Miracle-dz/UniFAR-FTUs huggingface dataset:
Constraints on Extended Quintessence from High-redshift Supernovae

We obtain constraints on quintessence models from magnitude-redshift measurements of 176 type Ia Super-novae. The considered quintessence models are ordinary quintessence, with Ratra-Peebles and SUGRA potentials , and extended quintessence with a Ratra-Peebles potential. We compute confidence regions in the Ω m0 − α plane and find that for SUGRA potentials it is not possible to obtain useful constraints on these parameters; for the Ratra-Peebles case, both for the extended and ordinary quintessence we find α ∼ < 0.8, at the 1σ level. We also consider simulated dataset for the SNAP satellite for the same models: again, for a SUGRA potential it will not be possible to obtain constraints on α, while with a Ratra-Peebles potential its value will be determined with an error ∼ < 0.6. We evaluate the inaccuracy made by approximating the time evolution of the equation of state with a linear or constant w(z), instead of using its exact redshift evolution. Finally we discuss the effects of different systematic errors in the determination of quintessence parameters.
The Impact of Magnetic Field on the Thermal Evolution of Neutron Stars

The impact of strong magnetic fields B > 1013 G on the thermal evolution of neutron stars is investigated, including crustal heating by magnetic field decay. For this purpose, we perform 2D cooling simulations with anisotropic thermal conductivity considering all relevant neutrino emission processes for realistic neutron stars. The standard cooling models of neutron stars are called into question by showing that the magnetic field has relevant (and in many cases dominant) effects on the thermal evolution. The presence of the magnetic field significantly affects the thermal surface distribution and the cooling history of these objects during both the early neutrino cooling era and the late photon cooling era. The minimal cooling scenario is thus more complex than generally assumed. A consistent magnetothermal evolution of magnetized neutron stars is needed to explain the observations.
The Rodney L . White Center for Financial Research The Role of Trading Halts in Monitoring a Specialist Market

We model an exchange as a collection of specialists, each a monopolist market maker in a subset of the stocks listed on the exchange. Specialists can obtain net private benefits at the expense of the exchange (the collection of all specialists) by quoting a privately optimal pricing schedule. Conversely, a coordinated pricing schedule makes all specialists and customers better off. However, coordination requires a system of monitoring and punishment, which can break down when information asymmetries between the exchange and a specialist are high. This breakdown can cause the specialist to seek a temporary halt to trading to alleviate unjustified punishment, or the exchange to halt trading to prevent the quoting of damaging privately optimal pricing schedules. We use a sample of NYSE halts and a proxy for the exchange-specialist information asymmetry to test this theory. As predicted, we find a significant increase in estimated information asymmetry immediately preceding trading halts.
Role of Cholinergic Innervation and RGS2 in Atrial Arrhythmia

The heart receives sympathetic and parasympathetic efferent innervation as well as the ability to process information internally via an intrinsic cardiac autonomic nervous system (ICANS). For over a century, the role of the parasympathetics via vagal acetylcholine release was related to controlling primarily heart rate. Although in the late 1800s shown to play a role in atrial arrhythmia, the myocardium took precedence from the mid-1950s until in the last decade a resurgence of interest in the autonomics along with signaling cascades, regulators, and ion channels. Originally ignored as being benign and thus untreated, recent emphasis has focused on atrial arrhythmia as atrial fibrillation (AF) is the most common arrhythmia seen by the general practitioner. It is now recognized to have significant mortality and morbidity due to resultant stroke and heart failure. With the aging population, there will be an unprecedented increased burden on health care resources. Although it has been known for more than half a century that cholinergic stimulation can initiate AF, the classical concept focused on the M2 receptor and its signaling cascade including RGS4, as these had been shown to have predominant effects on nodal function (heart rate and conduction block) as well as contractility. However, recent evidence suggests that the M3 receptor may also playa role in initiation and perpetuation of AF and thus RGS2, a putative regulator of the M3 receptor, may be a target for therapeutic intervention. Mice lacking RGS2 (RGS2−/−), were found to have significantly altered electrophysiological atrial responses and were more susceptible to electrically induced AF. Vagally induced or programmed stimulation-induced AF could be blocked by the selective M3R antagonist, darifenacin. These results suggest a potential surgical target (ICANS) and pharmacological targets (M3R, RGS2) for the management of AF.
Common-mode resonances in ultra wide band connected arrays of dipoles: Measurements from the demonstrator and exit strategy

