Miracle-dz/UniFAR-FTUs huggingface dataset:
Effect of Winemaking on Phenolic Compounds and Antioxidant Activities of Msalais Wine

Msalais wine (MW) is a popular traditional wine with the cultural characteristics of a specific Chinese ethnic group. In this study, phenolic profiles and antioxidant characteristics were identified using chromatographic analysis. A total of thirty-eight compounds, including eight furans, eleven phenolic acids, fourteen flavonoids, and five others, were identified via LC-MS/QTOF. It was found that catechin is the most abundant phenolic compound in MW, followed by epicatechin, gallic acid, caffeic acid, rutin, and p-coumaric acid. Winemaking had a significant influence on the levels of phenols and antioxidant activity. Condensed juice (CJ) displayed the highest phenol and antioxidant activity levels, while the levels were significantly decreased during the fermentation process and gradually stabilized thereafter during the aging process. A correlation analysis between the polyphenols in Msalais and their antioxidant capacity was performed to determine which molecules contributed more to the antioxidant capacity in a complex mixture of polyphenols. All of the phenolic compounds, except ferulic acid, showed good correlation with DPPH, ABTS, and CUPRAC. Among them, resveratrol had the strongest antioxidant capacity, although its concentration was very low. Catechin also had a strong antioxidant capacity, which was positively correlated with its concentration. This indicates that the antioxidant activity of Msalais is related to the number, type, and structure of polyphenols.
Plasticity Improvement in a Co-Rich Co40Fe25Cr20Ni15 High-Entropy Alloy via Al Alloying

The mechanical properties of high-entropy alloys (HEAs) can be regulated by altering the stacking fault energy (SFE) through compositional modulation. The Co-rich HEAs, exhibiting deformation twinning and even strain-induced martensitic transformation at room temperature, suffer from insufficient ductility at high strength. In this work, we developed Co-rich (Co40Fe25Cr20Ni15)100−xAlx (x = 0 and 5 at.%) HEAs and investigated their tensile behaviors at room temperature. The addition of Al resulted in a massive improvement in the strength-ductility product, even at similar grain sizes, and also altered the fracture mode from quasi-cleavage to ductile dimple fracture. Interestingly, both alloys were deformed by mechanical twinning, which was also verified by molecular dynamics (MD) simulations. The MD simulations revealed the SFE increased upon Al addition; however, the slip energy barrier was reduced, which favored the mobility of dislocations and twinning propensity to prolong strain hardening. The present findings provide further insights into the regulation of mechanical properties of HEAs by Al-alloying.
Lecturer, Language Tutor, and Student Perspectives on the Ethics of the Proofreading of Student Writing

Various forms of proofreading of student writing take place in university contexts. Sometimes writers pay freelance proofreaders to edit their texts before submission for assessment; sometimes more informal arrangements take place, where friends, family, or coursemates proofread. Such arrangements raise ethical questions for universities formulating proofreading policies: in the interests of fairness, should proofreading be debarred entirely or should it be permitted in some form? Using questionnaires and semistructured interviews, this article investigates where three university stakeholder groups stand on the ethics of proofreading. Content lecturers, English language tutors, and students shared their views on the ethics of various lighter-touch and heavier-touch proofreader interventions. All three parties broadly approved of more minor interventions, such as correcting punctuation, amending word grammar, and improving sentence structure. However, students were found to be more relaxed than lecturers and language tutors about the ethics of more substantial interventions at the level of content. There were outliers within each of the three groups whose views on proofreading were wide apart, underscoring the difficulty of formulating proofreading policies that would attract consensus across the academy. The article concludes by discussing the formulation and dissemination of appropriate, research-led proofreading guidelines and issues for further exploration.
SSPP-Design Suppresses Horizontal Leaked Electrode Modes of Terahertz Photoconductive Antennas

