primary site for catabolism and cellular signaling. These organelles digest a variety of substrates received through endocytosis, secretion and autophagy with the help of resident acid hydrolases. Lysosomal enzymes are folded in the endoplasmic reticulum (ER) and trafficked to lysosomes via Golgi and endocytic route. The inability of hydrolase trafficking due to mutations or mutations in its receptor or cofactor leads to cargo accumulation (storage) in lysosomes, resulting in lysosome storage disorder (LSD). In Gaucher’s disease (GD), the lysosomes accumulate glucosylceramide due to a lack of β-glucocerebrosidase (β-GC) activity that causes lysosome enlargement/dysfunction. We hypothesize that improving the trafficking of mutant β-GC to lysosomes may delay the progression of GD. RNAi screen using high throughput based lysosomal enzyme activity assay followed by reporter trafficking assay utilizing β-GC-mCherry lead to the identification of nine potential phosphatases. Depletion of these phosphatases in HeLa cells enhanced the β-GC activity by increasing the folding and trafficking of Gaucher’s mutants to the lysosomes. Consistently, the lysosomes in primary fibroblasts from GD patients restored their function upon the knockdown of these phosphatases. Thus, these studies provide evidence that altering phosphatome activity possibly delays the GD and forms an alternative therapeutic strategy for this genetic disease. Key points Phosphatome RNAi screen identified both activators and inhibitors of cellular glucocerebrosidase activity Depletion of selective phosphatases in HeLa cells improved the folding and trafficking of mutant β-glucocerebrosidase to lysosomes Knockdown of selective phosphatases restored the low basal β-glucocerebrosidase activity to that of wild-type in primary cells derived from Gaucher’s disease patients Depletion of selective phosphatases displayed variable β-GC activity in neuropathic and non-neuropathic Gaucher’s disease patient cells
Climatic change and variability.

It is rre~h in.our memories that in recent years the adverse c11~at'c events have. frcque ntly disrupted the hum an soc ieue s. T he seventy of Sahel ian d rough t. 1968-73, has caught the public attcnuon. More recently the drought has occurred with double inte nsi ty a nd its disastrous efTects h~ve 1l0W spread ove r Ethiopia, Sudan and other nei gh bouring African co untries. III the. 970s, the adverse cl imate beca me a major dcsta bil izing factor III t he nat ion al econo mies a nd the food p~oduct ioll of the world. The year 1972 saw a worl dWIde epidemic . o f costly cl imatic episodes. including dro ught III Ind ia and Soviet Unio n. Flo od years like one in 1974 i n Bangladesh ha ve frequently put heavy demand on international support and rescue to a llevi~te the . disastrous co nsequences. In 1975. co ld waves III Brazil badly damaged eo lTee crops, while in 1976 drought III Europe caused widespread eco no mic probl~ms: The oee~rrenee of extre mely pro nounced EIN II! o m 1982/83.1S another climate related event during which cold nut rient-rich upwelling water ofT the coasts of Peru. Ecuador and Co lombia w~s replaced by wa rm water from the eq.uato nal Pac ific with d isastro us co m equences on fisheries. and excess ive and destructive ra infall along those coasts. Simultaneo usly, major climat ic events like droughts ove r Australia have occurred over several pa~t s of the world. Such extreme clima tic even.t~ du ring past two decades have de mo nstrated the se nsit ivity of human welfa re and international relations to c limatic events.
Solution of fractional Sawada–Kotera–Ito equation using Caputo and Atangana–Baleanu derivatives

In the present work, the fractional‐order Sawada–Kotera–Ito problem is solved by considering nonlocal Caputo and nonsingular Atangana–Baleanu (ABC) derivatives. The methodology used is an application of the Shehu transform and the Adomian decomposition method. The obtained solution is more accurate when using the ABC type derivative as compared to the Caputo sense, when using the proposed ADShTM method (Adomian decomposition Shehu transform method). The results so obtained by the ADShTM using Caputo and ABC operators are compared, establishing the superiority of the proposed method. The numerical results demonstrate that the application of the ABC derivative is not only relatively more effective and reliable but also straightforward to achieve high precision solution.
Decision Support System in Identification of Swallow's Nest Quality with Weighted Product Method

