Miracle-dz/UniFAR-FTUs huggingface dataset:
THERE IS MORE TO POLLINATOR‐MEDIATED SELECTION THAN POLLEN LIMITATION

Spatial variation in pollinator‐mediated selection (Δβpoll) is a major driver of floral diversification, but we lack a quantitative understanding of its link to pollen limitation (PL) and net selection on floral traits. For 2–5 years, we quantified Δβpoll on floral traits in two populations each of two orchid species differing in PL. In both species, spatiotemporal variation in Δβpoll explained much of the variation in net selection. Selection was consistently stronger and the proportion that was pollinator‐mediated was higher in the severely pollen‐limited deceptive species than in the rewarding species. Within species, variation in PL could not explain variation in Δβpoll for any trait, indicating that factors influencing the functional relationship between trait variation and pollination success govern a major part of the observed variation in Δβpoll. Separating the effects of variation in mean interaction intensity and in the functional significance of traits will be necessary to understand spatiotemporal variation in selection exerted by the biotic environment.
Underlying Agreements Between Quantitative and Qualitative Research

A review of the methodological literature describing mixed-methods and quantitative and qualitative research paradigms suggest that though many have rejected the so-called paradigm wars there remains much focus on what is different about each research tradition. This has borne out in practice where professional organizations often have subgroups dedicated to the study of one tradition or another. Indeed, Human Resources Development Review has issued calls for manuscripts that explore this topic. This article examines the idea that there can be times when it is best to think of research as a monolithic paradigm rather than a distinct set of subparadigms. The reason for this is there are a number of common research scenarios where it is best to apply perspectives that might typically be characterized as qualitative as well as ones that are considered to be qualitative in orientation (e.g., using contextual information to make judgments about practical significance). There are other scenarios where the underlying goal of a procedure from, say the quantitative paradigm is similar to that from the qualitative realm (e.g., exploratory factor analyses and thematic analyses). There are of course real differences among the paradigms, but overemphasis on division might obfuscate how to conduct rigorous research. The article closes by encouraging readers to let their research questions dictate methodological approach, in the context of the purpose, rather than building questions around techniques that tend to align with different subparadigms.
“Confortation”: about a new qualitative category for analyzing biomedical texts

In this paper we present a new approach to the expression of certainty and uncertainty in scientific experimental articles. This will permit to ascertain the validity of knowledge extracted from biological literature and used to automatically populate a domain ontology. We argue that lexical terms such as show, find, observe. express a semantic category different from the one characterized by markers such as demonstrate, validate, support. We name the latter category “confortation” as it conveys a notion of strengthening and we propose five other semantic categories: lack of knowledge, objects of study, hypothesis, observations, and general knowledge. This last category and the linguistic phenomenon of reported speech are respectively examined as consensual truth and as knowledge reported from identified scientific sources.
Mechanism for the Decrease in the FIP1L1-PDGFRα Protein Level in EoL-1 Cells by Histone Deacetylase Inhibitors

Background: Acetylation and deacetylation of proteins occur in cells in response to various stimuli, and are reversibly catalyzed by histone acetyltransferase and histone deacetylase (HDAC), respectively. EoL-1 cells have an FIP1L1-PDGFRA fusion gene that causes transformation of eosinophilic precursor cells into leukemia cells. The HDAC inhibitors apicidin and n-butyrate suppress the proliferation of EoL-1 cells and induce differentiation into eosinophils by a decrease in the protein level of FIP1L1-PDGFRα without affecting the mRNA level for FIP1L1-PDGFRA. In this study, we analyzed the mechanism by which the protein level of FIP1L1-PDGFRα is decreased by apicidin and n-butyrate. Methods: EoL-1 cells were incubated in the presence of the HDAC inhibitors apicidin, trichostatin A or n-butyrate. The protein levels of FIP1L1-PDGFRα and phosphorylated eIF-2α were determined by Western blotting. Actinomycin D and cycloheximide were used to block RNA synthesis and protein synthesis, respectively, in the chasing experiment of the amount of FIP1L1-PDGFRα protein. Results: When apicidin- and n-butyrate-treated EoL-1 cells were incubated in the presence of actinomycin D, the decrease in the protein level of FIP1L1-PDGFRα was significantly enhanced when compared with controls. In contrast, the protein levels were not changed by cycloheximide among these groups. Apicidin and n-butyrate induced the continuous phosphorylation of eIF-2α for up to 8 days. Conclusions: The decrease in the level of FIP1L1-PDGFRα protein by continuous inhibition of HDAC may be due to the decrease in the translation rate of FIP1L1-PDGFRA.
Placing “Diverse Voices” at the Center of Teacher Education A Pre-Service Teacher's Conception of Educacion and Appeal to Caring

