Miracle-dz/UniFAR-FTUs huggingface dataset:
On Distributed and Coordinated Resource Allocation for Interference Mitigation in Self-Organizing LTE Networks

We propose a distributed and coordinated radio resource allocation algorithm for orthogonal frequency division multiple access (OFDMA)-based cellular networks to self-organize efficient and stable frequency reuse patterns. In the proposed radio resource allocation algorithm, each cell independently and dynamically allocates modulation and coding scheme (MCS), resource block (RB), and transmit power to its users in a way that its total downlink (DL) transmit power is minimized, while users' throughput demands are satisfied. Moreover, each cell informs neighboring cells of the RBs that have been scheduled for its cell-edge users' DL transmissions through message passing. Accordingly, the neighboring cells abstain from assigning high transmit powers to the specified RBs. Extensive simulation results attempt to demonstrate that DL power control on a per-RB basis may play a key role in future networks, and show that the distributed minimization of DL transmit power at each cell, supported by intercell interference coordination, is able to provide a 20% improvement of network throughput, considerably reduce the number of user outages, and significantly enhance spatial reuse, as compared to cutting-edge resource allocation schemes.
Beautiful Friends and Ugly Strangers

Does the physical attractiveness of one's same sex peers affect the perceptions that others have of him or her? Subjects rated male or female targets who were either associated or unassociated with an attractive or unattractive same-sex other. Results indicated that targets were rated more positively when in the mere presence (unassociated) of an unattractive other and when associated by friendship with an attractive other. The results were interpreted as indicating the operation of two quite different processes, both based on physical attractiveness, underlying judgments of others.
In Vivo Cellular Tropism of Gorilla Simian Foamy Virus in Blood of Infected Humans

ABSTRACT Simian foamy viruses (SFV) are retroviruses that are widespread among nonhuman primates. SFV can be transmitted to humans, giving rise to a persistent infection. Only a few data are available concerning the distribution of SFV in human blood cells. Here we purified blood mononuclear cell subsets from 11 individuals infected with a Gorilla gorilla SFV strain and quantified SFV DNA levels by quantitative PCR. SFV DNA was detected in the majority of the CD8+, CD4+, and CD19+ lymphocyte samples and rarely in CD14+ monocyte and CD56+ NK lymphocyte samples. The median (interquartile range [IQR]) SFV DNA counts were 16.0 (11.0 to 49.8), 11.3 (5.9 to 28.3), and 17.2 (2.0 to 25.2) copies/105 cells in CD8+ T lymphocytes, CD4+ T lymphocytes, and CD19+ B lymphocytes, respectively. In the CD4 compartment, SFV DNA was detected in both memory and naive CD4+ T lymphocytes. SFV DNA levels in CD4+ T cells were positively correlated with the duration of the infection. Our study shows with a quantitative method that CD8+, CD4+, and B lymphocytes are major cellular targets of SFV in the blood of infected humans. IMPORTANCE Investigation of SFV infections in humans is important due to the origin of human immunodeficiency viruses (HIV) and human T cell lymphotropic viruses (HTLV) from cross-species transmission of their simian counterparts to humans. Surprisingly little is known about many aspects of the biology of SFV in infected humans, including quantitative data concerning the cellular targets of SFV in vivo. Here we show that the distribution of SFV DNA among the different leukocyte populations is not homogeneous and that viral load in CD4+ T lymphocytes is correlated with the duration of infection. These new data will help in understanding the biology of retroviral infections in humans and can be useful in the growing field of SFV-based gene therapy.
Lung recruitment in patients with the acute respiratory distress syndrome.

