Miracle-dz/UniFAR-FTUs huggingface dataset:
Exotic meteoritic phenomena: The Tunguska event and anomalous low altitude fireballs -- manifestations of the mirror world?

There are a number of very puzzling meteoritic events including (a) The Tunguska event. It is the only known example of a low altitude atmospheric explosion. It is also the largest recorded event. Remarkably no fragments or significant chemical traces have ever been recovered. (b) Anomalous low altitude fireballs which (in some cases) have been observed to hit the ground. The absence of fragments is particularly striking in these cases, but this is not the only reason they are anomalous. On the other hand, there is strong evidence that most of our galaxy is made from exotic dark material - `dark matter'. Mirror matter is one well motivated dark matter candidate, since it is dark and stable and it is required to exist if particle interactions are mirror symmetric. If mirror matter is the dark matter, then some amount must exist in our solar system. We demonstrate that the mirror matter theory allows for a simple explanation for the puzzling meteoritic events [both (a) and (b)] if they are due to mirror matter space-bodies. A direct consequence of this explanation is that mirror matter fragments should exist in (or on) the ground at various impact sites. The properties of this potentially recoverable material depend importantly on the sign of the photon-mirror photon kinetic mixing parameter, $\epsilon$. We argue that the broad characteristics of the anomalous events suggests that $\epsilon$ is probably negative. Strategies for detecting mirror matter in the ground are discussed.
Investigating the Effect of Inter-organizational Factors ( Culture , structure , and strategy ) on the Success of Customer Relationship Management with Mediation of Knowledge Management in EN BANK , Tehran

Customer relationship management (CRM) with its emphasis on controlling and reducing the costs, and increasing the productivity results in reinforcing the value chain and clarification of policies and methods. In the other words, CRM includes all the steps an organization takes to create and develop a beneficial relationship with customers, and is defined as working within a team to achieve reliability and customer satisfaction. This paper investigates the effect of inter-organizational factors (organizational culture, structure and strategy) on the success of customer relationship management with mediation of knowledge management in Eghtesad Novin Bank (EN BANK) in Tehran, Iran. In this paper a combination of two models proposed by Garrido-Moreno et al. in 2011, and Zheng et al. in 2010 has been used as the research model. This research is of descriptive and applied type. To collect the required data, a questionnaire was distributed between 84 EN BANKS after verifying its validity. Then, Structural Equation Modeling Technique was used and it was found that the model parameters are in the desired state. The findings of the present study suggest that strategy as an inter-organizational factor has the greatest impact on the success of customer relationship management with mediation of knowledge management.
Optimal Scheduling and Allocation for IC Design Management and Cost Reduction

A large semiconductor product company spends hundreds of millions of dollars each year on design infrastructure to meet tapeout schedules for multiple concurrent projects. Resources (servers, electronic design automation tool licenses, engineers, and so on) are limited and must be shared -- and the cost per day of schedule slip can be enormous. Co-constraints between resource types (e.g., one license per every two cores (threads)) and dedicated versus shareable resource pools make scheduling and allocation hard. In this article, we formulate two mixed integer-linear programs for optimal multi-project, multi-resource allocation with task precedence and resource co-constraints. Application to a real-world three-project scheduling problem extracted from a leading-edge design center of anonymized Company X shows substantial compute and license costs savings. Compared to the product company, our solution shows that the makespan of schedule of all projects can be reduced by seven days, which not only saves ∼ 2.7% of annual labor and infrastructure costs but also enhances market competitiveness. We also demonstrate the capability of scheduling over two dozen chip development projects at the design center level, subject to resource and datacenter capacity limits as well as per-project penalty functions for schedule slips. The design center ended up purchasing 600 additional servers, whereas our solution demonstrates that the schedule can be met without having to purchase any additional servers. Application to a four-project scheduling problem extracted from a leading-edge design center in a non-US location shows availability of up to ∼ 37% headcount reduction during a half-year schedule for just one type of chip design activity.
For Which Children of Economic Disadvantage and in Which Instructional Contexts Does Earobics Step 1 Improve Kindergarteners’ Literacy?

Abstract This study evaluated Earobics Step 1, a commercial literacy program, and examined whether impact varied with children's school readiness and classroom instruction. Participants included 247 kindergarteners from 37 classrooms in nine Title 1 schools. Children were randomly assigned to receive 21 weeks of computerized instruction with Earobics or Building Blocks, a commercial mathematics program. Tests of phonological awareness (PA), graphophonemic knowledge, word reading, and vocabulary were administered at three points during the year, and standardized reading tests were administered at the end of year. Earobics did not consistently impact any outcome across children. However, it moderately accelerated PA development among children who started kindergarten with poor emergent literacy, and it positively impacted reading outcomes, but not PA, among children with relatively advanced emergent literacy. Earobics accelerated PA, graphophonemic knowledge, and reading development in classrooms where the teacher provided lots of instruction targeting oral language, PA, phonics, and writing. However it had no impact in classrooms where there was relatively little instruction targeting these skills or in classrooms where there was a lot of small group reading instruction.
Analysis of Virulence Genes Among Methicillin Resistant Staphylococcus aureus (MRSA) Strains

