Miracle-dz/UniFAR-FTUs huggingface dataset:
LIPID PEROXIDATION AND PROTEIN OXIDATION INDUCED BY DIFFERENT NANOPARTICLES IN ZEBRAFISH ORGANS

The protein oxidation and the lipid peroxidation induced by the presence of five different kinds of nanoparticles were determined in different tissues of zebrafish (Danio rerio). Both oxidative stress markers showed to be dose-dependent. At 1 ppm nanoparticle concentration, the five assayed nanoparticles showed higher protein oxidation than the control experiments. Europium-doped yttrium oxide (Y2O3:Eu) and carboxylated multi-walled carbon nanotubes (MWCNT-COOH) showed the highest effect, especially in ovaries, testicles and brain, reaching carbonyl content in proteins up to 4-times higher than control, while bismuth germanate (BGO) and MWCNT-COOH nanoparticles induced lipid peroxidation in all analyzed tissues, reaching values up to two-times higher than those from non-exposed control fish. BGO and silver nanoparticles (AgNP) showed less oxidative effect; nevertheless, the protein oxidation still accounted for up to 3-times the control fish values. At 1 ppm, the protein oxidation induced by some nanoparticles reached the values obtained in the experiments with 100 μM H2O2. On the other hand, no significant differences were found in gene expression of oxidative stress markers after 48 h treatment. The results from this work clearly indicate that exposure to those nanoparticles may cause significant protein and lipid oxidative damage.
A Divide-and-Conquer Approach for Visual Odometry with Minimally-Overlapped Multi-Camera Setup

Pose estimation of a moving camera rig from the images alone has been investigated by the computer vision community for decades, because the location and direction information of the cameras are the basis for more advanced applications, such as 3D reconstruction and Simultaneous Localization and Mapping (SLAM). Visual Odometry (VO) is the accumulation of the relative pose estimation while the camera rig moves. There are some visual odometry methods for mono view, stereo, omnidirectional and multi-cameras that require additional sensor input(odometry, compass, e.g,) and/or synchronized cameras. However, in our Virtual Exercise Environment (VEE) system, and other low-cost multi-camera setups, none of the above methods can be applied. The Bundle Adjustment(BA) is the general approach for a non-regular case like the VEE system. BA puts all the known variables in one huge matrix and solves the unknowns at once with Levenberg-Marquardt iterations. Thus, the BA is computationally expensive in nature with the complexity of O ( n 3 ), and sometimes infeasible. In this thesis, I propose a `divide and conquer' approach that generates additional observations from consecutive images in neighboring camera pairs. I show this approach to solve the critical condition and drastically speed up pose estimation when compared to BA. The performance with different conditions and sub-algorithms are also tested and discussed.
Response to the reviewers ’ comments

For the purpose of convenience, we summarize overall organization of the paper as follows. • In Section 1, we introduce the background knowledge on wireless sensor network applications and the problem of 3D RSS-AoA localization. • In Section 2, we describe the system characteristics and the formulation of the localization problem in terms of hybrid measurement perspective. • In Section 3, we propose a hybrid localization solution. A step-by-step procedure consisting of relate parameter calculation and target estimation is introduced. • In Section 4, we discuss analytical and numerical simulation results for the proposed scheme and other conventional approaches. • In Section 5, we provide conclusions and future directions. In summary, the following major changes have been made in the revised manuscript. 1. Following Reply 2.2 and 3.5, we added more texts in Introduction section. 2. Following Reply 1.1 and 3.1, we expanded the discussion on the related works. 3. More descriptions and discussions have been included in the Simulation Results section following Reply 1.2 and 3.23. 4. Related works have been accordingly updated in the References section. 5. Typos and the grammar mistakes have been corrected throughout the entire manuscript.
UC Office of the President Recent Work Title Silicon Integrated High-Density Electrocortical Interfaces Permalink