BACKGROUND In the acute respiratory distress syndrome (ARDS), positive end-expiratory pressure (PEEP) may decrease ventilator-induced lung injury by keeping lung regions open that otherwise would be collapsed. Since the effects of PEEP probably depend on the recruitability of lung tissue, we conducted a study to examine the relationship between the percentage of potentially recruitable lung, as indicated by computed tomography (CT), and the clinical and physiological effects of PEEP. METHODS Sixty-eight patients with acute lung injury or ARDS underwent whole-lung CT during breath-holding sessions at airway pressures of 5, 15, and 45 cm of water. The percentage of potentially recruitable lung was defined as the proportion of lung tissue in which aeration was restored at airway pressures between 5 and 45 cm of water. RESULTS The percentage of potentially recruitable lung varied widely in the population, accounting for a mean (+/-SD) of 13+/-11 percent of the lung weight, and was highly correlated with the percentage of lung tissue in which aeration was maintained after the application of PEEP (r2=0.72, P<0.001). On average, 24 percent of the lung could not be recruited. Patients with a higher percentage of potentially recruitable lung (greater than the median value of 9 percent) had greater total lung weights (P<0.001), poorer oxygenation (defined as a ratio of partial pressure of arterial oxygen to fraction of inspired oxygen) (P<0.001) and respiratory-system compliance (P=0.002), higher levels of dead space (P=0.002), and higher rates of death (P=0.02) than patients with a lower percentage of potentially recruitable lung. The combined physiological variables predicted, with a sensitivity of 71 percent and a specificity of 59 percent, whether a patient's proportion of potentially recruitable lung was higher or lower than the median. CONCLUSIONS In ARDS, the percentage of potentially recruitable lung is extremely variable and is strongly associated with the response to PEEP.
Computer simulation of gas molecular distribution in a cube container under molecular flow

Based on the cosine emission law which is one of the classical laws in the gas-kinetic theory, by the means of the computer simulation calculation, it is quantitatively proved that the molecular incidence rates and emission rate on the inner surfaces of a cube container are uneven distributed. In the case of dividing the one square surface into 100 units, both data and sketch show that the maximum unit incidence rate is 2.7% larger than the average value, whereas the minimum unit incidence rate is 5.7% smaller than the average value.
Birdsong: From behaviour to brain

Although vocal communication is wide-spread in animal kingdom, the use of learned (in contrast to innate) vocalization is very rare. We can find it only in few animal taxa: human, bats, whales and dolphins, elephants, parrots, hummingbirds, and songbirds. There are several parallels between human and songbird perception and production of vocal signals. Hence, many studies take interest in songbird singing for investigating the neural bases of learning and memory. Brain circuits controlling song learning and maintenance consist of two pathways — a vocal motor pathway responsible for production of learned vocalizations and anterior forebrain pathway responsible for learning and modifying the vocalizations. This review provides an overview of the song organization, its behavioural traits, and neural regulations. The recently expanding area of molecular mapping of the behaviour-driven gene expression in brain represents one of the modern approaches to the study the function of vocal and auditory areas for song learning and maintenance in birds.
Visual search and target-directed action

This research was supported by the Natural Sciences and Engineering Research Council of Canada. Experiment 2 was presented at the 1993 meeting of the Canadian Society for Brain, Behaviour, and Cognitive Science in Toronto and the 1993 meeting of the Psychonomic Society in Washington, D. C. We thank Umberto Castiello, Wolfgang Prinz, and Anne Treisman for their helpful comments and Quy Luong of Creative Visual Services (Communications Research Centre) for producing the data figures.
Alantolactone Induces Apoptosis and Cell Cycle Arrest on Lung Squamous Cancer SK‐MES‐1 Cells

Alantolactone, a sesquiterpene lactone compound, has variety of pharmacological properties, including anti‐inflammatory and antineoplastic effects. In our study, alantolactone inhibited cancer cell proliferation. To explore the mechanisms underlying its antitumor action, we further examined apoptotic cells and cell cycle distribution using flow cytometry analysis. Alantolactone triggered apoptosis and induced cell cycle G1/G0 phase arrest. Furthermore, the expressions of caspases‐8, ‐9, ‐3, PARP, and Bax were significantly upregulated, while antiapoptotic factor Bcl‐2 expression was inhibited. In addition, the expressions of cyclin‐dependent kinase 4 (CDK4), CDK6, cyclin D3, and cyclin D1 were downregulated by alantolactone. Therefore, our findings indicated that alantolactone has an antiproliferative role on lung squamous cancer cells, and it may be a promising chemotherapeutic agent for squamous lung cancer SK‐MES‐1 cells.
Matching Society Values: Students’ views of biotechnology

