Miracle-dz/UniFAR-FTUs huggingface dataset:
A receiver for WCDMA/EDGE mobile phones with inductorless front-end in 65nm CMOS

The spectrum allocated for the operation of cellular services is country dependent and fragmented in several frequency bands [1]. Mobile phones, to be usable globally, are therefore required to support many bands. The lack of suitable tuneable pre-selection filters and duplexers mandates the use of a large number of low-noise amplifiers (LNAs) in the receiver section of the transceiver. Minimization of the area occupied by the LNAs is therefore important. Virtually every transceiver for mobile phone applications published to date makes use of LNAs employing on-chip [3,5] or on-passivation [4] spiral inductors. Spiral inductors are large and do not scale with technology, leading to an increasing relative cost of the receiver front-end with newer technology nodes. Post-passivation and SiP technologies also add noticeably to the costs. In this paper we present the first receiver employing no on-chip or above-passivation spiral inductors on the receive signal path and with a linearity and noise performance suitable for WCDMA/EDGE applications. The eight channel direct-conversion receiver is part of a multimode transceiver requiring neither RX nor TX interstage SAW filters for FDD 3G operation. A block diagram of the receiver is shown in Fig. 21.4. 1.
Potential of Olfactory Ensheathing Cells from Different Sources for Spinal Cord Repair

Spinal cord injury (SCI) induces a permanent disability in patients. To this day no curative treatment can be proposed to restore lost functions. Therefore, extensive experimental studies have been conducted to induce recovery after SCI. One of the most promising therapies is based on the use of olfactory ensheathing cells (OECs). OECs can be obtained from either the olfactory bulbs (OB-OECs) or from olfactory mucosa (OM-OECs), involving a less invasive approach for autotransplantation. However the vast majority of experimental transplantations have been focusing on OB-OECs although the OM represents a more accessible source of OECs. Importantly, the ability of OM-OECs in comparison to OB-OECs to induce spinal cord recovery in the same lesion paradigm has never been described. We here present data using a multiparametric approach, based on electrophysiological, behavioral, histological and magnetic resonance imaging experiments on the repair potential of OB-OECs and OM-OECs from either primary or purified cultures after a severe model of SCI. Our data demonstrate that transplantation of OECs obtained from OB or OM induces electrophysiological and functional recovery, reduces astrocyte reactivity and glial scar formation and improves axonal regrowth. We also show that the purification step is essential for OM-OECs while not required for OB-OECs. Altogether, our study strongly indicates that transplantation of OECs from OM represents the best benefit/risk ratio according to the safety of access of OM and the results induced by transplantations of OM-OECs. Indeed, purified OM-OECs in addition to induce recovery can integrate and survive up to 60 days into the spinal cord. Therefore, our results provide strong support for these cells as a viable therapy for SCI.
dentification of lipids an lipid-binding proteins in phloem exudates from Arabidops s thalia a

In mammals, cadmium is widely considered as a non-genotoxic carcinogen acting through a methylation-dependent epigenetic mechanism. Here, the effects of Cd treatment on the DNA methylation patten are examined together with its effect on chromatin reconfiguration in Posidonia oceanica. DNA methylation level and pattern were analysed in actively growing organs, under short(6 h) and long(2 d or 4 d) term and low (10 mM) and high (50 mM) doses of Cd, through a Methylation-Sensitive Amplification Polymorphism technique and an immunocytological approach, respectively. The expression of one member of the CHROMOMETHYLASE (CMT) family, a DNA methyltransferase, was also assessed by qRT-PCR. Nuclear chromatin ultrastructure was investigated by transmission electron microscopy. Cd treatment induced a DNA hypermethylation, as well as an up-regulation of CMT, indicating that de novo methylation did indeed occur. Moreover, a high dose of Cd led to a progressive heterochromatinization of interphase nuclei and apoptotic figures were also observed after long-term treatment. The data demonstrate that Cd perturbs the DNA methylation status through the involvement of a specific methyltransferase. Such changes are linked to nuclear chromatin reconfiguration likely to establish a new balance of expressed/repressed chromatin. Overall, the data show an epigenetic basis to the mechanism underlying Cd toxicity in plants.
Tinea of vellus hair: an indication for systemic antifungal therapy

Background Topical antifungal treatment is indicated in tinea of glabrous skin, except in cases of extensive, multiple or recurrent lesions, or immunocompromised patients. However, in daily practice there are cases resistant to topical treatment despite these indications. Parasitism of the hair could be the cause behind the majority of isolated lesions of ringworm of hairless skin with a poor outcome with topical antifungal treatment.
Generalized State Scaling and Applications to Feedback, Feedforward, and Nontriangular Nonlinear Systems