| Recent demand and initiatives in brain research have driven significant interest toward developing chronically implantable neural interface systems with high spatiotemporal resolution and spatial coverage extending to the whole brain. Electroencephalography-based systems are noninvasive and cost efficient in monitoring neural activity across the brain, but suffer from fundamental limitations in spatiotemporal resolution. On the other hand, neural spike and local field potential (LFP) monitoring with penetrating electrodes offer higher resolution, but are highly invasive and inadequate for long-term use in humans due to unreliability in long-term data recording and risk for infection and inflammation. Alternatively, electrocorticography (ECoG) promises a minimally invasive, chronically implantable neural interface with resolution and spatial coverage capabilities that, with future technology scaling, may meet the needs of recently proposed brain initiatives. In this paper, we discuss the challenges and state-of-the-art technologies that are enabling next-generation fully implantable high-density ECoG interfaces, including details on electrodes, data acquisition frontends, stimulation drivers, and circuits and antennas for wireless communications and power delivery. Along with state-of-the-art implantable ECoG interface systems, we introduce a modular ECoG system concept based on a fully encapsulated neural interfacing acquisition chip (ENIAC). Multiple ENIACs can be placed across the cortical surface, enabling dense coverage over wide area with high spatiotemporal resolution. The circuit and system level details of ENIAC are presented, along with measurement results.
Emission Inventory Of The Main NaturalMethane Sources In A Mediterranean Area

A natural emission inventory of methane (CH4), one of the main greenhouse gases, was carried out in the frame of the ESCOMPTE project. The algorithms used for calculation are mainly based on the CORINAIR [1] and the IPCC methodology [2]. Methane emission is estimated for the year 1999 at 10.3Tg in the ESCOMPTE area which represents one of the main natural sources of emissions with dimethylsulfide (DMS) from the sea, carbon dioxide (CO2) from forest fires, and the Non Methanic Volatile Organic Compounds from vegetation. Natural methane emissions, around 43% of the total CH4 emission, are dominated mainly by the animals and wetlands contribution. They are located in the west of the area. Soils constitute a sink (about 1Tg) that does not compensate the emissions. Despite the important amount of data collected, additional information would be needed to determine a more detailed evolution of emissions throughout the year.
Title Differential roles of cyclin-dependent kinase 5 in tangential and radial migration of cerebellar granule cells

The cerebellar granule cell is a unique neuron which undergoes tangential migration along axonal tracts and radial migration along glial fibers sequentially during postnatal development. Little is known about molecular bases of the differential kinetics of tangential and radial migration. Here we developed a time-lapse imaging assay for tangential migration of cerebellar granule cells, and investigated comparative contributions of cyclin-dependent kinase 5 (CDK5), a key regulator of neuronal migration, in tangential and radial migration of granule cells in vivo and in organotypic cultures. Overexpression of a dominant-negative form of CDK5 severely disrupted cell morphology and somal movement during radial migration, while it only moderately affected tangential migration. Dominant-negative inhibition of CDK5 induced formation of ectopic radial processes in granule cells in vivo which aberrantly elongated into the white matter in the cerebellum. Live imaging of granule cell migration in cerebellar slices revealed that CDK5 regulates not only nuclear migration but also centrosome movement during radial migration. These findings suggest a mode-specific function of CDK5 in neuronal migration.
Interactive comment on “ New cloud chamber experiments on the heterogeneous ice nucleation ability of oxalic acid in the immersion mode ” by R

COMMENT: I recommend the manuscript for publication after some adjustments have been taken into account. In its current form the manuscript is drafted in a manner that many at times suggests that the goal of the study was to compare and contrast their work to that of Zobrist et al. [2006]. While this is a useful comparison, it should not appear like this is the goal of the paper. The manuscript is also quite long. I understand the reason for this given that all details of the experimental set up, results
A parametrization of the geometry of sea straits

