Miracle-dz/UniFAR-FTUs huggingface dataset:
The legal labour market and the training needs of women returners in the UnitedKingdom

Abstract This article examines a particular instance of the relationship between gender, training provision and the labour market, namely the provision of training for women solicitors wishing to return to the labour market after a career break. The specific empirical material, which is gathered from a sample of women solicitors, both returners and non-returners, in West and North Yorkshire, is explored in the context of demand-side and supply-side explanations of women's position in the labour market. However, we also argue for a perspective which takes account of the culture of the profession and which undermines the assumption of economic rationality underpinning many labour market studies. Similarly, our exploration of the potential of training for easing labour-market re-entry is evaluated within the context of the gendered ethos of the solicitor's profession, as is the discussion of the curriculum design issues in professional women returners' training which arise out of the research.
Residential Mobility in Dutch Housing Markets

A one percent stratified random sample of all Dutch households (comprising 62 000 households) is used to examine mobility in the Dutch housing market. Two techniques, proportional reduction in uncertainty (PRU), and logit analysis are used to evaluate the relative contribution of independent variables in explaining mobility across the tenure types and by housing market regions. The PRU technique is used to select the best variables and to simplify the categories of those variables before logit analyses. Given a reduced set of variables and combinations of categories, logit models are utilized to provide parameter estimates of the contributions of the independent variables. The PRU technique shows that it is possible to make considerable simplifications in the combinations of categories for variables, and the logit models (for owners, public renters, and private renters) indicate distinct differences in the combinations of variables which are most appropriate in each of these sectors. In particular, the logit analysis shows that the relationship between age and mobility is almost linear, but between income and mobility it is curvilinear, and that evaluating interaction effects adds significantly to our understanding of the reason to move or to stay. The models show that it is necessary to treat the three tenure sectors separately, even though age, just as we expected, dominates all sectors in terms of its explanatory power. Although there are not large regional effects, the models change for different regions of the country.
An integrated data mining framework for analysis and prediction of battery characteristics

Batteries play an important role in modern sustainable energy systems. However, batteries are expensive and have a limited life time. Having a deep understanding of how batteries operate in working situations is crucial to designing advanced control mechanisms. Battery performance and life time is highly dependent on how it is used and also on environmental working conditions. While batteries have been extensively studied through model-based approaches, there is no previous work about modeUng behavior based on data analytic methods. In this paper, we propose an integrated data-driven framework to study the behavior of battery systems in a grid, based on data mining techniques. The proposed method provides a high level characterization of battery behavior and online parameter estimation using supervised and unsupervised learning methods. This work can be used in intelligent control systems and would help administrators to know what is happening inside a battery.
P-toS and StoP imaging of a sharp lithosphere-asthenosphere boundary beneath eastern North America

[1] S-to-P (Sp) scattered energy independently confirms the existence of a seismic velocity discontinuity at the lithosphere-asthenosphere boundary that was previously imaged using P-to-S (Ps) scattered energy in eastern North America. Exploration of the different sensitivities of Ps and Sp scattered energy suggests that the phases contain independent yet complementary high-resolution information regarding velocity contrasts. Combined inversions of Ps and Sp energy have the potential to tightly constrain associated velocity gradients. In eastern North America, inversions of Sp and Ps data require a strong, 5–10% velocity contrast that is also sharp, occurring over less than 11 km at 87–105 km depth. Thermal gradients alone are insufficient to create such a sharp boundary, and therefore another mechanism is required. A boundary in composition, hydration, or a change in anisotropic signature could easily produce a sufficiently localized velocity gradient. Taken separately, the magnitudes of the effects of these mechanisms are too small to match our observed velocity gradients. However, our observations may be explained by a boundary in hydration coupled with a boundary in depletion and/or anisotropy. Alternatively, a small amount of melt in the asthenosphere could explain the velocity gradient. The tight constraints on velocity gradients achieved by combined modeling of Ps and Sp energy offer promise for defining the character of the lithosphere-asthenosphere boundary globally.
The impact of interoperability of electronic health records on ambulatory physician practices: a discrete-event simulation study.

