Miracle-dz/UniFAR-FTUs huggingface dataset:
Divorce: Causes and Consequences

This comprehensive book provides a balanced overview of the current research on divorce. The authors examine the scientific evidence to uncover what can be said with certainty about divorce and what remains to be learned about this socially and politically charged issue. Accessible to parents and teachers as well as clinicians and researchers, the volume examines the impact of marital breakup on children, adults, and society. Alison Clarke-Stewart and Cornelia Brentano synthesize the most up-to-date information on divorce from a variety of disciplinary perspectives with thoughtful analysis of psychological issues. They convey the real-life consequences of divorce with excerpts from autobiographies by young people, and they also include guidelines for social policies that would help to diminish the detrimental effects of divorce.
Transcriptional Profiling of Bone Regeneration

The healing of skeletal fractures is essentially a replay of bone development, involving the closely regulated, interdependent processes of chondrogenesis and osteogenesis. Using a rat femur model of bone healing to determine the degree of transcriptional complexity of these processes, suppressive subtractive hybridization (SSH) was performed between RNA isolated from intact bone to that of callus from post-fracture (PF) days 3, 5, 7, and 10 as a means of identifying up-regulated genes in the regenerative process. Analysis of 3,635 cDNA clones revealed 588 known genes (65.8%, 2392 clones) and 821 expressed sequence tags (ESTs) (31%, 1,127). The remaining 116 cDNAs (3.2%) yielded no homology and presumably represent novel genes. Microarrays were then constructed to confirm induction of expression and determine the temporal profile of all isolated cDNAs during fracture healing. These experiments confirmed that ∼90 and ∼80% of the subtracted known genes and ESTs are up-regulated (≥2.5-fold) during the repair process, respectively. Clustering analysis revealed subsets of genes, both known and unknown, that exhibited distinct expression patterns over 21 days (PF), indicating distinct roles in the healing process. Additionally, this transcriptional profiling of bone repair revealed a host of activated signaling molecules and even pathways (i.e. Wnt). In summary, the data demonstrate, for the fist time, that the healing process is exceedingly complex, involves thousands of activated genes, and indicates that groups of genes rather than individual molecules should be considered if the regeneration of bone is to be accelerated exogenously.
Traumatic Responding in Children Exposed to Domestic Violence

Abstract The present cross-cultural study summarizes the traumatic responses of Mexican, Mexican American, and non-Mexican American children who were residents of three shelters for battered women in Monterrey Mexico, McAllen Texas, and Ft. Worth Texas. Sixty-eight mothers reported on their children's (n = 90) individual and total traumatic symptoms. Findings revealed very slight differences in individual responses with no overall trauma symptom differences. Multiple regression analyses revealed that mothers' experiences of physical, and sexual abuse predicted greater trauma responses in children. Implications for practice with children and mothers in shelters for battered women are highlighted.
Prognosis of schizophrenia in persons with and without a history of cannabis use

Background The aim of the study was to determinate whether schizophrenia patients with a history of cannabis use have a different prognosis, with regards to readmission and hospital duration, compared with those without a history of cannabis use. Method The present investigation was a cohort study of 50 087 Swedish men with data on cannabis use at the ages of 18–20 years. A total of 357 cases of schizophrenia were identified from in-patient care and followed up from 1973 to 2007. Results Schizophrenia patients with a history of cannabis use had a higher median duration of first hospital episode (59 days v. 30 days). Patients with a history of cannabis use had a higher median rate of readmission (10 times v. four times). Also, total number of hospital days was higher in patients with a history of cannabis use compared with those without (547 days v. 184 days). Patients with a history of cannabis use had an increased odds of having more than 20 hospital readmissions compared with non-users [3.1, 95% confidence interval (CI) 1.3–7.3] as well as an increased odds of hospital admission lasting more than 2 years (2.4, 95% CI 1.1–7.4) after controlling for diagnosis of personality disorders, family socio-economic position, IQ score, civil status, place of residence, risky use of alcohol and use of other drugs. Patients with a history of cannabis use were less likely to have paranoid schizophrenia compared with never users (8% v. 17%) in the first admission. Conclusions Schizophrenia patients with a history of cannabis use had a significantly higher burden of lifetime in-patient care than non-cannabis users. Not only does cannabis increase the risk of schizophrenia, but also our findings indicate that the course and prognosis of schizophrenia may be more severe than schizophrenia cases in general.
Endocannabinoids Link Feeding State and Auditory Perception-Related Gene Expression