W i t h the context of teacher education, Carlos is unique. ' As a young, bilingual me xi can^"^ who was born in Chicago but grew up in Dallas, he does not fit the profile of the typical graduate of a teacher education program: "white, female, 21 years old, speaks only English, [and] from a small town" (National Association of State Boards of Education 14). On the other hand, he seems representative of a group Joseph and Burnaford characterize as "empowered professionals," teachers who believe they can make changes happen (18-19). Throughout the classroom observations I conducted during a six-week summer arts p r ~ g r a m , ~ I make references to the fact that he appears at the classroom door fully prepared, calm, and, most importantly, concerned with his students' general well-being. Describing the challenges of recruiting culturally diverse teachers, Dillard advocates, "There is a critical need for teacher education reform that is informed by diverse voices" ("Placing" 85). Yet, Guyton and colleagues assert that the work of teachers of color and of males teaching in elementary schools remains largely uninvestigated (643-644). The limited attention may stem from the fact that teachers of color represent 12-14% of the U.S. teacher workforce (Grant and Secada 404), while male elementary teachers account for fewer than 15% (Brookhart and Loadman 197). In this study, I focus on car lo^,^ a pre-service, drama teacher who expressed comfort with learning about students' cultures and experiential backgrounds. He also frequently used the phrase, "caring for the student," in reference to how he recognized a need for a particular classroom action. This investigation originated from reading an article written by Dillard who asked, "What does the teacher of color bring to the teaching and learning setting which is . inherently of value in our increasingly diverse schools? " (6). Because Carlos self-identifies as apersona Mexicana and a teacher of color, I took that same question to his classroom of culturally diverse students. My purpose was to shed light on his struggles and successes as he dealt with the ethic of care and the reality of cultural diversity. The study provided an account of the conclusions he reached about what constitutes a drama teaching. The account was grounded in his language, definitions, and experiences. At this point, there are obvious cautions that I want to acknowledge. First, it is difficult to equate teaching in a summer drama program with teaching elementary school throughout the academic year. Also, ths study does not seek to
Differences Between Adopted and Nonadopted Adolescents in Wilderness and Residential Treatment

Adopted children are disproportionately represented in residential treatment programs in the United States. Adopted children in the United States constitute only 2% to 3% of the U.S population. Nevertheless, they comprise approximately 16.5% of the population in residential care. This descriptive study evaluated a sample of 473 psychological evaluations of adolescents in wilderness and residential treatment centers. Results indicated that, compared with nonadopted youth, adopted youth had greater histories of recent trauma, higher rates of suicidal tendency and biological parents’ mental illness, and poorer academic achievement. However, there were no significant differences between adopted and nonadopted youths in terms of defiant behaviors, IQ, substance use/abuse, reasons for referral, impulsivity, anxiety, or depression. Study results suggest that wilderness and residential programs may need to target programmatic elements specifically to meet the special needs of adopted adolescents who comprise a significant percentage of their client population.
A Profile of Elementary School Teachers Involved in a Professional Development School

