Miracle-dz/UniFAR-FTUs huggingface dataset:
Realization of high-Q Lamb wave resonator with smooth vertical etching profile for thin film lithium niobate

In this work, Lamb Wave Resonators (LWRs) based on 2 μm thin Y-cut LiNbO3 films have been fabricated using integrated fabrication process that defines IDTs (Inter Digital Transducers) on top surface and a partial Si cavity for a sacrificial layer on the bottom surface. We discuss the etch quality and its effects on the device's performance. For the first time, we present an optimized high-quality etched MEMS (Micro-electromechanical Systems) Resonator with smooth and vertical sidewalls on this material system, reporting the maximum Q-factor of 2500 at 846 MHz frequency. We observed that the resonator system has a Q-factor of 480 over the same frequency range when the etched surface has significant roughness and non-verticality. Q values of the device are greatly diminished by the presence of surface roughness and non-verticality of the etched edges. This truly highlights how important it is to have a high-quality etch profile for a piezoelectric material system like this so that the designed resonators can perform at their best.
Identification of a novel splice site mutation in the DNAAF4 gene of a Chinese patient with primary ciliary dyskinesia

Primary ciliary dyskinesia (PCD) is a rare hereditary orphan condition that results in variable phenotypes, including infertility. About 50 gene variants are reported in the scientific literature to cause PCD, and among them, dynein axonemal assembly factor 4 (DNAAF4) has been recently reported. DNAAF4 has been implicated in the preassembly of a multiunit dynein protein essential for the normal function of locomotory cilia as well as flagella. In the current study, a single patient belonging to a Chinese family was recruited, having been diagnosed with PCD and asthenoteratozoospermia. The affected individual was a 32-year-old male from a nonconsanguineous family. He also had abnormal spine structure and spinal cord bends at angles diagnosed with scoliosis. Medical reports, laboratory results, and imaging data were investigated. Whole-exome sequencing, Sanger sequencing, immunofluorescence analysis, hematoxylin-eosin staining, and in silico functional analysis, including protein modeling and docking studies, were used. The results identified DNAAF4 disease-related variants and confirmed their pathogenicity. Genetic analysis through whole-exome sequencing identified two pathogenic biallelic variants in the affected individual. The identified variants were a hemizygous splice site c.784-1G>A and heterozygous 20.1 Kb deletion at the DNAAF4 locus, resulting in a truncated and functionless DNAAF4 protein. Immunofluorescence analysis indicated that the inner dynein arm was not present in the sperm flagellum, and sperm morphological analysis revealed small sperm with twisted and curved flagella or lacking flagella. The current study found novel biallelic variants causing PCD and asthenoteratozoospermia, extending the range of DNAAF4 pathogenic variants in PCD and associated with the etiology of asthenoteratozoospermia. These findings will improve our understanding of the etiology of PCD.
Root locus analysis of a retarded quasipolynomial

Time delay systems (TDS), called hereditary or anisochronic as well, can be frequently found in many engineering problems and they constitute a widespread family of industrial plants. Modelling, identification, stability analysis, stabilization, control, etc. of TDS are challenging and fascinating tasks in modern systems and control theory as well as in academic and industrial applications. One of their possible linear representations in the form of the Laplace transform yields the transfer function expressed as a fraction of quasipolynomials, instead of polynomials, with delay (exponential) terms in denominators. In this contribution, detailed root location analysis of a characteristic retarded quasipolynomial of degree one is presented, which gives rise to the spectrum of a retarded TDS. The presented analysis represents also a powerful tool for controller tuning in pole-placement control algorithms for delayed systems. A simulation example clarifies the results obtained vie proven propositions, lemmas and theorems.
Successive Acanthamoeba Corneal Isolates Identified in Poland Monitored in Terms of In Vitro Dynamics

Background: Amoebae of the genus Acanthamoeba cause a sight-threatening infection called Acanthamoeba keratitis. It is considered a rare disease in humans but poses an increasing threat to public health worldwide, including in Poland. We present successive isolates from serious keratitis preliminary examined in terms of the identification and monitoring of, among others, the in vitro dynamics of the detected strains. Methods: Clinical and combined laboratory methods were applied; causative agents of the keratitis were identified at the cellular and molecular levels; isolates were cultivated in an axenic liquid medium and regularly monitored. Results: In a phase-contrast microscope, Acanthamoeba sp. cysts and live trophozoites from corneal samples and in vitro cultures were assessed on the cellular level. Some isolates that were tested at the molecular level were found to correspond to A. mauritanensis, A. culbertsoni, A. castellanii, genotype T4. There was variability in the amoebic strain dynamics; high viability was expressed as trofozoites’ long duration ability to intense multiply. Conclusions: Some strains from keratitis under diagnosis verification and dynamics assessment showed enough adaptive capability to grow in an axenic medium, allowing them to exhibit significant thermal tolerance. In vitro monitoring that was suitable for verifying in vivo examinations, in particular, was useful to detect the strong viability and pathogenic potential of successive Acanthamoeba strains with a long duration of high dynamics.
Comparison of density determination of liquid samples by density meters