Singing by adult male zebra finches is a learned behavior important for courtship, kin recognition, and nest defense (Zann, 1996) and is inhibited by both brief periods of limited food availability and systemic injection of cannabinoids. These similar effects on singing, combined with increasing evidence for endocannabinoid involvement in feeding behavior, led us to evaluate a possible shared mechanism. We found that limited food availability both reduces singing in a cannabinoid antagonist-reversible manner and increases levels of the endocannabinoid 2-arachidonyl glycerol in various brain regions including the caudal telencephalon, an area that contains auditory telencephalon including the L2 subfield of L (L2) and caudal medial nidopallium (NCM). Development and use of an anti-zebra finch cannabinoid receptor type 1 (CB1) antibody demonstrates distinct, dense cannabinoid receptor expression within song regions including Area X, lMAN (lateral magnocellular nucleus of anterior nidopallium), HVC, RA (robust nucleus of arcopallium), and L2. NCM receives L2 projections and is implicated in integration of auditory information. Activity in this area, determined through expression of the transcription factor ZENK, is increased after exposure to unfamiliar song. Because previous work has shown that these novel song-stimulated increases in NCM activity are mitigated by cannabinoid exposure, we tested and found that similar effects on ZENK expression are produced by limiting food. Limited food-related reductions in the activity of NCM neurons were reversed by the cannabinoid antagonist SR141716A (N-piperidino-5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methylpyrazole-3-carboxamide), implicating CB1 cannabinoid receptor involvement. Taken together, these experiments indicate a link between feeding state and gene expression related to auditory perception that is mediated by endocannabinoid signaling.
Brand Memory, Attitude, and State Aggression in Violent Games: Focused on the Roles of Arousal, Negative Affect, and Spatial Presence

Violent games have increasingly gained their market share in recent video game markets. They have attracted much attention due to their potential effects on users in advertising and aggression. However, little research has investigated such effects considering both user aggression and persuasion mechanism in virtual space. Based on the general aggression model and the presence theory, the current study examines the effects of realistic violence cues (blood and screams) and trait aggression on brand memory, attitude change toward brands in the game, and state aggression through physiological arousal (i.e., Skin conductance level), negative affect and spatial presence. Results show that violence cues affect both arousal and negative affect, and in turn the negative affect changes attitude toward brands negatively and increases the degree of state aggression. Trait aggression enhances presence, and the spatial presence strongly affects brand memory. Results and implications are discussed.
Efficacy of 2 Drops versus 3 Drops Proparacaine 0.5% Ophthalmic Solution for Phacoemulsification Surgery: A Comparative Study

Background and Aim: Phacoemulsification surgery with intraocular lens implantation is routinely done under topical anaesthesia in many centres. No comparative study on the efficacy of number of drops of topical anaesthetics effective for phacoemulsification surgery has been done. This study was conducted to compare the efficacy of 2 drops versus 3 drops proparacaine 0.5% ophthalmic solution for phacoemulsification surgery. Methods: Patients with uncomplicated cataract undergoing phacoemulsification surgery were randomised into two groups. Group 1 (n = 53) received 3 drops of proparacaine 0.5% whereas group 2 (n = 47) received 2 drops of the same solution before the start of surgery. All the patients underwent phacoemulsification with foldable intraocular lens implantation. Each patient’s subjective experience of pain was measured using a 10 point Visual Analogue Pain Scale (VAS). Patient’s cooperation during the surgery was assessed using a 3 point score. Both the evaluating resident doctor and patients were blinded. Results: In group 1, 73.6% patients scored 0, 20.8% scored 1 and 5.7% scored 2 of VAS respectively and in group 2, 89.4%, 6.4%, 4.3% patients scored 0, 1 and 2 of VAS respectively. In patient cooperation, 90.1% and 9.4% patients in group 1 scored 1 and 2 respectively whereas 87.2% and 12.8% patients scored 1 and 2 respectively in group 2. No statistically significant difference in the mean VAS (P = 0.0.55) and patient cooperation score (P = 0.597) was found between the two groups. The mean VAS score was 1.24 ± 0.534 and the mean patient cooperation score was 1.11 ± 0.314. The mean total surgical time was 25.11 ± 2.68 minutes. No additional drops were required for either group. Conclusions: Topical anaesthesia with both 2 drops and 3 drops proparacaine 0.5% ophthalmic solution is effective for phacoemulsification with intraocular lens implantation. Additional anaesthesia may be unnecessary in these cases.
Ontology-aware partitioning for knowledge graph identification

