Miracle-dz/UniFAR-FTUs huggingface dataset:
Experimental assessment of ESS integration in a microgrid supplied by photovoltaic

In this paper the results of ten months monitoring of the microgrid supplied by the photovoltaic generator and operating in the Mediterranean area have been presented. The microgrid architecture and control strategy have been described. Further, the analysis of the energy exchange between the microgrid and the main grid have been analyzed. A particular attention has been given to the optimization of the renewable energy management as to power the microgrid loads and consequently, to increase the photovoltaic energy self — consumption rate. This was possible thanks to implementation of the energy storage system, coupled with the photovoltaic generator. The obtained results demonstrate the technical feasibility of the microgrid, pointing out how the introduction of the storage improves the photovoltaic energy management. Moreover, it has been shown how the microgrid improves the integration of the photovoltaic system with the main grid. The economic evaluation of the costs incurred for the development and maintenance of the microgrid has been carried out. The analysis has been reported also in terms of levelized cost of energy. The results show that the cost effectiveness of the microgrid is increasing with the system operation life time.
Early intervention in psychosis in developing coun‐tries: evidence and action

In the recent forum on early intervention for psychosis in World Psychiatry 1, Ndetei highlights the lack of progress in bringing about early intervention in psychosis in Africa, where more than 50% of the population is under the age of 25 2. Ndetei also points out that almost all the research about early intervention is conducted in developed countries. In our recent review of the duration of untreated psychosis (DUP) in low and middle income (LAMI) countries, we employed exhaustive search strategies, but were only able to locate data from 18 of over 150 LAMI and only 3 of over 50 African countries 3. The low priority given to mental health in LAMI countries 4, 8 and the widely accepted but controversial notion that schizophrenia carries a better prognosis in developing countries might have hindered the development of services for psychosis. We found that the average mean DUP in studies from LAMI countries was 125.0 weeks compared with 63.4 weeks in studies from high-income countries (p=0.012). Using the data on gross domestic product (GDP), we demonstrated that within the studies from LAMI countries, mean DUP fell by 6 weeks for every $1000 of GDP purchasing power parity. In a related paper, we reviewed the studies from LAMI countries that investigated an association between DUP and at least one of the following outcome measures: psychotic symptoms, cognitive function, social disability or mortality. The DUP in LAMI countries was significantly associated with higher ratings of positive symptoms and social disability, a finding similar to that reported in high-income countries 9. In addition, two studies 10, 11 suggest a strong association between DUP and subsequent mortality from physical illness. The “good prognosis” hypothesis seems less tenable when the high prevalence of partially and never treated cases of psychosis in developing countries and the long DUP for those who do receive treatment is taken into consideration. The adverse consequences of long DUP, and the increased morbidity and mortality from infections and malnutrition among those with mental illness, confirm the need for a vigorous approach to early intervention in developing countries. This approach, however, needs to take social and economic realities of developing countries into account. One of the interventions could be to pro-vide antipsychotic treatment free of cost at least for the initial two years, the “critical period” in the course of schizophrenia, as the cost of the drugs appears to be the main barrier to access the treatment. This could be under the supervision of a close relative who is trained to supervise and monitor the patient medication, with the patient’s consent 12. The development of early intervention in psychosis services in LAMI countries faces formidable obstacles. However, the seri-ously mentally ill in LAMI regions are among the most disadvantaged people on earth. Making treatment available is a moral neces-sity and providing early treatment is likely to be cost-effective.
Multiple Lines of Evidence Localize Signaling, Morphology, and Lipid Biosynthesis Machinery to the Mitochondrial Outer Membrane of Arabidopsis[W][OA]

The composition of the mitochondrial outer membrane is notoriously difficult to deduce by orthology to other organisms, and biochemical enrichments are inevitably contaminated with the closely associated inner mitochondrial membrane and endoplasmic reticulum. In order to identify novel proteins of the outer mitochondrial membrane in Arabidopsis (Arabidopsis thaliana), we integrated a quantitative mass spectrometry analysis of highly enriched and prefractionated samples with a number of confirmatory biochemical and cell biology approaches. This approach identified 42 proteins, 27 of which were novel, more than doubling the number of confirmed outer membrane proteins in plant mitochondria and suggesting novel functions for the plant outer mitochondrial membrane. The novel components identified included proteins that affected mitochondrial morphology and/or segregation, a protein that suggests the presence of bacterial type lipid A in the outer membrane, highly stress-inducible proteins, as well as proteins necessary for embryo development and several of unknown function. Additionally, proteins previously inferred via orthology to be present in other compartments, such as an NADH:cytochrome B5 reductase required for hydroxyl fatty acid accumulation in developing seeds, were shown to be located in the outer membrane. These results also revealed novel proteins, which may have evolved to fulfill plant-specific requirements of the mitochondrial outer membrane, and provide a basis for the future functional characterization of these proteins in the context of mitochondrial intracellular interaction.
Chaotic Cooperative Particle Swarm Optimization Based on Tent Map