A 6–9 GHz prototype array of dual-polarized connected dipoles has been manufactured. The array is composed by two orthogonal sets of 8×8 elements for each polarization (128), arranged in an egg-crate configuration. Preliminary measurements highlighted the presence of unpredicted common-mode resonances excited in the vertical feeding lines. An analysis of the common-mode excitation is carried out and exit strategies for a design of a resonance-free connected array are presented.
Risk Aversion, Overconfidence and Private Information as Determinants of Majority Thresholds

We present and experimentally test a theoretical model of majority threshold determination as a function of voters’ risk preferences. The experimental results confirm the theoretical prediction of a positive correlation between the voter's risk aversion and the corresponding preferred majority threshold. Furthermore, the experimental results show that a voter's preferred majority threshold negatively relates to the voter's confidence about how others will vote. Moreover, in a treatment in which individuals receive a private signal about others’ voting behaviour, the confidence-related motivation of behaviour loses ground to the signal's strength.
Resistance to the Antimicrobial Agent Fosmidomycin and an FR900098 Prodrug through Mutations in the Deoxyxylulose Phosphate Reductoisomerase Gene (dxr)

ABSTRACT There is a pressing need for new antimicrobial therapies to combat globally important drug-resistant human pathogens, including Plasmodium falciparum malarial parasites, Mycobacterium tuberculosis, and Gram-negative bacteria, including Escherichia coli. These organisms all possess the essential methylerythritol phosphate (MEP) pathway of isoprenoid biosynthesis, which is not found in humans. The first dedicated enzyme of the MEP pathway, 1-deoxy-d-xylulose 5-phosphate reductoisomerase (Dxr), is inhibited by the phosphonic acid antibiotic fosmidomycin and its analogs, including the N-acetyl analog FR900098 and the phosphoryl analog fosfoxacin. In order to identify mutations in dxr that confer resistance to these drugs, a library of E. coli dxr mutants was screened at lethal fosmidomycin doses. The most resistant allele (with the S222T mutation) alters the fosmidomycin-binding site of Dxr. The expression of this resistant allele increases bacterial resistance to fosmidomycin and other fosmidomycin analogs by 10-fold. These observations confirm that the primary cellular target of fosmidomycin is Dxr. Furthermore, cell lines expressing Dxr-S222T will be a powerful tool to confirm the mechanisms of action of future fosmidomycin analogs.
Activation of ERK and NF-κB during HARE-Mediated Heparin Uptake Require Only One of the Four Endocytic Motifs

Fifteen different ligands, including heparin (Hep), are cleared from lymph and blood by the Hyaluronan (HA) Receptor for Endocytosis (HARE; derived from Stabilin-2 by proteolysis), which contains four endocytic motifs (M1-M4). Endocytosis of HARE•Hep complexes is targeted to coated pits by M1, M2, and M3 (Pandey et al, Int. J. Cell Biol. 2015, article ID 524707), which activates ERK1/2 and NF-κB (Pandey et al J. Biol. Chem. 288, 14068–79, 2013). Here, we used a NF-κB promoter-driven luciferase gene assay and cell lines expressing different HARE cytoplasmic domain mutants to identify motifs needed for Hep-mediated signaling. Deletion of M1, M2 or M4 singly had no effect on Hep-mediated ERK1/2 activation, whereas signaling (but not uptake) was eliminated in HARE(ΔM3) cells lacking NPLY2519. ERK1/2 signaling in cells expressing WT HARE(Y2519A) or HARE(Y2519A) lacking M1, M2 and M4 (containing M3-only) was decreased by 75% or eliminated, respectively. Deletion of M3 (but not M1, M2 or M4) also inhibited the formation of HARE•Hep•ERK1/2 complexes by 67%. NF-κB activation by HARE-mediated uptake of Hep, HA, dermatan sulfate or acetylated LDL was unaffected in single-motif deletion mutants lacking M1, M2 or M4. In contrast, cells expressing HARE(ΔM3) showed loss of HARE-mediated NF-κB activation during uptake of each of these four ligands. NF-κB activation by the four signaling ligands was also eliminated in HARE(Y2519A) or HARE(M3-only;Y2519A) cells. We conclude that the HARE NPLY2519 motif is necessary for both ERK1/2 and NF-κB signaling and that Tyr2519 is critical for these functions.
An efficient and low cost monitoring system to improve availability and reliability of grid services

