Miracle-dz/UniFAR-FTUs huggingface dataset:
Living in a World Heritage City: stakeholders in the dialectic of the universal and particular

This article is based on research undertaken in Québec city focusing on heritage interpretation and the promotion of 'national identity'. The discussion opens with a review of the term heritage, now identified as an 'industry', but also a problematic notion located in the dialectic of the universal and the particular. An assessment of the historic quarter, a World Heritage Site, provides the basis for a critique of the differing perspectives and identities used by the various stakeholders, including local residents and visitor groups. These various perspectives, on what is a contested 'national' heritage site, are manifested in the promotion of the capital city of New France and separatist Québec and the benign but nonetheless federal presence represented by Parks Canada, the National Battlefield and National Defence Commissions, which together control and interpret the key heritage sites. In giving a voice to the local, the paper articulates the concerns of a declining but increasingly vocal resident group, reflecting the gentrification and 'touristification' of the historic district and the realities of living in aWorld Heritage City, and the conflicts between the presentation of this city to a greater francophonie, and the promotion of an urban tourism destination to a wider Canada and world.
Sentence Recast Use by Parents of Children With Typical Language and Children With Specific Language Impairment

Many early studies failed to find differences in the language input of parents to children with specific language impairments (SLI) when compared to the input provided for MLU-matched children with typical language (TL). More recent investigations have revealed significant differences in the frequency of sentence recasts provided to young children. Specifically, parents of children with SLI have been shown to produce fewer recasts than do parents of younger children with TL. Because recasts have been shown to facilitate morphosyntactic development, these findings have important assessment and treatment implications. The purpose of this study was to replicate and extend these recent findings. The sentence recast usage of the parents of 10 children with SLI was compared with the recast usage of parents of 10 younger children with TL at two points in time. This strategy enabled us to examine specific hypotheses about the quantity of recasts used by parents and the changes in patterns of use over time. The re.
High Molecular Weight Barley β-Glucan Alters Gut Microbiota Toward Reduced Cardiovascular Disease Risk

The physiological cholesterol-lowering benefits of β-glucan have been well documented, however, whether modulation of gut microbiota by β-glucan is associated with these physiological effects remains unknown. The objectives of this study were therefore to determine the impact of β-glucan on the composition of gut microbiota in mildly hypercholesterolemic individuals and to identify if the altered microbiota are associated with bioactivity of β-glucan in improving risk factors of cardiovascular disease (CVD). Using a randomized, controlled crossover study design, individuals received for 5-week either a treatment breakfast containing 3 g high molecular weight (HMW), 3 g low molecular weight (LMW), 5 g LMW barley β-glucan, or wheat and rice. The American Heart Association (AHA) diet served as the background diet for all treatment groups. Phases were separated by 4-week washout periods. Fecal samples were collected at the end of each intervention phase and subjected to Illumina sequencing of 16S rRNA genes. Results revealed that at the phylum level, supplementation of 3 g/d HMW β-glucan increased Bacteroidetes and decreased Firmicutes abundances compared to control (P < 0.001). At the genus level, consumption of 3 g/d HMW β-glucan increased Bacteroides (P < 0.003), tended to increase Prevotella (P < 0.1) but decreased Dorea (P < 0.1), whereas diets containing 5 g LMW β-glucan and 3 g LMW β-glucan failed to alter the gut microbiota composition. Bacteroides, Prevotella, and Dorea composition correlated (P < 0.05) with shifts of CVD risk factors, including body mass index, waist circumference, blood pressure, as well as triglyceride levels. Our data suggest that consumption of HMW β-glucan favorably alters the composition of gut microbiota and this altered microbiota profile associates with a reduction of CVD risk markers. Together, our study suggests that β-glucan induced shifts in gut microbiota in a MW-dependent manner and that might be one of the underlying mechanisms responsible for the physiological benefits of β-glucan.
Quantification of carotid stenosis on CT angiography.