BACKGROUND The effect of health information technology (HIT) on efficiency and workload among clinical and nonclinical staff has been debated, with conflicting evidence about whether electronic health records (EHRs) increase or decrease effort. None of this paper to date, however, examines the effect of interoperability quantitatively using discrete event simulation techniques. OBJECTIVE To estimate the impact of EHR systems with various levels of interoperability on day-to-day tasks and operations of ambulatory physician offices. METHODS Interviews and observations were used to collect workflow data from 12 adult primary and specialty practices. A discrete event simulation model was constructed to represent patient flows and clinical and administrative tasks of physicians and staff members. RESULTS High levels of EHR interoperability were associated with reduced time spent by providers on four tasks: preparing lab reports, requesting lab orders, prescribing medications, and writing referrals. The implementation of an EHR was associated with less time spent by administrators but more time spent by physicians, compared with time spent at paper-based practices. In addition, the presence of EHRs and of interoperability did not significantly affect the time usage of registered nurses or the total visit time and waiting time of patients. CONCLUSION This paper suggests that the impact of using HIT on clinical and nonclinical staff work efficiency varies, however, overall it appears to improve time efficiency more for administrators than for physicians and nurses.
How has microcredit supported agriculture? Evidence using panel data from Bangladesh

Improving agricultural productivity has received a greater attention in recent years amid concerns about rising food insecurity, population pressures, and climate change. Many believe that better access to institutional credit, spanning microcredit as well as commercial and agricultural banks, can help rural households smooth risks, and access inputs and other technology to modernize agriculture and improve farm/nonfarm linkages. We use recently augmented household panel data spanning over 20 years in Bangladesh to examine the effects of rural credit expansion (both microcredit and formal bank channels) on outcomes for agricultural households. We find that microcredit has benefited households with lower landownings, raising agricultural income from activities such as livestock rearing that require less land, as well as nonfarm income diversification for all households, but with the strongest effect for landless or near-landless households. We do not find effects of microcredit on crop income, but do, however, find that reported supply-side credit constraints significantly lower crop income. Borrowing by both men and women has contributed to nonfarm income growth for marginal farmers, but only men's borrowing has contributed to nonfarm income growth among higher landowning groups.
Is Patience a Virtue? The Unsentimental Case for the Long View in Evaluating Returns

In this article, Donoho, Crenian, and Scanlan report the results of their study into the cost of institutional investor impatience. Using Monte Carlo simulation techniques, the authors construct an idealized world with a universe of investment managers of precisely quantified skill, with skill levels varying among the managers. Although many institutions base manager hiring decisions heavily on the manager’s performance in the most recent months or years, the authors’ simulations show that institutions that rely on longer performance horizons of 5–10 years are more likely to find and stick with the better managers. This happens because on shorter time scales, the relatively few highly skilled managers are often temporarily outperformed by one of the many lesser-skilled managers, specifically, unskilled managers who have recently happened to simply be lucky. Hence, if a plan that previously was long-term oriented starts to hire managers based on short-term results, it will often find that the newly chosen manager underperforms both his own previous performance and also the manager previously managing the plan’s funds. It can, however, truly take patience to keep a skilled manager in a fund portfolio. In the authors’ simulations, skilled managers have deeper, longer, and more frequent drawdowns than many investors would expect.
Modifications to swede (Brassica napus L.) anterior to the terminal ileum of pigs: some implications for the analysis of dietary fibre

1. The degradation of a swede (Brussica nupus L., cv. Danestone) diet anterior to the terminal ileum was studied in two pigs fitted with T-shaped cannulas 150 mm before the ileo-caecal junction. Digestibility was calculated with reference to chromic oxide and polyethylene glycol. 2. In addition to the total loss of free glucose and fructose, there were substantial modifications to cell-wall material recovered in digesta. These included the apparent loss of 46–50% of uronic acid residues, 72–78% of phenolic material and 10–24% of cellulose initially present in the feed, and a partial solubilization of some hemicellulose components. 3. Since ‘fibre’ recovered at the terminal ileum differed in a number of important respects from ingested fibre, a number of methods for the analysis of dietary fibre were examined to establish (1) the extent to which analysis of feed represented material recovered at the terminal ileum and (2) whether such methods could be applied directly to digesta samples. Results were compared with a complete analysis of water-soluble (620 g/kg dry matter) and water-insoluble (380 g/kg dry matter) fractions of feed. 4. Chemical fractionation techniques gave more reliable quantitative estimates of fibre than in vitro enzymic digestion methods which overestimated fibre. Acid- and neutral-detergent methods both gave too low an estimate of fibre. As none of the methods could allow for the loss of components (particularly pectic polysaccharides) found by sampling at the terminal ileum, none gave an accurate qualitative or quantitative representation of fibre at this point in the gut. 5. It is suggested that, as vegetable fibre recovered at the terminal ileum has already undergone partial hydrolysis, a more dynamic model of dietary fibre, in which the action of gut micro-organisms is considered, may be required to establish possible physiological roles of fibre or fibre components in the digestive tract. Recovery of digesta from sites of interest may be the only way of reliably estimating fibre or specific fibre components at different levels of the gut. This approach to dietary fibre may be impractical when applied directly to humans but the digestive tract of the pig may be a suitable alternative model.
Does the Presence of Venture Capitalists Improve the Survival Profile of IPO Firms

