Miracle-dz/UniFAR-FTUs huggingface dataset:
In-Depth Global Analysis of Transcript Abundance Levels in Porcine Alveolar Macrophages Following Infection with Porcine Reproductive and Respiratory Syndrome Virus

Porcine reproductive and respiratory syndrome virus (PRRSV) is a major pathogen of swine worldwide and causes considerable economic loss. Identifying specific cell signaling or activation pathways that associate with variation in PRRSV replication and macrophage function may lead to identification of novel gene targets for the control of PRRSV infection. Serial Analysis of Gene Expression (SAGE) was used to create and survey the transcriptome of in vitro mock-infected and PRRSV strain VR-2332-infected porcine alveolar macrophages (PAM) at 0, 6, 12, 16, and 24 hours after infection. The transcriptome data indicated changes in transcript abundance occurring in PRRSV-infected PAMs over time after infection with more than 590 unique tags with significantly altered transcript abundance levels identified (P < .01). Strikingly, innate immune genes (whose transcript abundances are typically altered in response to other pathogens or insults including IL-8, CCL4, and IL-1β) showed no or very little change at any time point following infection.
Long-Term Survival of Saplings during the Transformation to Continuous Cover

The Glentress Trial Area is an extensive research area in southern Scotland of 117 ha where a long-term trial of the transformation of even-aged plantations to continuous cover has been in progress since 1952. During the assessment of permanent sample plots in 1990 information on the species and spatial position of saplings (trees taller than 1.3 m with a diameter at breast height of < 7 cm) was recorded. This provided a unique opportunity to investigate the long-term survival of saplings during the transformation process when the Trial Area was reassessed in 2009. The main finding was that 37% of saplings survived the 19-year period and the majority developed into trees (≥7 cm diameter at breast height). There was considerable variation between species, the lowest survival of saplings was European larch (Larix decidua Mill.) (13%) and the highest European beech (Fagus sylvatica L.) (55%); however differences between species were not significant. There were, however, significant differences between the six management areas with three with high sapling survival (55% to 61%) but others much lower (27% to 32%). If this result is confirmed by other studies, covering a broader range of sites, management guidance that assumes 90% survival will need to be revised.
One Complex Wavelet Algorithm Based on Image Deconvolution

In this paper, a new method PRECGDT-CWT is advanced, using the standard DT-CWT filters of the (13-19) taps near orthogonal filters at level 1 together with the 14-tap Q-shift filters at levels not less than 2. We chose ten iterations of the conjugate gradient algorithm used with the preconditioned system search direction starting from a ward estimate. We also compare the results with alternative deconvolution algorithms. The method of PRECGDT-CWT performed better than all the other methods tested and better than the published results on similar deconvolution experiments. In summary, complex wavelets appear to provide a useful Bayesian image model that is both powerful and requires relatively little computation.
An Open versus Traditional Psychology Textbook: Student Performance, Perceptions, and Use

In the current study we examined students' course performance, perceptions, and self-reported use of an open textbook compared to a traditional publisher's textbook in an introductory psychology course. Sixty students from two course sections used either an open textbook or a traditional textbook. To minimize the effect of confounding variables, each section was taught by the same instructor, at the same time of day, using identical in-class materials, syllabi, and sequencing, on alternating days of the week. Course performance was measured by analyzing exam scores and final course grades. A 22-item survey was utilized at the end of the term to measure students' textbook perceptions and use. Findings revealed no significant differences in student course performance or textbook use across the two sections. Participants in both groups perceived cost, weight, and convenience as the biggest advantages of an open textbook and perceived ease of reading, convenience, ability to highlight and take notes, ability to quickly find a topic, and ability to keep as a reference as the biggest advantages of a traditional textbook. Finally, when asked to select which type of textbook they preferred, students in each section selected the textbook they were using. The implications of these findings are discussed.
Lessons Learned on Design for Modifiability and Maintainability

Maintainability is perhaps one of the most important aspects of software development in that maintenance costs account for at least 50% of software system lifetime costs. A common maintenance practice is adding new capabilities to satisfy the evolving system dynamics, thus contributing to the ever-growing expenses. This paper discusses some lessons learned from system modifiability that affect software maintainability from the design standpoint. Deciding which design approach is most appropriate for the underlying system requirements plays a major role in software product operability and extensibility. keywords: design for change, maintainability, modifiability, software IC.
Researcher-led academic development

