Miracle-dz/UniFAR-FTUs huggingface dataset:
Proximal Femur Fractures After Free Vascularized Fibular Grafting to the Hip

The management of symptomatic femoral head osteonecrosis in young, active patients is troublesome and controversial. At the authors' institution, 707 consecutive free vascularized fibular grafts were performed for femoral head osteonecrosis between October 1979 and October 1995. Patients who underwent this procedure were at increased risk for proximal femur fractures because of the 16 to 21 mm core drilled through the lateral femoral cortex for removal of the avascular bone and placement of the fibular graft. An ongoing prospective database of patients who underwent this procedure was accessed to determine the incidence of and factors associated with postoperative subtrochanteric femur fractures. Eighteen subtrochanteric fractures occurred for an overall incidence of 2.5%. All fractures occurred through the core decompression site in the lateral femoral cortex. The treatment was nonoperative in seven patients and operative in 11. Fourteen of 18 fractures (77%) healed with an average of 4.1 months until radiographically documented union. Four fractures had nonunions develop, three of which later healed with bone grafting and internal fixation, whereas the fourth eventually required conversion to total hip arthroplasty. Twelve fractures in 251 patients occurred when the weightbearing regimen was touchdown weightbearing for the first 6 weeks and five fractures in 456 patients occurred when the weightbearing regimen was changed to nonweightbearing. The results indicate that nonweightbearing in the immediate postoperative period is associated with the lowest fracture rate.
Associations of physical fitness and academic performance among schoolchildren.

BACKGROUND Public schools provide opportunities for physical activity and fitness surveillance, but are evaluated and funded based on students' academic performance, not their physical fitness. Empirical research evaluating the connections between fitness and academic performance is needed to justify curriculum allocations to physical activity programs. METHODS Analyses were based on a convenience sample of 254,743 individually matched standardized academic (TAKS™) and fitness (FITNESSGRAM(®) ) test records of students, grades 3-11, collected by 13 Texas school districts. We categorized fitness results in quintiles by age and gender and used mixed effects regression models to compare the academic performance of the top and bottom fitness groups for each test. RESULTS All fitness variables except body mass index (BMI) showed significant, positive associations with academic performance after adjustment for socio-demographic covariates, with standardized mean difference effect sizes ranging from . 07 to . 34. Cardiovascular fitness showed the largest interquintile difference in TAKS score (32-75 points), followed by curl-ups. Additional adjustment for BMI and curl-ups showed dose-response associations between cardiovascular fitness and academic scores (p < .001 for both genders and outcomes). Analysis of BMI demonstrated limited, nonlinear association with academic performance after socio-demographic and fitness adjustments. CONCLUSIONS Fitness was strongly and significantly related to academic performance. Cardiovascular fitness showed a dose-response association with academic performance independent of other socio-demographic and fitness variables. The association appears to peak in late middle to early high school. We recommend that policymakers consider physical education (PE) mandates in middle high school, school administrators consider increasing PE time, and PE practitioners emphasize cardiovascular fitness.
Limits to Interfirm Coordination through Information Technology: Results of a Field Study in Consumer Packaged Goods Distribution

Researchers have suggested that information technology (IT) can reduce coordination costs, leading to increased coordination and cooperation among buyers and suppliers in an industry. However, improved coordination through IT, and the economic benefits from that coordination, may not be fully realized in practice; this conclusion is suggested by a field study in the consumer packaged goods industry investigating the impact of IT on interactions between manufacturers and retailers. New coordination mechanisms are emerging, driven by checkout scanner systems and IT, that permit more tightly coupled logistics operations in the distribution channel. The potential benefits of this increased coordination, through reduction in inventory and more stable manufacturing, are dramatic. However, we have observed considerable resistance by retailers to these innovations. Analysis of our field study results suggests that this resistance is due to the impact of the new coordination mechanisms on bargaining power; retailers perceive that their bargaining power will be eroded under the new coordination structure, and fear that this will preclude their sharing in the economic benefits.
A program to increase the number of family physicians in rural and underserved areas: impact after 22 years.