Abstract This exploratory study identifies the characteristics of elementary school teachers who were involved in professional development school (PDS) activities at one PDS site. It describes 42 teachers' level of involvement in the PDS partnership using both a subjective (respondents' self-report) and an objective (university team's assessment, based on the number and types of PDS activities in which teachers had engaged) measure of involvement. Using survey data collected at the end of the second year of the PDS's implementation, the researchers calculated univariate descriptive statistics, cross-tabulations, and correlation coefficients to profile who participated in the PDS and the extent to which they did so. They found that, on both measures of level of involvement, most of the teachers were somewhat or highly involved in PDS activities. While the two indicators are moderately, positively, and significantly related to each other, they yielded different results when they were analyzed in relation to four other sets of variables. The findings point to the need to explore more fully the characteristics of those teachers who do participate in PDS partnerships in order to develop more effective strategies to involve teachers in such collaborative arrangements and to achieve PDS purposes.
What should psychiatric trainees in years 1–3 gain from CBT training? Implications from a Royal College Divisional Workshop

Abstract Competencies for psychiatric training have been developed that reflect what psychiatrists have to be able to do in order to function in their role. Although the need for a formally delivered psychotherapy experience is assumed and associated competencies are represented in the curriculum, it is not clear which competencies thereby achieved can be translated into generic practice. This paper reports the outcomes of a workshop held at an academic regional meeting of the Royal College of Psychiatrists. Potential competencies to be achieved following training and experience in CBT were presented. Small group review of the frameworks and subsequent feedback demonstrated broad support for requirements of CBT knowledge and attitudinal competencies that could inform day-to-day practice, within a generic psychotherapeutic skills framework. New competencies that were related to CBT and considered meaningful in daily psychiatric practice emerged. Further development of these ideas from the workshop in this paper leads to a set of coherent competencies that would be helpful in non-CBT specialist practice and are congruent with the context of generic psychiatric practice. These enable models of training other than the delivery of a single ‘brief’ psychotherapy case to be considered.
SIX3 deletions and incomplete penetrance in families affected by holoprosencephaly

Holoprosencephaly (HPE) is failure of the forebrain to divide completely during embryogenesis. Incomplete penetrance has not been reported previously in SIX3 whole gene deletions, which are known to cause HPE. Both chromosomal microarray and whole exome sequencing (WES) were used to evaluate families with inherited HPE. Two families showed inherited deletions that contain SIX3 and were incompletely penetrant for HPE. Using WES, we ruled out parental mosaicism, a SIX3 hypomorph, and clinically significant variants in genes that are known to interact with SIX3 as causes of incomplete penetrance. We demonstrate the importance of molecular cascade testing in families with HPE and we answer important questions about incomplete penetrance.
Semantic Neighbor Graph Hashing for Multimodal Retrieval

Hashing methods have been widely used for approximate nearest neighbor search in recent years due to its computational and storage effectiveness. Most existing multimodal hashing methods try to preserve the similarity relationship based on either metric distances or semantic labels in a procrustean way, while ignoring the intra-class and inter-class variations inherent in the metric space. In this paper, we propose a novel multimodal hashing method, termed as semantic neighbor graph hashing (SNGH), which aims to preserve the fine-grained similarity metric based on the semantic graph that is constructed by jointly pursuing the semantic supervision and the local neighborhood structure. Specifically, the semantic graph is constructed to capture the local similarity structure for the image modality and the text modality, respectively. Furthermore, we define a function based on the local similarity in particular to adaptively calculate multi-level similarities by encoding the intra-class and inter-class variations. After obtaining the unified hash codes, the logistic regression with kernel trick is employed to learn view-specific hash functions independently for each modality. Extensive experiments are conducted on four widely used multimodal data sets. The experimental results demonstrate the superiority of the proposed SNGH method compared with the state-of-the-art multimodal hashing methods.
Efficient Network Measurements through Approximated Windows

