Miracle-dz/UniFAR-FTUs huggingface dataset:
Synergistic Effects of Agronet Covers and Companion Cropping on Reducing Whitefly Infestation and Improving Yield of Open Field-Grown Tomatoes

Tomatoes (Lycopersicon esculentum Mill) are one of the biggest vegetable crops in the world, supplying a wide range of vitamins, minerals and fibre in human diets. In the tropics, tomatoes are predominantly grown under sub-optimal conditions by subsistence farmers, with exposure to biotic and abiotic stresses in the open field. Whitefly (Bemisia tabaci Gennadius) is one of the major pests of the tomato, potentially causing up to 100% yield loss. To control whitefly, most growers indiscriminately use synthetic insecticides which negatively impact the environment, humans, and other natural pest management systems, while also increasing cost of production. This study sought to investigate the effectiveness of agronet covers and companion planting with aromatic basil (Ocimum basilicum L.) as an alternative management strategy for whitefly in tomatoes and to evaluate the use of these treatments ontomato growth and yield. Two trials were conducted at the Horticulture Research and Training Field, Egerton University, Njoro, Kenya. Treatments comprised a combination of two factors, (1) growing environment (agronet and no agronet) and (2) companion planting with a row of basil surrounding tomato plants, a row of basil in between adjacent rows of tomato, no companion planting. Agronet covers and companion cropping with a row of basil planted between adjacent tomato rows significantly lowered B. tabaci infestation in tomatoes by 68.7%. Better tomato yields were also recorded in treatments where the two treatments were used in combination. Higher yield (13.75 t/ha) was obtained from tomatoes grown under agronet cover with a basil row planted in between adjacent rows of the tomato crop compared to 5.9 t/ha in the control. Non-marketable yield was also lowered to5.9 t/ha compared to 9.8 t/ha in the control following the use of the two treatments in combination. The results of this study demonstrate the potential viability of using companion cropping and agronet covers in integrated management of B. tabaci and improvement of tomato yield.
Dose-Dependent Protective Effect of Bisperoxovanadium against Acute Cerebral Ischemia in a Rat Model of Ischemia/Reperfusion Injury

PTEN (phosphatase and tensin homologue deleted on chromosome 10) is a dual-specificity lipid and protein phosphatase. The loss of PTEN was originally discovered in numerous human cancers. PTEN inhibition by bisperoxovanadium (bpV) reduces neurological damage after ischemic brain injury. The purpose of this study was to identify the optimal neuroprotective dose of bpV when administrated after focal ischemia/reperfusion (I/R) injury in rats. Focal I/R injury was induced using the middle cerebral artery occlusion method. bpV at doses of 0.25, 0.50 and 1.0 mg/kg were injected intraperitoneally just after reperfusion, with saline serving as a vehicle control. A maximal reduction in brain injury was observed with 1.0 mg/kg bpV. This dose of bpV also significantly blocked apoptosis in the penumbral cortex of rats. This beneficial effect was associated with the increasing levels of Akt phosphorylation in the penumbral cortex. These results demonstrate that the pharmacological inhibition of PTEN protects against I/R injury in a dose-dependent manner and the protective effect might be induced through upregulation of the phosphoinositide-3 kinase/Akt pro-survival pathway, suggesting a new therapeutic strategy to combat ischemic brain injury.
Correlation between MRI evidence of degenerative condylar surface changes, induction of articular disc displacement and pathological joint sounds in the temporomandibular joint.