CONTEXT The shortage of physicians in rural areas is a longstanding and serious problem, and national and state policymakers and educators continue to face the challenge of finding effective ways to increase the supply of rural physicians. OBJECTIVE To determine the direct and long-term impact of the Physician Shortage Area Program (PSAP) of Jefferson Medical College (JMC) on the rural physician workforce. DESIGN Retrospective cohort study. PARTICIPANTS AND SETTING A total of 206 PSAP graduates from the classes of 1978 to 1991. MAIN OUTCOME MEASURES The PSAP graduates currently practicing family medicine in rural and underserved areas of Pennsylvania, compared with all allopathic medical school graduates in the state, and with all US and international allopathic graduates. All PSAP graduates were also compared with their non-PSAP peers at JMC regarding their US practice location, medical specialty, and retention for the past 5 to 10 years. RESULTS The PSAP graduates account for 21% (32/150) of family physicians practicing in rural Pennsylvania who graduated from one of the state's 7 medical schools, even though they represent only 1% (206/14710) of graduates from those schools (relative risk [RR], 19.1). Among all US and international medical school graduates, PSAP graduates represent 12% of all family physicians in rural Pennsylvania. Results were similar for PSAP graduates practicing in underserved areas. Overall, PSAP graduates were much more likely than their non-PSAP classmates at JMC to practice in a rural area of the United States (34% vs 11%; RR, 3.0), to practice in an underserved area (30% vs 9%; RR, 3.2), to practice family medicine (52% vs 13%; RR, 4.0), and to have combined a career in family practice with practice in a rural area (21% vs 2%; RR, 8.5). Of PSAP graduates, 84% were practicing in either a rural or small metropolitan area, or one of the primary care specialties. Program retention has remained high, with the number of PSAP graduates currently practicing rural family medicine equal to 87% of those practicing between 5 and 10 years ago, and the number practicing in underserved areas, 94%. CONCLUSIONS The PSAP, after more than 22 years, has had a disproportionately large impact on the rural physician workforce, and this effect has persisted over time. Based on these program results, policymakers and medical schools can have a substantial impact on the shortage of physicians in rural areas.
The Divergence of Long - and Short-run Effects of Manager's Shareholding on Bank Efficiencies in Taiwan

This paper adopts a panel error-correction model to explore dynamic impact of managerâ€™s shareholding on bank efficiencies by utilizing the pooled mean group. The sample comprises unbalanced panel data of 30 Taiwanese listed domestic commercial banks over the period 1998 to 2009. Empirical results show divergence of long- and short-run effects of managerâ€™s shareholding on bank efficiencies. The effect of managerâ€™s shareholding exerts a significantly positive effect on technical efficiency in the long run while coexisting with a negative short-run relationship. Conversely, increase in manager's shareholding leads to a reduction of scale efficiency in the long run whereas its short-run effect on scale efficiency is positive.
Asynchronous reproduction in three species of crocodilians in south-eastern Amazonia

ABSTRACT We studied reproduction of three species of crocodilians, Paleosuchus trigonatus, Caiman crocodilus and Melanosuchus niger, in the Xingu River, near the Belo Monte hydroelectric dam. The periods of laying and hatching of eggs were estimated for each nest before (2013–2014) and after (2016–2017) the river was dammed and the reservoir was formed. Nesting of the three species occurred between August and December, but was largely asynchronous; nest construction peaked in September for P. trigonatus, October for M. niger and November for C. crocodilus. Reservoir filling had little effect on the laying period of any of the species. Nests of P. trigonatus and M. niger were always within 0–12 m of the bank, whereas nests of C. crocodilus, which nests later in the season when flooding is more likely, were up to 100 m from the nearest water body. There was no relationship between distance from water and the number of eggs in nests, suggesting that larger and presumably more experienced females do not lay at different distances from the bank in any of the species.
Hip Fracture in Elderly Patients: Outcomes for Function, Quality of Life, and Type of Residence