This Decision Support System is related to the Weighted Product method in considering the criteria and weights. The Weighted Product (WP) method is one of the methods used to complete the decision-making system by considering the criteria and weights. Decision making on the quality of the best swallow's nest is that there is no determination criteria so that it does not provide a maximum decision. This method uses equations to connect attributes and only produces the largest value that will be selected as the best alternative. The use of the Weight Product method produces ranking results in accordance with calculations from the manual with both data showing an accuracy rate of 100%. These results are implemented into a website-based decision support system using PHP and Mysql programming in general the system built has been able to run and can produce ranking data well.
Terminal Decline in Well-Being: The Role of Multi-Indicator Constellations of Physical Health and Psychosocial Correlates

Well-being is often relatively stable across adulthood and old age, but typically exhibits pronounced deteriorations and vast individual differences in the terminal phase of life. However, the factors contributing to these differences are not well understood. Using up to 25-year annual longitudinal data obtained from 4,404 now-deceased participants of the nationwide German Socio-Economic Panel Study (SOEP; age at death: M = 73.2 years; SD = 14.3 years; 52% women), we explored the role of multi-indicator constellations of sociodemographic variables, physical health and burden factors, and psychosocial characteristics. Expanding earlier reports, structural equation model (SEM) trees allowed us to identify profiles of variables that were associated with differences in the shape of late-life well-being trajectories. Physical health factors were found to play a major role for well-being decline, but in interaction with psychosocial characteristics such as social participation. To illustrate, for people with low social participation, disability emerged as the strongest correlate of differences in late-life well-being trajectories. However, for people with high social participation, whether or not an individual had spent considerable time in the hospital differentiated high versus low and stable versus declining late-life well-being. We corroborated these results with variable importance measures derived from a set of resampled SEM trees (so-called SEM forests) that provide robust and comparative indicators of the total interactive effects of variables for differential late-life well-being. We discuss benefits and limitations of our approach and consider our findings in the context of other reports about protective factors against terminal decline in well-being.
Constant Interface Temperature Reliability Assessment Method: An Alternative Method for Testing Thermal Interface Material in Products

This Thesis is brought to you for free and open access. It has been accepted for inclusion in Dissertations and Theses by an authorized administrator of PDXScholar. For more information, please contact pdxscholar@pdx.edu. Recommended Citation Amoah-Kusi, Christian, "Constant Interface Temperature Reliability Assessment Method: An Alternative Method for Testing Thermal Interface Material in Products" (2015). Dissertations and Theses. Paper 2295.
Reconsidering Spontaneous Analogical Reasoning through the Knowledge in Pieces Mechanism

University of Lincoln, School of Education, United Kingdom (1) University of Lincoln, School of Education, United Kingdom (2) Abstract Much of the science education literature on analogical reasoning points to the benefits of analogies in helping students familiarize themselves with concepts, phenomena and situations they find abstract and difficult to understand. The conceptual benefits from such a use of analogies seem increasingly clear, as there is evidence from studies in which students were provided with an analogy, were taught how to use and, as a consequence, reached a better understanding of the concept, phenomenon, or situation they were unfamiliar with in the first place. This paper does not contradict the efficacy of such a use of analogies, but shifts attention to students’ spontaneously self-generated analogies, as opposed to taught analogies where students do not generate the analogy but are asked to use and reason with. It discusses how the ‘knowledge-in-pieces framework’, according to which knowledge is viewed as a complex system composed of fundamental knowledge elements that are activated in response to a particular situation, can be used for viewing the relationship and interaction of students’ knowledge with their spontaneous analogical reasoning. Data are drawn from small focus group discussions in which students of the same age group (9-10, 11-12, 12-13, 14-15, 16-17) were asked to explain predictions they made when presented with novel situations they had not seen before. The role of students’ spontaneous analogical reasoning in these explanations is examined along with the knowledge they drew upon in order to make their predictions. The findings underscore the need to consider students’ analogical reasoning and how their existing knowledge affects this reasoning which, in turn, impacts on their understanding of unfamiliar situations and phenomena.
Investigation on the effect of fractal soot aggregation on radiative transfer in homogeneous gas-soot mixture using full-spectrum k-distribution method

