Miracle-dz/UniFAR-FTUs huggingface dataset:
Sexuelle Identität, der Konsum von Alkohol und anderen Drogen, gesundheitliche Probleme und Behandlungsansätze: Ein unsystematischer Forschungsüberblick

Zusammenfassung Hintergrund Die Zahlen von Menschen, die ihre sexuelle Identität nicht als heterosexuell sondern als schwul, lesbisch, bisexuell oder in einer anderen Kategorie definieren, steigen seit Jahren leicht an; man schätzt, dass in westlichen Ländern ca. 5% der Bevölkerung zu den sexuellen Minderheiten zu rechnen sind. Diese Studie ist darauf angelegt, die psychischen Problemlagen der sexuellen Minoritäten anhand US-amerikanischer Bevölkerungsstudien sowie weiterer wichtiger Studien aus anderen Ländern genauer darzustellen. Ergebnisse Zusammenfassend ergibt sich Folgendes: Unabhängig vom Geschlecht liegt der Konsum von Alkohol und anderen Drogen sowie die Abhängigkeit von diesen Stoffen mindestens auf dem Niveau der heterosexuellen Männer. Lesbisch/schwule und bisexuelle Frauen sind noch etwas stärker durch den Konsum von psychoaktiven Substanzen belastet als schwule und bisexuelle Männer. Untersucht man Belastungen durch Depressionen und Suizidversuche, findet man wiederum bei den sexuellen Minoritäten höhere Belastungen. LSB-Frauen haben die höchsten Raten hinsichtlich Depressionen und Ängsten. Darüber hinaus weisen die Daten darauf hin, dass bisexuelle Männer und Frauen hohe psychische Belastungen haben. Alles in allem genommen ist davon auszugehen, dass die sexuellen Minoritäten einen relativ hohen Bedarf an Behandlungen ihrer psychischen Störungen haben. Dennoch gibt es bislang nur sehr wenige Behandlungsprogramme mit der Zielgruppe: sexuelle Minoritäten. Schlussfolgerungen Wir benötigen dringend deutsche Studien zu sexuellen Minoritäten allgemein und besonders zu trans* Personen mit ihren sehr spezifischen Problemlagen. Die Studien sollten neben den Substanzkonsumstörungen der sexuellen Minoritäten auch andere psychische Störungen erfassen. Kenntnisse über die psychische Befindlichkeit sexueller Minoritäten sind die Grundlage für optimale Behandlungsgestaltungen.
5 th International Workshop on Linguistically Interpreted Corpora The 20 th International Conference on Computational Linguistics — Proceedings —

In this paper we describe the construction of a new Japanese lexical resource: the Hinoki treebank. The treebank is built from dictionary definition sentences, and uses an HPSG based Japanese grammar to encode the syntactic and semantic information. We show how this treebank can be used to extract thesaurus information from definition sentences in a language-neutral way using minimal recursion se-
Multiple Pathways Are Co-regulated by the Protein Kinase Snf1 and the Transcription Factors Adr1 and Cat8*

ADR1 and CAT8 encode carbon source-responsive transcriptional regulators that cooperatively control expression of genes involved in ethanol utilization. These transcription factors are active only after the diauxic transition, when glucose is depleted and energy-generating metabolism has shifted to the aerobic oxidation of non-fermentable carbon sources. The Snf1 protein kinase complex is required for activation of their downstream target genes described previously. Using DNA microarrays, we determined the extent to which these three factors collaborate in regulating the expression of the yeast genome after glucose depletion. The expression of 108 genes is significantly decreased in the absence of ADR1. The importance of ADR1 during the diauxic transition is illustrated by the observation that expression of almost one-half of the 40 most highly glucose-repressed genes is ADR1-dependent. ADR1-dependent genes fall into a variety of functional classes with carbon metabolism containing the largest number of members. Most of the genes in this class are involved in the oxidation of different non-fermentable carbon sources. These microarray data show that ADR1 coordinates the biochemical pathways that generate acetyl-CoA and NADH from non-fermentable substrates. Only a small number of ADR1-dependent genes are also CAT8-dependent. However, nearly one-half of the ADR1-dependent genes are also dependent on the Snf1 protein kinase for derepression. Many more genes are SNF1-dependent than are either ADR1- or CAT8-dependent suggesting that SNF1 plays a broader role in gene expression than either ADR1 or CAT8. The largest class of SNF1-dependent genes encodes regulatory proteins that could extend SNF1 dependence to additional pathways.
The Effect of 8-Week Nordic Hamstring Exercise on Hamstring Quadriceps Ratio and Hamstring Muscle Strength