OBJECTIVES The relationship of bony changes in the condylar surfaces in articular disc displacement without reduction in temporomandibular joint (TMJ) was investigated using diagnostic imaging. The study also evaluated whether the bony changes in the condylar surfaces limit disc and condyle motion, and produce pathological joint sounds. MATERIALS AND METHODS Thirty-seven joints in 28 patients diagnosed with degenerative bony changes in the condylar surfaces radiographically and anterior disc displacement without reduction using magnetic resonance imaging (MRI) were studied. The bony changes were assessed by radiographic examination and classified into two types: pathological bone changes (PBCs) including erosion, osteophyte formation and deformity, and adaptive bone changes (ABCs) including flattening and concavity. MRI was performed on the TMJ to examine the configuration and position of the discs. Joint sounds in the TMJ were determined using electrovibratograghy with a joint vibration analysis. RESULTS The articular disc motion to the condyle in the PBC group was smaller than in the ABC group irrespective of the configuration of the disc, even though there were no significant differences between the two types of bony changes in the disc position during jaw closing. The joint vibration analysis of the TMJ showed that joint sounds with a higher frequency were observed in the PBC group than in the ABC group. High energy levels needed to produce the higher frequencies (over 300 Hz) were observed only in the PBC group.
Assessing underlying realities of accounting's duality check by The Accounting Equation : A search for an augmented framework

This paper explores a general validity of the prevalent Accounting Equation in determining the real wealth and accountability discharge through contemporary financial reporting. In so doing, an augmented accounting framework is developed in order to indicate the gaps that may arise in the accounting equation; which is inherent in the system if compared among different layers – sign to alleged to referent (Buarillard 1983, 1994; MacIntosh 2000, Ijiri 1986, and Mattessich 2003). We argue that this augmented framework will help in enhancing our understanding, at least at the level of pedagogy and for corporate governance and discharging social responsibility, about the missing elements and the nature of financial reporting including the determination of fair values and therefore, reduce the blaming games of maintaining objectivity and neutrality about information provision for an augmented reality of wealth (economic or otherwise) for an entity.
Of Rights and Rhetoric: Discourses of Degradation and Exploitation in the Context of Sex Trafficking

International condemnations of people trafficking (particularly of women and girls for prostitution) as a human rights violation have proliferated in recent times. The deployment of human rights in this context has been supported by those who seek to challenge narrow victim hierarchies, but these accounts fail to clearly articulate which particular aspects of the activity violate which particular rights, and how. This article examines the applicability of protections against slavery and inhuman/degrading treatment, arguing that, in the context of the diversity and complexity of contemporary people trafficking, their limitations become apparent. The final part considers the concept of exploitation as an alternative basis for grounding a human rights claim. It cautions that invoking this concept without further elaboration (particularly in relation to the relevance of harm and consent) may be counter-productive, both in terms of theoretical clarity and practical implementation.
On transistor level gate sizing for increased robustness to transient faults

In this paper we present a detailed analysis on how the critical charge (Q/sub crit/) of a circuit node, usually employed to evaluate the probability of transient fault (TF) occurrence as a consequence of a particle hit, depends on transistors' sizing. We derive an analytical model allowing us to calculate a node's Q/sub crit/ given the size of the node's driving gate and fan-out gate(s), thus avoiding time costly electrical level simulations. We verified that such a model features an accuracy of the 97% with respect to electrical level simulations performed by HSPICE. Our proposed model shows that Q/sub crit/ depends much more on the strength (conductance) of the gate driving the node, than on the node total capacitance. We also evaluated the impact of increasing the conductance of the driving gate on TFs' propagation, hence on soft error susceptibility (SES). We found that such a conductance increase not only improves the TF robustness of the hardened node, but also that of the whole circuit.
A cognitive chameleon: Lessons from a novel MAPT mutation case

We report a case of frontotemporal dementia caused by a novel MAPT mutation (Q351R) with a remarkably long amnestic presentation mimicking familial Alzheimer’s disease. Longitudinal clinical, neuropsychological and imaging data provide convergent evidence for predominantly bilateral anterior medial temporal lobe involvement consistent with previously established neuroanatomical signatures of MAPT mutations. This case supports the notion that the neural network affected in MAPT mutations is determined to a large extent by the underlying molecular pathology. We discuss the diagnostic significance of anomia in the context of atypical amnesia and the impact of impaired episodic and semantic memory systems on autobiographical memory.
Effect of the span length of Granier-type thermal dissipation probes on sap flux density measurements

