Miracle-dz/UniFAR-FTUs huggingface dataset:
Radiative divertor and scrape-off layer experiments in open and baffled divertors on DIII-D

Recent progress towards an increased understanding of the physical processes in the divertor and scrape-off layer (SOL) plasmas in DIII-D has been made possible by a combination of new diagnostics, improved computational models and changes in divertor geometry. The work focused primarily on ELMing H mode discharges. The physics of partially detached divertor plasmas, with divertor heat flux reduction by divertor radiation enhancement using D2 puffing, was studied in two dimensions, and a model of the heat and particle transport was developed that includes conduction, convection, ionization, recombination and flows. Plasma and impurity particle flows were measured with Mach probes and spectroscopy and compared with the UEDGE model. The model now includes self-consistent calculations of carbon impurities. Impurity radiation was increased in the divertor and SOL with `puff and pump' techniques using SOL D2 puffing, divertor cryopumping and argon puffing. The important physical processes in plasma-wall interactions were examined with a DiMES (divertor material evaluation system) probe, plasma characterization near the divertor plate and the REDEP code. Experiments comparing single null plasma operation in baffled and open divertors demonstrated a change in the edge plasma profiles. These results are consistent with a reduction in the core ionization source calculated with UEDGE. Divertor particle control in ELMing H mode with pumping and baffling resulted in a reduction in H mode core densities to ne/nGr ≈ 0.25 (with nGr the Greenwald density). Divertor particle exhaust and heat flux were studied as the plasma shape was varied from a lower single null to a balanced double null, and finally to an upper single null.
Development of automaticity in processing L2 collocations: The roles of L1 collocational knowledge and practice condition

Abstract This study examined the development of automaticity in processing L2 collocations, and the roles of L1 collocational knowledge and practice conditions in the development process. Korean learners of English were assigned to one of two practice conditions (practice in identical or varied contexts). The learning gains for word combinations with and without equivalent counterparts in the L1 (L1-only and L2-only collocations) were assessed using response times (RTs) and coefficients of variation (CV) from a phrasal decision task. The results demonstrated that the learners in both groups showed significantly improved collocation processing for both types of items in terms of speed (RT) and automaticity (CV) over time. The RT and CV analyses indicated that both groups’ improvements in collocation processing in the later stages of learning were associated with automatization. Interestingly, L1 collocational knowledge played a facilitative role in processing speed only in the early stages of learning. No reliable evidence for the differential effects of the two types of practice conditions on developing automaticity in collocation processing was found.
MoaE Is Involved in Response to Oxidative Stress in Deinococcus radiodurans

Molybdenum ions are covalently bound to molybdenum pterin (MPT) to produce molybdenum cofactor (Moco), a compound essential for the catalytic activity of molybdenum enzymes, which is involved in a variety of biological functions. MoaE is the large subunit of MPT synthase and plays a key role in Moco synthesis. Here, we investigated the function of MoaE in Deinococcus radiodurans (DrMoaE) in vitro and in vivo, demonstrating that the protein contributed to the extreme resistance of D. radiodurans. The crystal structure of DrMoaE was determined by 1.9 Å resolution. DrMoaE was shown to be a dimer and the dimerization disappeared after Arg110 had been mutated. The deletion of drmoaE resulted in sensitivity to DNA damage stress and a slower growth rate in D. radiodurans. The increase in drmoaE transcript levels the and accumulation of intracellular reactive oxygen species levels under oxidative stress suggested that it was involved in the antioxidant process in D. radiodurans. In addition, treatment with the base analog 6-hydroxyaminopurine decreased survival and increased intracellular mutation rates in drmoaE deletion mutant strains. Our results reveal that MoaE plays a role in response to external stress mainly through oxidative stress resistance mechanisms in D. radiodurans.
Relationship between Novel Elastography Techniques and Renal Fibrosis—Preliminary Experience in Patients with Chronic Glomerulonephritis