Background: Staphylococcus aureus is amongst major human pathogens both in hospitals and the community. This bacterium is an opportunistic pathogen responsible for a large number of self-limiting and even life-threatening diseases in humans. Methicillin resistant S. aureus (MRSA) strains are common causes of emerging nosocomial infections and are considered as a major problem for public health. Objectives: We aimed to study the profile of some virulence genes including: sea, seb, sed, tst, eta, etb, LuKS/F-PV, hla and hld in methicillin-resistant S. aureus by the PCR technique. Materials and Methods: A total of 345 isolates of S. aureus were collected from clinical specimens of patients referred to teaching hospitals of Shiraz; identification was done by biochemical (catalase, coagulase and DNase) and molecular tests. One hundred and forty six isolates of methicillin-resistant S. aureus (MRSA) were obtained and the presence of some toxin genes in these isolates was investigated by the polymerase chain reaction (PCR) technique. Results: The results showed that among the 345 isolates of S. aureus, 148 were confirmed as MRSA by screening with the cefoxitin disc diffusion (30 µg) method. Also among the 148 MRSA isolates, 146 isolates were confirmed as methicillin-resistant by molecular methods. The results showed that the frequency of methicillin-resistant and methicillin-sensitive S. aureus isolates during 2012 to 2013 in Namazi and Faghihi hospitals were 146 (42.3%) and 199 (57.7%), respectively. Besides, among the 146 confirmed MRSA isolates, 36.98% (54 isolates) and 63.02% (92 isolates) were related to female and male, respectively. The largest number of cases belonged to sputum samples (58 out of 146). The frequency of the eta, etb, sed, LuKS/F-PV, seb, tst, sea, hld and hla genes were 0.68%, 2.05%, 2.05%, 5.47%, 10.95%, 11.64%, 27.39%, 84.24% and 93.15%, respectively. In addition, amongst all examined genes, hla (93.15%) and eta (0.68%) genes had the highest and lowest frequencies, respectively. The greatest coexistence of genes was observed for the hla + hld gene combination (48.83%). The results of our study indicate that 98.63% of the isolates were positive for at least one of the virulence genes. Conclusions: The relative higher frequency of some virulence genes in this study may reflect the emergence of isolates containing these genes in Shiraz medical centers.
Ethanol tolerance in yeasts.

It is now certain that the inherent ethanol tolerance of the Saccharomyces strain used is not the prime factor regulating the level of ethanol that can be produced in a high sugar brewing, wine, sake, or distillery fermentation. In fact, in terms of the maximum concentration that these yeasts can produce under batch (16 to 17% [v/v]) or fed-batch conditions, there is clearly no difference in ethanol tolerance. This is not to say, however, that under defined conditions there is no difference in ethanol tolerance among different Saccharomyces yeasts. This property, although a genetic determinant, is clearly influenced by many factors (carbohydrate level, wort nutrition, temperature, osmotic pressure/water activity, and substrate concentration), and each yeast strain reacts to each factor differently. This will indeed lead to differences in measured tolerance. Thus, it is extremely important that each of these be taken into consideration when determining "tolerance" for a particular set of fermentation conditions. The manner in which each alcohol-related industry has evolved is now known to have played a major role in determining traditional thinking on ethanol tolerance in Saccharomyces yeasts. It is interesting to speculate on how different our thinking on ethanol tolerance would be today if sake fermentations had not evolved with successive mashing and simultaneous saccharification and fermentation of rice carbohydrate, if distillers' worts were clarified prior to fermentation but brewers' wort were not, and if grape skins with their associated unsaturated lipids had not been an integral part of red wine musts. The time is now ripe for ethanol-related industries to take advantage of these findings to improve the economies of production. In the authors' opinion, breweries could produce higher alcohol beers if oxygenation (leading to unsaturated lipids) and "usable" nitrogen source levels were increased in high gravity worts. White wine fermentations could also, if desired, match the higher ethanol levels in red wines if oxygenation (to provide the unsaturated lipids deleted in part by the removal of the grape skins) were practiced and if care were given to assimilable nitrogen concentrations. This would hold true even at 10 to 14 degrees C, and the more rapid fermentations would maximize utilization of winery tankage. (ABSTRACT TRUNCATED AT 400 WORDS)
Vanadium Concentration of Urine Rapid Colorimetric Method for Its Estimation