Abstract• Granier-type thermal dissipation sensors measure sap flux density (u) by using the temperature difference between the heater and the reference probe. To detect u correctly, heat must not be transferred to the reference probe by thermal conduction. The distance across which heat can be transferred by conduction is important for the span length of a sensor and spacing of a number of sensors. • To validate span lengths and spacing of sensors, we used numerical simulations to calculate the potential distance across which heat can be transferred by conduction. We compared measurements with an original and a modified sensor for a Japanese red pine (Pinus densiflora) from December 2004 to May 2005. The span length of the original and the modified sensor is 15 and 4 cm, respectively. • Numerical simulations showed that span length and spacing of Granier sensors should be more than 10 cm for trees in which u ceases for a few hours before the predawn period. The modified sensor underestimated u by 18–46% in winter (December–March) because its reference temperature was increased by heat transferred by conduction. The modified sensor measured u correctly in warm seasons, and only underestimated the annual amount of transpiration by 6%. Résumé• Les capteurs de dissipation thermique de type Granier mesurent la densité du flux de sève (u) en utilisant la différence de température entre le radiateur et la sonde de référence. Pour détecter u correctement, la chaleur ne doit pas être transférée à la sonde de référence par conduction thermique. La distance à travers laquelle la chaleur peut être transférée par conduction est importante pour la longueur de la portée d’un capteur et l’espacement de nombreux capteurs. • Pour valider les longueurs des portées et l’espacement des capteurs, nous avons utilisé des simulations numériques pour calculer la distance potentielle à travers laquelle la chaleur peut être transférée par conduction. Nous avons comparé les mesures faites à l’aide d’un capteur original et d’un capteur modifié pour un pin rouge du Japon (Pinus densiflora) de Décembre 2004 à Mai 2005. La longueur des portées est de 15 cm et de 4 cm respectivement pour l’original et le capteur modifié. • Des simulations numériques ont montré que la longueur de la portée et l’espacement des capteurs Granier devraient être supérieurs à 10 cm pour les arbres dans lesquels u cesse pendant quelques heures avant la période précédant l’aube. Le capteur modifié sous-estime u de 18 à 46 % en hiver (Décembre–Mars), car sa température de référence a été augmentée par la chaleur transférée par conduction. Le capteur modifié mesurée u correctement pendant les saisons chaudes, et seulement sous-estime la transpiration annuelle totale de 6 %.
Formulation and pharmacokinetic evaluation of a paclitaxel nanosuspension for intravenous delivery

Paclitaxel is a diterpenoid isolated from Taxus brevifolia. It is effective for various cancers, especially ovarian and breast cancer. Due to its aqueous insolubility, it is administered dissolved in ethanol and Cremophor® EL (BASF, Ludwigshafen, Germany), which can cause serious allergic reactions. In order to eliminate Cremophor EL, paclitaxel was formulated as a nanosuspension by high-pressure homogenization. The nanosuspension was lyophilized to obtain the dry paclitaxel nanoparticles (average size, 214.4 ± 15.03 nm), which enhanced both the physical and chemical stability of paclitaxel nanoparticles. Paclitaxel dissolution was also enhanced by the nanosuspension. Differential scanning calorimetry showed that the crystallinity of paclitaxel was preserved during the high-pressure homogenization process. The pharmacokinetics and tissue distribution of paclitaxel were compared after intravenous administration of paclitaxel nanosuspension and paclitaxel injection. In rat plasma, paclitaxel nanosuspension exhibited a significantly (P < 0.01) reduced area under the concentration curve (AUC)0–∞ (20.343 ± 9.119 μg · h · mL−1 vs 5.196 ± 1.426 μg · h · mL−1), greater clearance (2.050 ± 0.616 L · kg−1 · h−1 vs 0.556 ± 0.190 L · kg−1 · h−1), and shorter elimination half-life (5.646 ± 2.941 vs 3.774 ± 1.352 hours) compared with the paclitaxel solution. In contrast, the paclitaxel nanosuspension resulted in a significantly greater AUC0–∞ in liver, lung, and spleen (all P < 0.01), but not in heart or kidney.
Drug safety evaluation of maraviroc for the treatment of HIV infection