The oxy-fuel combustion usually contains multiple complex heat transfer mechanisms, and the thermal radiation is regarded as one of the principal mode of heat transfer in the flame. Dannecker et. al. (Dannecker, et al., 2007) studied the wall heat load at the liner structure of a model gas turbine combustion chamber and pointed out that the radiative heat transfer contributed to 20-30% of the total wall heat flux. Generally, the combustion products that result in the change of the radiative heat transfer in the oxy-fuel combustion flame include a large amount of gaseous species, e.g. CO2 and H2O, which also exist in conventional air combustion, and the increasing concentration of particulate matters, e.g. soot (Guo, et al., 2018; Kangwanpongpan, et al., 2012; Li, et al., 2018). Therefore, to evaluate the heat transfer process of the oxy-fuel combustion flame accurately, the radiative properties of gases and soot in the flame should be studied carefully. Generally, for the gas scattering is ignored due to its small scattering coefficient, the absorption and emitting properties are only considered. The common numerical calculation models used to predict the gas absorption and emitting properties contain Line-By-Line (LBL) model, Band models and Global models (Modest, 2013). The LBL model based on high-resolution spectroscopic databases, e.g. CDSD (Tashkun, et al., 2003) and HITEMP (Rothman, et al., 2010) can most accurately predict the radiative properties in the participating media, but are not mathematical trackable for requiring large computational effort. The Band model is an approximate method which employs the average values of gas radiative properties of the spectral band interval to replace the real value of that interval. Strictly, the Band model is a kind of semi-empirical formula, and the radiative property parameters are hypothetical and simplified. Unlike the LBL model and Band model, the Global model can not only ensure sufficient calculation precision but also be coupled with the radiative transfer equation (RTE) in differential form, which means various
The He/Ne beam diagnostic for line-ratio spectroscopy in the island divertor of Wendelstein 7-X

a versatile gas injection system and an absolute calibrated spectroscopic observation system with more than 200 lines-of-sight have been installed in two divertor locations in the Wendelstein 7-X stellarator. This powerful setup enables among other measurements to infer Te and ne in the divertor region by means of line-ratio spectroscopy on thermal helium. This is a robust and routinely used diagnostic at W7-X and this work describes its main characteristics and shows some examples of Te and ne profiles. In particular it is shown that the inclusion of high Rydberg states in the helium collisional-radiative model is necessary to obtain a realistic estimate of Te. The applicability of the diagnostic is currently being extended towards the low Te and high ne conditions occurring during detachment by means of line-ratio spectroscopy on neon. Initial Te, ne profiles obtained with a neon-beam are here presented.
Intravenous Lidocaine Decreased the Median Effective Concentration of Sufentanil for Tracheal Intubation in Obese Patients