A prospective study was done to investigate functional outcome, quality of life, and type of residence after hip fracture in patients 65 years of age and older. One hundred two patients admitted consecutively to a university and a general hospital were followed up as long as 4 months after admission. The mean age of the participants was 83 years; 58% of patients came from their own home, and 42% of patients came from institutions. Nearly 70% of patients had two or more diagnoses other than the hip fracture. Cumulative mortality was 20% at 4 months after fracture. Of surviving patients, 57% were back in their original situation for accommodation, 43% reached the same level of walking ability, and 17% achieved the same level of activities of daily living as before fracture. Patients experienced on average three complications, 26% of which were severe. Quality of life improved in the followup period of 4 months; however, the quality of life at 4 months was worse than the quality of life reported in a reference population. Average costs amounted to ε (Euro) 15.338 (which at the time was nearly equivalent to the US dollar) per patient, with nearly 50% of the costs attributable to hospital costs and 30% attributable to nursing home costs. The results of this study show a poor outcome after hip fracture in elderly patients.
Valuation Ratios and Stock Return Predictability in South Africa: Is It There?

Using monthly South African data for January 1990 through October 2009, this paper, to the best of our knowledge, is the first to examine the predictability of real stock return based on valuation ratios, namely, price-dividend and price-earnings ratios. We cannot detect either short-horizon or long-horizon predictability; that is, the hypothesis that the current value of a valuation ratio is uncorrelated with future stock price changes cannot be rejected at both short and long horizons based on bootstrapped critical values constructed from linear representations of the data. We find, via Monte Carlo simulations, that the power to detect predictability in finite samples tends to decrease at long horizons in a linear framework. Although Monte Carlo simulations applied to exponential smooth-transition autoregressive models of the price-dividend and price-earnings ratios show increased power, the ability of the nonlinear framework in explaining the pattern of stock return predictability in the data does not show any promise at either short or long horizons, just as in the linear predictive regressions.
How social context moderates the self-evaluative emotions experienced due to health risk behaviour

When people are confronted with the potential negative physical outcomes of their own health risk behaviour, they experience a self-threat. This threat is felt as negative self-evaluative emotions. We hypothesise that the threat will lead to more private self-evaluative emotions (e.g. regret) in a private social context, whereas more public self-evaluative emotions (e.g. embarrassment) will be felt in a public social context with negative norms. Consistent with our hypotheses, we show that participants anticipate feeling more private self-evaluative emotions when confronted with the negative consequences of their unhealthy behaviour when alone, and more public self-evaluative emotions when in a group (Study 1). They further anticipate more public self-evaluative emotions in response to a health self-threat when the group norm is negative, and more private self-evaluative emotions when the group norm is lenient (Study 2). Finally, in a cross-sectional study amongst smokers, we show that private but not public negative self-evaluative emotions concerning their own smoking habits are positively correlated with the intent to quit smoking (Study 3). These studies show that a distinction needs to be made between public and private self-evaluative emotions, in terms of their antecedents and effects. Theoretical implications and further lines of research are discussed.
Relationship between Vaccinia Virus Intracellular Cores, Early mRNAs, and DNA Replication Sites