VANADIUM COMPOUNDS are used in dye, ink, and glass manufacture, as an alloy component in the steel industry, and as a catalyst in the production of sulfuric acid. Toxic exposures have been reported in the extraction of vanadium from ores and residues (1-5) and in the cleaning of burners fired with vanadium-bearing oil (6-8). The outstanding symptom associated with excessive inhalation of vanadium compounds, particularly the pentavalent forms, is acute irritation of the respiratory tract, sometimes attended by chemical pneumonitis (5). Irritation of the conjunctivae and eczematous lesions of the skin may also occur. Exposure to low levels of vanadium may cause metabolic disturbances as evidenced by a reduction in the fingernail cystine content (9). Talvitie and Wagner (10) have shown that urinary vanadium concentrations constitute a reliable index to the degree of absorption of vanadium. Although vanadium in urine may be determined accurately with the method described by Talvitie (11), the need arose in toxicologic investigations for a faster screening test to provide pilot information on the absorption of vanadium. For this purpose a simple, colorimetric test for vanadium in urine was devised. Necessary requirements for the test were (a) that only a small amount of urine be consumed in order to conserve the bulk of the sample for more accurate analysis, and (b) that the sensitivity be sufficient to detect minimal concentrations of vanadium. These conditions were met by basing the test on the catalytic effect of vanadium on the oxidation of organic chromogens by potassium chlorate. Szebelledy and Ajtai (12)
Global routing by iterative improvements for two-layer ball grid array packages

In current very large scale integration (VLSI) circuits, there can be hundreds of required I/O pins. Ball grid array (BGA) packaging is commonly used to realize the huge number of connections between VLSI chips and printed circuit boards (PCBs). In this paper, the authors propose a global-routing method by iterative improvements for two-layer BGA packages. In their routing model, the global routing for each net is uniquely determined by a via assignment. The proposed global-routing method begins with an initial feasible via assignment and incrementally improves the via assignment to minimize the maximum wire congestion and the total wire length. In each iteration, a via assignment is improved by exchanging two adjacent vias or by moving vias one by one to their adjacent grids. The algorithm efficiently generates better global routes than initial routes with respect to wire congestion and total wire length.
Protein and ginger for the treatment of chemotherapy-induced delayed nausea.

BACKGROUND Nausea that develops during the period that begins 24 hours after the administration of chemotherapy is called delayed nausea, and occurs in many patients with cancer. Meals high in protein decrease the nausea of motion sickness and pregnancy, possibly by reducing gastric dysrhythmias. Ginger also has antinausea properties. OBJECTIVES To explore the use of protein meals with ginger for the treatment of the delayed nausea of chemotherapy. DESIGN Twenty-eight (28) patients with cancer receiving chemotherapy for the first time were assigned to 1 of 3 groups. For 3 days beginning the day after their chemotherapy, Control Group patients continued with their normal diet, Protein Group patients consumed a protein drink and ginger twice daily, and High Protein Group patients consumed a protein drink with additional protein and ginger twice daily. OUTCOME MEASURES Patients recorded in a diary each day whether they had experienced nausea, whether their nausea had been frequent, whether their nausea had been bothersome, and whether they had needed any antiemetic medication. Gastric myoelectrical activity was assessed in 5 patients before and after ingestion of a high protein meal and ginger. RESULTS Reports of nausea, frequent nausea, and bothersome nausea were significantly less common among High Protein Group patients than among Control and Protein Group patients. Furthermore, significantly fewer patients in the High Protein Group used antiemetic medication. Differences between the Protein and Control groups were not statistically significant. In the 5 patients who had tests of gastric myoelectrical activity performed, a significant decrease in gastric dysrhythmia occurred after ingestion of the protein and ginger. CONCLUSIONS High protein meals with ginger reduced the delayed nausea of chemotherapy and reduced use of antiemetic medications. Protein with ginger holds the potential of representing a novel, nutritionally based treatment for the delayed nausea of chemotherapy.
Integration of SCADA in the information system

Information is most important thing now in 21st century. The many power utility company do not use information system for technical problems. This company work as before ten or fifty years. Only way for progress is insert information system into power utility system information system go into power utility company first as billing system. Next step is accounting, information system for accounting is very important for working any system. The financial sector of power system contains alls billing system, accounting and customer information service. The first segment of technical sector of power system where we implemented information system is SCADA. Next step is implementation of information system into network asset management and on end is GIS. We explain in this paper how are includes programs of many difference producer and connect into unique information system
A game of tag: MAPS catches up on RNA interactomes

ABSTRACT In the last few decades, small regulatory RNA (sRNA) molecules emerged as key regulators in every kingdom of life. Resolving the full targetome of sRNAs has however remained a challenge. To address this, we used an in vivo tagging MS2-affinity purification protocol coupled with RNA sequencing technology, namely MAPS, to assemble full bacterial small RNAs targetomes. The impressive potential of MAPS has been supported by a number of reports. Here, we concisely overview RNA-tagging history that preceded the development of the MAPS assay and expose the range of possible uses of this technology.
On Designing ULM-Based FPGA Logic Modules

