Miracle-dz/UniFAR-FTUs huggingface dataset:
Dissociation of Madin-Darby canine kidney epithelial cells by the monoclonal antibody anti-arc-1: mechanistic aspects and identification of the antigen as a component related to uvomorulin

It has previously been shown that the monoclonal antibody anti-Arc-1 dissociates Madin-Darby canine kidney (MDCK) epithelial cells and changes their morphology in vitro (Imhof, B.A., H.P. Vollmers, S.L. Goodman, and W. Birchmeier, 1983, Cell, 35:667-675). In this article we demonstrate that the anti-Arc-1 antibody recognizes an uvomorulin-like molecule on MDCK cells, i.e., it immunoprecipitates an 84-kD protein fragment from a tryptic digest of cell surfaces in the presence of Ca2+ (as does anti-uvomorulin antiserum). Furthermore, anti-uvomorulin antiserum prevents the binding of anti-Arc-1 to MDCK cells. The distribution of the Arc-1 antigen is also quite similar to that of uvomorulin: it is enriched at the cell-cell contacts both of MDCK cells and of cells in various canine tissues. In the intestinal epithelium the antigen could be further localized in the region of the junctional complex. To study the mechanism of action of the dissociating antibody, MDCK cells grown on Nuclepore filters in Boyden chambers were exposed to anti-Arc-1 from either the upper or lower compartment. It could be shown that the antibody interfered with cell adhesion only from the basolateral but not from the apical cell surface. Antibody action was inhibited in the presence of colchicine but not cytochalasin B. Furthermore, cell dissociation was prevented when the cellular cAMP level was raised. These findings indicate that the anti-Arc-1 antibody acts on a target below the tight junctions (possibly on the antigen located in the junctional complex), and they confirm that cytoskeleton and metabolic factors are actively involved in the maintenance of junctional integrity.
Chemical Leaching of Metals from Wastewater Sludge: Comparative Study by Use of Three Oxidizing Agents [H 2O 2, FeCl 3, and Fe 2(SO 4) 3]

Chemical leaching of the toxic metals (cadmium, chromium, copper, nickel, lead, and zinc) and behavior of other elements (aluminum, calcium, iron, potassium, magnesium, manganese, sodium, phosphorus, and sulfur) in the wastewater sludge of the Montreal Urban Community wastewater treatment plant (Montreal, Quebec, Canada) were studied in 2‐L beakers using sulfuric acid and three oxidants [H 2O 2, FeCl 3, and Fe 2(SO 4) 3] and their association. Metal removal efficiencies of these oxidants were evaluated under different conditions of pH (2.0 and 2.5) and oxidation‐reduction potential (ORP) (350 to 500 mV). The solubilization of the different elements was linked to pH and/or ORP, and a period of 2 to 4 hours was required to obtain satisfactory metals removal yields. Sludge‐fertilizing properties generally were little affected by the decontamination process, especially for processes using a ferric salt. Finally, optimal conditions, for best metals solubilization, were established at pH 2.5 and ORP = 450 mV in a 4‐hour period.
Personality, Driving Behavior and Mental Disorders Factors as Predictors of Road Traffic Accidents Based on Logistic Regression

Background: The aim of this study was to evaluate the effect of variables such as personality traits, driving behavior and mental illness on road traffic accidents among the drivers with accidents and those without road crash. Methods: In this cohort study, 800 bus and truck drivers were recruited. Participants were selected among drivers who referred to Imam Sajjad Hospital (Tehran, Iran) during 2013-2015. The Manchester driving behavior questionnaire (MDBQ), big five personality test (NEO personality inventory) and semi-structured interview (schizophrenia and affective disorders scale) were used. After two years, we surveyed all accidents due to human factors that involved the recruited drivers. The data were analyzed using the SPSS software by performing the descriptive statistics, t-test, and multiple logistic regression analysis methods. P values less than 0.05 were considered statistically significant. Results: In terms of controlling the effective and demographic variables, the findings revealed significant differences between the two groups of drivers that were and were not involved in road accidents. In addition, it was found that depression and anxiety could increase the odds ratio (OR) of road accidents by 2.4- and 2.7-folds, respectively (P=0.04, P=0.004). It is noteworthy to mention that neuroticism alone can increase the odds of road accidents by 1.1-fold (P=0.009), but other personality factors did not have a significant effect on the equation. Conclusion: The results revealed that some mental disorders affect the incidence of road collisions. Considering the importance and sensitivity of driving behavior, it is necessary to evaluate multiple psychological factors influencing drivers before and after receiving or renewing their driver’s license.
Endoscopic nasobiliary drainage improves jaundice attack symptoms in benign recurrent intrahepatic cholestasis: A case report