The rapid growth of biotechnology knowledge during the past decades has made it necessary to rethink the contents of the school curriculum and has provoked a consideration of the ethical and social issues related to the use of biotechnological applications. With the financial assistance of the European Union, the European Initiative for Biotechnology Education was set up to develop units for use in the member the countries, organize the translations of these between the many languages involved, organize in‐service courses for teachers, implement the materials in schools, as well as carrying out related research. This paper gives some findings of Spanish researchers when identifying and exploring the different cultural contexts in which biotechnology teaching and learning is embedded, being mainly concerned with the emerging attitudes and values of the students regarding such issues. After gathering information through case studies during the implementation phase, a questionnaire was developed in an interactive way by teachers and researchers in various stages, based on what students said. The results identify four main values: the “principle of the natural”, the “principle of the welfare”, the “principle of the technological solution” and the “principle of the individual decisions”. Their interaction and dichotomy are discussed, as well as the problems teachers face when having to deal with topics beyond those immediately related to science
TREC-3 Ad-Hoc, Routing Retrieval and Thresholding Experiments using PIRCS

The PIRCS retrieval system has been upgrated in TREC-3 to handle the full English collections of 2 GB in an efficient manner. For ad-hoc retrieval, we use recurrent spreading of activation in our network to implement query learning and expansion based on the best-ranked subdocuments of an initial retrieval. We also augment our standard retrieval algorithm with a soft-Boolean component. For routing, we use learning from signal-rich short documents or subdocument segments. For the optional thresholding experiment, we tried two approches to transforming retrieval status values (RSV's) so that they could be used to partition documents into retrieved and nonretrieved sets. The first method normalzies RSV's using a query self-retrieval score. The second, which requires training data, uses logistic regression to convert RSV's into estimates of probability of relevance. Overall, our results are highly competitive with those of other participants.
Dovepress Open Access to Scientific and Medical Research Open Access Full Text Article Anionic Linear-globular Dendrimer-cis-platinum (ii) Conjugates Promote Cytotoxicity in Vitro against Different Cancer Cell Lines Zohre Zarei Ghane

Due to their unique properties, Anticancer dendrimer-based drugs have been displaying promising results in both in vitro and in vivo in the treatment of cancerous cells, as compared to the traditional polymers. In this report, two conjugates (G1+Pt and G2+Pt) of cisplatin [cis-diaminedichloroplatinum; (CDDP)] with two generations (G1, G2) of a biocompatible anionic dendrimer were prepared in an aqueous media. Their potential cytotoxic effects, in two sensitive cancer cell lines HT1080 and CT26 together with one resistant cancer cell line SKOV3, using MTT (methyl thiazolyl tetrazolium) assay were examined. Hemolytic impacts and cell death mechanisms of the conjugates on human blood and HT1080 cell line were also investigated. The conjugate G2+Pt showed greater toxicity up to 9× and 2× in the sensitive and resistant cell lines (IC 50 comparison, inhibitory concentration) respectively when compared to the parent drug. The G1+Pt conjugate showed greater toxicity only in the sensitive HT1080 (2×) and CT26 (3.7×) cell lines. Moreover, the G1+Pt conjugate was less toxic approximately one third of the cisplatin in SKOV3 after 48 hrs of incubation. In summary, the G2+Pt conjugate had greater toxicity than the G1+Pt conjugate and cisplatin, based on the in vitro results. Approximately the same hemolysis behavior was observed for both conjugates and cisplatin. Both apoptosis and necrosis mechanisms (about 2× more than cisplatin) were attributed to conjugates and cisplatin in a direct correlation between the concentration and the degree of cell death. In conclusion, these conjugates with such high potency and minimum hemolysis would be suitable candidates for use against these cancerous cell lines as efficient and novel antitumor agents.
Evidence of negative energy balance using doubly labelled water in elite Kenyan endurance runners prior to competition

