Miracle-dz/UniFAR-FTUs huggingface dataset:
Effects of Photobiomodulation in Sports Performance: A Literature Review

The main goal of this study is to analyze photobiomodulation therapy’s effectiveness on improving sports practice. Secondarily, the included studies were methodologically analyzed to verify their quality. A review and appraisal of literature found in Web of Science, ProQuest and Scopus databases was carried out. To evaluate the risk of bias of the included studies. The Physiotherapy Evidence Database (PEDro) scale and PEDro Internal Validity Scale (IVS) checklists were used. The included randomized clinical trials were in English, conducted on humans and published since 2016. A total of 15 randomized clinical trials were included, 4 of which found an improvement in oxygen volume after an aerobic stress test, while 2 showed no change. Muscle damage decreased in five studies, however, in two of them muscle damage did not change. Blood lactate concentration decreased in two of the studies, while in three of them there was no difference. Muscle soreness was lower in three studies, however, in four of the articles no change was demonstrated. All selected studies were of good methodological quality. On the IVS, six RCTs had a high internal quality and nine of them moderate. Photobiomodulation therapy has a positive effect on sports performance. Scientific studies on the subject are limited and more research in this line is needed.
Multi-Omics Profiling of Hypertrophic Cardiomyopathy Reveals Altered Mechanisms in Mitochondrial Dynamics and Excitation–Contraction Coupling

Hypertrophic cardiomyopathy is one of the most common inherited cardiomyopathies and a leading cause of sudden cardiac death in young adults. Despite profound insights into the genetics, there is imperfect correlation between mutation and clinical prognosis, suggesting complex molecular cascades driving pathogenesis. To investigate this, we performed an integrated quantitative multi-omics (proteomic, phosphoproteomic, and metabolomic) analysis to illuminate the early and direct consequences of mutations in myosin heavy chain in engineered human induced pluripotent stem-cell-derived cardiomyocytes relative to late-stage disease using patient myectomies. We captured hundreds of differential features, which map to distinct molecular mechanisms modulating mitochondrial homeostasis at the earliest stages of pathobiology, as well as stage-specific metabolic and excitation-coupling maladaptation. Collectively, this study fills in gaps from previous studies by expanding knowledge of the initial responses to mutations that protect cells against the early stress prior to contractile dysfunction and overt disease.
Development of Open Ended Based Mathematics E-Modules to Enhance Students' Critical Thinking Ability

In the current era of globalization, students' critical thinking skills are still low, so teaching materials that support learning are needed. In the learning process, educators have not developed teaching materials that are following technological advances, and existing teaching materials use more routine questions so that students only accept and follow the flow and rules rather than experimenting and finding answers or solutions on their own. Therefore, this study aims to produce an open-ended based mathematics e-module product on a system of two-variable linear equations for class VIII students of junior high school, to determine the feasibility of the product in terms of valid, practical, and effectiveness, to determine the increase in students' critical thinking skills after using e-module. This is development research with the ADDIE model (Analysis, Design, Development, Implementation, and Evaluation). This research was conducted at a Public Middle School in Purworejo for the 2021/2022 academic year. The data collection technique in this study was carried out through questionnaires and tests. The instruments used in this study were validation sheets, questionnaires, and tests. Data analysis techniques use validity, practicality, and effectiveness tests. The results of this study are open-ended-based mathematics e-modules to improve students' critical thinking skills. The product test results showed that the e-module validity score obtained a percentage of 80% from material experts and 82.5% from media experts. The results of the practicality test of the e-module obtained a percentage of 78% from the limited test and a percentage of 74% from the wide test. The results of the effectiveness of open-ended-based mathematics e-module products, namely the N-Gain test, obtained 0.6 in the medium category. The data shows that the e-module developed in this study is categorized as feasible. Students' critical thinking skills after using open-ended-based mathematics e-modules have increased.
Applicability Analysis of a Multi-Filar Meander R-SFCL and an RSC-DCCB in an MMC-MTDC Grid