We propose a global high-gain scaling-based state-feedback controller for a general class of nonlinear systems containing uncertain functions of all the states and the control input as long as polynomial bounds on ratios of some uncertain system terms are available. The design is based on a high gain scaling involving appropriate powers of a high gain scaling parameter which is a dynamic signal driven by the state. The design is applicable to both lower triangular (strict-feedback) and upper triangular (feedforward) systems, and also to nontriangular systems as long as a set of linear inequalities involving powers of the polynomial bounds on the ratios of uncertain system terms and scaling orders is solvable. The stability analysis is based on our recent results on uniform solvability of coupled state-dependent Lyapunov inequalities
Teachers' learning styles : their effect on teaching styles

concrete and sequential/random--to characterize four types of "transaction ability channels": Concrete Sequential, Abstract Sequential, Abstract Random, and Concrete Random, each of which has particular behaviour and characteristics. These have been measured on an instrument called, the Style Delineator (1982) and compared to an analysis of overt behavior (Gregorc, 1979). In the Concrete Sequential style, the individual's approach to learning is orderly, organized, thorough and precise. The working style is direct, structured, predictable, and perfection-oriented. Preference is shown for the concrete, physically based, and the practical. The individual is task-oriented, industrious, factual, and exact. Other characteristics include steadfastness, reliability, and self-confidence.
Father group leaders' experiences of creating an arena for father support – A qualitative study

BACKGROUND Parental classes consisting of only fathers, hereafter referred to as father groups, have existed in Sweden since the mid-1990s. OBJECTIVE To describe the father group leaders' perspectives on and experiences of father groups. METHOD A qualitative study was conducted using content analysis. Eleven individual interviews with father group leaders were conducted. An interview guide was used. SETTINGS AND PARTICIPANTS The study was set in different parts of Sweden. The participants were eleven men who are father group leaders. They were recruited using the snowball method. FINDINGS The father group leaders described how participants often have high education levels and orderly social circumstances. The leaders described that the groups increased the fathers' reflection about parenthood, which could benefit the whole family in both the short and long term. The father group leaders reported that some of the topics in the sessions directly influenced fathers to discuss issues regarding equality and their co-parenting relationship. They also argued that participating in father groups might help convince fathers to take more parental leave and build stronger relationships with their partner and child.
Low-profile Ku-band array antenna for broadband mobile satellite communications

This paper presents the design of a planar array antenna for Ku-band mobile satellite communications systems. 12The antenna is low-profile and is designed for integration in small aircrafts and ground vehicles. The antenna allows simultaneous transmit and receive operations taking advantage of the complete available aperture surface for both transmit and receive functions. The beam steering is electronic for the elevation and polarisation angles and mechanical for the azimuth scan. The paper presents the main characteristics of the antenna architecture and the design of the radiating aperture with emphasis on isolation between transmit and receive channels. A first sub-array module of the antenna has been realized and measured. The results of network parameters and radiation patterns are presented.
Design of H∞ bounded non-fragile controllers for discrete-time systems

This paper deals with the quadratic stabilization of discrete-time LTI systems using state-feedback controllers with bounded coefficients. The controllers are guaranteed to be non-fragile with respect to additive or multiplicative implementation errors. The approach is based on robust-control tools and LMIs. Finally, an example is given in order to illustrate the effectiveness of the approach.
Loss of MMP-2 disrupts skeletal and craniofacial development and results in decreased bone mineralization, joint erosion and defects in osteoblast and osteoclast growth.