Previous studies have found Kenyan endurance runners to be in negative energy balance during training and prior to competition. The aim of the present study was to assess energy balance in nine elite Kenyan endurance runners during heavy training. Energy intake and expenditure were determined over 7d using weighed dietary intake and doubly labelled water, respectively. Athletes were on average in negative energy balance (mean energy intake 13 241 (SD 1330) kJ/d v. mean energy expenditure 14 611 (SD 1043) kJ/d; P=0·046), although there was no loss in body mass (mean 56·0 (SD 3·4) kg v. 55·7 (SD 3·6) kg; P=0·285). The calculation of underreporting was 13; (range −24 to +9%) and almost entirely accounted for by undereating (9% (range −55 to +39%)) as opposed to a lack of significant underrecording (i.e. total water intake was no different from water loss (mean 4·2 (SD 0·6) l/d v. 4·5 (SD 0·8) l/d; P=0·496)). Fluid intake was modest and consisted mainly of water (0·9 (SD 0·5) l/d) and milky tea (0·9 (SD 0·3) l/d). The diet was high in carbohydrate (67·3 (SD 7·8) %) and sufficient in protein (15·3 (SD 4·0) %) and fat (17·4 (SD 3·9) %). These results confirm previous observations that Kenyan runners are in negative energy balance during periods of intense training. A negative energy balance would result in a reduction in body mass, which, when combined with a high carbohydrate diet, would have the potential in the short term to enhance endurance running performance by reducing the energy cost of running.
Do Numbers Really Count? Group Threat Theory Revisited

A specific case of group threat theory states that the size of a given minority has a direct bearing on anti-immigrant attitudes amongst the majority, a hypothesis that has been shown to have some merit, especially in the USA. This article embarks on group threat theory by focusing on the actual as well as the perceived size of a minority under different political circumstances. Data are drawn from the European Social Survey. After using multilevel analysis for 20 European countries, the paper concludes that neither actual nor perceived size matter for anti-immigrant attitudes in Europe. Nor does size have any effect under different economic or political contexts. This challenges both the theoretical foundation of this specific case of group threat as well as the European political discourse that claims that immigration needs to be reduced in order to lessen tension and, in the long run, preserve a stable democracy.
Absent Does Not Equal Uninvolved: Predictors of Fathering in Teen Mother Families.

This study examines the effects of several predictors of father involvement in a large sample of single-parent, teen mother families. Ethological and role theories led to hypotheses of negative effects of the child's age and grandfather's presence and positive effects of the young man 's employment experience on his parenting. The data were from telephone surveys with adolescent female welfare recipients. Among the findings are that the work behavior of absent fathers had a significant direct effect on participation in childrearing and that minority mothers reported higher rates of paternal involvement.
An approximate stance map of the spring mass hopper with gravity correction for nonsymmetric locomotions

The Spring-Loaded Inverted Pendulum (SLIP) model has long been established as an effective and accurate descriptive model for running animals of widely differing sizes and morphologies, while also serving as a basis for several hopping robot designs. Further research on this model led to the discovery of several analytic approximations to its normally nonintegrable dynamics. However, these approximations mostly focus on steady-state running with symmetric trajectories due to their linearization of gravitational effects, an assumption that is quickly violated for locomotion on more complex terrain wherein transient, non-symmetric trajectories dominate. In this paper, we introduce a novel gravity correction scheme that extends on one of the more recent analytic approximations to the SLIP dynamics and achieves good accuracy even for highly non-symmetric trajectories. Our approach is based on incorporating the total effect of gravity on the angular momentum throughout a single stance phase and allows us to preserve the analytic simplicity of the approximation to support our longer term research on reactive footstep planning for dynamic legged locomotion. We compare the performance of our method in simulation to two other existing analytic approximations and show that it outperforms them for most physically realistic non-symmetric SLIP trajectories while maintaining the same accuracy for symmetric trajectories.
Nostril Differences in the Olfactory Performance in Health and Disease