A parametrization of the bottom topography of sea straits is proposed, which leads to a simple relation between severa! strait parameters and other properties pertaining to the whole sea. Two different examples of the usefulness of this relation are given: (1) the net water deftcit, i. e. evaporation minus precipitation and runoff, from the whole sea is estimated from strait parameters alone; and (2) the salinity difference at the strait of Tiran in the Pleistocene is estimated to have been ftve times greater than at present.
Neobisium simile (L. Koch, 1873) (Pseudoscorpiones: Neobisiidae): a species new to Britain

Abstract Specimens of a Neobisium (Pseudoscorpiones: Neobisiidae) were collected from Craig yr Aber woods, Bridgend, Wales, in November 2017. Using morphological characters and DNA barcoding of the cytochrome c oxidase subunit I gene they were identified as N. simile (L. Koch, 1873), a species new to Britain. Molecular comparison with other Neobisium specimens confirms N. simile as the most similar species (88% similarity) with which it forms a single clade, although the degree of dissimilarity could suggest an unrecognized sibling species. A detailed morphological description of N. simile from Craig yr Aber is provided, along with the DNA barcode, in view of the potential for future taxonomic revision. A probable record of N. simile from Wales in 1984 is discussed. Knowledge of the distribution and ecology of N. simile is summarized. The Welsh population of N. simile was probably introduced from the Pyrenees or south-western France, possibly with imports of raw materials for the steel industry. British pseudoscorpion workers should be vigilant for N. simile, though it may be restricted to South Wales.
Comments and Corrections

Recently, Cheng and Jiang [IEEE Commun. Lett. , vol. 15, no. 11, pp. 1228-1230, 2011] proposed a novel homomorphic message authentication code (MAC) scheme, called TraceMac, for authentication in network coding, which is based on the trace function over a finite field, and claimed to achieve a reliable security of 1/ql, where q is the cardinality of the message symbol field Fq , and l ∈ Z+ is a proper security parameter. A formal proof of its security is also given in their work. However, in this letter, we show that there exists an inherent vulnerability in Cheng-Jiang TraceMac scheme, which results in a forgery attack on the scheme. Moreover, we also point out an error in their formal security proof. We hope that with our discussion, a better understanding of using trace function to design homomorphic MAC scheme can be identified, and similar mistakes can be avoided in future design and security proof of homomorphic MAC scheme for network coding.
International Knowledge Flows: Evidence from an Inventor-Firm Matched Data Set

We describe the construction of a panel data set from the U.S. patent data that contains measures of inventors' life-cycle RD the fraction of research-active U.S. residents with foreign research experience appears to be falling, suggesting that U.S. pharmaceutical and semiconductor firms are increasingly locating operations in foreign countries to employ such researchers, as opposed to such researchers immigrating to the U.S. to work. In addition, we investigate which U.S. firms conducting R&D build upon innovations originating abroad. We find that employing or collaborating with researchers who have research experience abroad seems to facilitate the use of output of non-U.S. R&D. We also find that in the semiconductor industry smaller and older firms, and in the pharmaceutical industry, younger firms are more likely to access foreign R&D output.
An Outdoor Stereo Camera System for the Generation of Real-World Benchmark Datasets with Ground Truth

In this report we describe a high-performance stereo camera system to capture image sequences with high temporal and spatial resolution for the evaluation of various image processing tasks. The system was primarily designed for complex outdoor and traffic scenes which frequently occur in the automotive industry, but is also suited for other applications. For this task the system is equipped with a very accurate inertial measurement unit and global positioning system, which provides exact camera movement and position data. The system is already in active use and has produced several terabyte of challenging image sequences which are available for download.
The 12 th International Conference on Fluidization-New Horizons in Fluidization Engineering Engineering Conferences International Year 2007 Simulation of a Pulsating Bed Using Eulerian Approach