Knowledge graphs provide a powerful representation of entities and the relationships between them, but automatically constructing such graphs from noisy extractions presents numerous challenges. Knowledge graph identification (KGI) is a technique for knowledge graph construction that jointly reasons about entities, attributes and relations in the presence of uncertain inputs and ontological constraints. Although knowledge graph identification shows promise scaling to knowledge graphs built from millions of extractions, increasingly powerful extraction engines may soon require knowledge graphs built from billions of extractions. One tool for scaling is partitioning extractions to allow reasoning to occur in parallel. We explore approaches which leverage ontological information and distributional information in partitioning. We compare these techniques with hash-based approaches, and show that using a richer partitioning model that incorporates the ontology graph and distribution of extractions provides superior results. Our results demonstrate that partitioning can result in order-of-magnitude speedups without reducing model performance.
An overview of exposure to ethanol-containing substances and ethanol intoxication in children based on three illustrated cases

Alcohol addiction and intoxication are major health problems worldwide. Acute alcohol intoxication is well reported in adults and adolescents but less frequently reported in children of younger ages. We report three anonymized cases of pediatric ethanol exposure and illustrate the different mechanisms of intoxication. In all cases, a focused history is the key to prompt diagnosis and timely management. Physicians should be aware of this potential poison in children presented with acute confusional or encephalopathic state. In contrast, neonates with ethanol intoxication may present with nonspecific gastrointestinal symptomatology. Urgent exclusion of sepsis, electrolyte imbalance, drug intoxication, and surgical abdominal condition is critical. Using these illustrated cases, we performed a narrative literature review on issues of exposure to ethanol-containing substances and ethanol intoxication in children. In conclusion, a high level of suspicion and interrogation on ethanol or substance use are essential particularly in the lactating mother for an accurate and timely diagnosis of ethanol intoxication to be made.
Principles of cyberbullying research: definitions, measures, and methodology

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Cochlear Implants in Elderly People: Preliminary Results

The objective of this study was to evaluate the benefit of cochlear implantation in adults aged 60 years and over. Twenty-eight patients, older than 60 years and with profound bilateral sensorineural hearing loss, received a cochlear implant between 1991 and 2001. The mean age was 66 years and the median follow-up was 22.5 months. Speech perception scores before and after implantation were analyzed retrospectively in order to evaluate the benefit of cochlear implantation. There was a significant improvement of the disyllabic words and sentences scores after implantation. The patients who were over 70 years performed as well as those who were younger. The surgical procedure was well tolerated in all patients. One patient developed a postoperative vertigo due to a perilymphatic fistula. In conclusion, cochlear implantation offers improvement in speech perception to the elderly population, as in the younger population. A careful assessment of the physical status of these patients remains essential in order to evaluate the risk–benefit of this procedure.
Hypertension and left ventricular hypertrophy in autosomal dominant polycystic kidney disease

Hypertension is a common problem in patients with autosomal dominant polycystic kidney disease affecting both renal and patient survival. Activation of the renin–angiotensin–aldosterone system due to cyst expansion and local renal ischemia has been proposed to play an important role in the development of hypertension in autosomal dominant polycystic kidney disease. Left ventricular hypertrophy, a major cardiovascular risk factor, is also common in patients with autosomal dominant polycystic kidney disease. Both hypertension and the activation of the renin–angiotensin–aldosterone system play a role in the development of left ventricular hypertrophy in these patients. Prospective randomized results indicate that aggressive control of blood pressure is important for the optimal reversal of left ventricular hypertrophy, thereby diminishing a major risk factor for cardiovascular morbidity and mortality of patients with autosomal dominant polycystic kidney disease. There is also substantial epidemiological support for aggressive control of blood pressure in slowing renal disease progression in autosomal dominant polycystic kidney disease patients. Blockade of the renin–angiotensin–aldosterone system should be the initial approach in the treatment of hypertension in these patients.
The role of mothers in the social development of their infants' facial expressions.