The role of venture capital in the creation of the public corporation is now widely recognized. This study investigates whether venture capitalists add value to the going public process by improving the survival profile of IPO issuers. The survival of IPO issuers is not only likely to depend on managerial actions but also on the effectiveness of key market participants such as investment bankers and analysts. The form and function of the venture capital industry allows venture capitalists to influence the actions of managers, investment bankers, and analysts, and attract institutional interest. Conducting survival analyses using the Cox hazard methodology, we find that the involvement of venture capitalists improves the survival profile of IPO firms. Several other variables that are potentially influenced by VC involvement like R&D allocations, analyst following, investment banker prestige, and success on road shows are also positively related to the survival time of IPO issuers. Copyright Blackwell Publishers Ltd 2000.
Autophagy in blood cancers: biological role and therapeutic implications

Autophagy is a cell recycling process the molecular apparatus of which has been identified over the past decade. Autophagy allows cells to survive starvation and inhospitable conditions and plays a key role in numerous physiological functions, including hematopoiesis and immune responses. In hematologic malignancies, autophagy can either act as a chemo-resistance mechanism or have tumor suppressive functions, depending on the context. In addition, autophagy is involved in other important aspects of blood cancers as it promotes immune competence and anti-cancer immunity, and may even help enhance patient tolerance to standard treatments. Approaches exploiting autophagy, either to activate or inhibit it, could find broad application in hematologic malignancies and contribute to improved clinical outcomes. These aspects are discussed here together with a brief introduction to the molecular machinery of autophagy and to its role in blood cell physiology.
Association between MMP-3 polymorphisms among Chinese patients with osteonecrosis of the femoral head

Many potential causative factors are related to the initiation and progression of osteonecrosis of the femoral head (ONFH). The matrix metalloproteinase/tissue inhibitor of metalloproteinases (MMPs/TIMPs) system was found to play a significant role in the development of ONFH. The aim of this study is to investigate the association between polymorphisms of MMP-3 and ONFH in the Chinese population. We selected 8 single-nucleotide polymorphisms (SNPs) in 2 genes selected from the MMPs/TIMPs system in a case–control study with 585 cases of ONFH and 507 healthy controls. Odds ratios (ORs) and 95% confidence intervals (CIs) were estimated using the chi-squared test, genetic model analysis, haplotype analysis, and stratification analysis. We found that the minor allele of rs650108 and rs522616 (p<0.05) was assumed a risk allele compared to the wild-type allele. In the genetic model analysis, We observed two susceptibility SNPs additionally: rs650108, dominant model analyses (with adjustment: OR=0.73; 95%CI 0.56-0.95; p=0.017) and additive model analyses (with adjustment: OR=0.83; 95%CI 0.70-0.99; p=0.044); and rs522616 recessive model analyses (with adjustment: OR=1.52; 95%CI 1.07-2.14; p=0.018) and additive model analyses (with adjustment: OR=1.21; 95% CI 1.02-1.44; p=0.033). Our results verify that genetic variants of MMP3 contribute to ONFH susceptibility in the population of northern China. In addition, we found that gender differences might interact with MMP3 polymorphisms to contribute to the overall susceptibility to ONFH.
Changes in Mint1, a Novel Synaptic Protein, After Transient Global Ischemia in Mouse Hippocampus

Mints (munc18-interacting proteins) are novel multimodular adapter proteins in membrane transport and organization. Mint1, a neuronal isoform, is involved in synaptic vesicle exocytosis. Its potential effects on development of ischemic damage to neurons have not yet been evaluated. The authors examined changes in mint1 and other synaptic proteins by immunohistochemistry after transient global ischemia in mouse hippocampus. In sham-ischemic mice, immunoreactivity for mint1 was rich in fibers projecting from the entorhinal cortex to the hippocampus and in the mossy fibers linking the granule cells of the dentate gyrus to CA3 pyramidal neurons. Munc18-1, a binding partner of mint1, was distributed uniformly throughout the hippocampus, and synaptophysin 2, a synaptic vesicle protein, was localized mainly in mossy fibers. After transient global ischemia, mint1 immunoreactivity in mossy fibers was dramatically decreased at 1 day of reperfusion but actually showed enhancement at 3 days. However, munc18-1 and synaptophysin 2 were substantially expressed in the same region throughout the reperfusion period. These findings suggest that mint1 participates in neuronal transmission along the excitatory pathway linking the entorhinal cortex to CA3 in the hippocampus. Because mint1 was transiently decreased in the mossy fiber projection after ischemia, functional impairment of neuronal transmission in the projection from the dentate gyrus to CA3 pyramidal neurons might be involved in delayed neuronal death.
The Effects of International Joint Ventures on Shareholder Wealth