Hydrostatic density determinations of liquids as reference material are mainly performed by National Metrology Institutes to provide means for calibrating or checking liquid density measuring instruments such as oscillation-type density meters. These density meters are used by most of the metrology institutes for their calibration and scientific work. The aim of this project was to compare the results of the liquid density determination by oscillating density meters of the participating laboratories. The results were linked to CCM.D.K-2 partly via Project EURAMET.M.D.K-2 (1019) "Comparison of liquid density standards" by hydrostatic weighing piloted by BEV in 2008. In this comparison pentadecane, water and of oil with a high viscosity were measured at atmospheric pressure using oscillation type density meter. The temperature range was from 15 °C to 40 °C. The measurement results were in some cases discrepant. Further studies, comparisons are essential to explore the capability and uncertainty of the density meters Main text To reach the main text of this paper, click on Final Report. Note that this text is that which appears in Appendix B of the BIPM key comparison database kcdb.bipm. org/. The final report has been peer-reviewed and approved for publication by the CCM, according to the provisions of the CIPM Mutual Recognition Arrangement (CIPM MRA).
A Low-Complexity Quantum Simulation Framework for Toeplitz-Structured Matrix and Its Application in Signal Processing

Toeplitz matrix reconstruction algorithms (TMRAs) are one of the central subroutines in array processing for wireless communication applications. The classical TMRAs have shown excellent accuracy in the spectral estimation for both uncorrelated and coherence sources in the recent era. However, TMRAs incorporate the classical eigenvalue decomposition technique for estimating the eigenvalues of the Toeplitz-structured covariance matrices that demand very high computational complexity for large arrays. We demonstrate a low-complexity quantum simulation framework exploiting the structured Hamiltonian of Toeplitz and circulant variants. In this framework, we consider two approaches for the estimation of the eigenvalue spectrum of a given Toeplitz-structured matrix: first, an analytical framework with Jordan form-based sparse-decomposition of a dense-Toeplitz matrix, and second, an approximation method for the conversion of a Toeplitz matrix into a circulant matrix embedding quantum subroutines. We have also compared the efficacy of the proposed algorithms with standard Hamiltonian simulation and quantum phase estimation techniques for different quantum time resolutions and gate complexities. We show quantum gate-complexity analysis for our proposed algorithms. Considering the large dimensions of the Toeplitz matrix, we have employed random matrix theory in deriving the error bounds for the estimated eigenvalues. The numerical results are obtained partly in a classical computer and in an IBM quantum simulator.
Adaptive Fuzzy Control for Heterogeneous Vehicular Platoon Systems With Collision Avoidance and Connectivity Preservation

This article investigates the problem of fuzzy adaptive asymptotic tracking control for a third-order heterogeneous vehicular platoon system with input saturation. The unknown nonlinear functions are approximated using fuzzy logic systems. To address the issue of input saturation, a control scheme with an auxiliary design system is proposed. A spacing error is created to reduce the intervehicle spacing. The proposed adaptive asymptotic tracking control design scheme employs the barrier Lyapunov functions to impose distance restrictions, ensuring collision avoidance, and maintaining communication connections. The scheme guarantees asymptotic convergence with zero spacing error and proves the individual and string stability of the entire heterogeneous vehicular platoon. Simulations are conducted to demonstrate the effectiveness of the proposed results.
Alpha-Tocopherol Significantly Improved Squalene Production Yield of Aurantiochytrium sp. TWZ-97 through Lowering ROS levels and Up-Regulating Key Genes of Central Carbon Metabolism Pathways

Media supplementation has proven to be an effective technique for improving byproduct yield during microbial fermentation. This study explored the impact of different concentrations of bioactive compounds, namely alpha-tocopherol, mannitol, melatonin, sesamol, ascorbic acid, and biotin, on the Aurantiochytrium sp. TWZ-97 culture. Our investigation revealed that alpha-tocopherol was the most effective compound in reducing the reactive oxygen species (ROS) burden, both directly and indirectly. Adding 0.7 g/L of alpha-tocopherol led to an 18% improvement in biomass, from 6.29 g/L to 7.42 g/L. Moreover, the squalene concentration increased from 129.8 mg/L to 240.2 mg/L, indicating an 85% improvement, while the squalene yield increased by 63.2%, from 19.82 mg/g to 32.4 mg/g. Additionally, our comparative transcriptomics analysis suggested that several genes involved in glycolysis, pentose phosphate pathway, TCA cycle, and MVA pathway were overexpressed following alpha-tocopherol supplementation. The alpha-tocopherol supplementation also lowered ROS levels by binding directly to ROS generated in the fermentation medium and indirectly by stimulating genes that encode antioxidative enzymes, thereby decreasing the ROS burden. Our findings suggest that alpha-tocopherol supplementation can be an effective method for improving squalene production in Aurantiochytrium sp. TWZ-97 culture.
Engineered Synthetic STxB for Enhanced Cytosolic Delivery