The present thesis addresses the role of maternal interpretations of infant facial expressions in the development of emotions. Emotion theories explain emotionality in terms of implicitly intra-individual processes resulting in serious conceptual and empirical limitations. In contrast, social constructionist theories reflect the inherently socio-cognitive nature of emotions and propose inter-individual processes to explain emotional development. Using the hitherto neglected perspective of interactional others, a social theory is developed which rejects the Cartesian dualism inherent in current theories of emotional development by assigning a central place to the perspective of caregivers in the development of emotions. An observational cross-sectional study examining the effect of age and context on mothers' perceptions of their infants was conducted. Twelve normal, primiparous, white, English, middle class mothers, aged between 25 and 35, were filmed interacting at home with their infants (aged 4-6 months (range 4;l-6;3), 7-9 months (range 7;0-9;l), and 10-12 months (range 10;1-11;3)). Mothers were asked to select and describe infant acts they found meaningful in a face to face play, a prohibitive, and a toy play condition. Facial expressions were coded using a standardised coding frame. Maternal interpretations of infant behaviour were collected and analysed. Two further experiments assessed differences between mothers' and observers' selections and interpretations of infant behaviour. Mothers' selections of infant facial expressions differed between age groups and situations. As infants got older, mothers selected fewer positive expressions in face to face play, more negative expressions in the prohibitive episode and more positive expressions in toy play. Differences in maternal interpretations, reflecting situational and age related specificity, were also found. While mothers perceived emotions and intentionality in infants of all ages, mothers of the oldest infants accompanied these attributions with descriptions of cognitive and communicative skills. A relationship between selected facial expressions and attributions of emotion states was found to be dependent on situational context. Mothers also differed from observers in both the number of meaningful acts they selected and the types of interpretations they made, demonstrating the divergence in perspective between caretakers as knowledgable participants in interaction and external observers. This thesis demonstrates the dynamics of caregivers' perceptions in expressive interaction and discusses the implications of these perceptions for understanding the process of emotional development.
Análisis sistémico en la generación cultural de una comunidad virtual de aprendizaje Systemic Analysis of the Cultural Production of a Virtual Learning Community

This paper describes a systemic analysis from the standpoint of activity theory of the cultural emergence of a virtual learning community as a complex system. Three levels of analysis were employed: data mining, visualization of complex systems and analysis of discursive interactions, with the aim of understanding the emerging phenomena of online learning and in order to have the necessary elements to assist in planning the formation of virtual communities in formal settings. This was carried out using six years of activity from 3,324 people from different documentary sources: 9,871,531 CMS records; 1,371,907 from LMS; 67,828 IRC statements; and 27,798 online forum comments. In the process, we observed how action aimed at socialization and discussion of its object evolve into historical-cultural milestones such as the culture of merit as opposed to certification, the division of labor and the process of transition from free software to free culture.
Mixture regression for observational data, with application to functional regression models

In a regression analysis, suppose we suspect that there are several heterogeneous groups in the population that a sample represents. Mixture regression models have been applied to address such problems. By modeling the conditional distribution of the response given the covariate as a mixture, the sample can be clustered into groups and the individual regression models for the groups can be estimated simultaneously. This approach treats the covariate as deterministic so that the covariate carries no information as to which group the subject is likely to belong to. Although this assumption may be reasonable in experiments where the covariate is completely determined by the experimenter, in observational data the covariate may behave differently across the groups. Thus the model should also incorporate the heterogeneity of the covariate, which allows us to estimate the membership of the subject from the covariate. In this paper, we consider a mixture regression model where the joint distribution of the response and the covariate is modeled as a mixture. Given a new observation of the covariate, this approach allows us to compute the posterior probabilities that the subject belongs to each group. Using these posterior probabilities, the prediction of the response can adaptively use the covariate. We introduce an inference procedure for this approach and show its properties concerning estimation and prediction. The model is explored for the functional covariate as well as the multivariate covariate. We present a real-data example where our approach outperforms the traditional approach, using the well-analyzed Berkeley growth study data.
Reliability of Object Oriented Systems with Markov Transfer of Control

Object oriented systems are considered which can be decomposed into a finite number of objects. These systems are composed at runtime of interacting objects, residing in computer memory and holding the data to be processed. Every object is described in the realm of software by its class. So, at the architectural and language level, Object Oriented Systems are composed of classes, the basic object oriented building blocks. Each object has an associated reliability which gives the probability that the method will operate correctly when called by that object.
O aprendizado da utilização da substituição sensorial visuo-tátil por pessoas com deficiência visual: primeiras experiências e estratégias metodológicas

The tactile-vision-substitution-system (TVSS) is an assistive technology designed to aid the visually impaired in perceiving visual aspects of their environment located beyond touch. In order to better understand the learning process of that assistive aid, we trained four blind participants with the Brainport®, the last version of the TVSS, where the transformed visual images are explored by the tongue. More specifically, this article aims to investigate the initial stage of this learning process, in terms both of participants' performance and their qualitative experience. The training, conducted according to the clinical-pedagogic method, produced data both from the first-person and the third-person point of view. Data were gathered through records of participants' performance and explanation interviews. Results show that the main difficulties arising during the process concerned sensory-motor coupling, body and head movement, and the gap between actual and expected quality of the perceptual experience.