The purposes of this study are to measure the wealth effects of international joint ventures on the U.S. firms' shareholders and to determine whether these effects are related to the economic status of the partner's home country. The results indicate that overall investor reactions to joint ventures with foreign firms are negative and that only joint ventures with firms from lesser developed countries have nonnegative effects on shareholders' wealth. These findings are in contrast with previous reports of positive stock price reactions to both domestic and international joint ventures. Copyright 1990 by MIT Press.
Does message framing affect changes in behavioural intentions in people with psoriasis? A randomized exploratory study examining health risk communication

Abstract Message framing is important in health communication research to encourage behaviour change. Psoriasis, a long-term inflammatory skin condition, has additional comorbidities including high levels of anxiety and cardiovascular disease (CVD), making message framing particularly important. This experimental study aimed to: (1) identify whether health messages about psoriasis presented as either gain- or loss-framed were more effective for prompting changes in behavioural intentions (BI), (2) examine whether BI were driven by a desire to improve psoriasis or reduce CVD risk; (3) examine emotional reactions to message frame; and (4) examine predictors of BI. A two by two experiment examined the effects on BI of message frame (loss vs. gain) and message focus (psoriasis symptom reduction vs. CVD risk reduction). Participants with psoriasis (n = 217) were randomly allocated to one of four evidence-based health messages related to either smoking, alcohol, diet or physical activity, using an online questionnaire. BI was the primary outcome. Analysis of variance tests and hierarchical multiple regression analyses were conducted. A significant frame by focus interaction was found for BI to reduce alcohol intake (p = .023); loss-framed messages were more effective for CVD risk reduction information, whilst gain-framed messages were more effective for psoriasis symptom reduction information. Message framing effects were not found for BI for increased physical activity and improving diet. High CVD risk was a significant predictor of increased BI for both alcohol reduction (β = .290, p < .01) and increased physical activity (β = −.231, p < .001). Message framing may be an important factor to consider depending on the health benefit emphasised (disease symptom reduction or CVD risk reduction) and patient-stated priorities. Condition-specific health messages in psoriasis populations may increase the likelihood of message effectiveness for alcohol reduction.
ECOLOGICAL AND REPRODUCTIVE CHARACTER DISPLACEMENT OF AN ENVIRONMENTAL GRADIENT

Abstract Character displacement, in which coevolution of similar species alters their phenotypes, can be difficult to identify on the basis of observational data alone. In two‐species systems, the most commonly identified (i.e., classic) resulting pattern is greater phenotypic difference between species in sympatry than allopatry. We show that restricting studies to this pattern may exclude many instances of character displacement, particularly in the presence of spatial environmental gradients. We present four spatial models of character displacement in quantitative traits affecting competition and hybridization between the species. Our models highlight the connections between range limits and character displacement in continuous space. We conclude that the classic pattern is less likely to occur for a trait affecting resource acquisition than for a trait affecting mate choice. We also show that interspecific hybridization (when hybrids are inviable), even in very small amounts, has marked effects on the shape and stability of borders between species and the nature of character displacement. A survey of the empirical literature shows that character displacement studies often lack analysis of spatial phenotype and abundance data. We recommend more careful spatial sampling in character displacement studies, and we illustrate how comparison of clines in mean phenotype in sympatry and allopatry can be used to suggest the action of character displacement.
Resistance of Marine Bacterioneuston to Solar Radiation

ABSTRACT A total of 90 bacterial strains were isolated from the sea surface microlayer (i.e., bacterioneuston) and underlying waters (i.e., bacterioplankton) from two sites of the northwestern Mediterranean Sea. The strains were identified by sequence analysis, and growth recovery was investigated after exposure to simulated solar radiation. Bacterioneuston and bacterioplankton isolates were subjected to six different exposure times, ranging from 0.5 to 7 h of simulated noontime solar radiation. Following exposure, the growth of each isolate was monitored, and different classes of resistance were determined according to the growth pattern. Large interspecific differences among the 90 marine isolates were observed. Medium and highly resistant strains accounted for 41% and 22% of the isolates, respectively, and only 16% were sensitive strains. Resistance to solar radiation was equally distributed within the bacterioneuston and bacterioplankton. Relative contributions to the highly resistant class were 43% for γ-proteobacteria and 14% and 8% for α-proteobacteria and the Cytophaga/Flavobacterium/Bacteroides (CFB) group, respectively. Within the γ-proteobacteria, the Pseudoalteromonas and Alteromonas genera appeared to be highly resistant to solar radiation. The majority of the CFB group (76%) had medium resistance. Our study further provides evidence that pigmented bacteria are not more resistant to solar radiation than nonpigmented bacteria.