ABSTRACT Virus assembly, a late event in the life cycle of vaccinia virus (VV), is preceded by a number of steps that all occur in the cytoplasm of the infected host cell: virion entry, delivery of the viral core into the cytoplasm, and transcription from these cores of early mRNAs, followed by the process of DNA replication. In the present study the quantitative and structural relationships between these distinct steps of VV morphogenesis were investigated. We show that viral RNA and DNA synthesis increases linearly with increasing amounts of incoming cores. Moreover, at multiplicities of infection that result in 10 to 40 cores per cell, an approximately 1:1 ratio between cores and sites of DNA replication exists, suggesting that each core is infectious. We have shown previously that VV early mRNAs collect in distinct granular structures that recruit components of the host cell translation machinery. Strikingly, these structures appeared to form some distance away from intracellular cores (M. Mallardo, S. Schleich, and J. Krijnse Locker, Mol. Biol. Cell 12:3875-3891, 2001). In the present study the intracellular locations of the sites of early mRNA accumulation and those of the subsequent process of DNA replication were compared. We show that these are distinct structures that have different intracellular locations. Finally, we study the fate of the parental DNA after core uncoating. By electron microscopy, cores were found close to membranes of the endoplasmic reticulum (ER) and the parental DNA, once it had left the core, appeared to associate preferentially with the cytosolic side of those membranes. Since we have previously shown that the process of DNA replication occurs in an ER-enclosed cytosolic “subcompartment” (N. Tolonen, L. Doglio, S. Schleich, and J. Krijnse Locker, Mol. Biol. Cell 12:2031-2046, 2001), the present data suggest that the parental DNA is released into the cytosol and associates with the same membranes where DNA replication is subsequently initiated. The combined data are discussed with respect to the cytosolic organization of VV morphogenesis.
Incidental Focal 18F-FDG Uptake in the Pituitary Gland: Clinical Significance and Differential Diagnostic Criteria

The purpose of this study was to identify the incidence and clinical significance of incidental pituitary uptake on whole-body 18F-FDG PET/CT. Methods: We evaluated 13,145 consecutive subjects who underwent 18F-FDG PET/CT. The final diagnosis of pathologic or physiologic uptake was based on brain MRI and follow-up PET scanning. Receiver-operating-characteristic curve analysis was performed to determine an optimal cutoff for detecting pathologic uptake. Results: We found that 107 (0.8%) subjects showed incidental pituitary uptake. In 29 of 71 subjects with the final diagnosis, the pituitary uptake was pathologic: macroadenomas (n = 21), microadenomas (n = 5), and malignancy (n = 3). When a maximum standardized uptake value of 4.1 was used as an optimal criterion for detecting pathologic uptake, the diagnostic sensitivity, specificity, and accuracy were 96.6%, 88.1%, and 91.5%, respectively. Conclusion: Although incidental pituitary uptake is an unusual finding, the degree of 18F-FDG accumulation is helpful in identifying pathologic pituitary lesions that warrant further diagnostic evaluation.
The competitive adsorption of multi-component VOCs on activated carbon

Four selected organics: benzene, toluene, ethyl acetate and acetone are used in the study which choose coconut carbon as adsorbent. Dynamic adsorption was used to measure the adsorption of the four organics' mix gas. Meanwhile, the study utilizes the extended Langmuir equation combined with the results of experiment which did by others to predict the result of the adsorption. The result of the study reveals that the adsorbabilities of the VOCs are different on AC. The adsorbability is amplified as the polarity and the boiling point of the VOCs amplifies. Otherwise the component whose adsorbability on AC is strong can replace the other component in the mix gas. This is just why the breakthrough curve of the component whose adsorbability on AC is weak has a peak. Compare the predict result of extended Langmuir equation with the result of the experimental we find that the prediction has a deviation with the experiment.
Theoretical Role of the Most Recent Prior Period’s Equity Price in Value Relevance Studies

This paper uses the Ohlson (1995) model and other related literature to theoretically demonstrate that the empirical specification of value relevance models with current or next period’s equity price as the dependent variable can be vastly improved when they utilize the most recent prior period’s equity price as an additional explanatory variable. The explanation further indicates that value relevance studies that use the Ohlson (1995) model should employ change in price or else returns, not the price level, as the dependent variable. These improvements to the empirical specification are shown to be important when past share price is highly correlated with important information that affects future earnings. This study reformulates the Ohlson (1995) value relevance model to demonstrate how it accommodates the most recent prior period equity price as an additional explanatory variable and also demonstrates how the earnings-based value relevance regression model equations can be used to improve the empirical specification for investigating the value relevance of an accounting variable.
Do the urinary bladder and large bowel interact, in sickness or in health?: ICI‐RS 2011