Photoconductive antenna (PCA), which plays an essential role in a terahertz system, faces the challenge of low output power. The coplanar strip lines (CSLs) are fundamental components of a typical PCA. However, the horizontal leaked electrode modes, which are induced by the CSLs, directly impact the directivity of PCA and has not been resolved yet. Here, we propose a scheme that using spoof surface plasmon polariton (SSPP) to suppress the propagating horizontal electrode modes for enhancing directivity of PCA. For further improve the output performance of PCA, our microscale SSPP-design could combine with the well-realized nanoscale schemes which are based on enhancing the photoelectric conversion efficiency. Our design will be widely used in promising applications, such as THz detection, sensing and imaging.
Grid-Forming Control of Voltage Source Converters Based on the Virtual-Flux Orientation

The increasing penetration of renewable generation in power systems is causing growing concern about system stability. Grid-forming (GFM) control has been appointed as the technology required for achieving a high penetration of renewables in the grid, as it successfully contributes to the power system stability. This paper proposes a novel grid-forming control scheme for voltage source converters (VSC) achieving the operational characteristics of a virtual synchronous machine (VSM). The proposed scheme is based on the orientation of a defined virtual flux to a reference axis obtained from the emulation of the synchronous generator swing equation. The virtual flux is obtained by the integration of the VSC internal voltage and it is oriented to the reference axis by means of a flux controller that also controls the flux magnitude. In this way, the VSC synchronism is maintained, operating as a voltage source connected to the grid. Moreover, the flux orientation in turn allows to control the VSC active power, while the flux magnitude control allows to regulate the VSC reactive power or terminal voltage in isolated mode. The paper also demonstrates that the stability of GFM converters is negatively affected when emulating high inertia values. So, a stabilizer is also proposed for damping these modes. Finally, due to fact that GFM converters behave as voltage sources, their low voltage ride through capability becomes an issue, because they naturally respond to faults with high short-circuit currents, that cannot be withstand by power electronics converters. Therefore, a method for limiting fault currents is proposed as well in the paper. The proposed grid-forming control scheme has been implemented in a real-time control platform and validated using comprehensive simulation models in a real-time simulator for assessing its grid-forming capability.
Clinical Evaluation of Patients with Genetically Confirmed Familial Hypercholesterolemia

Familial hypercholesterolemia (FH) is the most common genetic disorder associated with premature atherosclerotic cardiovascular (CV) disease (ASCVD). However, it still is severely underdiagnosed. Initiating lipid-lowering therapy (LLT) in FH patients early in life can substantially reduce their ASCVD risk. As a result, identifying FH is of the utmost importance. The increasing availability of genetic testing may be useful in this regard. We aimed to evaluate the genetic profiles, clinical characteristics, and gender differences between the first consecutive patients referred for genetic testing with FH clinical suspicion in our institution (a Spanish cohort). Clinical information was reviewed, and all participants were sequenced for the main known genes related to FH: LDLR, APOB, PCSK9 (heterozygous FH), LDLRAP1 (autosomal recessive FH), and two other genes related to hyperlipidaemia (APOE and LIPA). The genetic yield was 32%. Their highest recorded LDLc levels were 294 ± 65 SD mg. However, most patients (79%) were under > 1 LLT medication, and their last mean LDLc levels were 135 ± 51 SD. LDLR c.2389+4A>G was one of the most frequent pathogenic/likely pathogenic variants and its carriers had significantly worse LDLc highest recorded levels (348 ± 61 SD vs. 282 ± 60 SD mg/dL, p = 0.002). Moreover, we identified an homozygous carrier of the pathogenic variant LDLRAP1 c.207delC (autosomal recessive FH). Both clinical and genetic hypercholesterolemia diagnosis was significantly established earlier in men than in women (25 years old ± 15 SD vs. 35 years old ± 19 SD, p = 0.02; and 43 ± 17 SD vs. 54 ± 19 SD, p = 0.02, respectively). Other important CV risk factors were found in 44% of the cohort. The prevalence of family history of premature ASCVD was high, whereas personal history was exceptional. Our finding reaffirms the importance of early detection of FH to initiate primary prevention strategies from a young age. Genetic testing can be very useful. As it enables familial cascade genetic testing, early prevention strategies can be extended to all available relatives at concealed high CV risk.
Geometry optimization of atomic microclusters using inverse‐power distance coordinates