In this paper, a chaotic cooperative particle swarm optimization based on Tent map (TCCPSO) is proposed. The cooperative particle swarm optimization (CPSO), can significantly improve the performance of the original algorithm. However, CPSO has the defect of leading to pseudominimizer, which can not be easily escaped by interleaving the CPSO and PSO algorithm. Therefore, we take full advantages of the characteristics of ergodicity and randomness of chaotic variables to help the particles escape from pseudominimizer and converge to global optimum. The experimental results on some benchmark functions show that TCCPSO outperforms the CPSO. In addition, simulation results show that algorithm computation precision is increased and that the algorithm convergence is improved. Keywords—particle swarm optimization; chaotic mutation; cooperative particle swarm optimization
Prediction with expert advice for the Brier game

We show that the Brier game of prediction is mixable and find the optimal learning rate and substitution function for it. The resulting prediction algorithm is applied to predict results of football and tennis matches. The theoretical performance guarantee turns out to be rather tight on these data sets, especially in the case of the more extensive tennis data.
Accumulation of SOC under organic and no-fertilizations, and its influence on crop yields in Tanzania’s semiarid zone

ABSTRACT Introduction: To estimate differential accumulation of soil organic carbon (SOC) and its ecological significance is very important to smallholder farmers in the Tanzania’s semiarid areas. This study investigated the accumulation of SOC and other important soil nutrients under organic and no-fertilizations, and correlated SOC with crop yields. Using data from long-term experimental study sites of semiarid in Tanzania, we estimated SOC accumulation in different soil treatments and depths where a total of 128 soil samples were collected at the depths of 0–20 cm and 20–40 cm from two villages (sites) with organic fertilization and no-fertilization treatments. Sites under organic fertilization were defined as those which have received manure fertilization for more than 5 years on continuum basis. Outcomes: The accumulation of SOC was significantly greater in soils under organic fertilizations (1.15 and 0.80 MgC ha−1 at soil depth and 20–40 cm) and decreased with increasing soil depths. Similarly, TN and P decreased from 0.40 and 2.40 Mg (0–20 cm) to 0.16 and 2.10 Mg (20–40 cm), respectively. Other important soil nutrients such as calcium (Ca2+), potassium (K+), magnesium (Mg2+), and sodium (Na+) had similar pattern. In addition, soil bulk density was less under organic fertilization (1.1 g/cm3) than under no-fertilization (1.2 g/cm3) and it increased with soil depths. Correspondingly, the crop yields were significantly higher (1.6 tn ha−1) under organic fertilizations than (0.6 tn ha−1) under no-fertilizations indicating that crop yields were significantly affected by SOC. Discussion: Organic fertilization i.e., especially cattle manure in the area has considerable fertility potential. To optimize soil fertility potential, we need to consider such kind of fertilization from household to national level. Conclusion: Our results demonstrated that manure application was the best fertilization method for improving soil fertility in most croplands of Tanzania’s semiarid areas, especially in this era of climate change scenarios.
Achalasia: a systematic review.

IMPORTANCE Achalasia significantly affects patients' quality of life and can be difficult to diagnose and treat. OBJECTIVE To review the diagnosis and management of achalasia, with a focus on phenotypic classification pertinent to therapeutic outcomes. EVIDENCE REVIEW Literature review and MEDLINE search of articles from January 2004 to February 2015. A total of 93 articles were included in the final literature review addressing facets of achalasia epidemiology, pathophysiology, diagnosis, treatment, and outcomes. Nine randomized controlled trials focusing on endoscopic or surgical therapy for achalasia were included (734 total patients). FINDINGS A diagnosis of achalasia should be considered when patients present with dysphagia, chest pain, and refractory reflux symptoms after an endoscopy does not reveal a mechanical obstruction or an inflammatory cause of esophageal symptoms. Manometry should be performed if achalasia is suspected. Randomized controlled trials support treatments focused on disrupting the lower esophageal sphincter with pneumatic dilation (70%-90% effective) or laparoscopic myotomy (88%-95% effective). Patients with achalasia have a variable prognosis after endoscopic or surgical myotomy based on subtypes, with type II (absent peristalsis with abnormal pan-esophageal high-pressure patterns) having a very favorable outcome (96%) and type I (absent peristalsis without abnormal pressure) having an intermediate prognosis (81%) that is inversely associated with the degree of esophageal dilatation. In contrast, type III (absent peristalsis with distal esophageal spastic contractions) is a spastic variant with less favorable outcomes (66%) after treatment of the lower esophageal sphincter. CONCLUSIONS AND RELEVANCE Achalasia should be considered when dysphagia is present and not explained by an obstruction or inflammatory process. Responses to treatment vary based on which achalasia subtype is present.
Identifying the Information Gain of a Quantum Measurement