Introduction: Maraviroc is the only C-chemokine receptor 5 (CCR5) antagonist approved for the treatment of infection with HIV. This article reviews the safety and efficacy of maraviroc in the treatment of HIV infection. Areas covered: The PubMed database was searched using the keywords ‘maraviroc’ and ‘HIV’. In addition, conference proceedings from CROI, IAS and EACS meetings were searched for maraviroc clinical trials. The PubMed search revealed one Phase IIb – III clinical trial in treatment-naive HIV+ patients (MERIT) and three Phase IIb – III randomized clinical trials (RCTs) in treatment-experienced patients (MOTIVATE 1 and 2, A4001029). All RCTs showed an excellent safety profile for maraviroc in the treatment of HIV-1 infection. However, long-term (> 3 years) safety data generated on maraviroc therapy are still scarce. Based on the findings from RCTs so far, no relevant toxicities and co-morbidities such as coronary heart disease or hepatotoxicity have been described. The overall CD4+ cell count increase resulting from a maraviroc-containing regimen appears to be higher than those seen with other antiretroviral regimens. However, the significance remains controversial. To date, maraviroc has shown a potent and durable virological efficacy profile for the treatment of HIV-1 infection. The only use of maraviroc depends on pretreatment testing for CCR5 tropism. Expert opinion: Maraviroc is a generally safe and well-tolerated medication for the treatment of HIV-1 infection with a unique mechanism of action. Long-term (i.e., > 5 years) risks are not known and have to be carefully monitored.
Uncemented total hip arthroplasty in osteoarthritis of hip secondary to low and high dislocated hips: A mid-term follow-up study

Background: Performing successful total hip replacement (THR) in dysplastic, subluxed, and dislocated hip is a challenging task. Here, we assessed midterm clinical and radiological outcomes of uncemented total hip arthroplasty in osteoarthritis (OA) of hip secondary to Hartofilakidis low and high-dislocated hips with a mean follow-up of 8.8 years. Materials and Methods: A retrospective study of prospectively collected data was designed involving all consecutive patients who underwent uncemented THR for OA of hip secondary to developmental dysplasia of the hip and Grade II or Grade III Hartofilakidis classification. Results: Thirty-two patients underwent 45 THR, with 23 Grade II (low dislocation) and 22 Grade III (high-dislocation) of Hartofilakidis classification. Thirteen patients had bilateral hip replacements, 19 patients had unilateral THR. There was highly statistically significant difference between preoperative and postoperative HHS and SF-36v2™ at each follow-up. Survivorship of original implant was 98.88% at a mean follow-up of 8.8 years. The mean improvement in leg length in this series was 3.6 cm (1.8-4.5, 95% confidence interval). No sciatic nerve or femoral nerve palsies were observed. Conclusions: Uncemented THR provides better function and quality of life. However, longer follow-up studies are needed to assess survivorship of uncemented THR in Hartofilakidis low and high-dislocations.
Pik3ip1 Modulates Cardiac Hypertrophy by Inhibiting PI3K Pathway

