Miracle-dz/UniFAR-FTUs huggingface dataset:
Heterogeneity of DSM-IV major depressive disorder as a consequence of subthreshold bipolarity.

CONTEXT There is growing evidence that major depressive disorder (MDD) might be overdiagnosed at the expense of bipolar disorder (BPD). OBJECTIVES To identify a subgroup of subthreshold BPD among DSM-IV MDD, which is distinct from pure MDD regarding a range of validators of bipolarity, and to examine the pattern of these validators among different groups with affective disorders. DESIGN Ten-year prospective longitudinal and family study including 3 follow-up waves. Data were assessed with the DSM-IV Munich Composite International Diagnostic Interview. SETTING Community sample in Munich, Germany. PARTICIPANTS A total of 2210 subjects (aged 14-24 years at baseline) who completed the third follow-up. MAIN OUTCOME MEASURES Cumulative incidence of pure MDD, BPD, and subthreshold BPD (defined as fulfilling criteria for MDD plus having manic symptoms but never having met criteria for [hypo]mania). RESULTS Among 488 respondents with MDD, 286 (58.6%) had pure MDD and 202 (41.4%) had subthreshold BPD (cumulative incidence, 9.3%). Compared with respondents who had pure MDD, respondents with subthreshold BPD were found to have a significantly increased family history of mania, considerably higher rates of nicotine dependence and alcohol use disorders, rates of panic disorder that were twice as high, and a tendency toward higher rates of criminal acts. Prospective analyses showed that subthreshold BPD converted more often into BPD during follow-up, with DSM-IV criterion D (symptoms observable by others) being of critical predictive relevance. With increasing severity of the manic component, rates for diverse validators accordingly increased (eg, alcohol use disorders, parental mania) or decreased (harm avoidance). CONCLUSIONS Data suggest that MDD is a heterogeneous concept including a large group with subthreshold BPD, which is clinically significant and shares similarities with BPD. Findings might support the need for a broader concept and a more comprehensive screening of bipolarity, which could be substantial for future research and adequate treatment of patients with bipolarity.
RETRACTION: How blockchain-timestamped protocols could improve the trustworthiness of medical science

[This retracts the article DOI: 10.12688/f1000research.8114. 1. ][This retracts the article DOI: 10.12688/f1000research.8114. 2. ][This retracts the article DOI: 10.12688/f1000research.8114. 3. ].
Effect of blinded peer review on abstract acceptance.

CONTEXT Peer review should evaluate the merit and quality of abstracts but may be biased by geographic location or institutional prestige. The effectiveness of blinded peer review at reducing bias is unknown. OBJECTIVE To evaluate the effect of blinded review on the association between abstract characteristics and likelihood of abstract acceptance at a national research meeting. DESIGN AND SETTING All abstracts submitted to the American Heart Association's annual Scientific Sessions research meeting from 2000-2004. Abstract review included the author's name and institution (open review) from 2000-2001, and this information was concealed (blinded review) from 2002-2004. Abstracts were categorized by country, primary language, institution prestige, author sex, and government and industry status. MAIN OUTCOME MEASURE Likelihood of abstract acceptance during open and blinded review, by abstract characteristics. RESULTS The mean number of abstracts submitted each year for evaluation was 13,455 and 28.5% were accepted. During open review, 40.8% of US and 22.6% of non-US abstracts were accepted (relative risk [RR], 1.81; 95% confidence interval [CI], 1.75-1.88), whereas during blinded review, 33.4% of US and 23.7% of non-US abstracts were accepted (RR, 1.41; 95% CI, 1.37-1.45; P<.001 for comparison between peer review periods). Among non-US abstracts, during open review, 31.1% from English- speaking countries and 20.9% from non-English-speaking countries were accepted (RR, 1.49; 95% CI, 1.39-1.59), whereas during blinded review, 28.8% and 22.8% of abstracts were accepted, respectively (RR, 1.26; 95% CI, 1.19-1.34; P<.001). Among abstracts from US academic institutions, during open review, 51.3% from highly prestigious and 32.6% from nonprestigious institutions were accepted (RR, 1.57; 95% CI, 1.48-1.67), whereas during blinded review, 38.8% and 29.0% of abstracts were accepted, respectively (RR, 1.34; 95% CI, 1.26-1.41; P<.001). CONCLUSIONS This study provides evidence of bias in the open review of abstracts, favoring authors from the United States, English-speaking countries outside the United States, and prestigious academic institutions. Moreover, blinded review at least partially reduced reviewer bias.
Co-design of on-chip antennas and circuits for a UNII band monolithic transceiver