The aim of the study is to investigate the effect of 8-week Nordic Hamstring (NH) exercise on hamstring/quadricepsratio (H/Q) and hamstring muscle strength. 22 amateur soccer players participated in the study. Soccer players weredivided into two groups: the control group (CG) (n = 11) who only practiced soccer training and the NordicHamstring exercise group (NHEG) (n = 11) who performed NH in addition to soccer training. The isokinetic kneemuscle strength of the soccer player was measured twice at the beginning of the study and after the 8 week NHexercise. An isokinetic dynamometer was used to determine isokinetic knee strengths of soccer players. Thedifference between pre-test and post-test results of isokinetic knee muscle strength of soccer players was determinedby Wilcoxon test. According to the results obtained, it was found that the H/Q ratio (at 180ºs-1 and 240ºs-1 angularvelocities) and hamstring muscle strength (60ºs-1, 180ºs-1 and 240ºs-1 angular velocities) increased statisticallysignificantly (p<0.05). As a result, it can be stated that NH exercise is a very important factor in achieving thedesired level of H/Q ratio, which is an important factor in increasing sportive performance and thus decreasing therisk of injury as well as increasing hamstring muscle strength.
Minimum Time Search in Uncertain Dynamic Domains with Complex Sensorial Platforms

The minimum time search in uncertain domains is a searching task, which appears in real world problems such as natural disasters and sea rescue operations, where a target has to be found, as soon as possible, by a set of sensor-equipped searchers. The automation of this task, where the time to detect the target is critical, can be achieved by new probabilistic techniques that directly minimize the Expected Time (ET) to detect a dynamic target using the observation probability models and actual observations collected by the sensors on board the searchers. The selected technique, described in algorithmic form in this paper for completeness, has only been previously partially tested with an ideal binary detection model, in spite of being designed to deal with complex non-linear/non-differential sensorial models. This paper covers the gap, testing its performance and applicability over different searching tasks with searchers equipped with different complex sensors. The sensorial models under test vary from stepped detection probabilities to continuous/discontinuous differentiable/non-differentiable detection probabilities dependent on distance, orientation, and structured maps. The analysis of the simulated results of several static and dynamic scenarios performed in this paper validates the applicability of the technique with different types of sensor models.
The Grain of Domains: The Evolutionary-Psychological Case Against Domain-General Cognition

: Prominent evolutionary psychologists have argued that our innate psychological endowment consists of numerous domain-specific cognitive resources, rather than a few domain-general ones. In the light of some conceptual clarification, we examine the central in-principle arguments that evolutionary psychologists mount against domain-general cognition. We conclude (a) that the fundamental logic of Darwinism, as advanced within evolutionary psychology, does not entail that the innate mind consists exclusively, or even massively, of domain-specific features, and (b) that a mixed innate cognitive economy of domain-specific and domain-general resources remains a genuine conceptual possibility. However, an examination of evolutionary psychology's ‘grain problem’ reveals that there is no way of establishing a principled and robust distinction between domain-specific and domain-general features. Nevertheless, we show that evolutionary psychologists can and do live with this grain problem without their whole enterprise being undermined.
Latent membrane protein 1 of Epstein–Barr virus interacts with JAK3 and activates STAT proteins