A numerical study of the effect of gas pulsation on the flow pattern of solid particles in a two-dimensional gas-solid fluidized bed was conducted using the Eulerian granular kinetic theory. Our simulated bed dynamics agreed well with the experimental work of Koksal and Vural, and with the Discrete Element Method (DEM) model simulations of Tsuji et al. INTRODUCTION Gas-solid fluidized beds are widely used in many industrial processes. One operation in which the gas velocity oscillates analogous to a vibrating bed is called pulsating fluidization. The pulsating fluidized bed was first used to fluidize cohesive particles and served as a method of eliminating slugs and gas channeling, thus improving the quality of fluidization. Koksal and Vural [1] recently applied pulsation to the fluidized beds of coarse particles, and suggested that the size of the bubbles in the fluidized bed can be controlled by the gas pulsation. Their study also revealed that pulsation produced more uniform fluidization with less bed expansion, thereby improving the gas-solid contact in comparison with continuous flow. Wong and Baird’s [2] investigation also showed that pulsation gas flow results in smaller and more uniform bubbles than continuous gas flow. Tsuji et al. [3] developed numerical simulation of pulsating fluidized beds using the Discrete Element Method (DEM). In this work we studied numerical simulations of pulsating fluidized beds using the Eulerian granular kinetic theory model and Fluent 6.1 computational fluid dynamics (CFD) code. Our numerical simulations predicted the dynamics of the bed reasonably well when compared to the Koksal and Vural [1] experimental results and the DEM simulations of Tsuji et al. [3].
Comparative Measurements of Underwater Irradiance in Illuminance, Quanta and Energy in Lake Biwa

Underwater irradiances were measured in Lake Biwa in terms of lux, quanta (400-700 nm) and total energy in the shortwave range (300-2500 nm). The attenuation of irradiance was most rapid in energy, least in illuminance and in-between in quanta. Similar results were obtained from computations using the spectral sensitivity of sensors in conjunction with the earlier reported measurements of underwater spectral irradiance obtained for Lake Biwa. Thus, the differential attenuation of irradiance among these three expressions is due to the differences in the spectral sensitivity among the sensors together with characteristics of Lake Biwa regarding the selective absorption of spectral irradiance. Computed results also indicated that the penetration of energy flux in the range of 400-700 nm was virtually equal to that of photon flux. Analysis and discussion are extended to other lakes and marine environments reported in the literature. The significant deviations of underwater irradiance in lux from irradiance as photon flux density underscores the importance of using quanta or energy measurements in the photosynthetically active wavelength range in studies of primary production in aquatic habitats.
PROVOCATION SERIES PAPERS : HRM IN THE 21 ST CENTURY Becoming an evidence-based HR practitioner

Evidence-based HR (EBHR) is a decision-making process combining critical thinking with use of the best available scientific evidence and business information. We describe how to get started as an evidencebased HR practitioner. Actively managing professional decisions is a key aspect of EBHR. Doing so involves making decisions, especially consequential or recurring ones, using practices supported by high-quality research. We present a step-by-step set of approaches to becoming an evidence-based HR practitioner: from getting started, through everyday practices and continuous learning to integrating EBHR into your organisation. In offering guidance for evidence-based practice, this article underscores the connection between effective practice and organisational research. Contact: Denise M. Rousseau, Carnegie Mellon University, 5000 Forbes Avenue, Pittsburgh, PA 15213-3890, USA. Email: denise@cmu. eduhrmj_173 221.235
GAMPACK (GPU Accelerated Algebraic Multigrid Package)

In reservoir simulation, the elliptic character of the pressure subsystem and the inhomogeneous permeability field result in extremely slow convergence for conventional iterative solvers. Algebraic multigrid (AMG) methods address this challenge by constructing a multilevel hierarchy of matrices that naturally adapts to the permeability channels of the underlying geology. Preconditioning with AMG allows difficult cases with millions of unknowns to be solved in just a few iterations. In just a few years, graphical processing units (GPUs) have progressed from a research curiosity to a productivity workhorse by reducing time-to-solution and overall hardware cost. The highly irregular computation patterns of AMG, however, require new approaches to adapt to the many-core paradigm. The construction of the coarse matrix hierarchy and grid transfer operators poses a particular challenge for GPU acceleration. We show that by carefully selecting algorithms with sufficient fine-grained parallelism, and implementing them with novel approaches, it is possible to substantially accelerate both the setup and solve stages. We present GAMPACK, a library for accelerated AMG, and show that on a single GPU it can typically reduce the total setup and solve time by a factor of over 5, when compared to a widely-used AMG solver running on 8 Xeon cores.
Comparing Low-Pain and No-Pain Multicore Haskells