Normal functioning of the urinary bladder and the distal gut is an essential part of daily physiological activity coordinated by the peripheral and central nervous systems. Pathological changes in one of these organs may induce the development of cross‐organ sensitization in the pelvis and underlie clinical co‐morbidity of genitourinary and GI dysfunctions. Experimental human and animal data suggest that the bladder and distal colon interact under both normal and pathological conditions, however, the directions of these interactions can change dramatically depending on the nature and duration of the applied stimuli. This review article aimed to summarize the clinical data on colon–bladder cross‐reflexes in healthy individuals, as well as in patients with co‐morbid disorders. It also discusses currently used animal models, experimental approaches, and suggested mechanisms of colon–bladder cross‐talk. Additionally, it provides an overview of the potential pharmacological targets to develop treatment options for patients with co‐morbid disorders. Presented work resulted from the discussion of colon/bladder interactions during “Think Tank 9” presentations at the International Consultation on Incontinence Research Society meeting held in Bristol, UK, 2011. Neurourol. Urodynam. 31:352–358, 2012. © 2012 Wiley Periodicals, Inc.
Timing, Instructions, and Inhibitory Control: Some Missing Factors in the Age and Memory Debate

In response to Luszcz and Bryan, we point to three omitted factors that have been found to influence the presence and size of age differences in memory tasks and that, as such, have important implications for resolving theoretical questions about aging and memory. These include: (1) age differences in circadian rhythms and testing time effects that are associated with such differences; (2) instructions that may have a particularly disruptive effect on older adults, and (3) inhibitory control differences that have an age-related impact on both estimates of working memory span and on performance in multitask studies.
Voter Reaction to Government Incompetence and Corruption Related to the 1999 Earthquakes in Turkey

Two major earthquakes which struck northwestern Turkey in 1999 exposed rampant corruption involving construction and zoning code violations. The government's relief efforts were tainted by corruption as well, and exhibited a great deal of incompetence. How voters responded to these in the next election held in 2002 is investigated. The fact that different group of parties were responsible for the construction of the shoddy buildings, and for the corruption and mismanagement related to relief, provided us with a unique opportunity to determine whether and how the electorate punished the culprits for each of these. Vote equations are estimated for the seven major political parties. These are fitted to cross-provincial data individually, using OLS, Robust Regression methods, and Seemingly Unrelated Regressions procedures. The same picture emerges from each of these methods. Not just those ruling at the time of the earthquakes, but also other parties which were in power when the substandard buildings, were built were held accountable by the electorate. Furthermore, the Turkish voters appear to have allocated the blame rationally, taking into consideration the division of labor in the central government, and the relative influences the parties had on local administrations. Reaction of the voters to government incompetence and corruption was one of the factors which resulted in the emergence of a new party system. In 2002, the AKP, established only a year before, captured almost all of the far-right Islamist, about half of the far-right nationalist, and more than half of the center-right votes in 2002.
Robust Receding Horizon Control using Generalized Constraint Tightening

This paper presents a new form of robust Model Predictive Control (MPC) using constraint tightening, where the degree of tightening is a convex function of the feedback parameters. The proposed approach is shown to be able to represent a strictly larger class of feedback policies when compared to previous algorithms. Further analytical results provide a) necessary and sufficient conditions on the choice of feedback parameters for the existence of a nonempty output constraint set; and b) a sufficient condition for the existence of a nonempty robust invariant set. Combined with the convex parametrization, this enables an off-line linear optimization to determine the feedback policy that can tolerate much stronger disturbances while robustly satisfying the constraints. Simulation results are presented to highlight the advantages of the new control algorithm.