Introduction: A renal biopsy represents the gold standard in the diagnosis, prognosis, and management of patients with glomerulonephritis. So far, non-invasive elastographic techniques have not confirmed their utility in replacing a biopsy; however, the new and improved software from Hologic Supersonic Mach 30 is a promising method for assessing the renal tissue’s stiffness and viscosity. We investigated whether this elastography technique could reveal renal tissue fibrosis in patients with chronic glomerulonephritis. Materials and methods: Two-dimensional-shear wave elastography (SWE) PLUS and viscosity plane-wave ultrasound (Vi PLUS) assessments were performed in 40 patients with chronic glomerulopathies before being referred for a renal biopsy. For each kidney, the mean values of five stiffness and viscosity measures were compared with the demographic, biological, and histopathological parameters of the patients. Results: In total, 26 men and 14 women with a mean age of 52.35 ± 15.54 years, a mean estimated glomerular filtration rate (eGFR) of 53.8 ± 35.49 mL/min/1.73m2, and a mean proteinuria of 6.39 ± 7.42 g/24 h were included after providing their informed consent. Out of 40 kidney biopsies, 2 were uninterpretable with inappropriate material and were divided into four subgroups based on their fibrosis percentage. Even though these elastography techniques were unable to differentiate between separate fibrosis stages, when predicting between the fibrosis and no-fibrosis group, we found a cut-off value of <20.77 kPa with the area under the curve (AUC) of 0.860, a p < 0.001 with 88.89% sensitivity, and a 75% specificity for the 2D SWE PLUS measures and a cut-off value of <2.8 Pa.s with an AUC of 0.792, a p < 0.001 with 94% sensitivity, and a 60% specificity for the Vi PLUS measures. We also found a cut-off value of <19.75 kPa for the 2D SWE PLUS measures (with an AUC of 0.789, p = 0.0001 with 100% sensitivity, and a 74.29% specificity) and a cut-off value of <1.28 Pa.s for the Vi PLUS measures (with an AUC 0.829, p = 0.0019 with 60% sensitivity, and a 94.29% specificity) differentiating between patients with over 40% fibrosis and those with under 40%. We also discovered a positive correlation between the glomerular filtration rate (eGFR) and 2D-SWE PLUS values (r = 0.7065, p < 0.0001) and Vi PLUS values (r = 0.3637, p < 0.0211). C reactive protein (CRP) correlates with the Vi PLUS measures (r = −0.3695, p = 0.0189) but not with the 2D SWE PLUS measures (r = −0.2431, p = 0.1306). Conclusion: Our findings indicate that this novel elastography method can distinguish between individuals with different stages of renal fibrosis, correlate with the renal function and inflammation, and are easy to use and reproducible, but further research is needed for them to be employed routinely in clinical practice.
Simulation of cone beam computed tomography chest imaging with parallel computing: nodule detectability versus dose

We have developed a computer simulation model for cone beam computed tomography (CT) chest imagingon a general-purpose personal computer cluster system. Our simulation model incorporates quantum noise, detector blurring, and additive system noise.The main objective is to study how x-ray dose would affect the detectabilityof nodules in simulated cone beam CT chest images. The Radon transforms formalism was used to calculate the projection views for an analytically modeled chest phantom. A parallel random number generator was then used to simulate and add quantum noise whose level depends on the incident x-ray fluence, detector quantum efficiency and pixel size (0.4 mm). We also simulated detector blurring by convolving the noise added images with a Gaussian function matching the modulation transfer function measured for the flat panel x-ray detector studied. Then we modeled the additive system noise and added to the final projection images.The noise level (σ=20) for the additive system noise was calculated from the noise power spectrum of the flat panel detector using the curve-fitting technique.The Feldkamp algorithm with a Gaussian pre-filtering processwas used to reconstruct 3D image data from the projection images.For nodule contrast, the linear attenuation coefficient difference between nodule and lung was set to 10.0%. The diameters for the spherical nodules ranged from 0.2 to 1.7 cm. It was found that our Gaussian pre-filtering process helped reduce the noise level in the reconstructed images and allowed the nodules to be better visualized significantly. At 100,000 photons per pixel (8000 mR total unattenuated exposure at the rotating center), nodules 0.3 mm or larger could be visualized; at 10,000 photons per pixel( 800 mR), nodules 0.5 mm or larger could be visualized; at 2000 photons per pixel (160 mR), only nodules 1.5 mm or larger could be visualized.
Empirical investigation into market power, markups and employment