ABSTRACT In this study, members of a higher education department explore their research activity and how it influences their practice as academic developers in a research-led institution. While the research activities of the team members appear diverse, they are all underpinned by a shared set of professional values to provide an anchor for these activities. Research-as-pedagogy and the relationship between the discourses of research and teaching are explored using Bernstein’s knowledge structures. The authors conclude that differences in research focus (horizontal discourse) provide dynamism across a department and that stability is provided through the underpinning core values inherent in the vertical discourse.
On modeling of random drift of MEMS gyroscope and design of Kalman filter

By virtue of lower price, smaller size and lighter weight than that of traditional rate sensors, the Micro-Electro-Mechanical System (MEMS) has been widely developed to use in low cost and miniaturized Inertial Measurement Units (IMU). However, the MEMS gyroscopes usually have large drift, which limit its use. In this paper, a one-order autoregressive (AR) model is built for the residual signal of gyroscope and Kalman filter with colored noise is designed. In order to verify the validity of the model and the filter, static test, rate test and oscillating test are designed. The test results demonstrate that the performance of MEMS gyroscope is improved remarkably when the body does not move with great flexibility and the effectiveness will come down when the flexibility of the body increases. Analysis has been done to illustrate the reasons for the phenomena. So the technique should be used with caution when the body move with great flexibility. From a navigation point of view, the effects demonstrated seem to be meaningful and could be shown, to the best of our knowledge, for the first time.
Local attitudes toward Apennine brown bears: Insights for conservation issues

Human‐carnivore coexistence is a multi‐faceted issue that requires an understanding of the diverse attitudes and perspectives of the communities living with large carnivores. To inform initiatives that encourage behaviors in line with conservation goals, we focused on assessing the two components of attitudes (i.e., feelings and beliefs), as well as norms of local communities coexisting with Apennine brown bears (Ursus arctos marsicanus) for a long time. This bear population is under serious extinction risks due to its persistently small population size, which is currently confined to the long‐established protected area of Abruzzo, Lazio and Molise National Park (PNALM) and its surrounding region in central Italy. We interviewed 1,611 residents in the PNALM to determine attitudes and values toward bears. We found that support for the bear's legal protection was widespread throughout the area, though beliefs about the benefits of conserving bears varied across geographic administrative districts. Our results showed that residents across our study areas liked bears. At the same time, areas that received more benefits from tourism were more strongly associated with positive feelings toward bears. Such findings provide useful information to improve communication efforts of conservation authorities with local communities.
Cis-regulatory code of stress-responsive transcription in Arabidopsis thaliana

Environmental stress leads to dramatic transcriptional reprogramming, which is central to plant survival. Although substantial knowledge has accumulated on how a few plant cis-regulatory elements (CREs) function in stress regulation, many more CREs remain to be discovered. In addition, the plant stress cis-regulatory code, i.e., how CREs work independently and/or in concert to specify stress-responsive transcription, is mostly unknown. On the basis of gene expression patterns under multiple stresses, we identified a large number of putative CREs (pCREs) in Arabidopsis thaliana with characteristics of authentic cis-elements. Surprisingly, biotic and abiotic responses are mostly mediated by two distinct pCRE superfamilies. In addition, we uncovered cis-regulatory codes specifying how pCRE presence and absence, combinatorial relationships, location, and copy number can be used to predict stress-responsive expression. Expression prediction models based on pCRE combinations perform significantly better than those based on simply pCRE presence and absence, location, and copy number. Furthermore, instead of a few master combinatorial rules for each stress condition, many rules were discovered, and each appears to control only a small subset of stress-responsive genes. Given there are very few documented interactions between plant CREs, the combinatorial rules we have uncovered significantly contribute to a better understanding of the cis-regulatory logic underlying plant stress response and provide prioritized targets for experimentation.
Astrophysical and cosmological information from large-scale submillimetre surveys of extragalactic sources

We present a quantitative analysis of the astrophysical and cosmological information that can be extracted from the many important wide-area, shallow surveys that will be carried out in the next few years. Our calculations combine the predictions of the physical model by Granato et al. for the formation and evolution of spheroidal galaxies with up-to-date phenomenological models for the evolution of starburst and normal late-type galaxies and of radio sources. We compute the expected number counts and the redshift distributions of these source populations separately and then focus on protospheroidal galaxies. For the latter objects, we predict the counts and redshift distributions of strongly lensed sources at 250, 350, 500 and 850 μm, the angular correlation function of sources detected in the surveys considered, and the angular power spectra due to clustering of sources below the detection limit in Herschel and Planck surveys. An optimal survey for selecting strongly lensed protospheroidal galaxies is described, and it is shown how they can be easily distinguished from the other source populations. We also discuss the detectability of the imprints of the one-halo and two-halo regimes on angular correlation functions and clustering power spectra, as well as the constraints on cosmological parameters that can be obtained from the determinations of these quantities. The novel data relevant to derive the first submillimetre estimates of the local luminosity functions of starburst and late-type galaxies, and the constraints on the properties of rare source populations, such as blazars, are also briefly described.
FoxQ1 Promotes Glioma Cells Proliferation and Migration by Regulating NRXN3 Expression

