Miracle-dz/UniFAR-FTUs huggingface dataset:
The structure of a semantic theory

JSTOR is a not-for-profit service that helps scholars, researchers, and students discover, use, and build upon a wide range of content in a trusted digital archive. We use information technology and tools to increase productivity and facilitate new forms of scholarship. For more information about JSTOR, please contact support@jstor.org. Linguistic Society of America is collaborating with JSTOR to digitize, preserve and extend access to Language. 1. Introduction. This paperl does not attempt to present a semantic theory of a natural language, but rather to characterize the form of such a theory. A semantic theory of a natural language is part of a linguistic description of that language. Our problem, on the other hand, is part of the general theory of language, fully on a par with the problem of characterizing the structure of grammars of natural languages. A characterization of the abstract form of a semantic theory is given by a metatheory which answers such questions as these: What is the domain of a semantic theory? What are the descriptive and explanatory goals of a semantic theory? What mechanisms are employed in pursuit of these goals? What are the empirical and methodological constraints upon a semantic theory? The present paper approaches the problem of characterizing the form of semantic theories by describing the structure of a semantic theory of English. There can be little doubt but that the results achieved will apply directly to semantic theories of languages closely related to English. The question of their applicability to semantic theories of more distant languages will be left for subsequent investigations to explore. Nevertheless, the present investigation will provide results that can be applied to semantic theories of languages unrelated to English and suggestions about how to proceed with the construction of such theories. We may put our problem this way: What form should a semantic theory of a natural language take to accommodate in the most revealing way the facts about the semantic structure of that language supplied by descriptive research? This question is of primary importance at the present stage of the development of semantics because semantics suffers not from a dearth of facts about meanings and meaning relations in natural languages, but rather from the lack of an adequate theory to organize, systematize, and generalize these facts. Facts about the semantics of natural languages have been contributed in abundance by many diverse fields, including philosophy, linguistics, philology, and …
Cell wall remodeling at the fission yeast cell division site requires the Rho-GEF Rgf3p

Cytokinesis in Schizosaccharomyces pombe is accompanied by several stages of cell wall remodeling at the division site. Coincident with actomyosin ring constriction, primary and secondary septa are deposited and then the primary septum is degraded to release daughter cells from one another. These steps require the activities of glucan synthases and glucanases, respectively, which must be coordinated with one another to prevent cell lysis. The lad1-1 mutation undergoes cell lysis specifically at cell division owing to the absence of the Rgf3p Rho1-guanine nucleotide exchange factor (GEF) at the division site. Electron microscopic analysis indicates that lysis occurs only as the primary septum begins to be degraded. Overproduction of either Rho1p or the previously uncharacterized Rab-GTPase-activating protein (GAP) involved in secretion, Gyp10p, suppresses lad1-1 lethality. Rgf3p is periodically produced in an Ace2p-dependent manner and localizes to the medial region of the cell early in mitosis, a pattern of expression distinct from the highly related Rho-GEF, Rgf1p. Although rgf1+ is not an essential gene, it is synthetically lethal with rgf2-deleted cells whereas no negative genetic interactions were detected between rgf2-deleted cells and lad1-1. Our data suggest that the three closely related fission yeast Rho-GEF molecules perform two distinct essential functions. Rgf3p appears necessary to stimulate Rho1p-mediated activation of a glucan synthase crucial after septation for proper new cell-end formation.
Image retrieval over networks: Ant algorithm for long term active learning

Image retrieval over a network is the focus of this paper, as being a major challenge of content based image retrieval. We present a system that gathers feedbacks given by the users in order to learn the location of the searched images. As a result, the active learning of a content based relevance function is enhanced by the selection of hosts containing relevant examples. We achieve a long term merging of feedbacks over many sessions, without any knowledge about the category being searched at any session. Our system is based on mobile agents crawling the network in an ant-like behavior. Markers are used to learn a routing of the agent leading them to the relevant images. The benefits of the ant-like agents system is a natural parallelization of the processing as well as a distributed approach to the routing learning. We made experiments on the trecvidpsila05 key-frame dataset showing that the location of the categories were efficiently learned. Furthermore, the long-term learning of categories improves the interaction by reducing the number of labels needed during the interaction to obtain satisfying results.
Local and Global Processes in Visual Completion