Multicore and NUMA architectures are becoming the dominant processor technology and functional languages are theoretically well suited to exploit them. In practice, however, implementing eective high level parallel functional languages is extremely challenging. This paper is a systematic programming and performance comparison of four paral- lel Haskell implementations on a common multicore architecture. It provides a detailed analysis of the performance, and contrasts the programming eort that each language requires with the parallel performance delivered. The study uses 15 'typical' programs to compare a 'no pain', i.e. entirely implicit, parallel implementation with three 'low pain', i.e. semi-explicit, language implementations. We report detailed studies comparing the parallel performance delivered. The com- parative performance metric is speedup which normalises against sequential perfor- mance. We ground the speedup comparisons by reporting both sequential and parallel runtimes and eciencies for three of the languages. To measure the programming eort required by each language we record the number of programs improved and the relative and absolute program changes required to coordinate the parallelism. The results of the study are encouraging and, on occasion, surprising. We find that fully implicit parallelism as implemented in FDIP cannot yet compete with semi- explicit parallel approaches. Semi-explicit parallelism shows encouraging speedup for many of the programs in the test suite. Languages with implementations designed for distributed memory architectures perform surprisingly well given their high message- passing costs. This leads us to speculate that, as the number of cores grow, imple- mentations with some form of independent heap will outperform those with shared heaps.
Simulation and prediction of ecological bearing capacity based on system dynamics in urbanization process of Dalian City

Urbanization process will make threat to city ecological bearing capacity.According to system dynamics principle,the ecological bearing capacity dynamic simulation model has been constructed to predict the ecological carrying capacity during the urbanization process in Dalian.The model is constructed based on the detailed analysis to the systematic characteristics of urbanization process and the complex relationship between the factors in the urbanization system.The predicted results indicate that urbanization will strongly threaten the ecological environment.In 2015 and 2020,the usage degree index of water resource,land resource and COD are all greater than 1,beyond the regional ecological bearing capacity of Dalian city,especially COD,respectively 4.24 and 4.43,the next is water resources,respectively 1.67 and1.81,the last is land,respectively 1.15 and 1.75. In the year of 2015 and 2020,the ecological bearing capacity composite index of Dalian city will reach 4.25 and 4.95,and the contradictions between long-term exploitation intensity and ecological bearing capacity will deteriorate.
Validation of the Ceredigion Youth Screening Tool

Evidence suggests that only a small minority of youth offenders will continue their behaviour in the longer term and largely independent of any interventions they may receive (Bateman, 2011; Haines & Case, 2015). Hence, “screening out” this larger low-risk cohort could have a positive impact upon the individual through a reduction in stigmatisation/labelling and free up resources for higher risk clients. This article outlines development of the Ceredigion Youth Screening Tool (CYSTEM)—developed and tested to address the two facets of criminality and vulnerability—closely aligned to the eight key risk indicators identified in the Risk-Needs-Responsivity (R-N-R) literature (Andrews & Bonta, 2010). Initial results with two cohorts of 372 young people indicate good convergent and discriminative validity in screening out the lowest level referrals, while also identifying 90% of potential future offenders. More importantly, CYSTEM is able to screen out approximately 35% of the low-risk offenders that are unlikely to require formal evaluation and/or intervention. It is suggested that the streamlining of this process using CYSTEM reduces demand on staff time and decreases the stigmatisation of young people referred for minor offences. Potential improvements to the tool and future developments in statistical risk prediction are also discussed.