We show that quantum-to-classical channels, i.e., quantum measurements, can be asymptotically simulated by an amount of classical communication equal to the quantum mutual information of the measurement, if sufficient shared randomness is available. This result generalizes Winter's measurement compression theorem for fixed independent and identically distributed inputs to arbitrary inputs, and more importantly, it identifies the quantum mutual information of a measurement as the information gained by performing it, independent of the input state on which it is performed. Our result is a generalization of the classical reverse Shannon theorem to quantum-to-classical channels. In this sense, it can be seen as a quantum reverse Shannon theorem for quantum-to-classical channels, but with the entanglement assistance and quantum communication replaced by shared randomness and classical communication, respectively. The proof is based on a novel one-shot state merging protocol for classically coherent states as well as the postselection technique for quantum channels, and it uses techniques developed for the quantum reverse Shannon theorem.
Small Molecule Inhibitors of Human Papillomavirus Protein - Protein Interactions

Human papillomaviruses (HPV) have now been identified as a necessary cause of benign and malignant lesions of the differentiating epithelium, particularly cervical cancer, the second most prevalent cancer in women worldwide. While two prophylactic HPV vaccines and screening programs are available, there is currently no antiviral drug for the treatment of HPV infections and associated diseases. The recent progress toward the identification and characterization of specific molecular targets for small molecule-based approaches provides prospect for the development of effective HPV antiviral compounds. Traditionally, antiviral therapies target viral enzymes. HPV encode for few proteins, however, and rely extensively on the infected cell for completion of their life cycle. This article will review the functions of the viral E1 helicase, which encodes the only enzymatic function of the virus, of the E2 regulatory protein, and of the viral E6 and E7 oncogenes in viral replication and pathogenesis. Particular emphasis will be placed on the recent progress made towards the development of novel small molecule inhibitors that specifically target and inhibit the functions of these viral proteins, as well as their interactions with other viral and/or cellular proteins.
Using Electrical Resistivity Tomography (ERT) to Delineate Subsurface Structures at Siloam Hot Spring in the Soutpansberg Basin, South Africa

Electrical resistivity tomography (ERT) was used to delineate subsurface structures at Siloam hot spring in the Soutpansberg Basin of South Africa. The spring water was reported to be hottest in South Africa. Groundwater with temperature ranging between 63.3 °C and 67.5°C was observed flowing from the spring. Relatively wet areas were noted to the south and north of the spring. Electrical resistivity arrays with Dipole-dipole and Wenner-Schlumberger configurations were used. Current injection and potential dipole separations of 5 m and 10 m were applied across the spring. Inversion results for arrays with the shorter dipole separation of 5 m had better resolution. Resistivity sections were generated from inversion of ERT data. The resistivity values for the low and high resistive zones were ρa < 10 and ρa > 70 Ωm respectively. Sub-horizontal resistivity zones were obtained from the inversion of Wenner-Schlumberger array survey data. High resistivity zones associated with dykes or sills were delineated on Dipole-dipole derived depth sections. Near vertical structures associated with water bearing faults or fractures were delineated at the Siloam hot spring.
Quality assured image file format migration in large digital object repositories

This article gives an overview on how different components developed by the SCAPE project are intended to be used in composite file format migration workflows; it will explain how the SCAPE platform can be employed to make sure that the workflows can be used to migrate very large image collections and in which way the integration with a digital object repository is intended. Two institutional image data migration scenarios are used to describe how the composite workflows could be applied in production library environments. The first one is related to the British Newspapers 1620-1900 project at the British Library which produced around 2 million images of newspaper pages in TIFF format. The second is a large digital book collection hosted by the Austrian National Library where the book page images are stored as JPEG2000 image files.
Interference management for CDMA systems through power control, multiuser detection, and beamforming

Among the ambitious challenges to be met by the third-generation systems is to provide high-capacity flexible services. Code-division multiple access (CDMA) emerges as a promising candidate to meet these challenges. It is well known that CDMA systems are interference-limited, and interference management is needed to maximally utilize the potential gains of this access scheme. Several methods of controlling and/or suppressing the interference through power control, multiuser detection (temporal filtering), and receiver beamforming (spatial filtering) have been proposed to increase the capacity of CDMA systems up to date. We investigate the capacity increase that is possible by combining power control with intelligent temporal and spatial receiver filter design. The signal-to-interference ratio maximizing joint temporal-spatial receiver filters in unconstrained and constrained filter spaces are derived. Two-step iterative power control algorithms that converge to the optimum powers and the joint temporal and spatial receiver filters in the corresponding filter domains are given. A power control algorithm with a less complex filter update procedure is also given. We observe that significant savings in total transmit power are possible if filtering in both domains is utilized compared with conventional power control and joint optimal power control and filtering in only one domain.
Assessing the Health Impact of Water Quality Interventions in Low-Income Settings: Concerns Associated with Blinded Trials and the Need for Objective Outcomes