In the natural environment, objects are frequently occluded, and people continuously complete partly occluded objects Do local processes or global processes control the completion of partly occluded objects? To answer this question, most previous studies simply asked subjects to draw the completions they “saw” Such drawing tasks are highly subjective, and they provide equivocal results Our studies are the first to use an objective, implicit paradigm (primed matching) to determine the extent to which local or global processes underlie the visual completion of partly occluded objects Our results suggest that global processes dominate perceptual completion, whereas local processes do not play a large role Therefore, local theories of completion, or theories in which local processes dominate, cannot be entirely correct
Effect of Anti‐CD 20 Antibody Rituximab in Patients with Post‐Transplant Lymphoproliferative Disorder (PTLD)

Post‐transplant lymphoproliferative disorders (PTLD) are a life‐threatening complication following solid organ transplantation. Treatment with rituximab, a humanized anti‐CD20 monoclonal antibody, has proved to be a promising approach and shown a low toxicity profile. Between February 1999 and April 2002, we conducted a multicentre phase II trial investigating rituximab as single agent in 17 patients with PTLD. Transplanted organs were heart (n = 5), kidney (n = 4), lung (n = 4) and liver (n = 4). Patients were treated with four weekly doses of 375 mg/m2 of rituximab. The mean follow‐up time is 24.2 months. Histology was distributed in 10 diffuse large cell‐, 2 marginal zone‐, 1 Burkitt‐like lymphoma, 1 Hodgkin‐like PTLD and 3 polymorphic lymphoproliferations. Therapy was well tolerated and no severe adverse events were observed. The mean overall survival period is 37.0 months with 11 patients still living. In total, 9 patients (52.9%) achieved a complete remission, with a mean duration of 17.8 months. Partial remission was observed in 1 patient, minor remission in 2 patients, no change in 3 patients and 1 patient experienced progressive disease. Two patients relapsed, at intervals 3 and 5 months after obtaining complete remission. Rituximab proved to be well tolerated and effective in the treatment of PTLD.
Lipid Raft in Cardiac Health and Disease

Lipid rafts are sphingolipid and cholesterol rich micro-domains of the plasma membrane that coordinate and regulate varieties of signaling processes. Lipid rafts are also present in cardiac myocytes and are enriched in signaling molecules and ion channel regulatory proteins. Lipid rafts are receiving increasing attention as cellular organelles contributing to the pathogenesis of several structural and functional processes including cardiac hypertrophy and heart failure. At present, very little is known about the role of lipid rafts in cardiac function and dysfunction. This review will discuss the possible role of lipid rafts in cardiac health and disease.
Compressive epsilon photography for post-capture control in digital imaging

A traditional camera requires the photographer to select the many parameters at capture time. While advances in light field photography have enabled post-capture control of focus and perspective, they suffer from several limitations including lower spatial resolution, need for hardware modifications, and restrictive choice of aperture and focus setting. In this paper, we propose "compressive epsilon photography," a technique for achieving complete post-capture control of focus and aperture in a traditional camera by acquiring a carefully selected set of 8 to 16 images and computationally reconstructing images corresponding to all other focus-aperture settings. We make the following contributions: first, we learn the statistical redundancies in focal-aperture stacks using a Gaussian Mixture Model; second, we derive a greedy sampling strategy for selecting the best focus-aperture settings; and third, we develop an algorithm for reconstructing the entire focal-aperture stack from a few captured images. As a consequence, only a burst of images with carefully selected camera settings are acquired. Post-capture, the user can then select any focal-aperture setting of choice and the corresponding image can be rendered using our algorithm. We show extensive results on several real data sets.
Application specific 1200V planar and trench IGBTs