In the Grid and cloud computing systems, resources are shared among a large number of applications and users. These systems, as efficient environments, can be used for execution of long-running distributed applications. The failure occurrence during critical long-running applications can lead to spend considerable time and cost. This paper proposes an efficient job and resource monitoring services to attain the needed degree of availability and reliability of long-life application. In addition to the quality of services, the other focus of this work is to minimize resource consumption and the cost of requested services in the economic grid. The dynamic nature of proposed monitoring service leads to improve the availability and reliability of grid resources/services with low resource consumption. Analytical approach (Markov approach) is used to analyze the effect of our service on the availability and reliability of grid services/resources in the presence of permanent and transient faults.
Basolateral to apical transcytosis in polarized cells is indirect and involves BFA and trimeric G protein sensitive passage through the apical endosome

We have used temperature and nocodazole blocks in an in vivo basolateral to apical transcytosis assay to dissociate the early transcytotic steps occurring during the formation of transcytotic vesicles and their microtubule-dependent translocation into the apical region, from the late steps when transcytotic cargo is delivered into the apical media. We found that polarized MDCK cells transfected with rabbit polymeric IgA receptor (pIgA-R) internalize basolaterally added pIgA-R ligand ([Fab]2 fragment of IgG against the receptor's ectodomain) at 17 degrees C but do not deliver it to the apical PM. Instead, the ligand accumulates in an apically localized transcytotic compartment, distal to the basolateral endosome and the microtubule- requiring translocation step. We have characterized this compartment and show that it is distinct from basolateral transferrin recycling endosomes, basolateral early endosomes or late endosomes or lysosomes. The apical transcytotic compartment colocalizes with the compartment containing apically recycling membrane markers (ricin and apically internalized pIgA-R ligand) but is distinct from the compartment receiving apically internalized fluid phase marker (BSA). This compartment is an intermediate station of the overall pathway since transcytotic ligand can exit the compartment and be released into the apical medium when cells preloaded at 17 degrees C are subsequently incubated at 37 degrees C. We have used this system to examine the effect of Brefeldin A (BFA) and the involvement of trimeric GTPases in the late (post apical transcytotic compartment) steps of the transcytotic pathway. We found that addition of BFA or cholera toxin, a known activator of Gs alpha, to cells preloaded with transcytotic ligand at 17 degrees C significantly inhibits the exit of ligand from the apical transcytotic compartment. General structure and function of the apical endosome are not affected since neither BFA nor cholera toxin inhibit the recycling of apically internalized membrane markers (ricin and pIgA-R ligand) from the same compartment. The data suggest that transcytosis connects the "membrane-sorting" sub-domain of the basolateral endosome with a homologous sub-domain of the apical endosome and that exit of transcytosing cargo from the apical endosome is controlled by a BFA and trimeric G protein sensitive mechanism, distinct from that used for recycling of apically internalized proteins (ricin or pIgA-R).
A K-band high-gain down-converter mixer using cross couple pair active load