The surge of highly integrated and multifunction wireless devices has necessitated the designers to think outside the box for solutions that are unconventional. The new trends have provided the impetus for low cost and compact RF System-on-Chip (SoC) approaches [1]. The major advantages of SoC are miniaturization and cost reduction. A major bottleneck to the true realization of monolithic RF SoC transceivers is the implementation of on-chip antennas with circuitry. Though complete integrated transceivers with on-chip antennas have been demonstrated, these designs are generally for high frequencies. Moreover, they either use non-standard CMOS processes or additional fabrication steps to enhance the antenna efficiency, which in turn adds to the cost of the system [2–3]. Another challenge related to the on-chip antennas is the characterization of their radiation properties. Most of the recently reported work (summarized in Table I) shows that very few on-chip antennas are characterized. Our previous work [4], demonstrated a Phase Lock Loop (PLL) based transmitter (TX) with an on-chip antenna. However, the radiation from the on-chip antenna experienced strong interference due to 1) some active circuitry on one side of the chip and 2) the PCB used to mount the chip in the anechoic chamber. This paper presents, for the first time, a complete 5.2 GHz (UNII band) transceiver with separate TX and receiver (RX) antennas. To the author's best knowledge, its size of 3 mm2 is the smallest reported for a UNII band transceiver with two on-chip antennas. Both antennas are characterized for their radiation properties through an on-wafer custom measurement setup. The strategy to co-design on-chip antennas with circuits, resultant trade-offs and measurement challenges have also been discussed.
Multiclass detect of current steganographic methods for JPEG format based re-stegnography

The aim of this paper is to properly classify various stego images of JPEG to their own stegnographic methods (current steganographic methods, such as F5, OutGuess, Steghide, JPhide and Jsteg). Although some Multiclass Detection methods had been previously published by the authors, they all had various limitations and disadvantages. First, models of some detect methods are too complicated, and their process are too fussy. Second, the performance of some detect methods could decline when the embed rate minish. Based on re-stegnography, the detection of this paper's algorithm extracts 109-dimensions features and trains SVM(support vector machine) multiclassifiers to classify all kinds of stego images and cover images with very high precisions (approximately 100%). Not only the model is very simple, but the performance is all the same excellent when the embed rate minish.
Localization and release of neurophysins.

The theory of neurosecr etion put forward by Bargmann & Scharrer (6) was based on the concept that the peptide hormones, oxytocin and vasopressin, were synthesiz ed in hypothalamic nuclei, packaged into neurosecretory vesicles, and conveyed by axonal transport to nerve termin als in the neural lobe of the pituitary gland whence they were released into the circulation by appropriate physiologic stimuli. The theory was developed from ana­ tomic studies using the technique of Gomori (38) to demonstrate that the central nervous system combined neural and endocrine functions. Barg­ mann (4, 5) observed that the acid-p ermanganate chrom-alum-haema
Inclusion detection with haptic-palpation system for medical telediagnosis

Detection of abnormalities in subcutaneous tissue is an important issue in medical diagnosis. Surgeons palpate this type of tissue to perceive pathologies through haptic sensation. This paper presents the framework of a real-time haptic-palpation system with inclusion detection to manipulate biological soft tissues and perceive their structures and material properties non-invasively. A user with a haptic device guides a robotic manipulator to perform palpation tasks and can detect the location of inclusions inside a soft medium (silicone-molded tissue phantom). For the objective measurement of the depth of the inclusion, a finite element (FE) model was developed to predict the reaction forces for various inclusion depths. The methods presented in this paper can be applied to the early detection of prostate cancer or breast cancer in telediagnosis.
Acquisition of learning processing in a navigation task using a functional parts combination model