PURPOSE Carotid artery stenosis quantification uses percent diameter ratios from conventional angiography. Multidetector high-speed CT angiography (CTA) allows direct millimeter measurement of carotid stenosis. We hypothesize a linear relationship between millimeter stenosis measurements and derived percent, alleviating cumbersome ratio calculations. METHODS Two neuroradiologists separately reviewed CTAs of 268 carotid arteries, blinded to other information. The narrowest portion of each carotid stenosis was measured in millimeters from axial source images. Distal internal carotid arteries (ICAs) were measured beyond the bulb, where walls are parallel. North American Symptomatic Carotid Endarterectomy Trial (NASCET)-style ratios were calculated for each ICA, except for suspected near-occlusions. Interobserver agreement was calculated for all measurements. Correlation coefficients were calculated comparing millimeter and derived percent stenosis, followed by regression analysis. Sensitivity and specificity values tested validity. RESULTS Interobserver agreement correlations were excellent, from 0.78 to 0.89 (2-tailed P </= .01). Excellent reader correlation permitted averaging of millimeter stenosis and distal ICA measurements, which were then used to calculate mean percent stenosis. Stenosis assessment was confidently performed from source images even with calcification. Regression analysis of mean percent as a function of mean millimeter stenosis shows a linear relationship, correlating 1.3 mm to 70% and 2.2 mm to 50% NASCET-style stenosis (Pearson's correlation of -0.95; n = 136). Direct millimeter measurement defining severe stenosis (70% or greater) has sensitivity of 88.2%, specificity of 92.4%, and negative predicted value of 98.2%. CONCLUSION There is a linear relationship between millimeter carotid stenosis diameter and derived percent stenosis. This allows prediction of NASCET-type percent from millimeter stenosis.
Adaptive Control of a Flexible Crane System With the Boundary Output Constraint

In this paper, a flexible cable with a payload attached at the bottom is considered to be the model of a crane system used for positioning the payload. The dynamics of the flexible cable coupled with the tip payload contribute to a hybrid system represented by partial-ordinary differential equations. An integral-barrier Lyapunov function (IBLF)-based control is proposed to suppress the undesirable vibrations of the flexible crane system with the boundary output constraint. Adaption laws are developed for handling parametric uncertainties. A novel IBLF is adopted to guarantee the uniform stability of the closed-loop systems without the violation of the boundary constraint. All closed-loop signals are ensured to be bounded. Extensive simulations are demonstrated to illustrate the performance of the control system.
Medición de la capacidad de carga turística de Cozumel

El estudio inicio como una iniciativa planeada de reduccion de los impactos negativos por la presencia de visitantes en un destino masivo y tambien zona protegida. Como primera parte de este proceso, la determinacion de la capacidad de carga que representa una aproximacion estimada de visitantes que un destino turistico puede aceptar sin producir danos serios al sistema ambiental. La estimacion puede ser hecha por varios metodos, pero en esta investigacion fue aplicado el metodo de Cifuentes (1999) y el analisis de indicadores claves, ademas del uso del GPS, en la isla de Cozumel, Mexico. El objetivo primario fue determinar los indicadores como estrategia para gestionar la investigacion, y como resultado, deﬁnir un valor recomendable de visitantes que el destino deberia recibir diariamente. La investigacion fue ﬁnanciada por la Universidad de Quintana Roo.
Resolution of Distance Ambiguities of Inner Galaxy Massive Star Formation Regions. II.