Using redundant inverse‐power distance coordinates we present a series of optimizations on randomly generated argon clusters containing 12, 24, and 48 argon atoms. Our results clearly show that inverse distance coordinates perform significantly better for optimizing the geometries of atomic clusters than either Cartesian or natural/delocalized internal coordinates. The potential utility of these coordinates for global optimization is discussed.
Plastic optofluidic chip fabricated by femtosecond laser ablation

We have fabricated entirely by femtosecond micromachining a plastic optofluidic chip with integrated microfluidics and optical excitation/detection. First a microfluidic channel and two fiber grooves were ablated on one surface of the PMMA substrate. In order to collect and focus the fluorescence signal onto a detector, two binary Fresnel lenses were micromachined on the back surface of the substrate. The operatio of the integrated optofluidic chip was demonstrated by filling the channel with different Rhodamine 6G solution, and a limit of detection of 50 nM was achieved.
Simulation and Real-time Application of the Load Cell-based Segway

In this study, real-time application and simulation of the load cell-based Segway was carried out by using an STM32F103 microcontroller. The Brushless Direct Current Motor (BLDC) current and speed information was recorded on the SD card simultaneously during the real-time application of the vehicle. The BLDC parameters required for the simulation of the Segway were entered into the block diagram created in Matlab/Simulink interface. Then the load cell-based Segway was simulated. As a result of the simulation, the determined phase currents were compared with the real-time application results. In addition, the repetition test of the load cells was performed, and 99.9% correlation coefficients were obtained from the measurement of each load cell. As a result of this process, the measurement error rate of the load cells was determined as 0.01%. Finally, the currents of the BLDC motors were compared with the simulation study and the real-time application. The similarity of the currents with each other was obtained with an error rate of approximately 1.5–2%.
Artificial neural network based proportional plus integral plus derivative controller for a brushless DC position control system

Brushless DC (BLDC) motors are useful in applications such as process control, robotics, industrial automation, aerospace, electric vehicles etc. due to such advantages as the elimination of rotor losses and magnetizing current. Wider usage of BLDC motors demands optimum position control for high efficiency, accuracy and reliability. For an accurate position control, the estimation of moment of inertia and friction coefficient of the motor with load is essential. This paper incorporates the computation of the moment of inertia and friction coefficient of a BLDC motor with load at different load settings and emphasizes that load has an appreciable effect on the dynamic performance of the system. To obtain the optimum position control, a proportional plus integral plus derivative (PID) controller is employed and tuned using the PARR method. Artificial neural networks are used for computing the moment of inertia and friction coefficient of a BLDC motor with load and PID controller parameters at various load settings. Simulation results of the position control system are obtained at different load settings. From the results, it is evident that the PID controlled position control system responds to the desired position with minimum rise time, settling time and peak overshoot and is in dependent of load settings.
Soil Microbes from Saline–Alkali Farmland Can Form Carbonate Precipitates

The formation of soil inorganic carbon in saline–alkali lands is of great significance for enhancing soil carbon sequestration. As for the formation mechanisms, in addition to the discovered abiotic mechanisms, the microbial mechanisms remain unclear. To address this, soil microbes were isolated from the saline–alkali farmland of the Yellow River Delta in north China. Then, their capacity for carbonate precipitation formation was determined. Ten microbial strains were obtained from the soil. Of these, seven strains (four bacterial strains and three fungal strains), belonging to Rhodococcus sp. , Pseudomonas sp. , Bacillus sp. , Streptomyces sp. , Aspergillus sp. , Cladosporium sp. , and Trichoderma sp. , formed carbonate precipitates in the range of 89.77~383.37 mg. Moreover, the formation of carbonate precipitates was related to specific metabolisms by which microbes can raise the pH (from 7.20 to >8.00), suggesting that soil microbes that can enhance pH values by specific metabolisms containing the function of carbonate formation. Although an in situ experiment is needed to confirm such capacity, these results showed that soil bacteria and fungi existing in the saline–alkali farmland soil can form carbonate precipitates. The present study provided a microbial perspective for the mechanism of soil inorganic carbon formation, further implying a microbial potential of soil carbon sequestration in saline–alkali farmlands.
Mapping the astronomy content knowledge of Chilean in-service teachers