A 66-year-old male with unbearable pruritus and jaundice was admitted for detailed examination. Blood tests on admission showed increased bilirubin with a dominant direct fraction. Ultrasonography and computed tomography performed subsequent to admission showed no narrowing or distension of the bile ducts. As the jaundice symptoms were not improved by the oral administration of ursodeoxycholic acid (300 mg/day) that had been started immediately after admission, endoscopic retrograde cholangiopancreatography (ERCP) was performed on hospital day 14. This also showed no abnormalities of the bile ducts. After considerating its potential effects for improving jaundice, endoscopic nasobiliary drainage (ENBD) was performed on the same day and was followed by immediate improvements in pruritus and jaundice. Detailed examinations were performed to identify the cause of the jaundice, which was suspected to be viral hepatitis, autoimmune hepatitis or drug-induced liver injury, however, there were no findings suggestive of any of these conditions. Following a further increase in bilirubin levels, confirmed by additional blood tests, a liver biopsy was performed. Histological findings were consistent with the histological features of benign recurrent intrahepatic cholestasis (BRIC). Although ursodeoxycholic acid is used as a first-line treatment in most cases of BRIC, ENBD should also be considered for patients not responding to this treatment.
Water absorption and blistering of glass fibre-reinforced polymer marine laminates with nanoparticle-modified coatings

Macro and microstructural damage was studied in typical glass fibre-reinforced polymer laminates with two types of coating systems – (a) isophtalic gel coat: pure or mixed with SiO2 nanoparticles 5 wt% (5%N) or 10 wt% (10%N) and (b) a two-layer coating system: urethane-modified vinyl ester-based gel coat and additional polyester barrier coat layer. Accelerated tests were performed at 50℃ for 50 days for specimens with nanoparticle-modified gel and for the specimens with or without a barrier coat. Long-term ageing behaviour at 23℃ was assessed for the two-layer systems. Nanoparticle-reinforced specimens (10%) showed some advantage over ‘barrier coat systems' in terms of blister incubation time (16 and 13 days, respectively), while for 5% and 0% nanoparticles, blister incubation times were 3 and 7 days, respectively. Round and/or acicular blisters were observed on the examined surfaces. The varying size, shape and distribution of blisters was illustrated by macro and micrographs showing various failure modes associated with surface blisters.
Generalised Coupled Tensor Factorisation

We derive algorithms for generalised tensor factorisation (GTF) by building upon the well-established theory of Generalised Linear Models. Our algorithms are general in the sense that we can compute arbitrary factorisations in a message passing framework, derived for a broad class of exponential family distributions including special cases such as Tweedie's distributions corresponding to β-divergences. By bounding the step size of the Fisher Scoring iteration of the GLM, we obtain general updates for real data and multiplicative updates for non-negative data. The GTF framework is, then extended easily to address the problems when multiple observed tensors are factorised simultaneously. We illustrate our coupled factorisation approach on synthetic data as well as on a musical audio restoration problem.
Study on the Shape of Occurrence and Developing of Evaporation Wave in Short Pipe

When liquid within short pipe is placed suddenly into low-pressure environment from an atmospheric pressure, the effects of temperature and pressure on occurrence and developing of evaporation wave are studied, the variations of flow patterns are observed. The experimental results show that flow patterns of liquid within short pipe gradually change from bubble rising to blazing bubble flow until annular flow with a decrease in initial environmental pressure. Intensity and moving speed of the evaporation wave increased with a decrease of the diameter of pipe and pressure, and an increase of the fluid temperature. The evaporation wave fronts are in a state of explosive vaporization, instantaneous propagation velocity of evaporation wave fronts is violently fluctuating.
Feature detection and matching in images with radial distortion