In this paper I use the production function approach popularized by De Loecker et al. (2020) to analyze the evolution of market power in Slovakia and some of its micro and macro implications. In contrast to other studies, I calculate markups from both value added and sales and empirically test whether some of the global trends in market power can be seen in Slovak firm level data as well. I find that the markups in Slovakia in fact declined since 2010, both in terms of value added and sales. Although the decrease in sales markups is negligible, the value added aggregate markup declined by 25% from 2.35 in 2012 to 1.78 in 2018. Value added markups tend to be higher for relatively value-added larger firms and they are also higher in larger sectors. Smaller firms (size indicated by number of employees) tend to have higher markups. It seems that a typical high markup firm is relatively small (in terms of number of employees) but produces relatively larger output. Correlations between markups and various measures of profitabality show that there is indeed a relationship between markups and market power. Markups strongly correlate with profits and they do not significantly react to changes in costs. Markups in Slovakia evolve in excess of marginal costs. Slovak firm data shows that markups are also inversely associated to labor shares. Correlation is statistically strong and empirically well established.
Intersectionality-Informed Sex/Gender-Sensitivity in Public Health Monitoring and Reporting (PHMR): A Case Study Assessing Stratification on an “Intersectional Gender-Score”

To date, PHMR has often relied on male/female stratification, but rarely considers the complex, intersecting social positions of men and women in describing the prevalence of health and disease. Stratification on an Intersectional Gender-Score (IG-Score), which is based on a variety of social covariables, would allow comparison of the prevalence of individuals who share the same complex intersectional profile (IG-Score). The cross-sectional case study was based on the German Socio-Economic Panel 2017 (n = 23,269 age 18+). After stratification, covariable-balance within the total sample and IG-Score-subgroups was assessed by standardized mean differences. Prevalence of self-rated health, mental distress, depression and hypertension was compared in men and women. In the IG-Score-subgroup with highest proportion of males and lowest probability of falling into the ‘woman’-category, most individuals were in full-time employment. The IG-Score-subgroup with highest proportion of women and highest probability of falling into the ‘woman’-category was characterized by part-time/occasional employment, housewife/-husband, and maternity/parental leave. Gender differences in prevalence of health indicators remained within the male-dominated IG-Score-subgroup, whereas the same prevalence of depression and self-rated health was observed for men and women constituting the female-dominated IG-Score-subgroup. These results might indicate that sex/gender differences of depression and self-rated health could be interpreted against the background of gender associated processes. In summary, the proposed procedure allows comparison of prevalence of health indicators conditional on men and women sharing the same complex intersectional profile.
An analysis of the cohomology structure of super Yang-Mills coupled to matter

Sets up the consistency conditions for super Yang-Mills coupled to the Wess-Zumino multiplet in the Wess-Zumino gauge with the auxiliary fields eliminated, after closing the algebra using the formulation of Batalin and Vilkovisky (1983). The resulting cohomology is then solved with the method of spectral sequences.
Multivariate Insurance Portfolio Risk Retention Using the Method of Multipliers

For an insurance company insuring multiple risks, capital allocation is an important practical problem. In the capital allocation problem, the insurance company must determine the amount of capital to assign to each policy or, equivalently, the amount of premium to be collected from each policy. Doing this relates to the problem of determining the risk retention parameters for each policy within the portfolio. In this article, the insurance risk retention problem of determining the optimal retention parameters is explored in a multivariate context. Given an underlying claims distribution and premium constraint, we are interested in finding the optimal amount of risk to retain or, equivalently, which level of risk retention parameters should be chosen by an insurance company. The risk retention parameter may be deductible (d), upper limit (u), or coinsurance (c). We present a numerical approach to solving the risk retention problem using the method of multipliers and illustrate how it can be implemented. In a case study, the minimum amount of premium to be collected is used as a constraint to the optimization and the upper limit is optimized for each policyholder. A Bayesian approach is taken for estimation of the parameters in a simple model involving regional effects and individual policyholder effects for the Wisconsin Local Government Property Insurance Fund (LGPIF) data, where the parameter estimation is performed in the R computing environment using the Stan library.
Numerical Investigation of the Thermohydraulic Performance of Double-Wave Cross-Corrugated Passages