Background: A dramatic disparity between the results of blinded versus open trial designs has raised questions about the effectiveness of water quality interventions and other environmental interventions to prevent diarrhea, a leading killer of young children in low-income countries. Objectives: We summarize the results of blinded versus open trials of water quality interventions, describe evidence from a recent placebo-controlled trial in India suggesting that control households were put at risk from their participation, and suggest alternatives to blinded trials that could resolve continued uncertainty about the magnitude of the protective effect of water, sanitation, and hygiene (WASH) interventions without presenting ethical questions. Discussion: Concerns about reporting bias in open trial designs continue to cause uncertainty about the effectiveness of WASH interventions. However, evidence suggests that despite instructions to the contrary, placebos may encourage control group participants in blinded trials to cease practicing traditional water treatment practices in the mistaken belief that they are protected by an active intervention. Although objective outcomes such as pathogen incrimination, seroconversion, biomarkers, and anthropometry can be helpful, these are often costly, nonspecific, and unsuitable for evaluating programmatic interventions. Conclusions: Unless researchers can be assured that a placebo will not cause those in a control group to change their behavior in a manner that increases their risk, it is incumbent on researchers to use alternatives. Validated objective measures are needed for assessing the health impact of WASH interventions that are reliable, affordable, and suitable both for research and program evaluation. Citation: Clasen T, Boisson S. 2016. Assessing the health impact of water quality interventions in low-income settings: concerns associated with blinded trials and the need for objective outcomes. Environ Health Perspect 124:886–889; http://dx.doi. org/10.1289/ehp.1510532
Optimal therapy of advanced ovarian cancer: carboplatin and paclitaxel versus cisplatin and paclitaxel (GOG158) and an update on GOG0182-ICON5

Mature results from GOG158 have clearly established carboplatin and paclitaxel as an effective and well-tolerated standard regimen, providing a basis for the reference arm in GOG0182-ICON5, an ongoing multiarmed phase III trial of the Gynecologic Cancer InterGroup (GCIG) evaluating the incorporation of newer cytotoxic agents. Results from GOG158 will be reviewed, including an analysis of second-look surgical outcomes, followed by an update on the current status of GOG0182-ICON5.
Effects of the Bradyrhizobium japonicum waaL (rfaL) Gene on Hydrophobicity, Motility, Stress Tolerance, and Symbiotic Relationship with Soybeans

We cloned and sequenced the waaL (rfaL) gene from Bradyrhizobium japonicum, which infects soybean and forms nitrogen-fixing nodules on soybean roots. waaL has been extensively studied in the lipopolysaccharide (LPS) biosynthesis of enteric bacteria, but little is known about its function in (brady)rhizobial LPS architecture. To characterize its role as O-antigen ligase in the LPS biosynthesis pathway, we constructed a waaL knock-out mutant and its complemented strain named JS015 and CS015, respectively. LPS analysis showed that an LPS structure of JS015 is deficient in O-antigen as compared to that of the wild type and complemented strain CS015, suggesting that WaaL ligates the O-antigen to lipid A-core oligosaccharide to form a complete LPS. JS015 also revealed increased cell surface hydrophobicity, but it showed decreased motility in soft agar plates. In addition to the alteration in cell surface properties, disruption of the waaL gene caused increased sensitivity of JS015 to hydrogen peroxide, osmotic pressure, and novobiocin. Specifically, plant tests revealed that JS015 failed to nodulate the host plant soybean, indicating that the rhizobial waaL gene is responsible for the establishment of a symbiotic relationship between soybean and B. japonicum.
An extended spectrum of logical definitions for diagnostic sytems

The goal of this work is to develop a single uniform theory, which enables us to describe many different diagnostic systems. We will give a general definition of diagnostic systems. Our claim is that a large number of very different diagnostic systems can be described by this definition by choosing the right values for six parameters in this definition. Our work is an extension of the spectrum of logical definitions of Console and Torasso.
High gain 4 × 4 slot dipole antenna array in the 5GHz band

A novel high gain slot dipole antenna array fed by a coplanar waveguide (CPW) for 5GHz band wireless local area network (WLAN) application is proposed. Antenna element of our proposed antenna array is one sided directional slot antenna with bottom floating metal layer. This antenna array has 16 antenna elements to achieve a high gain. The RF signal is injected by CPW transmission line. The simulation and the measurement results of return losses, antenna gains and radiation patterns are presented in this paper. The bandwidth of the proposed antenna is 800MHz and the maximum peak gain is 10.7dBi at 5.85GHz.