Image keypoints are broadly used in robotics for different purposes, ranging from recognition to 3D re-construction, passing by SLAM and visual servoing. Robust keypoint matching across different views is problematic because of the relative motion between camera and scene that causes significant changes in feature appearance. The problem can be partially overcome by using state-of-the-art methods for keypoint detection and matching, that are resilient to common affine transformations such as changes in scale and rotation. Unfortunately, these approaches are not invariant to the radial distortion present in images acquired by cameras with wide field-of-view. This article proposes modifications to the Scale Invariant Feature Transform (SIFT), that improve the repeatability of detection and effectiveness of matching in the presence of distortion, while preserving the characteristics of invariance to scale and rotation. These modifications require an approximate modeling of the image distortion, and consist in using adaptative gaussian filtering for detection and implicit gradient correction for description. Extensive experiments, with both synthetic and real images, show that our method outperforms explicit distortion correction using image rectification.
The End of Internet Architecture

Architecture. There’s a lot of it about. Do we need it? Recent years have seen considerable publishing activity in the area of “internet architecture”. This paper steps back and asks a more radical question: is an internet architecture a good thing at all? Are we at a point in the development of distributed communications systems where the concept should be replaced by a different way of dividing up the design space? This is not a paper about what the Right internetwork architecture should look like, but rather whether the very idea of a network architecture at this point in history is a help or hindrance in moving communication technology (and research in particular) forward. We first examine critically what the role of the internet architecture is today. We argue that instead of acting as useful guide for network practitioners of all kinds (as it has in the past), the principle function the architecture performs these days is to keep the fields of “networking” and “distributed systems” separate, to the detriment of both. Put simply, the internet architecture, and more broadly the concept of a network architecture, is now in the way. At the same time, trends in networking and computational hardware, and in particular in the kinds of testbeds available to researchers to validate their ideas, have made it both feasible and compelling to do research that finesses network architecture as an issue completely, and concentrates on the broader problem of building, deploying, and operating large-scale distributed applications. Fortunately, this does not render research into “internet architecture” irrelevant, but it does call for a respinning of many of the ideas in a different context. This paper concludes by examining the new research opportunities in the area, and how they relate to tradition challenges in “architecture”.
A Rare Case; Bilateral Macular Pseudohole and High Hypermetropia in 7-Years Old Child

Background: To report a 7-years old child with bilateral macular pseudohole and high hypermetropia. Methods: Full ophthalmic examination including The Watzke-Allen test, retinal photographs and optical coherence tomography was performed. Results: There were bilateral high hypermetropia and ambliopia. There were no history of ocular diseases, trauma or surgery. Uncorrected visual acuity was counting finger at 3 meters in each eye. Manifest refraction was +13.0+1.0@90 OD, +13.5+1.0@90 OS. Best corrected visual acuity was 20/70 in the right eye and 20/70 in the left eye. Cover tests were normal. There were macular hole views in both eyes. Optical coherence tomography findings were compatible with epiretinal membrane and macular pseudohole. Conclusion: The coexistence of bilateral idiopathic epiretinal membrane and bilateral high hypermetropia in a child is noteworthy and first in the literatures.
Dynamic Pricing in the Presence of Social Learning and Strategic Consumers

When a product of uncertain quality is first introduced, consumers may choose to strategically delay their purchasing decisions in anticipation of the product reviews of their peers. This paper investigates how the presence of social learning affects the strategic interaction between a dynamic-pricing monopolist and a forward-looking consumer population, within a simple two-period model. Our analysis yields three main insights. First, we find that the presence of social learning has significant structural implications for optimal pricing policies: In the absence of social learning, decreasing price plans are always preferred by the firm; by contrast, in the presence of social learning we find that (i) if the firm commits to a price path ex ante (preannounced pricing), an increasing price plan is typically announced, whereas (ii) if the firm adjusts price dynamically (responsive pricing), prices are initially low and may either rise or decline over time. Second, we establish that under both preannounced an.
Cephalotheca sulfurea (Ascomycota, Sordariomycetes), a new fungal pathogen of the farmed rainbow trout Oncorhynchus mykiss.