A numerical study on flow and heat transfer in double-wave cross-corrugated passages with different structure parameters was conducted. The three-dimensional governing equations for mass, momentum, and heat transfer were solved using a control volume finite difference method and a validated low-Reynolds number k-ϵ model. The effects of Reynolds number and structure parameters, including pitch ratio (P1/P2) and height ratio (H1/H2), were studied. It was found that with a decrease in height ratio, the mainstream flow changed from a pattern dominated by L-shaped flow to one dominated by Z-shaped flow, whereas pitch ratio had almost no influence on the flow pattern. The average Nusselt number Nuav first increased and then decreased gradually with either an increase in the pitch ratio or a decrease in the height ratio. Pressure drop showed the same trend as heat transfer performance. The best performance evaluation criterion number (g) of double-wave passage was nearly 20% higher than that of the corresponding single-wave passage, whereas the worst was nearly 40% lower. On the whole, the double-wave plate with H1/H2 = 5 showed better overall performance. The double-wave plate with P1/P2 = 1 had better overall performance for Re < 5,000, whereas that with P1/P2 = 3 was better for Re > 7,500.
Optimal kernel shape and bandwidth for atomistic support of continuum stress

The treatment of atomistic scale interactions via molecular dynamics simulations has recently found favour for multiscale modelling within engineering. The estimation of stress at a continuum point on the atomistic scale requires a pre-defined kernel function. This kernel function derives the stress at a continuum point by averaging the contribution from atoms within a region surrounding the continuum point. This averaging volume, and therefore the associated stress at a continuum point, is highly dependent on the bandwidth and shape of the kernel. In this paper we propose an effective and entirely data-driven strategy for simultaneously computing the optimal shape and bandwidth for the kernel. We thoroughly evaluate our proposed approach on copper using three classical elasticity problems. Our evaluation yields three key findings: firstly, our technique can provide a physically meaningful estimation of kernel bandwidth; secondly, we show that a uniform kernel is preferred, thereby justifying the default selection of this kernel shape in future work; and thirdly, we can reliably estimate both of these attributes in a data-driven manner, obtaining values that lead to an accurate estimation of the stress at a continuum point.
Validation of γ‐radiation and their effect on phenolic compounds, antioxidant activity, and microbial load of fennel (Foeniculum vulgare) seeds and cinnamon (Cinnamomum verum) sticks

Abstract The aim of this study was to validate the optimum doses of γ‐radiation and its effect on the antioxidant capacity and microbial load of fennel seeds and cinnamon sticks. Gamma irradiation was applied in different doses 0.0, 2.5, 5.0, 7.5, 10, and 15 kGy. The findings stated that increasing gamma dose significantly (p < .05) increased the total phenolic content of the fennel seeds; however, it was decreased in cinnamon at doses higher than 5 kGy. The total flavonoid content was found higher after treatments at 5 kGy or more minor. After the gamma irradiation treatments, the antioxidant activities were enhanced. The microbial load of these spices was reduced after treatment. Doses more than 10.0 kGy are required to lower the bacterial load in samples, while only 5.0 kGy is sufficient to eliminate fungi growth. The partial least squares regression analysis stated the application of 7.5 kGy and reflects the most valid treatment doses for radiation treatments of fennel seeds and cinnamon sticks. Accordingly, it can be discovered that the γ‐radiation at a dose of 7.5 kGy could be considered a suitable dose for the preservation and decontamination of these spices and also for enhancing its antioxidant capacity. Three spices were subjected to gamma irradiation at different doses. The application of gamma radiation significantly reduces the level of the microbial load in the spices. Gamma irradiation improved the antioxidant capacity of the spices. Gamma irradiation can be applied as an effective preservative method in the food industries.
Ectopic dorsal root ganglion in cauda equina mimicking schwannoma in a child