Modular multilevel converters (MMC)-based high voltage direct current (HVDC) topology is an effective solution to solve the power transmission demand between countries. However, the initial fault current can rise to several tens of kA within a few ms by capacitor discharge during a fault. This fault current can permanently damage the converter components and cables. Therefore, to increase the stability of the system, the protection of the DC system is very important. DC system protection methods include circuit breaker technologies and current limiting technologies. We have selected a circuit breaker with combined resonant current source (RCS) and a resistive superconducting fault current limiter (SFCL) as protection methods for the DC system. The RSC-DC circuit breaker has no conduction power losses by on-state voltage drop. Therefore, it can provide stable interruption compared to a solid-state DC circuit breaker. Since the resistive SFCL has a very fast response time, it can effectively limit the rapidly rising initial fault current. We wound the superconducting tape by the multi-filar meander method. This method can increase the length of the superconducting tape used and speed up the bubble diffusion during quenching. We modeled an MMC-HVDC grid, resistive SFCL, and RCS DC circuit breaker using PSCAD/EMTDC. In this paper, the interrupting and current limiting characteristics are discussed when the resistive SFCL and the RCS-DC circuit breaker proposed by us are connected to the MMC-based MTDC grid. In the simulation, the current limiting factor of resistive SFCL was up to about 58%. In addition, the combination of resistive SFCL and RCS-DC circuit breaker can shorten the interruption time when the fault occurs.
Anterior Cruciate Ligament Injury Prevention and Rehabilitation

At all levels of American football, knee injuries are common, with injuries to the anterior cruciate ligament (ACL) making up a significant proportion. Historically, ACL injuries were career-altering for professional players, but innovative techniques in surgery and rehabilitation have returned many to the field. While there is a consensus on surgical techniques for ACL reconstruction, significant discrepancies remain on injury prevention and rehabilitation programs. This review article describes the burden of ACL injury on players in the National Football League, best practices in injury prevention and rehabilitation, and evidence-based recommendations for preparing injured athletes to return to play.
Effect of genotype and environment on agronomical characters of alfalfa (Medicago sativa L.) in a typical acidic soil environment in southwest China

Alfalfa (Medicago sativa L.), an important perennial legume forage crop with high nutritional value and forage yield, is widely used in animal husbandry. However, it is very sensitive to aluminum, which severely limits its growth in acidic soils. In this study, we analyzed the genotype variation of each agronomic trait in 44 alfalfa varieties in two acidic soil environments. Then, analysis of variance (ANOVA) of the variance components was performed using the Residual Maximum Likelihood (REML). The best linear unbiased predictor analysis was used to obtain the mean trait of each variety, and the mean values were used to construct the mean matrix of varieties × traits and interaction analysis of varieties × years. The results showed that there was significant (P < 0.05) genotypic variation for each trait of the 44 varieties and the genetic diversity was abundant. The average repeatability (R value) of interannual plant height (PH), stem thickness (ST), number of branches (NS), fresh weight (FW), total fresh weight (TFW), and total dry weight (TDW) was high (0.21–0.34), whereas the genetics were relatively stable. PH, NS, FW, TFW, and dry weight (DW) were positively correlated (P < 0.01) with TDW. Six alfalfa varieties (Algonquin, Xinjiang daye, Trifecta, Vernal, WL354HQ, and Boja) with excellent TDW and TFW were identified in different years, environmental regions, and climatic altitudes. Our research results can provide suggestions and critical information regarding the future improvement and development of new alfalfa strains and varieties that are resistant to acidic soil conditions.
Estimation of Glomerular Filtration Rate in Obese Patients: Utility of a New Equation