Many networking applications require timely access to recent network measurements, which can be captured using a sliding window model. Maintaining such measurements is a challenging task due to the fast line speed and scarcity of fast memory in routers. In this work, we study the efficiency factor that can be gained by approximating the window size. That is, we allow the algorithm to dynamically adjust the window size between $W$ and $W(1+\tau)$ where $\tau$ is a small positive parameter. For example, consider the \emph{basic summing} problem of computing the sum of the last $W$ elements in a stream whose items are integers in $\{0,1\ldots,R\}$, where $R=\text{poly}(W)$. While it is known that $\Omega(W\log{R})$ bits are needed in the exact window model, we show that approximate windows allow an exponential space reduction for constant $\tau$. Specifically, we present a lower bound of $\Omega(\tau^{-1}\log(RW\tau))$ bits for the basic summing problem. Further, an $(1+\epsilon)$ multiplicative approximation of this problem requires $\Omega(\log({W/\epsilon}+\log\log{R}))$ bits for constant $\tau$. Additionally, for $RW\epsilon$ additive approximations, we show an $\Omega(\tau^{-1}\log\lfloor{1+\tau/\epsilon}\rfloor+\log({W/\epsilon}))$ lower bound~\footnote{ We also provide an optimal bound and algorithm for the $\tau<\epsilon$ case. }. For all three settings, we provide memory optimal algorithms that operate in constant time. Finally, we demonstrate the generality of the approximated window model by applying it to counting the number of distinct flows in a sliding window over a network stream. We present an algorithm that solves this problem while requiring asymptotically less space than previous sliding window methods when $\tau=O(1)$.
Novel Multi-Layer Network Decomposition boosting acceleration of multi-core algorithms

Complex networks are a technique for the modeling and analysis of large data sets in many scientific and engineering disciplines. Due to their excessive size conventional algorithms and single core processors struggle with the efficient processing of such networks. Employing multi-core graphic processing units (GPUs) could provide sufficient processing power for the analysis of such networks. However, commonly designed algorithms cannot exploit these massively parallel processing power for the analysis of such networks. In this paper, we present the Multi Layer Network Decomposition (MLND) approach which provides a general approach for parallel network analysis using multi-core processors via efficient partitioning and mapping of networks onto GPU architectures. Evaluation using a 336 core GPU graphic card demonstrated a 16x speed-up in complex network analysis relative to a CPU based approach.
Current Concepts of Fat Graft Survival: Histology of Aspirated Adipose Tissue and Review of the Literature

Background. Controversy remains about the longevity of correction in autologous fat grafts and its relation to adipocyte survival. Reported long‐term fat graft survival rates differ widely, depending on harvesting method, means of reinjection, injection site, and evaluation methods. Objective. To demonstrate histologic findings of aspirated adipose tissue and compare the findings to the reports in the literature. Methods. Review of the literature and the histology of transplanted fat 7 years after subcutaneous implantation and trypan blue staining to determine the vitality of defrosted adipocytes. Results. Fat cells survive aspiration with a suction machine or syringe equally well. Use of a liposuction cannula or 14‐gauge needle gives comparable results. Local anesthesia or tumescent local anesthesia is recommended for the donor site, preferably with addition of epinephrine. Conclusion. Clinical longevity of correction after autologous fat transfer is determined by the degree of augmentation resulting from the amount of fibrosis induced and the number of viable fat cells. Survival of aspirated fat cell grafts depends mainly on the anatomic site, the mobility and vascularity of the recipient tissue, or underlying causes and diseases, and less on harvesting and reinjection methods.
A multi-task optimization method based on event semantics in embedded wireless network

Many uncoordinated tasks often run in the same time in embedded wireless network, In this paper, we studied a task-sharing Optimization mechanism which is based on event semantics; discussed the definition, management and scheduling of the share structure on the bases of actor-oriented design method; described the event semantics system and signal types; at last given an example of multi-task Optimization in a logistics system.
Motor Nerve Arborization Requires Proteolytic Domain of Damage-Induced Neuronal Endopeptidase (DINE) during Development