In the past few decades, several olfactory tests have been developed to assess olfactory performance and detect disorders. Contrary to other sensory systems, both nostrils are usually tested together; we hypothesized that monorhinal testing may reveal side differences in sensitivity which may be useful for the diagnosis of olfactory dysfunction. Using the "Sniffin' Sticks" test, we assessed olfactory function of 458 participants (278 healthy controls, 180 hyposmic patients), one nostril after the other, with 3 different tasks. For each participant and each task, we compared the scores obtained with both nostrils, and defined the best and worst nostrils. Thus we were able to establish normative data and to define cut-off values. Our results suggest that scores obtained with the worst nostril are the most efficient in detecting an olfactory disorder. This supports the importance of monorhinal testing, as it can allow an earlier and more accurate diagnosis than birhinal testing. This may be especially useful in the context of early detection of neurodegenerative diseases.
Out-of-Domain Utterance Detection Using Classification Confidences of Multiple Topics

One significant problem for spoken language systems is how to cope with users' out-of-domain (OOD) utterances which cannot be handled by the back-end application system. In this paper, we propose a novel OOD detection framework, which makes use of the classification confidence scores of multiple topics and applies a linear discriminant model to perform in-domain verification. The verification model is trained using a combination of deleted interpolation of the in-domain data and minimum-classification-error training, and does not require actual OOD data during the training process, thus realizing high portability. When applied to the "phrasebook" system, a single utterance read-style speech task, the proposed approach achieves an absolute reduction in OOD detection errors of up to 8.1 points (40% relative) compared to a baseline method based on the maximum topic classification score. Furthermore, the proposed approach realizes comparable performance to an equivalent system trained on both in-domain and OOD data, while requiring no OOD data during training. We also apply this framework to the "machine-aided-dialogue" corpus, a spontaneous dialogue speech task, and extend the framework in two manners. First, we introduce topic clustering which enables reliable topic confidence scores to be generated even for indistinct utterances, and second, we implement methods to effectively incorporate dialogue context. Integration of these two methods into the proposed framework significantly improves OOD detection performance, achieving a further reduction in equal error rate (EER) of 7.9 points
Neoantigens on spontaneous and carcinogen‐induced rat tumours defined by in vitro lymphocytotoxicity assays

Lymph‐node cells from rats bearing tumours apparently lacking in tumour rejection antigens were cytotoxic in vitro for cultured tumour cells. The specificities of these reactions differed, however, from those demonstrated with immunogenic chemically‐induced rat tumours since cross‐reactivity was observed, especially between tumours of the same histological type. This was most clearly demonstrated in tests with rat mammary carcinomas where tumour‐bearer lymph‐node cells were cytotoxic for a range of mammary carcinomas including spontaneously arising and chemically‐induced tumours. The reactivities of tumour‐bearer lymph‐node cells could be blocked by pre‐treating target cells with serum of tumour‐bearing rats and also by sera of multiparous rats. Conversely, tumour‐bearer sera were highly effective in blocking embryo cells from attack by sensitized LNC from multiparous rats. The results suggest that antigens detected on these tumours by the in vitro assay were embryonic components which were immunogenic in the tumor‐bearing host, although they were not capable of inducing tumour‐rejection reactions in immunized rats.
Tragedy of the commons in the chemostat

We present a proof of principle for the phenomenon of the tragedy of the commons that is at the center of many theories on the evolution of cooperation. We establish the tragedy in the context of a general chemostat model with two species, the cooperator and the cheater. Both species have the same growth rate function and yield constant, but the cooperator allocates a portion of the nutrient uptake towards the production of a public good -the “Commons” in the Tragedy-which is needed to digest the externally supplied nutrient. The cheater on the other hand does not produce this enzyme, and allocates all nutrient uptake towards its own growth. We prove that when the cheater is present initially, both the cooperator and the cheater will eventually go extinct, hereby confirming the occurrence of the tragedy. We also show that without the cheater, the cooperator can survive indefinitely, provided that at least a low level of public good or processed nutrient is available initially. Our results provide a predictive framework for the analysis of cooperator-cheater dynamics in a powerful model system of experimental evolution.