There is no consensus on the best equation to estimate glomerular filtration rate (eGFR) in obese patients (OP). Objective: to evaluate the performance of the current equations and the new Argentinian Equation (“AE”) to estimate GFR in OP. Two validation samples were used: internal (IVS, using 10-fold cross-validation) and temporary (TVS). OP whose GFR was measured (mGFR) with clearance of iothalamate between 2007/2017 (IVS, n = 189) and 2018/2019 (TVS, n = 26) were included. To evaluate the performance of the equations we used: bias (difference between eGFR and mGFR), P30 (percentage of estimates within ±30% of mGFR), Pearson’s correlation (r) and percentage of correct classification (%CC) according to the stages of CKD. The median age was 50 years. Sixty percent had grade I obesity (G1-Ob), 25.1% G2-Ob and 14.9% G3-Ob, with a wide range in mGFR (5.6–173.1 mL/min/1.73 m2). In the IVS, AE obtained a higher P30 (85.2%), r (0.86) and %CC (74.4%), with lower bias (−0.4 mL/min/1.73 m2). In the TVS, AE obtained a higher P30 (88.5%), r (0.89) and %CC (84.6%). The performance of all equations was reduced in G3-Ob, but AE was the only one that obtained a P30 > 80% in all degrees. AE obtained better overall performance to estimate GFR in OP and could be useful in this population. Conclusions from this study may not be generalizable to all populations of obese patients since they were derived from a study in a single center with a very specific ethnic mixed population.
Vertex-Magic Total Labeling Algorithms on Unicycle Graphs and Some Graphs Related to Wheels

Normal 0 false false false Abstract Let G be a graph with vertex set V and edge set E , where | V | and | E| be the number of vertices and edges of G. A bijection λ : V E E ® {1, 2, …, |V| + |E|} is called a vertex - magic total labeling if there is a constant k so that the weight of vertex x, w λ ( x ) = λ(x) + a y I N(x) λ(xy) = k , for all x in V where N(x) is the set of vertices adjacent to x . This paper gives algorithms to generate all vertex - magic total labelings on some classes of unicycle graphs (suns and tadpoles) and some classes of graph related to wheels (friendships, fans, generalized J ahangirs) . Using those algorithms , we enumerate all non isomorphic vertex-magic total labelings on those classes of graph s for some values of |V| . Keywords: Fan, Friendship, Generalized J ahangir, Sun, Tadpole, Unicycle, Vertex magic total labeling, Wheel. Algoritma Pelabelan Total Simpul Ajaib pada Graf Unicyle dan Beberapa Graf yang Terkait dengan Roda Abstrak Misalkan G adalah graf dengan himpunan simpul V dan himpunan busur E dengan | V | dan | E| menyatakan banyak simpul dan banyak busur pada G. Fungsi bijektif λ : V E E ® {1, 2, …, |V| + |E|} disebut pelabelan total simpul ajaib jika ada konstanta k sedemikian sehingga bobot simpul x, w λ ( x ) = λ(x) + a y I N(x) λ(xy) = k , untuk setiap x di V dengan N(x) menyatakan, himpunan simpul yang berdekatan dengan x . Makalah ini memberikan algoritma-algoritma untuk menghasikan semua pelabelan-pelabelan total simpul ajaib pada beberapa kelas graf unicycle (matahari dan kecebong) dan beberapa kelas graf yang terkait dengan roda (friendship, kipas, generalized J ahangir) . Menggunakan algoritma-algoritma tersebut, dienumerasi semua pelabelan total simpul ajaib yang tidak isomorfik pada kelas-kelas graf yang menjadi perhatian, untuk beberapa nilai dari |V| . Kata kunci: F riendship, Generalized Jahangir, Kecebong, Kipas, Matahari, Pelabelan total simpul ajaib, Unicycle. /* Style Definitions */ table.MsoNormalTable {mso-style-name:"Table Normal"; mso-tstyle-rowband-size:0; mso-tstyle-colband-size:0; mso-style-noshow:yes; mso-style-parent:""; mso-padding-alt:0cm 5.4pt 0cm 5.4pt; mso-para-margin:0cm; mso-para-margin-bottom:. 0001pt; mso-pagination:widow-orphan; font-size:10.0pt; font-family:"Times New Roman"; mso-ansi-language:#0400; mso-fareast-language:#0400; mso-bidi-language:#0400;}
A simple technique for measuring thickness distribution of transparent plates from a single image by using the sampling moiré method