In this paper, we present a high-gain and wideband Gilbert cell mixer at K-band using PMOS cross couple pair as an active load. To avoid latch-up problem, we paralleled low resistor (2RLoad) at cross couple pair. We also use transimpedance amplifier to transfer impedance and drive high impedance circuit at next stage, such as ADC and OPA. The proposed mixer achieves 24 dB peak voltage conversion gains under 1 MΩ load and 7 GHz 3-dB bandwidth. From 20 to 30 GHz, the RF-to-LO and LO-to-RF isolations are better than 33 dB. The DC power consumption was only 17 mW for 1.8-V supply voltage. Compared with other CMOS design, this mixer shows higher conversion gain, wide bandwidth and compact area.
Exemplar activation and interpersonal behavior

This study investigates the effects of exemplar activation on the verbal responses of participants. Two-hundred people were sent a clearly miss-addressed e-mail message. The name of the sender was manipulated so that he could have the same name as a famous positive exemplar or as a famous negative exemplar. Replies (15%) showed no effect on the number of responses. However, effects emerged on the content of the responses. Overall, participants were much more friendly when the sender had the same name as a positive exemplar. Thus, it is demonstrated that assimilation effects might occur when a social target shares some irrelevant feature (i.e., the name) with a famous exemplar. Results are consistent with recent models that underlie the importance of exemplar activation on social perception and behavior. [33] --------------[34]
PERAN KEPEMIMPINAN ETIS DAN PEMBERDAYAAN PSIKOLOGI TERHADAP KEPUASAN UNTUK MENIINGKATKAN KINERJA ATLET PPLP SULAWESI TENGGARA

The purpose of this study is to examine and obtain empirical evidence of a significant effect of ethical leadership and psychological empowerment on satisfaction PPLP athletes Southeast Sulawesi , to examine and obtain empirical evidence of the significance of the influence of ethical leadership and psychological empowerment on the performance of athletes PPLP Southeast Sulawesi and to find the significance of the effect of satisfaction work on the performance of athletes PPLP Southeast Sulawesi . Problems in the lift in this study were 1 ) How does the performance athlete Ethical Leadership Southeast Sulawesi PPLP 2 ) How PsychologicalEmpowerment influence on performance ( achievement ) Athletes PPLP Southeast Sulawesi 3 ) How does Ethical Leadership on Job Satisfaction Athletes PPLP Southeast Sulawesi 4 ) how to influence Psychology Empowerment on Job Satisfaction Athletes PPLP Southeast Sulawesi 5 ) how does Job Satisfaction to Performance ( achievement ) Athletes PPLP Southeast Sulawesi.The research was conducted on athletes PPLP Southeast Sulawesi . Data was collected by questionnaire and literature with a number sampel to many 90 respondents consisting of 11 female respondents and 79 male respondents . The data analysis technique used is the Patrial Least Square (PLS) analysis is a powerful metoode therefore does not assume the data to be certain scale data, not need many assumptions and sample size should not be large . The results showed that ethical leadership variable had no significant effect on performance , psychologicalempowerment have a significant effect on performance , ethical leadership significant effect on satisfaction, psychological empowerment significant effect on satisfaction, and satisfaction have a significant effect on performance.Keywords : Ethical Leadership, Phsycological Empowertment, Satisfaction and Performance.
Creative Movement Dance Class for Adolescents with Autism Spectrum Disorder

1 Objective: The objective of this phenomenological study was to identify how an occupational 2 therapy developed Creative Movement Dance Class (CMDC) addresses social interaction skills 3 in adolescents with Autism Spectrum Disorder (ASD). 4 Method: Interviews were conducted with a Certified Occupational Therapist Assistant (COTA), 5 Occupational Therapist (OT), ballet instructor, student intern, teacher, and an aide that were 6 directly involved with the CMDC. 7 Results: Three themes were identified. The first theme, structure of the class, consisted of eight 8 sub-themes including opportunity to practice, fulfilling sensory needs, the Just Right Challenge, 9 classroom support, classroom expectations, interprofessional collaboration, themes, and format 10 of the class. The second theme, engagement techniques, consisted of five sub-themes including 11 peer modeling, turn taking, use of props, making choices, and coping skills. The third theme, 12 teaching techniques, consisted of four sub-themes including instructors body positioning, 13 verbal/physical/visual cues, instructor modeling, and communication (sentence strips, Personal 14 Exchange Communication System [PECS], and core vocabulary). 15 Conclusion: An occupational therapy developed CMDC addresses social interaction skills 16 through the structure of the class, engagement techniques, and teaching techniques. Many of the 17 techniques identified are supported in the literature for ASD and creative movement. Several 18 novel techniques were found that may prove to be effective in addressing social interaction skills 19 for adolescents with ASD through a CMDC. 20 MeSH terms 21 Adolescents, Autism Spectrum Disorder, Creative Movement, Dance, Social Skills 22
Calibration of a polarimetric radar using a rotatable dihedral corner reflector