Background: A heterotopic dorsal root ganglion (DRG) is sometimes observed in the vicinity of dysplastic neural structures during surgery for open spinal dysraphism; however, it is rarely associated with closed spinal dysraphism. Distinguish from neoplasms by preoperative imaging study is difficult. Although the embryopathogenesis of a heterotopic DRG has been speculated to be migration disorder of neural crest cells from primary neural tube, its details remain unelucidated. Case Description: We report a pediatric case with an ectopic DRG in cauda equina associated with a fatty terminal filum and bifid sacrum. The DRG mimicked a schwannoma in the cauda equina on preoperative magnetic resonance imaging. Laminotomy at L3 revealed that the tumor was entangled in the nerve roots, and small parts of the tumor were resected for biopsy. Histopathologically, the tumor consisted of ganglion cells and peripheral nerve fibers. Ki-67 immunopositive cells were observed at the periphery of the ganglion cells. These findings indicate the tumor comprised DRG tissue. Conclusion: We report detailed neuroradiological, intraoperative and histological findings and discuss the embryopathogenesis of the ectopic DRG. One should be aware of the possibility of ectopic or heterotopic DRGs when cauda equina tumors are observed in pediatric patients with neurulation disorders.
Brow and Eyelid Rejuvenation: Trends from the 100 Most Cited Articles over 30 Years

Background and Objective: Various periorbital rejuvenation techniques have been introduced over the last 3 decades. This study highlights important milestones in the evolution of periorbital rejuvenation surgery by identifying the 100 most-cited articles in this field. Material and Methods: The Web of Science citation index was used to identify the 100 most-cited articles concerning periorbital rejuvenation. Articles published in English from January 1989–April 2020 describing periorbital rejuvenation-related surgical techniques, facial aging, and anatomy were included. The terms “lower blepharoplasty”, “upper blepharoplasty”, “browlift”, “browplasty”, “endobrow lift”, “endoscopic brow”, “Foreheadplasty”, “lower eyelid anatomy”, “upper eyelid anatomy”, “forehead lift”, “eyelid rejuvenation”, “canthopexy”, “canthoplasty”, “eyelid fat pad”, “orbital fat pad”, “tear trough”, and “eyelid bags” were entered into the citation search. Web of Science Core Collection was the database used for the search. A manual review of the initial 159 studies was performed. Articles describing reconstructive or non-invasive techniques, injectable fillers, lasers, and neurotoxins were excluded. Of the 100 most-cited articles, the publication year, specialty journal, the corresponding author’s primary specialty, the focus of the article, the corresponding author’s country of residence, the type of study, and the level of evidence were analyzed. Results: The mean number of citations per article was 75 ± 42. There were more articles published from 1989–1999 (n = 53) than later decades. Most articles originated from the USA (n = 82) and were published in plastic surgery journals (n = 81). Plastic surgery was the primary specialty of the corresponding authors (n = 71), followed by oculoplastic surgery (n = 22). Most articles (n = 69) reported on surgical techniques. Of the clinical studies (n = 69), 45 (79%) provided level IV evidence. Conclusions: Of the 100 most-cited studies on periorbital rejuvenation, studies focusing on periorbital anatomy, aging, and surgical techniques comprised the most-cited publications. An anatomically based approach accounting for age-related changes in the periorbital structures is paramount in the field of contemporary periorbital rejuvenation.
Does Health-related Aid Really Matter? Evidence from South Asia

Using data from South Asia for the period 1990–2017, this paper examines the effectiveness of the health sector aid on infant mortality, neonatal mortality, child mortality and a new composite index of child mortality. The investigation of South Asia is interesting not only because it accounts for roughly one quarter of the world population and has attracted significant aid over the years but also because of the significant variations in health outcomes between countries in the region. Applying the instrumental variables method to account for the endogeneity of aid, we find that health-focused aid assists in improving child health outcomes in South Asian countries. The effect operates mainly through female literacy and is robust to a variety of specifications. Our findings have significant policy implications for achieving the post-MDG target and point to the importance of the health sector aid to improve child health for countries swamped with poorer health status. JEL Codes: F35, I15, O53