Many molecular targets for cancer therapy are located in the cytosol. Therapeutic macromolecules are generally not able to spontaneously translocate across membranes to reach these cytosolic targets. Therefore a strong need exists for tools that enhance cytosolic delivery. Shiga toxin B-subunit (STxB) is used to deliver therapeutic principles to disease-relevant cells that express its receptor, the glycolipid Gb3. Based on its naturally existing membrane translocation capacity, STxB delivers antigens to the cytosol of Gb3-positive dendritic cells, leading to the induction of CD8+ T cells. Here, we have explored the possibility of further increasing the membrane translocation of STxB to enable other therapeutic applications. For this, our capacity to synthesize STxB chemically was exploited to introduce unnatural amino acids at different positions of the protein. These were then functionalized with hydrophobic entities to locally destabilize endosomal membranes. Intracellular trafficking of these functionalized STxB was measured by confocal microscopy and their cytosolic arrival with a recently developed highly robust, sensitive, and quantitative translocation assay. From different types of hydrophobic moieties that were linked to STxB, the most efficient configuration was determined. STxB translocation was increased by a factor of 2.5, paving the path for new biomedical opportunities.
Surface Cracks Length Calculation in Segmented Images using Image Processing Techniques

Civil infrastructure systems make up a large share of global assets. Hence, frequent crack inspection is crucial in maintaining infrastructures. The conventional methods of examining surface cracks are time-consuming and subjective. However, the vision-based component of unmanned aerial vehicles draws an advantage in replacing the traditional laborious approach. The alternative approach for crack inspection is automation by image processing techniques. This paper introduces a method to calculate the length of surface cracks. The segmented images are the outcomes of semantic segmentation prediction models. The authors developed a software application that allows end-users to provide endpoints of the crack, and the application will calculate this crack segment instantaneously. The introduced algorithm yielded an average error of 4.26 mm and 3.17 mm from the two gathered datasets. The experimental results proved that the developed image processing algorithm for surface crack length measurement could calculate actual surface crack with tolerable errors.
Weighted inequalities for the Riesz potential on the sphere

ABSTRACT We prove a version of the Stein–Weiss inequality for the Riesz potential of the conformal Laplacian on the sphere. Moreover, we show that the result can be improved for functions invariant under the action of the group . This last result will be a consequence of a more general one for ultraspherical expansions.
Data based models: an automatic method for model structure determination

A technique for automatically determining the structure of linear discrete-time models from real data is briefly illustrated. For pole-placement control system design, as shown in an example, it is essential that near, or exact, pole-zero cancellations should not occur within the model. It has been found that the Young's information criterion (YIC) statistic has consistently identified model structures that are free from such cancellations, and that subsequently result in good control system performance. Naturally, some control system design algorithms, for example predictive controllers, are insensitive to overparameterised models; however the YIC statistic is still useful, as it normally indicates the simplest model structure, which should result in minimum complexity controllers being designed.
Improving Rhamnolipids Biosynthesis in Pseudomonas sp. L01 through Atmospheric and Room-Temperature Plasma (ARTP) Mutagenesis

Biosurfactants have significant applications in various industries, including microbial-enhanced oil recovery (MEOR). While the state-of-the-art genetic approaches can generate high-yield strains for biosurfactant production in fermenters, there remains a critical challenge in enhancing biosurfactant-producing strains for use in natural environments with minimal ecological risks. The objectives of this work are enhancing the strain’s capacity for rhamnolipids production and exploring the genetic mechanisms for its improvement. In this study, we employed atmospheric and room-temperature plasma (ARTP) mutagenesis to enhance the biosynthesis of rhamnolipids in Pseudomonas sp. L01, a biosurfactant-producing strain isolated from petroleum-contaminated soil. Following ARTP treatment, we identified 13 high-yield mutants, with the highest yield of 3.45 ± 0.09 g/L, representing a 2.7-fold increase compared to the parent strain. To determine the genetic mechanisms behind the enhanced rhamnolipids biosynthesis, we sequenced the genomes of the strain L01 and five high-yield mutants. A comparative genomic analysis suggested that mutations in genes related to the synthesis of lipopolysaccharides (LPS) and the transport of rhamnolipids may contribute to the improved biosynthesis. To the best of our knowledge, this is the first instance of utilizing the ARTP approach to improve rhamnolipid production in Pseudomonas strains. Our study provides valuable insights into the enhancement of biosurfactant-producing strains and the regulatory mechanisms of rhamnolipids biosynthesis.
A single-sided homogeneous Green's function representation for holographic imaging, inverse scattering, time-reversal acoustics and interferometric Green's function retrieval