Latent membrane protein 1 (LMP1) acts like a permanently activated receptor of the tumor necrosis factor (TNF)‐receptor superfamily and is absolutely required for B cell immortalization by Epstein–Barr virus. Molecular and biochemical approaches demonstrated that LMP1 usurps cellular signaling pathways resulting in the induction of NF‐κB and AP‐1 via two C‐terminal activating regions. We demonstrate here that a third region encompassing a proline rich sequence within the 33 bp repetitive stretch of LMP1's C‐terminus is required for the activation of Janus kinase 3 (JAK3). The interaction of LMP1 and JAK3 leads to the enhanced tyrosine auto/transphosphorylation of JAK3 within minutes after crosslinking of a conditional NGF‐R:LMP1 chimera and is a prerequisite for the activation of STAT transcription factors. These results reveal a novel activating region in the LMP1 C‐terminus and identify the JAK/STAT pathway as a target of this viral integral membrane protein in B cells.
Method of overlapping patches for electromagnetic computation near imperfectly conducting cusps and edges

An asymptotic solution method for three-dimensional electromagnetic field problem inside and outside an imperfectly conducting cusp is proposed. Implementation of the method leads to a boundary value problem with singular boundary conditions. This problem can be solved numerically using the partition of unity method. Wave propagation in an L-shaped waveguide is modeled as an example.
Ranut: A Labeled Transition System-Based Model for Trust Management

Trusted computing aims to bring the concept of trust from society to cyberspace, which makes the studies of trust management in trusted computing an exigent demand. In this paper, we propose a LTS-based model -- Ranut. First of all, the four building blocks of the model, such as information collection, trust estimation, trust library and trust application, have been introduced, Second, the formal definitions of identity based trust and action based trust are presented, followed which are the three rules for state transition under single action. And finally, based on TCG specification and access control mechanism, the implementation method of the model has been discussed in detail.
Pentaquark baryons in string theory

The recently observed pentaquark baryons Θ + and Ξ -- are studied in the dual gravity theory of QCD. By developing a general formulation useful for studying the branched string web in a curved space, simple mass formulae of the pentaquark baryons are derived in the Maldacena prototype model for supersymmetric QCD and a more realistic model for ordinary QCD. Even though the approximations adopted here in deriving these formulae are extremely naive, the predicted values of the masses do not differ significantly from their experimental values. We thus conclude that this approach is promising for the purpose of obtaining a description of the observed masses of pentaquarks and of their extremely narrow decay widths. With the aim of constructing more reliable mass formulae, a preliminary sketch is given of how spin, the hyperfine interaction and parity are considered in the string picture.
The Value of Experience: Psychedelics, phenomenology and contemporary perspectives on drug use

The use of psychedelic substances has become an emerging trend during the last decade. Perhaps this is due to the substances effects, inducing processes of autognosis (meaning selfknowledge by the process of self-analysis). To better understand this phenomenon, fieldwork was conducted among groups and individuals in Oslo who use psychedelic substances with various introspective intentions. The thesis addresses individuals’ experiences and the sociality in between, situated in a wider cultural context by asking: What is the value of experience? How do these actors conceptualize, articulate and structure their psychedelic experiences? How might these personal experiences affect their social world, and in turn, how do the social context affect their psychedelic practice? Drawing on the analysis of ethnographic data, inspired by phenomenological theory, I argue the value of the psychedelic experience is the emotional, sensorial and affective experience of the psychedelic space, which stimulates new insights and novel perspectives (a ‘radical experience’). New perspectives subsequently lead to a change in habitual orientation. Other bodily practices, such as yoga and floatation, are recognized and practiced due to similar functions. Sociality around these substances is structured on the basis of individual intentions and preferences in outcome, as mindset and contextual environment (‘set and setting’) are variables that interact with the experience itself. The seemingly ineffable character of these experiences means that sharing them by the way of narrative, both in person and through other psychedelic mediums, help participants conceptualize and integrate these experiences into their existing cultural framework. These other mediums of translating the psychedelic experience, such as podcast and visionary art, become collectivization of knowledge on a larger scale. The sharing of experiences, communal knowledge and the contextual circumstance of illegality, create exclusive psychedelic communities. On the basis of these arguments, I suggest that in order to understand these communities and their behavior, there is great scientific value in interpreting this social phenomenon from the perspective of the psychedelic experience itself by utilizing phenomenological theory and methods.
On the Practical Secret Sharing Scheme