A simple measurement technique for the thickness distribution of transparent plates is proposed by using the sampling moiré method. The thickness distribution is automatically analyzed by measuring the phase difference of the moiré fringe obtained from a single image, consistent with light refraction. The relationship between the actual thickness and phase difference of the moiré fringe is calibrated by using glass plates of known thicknesses. The thickness measured by the present method was found to be in agreement with measurements using a digital micrometer. In our experiment, the average error in glass plate thickness was 1.9% over a 3.5 mm measurement range. Experimental results indicate that the present method can be useful for nondestructive measurements of the thickness distribution of various transparent plates.
Cholesterol-Related lncRNAs as Response Predictors of Atorvastatin Treatment in Chilean Hypercholesterolemic Patients: A Pilot Study

Statins are currently the treatment of choice for hypercholesterolemia. However, wide interindividual variability has been observed in the response to treatment. Recent studies have reported the role of lncRNAs in the metabolism of lipids; nevertheless, there are few studies to date that show their role in the response to treatment with statins. Thus, the aim of this study was to assess the levels of expression of three lncRNAs (RP1-13D10.2; MANTIS; lncHR1) associated with genes involved in cholesterol homeostasis in leukocyte cells of hypercholesterolemic patients after treatment with atorvastatin and compare them with levels in subjects with normal cholesterol levels. A secondary aim was to assess the levels of expression in monocytic THP-1 cells differentiated to macrophages. The study included 20 subjects with normal cholesterol (NC) levels and 20 individuals with hypercholesterolemia (HC). The HC patients were treated with atorvastatin (20 mg/day/4 weeks). THP-1 cells were differentiated to macrophages with PMA and treated with different doses of atorvastatin for 24 h. Expression of lncRNAs was determined by RT-qPCR. The lncRNAs RP1-13D10.2 (p < 0.0001), MANTIS (p = 0.0013) and lncHR1 (p < 0.0001) presented increased expression in HC subjects compared with NC subjects. Furthermore, atorvastatin had a negative regulatory effect on the expression of lncHR1 (p < 0.0001) in HC subjects after treatment. In vitro, all the lncRNAs showed significant differences in expression after atorvastatin treatment. Our findings show that the lncRNAs tested present differential expression in HC patients and play a role in the variability reported in the response to atorvastatin treatment. Further research is needed to clarify the biological impact of these lncRNAs on cholesterol homeostasis and treatment with statins.
Treatment of a Chronic Open Wound Related to Sacrococcygeal Pilonidal Cyst and Squamous Cell Carcinoma: A Case Report

Pilonidal sinus disease is a cystic lesion or draining sinus tract involving the sacrococcygeal area. A long-standing sinus tract can lead to squamous cell carcinoma in the tract and overlying skin. We present the case of a 56-year-old female patient who had undergone pilonidal cyst excision whose postoperative pathologic report indicated squamous cell carcinoma. The sinus tract did not heal for 3 months, and the patient was then transferred to our clinic. Our team conducted a thorough resection of the cystic lesion and the overlying skin, followed by the relocation of two flaps to restore the skin and soft tissue defect. The patient recovered after a 1-month wound healing period. Postoperative fluid collection or discharge did not occur, and the patient achieved the ability to perform daily activities such as walking and eating meals in the sitting position. Adequate resection of cystic lesions is necessary when treating pilonidal sinus disease. A benign cyst can turn into a malignant lesion, and additional wide excision followed by tissue restoration is a therapeutic option for curative treatment.
Tkachenko waves in rotating superfluid helium

The resonant response of a stack of disks driven into torsional oscillation within a container of rotating superfluid helium has been observed. It is shown that the oscillation modes excited are related to Tkachenko waves, that is, vortex displacement waves in the vortex array propagating in a direction transverse to the vortex lines. In particular, the resonances occur at peaks in the vortex wave density of states.
Time-frequency filter banks with perfect reconstruction

The authors present two methods for the design of perfect-reconstruction filter banks corresponding to a partition of the time-frequency plane into nonoverlapping pass regions. The first method is an extension of the concept of optimal time-frequency projection filters. The second method is an approximate filter bank design with reduced computational cost. <<ETX>>
A Multi-Layered 3D NDT Scan-Matching Method for Robust Localization in Logistics Warehouse Environments