In past studies of intelligent systems for problem solving, the internal structure of the system that determines the output for problem solving, that is, the computation process, is confined to the process built in by the designer. Thus, the program must be rewritten manually, even for a problem of similar type which can be handled by modifications. To deal with this point, we propose the functional parts combination (FPC) model, which can acquire different computation processes according to the individual problem. With the navigation of a mobile agent as a sample problem, the search power of the FPC model for the computation process is demonstrated by computer simulation for the case in which systems with different structures are applied to the same problem, and for the case in which a system with the same structure is applied to multiple problems. © 2006 Wiley Periodicals, Inc. Syst Comp Jpn, 37(4): 64–76, 2006; Published online in Wiley InterScience (). DOI 10.1002sscj. 20272
Isolation and characterization of the alpha platelet-derived growth factor receptor from rat olfactory epithelium

We have cloned and characterized a new member of the receptor tyrosine kinase family. The cDNA clone, isolated from a rat olfactory cDNA library, has considerable homology to the family of receptors that includes the colony-stimulating factor 1 receptor, the c-kit proto-oncogene, and the platelet-derived growth factor (PDGF) receptors. Analysis of DNA sequence homology, ligand-binding, and ligand-stimulated phosphorylation data suggests that this clone encodes the rat PDGF-A/B or alpha-receptor. Comparison of its sequence to those of other receptors allows us to postulate a mechanism for receptor dimerization and activation. The expression of the rat alpha-PDGF receptor in nonneuronal cells of the olfactory epithelium and in the olfactory bulb is consistent with a role for PDGF in glial cell generation.
Corrélats neuroanatomiques des systèmes de perception et de production des voyelles du Français

Recent neurobiological studies argue for a tight connection between speech perception and production systems. By means of functional magnetic resonance imaging, we here investigated whether common sensorimotor brain areas might participate in both vowel perception and production. A conjunction analysis between speaking and listening conditions showed a shared neural network with common activations observed in the left inferior frontal gyrus and in the superior temporal gyrus bilaterally. Direct comparisons between the two tasks also revealed specific modulated responses within the superior temporal and supramarginal gyri. These results provide evidence for sensory-to-motor and motor-to-sensory feedback control mechanisms during vowel perception and production.
A Fast Surface-Based Visual Hull Reconstruction

In this paper, we describe a new method for shape reconstruction from a set of silhouette images. We propose a method for traversing the depth layers of the projected viewing cones from all viewpoints based on the principle of the Constructive Solid Geometry (CSG). Taking advantage of the modern Graphics Processing Units (GPU), the proposed CSG-like method achieves a fast full reconstruction of VH, rather than rendering a looking of the VH from a virtual viewpoint, in an interactive frame rate. For each viewpoint, the viewing edges are computed separately in a parallel manner. Subsequently, the edges are merged together to generate the final surface-based Visual Hull (VH). The method was tested on several datasets including real data and the results will be presented in this paper.
Minimizing Workplace Gender and Racial Bias