In this paper, we give a method to design FPGA logic modules, based on an extension of classical work on designing Universal Logic Modules (ULM). Specifically, we give a technique to design a class of logic modules that specialize to a large number of functions under complementations and permutations of inputs, bridging of inputs and assignment of 0/1 to inputs. Thus, a lot of functions can be implemented using a single logic module. The significance of our work lies in our ability to generate a large set of such logic modules. A choice can be made from this set based on design criteria. We demonstrate the technique by generating a set of 471 8-input functions that have a much higher coverage than the 8-input cells employed by Actel's FPGAs. Our functions can specialize to up to 23 times the number of functions that Actel functions can. We also show that by carefully optimizing these functions one can obtain multi-level implementations of them that have delays within 10% of the delays of Actel modules. We demonstrate the effectiveness of these modules in mapping benchmark circuits. We observed a 16% reduction in area and a 21% reduction in delay using our logic modules instead of Actel's on these circuits.
Three dimensional bipedal stepping motion using neural oscillators-towards humanoid motion in the real world

CPG (central pattern generator) and entrainment dynamics together form a promising framework for robust and adaptive behavior generation for a high degree of freedom system in unstructured environment. This paper investigates its possibility in the domain of biped robotic locomotion. We extend a previous work on 2D biped locomotion using neural oscillators to 3D, introducing many more degrees of freedom and complexity in control. While the complexity of the problem has been increased, we have simplified the internal neural mechanism compared to the original 2D work. Our fully dynamic 3D simulation experiments showed that our mechanism can generate 3D stable biped stepping motion as well as tolerance against external perturbations.
Stress, Depression and Neuroplasticity

Modifications of signaling pathways and synapses owing to changing behaviors, environments, numerous neural modulation as well as brain-tissue injuries is defined as neuroplasticity in developmental neurology. The central purpose of the review is to gain a better understanding of the relation between stress, depression and neuroplasticity and explore potential therapeutic interventions for enhancing neural resilience. We have also reviewed the role of different factors like age, stress and sex on inducing neuroplasticity within various brain regions.
Performance of adaptive PI based on fuzzy logic for Indirect Vector Control Induction Motor drive

A Novel Adaptive PI based on Fuzzy Logic Reasoning (FLR) is presented in this paper for Indirect Vector Control (IVC) three phase Induction Motor (IM). The main objective is to achieve fast dynamic response and robustness for speed variation, parameter uncertainties, load disturbances, electrical faults perturbations, and to acquire maximum torque and efficiency. The d-q modeling of the IM in synchronously rotating reference frame and Space Vector Pulse Width Modulation (SVPWM) employed in power inverter are carried out in Matlab/Simulink. Both PI and Adaptive PI based on FLR are analyzed, designed, and simulated for IVC IM drive system. Furthermore, the critical and analytical assessment of the aforesaid designed control methodology provides robust and faster response with low overshoot, rise, and settling time for the load disturbances, parameter uncertainties, speed variation, and electrical faults perturbation of IVC IM drive system, compared to prior works.
Association between monoallelic TSHR mutations and congenital hypothyroidism: a statistical approach.

OBJECTIVE Biallelic TSHR mutations cause congenital hypothyroidism (CH). Serum TSH levels of monoallelic mutation carriers range from normal to mildly elevated, and thus the size of its effect remains unclear. The objectives were to examine the association between monoallelic TSHR mutations and positivity at newborn screening (NBS) for CH, and to test whether the association was modified by another genetic factor. SUBJECTS AND METHODS We enrolled 395 patients that had a positive result in NBS and sequenced TSHR. Monoallelic TSHR mutation carriers were further sequenced for DUOX2. Molecular functions of the mutations were verified in vitro. The frequency of the mutations in the study subjects was compared with a theoretical value in the Japanese general population. Odds ratio (OR) for NBS positivity associated with the mutation was calculated. Using Bayes' theorem, we estimated a posterior probability of NBS positivity given the mutation. RESULTS Twenty-six monoallelic TSHR mutation carriers were found. Four out of the 26 also had a monoallelic DUOX2 mutation (double heterozygotes). The frequencies of monoallelic TSHR mutation carriers (6.6%) and double heterozygotes (1.0%) were significantly higher than those in the general population (0.58% and 0.0087%, respectively). OR for NBS positivity of having a monoallelic TSHR mutation or being a double heterozygote was 12.0 or 117.9, respectively. Posterior probability of NBS positivity was 0.38% in monoallelic TSHR mutation carriers and 3.8% in double heterozygotes. CONCLUSIONS Monoallelic TSHR mutations are significantly associated with NBS positivity, and the association is further strengthened by the coexistence of monoallelic DUOX2 mutations.