Background Forkhead box Q1 (FoxQ1) is a member of the forkhead transcription factor family, and it has recently been found to participate in cancer development. However, whether FoxQ1 expression contributes to glioma development and progression is not known. We investigate FoxQ1 expression in gliomas and the role of FoxQ1 during tumorgenesis. Methods Reverse transcription quantitative real-time PCR (RT-qPCR) and Western blot were used to determine the FoxQ1 and Neurexins 3 (NRXN3) expression in gliomas. Chromatin immunoprecipitation (ChIP) and luciferase assays were used to determine the regulation between FoxQ1 and NRXN3. We established depleted FoxQ1 stable clones in U-87MG cells and overexpressed FoxQ1 stable clones in SW1088 cells. MTT and transwell were used to evaluate the ability of proliferation and migration, respectively. Results FoxQ1 mRNA and protein were up-regulated in gliomas and negatively related to the NRXN3 expression (r = −0.373, P = 0.042). FoxQ1 directly binds to NRXN3 promoter region and suppresses the promoter activity. Furthermore, the ability of proliferation and migration is reduced in depleted FoxQ1 cells. Conclusion FoxQ1 promotes glioma cell proliferation and migration by down-regulation of NRXN3 expression.
AGEinG And LifE CoursE , fAmiLy And Community HEALtH WHo Global report on falls Prevention in older Age

The designations employed and the presentation of the material in this publication do not imply the expression of any opinion whatsoever on the part of the World Health Organization concerning the legal status of any country, territory, city or area or of its authorities, or concerning the delimitation of its frontiers or boundaries. Dotted lines on maps represent approximate border lines for which there may not yet be full agreement. The mention of specific companies or of certain manufacturers' products does not imply that they are endorsed or recommended by the World Health Organization in preference to others of a similar nature that are not mentioned. Errors and omissions excepted, the names of proprietary products are distinguished by initial capital letters. All reasonable precautions have been taken by the World Health Organization to verify the information contained in this publication. However, the published material is being distributed without warranty of any kind, either expressed or implied. The responsibility for the interpretation and use of the material lies with the reader. in no event shall the World Health Organization be liable for damages arising from its use.
A Near Fair User Scheduling Scheme in Cognitive Radio Networks

Nowadays, cognitive radio technique has been acknowledged as a smart and potential method to improve the spectrum utilization. In this work, we investigate a cognitive radio communication scheme, where a number of cognitive users, each with multiple antennas, can share the spectrum with the primary user. To decrease the inter-user interference, zero-forcing beamforming (ZFBF) is considered. We presented a design of three-step selection for both the cognitive users and their antennas at receiver. In the first step of the studied scheme, antennas-selection is performed to based on a certain algorithm and then user-selection is performed based on Proportional Fair algorithm. Next the active set of cognitive users is selected according to the correlation between the users in the third step. Simulation results show that at the expense of some sum-rate loss, our proposed scheme can realize near fair resource allocation among the cognitive users as well as the decrease of the interference to the primary user and of the feedback.
Optimal Binary Space Partitions for Segments in the Plane

An optimal BSP for a set S of disjoint line segments in the plane is a BSP for S that produces the minimum number of cuts. We study optimal BSPs for three classes of BSPs, which differ in the splitting lines that can be used when partitioning a set of fragments in the recursive partitioning process: free BSPs can use any splitting line, restricted BSPs can only use splitting lines through pairs of fragment endpoints, and auto-partitions can only use splitting lines containing a fragment. We obtain the following two results: • It is NP-hard to decide whether a given set of segments admits an auto-partition that does not make any cuts. • An optimal restricted BSP makes at most 2 times as many cuts as an optimal free BSP for the same set of segments.
TOPICAL REVIEW: Micro-Raman spectroscopy to study local mechanical stress in silicon integrated circuits

Local mechanical stress is currently an important topic of concern in microelectronics processing. A technique that has become increasingly popular for local mechanical stress measurements is micro-Raman spectroscopy. In this paper, the theoretical background of Raman spectroscopy, with special attention to its sensitivity for mechanical stress, is discussed, and practical information is given for the application of this technique to stress measurements in silicon integrated circuits. An overview is given of some important applications of the technique, illustrated with examples from the literature: the first studies of the influence of external stress on the Si Raman modes are reviewed; the application of this technique to measure stress in silicon-on-insulator films is discussed; results of measurements of local stress in isolation structures and trenches are reviewed; and the use of micro-Raman spectroscopy to obtain more information on stress in metals, by measuring the stress in the surrounding Si substrate is explained.
Two Data Sets for Tempo Estimation and Key Detection in Electronic Dance Music Annotated from User Corrections