WILLIAM T. BIELBY University of California, Santa Barbara bielbyw@Rsssf: ucsb. ed u Assessment of Yob Applicants. " Social Psychology Quarterly 57: 326-339. Glass, Xennifer. 2000. "Envisioning the Integration of Family and SVork: Toward a Kinder, Gentler Workplace. " Contemporary Sociology 29: 129-43. Harrod, Wendy J. 1980. "Expectations from Unequal Rewards. " Social Psychology (;2uarterly 43: 126-30. Hochschild, Arlie R. 1997. The Time Bind: When Work Becomes Home and Home Becomes Work. New York: Metropolitan Books. Kessler, Suzanne and Wendy McKenna. 1978. Gender: An Ethnomethodological Approach. New York: Wiley. Lorber, Yudith. 1994. Paradoxes of Gender. New Haven, CT: Yale University Press. Major, Brenda. 1989. "Gender Differences in Comparisons and Entitlement: Implication for Comparable Worth. " Joumal of Social lssues 45: 99-115. Markovsky, Barry, LeRoy F. Smith, and Joseph Berger. 1984. "Do Status Interventions Persist? " American Sociological Review 49: 373-82. Miller, Dale T. and W. Turnbull. 1986. "Expectancies and Interpersonal Processes. " Annual Review of Psychology 37: 233-56. Pugh, Meredith D. and Ralph Wahrman. 1983. "Neutralizing Sexism in Mixed<Sex Groups: Do Women Have to Be Better than Men? " American Journal of Sociology 88: 746-62. Ridgeway, Cecilia L. 1982. "Status in Groups: The Importance of Motivation. " American Sociological Review 47: 76-88. 1991. "The Social Construction of Status Value: Gender and Other Nominal Characteristics. " Social Forces 70:367-386. 1993. "Gender, Status, and the Social Psychology of Expectations. " Pp. 175-98 in Theory on Gender/Feminism on Theory, edited by Paula England. Hawthorne, NY: Aldine de Gruyter. 1997. "Interaction and the Conservation of Gender Inequality: Considering Employment. " American Sociological Review 62: 218-35. Ridgeway, Cecilia L. and Lynn Smith<Lovin. 1999. "The Gender System and Interaction. " Annual Review of Sociology 25: 191-216. Risman, Barbara J. 1998. Gender Vertigo. New Haven, CT: Yale University Press. Sewell, William H. 1992. "A Theory of Structure: Duality, Agency, and Transformation. " American Journal of Sociology 98: 1-29. Stangor, Charles, Laure Lynch, Changming Duan, and Beth Glass. 1992. "Categorization of Individuals on the Basis of Multiple Social Features. " Journal of Personality and Social Psychology 62: 207-18. Stewart, Penni, and James Moore. 1992. "Wage Disparities and Performance Expectations. " Social Psychology Quarterly 55: 78-85. Tetlock, Phillip E. 1983. "Accountability and Complexity of Thought. " Journal of Personality and Social Psychology 45: 74-83. Wagner, David G. and Joseph Berger. 1997. "Gender and Interpersonal Task Behaviors: Status Expectation Accounts. " Sociological Perspectives 40: 1-32. West, Candance and Don Zimmerman. 1987. "Doing Gender. " Gender and Society 1: 125-51. Williams, Yohn E. and Deborah L. Best. 1990. Measuring Sex Stereotypes: A Multinational Study. Newbury Park, CA: Sage.
Acyclic Pyrazolo[3,4-d]Pyrimidine Nucleoside as Potential Leishmaniostatic Agent

A new synthesis of 6-amino-1-hydroxyethoxymethyl-4 (5H)-oxopyrazolo[3, 4]pyrimidine (4) has been mentioned. Compound 4 exhibited inhibition of amastigotes of Leishmania donovani to the extent of 89% at 30 μg/mL, whereas iso-guanine analogue 5 had the inhibition only to the extent of 52.8% at 100 μg/mL in vitro. In hamster model the maximum inhibitory response for compound 4 against amastigotes multiplication was observed to be 94% at 50 mg/kg single dose for 5 consecutive days. *CDRI Communication no. 6522.
The benefits and challenges of electronic Data interchange(Implementation and application atn Kilindini Water Front project in Kenya)

Many organizations are applying Electronic Data Interchange (EDI) to improve operational efficiency, enhance information quality, and achieve reductions in processing time of critically important business information. EDI today represents an opportunity to improve business processes and business controls directly even though challenges are expected. It is in light of the opportunities and challenges that this study is done, specifically focusing on the benefits and challenges of implementation and application of EDI in Kenya considering the case of Kilindini Waterfront Project. Data was collected from 45 managers of the firms selected using convenient sampling. The respondents were asked about perceived benefits of EDI application and perceived challenges of EDI implementation and application. The questionnaires were mainly hand delivered to the respondents. The data collected was analyzed with the use of frequency tables, proportion, percentages, cross tabulations and factor analysis using SPSS. Majority of the firms that were studied had less than 1,000 employees which may possibly mean the firms are less labor intensive and therefore relying more on automated processes. This study also show that most of the respondents were experienced with EDI implementation and application and therefore had the necessary knowledge sought for. From the factor analysis carried out on the variables of the benefits of EDI application, the deduction drawn indicates that firms that apply EDI benefited. Some of the benefits include reduced errors, access to information, enhanced competitive capacity and improved trading partner relationship. Despite the benefits of EDI application, it was also found that there are several challenges encountered in the implementation of EDI. From the factor analysis carried out on the variables of the challenges in the EDI implementation, the deduction drawn indicates some of the challenges to be lack of top management support, negative staff attitude, inadequate IT staff training and inadequate non IT staff training. This study also indicated that there were challenges encountered in the application of EDI. From the factor analysis carried out on the variables of the challenges of EDI application, the deductions drawn indicate some of the challenges to be inadequate non IT staff training, lack of trust of other EDI partners, lack of flexibility, lack of maintainability and lack of awareness of benefits of EDI.
Exact and Approximate Solutions of the Perspective-Three-Point Problem

Model-based pose estimation techniques that match image and model triangles require large numbers of matching operations in real-world applications. The authors show that by using approximations to perspective, 2D lookup tables can be built for each of the triangles of the models. An approximation called 'weak perspective' has been applied previously to this problem; the authors consider two other perspective approximations: paraperspective and orthoperspective. These approximations produce lower errors for off-center image features than weak perspective. >
Effects of cell phone radiofrequency signal exposure on brain glucose metabolism.