In this paper, we attempt to construct practical secret sharing schemes, which scheme has smaller share size and can detect cheating with high probability. We de ne two secure ramp schemes, secure ramp scheme and strongly secure ramp scheme. Then, we propose two constructions of secure ramp scheme. These schemes both have small share size and the cheating can be detected with high probability. So, they are practical secret sharing schemes. key words: secret sharing scheme, ramp scheme, cheating of participant, share size
A RULE-BASED EXPERT SYSTEM FOR AUTOMATED ECG DIAGNOSIS

This paper presents the development of a rule-based expert system that emulates the ECG interpretation skills of an expert cardiologist for introducing way of automating the diagnosis of cardiac disorders. The knowledge of an expert is confined to him and is not freely available for decision-making. An expert system is developed to overcome this problem. In this rule-based expert system, patient’s heart rate and the wave characteristics of the ECG are considered. With these ‘facts’, rules are framed and a rule base is developed in consultation with experts. An inference engine in the expert system uses these inputs and the rule base to identify any abnormality in the patient’s heart . An expert system designed on the basis of information derived from the analysis of (ECG) using Microsoft Visual studio.Net. For this paper the shape of ECG is used to diagnose ECG beat in four types such as Normal beats (N), Sinus Bradycardia beat, Sinus Tachycardia beat and Sinus Arrhythmia beat. The ECG image from ECG simulator is processed by some image processing techniques such as red grid removing, noise rejection, and image thinning firstly, then, combining detection component of ECG signal(P,QRS,T) based on Time-series ECG are obtained. In addition, other features of the signal are obtained to be used as final features for diagnosis.
Investigation of Mcp1 as a Quantitative Trait Gene for Prion Disease Incubation Time in Mouse

The genetic basis of prion disease incubation time is principally determined by polymorphisms in the prion protein gene, Prnp. However, it is now known that other genetic factors are important. Several quantitative trait loci (QTL) have been identified across the genome including a broad region of linkage on Mmu11. Monocyte chemoattractant protein 1 (MCP-1) maps to this region and has been associated with microglial activation and reduced survival in the ME7 mouse scrapie model of prion disease. We have identified 10 polymorphisms, 3 of which are nonsynonomous, in Mcp1 between “long” (CAST) and “short” (SJL or NZW) incubation-time mouse strains. Crosses between these strains and Mcp1−/− mice inoculated with the Chandler/RML mouse scrapie prion strain formed the basis of a quantitative complementation test. In these models loss of Mcp1 did not show an increase in incubation time suggesting that the effects of Mcp1 may be specific to the ME7 prion strain and that Mcp1 does not contribute to the QTL described on Mmu11.
Advances in InP HEMT WR1.5 Amplifier MMICs

We show on-wafer measured data for four amplifier designs targeting the WR1.5 band. One design shows gain exceeding 20 dB over the entire WR1.5 bandwidth. We show the maturation of the InP HEMT process, and show that now fewer gain stages are necessary to achieve comparable gain numbers reported in past publications. We also show that gain is achievable with larger device peripheries. These larger periphery devices should ultimately allow for greater saturated output power levels, though this is not confirmed at the time of this writing.
Approximation Algorithms for a Minimization Variant of the Order-Preserving Submatrices and for Biclustering Problems

Finding a largest Order-Preserving SubMatrix, OPSM, is an important problem arising in the discovery of patterns in gene expression. Ben-Dor et al. formulated the problem in Ben-Dor et al. [2003]. They further showed that the problem is NP-complete and provided a greedy heuristic for the problem. The complement of the OPSM problem, called MinOPSM, is to delete the least number of entries in the matrix so that the remaining submatrix is order preserving. We devise a 5-approximation algorithm for the MinOPSM based on a formulation of the problem as a quadratic, nonseparable set cover problem. An alternative formulation combined with a primal-dual algorithm improves the approximation factor to 3. The complexity of both algorithms for a matrix of size m × n is O(m2n). We further comment on the related biclustering problem.
Disparity-Tuned Population Responses from Human Visual Cortex