We report simultaneous H110α and H2CO line observations with the NRAO Green Bank Telescope toward 72 H II regions in the Spitzer Space Telescope GLIMPSE survey area (|l| = 10°-65° and |b| ≤ 1°). We used the H110α line to establish the velocity of the H II regions and H2CO absorption lines to distinguish between near and far distances. Accurate distances are crucial for the determination of physical properties of massive star formation regions. We resolved the distance ambiguity of 44 H II regions. We detected multiple H II regions along 18 lines of sight located in the longitude interval 12°-31°, primarily a result of the relatively large telescope beam width. We could not resolve distance ambiguities for lines of sight with multiple H II regions, since we could not determine which H2CO lines were being absorbed against which H II region. We examined the projected location of H II regions whose distance ambiguities have been resolved (in this work and other similar studies) in the Galactic plane and in a longitude-velocity diagram for a recognizable spiral arm pattern. Although the highest density of points in the position-position plot approximately follows the spiral arms proposed by Taylor & Cordes, the dispersion is still about as large as the separation between their proposed arms. The longitude-velocity plot shows an increase in the density of sources at the points where the spiral arm loci proposed by Taylor & Cordes are approaching the locus of tangent point velocities and a lower density between the arm loci. However, it is not possible to trace spiral arms over significant segments of Galactic longitude in the longitude-velocity plot. We conclude that a very large number of H II regions in combination with more sophisticated Galactic rotation models will be required to obtain a more continuous spiral pattern from kinematic studies of H II regions than from fully sampled surveys of H I or CO.
Um método de gestão de fornecedores baseado na avaliação da eficácia de auditorias realizadas na fase de desenvolvimento de produtos

O objetivo deste trabalho e apresentar um metodo de gestao de fornecedores baseado na avaliacao das auditorias realizadas nestes durante a fase de desenvolvimento de produtos. As auditorias sao priorizadas pelo impacto do produto fornecido ao desenvolvimento e visam identificar riscos, propor e executar planos, e analisar periodicamente o desempenho dos fornecedores para prevencao de problemas. Propoe-se que se a utilizacao das auditorias na fase de desenvolvimento for eficaz, os produtos fornecidos para o inicio da producao em serie terao maturidade e desempenho estaveis. Isso foi avaliado numa empresa do setor aeronautico e os resultados analisados em 2006 foram positivos.
User Rankings and Journalistic News Selection

User rankings provide detailed information about the news selection of internet audiences. Due to the difficult economic situation of many publishing companies, newsrooms are increasingly forced to take these data into account. This paper contributes to the debate about an increasing audience orientation in journalism. We conducted a content analysis of various media outlets and user rankings in order to explore current differences between journalistic news selection and selections of the audience. Our comparison criteria include news values and topics. The results show similarities in news values, but differences in preferred topics. Finally, we discuss the opportunities and challenges presented by user rankings for the analysis of audience behavior.
“Me in Place, and the Place in Me”

Abstract In this memoir, the central of role of food in the life of migrants is recalled in the story of an Indian family's journey to Britain in the 1950s, a time when very few South Asian restaurants or shops had been established. The memoir seeks to redress the imbalance in much writing on food and migration, where food is the primary focus, and migrants and their journeys tend to form a rather ghostly backdrop to the culinary action. The family's quest for the “food of home” highlights the centrality of culinary practices in their lives, and the relationship between food and ideas of home and belonging. It provides an alternative window into an intimate world of food and migration, offering insights into both the inner space of the migrant psyche, and outer, mobile, food geographies and social histories. Food practices are explored as a grammar for a politics of the migrant self.
Identification of a Novel DNA‐Binding Protein from Mycobacterium bovis Bacillus Calmette‐Guérin

A novel DNA‐binding protein expressed (8–10% in total protein) in Mycobacterium bovis bacillus Calmette‐Guérin was observed. This protein was designated mycobacterial DNA‐binding protein 1 (MDP1). MDP1 recognized bases, sugar moieties, phosphate‐backbone on DNA and preferentially bound to DNA guanine and cytosine. In the gel retardation assay, MDP1 preferentially bound to closed circular plasmid DNA than open circular and linear form plasmid DNA and also bound to RNA. MDP1 formed a highly polymerized structure and localized not only in the nucleoid but also at the 50S ribosomal subunits and cell surface. MDP1 was conserved in Mycobacterium thus far examined and the expression was enhanced in stationary growth phases. These results will provide a reasonable basis for further study of the function of MDP1 in living mycobacteria.
Fracture of the extensor process of the distal phalanx in a bull and a cow