The first case of visceral mycotic infection due to Cephalotheca sulfurea (Cephalothecaceae, Ascomycota) is documented in farmed rainbow trout from a raceway culture system. The disease clinically manifested as a hyperaemic area in the liver of the fish, and histological examination using silver and PAS staining showed the presence of numerous foci of hyphae and spores. The causative agent was first isolated in pure culture from the liver and identified using morphological characteristics. Sequence data from ITS and LSU rDNA also clearly confirmed C. sulfurea as the causal agent. The pathogenicity of related species belonging to the family Cephalothecaceae has been well-documented in humans and dogs (superficial as well as systemic infections). However, C. sulfurea has never been reported as a pathogen of humans or animals, including marine and freshwater fishes. The morphological identification of C. sulfurea is difficult due to its similarity to several different fungal genera, and molecular methods are strongly recommended for reliable identification.
Support in Abstract Argumentation

In this paper, we consider two drawbacks of Cayrol and Lagasque-Schiex's meta-argumentation theory to model bipolar argumentation frameworks. We consider first the “lost of admissibility” in Dung's sense and second, the definition of notions of attack in the context of a support relation. We show how to prevent these drawbacks by introducing support meta-arguments. Like the model of Cayrol and Lagasque-Schiex, our formalization confirms the use of meta-argumentation to reuse Dung's properties. We do not take a stance towards the usefulness of a support relation among arguments, though we show that if one would like to introduce them, it can be done without extending Dung's theory. Finally, we show how to use meta-argumentation to instantiate an argumentation framework to represent defeasible support. In this model of support, the support relation itself can be attacked.
A relationship between spline-based deformable models and weighted graphs in non-rigid matching

Deformable models are central to non-rigid motion analysis, shape matching and non-rigid medical image registration. Spline-based deformations are a very popular class of parameterizations of deformable models and have been heavily used in multiple domains. In a somewhat separate sub-field, weighted graphs are a frequently used object parameterization. Graph matching using weighted graph object parameterizations finds application in a spectrum ranging from rigid pose estimation to deformable object recognition. Here, we demonstrate a hitherto unsuspected relationship between spline-based deformable models and weighted graphs. It turns out that spline parameterizations in the kernel representation can be used to construct equivalent weighted graphs. With this connection established, we envision a cross-fertilization between these two seemingly disparate sub-fields of computer vision.
Low-Power ASK Detector for Low Modulation Indexes and Rail-to-Rail Input Range

A high-performance ultrahigh-frequency amplitude shift keying (ASK) detector for low-power radio-frequency (RF) receivers is proposed. The circuit is based on a high-gain common-source topology with a feedback loop that provides adaptive biasing. Hence, high sensitivity and rail-to-rail input operation are achieved along with low power consumption. The detector was implemented in a standard 130-nm complementary metal-oxide-semiconductor technology. Sensitivity measurements demonstrate correct detection of a 2-Mb/s ASK-modulated 915-MHz signal with a peak level and a modulation index of around 200 mV and 5%, respectively, which means an envelope signal amplitude of as low as 5 mV. The circuit draws less than 3.4 μA from a 1.2-V power supply while operating with rail-to-rail RF variations and modulation indexes from 5% to 100%. This performance makes the detector suitable for batteryless systems with RF energy harvesting.
Draft Genome Sequence of the Naturally Competent Bacillus simplex Strain WY10

ABSTRACT We sequenced a naturally competent bacterial isolate, WY10, cultured from a Wyoming soil sample. Sequence analysis revealed that WY10 is a novel strain of Bacillus simplex. To our knowledge, WY10 is the first B. simplex strain to be characterized as naturally competent for DNA uptake by transformation.
Estimating the target of interaction for each human in office space with obstacles using 3D observation