Cardiac hypertrophy is an adaptive response to various physiological and pathological stimuli. Phosphoinositide-3 kinase (PI3K) is a highly conserved lipid kinase involved in physiological cardiac hypertrophy (PHH). PI3K interacting protein1 (Pik3ip1) shares homology with the p85 regulatory subunit of PI3K and is known to interact with the p110 catalytic subunit of PI3K, leading to attenuation of PI3K activity in liver and immune cells. However, the role of Pik3ip1 in the heart remains unknown. In the present study, the effects of Pik3ip1 on cardiac hypertrophy were examined. We found that the expression level of Pik3ip1 was markedly higher in cardiomyocytes than in fibroblasts. The interaction of Pik3ip1 with the p110a subunit of PI3K in the heart was identified by immunoprecipitation using neonatal rat cardiomyocytes (NRCM). Approximately 35% knockdown of Pik3ip1 was sufficient to induce myocardial hypertrophy. Pik3ip1 deficiency was shown to lead to activation of PI3K/protein kinase B (AKT)/ mammalian target of rapamycin (mTOR) signaling pathway, increasing protein synthesis and cell size. However, adenovirus-mediated overexpression of Pik3ip1 attenuated PI3K-mediated cardiac hypertrophy. Pik3ip1 was upregulated by PHH due to swimming training, but not by pathological cardiac hypertrophy (PAH) due to pressure-overload, suggesting that Pik3ip1 plays a compensatory negative role for PHH. Collectively, our results elucidate the mechanisms for the roles of Pik3ip1 in PI3K/AKT signaling pathway.
Solidarity and Distinction in Blood: Contamination, Morality and Variability

This is an ethnographic exploration into the meanings of contaminated blood. Intense commercial harvesting of human plasma, a blood component, in rural central China during the 1990s resulted in extensive HIV infection among donors. The lack of viral diversity among these infected donors, as revealed by research in molecular epidemiology, confirms that this epidemic took hold and spread rapidly with deadly efficiency through unsanitary plasmapheresis. The distinction in viral strains between this epidemic and the spread of HIV via other routes of transmission in other parts of China serves also to promote claims to victimhood by infected rural commercial donors in the ambiguous geography of moral ambivalence towards carriers of the virus. Through a series of vignettes from field research among rural plasma donors in China, this article examines the tensions between solidarity and distinction, victimhood and responsibility, alliance and strife as they play out in meanings derived from contaminated blood, within their everyday experience and also within their participation in the broader HIV/AIDS activism, in which their distinction is inevitably challenged.
High efficiency MOS-FET rectifier device

Two new Vertical DSA MOS-FETs were designed and tested. These devices both have a 13 milli-ohm RON and has a low transient loss, and a 2,300pF, a 2,i00pF Ciss, respectively. From circuit experiments, about 20% improvement is confirmed in the loss ratio.
Young Children’s Intonational Marking of New, Given and Contrastive Referents

In the current study we investigate whether 2- and 3-year-old German children use intonation productively to mark the informational status of referents. Using a story-telling task, we compared children’s and adults’ intonational realization via pitch accent (H*, L* and de-accentuation) of New, Given, and Contrastive referents. Both children and adults distinguished these elements with different pitch accents. Adults, however, de-accented Given information much more often than the children, especially the younger children. Since a failure to de-accent Given information may be a characteristic of caregiver speech, in a second study we tested how caregivers talking to their young children realize Given and New referents. In this discourse situation, the caregivers quite often failed to de-accent Given information, raising the possibility that the younger children were simply reproducing the pitch accents they had heard adults using.
Knot Selection for Least Squares Thin Plate Splines

An algorithm for the selection of knot point locations for approximation of functions from large sets of scattered data by least squares thin plate splines is given. The algorithm is based on the idea that each data point is equally important in defining the surface, which allows the knot selection process to be decoupled from the least squares. Properties of the algorithm are investigated, and examples demonstrating it are given. Results of some least squares approximations are given and compared with other approximation methods.
Women Learning in Garment Work: Solidarity and Sociality

This article explores processes and possibilities for critical learning in the workplace, with a focus on workers laboring in what are often exploitive and dehumanizing conditions. The argument is based on a study of work-life learning of women, mostly new immigrants, employed long-term at an Alberta garment manufacturing plant. It is argued that their negotiations of work conditions are nested in various areas of learning associated with everyday practices, small communities, labor organizing processes, and English learning classes. These are argued to have generated solidarity through learning about sociality, resistance, and personal worth. These solidarities appear to be configured by energies of both transformation and reproduction that are threaded together and generated simultaneously as women learned to survive within the system while supporting one another in a vital interdependent social network. The discussion explores how these dynamics unfolded, and their effects on how different women positioned themselves and their knowledge.