We compare planar and trench non-punch through (NPT) insulated gate bipolar transistors (IGBT) static and dynamic characteristics and evaluate them for motor drive, UPS, IH (induction heating) and switched mode power supply applications. The power supply market is mostly driven by high speed power devices and is presently dominated by MOSFET. The uninterruptible power supply (UPS) IGBTs need moderately high speed switching where as motor drive applications need low conduction loss and moderate switching speed devices. Some of these applications need good short circuit withstand time (SCWT). The planar IGBT has more SCWT and avalanche capability and is better suited for motor control. On the other hand, trench IGBT has better tradeoff curve and hence is a good choice for power supplies and IH markets. These new high speed NPT IGBTs can become cost effective for applications such as UPS, motor drive, IH as well as SMPS market by reducing overall loss over other 1200V IGBTs and regular 1000-1200 volts MOSFETs. By using these IGBTs, the efficiency can be improved or other trade off such as cost reduction, size reduction or increase in power density may be implemented. The new NPT IGBTs reduce both the switching and conduction losses over other 1200V IGBTs and MOSFETs. The turn-off switching loss was reduced by 40-60% compared to previous generation IGBTs and the conduction loss was reduced drastically compared to MOSFETs and IGBTs, especially at high junction temperature. NPT2 planar IGBT offers best of both worlds - lower cost and better performance
Personalized Tamoxifen: A Step Closer but Miles To Go

Genetic variants in CYP2D6 lead to reduced conversion of tamoxifen to the active metabolite endoxifen. However, the role of the CYP2D6 genotype in predicting tamoxifen-associated outcomes remains controversial. Accurate assignment of the CYP2D6 genotype in archival tissues is crucial for future studies attempting to determine risk prediction of outcomes in tamoxifen-treated individuals. Clin Cancer Res; 16(17); 4308–10. ©2010 AACR.
Antimicrobial properties of diacetyl

Diacetyl preparations from three commercial sources were found to be essentially similar when tested primarily against a set of 40 cultures, including 10 of lactic acid bacteria, 4 of yeasts, 12 of gram-positive non-lactic acid bacteria, and 14 of gram-negative bacteria. The compound was effective at pH less than or equal to 7.0 and progressively ineffective at pH greater than 7.0. The lactic acid bacteria were essentially unaffected by concentrations between 100 and 350 micrograms/ml over the pH range of 5.0 to 7.0. Of the 12 gram-positive non-lactic acid bacteria, 11 were inhibited by 300 micrograms/ml at pH less than or equal to 7.0. The three yeasts and the 13 gram-negative bacteria that grew at pH 5.5 were inhibited by 200 micrograms/ml. Diacetyl was ineffective against four clostridia under anaerobic conditions. It was lethal for gram-negative bacteria and generally inhibitory for gram-positive bacteria. Nongrowing cells were not affected. The effectiveness of diacetyl was considerably less in brain heart infusion broth, Trypticase soy agar, and cooked-meat medium than in nutrient broth or plate count agar. The antimicrobial activity was antagonized by glucose, acetate, and Tween 80 but not by gluconic acid. As an antimicrobial agent, diacetyl was clearly more effective against gram-negative bacteria, yeasts, and molds than against gram-positive bacteria.
Natural Resource Ecology and Management 2-2008 Landscape Genetics and the Spatial Distribution of Chronic Wasting Disease

Predicting the spread of wildlife disease is critical for identifying populations at risk, targeting surveillance and designing proactive management programmes. We used a landscape genetics approach to identify landscape features that influenced gene flow and the distribution of chronic wasting disease (CWD) in Wisconsin whitetailed deer. CWD prevalence was negatively correlated with genetic differentiation of study area deer from deer in the area of disease origin (core-area). Genetic differentiation was greatest, and CWD prevalence lowest, in areas separated from the core-area by the Wisconsin River, indicating that this river reduced deer gene flow and probably disease spread. Features of the landscape that influence host dispersal and spatial patterns of disease can be identified based on host spatial genetic structure. Landscape genetics may be used to predict high-risk populations based on their genetic connection to infected populations and to target disease surveillance, control and preventative activities.
Association between plasma leptin levels and diabetes mellitus.