ABSTRACT This paper reports a mapping of the astronomy content knowledge held by a sample of 171 Chilean in-service teachers, both from primary and secondary education, using a multiple-choice test. The responses were analysed by total achievement, and the proportion of alternative conceptions for each item was identified. Moreover, the test items were divided by Big Ideas in Astronomy and curricular topics to analyse teachers’ performance by subject, and the effect of some demographic factors was calculated. The results show a relatively low level of astronomy content knowledge and a considerable presence of alternative conceptions amongst Chilean in-service teachers, especially in day-to-day topics like diurnal motion, seasons, and Moon phases. Furthermore, we detected a significant effect on secondary teachers’ performance depending on their teaching degree and on primary teachers’ performance concerning their gender and previous participation in astronomy professional development programmes. Our outcomes offer evidence to improve astronomy teacher training, especially in the Chilean context, and contribute to the still scarce astronomy education research from the country.
COMT but Not 5HTTLPR Gene Is Associated with Depression in First-Episode Psychosis: The Role of Stressful Life Events

Serotonergic and dopaminergic systems are involved in the regulation of mood and reactivity to psychological stress. This study explores, in a sample of first episode psychosis (FEP) patients, whether more severe depressive symptoms were found in those who: (1) experienced a major stressful event in the 6 months preceding illness onset; and (2) were homozygous for the COMT Val158 allele or carrying the S allele of 5-HTTLPR. A total of 186 FEP patients recruited were assessed using the Hamilton Rating Scale for Depression (HAMD) for depressive symptoms. Stressful life events (SLEs) were collected by the List of Events Scale. The genotypes of 5-HTTLPR, rs25531, and COMT Val158 Met were performed. It has been found that higher levels of depression is associated with the presence of SLEs (p = 0.019) and with COMT Val158 allele homozygosity (p = 0.029), but not with carrying the S allele of 5-HTTLPR. The COMT gene moderates the association between depression and SLEs as Val158 allele homozygote patients experiencing SLEs had the highest level of depressive symptoms compared to the others (p = 0.002). The present study provides initial evidence for an effect of the COMT Val158 homozygosity and severe stressful life events on the severity of depressive symptoms in first episode psychosis.
The Ability of ZnFe2O4 Nanostructure as Electromagnetic Wave Absorber in Frequency Range 2-18 GHz

ZnFe2O4 nanomaterials were prepared using a solid-state reaction method using high energy milling (750 rpm) for 30 hours and calcined at 1000°C for 5 hours. The characterizations used include XRD, SEM, VSM, and VNA. The measurement results show that the sample has a single phase with a cubic structure. The surface morphology of heterogeneous samples with a particle size of 250-400 nm shows magnetic performance with Ms 2.38 emu/g and Hc 11.29 kOe. The sample also can absorb electromagnetic waves in the frequency range of 2-18 GHz with a minimum RL value of ~-18.79 dB at a frequency of 3.66 GHz, while RL ~-13.32 dB has a bandwidth of 0.9 GHz.
Saturated Kochen–Specker-type configuration of 120 projective lines in eight-dimensional space and its group of symmetry

There exists an example of a set of 40 projective lines in eight-dimensional Hilbert space producing a Kochen–Specker-type contradiction. This set corresponds to a known no-hidden variables argument due to Mermin. In the present paper it is proved that this set admits a finite saturation, i.e., an extension up to a finite set with the following property: every subset of pairwise orthogonal projective lines has a completion, i.e., is contained in at least one subset of eight pairwise orthogonal projective lines. An explicit description of such an extension consisting of 120 projective lines is given. The idea to saturate the set of projective lines related to Mermin’s example together with the possibility to have a finite saturation allow to find the corresponding group of symmetry. This group is described explicitely and is shown to be generated by reflections. The natural action of the mentioned group on the set of all subsets of pairwise orthogonal projective lines of the mentioned extension is investig.
Cumulative UV Exposure or a Modified SCINEXA™-Skin Aging Score Do Not Play a Substantial Role in Predicting the Risk of Developing Keratinocyte Cancers after Solid Organ Transplantation—A Case Control Study