The 'vanishing bone' or inherited osteolysis/arthritis syndromes represent a heterogeneous group of skeletal disorders characterized by mineralization defects of affected bones and joints. Differing in anatomical distribution, severity and associated syndromic features, gene identification in each 'vanishing bone' disorder should provide unique insights into genetic/molecular pathways contributing to the overall control of skeletal growth and development. We previously described and then demonstrated that the novel autosomal recessive osteolysis/arthritis syndrome, multicentric osteolysis with arthritis (MOA) (MIM #605156), was caused by inactivating mutations in the MMP2 gene [Al Aqeel, A. , Al Sewairi, W. , Edress, B. , Gorlin, R.J., Desnick, R.J. and Martignetti, J.A. (2000) Inherited multicentric osteolysis with arthritis: A variant resembling Torg syndrome in a Saudi family. Am. J. Med. Genet. , 93, 11-18. ]. These in vivo results were counterintuitive and unexpected since previous in vitro studies suggested that MMP-2 overexpression and increased activity, not deficiency, would result in the bone and joint features of MOA. The apparent lack of a murine model [Itoh, T. , Ikeda, T. , Gomi, H. , Nakao, S. , Suzuki, T. and Itohara, S. (1997) Unaltered secretion of beta-amyloid precursor protein in gelatinase A (matrix metalloproteinase 2)-deficient mice. J. Biol. Chem., 272, 22389-22392. ] has hindered studies on disease pathogenesis and, more fundamentally, in addressing the paradox of how functional loss of a single proteolytic enzyme results in an apparent increase in bone loss. Here, we report that Mmp2-/- mice display attenuated features of human MOA including progressive loss of bone mineral density, articular cartilage destruction and abnormal long bone and craniofacial development. Moreover, these changes are associated with markedly and developmentally restricted decreases in osteoblast and osteoclast numbers in vivo. Mmp2-/- mice have approximately 50% fewer osteoblasts and osteoclasts than control littermates at 4 days of life but these differences have nearly resolved by 4 weeks of age. In addition, despite normal cell numbers in vivo at 8 weeks of life, Mmp2-/- bone marrow cells are unable to effectively support osteoblast and osteoclast growth and differentiation in culture. Targeted inhibition of MMP-2 using siRNA in human SaOS2 and murine MC3T3 osteoblast cell lines resulted in decreased cell proliferation rates. Taken together, our findings suggest that MMP-2 plays a direct role in early skeletal development and bone cell growth and proliferation. Thus, Mmp2-/- mice provide a valuable biological resource for studying the pathophysiological mechanisms underlying the human disease and defining the in vivo physiological role of MMP-2.
Augmented Winter Ski with AR HMD

At time of writing, several affordable Head-Mounted Displays (HMD) are going to be released to the mass market, most of them for Virtual Reality (VR with Oculus Rift, Samsung Gear.) but also for indoor Augmented Reality (AR) with Hololens. We have investigated how to adapt such HMD as Oculus Rift for an outdoor AR ski slope. Rather than setting physical obstacles such as poles, our system employs AR to render dynamic obstacles by different means. During the demo, skiers will wear a video-see-through HMD while trying to ski on a real ski slope where AR obstacles are rendered.
Increasing the Level of IRS-1 and Insulin Pathway Sensitivity by Natural Product Carainterol A

Carainterol A is a eudesmane sesquiterpenoid extracted from Caragana intermedia. We have reported that carainterol A showed potent glucose consumption activity in C2C12 muscle cells and the db/db mouse model. However, the mechanism of the hypoglycemic effect of carainterol A remains elusive. In this article, we present a network pharmacology approach to predict the target and signaling pathway of carainterol A which was subsequently validated in HepG2 cells. It was demonstrated that carainterol A could increase the protein levels of IRS-1 and the downstream protein kinase AKT phosphorylation at a low micromolar level. These findings suggest that carainterol A can be a valuable lead compound and a promising chemical probe for the insulin signaling pathway.
Metabolomic analysis of insulin resistance across different mouse strains and diets

Insulin resistance is a major risk factor for many diseases. However, its underlying mechanism remains unclear in part because it is triggered by a complex relationship between multiple factors, including genes and the environment. Here, we used metabolomics combined with computational methods to identify factors that classified insulin resistance across individual mice derived from three different mouse strains fed two different diets. Three inbred ILSXISS strains were fed high-fat or chow diets and subjected to metabolic phenotyping and metabolomics analysis of skeletal muscle. There was significant metabolic heterogeneity between strains, diets, and individual animals. Distinct metabolites were changed with insulin resistance, diet, and between strains. Computational analysis revealed 113 metabolites that were correlated with metabolic phenotypes. Using these 113 metabolites, combined with machine learning to segregate mice based on insulin sensitivity, we identified C22:1-CoA, C2-carnitine, and C16-ceramide as the best classifiers. Strikingly, when these three metabolites were combined into one signature, they classified mice based on insulin sensitivity more accurately than each metabolite on its own or other published metabolic signatures. Furthermore, C22:1-CoA was 2.3-fold higher in insulin-resistant mice and correlated significantly with insulin resistance. We have identified a metabolomic signature composed of three functionally unrelated metabolites that accurately predicts whole-body insulin sensitivity across three mouse strains. These data indicate the power of simultaneous analysis of individual, genetic, and environmental variance in mice for identifying novel factors that accurately predict metabolic phenotypes like whole-body insulin sensitivity.
Outdoor Activity Recognition using Multi-Linked Temporal Processes

We develop Dynamically Multi-Linked Hidden Markov Models (DML-HMMs) for interpreting group activities involving multiple objects captured in an outdoor scene. The models are based on the discovery of salient dynamic interlinks among multiple different object events. A layered hierarchical DMLHMM is built using Schwarz’s Bayesian Information Criterion (BIC) based factorisation resulting in its topology being intrinsically determined by the underlying causality and temporal order among different object events. Our experiments demonstrate that the performance of a DML-HMM on modelling group activities in a noisy outdoor scene is superior compared to that of a Coupled Hidden Markov Model (CHMM).
How HCI-practitioners want to evaluate their own practice