Two cases of extensor process fracture of the distal phalanx in the forelimb in a Holstein bull and a lactating Holstein cow are described. Each animal showed acute onset of severe lameness with a gait characterised by lengthening of the cranial phase of the step in order to place more weight on the heel. Mild swelling and a localised pain response upon application of deep pressure above the coronet were also observed. A definitive diagnosis was made by radiography with complementary ultrasonography, which provided the best definition of the fracture fragment over the dorsal aspect of the distal interphalangeal joint. Applying a wooden block to a sound claw for three weeks was curative and provided a good prognosis in both cases.
Innovative thermal energy harvesting for zero power electronics

Thermal gradients, commonly present in our environment (fluid lines, warm fronts, electronics) are sources of energy rarely used today. This paper aims to present innovative approaches of thin and/or flexible thermal energy harvesters for smart and autonomous sensor network applications. The harvester system will be based on the collaborative work of interrelated energy nodes/units, which will be either piezo-thermofluidic converters (use of rapid thermal cycles of a working fluid) or piezo-thermomechanic converters (use of the mechanical energy developed by rapid snapping of micro-switches). The two kinds of energy nodes convert a heat flux into storable electrical energy through a piezoelectric transducer. Miniaturization of the energy nodes will lead to increased thermal transfer rates and consequently increased harvested power. To effectively use thermal energy sources in varying environments, the nodes will be adaptive versus different thermal gradients (in a predefined temperature range) and will possibly influence each other. The concept is unique in the sense that it is based on a matrix structure of micro or mini energy nodes which will work together in a collective approach to optimize the harvested energy, and which do not require the use of radiators as classical Seebeck approach, thanks to the controlled thermal resistance. This opens the door to new properties and features of the object, with better performances. It could therefore be declined on flexible substrates, allowing conformability around the sources of potential heat for low power applications.
Differences in the Gene Expression Profiles of Haemocytes from Schistosome-Susceptible and -Resistant Biomphalaria glabrata Exposed to Schistosoma mansoni Excretory-Secretory Products

During its life cycle, the helminth parasite Schistosoma mansoni uses the freshwater snail Biomphalaria glabrata as an intermediate host to reproduce asexually generating cercariae for infection of the human definitive host. Following invasion of the snail, the parasite develops from a miracidium to a mother sporocyst and releases excretory-secretory products (ESPs) that likely influence the outcome of host infection. To better understand molecular interactions between these ESPs and the host snail defence system, we determined gene expression profiles of haemocytes from S. mansoni-resistant or -susceptible strains of B. glabrata exposed in vitro to S. mansoni ESPs (20 μg/ml) for 1 h, using a 5K B. glabrata cDNA microarray. Ninety-eight genes were found differentially expressed between haemocytes from the two snail strains, 57 resistant specific and 41 susceptible specific, 60 of which had no known homologue in GenBank. Known differentially expressed resistant-snail genes included the nuclear factor kappa B subunit Relish, elongation factor 1α, 40S ribosomal protein S9, and matrilin; known susceptible-snail specific genes included cathepsins D and L, and theromacin. Comparative analysis with other gene expression studies revealed 38 of the 98 identified genes to be uniquely differentially expressed in haemocytes in the presence of ESPs, thus identifying for the first time schistosome ESPs as important molecules that influence global snail host-defence cell gene expression profiles. Such immunomodulation may benefit the schistosome, enabling its survival and successful development in the snail host.
Adults with Learning Disabilities. Theoretical and Practical Perspectives.

Gregg, Phillips, Adults with Learning Disabilities: Empowering Networks and Inclusion, Collaboration, and Self-Acceptance. Gregg, Ferri, Paradigms: A Need for Radical Reform. Hoy et al, Clinical Model Versus Discrepancy Model in Determining Eligibility for Learning Disabilities Services at a Rehabilitation Setting. Brackett, McPherson, Learning Disabilities Diagnosis in Postsecondary Students: A Comparison of Discrepancy-Based Diagnostic Models. Ross-Gordon, Sociocultural Issues Affecting the Identification and Delivery Service Models for Adults with Learning Disabilities. Riccio, Hynd, Neurobiological Research Specific to the Adult Population with Learning Disabilities. Hawks, Assessing Adults with Learning Disabilities. Hooper, Olley, Psychological Comorbidity in Adults with Learning Disabilities. Darden, Morgan, Cognitive Functioning Profiles of the Adult Population with Learning Disabilities. Hoy, Manglitz, Social and Affective Adjustment of Adults with Learning Disabilities. Wiig, Language and Communication Disorders in Adults with Learning Disabilities. Sturomski, Literacy Needs for Adults Who Have Learning Disabilities. Minskoff, Improving Employment Outcomes for Persons with Learning Disabilities. Gajar, Osgood-Smith, Service Delivery Models Effective with Adults with Learning Disabilities. Gregg, Johnson, McKinley, Learning Disabilities Policy and Legal Issues: A Consumer and Practitioner User-Friendly Guide. Gay, Facilitating Alternative Learning Techniques for Adults with Learning Disabilities through the Use of Technology.
Spindle microtubules in flux