Conventional studies on human behavior recognition have mainly focused on individual actions, including facial expressions and postures. However, most human behavior involves face-to-face interactions with other humans or objects, such as PCs. The previous work on recognizing face-to-face interaction focused on recognition of each group of humans engaged in conversation in an open space, which is considered a free space without obstacles. However, face-to-face conversation in our daily activities also occurs in a space such as an office with various obstacles, which could interfere with the interaction. To cope with this interference, the arrangement of obstacles and humans in the space should be considered. Moreover, in an office space, humans interact not only with other humans but also with certain interactive objects, such as PCs. This study aims to detect the target of interaction of each person in a space with obstacles by considering the 3D positions and orientations of humans, interactive objects, and other obstacles. The 3D arrangement of humans and obstacles is obtained by observing the space with an RGB-D camera.
Design of negative index metamaterials in optical communication range

Negative index metamaterial (NIM) has been designed to have polarization insensitive operation for normal incident waves in the optical communication wavelength region. The designed metamaterial has an effective refractive index of Re(n)=-1 and a ratio of-Re{n}/Im{n} = 5.2 at about 1500 nm.
Binocular stereovision camera calibration

In view of the binocular stereo vision calibration problem, this paper offers a method of camera calibration which is between the traditional calibration and the self-calibration. To compare with traditional methods, set the internal parameters distortion parameters and external parameters calibrated respectively. First of all, working out the internal parameters by Zhang Z.Y plane calibration method; secondly, calculating the distortion parameters based on the radial distortion lens; finally, discussing the calibration methods of external parameters in the case of the camera is moving, to avoid the problem of recalibration when the camera is moving in original calibration environment. The experiment according to the template principle of traditional calibration, combined with binocular stereovision model, verifies the feasibility of this separation calibration method.
Characterization of LDL Particle Size Among Carriers of a Defective or a Null Mutation in the Lipoprotein Lipase Gene: The Québec LIPD Study

Objective—The objective of the present study was to compare the impact of the null P207L and defective D9N mutations in the LPL gene on LDL particle size among heterozygous carriers. Methods and Results—LDL particle size was measured on whole plasma by 2% to 16% non-denaturing polyacrylamide gradient gel electrophoresis in a cohort of 206 heterozygous carriers of either the P207L or the D9N mutation. The P207L carriers (N=88) presented with a more atherogenic lipoprotein-lipid profile compared with the D9N carriers (N=118). Accordingly, LDL particle size was smaller in the P207L carriers than in the D9N subjects (248.8± 1.0 vs 254.5±1.0 Å, P < 0.001), and the difference remained significant after adjustment for plasma triglyceride (TG) levels. The difference in LDL diameter between the P207L and the D9N carriers was 3-fold greater in individuals with plasma TG levels >3.5 mmol/L than in subjects with TG ≤3.5 mmol/L. The factors that statistically contributed to LDL particle size variation in multivariate analyses were plasma TG levels (11.6%) and age (6.4%) in subjects with TG levels ≤3.5 mmol/L and HDL cholesterol levels (15.5%) and the LPL gene mutation (null versus defective, 7.0%) in patients with TG levels >3.5 mmol/L. Conclusions—These results suggest that the null P207L mutation in the LPL gene has a greater impact on LDL particle size than the defective D9N mutation and that this mutation-specific effect is amplified at greater plasma TG concentrations.
Lipid composition and food quality of some freshwater phytoplankton for cladoceran zooplankters

The nutritional value of several planktonic algae was tested by means of feeding trials with three cladoceran zooplankters. The algae were monocultures and included two blue-greens, four greens and four flagellates with a size range of 5-48 u,m. The specific growth rates of the zooplankters were chosen as the measure of the nutritional value of the algae. The three cladocerans showed large differences in growth rate in the different algae, but the two cryptomonads were without doubt best suited as food for all. The fatty acid composition for the cryptomonads were different from the other algae. They contained high percentages of the polyunsaturated fatty acids 20:5u)3 (EPA) and 22:6w3 (DHA), which also are common in fish. It is suggested that the lipid composition is a probable factor determining the nutritional quality of the algae.