Based on the existing mathematical formalisms of radar polarimetry, it is necessary to perform accurate and diversified polarimetric measurements in the real world to thoroughly investigate signature definition, identification, and classification of radar targets. For this study the Delft Atmospheric Research Radar (DARR) is used. This ground-based polarimetric FM-CW radar operates in the S-band. The purpose of the present paper is the polarimetric calibration of the DARR. Among the passive reflectors, a rotatable dihedral corner reflector is a suitable calibration object. It enables one to measure different scattering matrices with only one reflector. One alignment must be performed and the scattering matrices are measured at the same range. By measuring several scattering matrices, the accuracy of the calibration result can be estimated. A measurement campaign with a rotatable dihedral corner reflector was therefore performed. The experimental results and the calibration procedure are presented in this paper. >
Learning attentional policies for tracking and recognition in video with deep networks

We propose a novel attentional model for simultaneous object tracking and recognition that is driven by gaze data. Motivated by theories of the human perceptual system, the model consists of two interacting pathways: ventral and dorsal. The ventral pathway models object appearance and classification using deep (factored)-restricted Boltzmann machines. At each point in time, the observations consist of retinal images, with decaying resolution toward the periphery of the gaze. The dorsal pathway models the location, orientation, scale and speed of the attended object. The posterior distribution of these states is estimated with particle filtering. Deeper in the dorsal pathway, we encounter an attentional mechanism that learns to control gazes so as to minimize tracking uncertainty. The approach is modular (with each module easily replaceable with more sophisticated algorithms), straightforward to implement, practically efficient, and works well in simple video sequences.
Impaired Cognitive Executive Dysfunction in Adult Treated Hypertensives with a Confirmed Diagnosis of Poorly Controlled Blood Pressure

Background. High blood pressure (BP) poses a major risk for cognitive decline. Aim of the study was to highlight the relationship between cognitive assessment scores and an effective therapeutic BP control. Methods. By medical visit and ambulatory BP monitoring (ABPM), we studied 302 treated hypertensives, subdivided according to office/daytime BP values into 120 with good (GC) and 98 poor (PC) BP control, 40 with “white coat hypertension” (WCH) and 44 a “masked-hypertension” phenomenon (MH). Patients underwent neuropsychological assessment to evaluate global cognitive scores at the Mini Mental State Examination (MMSE) and Frontal Assessment Battery (FAB) and attention/executive functions (Delayed Recall, Digit Span Forwards, Digit Span Backwards, Selective Attention, Verbal Fluency, Stroop Test and Clock Drawing). Carotid intima-media thickness (IMT) served as the index of vascular damage. Results. There were no differences among the groups in terms of gender, age, education, metabolic assessment, clinical history and hypertension treatment. GC presented lower office and ambulatory BP values and IMT. PC performed worse than GC on global executive and attention functions, especially executive functions. In PC, office systolic BP (SBP) was significantly associated to the MMSE and FAB scores and, in particular, to Verbal Fluency, Stroop Errors and Clock Drawing tests. Office diastolic BP (DBP) was associated to Selective attention, nocturnal SBP to Digit Span backwards and Verbal Fluency. Worse cognitive assessment scores were obtained in WCH than GC. Conclusions. The findings showed that in adult treated hypertensives, a poor BP control, as both doctor's office and daytime scores, is associated to impaired global cognitive and especially executive/attention functions.