BACKGROUND Leptin is an important adipose tissue-derived hormone that has been shown to be involved in pathophysiological mechanisms related to cardiovascular disease and diabetes. However, few studies have examined the association between plasma leptin and diabetes mellitus in humans. Also, it is not clear if this association is present among women as well as in men. Therefore, we examined the association between plasma leptin levels and diabetes mellitus in a representative multiethnic sample of U.S. adults. METHODS We examined the 1988-1994 third National Health and Nutrition Examination Survey (NHANES III) participants >20 years of age (n = 5,599, 54.7% women). Plasma leptin levels were categorized into quartiles (women, <7.68 fg/L, 7.68-13.18 fg/L, 13.19-21.70 fg/L, >21.70 fg/L; men, <2.64 fg/L, 2.64-4.36 fg/L, 4.37-7.12 fg/L, >7.12 fg/L). Diabetes mellitus was defined as fasting glucose ≥126 mg/dL, non-fasting glucose ≥200 mg/dL or use of oral hypoglycemic medication or insulin (n = 395). RESULTS Higher plasma leptin levels were initially found to be associated with diabetes mellitus after adjusting for age, sex, race/ethnicity, education, smoking, alcohol intake, hypertension, serum cholesterol and C-reactive protein [odds ratio (OR), 3.79; confidence interval (CI), 2.05-7.00; P trend <0.0001). However, when we additionally adjusted for body mass index (BMI), the association between plasma leptin levels and diabetes mellitus disappeared in both men (OR, 1.07; CI, 0.59-1.94; P trend = 0.5004) and women (OR, 0.86; CI, 0.49-1.51; P trend = 0.2819). CONCLUSION Higher plasma leptin levels are not independently associated with diabetes mellitus after adjustment for BMI. The null association was evident both in women as well as in men.
Late referral to palliative care consultation service: length of stay and in-hospital mortality outcomes.

BACKGROUND Palliative care services in the United States are increasing in their prevalence but continue to vary in their implementation, with different referral policies and timing of patient access to services. OBJECTIVE To better define a late referral and to understand the association of late referrals to palliative care with patient health outcomes, including postreferral length of hospital stay and in-hospital mortality. METHODS We performed a retrospective study using multiple linear and logistic regressions on 1,225 patients with pre-existing oncologic diagnoses who received a referral to Stanford Hospital's palliative care service. RESULTS Those oncologic patients who were referred to palliative care in the first week following admission had significantly shorter lengths of stay after referral, as well as lower in-hospital mortality, compared with patients who were referred later than 1 week following admission. Regression analyses, adjusted for demographic variables, DNR status, and sickness, revealed that waiting 1 week or longer to refer a patient was associated with an overall increased length of stay of 2.70 days (P < .001). This increased to 3.40 days (P < .001) when patients who died in the hospital were removed from the data, suggesting that in-hospital mortality was not solely responsible for the trend. Waiting 1 week to refer was associated with increased odds of a patient's dying in the hospital vs being discharged alive by a factor of 3.04 (P < .001). LIMITATIONS This study was limited to analyzing inpatient palliative care consultation services with a emphasis on patients with metastatic solid tumors. We used a proxy for patient sickness burden but did not analyze outcomes specific to cancer stage or individual oncologic diagnosis separately. CONCLUSIONS Our study suggests that late referrals may have a marked negative impact on health outcomes, which argues for the design and implementation of hospital policies that encourage early referral to palliative care for advanced cancer patients.
A Study of Narcissism, Affiliation, Intimacy, and Power Motives among Students in Business Administration

This research examined the intercorrelations of scores on narcissism and the motives for affiliation, intimacy, and power. 65 students in a Master's program for business administration were given the Narcissistic Personality Inventory and the Thematic Apperception Test. A significant difference in narcissism was found between men and women. Men and women also were significantly different on the need for intimacy. Narcissism was significantly and negatively correlated with the need for intimacy and significantly and positively correlated with the need for power. The hypothesized association between narcissism and the need for affiliation was not substantiated.
Forced use of the upper extremity in chronic stroke patients: results from a single-blind randomized clinical trial.