We used source imaging of visual evoked potentials to measure neural population responses over a wide range of horizontal disparities (0.5–64 arcmin). The stimulus was a central disk that moved back and forth across the fixation plane at 2 Hz, surrounded either by binocularly uncorrelated dots (disparity noise) or by correlated dots presented in the fixation plane. Both disk and surround were composed of dynamic random dots to remove coherent monocular information. Disparity tuning was measured in five visual regions of interest (ROIs) [V1, human middle temporal area (hMT+), V4, lateral occipital complex (LOC), and V3A], defined in separate functional magnetic resonance imaging scans. The disparity tuning functions peaked between 2 and 16 arcmin for both types of surround in each ROI. Disparity tuning in the V1 ROI was unaffected by the type of surround, but surround correlation altered both the amplitude and phase of the disparity responses in the other ROIs. Response amplitude increased when the disk was in front of the surround in the V3A and LOC ROIs, indicating that these areas encode figure–ground relationships and object convexity. The correlated surround produced a consistent phase lag at the second harmonic in the hMT+ and V4 ROIs without a change in amplitude, while in the V3A ROI, both phase and amplitude effects were observed. Sensitivity to disparity context is thus widespread in visual cortex, but the dynamics of these contextual interactions differ across regions.
Determinação da carga fisiológica imposta no jogador de futebol infantil e indicadores técnicos de treino

xv INTRODUÇÃO GERAL . 1 REFERÊNCIAS. 5 OBJETIVOS . 9 OBJETIVO GERAL . 9 OBJETIVOS ESPECÍFICOS . 9 ARTIGO 1: EXERCISE INTENSITY DURING COMPETITIVE MATCH PLAY AND TRAINING MONITORED BY THE HEART RATE IN SOCCER PLAYERS. 11 ACKNOWLEDGMENTS. 12 ABSTRACT. 13. 13 INTRODUCTION. 14 HISTORICAL ASPECTS OF THE USE OF HEART RATE. 17 ANALYSIS OF THE ABSOLUTE VALUES OF HEART RATE. 19 EXERCISE INTENSITY THROUGH THE HR-VO2 RELATION. 21 EXERCISE INTENSITY THROUGH THE HR AND METABOLIC THRESHOLDS RELATION. 23 EXERCISE INTENSITY THROUGH THE MAXIMUM HEART RATE PERCENTAGE. 24 EXERCISE INTENSITY IN THE FIRST AND SECOND HALF OF THE GAME. 26 EXERCISE INTENSITY PER PLAY POSITION. 29 USE OF HEART RATE IN SPECIFIC SOCCER TRAINING. 31 LIMITING FACTORS OF THE HEART RATE USE. 33 CONCLUSION. 36
Linear model-based testing of ADC nonlinearities

In this brief, we demonstrate the procedures of linear model-based testing for the example of a 12-b Nyquist-rate analog-to-digital converter (ADC). In a production test environment, we apply this technique to two wafer lots of devices, and we establish that the model is robust with respect to its ability to reduce the uncertainty of the test outcome. Reducing this uncertainty is particularly beneficial for higher resolution devices, for which measurement noise increasingly corrupts the measured "signal" that is the nonlinearity of the device under test.
Chromosome Structuring Limits Genome Plasticity in Escherichia coli

Chromosome organizations of related bacterial genera are well conserved despite a very long divergence period. We have assessed the forces limiting bacterial genome plasticity in Escherichia coli by measuring the respective effect of altering different parameters, including DNA replication, compositional skew of replichores, coordination of gene expression with DNA replication, replication-associated gene dosage, and chromosome organization into macrodomains. Chromosomes were rearranged by large inversions. Changes in the compositional skew of replichores, in the coordination of gene expression with DNA replication or in the replication-associated gene dosage have only a moderate effect on cell physiology because large rearrangements inverting the orientation of several hundred genes inside a replichore are only slightly detrimental. By contrast, changing the balance between the two replication arms has a more drastic effect, and the recombinational rescue of replication forks is required for cell viability when one of the chromosome arms is less than half than the other one. Macrodomain organization also appears to be a major factor restricting chromosome plasticity, and two types of inverted configurations severely affect the cell cycle. First, the disruption of the Ter macrodomain with replication forks merging far from the normal replichore junction provoked chromosome segregation defects. The second major problematic configurations resulted from inversions between Ori and Right macrodomains, which perturb nucleoid distribution and early steps of cytokinesis. Consequences for the control of the bacterial cell cycle and for the evolution of bacterial chromosome configuration are discussed.