This paper proposed a multi-layered 3D NDT (normal distribution transform) scan-matching approach for robust localization even in the highly dynamic environment of warehouse logistics. Our approach partitioned a given 3D point-cloud map and the scan measurements into several layers regarding the degree of environmental changes in the height direction and computed the covariance estimates for each layer using 3D NDT scan-matching. Because the covariance determinant is the estimate’s uncertainty, we can determine which layers are better to use in the localization in the warehouse. If the layer gets close to the warehouse’s floor, the degree of environmental changes, such as the cluttered warehouse layout and position of boxes, would be significantly large, while it has many good features for scan-matching. If the observation at a specific layer is not explained well enough, then the layer for localization can be switched to other layers with lower uncertainties. Thus, the main novelty of this approach is that localization robustness can be improved even in very cluttered and dynamic environments. This study also provides the simulation-based validation using Nvidia’s Omniverse Isaac sim and detailed mathematical descriptions for the proposed method. Moreover, the evaluated results of this study can be a good starting point for further mitigating the effects of occlusion in warehouse navigation of mobile robots.
Developing a non-invasive diagnostic model for pediatric Crohn’s disease using RNA-seq analysis

Introduction: Pediatric Crohn’s disease is a chronic inflammatory condition that affects the digestive system in children and adolescents. It is characterized by symptoms such as abdominal pain, diarrhea, weight loss, and malnutrition, and can also cause complications like growth delays and delayed puberty. However, diagnosing pediatric Crohn’s disease can be difficult, especially when it comes to non-invasive methods. Methods: In this study, we developed a diagnostic model using RNA-seq to analyze gene expression in ileal biopsy samples from children with Crohn’s disease and non-pediatric Crohn’s controls. Results: Our results showed that pediatric Crohn’s disease is associated with altered expression of genes involved in immune response, inflammation, and tissue repair. We validated our findings using two independent datasets from the Gene Expression Omnibus (GEO) database, as well as through one prospective independent dataset, and found that our model had a high accuracy rate. Discussion: These findings suggest the possibility of non-invasive diagnosis for pediatric Crohn’s disease and may inform the development of targeted therapies for this condition.
A correction for powder diffraction peak asymmetry due to axial divergence

Analysis of a crystal structure using the Rietveld profile technique requires a suitable description of the shape of the peaks. In general, modern refinement codes include accurate formulations for most effects; however, the functions used for peak asymmetry are semi-empirical and take very little account of diffraction optics. The deficiencies in these methods are most obvious for high-resolution instruments. This study describes the implementation of powder diffraction peak profile formulations devised by van Laar & Yelon [J. Appl. Cryst. (1984), 17, 47-54]. This formalism, which describes the asymmetry due to axial divergence in terms of finite sample and detector sizes, does not require any free parameters and contains intrinsic corrections for the angular dependence of the peak shape. The method results in an accurate description of the observed profiles for a variety of geometries, including conventional X-ray diffractometers, synchrotron instruments with or without crystal analyzers and neutron diffractometers. other more recent applications, such as auto-indexing and accurate lattice-parameter determination in diamondanvil cells and other constrained environments, it is essential that the effects of axial divergence are properly described in the peak-shape function. In a diffraction experiment with a nondivergent point source and a randomly oriented powdered sample, the radiation scattered by a given diffraction line will lie on the surface of a cone with semi-angle 20. The entrance slit of a detector lies on the surface of a right cylinder with axis parallel to the 20 axis of the diffractometer. The intersection of the diffraction cone with the detector cylinder is an ellipse. As 120-901 increases, the ellipticity decreases, as can be seen in a Debye-Scherrer film. The center of the ellipse is at zero for 20 90 ° . As shown in Fig. 1, this curvature leads to a peak asymmetry because intensity from the ends of the intercepted piece of the diffraction cone will intersect the detector slit on the side of the peak closer to the center of the