Simple Summary Due to life-long immunosuppression, organ transplant recipients are prone to skin cancer development. We evaluated the association of cumulative UV burden with skin aging and skin cancer in two groups of transplant patients with and without skin cancer, who were matched for gender, age, type of organ transplanted, post-transplantation period, and immunosuppressive therapy. Individuals with actinic keratoses had a 7.5-fold risk for skin cancer development, and those with green or blue eyes a 4.1- or 3.6-fold risk, respectively; carriers of particular MC1R genotypes associated with a diminished function had a 1.9-fold increased risk. The extent of skin aging was only connected with a higher number of tumors, but not with the development of skin cancer per se. Abstract The risk of keratinocyte cancer is determined by intrinsic and extrinsic factors, which also influence skin aging. Few studies have linked skin aging and UV exposure with the incidence of non-melanoma skin cancer (NMSC). We evaluated signs of actinic skin damage and aging, individual UV burden, and melanocortin-1 receptor (MC1R) variants. A total of 194 organ transplant recipients (OTR) who suffered from NMSC were compared to 194 tumor-free controls matched for gender, age, type of transplanted organ, post-transplantation (TX) period, and immunosuppressive therapy. Compared with the cases, the controls scored higher in all skin aging scores and there were no differences in UV burden except for intentional whole-body UV exposure for specific UV scenarios and periods of life in favor of cases. The number of NMSCs correlated with all types of skin aging scores, the extent of intentional sun exposure, older age, longer post-TX period, shorter interval from TX to first NMSC, and specific MC1R risk groups. Multivariable models revealed a 7.5-fold risk of developing NMSC in individuals with actinic keratosis; 4.1- or 3.6-fold in those with green or blue eyes, respectively; and a 1.9-fold increased risk in the MC1R medium- + high-risk group. In the absence of skin aging contributing to NMSC development, certain MC1R risk types may identify OTR at risk for high tumor burden.
A medical Q&A system with entity linking and intent recognition

As a result of current dearth of medical physicians and medical resources in some countries, and also due to the growth of the Internet, an increasing number of people are holding medical question-and-answer sessions online. The goal of this research is to create a medical question-answering system based on a knowledge graph that will allow individuals to acquire answers to medical queries rapidly on the computer. To accomplish it, we propose a new mechanism of intent recognition and entity linking on a medical knowledge graph. After these processes, the system uses Cypher language to search the knowledge graph for the answer based on the extracted query-intent and entity, using the specified rule template that was formed during slot filling. Two models are used in this study to fulfill the tasks of intent recognition and named entity recognition, and the system also enhanced the model's results with information from the knowledge graph using the template matching method. Additionally, the entity linking procedure has been finished in order to better integrate models into a question-and-answer system. The entity linking function can link non-standard words in user questions to common disease names on the knowledge graph, to better obtain answers from the knowledge graph. The intent recognition used the BERT-TextCNN model, and the accuracy obtained on the CMID public dataset was 0.67. The named entity recognition used the BiLSTM-CRF model, and the accuracy obtained on the cMedQANER public dataset was 0.96. The entity linking process used the ESIM model, and the accuracy obtained on the Yidu-N7K public dataset was 0.96. The system used the above trained models and template matching methods to answer a total of 13 types of questions: ‘Definition’, ‘Cause’, ‘Prevention’, ‘Disease manifestations’, ‘Associated conditions’, ‘Treatment’, ‘Department’, ‘Infectious’, ‘Cure rate’, ‘Taboo’, ‘Physical Examination Program’, ‘Treatment time’ and ‘Food recommend’. To compare the effectiveness of this system with the system that only uses the template matching method, the experiment was designed with 200 questions divided into four groups. ‘whether the question uses the standard entity names in the knowledge graph’ and ‘whether the question uses the feature words in the intent template’ were controlled separately in different groups. The experimental results demonstrate that the correct answer rate of this system is much higher than that of the system based on template matching only when users enter questions without using standard entity names from the knowledge graph or without using feature words from the intent template.