Accurate and timely chromosome segregation is a task performed within meiotic and mitotic cells by a specialized force-generating structure – the spindle. This micromachine is constructed from numerous proteins, most notably the filamentous microtubules that form a structural framework for the spindle and also transmit forces through it. Poleward flux is an evolutionarily conserved mechanism used by spindle microtubules both to move chromosomes and to regulate spindle length. Recent studies have identified a microtubule-depolymerizing kinesin as a key force-generating component required for flux. On the basis of these findings, we propose a new model for flux powered by a microtubule-disassembly mechanism positioned at the spindle pole. In addition, we use the flux model to explain the results of spindle manipulation experiments to illustrate the importance of flux for proper chromosome positioning.
How Groups Affect Our Health and Well‐Being: The Path from Theory to Policy

Considerable evidence now exists that people can draw on social groups in order to maintain and enhance health and well-being. We review this evidence and suggest that social identity theorizing, and its development in the social identity approach to health and well-being, can help us to understand the way that groups, and the identities that underpin them, can promote a social cure. Specifically, we propose that social groups are important psychological resources that have the capacity to protect health and well-being, but that they are only utilized effectively when individuals perceive they share identity with another individual or group. However, as powerful as shared identities may be, their consequences for health are largely ignored in policy and practice. In this review, we offer a novel direction for policy, identifying ways in which building and consolidating group identification can help to capitalize effectively on the potential of group membership for health. Using this as a basis to increase awareness, we go further to offer practical interventions aimed at assessing identity resources as substantial and concrete assets, which can be cultivated and harnessed in order to realize their health-enhancing potential.
Disrupting the cortical actin cytoskeleton points to two distinct mechanisms of yeast [PSI+] prion formation

Mammalian and fungal prions arise de novo; however, the mechanism is poorly understood in molecular terms. One strong possibility is that oxidative damage to the non-prion form of a protein may be an important trigger influencing the formation of its heritable prion conformation. We have examined the oxidative stress-induced formation of the yeast [PSI+] prion, which is the altered conformation of the Sup35 translation termination factor. We used tandem affinity purification (TAP) and mass spectrometry to identify the proteins which associate with Sup35 in a tsa1 tsa2 antioxidant mutant to address the mechanism by which Sup35 forms the [PSI+] prion during oxidative stress conditions. This analysis identified several components of the cortical actin cytoskeleton including the Abp1 actin nucleation promoting factor, and we show that deletion of the ABP1 gene abrogates oxidant-induced [PSI+] prion formation. The frequency of spontaneous [PSI+] prion formation can be increased by overexpression of Sup35 since the excess Sup35 increases the probability of forming prion seeds. In contrast to oxidant-induced [PSI+] prion formation, overexpression-induced [PSI+] prion formation was only modestly affected in an abp1 mutant. Furthermore, treating yeast cells with latrunculin A to disrupt the formation of actin cables and patches abrogated oxidant-induced, but not overexpression-induced [PSI+] prion formation, suggesting a mechanistic difference in prion formation. [PIN+], the prion form of Rnq1, localizes to the IPOD (insoluble protein deposit) and is thought to influence the aggregation of other proteins. We show Sup35 becomes oxidized and aggregates during oxidative stress conditions, but does not co-localize with Rnq1 in an abp1 mutant which may account for the reduced frequency of [PSI+] prion formation.