Green's theorem plays a fundamental role in a diverse range of wavefield imaging applications, such as holographic imaging, inverse scattering, time-reversal acoustics and interferometric Green's function retrieval. In many of those applications, the homogeneous Green's function (i.e. the Green's function of the wave equation without a singularity on the right-hand side) is represented by a closed boundary integral. In practical applications, sources and/or receivers are usually present only on an open surface, which implies that a significant part of the closed boundary integral is by necessity ignored. Here we derive a homogeneous Green's function representation for the common situation that sources and/or receivers are present on an open surface only. We modify the integrand in such a way that it vanishes on the part of the boundary where no sources and receivers are present. As a consequence, the remaining integral along the open surface is an accurate single-sided representation of the homogeneous Green's function. This single-sided representation accounts for all orders of multiple scattering. The new representation significantly improves the aforementioned wavefield imaging applications, particularly in situations where the first-order scattering approximation breaks down.
Automatic pattern localization across layout database and photolithography mask

Advanced process photolithography masks require more and more controls for registration versus design and critical dimension uniformity (CDU). The distribution of the measurement points should be distributed all over the whole mask and may be denser in areas critical to wafer overlay requirements. This means that some, if not many, of theses controls should be made inside the customer die and may use non-dedicated patterns. It is then mandatory to access the original layout database to select patterns for the metrology process. Finding hundreds of relevant patterns in a database containing billions of polygons may be possible, but in addition, it is mandatory to create the complete metrology job fast and reliable. Combining, on one hand, a software expertise in mask databases processing and, on the other hand, advanced skills in control and registration equipment, we have developed a Mask Dataprep Station able to select an appropriate number of measurement targets and their positions in a huge database and automatically create measurement jobs on the corresponding area on the mask for the registration metrology system. In addition, the required design clips are generated from the database in order to perform the rendering procedure on the metrology system. This new methodology has been validated on real production line for the most advanced process. This paper presents the main challenges that we have faced, as well as some results on the global performances.
Analysis of Service Quality, Promotion, and Facilities on Customer Satisfaction

Consumer satisfaction has an important role as a determinant for the success and development of a culinary company. So, the company must be able to make consumers feel satisfied and become loyal customers. There are several influencing factors, namely regarding the quality of service, promotion, and facilities that must be provided. This study aims to analyze the influence of the variables of service quality, promotion, and facilities on customer satisfaction. This study uses a quantitative research method, in which this method uses measurement tools or applications to obtain statistical values. The research population is customers who have visited the Ayam Penyet Cindelaras Rantauperapat Restaurant. The data that has been collected and obtained from the results of this study is then calculated using the smart plus 4 applications. From the results of the calculations that have been obtained, it is concluded that all outer loading values for each indicator are declared valid because they meet the standard or have an AVE value greater than 0.5 (> 0.5). latent variable consumer satisfaction has a good R Square value because it has a value greater than 0.75. Therefore, it can be concluded that the diversity of service quality variables, promotions, and facilities can affect the consumer satisfaction variable by 93%.
The Association between Music and Language in Children: A State-of-the-Art Review

Music and language are two complex systems that specifically characterize the human communication toolkit. There has been a heated debate in the literature on whether music was an evolutionary precursor to language or a byproduct of cognitive faculties that developed to support language. The present review of existing literature about the relationship between music and language highlights that music plays a critical role in language development in early life. Our findings revealed that musical properties, such as rhythm and melody, could affect language acquisition in semantic processing and grammar, including syntactic aspects and phonological awareness. Overall, the results of the current review shed further light on the complex mechanisms involving the music-language link, highlighting that music plays a central role in the comprehension of language development from the early stages of life.
Emergence Of Nonlinear Dynamics In 3D CavityMixing Of Linear Fluids

The emergence of nonlinear dynamics in cavity mixing is examined using the BEM. The formulation is implemented for the simulation of 3D transient creeping flows of Newtonian and linear viscoelastic fluids of the Oldroyd-B type. A boundary-only formulation in the time domain is proposed for viscoelastic flows. It is found that, for simple cavity flow induced by a rotating vane at constant angular velocity, the traction at the vane tip and cavity face exhibits nonlinear periodic dynamical behavior with time for fluids obeying linear constitutive equations.