BACKGROUND AND PURPOSE Of all stroke survivors, 30% to 66% are unable to use their affected arm in performing activities of daily living. Although forced use therapy appears to improve arm function in chronic stroke patients, there is no conclusive evidence. This study evaluates the effectiveness of forced use therapy. METHODS In an observer-blinded randomized clinical trial, 66 chronic stroke patients were allocated to either forced use therapy (immobilization of the unaffected arm combined with intensive training) or a reference therapy of equally intensive bimanual training, based on Neuro-Developmental Treatment, for a period of 2 weeks. Outcomes were evaluated on the basis of the Rehabilitation Activities Profile (activities), the Action Research Arm (ARA) test (dexterity), the upper extremity section of the Fugl-Meyer Assessment scale, the Motor Activity Log (MAL), and a Problem Score. The minimal clinically important difference (MCID) was determined at the onset of the study. RESULTS One week after the last treatment session, a significant difference in effectiveness in favor of the forced use group compared with the bimanual group (corrected for baseline differences) was found for the ARA score (3.0 points; 95% CI, 1.3 to 4.8; MCID, 5.7 points) and the MAL amount of use score (0.52 points; 95% CI, 0.11 to 0.93; MCID, 0.50). The other parameters revealed no significant differential effects. One-year follow-up effects were observed only for the ARA. The differences in treatment effect for the ARA and the MAL amount of use scores were clinically relevant for patients with sensory disorders and hemineglect, respectively. CONCLUSIONS The present study showed a small but lasting effect of forced use therapy on the dexterity of the affected arm (ARA) and a temporary clinically relevant effect on the amount of use of the affected arm during activities of daily living (MAL amount of use). The effect of forced use therapy was clinically relevant in the subgroups of patients with sensory disorders and hemineglect, respectively.
Increasing neurofilament subunit NF-M expression reduces axonal NF-H, inhibits radial growth, and results in neurofilamentous accumulation in motor neurons

The carboxy-terminal tail domains of neurofilament subunits neurofilament NF-M and NF-H have been postulated to be responsible for the modulation of axonal caliber. To test how subunit composition affects caliber, transgenic mice were generated to increase axonal NF- M. Total neurofilament subunit content in motor and sensory axons remained essentially unchanged, but increases in NF-M were offset by proportionate decreases in both NF-H and axonal cross-sectional area. Increase in NF-M did not affect the level of phosphorylation of NF-H. This indicates that (a) in vivo NF-H and NF-M compete either for coassembly with a limiting amount of NF-L or as substrates for axonal transport, and (b) NF-H abundance is a primary determinant of axonal caliber. Despite inhibition of radial growth, increase in NF-M and reduction in axonal NF-H did not affect nearest neighbor spacing between neurofilaments, indicating that cross-bridging between nearest neighbors does not play a crucial role in radial growth. Increase in NF- M did not result in an overt phenotype or neuronal loss, although filamentous swellings in perikarya and proximal axons of motor neurons were frequently found.
Primary Ewing’s Sarcoma/Primitive Neuroectodermal Tumor (ES/PNET) of the Penis

Ewing’s sarcomas/primitive neuroectodermal tumors (ES/PNETs) arise from a multipotent progenitor cell and are considered to be of neuroectodermal derivation. Most tumors commonly arise in the skeletal system, which are the classic ES/PNET and occasionally occur in the soft tissue of extraskeletal sites, which are named extraskeletal Ewing’s sarcomas (EES/PNET). This study reports a case of a 28-year-old man with primary EES/PNET of the penis.
AGV in Japan-recent trends of advanced research, development, and industrial applications

Recent trends on advanced AGV are reviewed and discussed with examples. Special concern is made for automated position finding, guidance and multivehicle strategies, as well as communication systems. Focused are on engineering, electromechanical and optical problems. In addition to conventional manufacturing and advanced industrial applications, service vehicles such as floor cleaning, blind aids and off-road uses are described. New electric power supply systems are also presented. <<ETX>>