We present two new data sets for automatic evaluation of tempo estimation and key detection algorithms. In contrast to existing collections, both released data sets focus on electronic dance music (EDM). The data sets have been automatically created from user feedback and annotations extracted from web sources. More precisely, we utilize user corrections submitted to an online forum to report wrong tempo and key annotations on the Beatport website. Beatport is a digital record store targeted at DJs and focusing on EDM genres. For all annotated tracks in the data sets, samples of at least one-minute-length can be freely downloaded. For key detection, further ground truth is extracted from expert annotations manually assigned to Beatport tracks for benchmarking purposes. The set for tempo estimation comprises 664 tracks and the set for key detection 604 tracks. We detail the creation process of both data sets and perform extensive benchmarks using state-of-theart algorithms from both academic research and commercial products.
MIMO Subband Volterra Digital Predistortion for Concurrent Aggregated Carrier Communications

This paper presents a multiple-input multiple-output (MIMO) nonlinear mitigation technique for closely spaced concurrent aggregated carrier systems. The transmitter architecture considers band-limited sources, where the predistorter and signal bandwidth are the same, thus reducing transmitter hardware cost and power consumption. The technique relies on multirate processing and linear filtering and uses the carrier frequencies to isolate the contribution of linear and nonlinear basis functions to the desired bands. This approach can be used with any MIMO model structure. In particular, models are linear in the parameters of low computational complexity. The technique was evaluated using three concurrent carriers of 50 MHz each fed to a Doherty amplifier. The results show significant reduction in the error vector magnitude and improvements for the transmitter efficiency using the proposed compensation technique.
Fluxes, brane charges and Chern morphisms of hyperbolic geometry

The purpose of this paper is to provide the reader with a collection of results which can be found in the mathematical literature and to apply them to hyperbolic spaces that may have a role in physical theories. Specifically, we apply K-theory methods for the calculation of brane charges and RR-fields on hyperbolic spaces (and orbifolds thereof). It is known that by tensoring K-groups with the rationals, K-theory can be mapped to rational cohomology by means of the Chern character isomorphisms. The Chern character allows one to relate the analytic Dirac index to a topological index, which can be expressed in terms of cohomological characteristic classes. We obtain explicit formulae for Chern character, spectral invariants, and the index of a twisted Dirac operator associated with real hyperbolic spaces. Some notes for a bivariant version of topological K-theory (KK-theory) with its connection to the index of the twisted Dirac operator and twisted cohomology of hyperbolic spaces are given. Finally, we concentrate on lower K-groups useful for description of torsion charges.
On induced Folkman numbers

In 1970, Folkman proved that for any graph G there exists a graph H with the same clique number as G. In addition, any r ‐coloring of the vertices of H yields a monochromatic copy of G. For a given graph G and a number of colors r let f(G, r) be the order of the smallest graph H with the above properties. In this paper, we give a relatively small upper bound on f(G, r) as a function of the order of G and its clique number. © 2012 Wiley Periodicals, Inc. Random Struct. Alg. , 40, 493–500, 2012
Presentation, force estimation and control of an instrumented platform dedicated to automated micromanipulation tasks

This paper presents a platform used to measure micromanipulation forces. The main interest of the proposed platform is that it uses classical force sensors with limited range and adapts these sensors to that of micromanipulation forces. The proposed platform, and an additional micropositioning device, are afterwards used to develop a micromanipulation system. To automate this system, we design two control levels. First, an internal loop with a PID controller is employed to improve the micropositioning device's performances. Then, an external loop based on an incremental control law is implemented to control the force. The automated system is finally used for the micromanipulation task on rigid and non-rigid micro-objects.
Cache Miss Characterization in Hierarchical Large-Scale Cache-Coherent Systems

There is a growing trend towards developing large-scale cache-coherent systems by using commodity symmetric multiprocessors, which requires to extend their coherence protocol. In such systems, cache coherence transactions issued due to cache misses traverse interconnection networks with very different topologies and latencies. In this work, we perform a cache miss characterization aimed at analyzing the benefits that can be expected for a specialized coherence controller able to locally resolve cache misses, thus saving traffic across long-latency links. Results show that there is a high potential in reducing miss latency in these systems, and that this potential reduction grows as the number of nodes in the system increases. Particularly, in a system with just two boards 40% of the cache misses do not need the expensive inter-board communication. This percentage can increase up to 67.5% for an 8-board system.