Purpose Sufentanil has been widely used to inhibit the hemodynamic responses caused by tracheal intubation. Using intravenous lidocaine may reduce the dose of sufentanil and better maintain the hemodynamics. This study aimed to determine the effects of intravenous lidocaine on the median effective concentration (EC50) of sufentanil for endotracheal intubation in obese patients. Patients and Methods This is a randomized, double-blind, up-and-down sequential allocation study. Fifty obese patients undergoing bariatric surgery were randomly allocated in a 1:1 ratio into the lidocaine group and the saline group. Anesthesia was induced using a target-controlled infusion of propofol and sufentanil. The effect-site concentration (Ce) of propofol was 3.5 μg/mL. The Ce of sufentanil for the first patient was 0.4 ng/mL, and the sufentanil dose for the next patient was determined according to the responses of the previous patient, using Dixon’s up-and-down sequential method with an interval of 0.05 ng/mL. When the target concentration of propofol and sufentanil was reached, lidocaine 1.5 mg/kg or the same volume of normal saline was infused over 3 min. Tracheal intubation was performed 3 min after the end of the lidocaine or normal saline infusion. Probit regression was used to calculate the EC50 and 95% confidence interval (CI) of sufentanil. Results Thirty-eight patients completed this study. The EC50 of sufentanil was 0.36 ng/mL (95% CI: 0.31–0.41 ng/mL) in the lidocaine group, which was significantly lower than 0.50 ng/mL (95% CI: 0.43–0.62 ng/mL) in the saline group. In addition, compared with saline group, the dosage of sufentanil in lidocaine group decreased significantly during the test. The hemodynamics of the two groups were stable during the study period. Conclusion Intravenous lidocaine 1.5 mg/kg decreased the EC50 of sufentanil required for tracheal intubation in obese patients undergoing bariatric surgery.
On the Treatment of Non-Original Sample Members in the German Household Panel Study (SOEP) Zur Behandlung von Stichproben- Neuzugängen im Sozio-ökonomischen Panel (SOEP)

Household panel studies usually provide data on parents, children, and siblings, but not, e.g., on all ex-partners after a divorce or split in a cohabiting unit. This kind of information, however, can be an interesting source for intergenerational research or, more generally, for research on the dynamics of life course. To the best of our knowledge, among the diverse household panel studies, only the German Socio-Economic Panel (SOEP) contains data on individuals entering a sample household in or after wave two also after leaving that household again. This allows all household members to be traced once having lived in the sample household. In this paper, we discuss the rationale for tracing non-original sample members (Non-OSMs) in household panel studies. We also present results on the incidence and thus the relevance of NonOSMs in the SOEP in general, and for specific research questions in particular.
THE INFLUENCE OF ORGANIZATIONAL CITIZENSHIP BEHAVIOR (OCB) AND ORGANIZATIONAL CULTURE ON THE PERFORMANCE OF EDUCATION EMPLOYEES AS MEDIATED BY JOB SATISFACTION (Survey at the Private University of Sleman Regency in Yogyakarta)

UU No. 12 of 2012 concerning Higher Education, discusses universities that are formed and managed on a non-profit basis, called private universities. The difference between public and private, only the founders and managers, for the form of both are similar. Private Universities need competent human resources to manage themThis type of research is quantitative research. The population of this study was employees at a private university in Sleman Regency, Yogyakarta. The sampling technique that will be used is the proportional stratified random sampling method with a total sample of 130 people. The analysis used is Structural Equation Modeling (SEM) analysis.Based on the results of data analysis, the following conclusions are obtained: (1) Organizational Citizenship Behavior (OCB) has a positive effect on Employee Job Satisfaction; (2) Organizational Culture has a positive effect on Employee Job Satisfaction; (3) Organizational Citizenship Behavior (OCB) has a positive effect on the Performance of Educational Employees of Private Universities in Sleman Regency, Yogyakarta; 4) Organizational Culture has a positive effect on Employee Performance; (5) Job satisfaction has a positive effect on employee performance; (6) Job satisfaction is not able to mediate the effect of the variable Organizational Citizenship Behavior (OCB) on the Performance of Educational Employees at Private Universities in Sleman Regency, Yogyakarta; and (7) job satisfaction is not able to mediate the influence of organizational culture on employee performance Keywords: Organizational Citizenship Behavior (OCB), Organizational Culture, Job Satisfaction, Employee Performance