CONTEXT The dramatic increase in use of cellular telephones has generated concern about possible negative effects of radiofrequency signals delivered to the brain. However, whether acute cell phone exposure affects the human brain is unclear. OBJECTIVE To evaluate if acute cell phone exposure affects brain glucose metabolism, a marker of brain activity. DESIGN, SETTING, AND PARTICIPANTS Randomized crossover study conducted between January 1 and December 31, 2009, at a single US laboratory among 47 healthy participants recruited from the community. Cell phones were placed on the left and right ears and positron emission tomography with ((18)F)fluorodeoxyglucose injection was used to measure brain glucose metabolism twice, once with the right cell phone activated (sound muted) for 50 minutes ("on" condition) and once with both cell phones deactivated ("off" condition). Statistical parametric mapping was used to compare metabolism between on and off conditions using paired t tests, and Pearson linear correlations were used to verify the association of metabolism and estimated amplitude of radiofrequency-modulated electromagnetic waves emitted by the cell phone. Clusters with at least 1000 voxels (volume >8 cm(3)) and P < . 05 (corrected for multiple comparisons) were considered significant. MAIN OUTCOME MEASURE Brain glucose metabolism computed as absolute metabolism (μmol/100 g per minute) and as normalized metabolism (region/whole brain). RESULTS Whole-brain metabolism did not differ between on and off conditions. In contrast, metabolism in the region closest to the antenna (orbitofrontal cortex and temporal pole) was significantly higher for on than off conditions (35.7 vs 33.3 μmol/100 g per minute; mean difference, 2.4 [95% confidence interval, 0.67-4.2]; P = .004). The increases were significantly correlated with the estimated electromagnetic field amplitudes both for absolute metabolism (R = 0.95, P < .001) and normalized metabolism (R = 0.89; P < .001). CONCLUSIONS In healthy participants and compared with no exposure, 50-minute cell phone exposure was associated with increased brain glucose metabolism in the region closest to the antenna. This finding is of unknown clinical significance.
Specific suppression of allograft rejection by soluble class I antigen and complexes with monoclonal antibody.

In this experiment, we investigated the effect of daily injection or continuous slow infusion of either DA (MHC haplotype, RT1a) serum or soluble DA class 1 MHC antigen or its complexes with monoclonal antibody on rejection of heterotopic heart allograft in the combination of PVG.RT1a (RT1a) donor into PVG (RT1c) recipient. DA serum delayed significantly both the early and late rejection of PVG.RT1a heart grafts in PVG recipients. Removal of soluble class I MHC antigen from DA serum by affinity chromatography on a monoclonal anti-class I antibody column completely abolished the immunosuppressive effect. Continuous infusion of purified soluble class I antigen from DA rat liver, even from day 4 after heart grafting, induced a significant prolongation of graft survival. This effectiveness was donor-specific and amplified by the mixture of monoclonal anti-class 1 (RT1a) antibody with DA serum--this being induced only by using continuous infusion but not by daily injection. The results indicate that soluble class I antigen can act as a specific immunosuppressive agent in allograft rejection and that its effect is amplified by monoclonal anti-class 1 antibody.
A New Method to Assess Perceived Well-Being among Elderly People – a Follow-Up Study

Abstract This is a follow-up study to a previous experiment that evaluated the feasibility of a simple monitoring device, Con-Dis, in assessing perceived well-being (PWB) among elderly people. Additionally, in the present study Con-Dis was used at the same time as blood pressure and heart rate monitors and pedometers to see the possible correlation between PWB, blood pressure, heart rate, and time spent on outdoor activity. The Con-Dis device proved technically functional, feasible, and informative throughout the four-week follow-up test period among elderly test subjects. In addition, PWB (measured by Con-Dis) appeared to correlate with mood, QoL, and time spent on outdoor activity.