How do individual HCI-practitioners evaluate their own work practice? And how would they like to evaluate it? Answers to these questions will give new knowledge on the state-of-the-practice in this area, and provide insight for researchers trying to improve practitioners' ability to evaluate their development project activities. The questions were investigated through questionnaire survey responses of 179 HCI-practitioners from the Nordic countries. It was found that the general maturity for evaluation of own practice were fairly high. However, the results indicate that HCI-practitioners tend not to evaluate their practice with regard to its impact on the development team and project leader; which may be counter productive to the downstream utility of HCI activities. Presentation of ongoing development of evaluation procedures, based on the results, will be included in the talk at NordiCHI 2006.
An action-oriented method for interprofessional organization development at a hospital operating unit

The complexity of modern interdisciplinary health care practices, where different specialties work together to solve complex problems, challenges traditional approaches to organizational development and quality improvement. An example of this is surgery. This article describes and evaluates an action-oriented method to facilitate organizational development and innovation at an operating unit, centered on interprofessional aspects of health care, a method that shares some features with action learning. At its core the method had a group with members from all specialties in an operating team, who participated in regular meetings facilitated by a process leader, according to experiential learning principles. The group was evaluated using mixed methods (including interaction process analysis (IPA)), of which video recorded group meetings and interviews constituted the main sources of data. Results showed that the group achieved a successful organizational change. Indications of the success of the group process were the low level of conflicts and the high level of task focus. Interprofessional boundaries appeared to be bridged as all members participated in formulation of both problems and solutions while not being afraid to voice different opinions. Problems could be attributed to lack of awareness of the group at the operating unit at which the intervention took place.
Positive maps, positive polynomials and entanglement witnesses

We link the study of positive quantum maps, block positive operators and entanglement witnesses with problems related to multivariate polynomials. For instance, we show how indecomposable block positive operators relate to biquadratic forms that are not sums of squares. Although the general problem of describing the set of positive maps remains open, in some particular cases we solve the corresponding polynomial inequalities and obtain explicit conditions for positivity.
Zero, pole and fragility of quantum systems

New fundamental limits on design and control of linear quantum systems are presented. A main difference between quantum and classical systems comes from the fact that quantum signals are represented by operator-valued vectors. The transfer function representation is useful to describe a system in the quantum setting for the same reason as it is useful classically. It is shown that the noncommutative property of quantum signals can be characterized by a specific relation between zeros and poles of a quantum transfer function. Then, two quantum mechanical tradeoffs follows from the transfer function constraint. One is a well known tradeoff, Heisenberg's uncertainty relation, and the other is a tradeoff between the ability of noise reduction and sensitivity to modeling error. While these tradeoffs hold at each frequency, quantum systems have another constraint between different frequencies based on Bode integral as classical systems usually do. In the quantum case, however, this constraint is also dependent on quantum mechanical parameters.
Influence of human absorption of Wi-Fi signal in indoor positioning with Wi-Fi fingerprinting

For outdoors, Global Network Navigation Systems have become the standard mechanism of positioning; but for indoor environments, there is still no standard system. Several mechanisms have been proposed and, among them, some of the more extended are those that use Wi-Fi signal for positioning, and mainly, those known as Wi-Fi fingerprinting. However, actual Wi-Fi mechanisms depends on environmental conditions: instability of Wi-Fi, differences in sensors of Smartphones, etc. One of these uncontrolled effects is the interaction between RF and human bodies. Human bodies interact with Wi-Fi radiation and, therefore, affects the signal received.
Estimating graph distance and centrality on shared nothing architectures

We present a parallel toolkit for pairwise distance computation in massive networks. Computing the exact shortest paths between a large number of vertices is a costly operation, and serial algorithms are not practical for billion‐scale graphs. We first describe an efficient parallel method to solve the single source shortest path problem on commodity hardware with no shared memory. Using it as a building block, we introduce a new parallel algorithm to estimate the shortest paths between arbitrary pairs of vertices. Our method exploits data locality, produces highly accurate results, and allows batch computation of shortest paths with 7% average error in graphs that contain billions of edges. The proposed algorithm is up to two orders of magnitude faster than previously suggested algorithms and does not require large amounts of memory or expensive high‐end servers. We further leverage this method to estimate the closeness and betweenness centrality metrics, which involve systems challenges dealing with indexing, joining, and comparing large datasets efficiently. In one experiment, we mined a real‐world Web graph with 700 million nodes and 12 billion edges to identify the most central vertices and calculated more than 63 billion shortest paths in 6 h on a 20‐node commodity cluster. Copyright © 2014 John Wiley & Sons, Ltd.