Damage-induced neuronal endopeptidase (DINE)/endothelin-converting enzyme-like 1 (ECEL1) is a membrane-bound metalloprotease, which we originally identified as a nerve regeneration-associated molecule. Abundant expression of DINE is observed in regenerating neurons, as well as in developing spinal motor neurons. In line with this, DINE-deficient (DINE KO) embryos fail to arborize phrenic motor nerves in the diaphragm and to form proper neuromuscular junctions (NMJ), which lead to death shortly after birth. However, it is unclear whether protease activity of DINE is involved in motor nerve terminal arborization and how DINE participates in the process. To address these issues, we performed an in vivo rescue experiment in which three types of motor-neuron specific DINE transgenic mice were crossed with DINE KO mice. The DINE KO mice, which overexpressed wild-type DINE in motor neurons, succeeded in rescuing the aberrant nerve terminal arborization and lethality after birth, while those overexpressing two types of protease domain-mutated DINE failed. Further histochemical analysis showed abnormal behavior of immature Schwann cells along the DINE-deficient axons. Coculture experiments of motor neurons and Schwann cells ensured that the protease domain of neuronal DINE was required for proper alignment of immature Schwann cells along the axon. These findings suggest that protease activity of DINE is crucial for intramuscular innervation of motor nerves and subsequent NMJ formation, as well as proper control of interactions between axons and immature Schwann cells. SIGNIFICANCE STATEMENT Damage-induced neuronal endopeptidase (DINE) is a membrane-bound metalloprotease; expression is abundant in developing spinal motor neurons, as well as in nerve-injured neurons. DINE-deficient (KO) embryos fail to arborize phrenic motor nerves in the diaphragm and to form a neuromuscular junction, leading to death immediately after birth. To address whether proteolytic activity of DINE is involved in this process, we performed in vivo rescue experiments with DINE KO mice. Transgenic rescue of DINE KO mice was accomplished by overexpression of wild-type DINE, but not by protease domain-mutated DINE. Immature Schwann cells were abnormally aligned along the DINE protease-deficient axons. Thus, the protease activity of DINE is crucial for motor axon arborization, as well as the interaction between axons and immature Schwann cells.
Indonesian women’s blog formats from Tanah Betawi to Serambi Mekah: Women blogger’s choices of technical features

Drawing on the critiques of the active/passive dichotomy and using an ethnographic approach, this article looks at the forms of Indonesian women’s engagement in a convergent media world through blogging. We examine the technical, personalized authoring tools Indonesian women use in their blogging practices, and conclude that potential choices are not limitless as they hinge on authors’ contexts.
The Effects of Familial and Social Variables on Children's Educational Attainment

Throughout this project, the impact of variables such as income, family size, single vs. dual headed households, parents’ educational attainments and other background factors affecting the educational attainments of children in these families are examined. Additionally, the effect of children’s drug and alcohol use/ abuse on their education is examined. This article is available in The Park Place Economist: http://digitalcommons.iwu. edu/parkplace/vol10/iss1/11
How semantic category modulates preschool children’s visual memory

The dynamic interplay between perception and memory has been explored in preschool children by presenting filtered stimuli regarding animals and artifacts. The identification of filtered images was markedly influenced by both prior exposure and the semantic nature of the stimuli. The identification of animals required less physical information than artifacts did. Our results corroborate the notion that the human attention system evolves to reliably develop definite category-specific selection criteria by which living entities are monitored in different ways.
Identifying thread interference with performance variation

Understanding the performance of a multi-threaded appli- cation is difficult. The threads interfere when they access the same hardware resource, which slows down their execution. Unfortunately, current profiling tools are unable to identify the most problematic interference, because they cannot classify interference on different hardware resources. In this paper, we propose a holistic metric able to simultaneously classify inter- ference on different hardware resources. The metric considers performance variation as a universal indicator. We propose an interactive profiling tool to compute this metric. With an evaluation of 27 applications we show that our profiling tool successfully identify 10 performance bottlenecks caused by 6 different kinds of interference