Miracle-dz/UniFAR-FTUs huggingface dataset:
Basic dynamical systems control of aeroengine flow

The notions of basic controllability and basic control are defined using dynamical systems theory of partial differential equations. A quadratic optimal control of the linearized viscous Moore-Greitzer equation is presented and it is confirmed that stall is uncontrollable in this model. A basic control is constructed for the nonlinear viscous Moore-Greitzer equation which can control both surge and stall. Numerical simulations of the basic control are presented.
Comparative efficacy and complications of long-acting and intermediate-acting insulin regimens for adults with type 1 diabetes: an individual patient data network meta-analysis

Objective To examine the comparative efficacy and complications of long-acting and intermediate-acting insulin for different patient characteristics for type 1 diabetes mellitus (T1DM). Design Systematic review and individual patient data (IPD) network meta-analysis (NMA). Data sources MEDLINE, EMBASE and the Cochrane Central Register of Controlled Trials were searched through June 2015. Eligibility criteria Randomised controlled trials (RCTs) on adults with T1DM assessing glycosylated haemoglobin (A1c) and severe hypoglycaemia in long-acting and intermediate-acting insulin regimens. Data extraction and synthesis We requested IPD from authors and funders. When IPD were not available, we used aggregate data. We conducted a random-effects model, and specifically a one-stage IPD-NMA for those studies providing IPD and a two-stage IPD-NMA to incorporate those studies not providing IPD. Results We included 28 RCTs plus one companion report, after screening 6680 titles/abstracts and 205 full-text articles. Of the 28 RCTs, 27 studies provided data for the NMA with 7394 participants, of which 12 RCTs had IPD on 4943 participants. The IPD-NMA for A1c suggested that glargine once daily (mean difference [MD]=−0.31, 95% confidence interval [CI]: −0.48 to −0.14) and detemir once daily (MD=−0.25, 95% CI: –0.41 to −0.09) were superior to neutral protamine Hagedorn (NPH) once daily. NPH once/two times per day improved A1c compared with NPH once daily (MD=−0.30, 95% CI: –0.50 to −0.11). Results regarding complications in severe hypoglycaemia should be considered with great caution due to inconsistency in the evidence network. Accounting for missing data, there was no evidence of inconsistency and long-acting insulin regimens ranked higher regarding reducing severe hypoglycaemia compared with intermediate-acting insulin regimens (two-stage NMA: glargine two times per day SUCRA (Surface Under the Cumulative Ranking curve)=89%, detemir once daily SUCRA=77%; one-stage NMA: detemir once daily/two times per day SUCRA=85%). Using multiple imputations and IPD only, complications in severe hypoglycaemia increased with diabetes-related comorbidities (regression coefficient: 1.03, 95% CI: 1.02 to 1.03). Conclusions Long-acting insulin regimens reduced A1c compared with intermediate-acting insulin regimens and were associated with lower severe hypoglycaemia. Of the observed differences, only glargine once daily achieved a clinically significant reduction of 0.30%. Results should be interpreted with caution due to very low quality of evidence. PROSPERO registration number CRD42015023511.
Anosov representations and proper actions

We establish several characterizations of Anosov representations of word hyperbolic groups into real reductive Lie groups, in terms of a Cartan projection or Lyapunov projection of the Lie group. Using a properness criterion of Benoist and Kobayashi, we derive applications to proper actions on homogeneous spaces of reductive groups.
Exploring the Development of Nursing Clinical Judgment Among Students Using Virtual Reality Simulation

Background: Virtual reality simulation (VRS) is an emerging pedagogy in nursing education. Purpose: The purpose of this qualitative exploratory study was 2-fold: to determine nursing students' learning experiences when engaged in VRS, and to explore learners' problem-solving/clinical reasoning approach after participation in a VRS clinical scenario. This article reports student descriptions of clinical reasoning/clinical judgment when considering their VRS experience. Methods: Qualitative description provided a methodological orientation for the study. Widely accepted frameworks for nursing clinical judgment provided a theoretical basis. Results: Focus group participant narratives reveal evidence about nursing clinical judgment when applied to established descriptions and phases. Conclusion: Study findings suggest that VRS experiences promote development of nursing clinical judgment among students.
On 0-cycles with modulus

Given a smooth surface $X$ over a field and an effective Cartier divisor $D$, we provide an exact sequence connecting $CH_0(X,D)$ and the relative $K$-group $K_0(X,D)$. We use this exact sequence to answer a question of Kerz and Saito whenever $X$ is a resolution of singularities of a normal surface. This exact sequence is used to show that the localization sequence for ordinary Chow groups does not extend to Chow groups with modulus.
Allen–Cahn approximation of mean curvature flow in Riemannian manifolds, II: Brakke's flows

We prove convergence of solutions to the parabolic Allen–Cahn equation to Brakke's motion by mean curvature in Riemannian manifolds with Ricci curvature bounded from below. Our results hold for a general class of initial conditions and extend previous results from [T. Ilmanen, Convergence of the Allen–Cahn equation to the Brakke's motion by mean curvature, J. Differential Geom. 31 (1993) 417–461] even in Euclidean space. We show that a sequence of measures, associated to energy density of solutions of the parabolic Allen–Cahn equation, converges in the limit to a family of rectifiable Radon measures, which evolves by mean curvature flow in the sense of Brakke. A key role is played by nonpositivity of the limiting energy discrepancy and a local almost monotonicity formula (a weak counterpart of Huisken's monotonicity formula) proved in [Allen–Cahn approximation of mean curvature flow in Riemannian manifolds, I, uniform estimates, to appear in Ann. Sc. Norm. Super. Pisa Cl. Sci.; arXiv:1308.0569], to get various density bounds for the limiting measures.
A Linear, Decoupled and Energy stable scheme for smectic-A Liquid Crystal Flows

In this paper, we consider numerical approximations for the model of smectic-A liquid crystal flows. The model equation, that is derived from the variational approach of the de Gennes free energy, is a highly nonlinear system that couples the incompressible Navier-Stokes equations, and two nonlinear coupled second-order elliptic equations. Based on some subtle explicit--implicit treatments for nonlinear terms, we develop a unconditionally energy stable, linear and decoupled time marching numerical scheme. We also rigorously prove that the proposed scheme obeys the energy dissipation law at the discrete level. Various numerical simulations are presented to demonstrate the accuracy and the stability thereafter.
Maladaptive behaviors in children with autism and parental hopelessness: The moderating role of parental reflective functioning

Hopelessness in parents has implications for parents' own well‐being as well as their ability to meet the needs of their children. In the present study, we examined the effect of maladaptive behaviors in children with autism on parental hopelessness, with particular attention to whether parental reflective functioning would moderate the effect of maladaptive behaviors on parental hopelessness. Our sample included 68 parents of children with autism between the ages of 3 and 18. Findings revealed a significant positive relationship between maladaptive behaviors in the children and hopelessness in the parents. Moreover, parental reflective functioning moderated the effect of child maladaptive behaviors on parental hopelessness, such that children's maladaptive behaviors were positively associated with parental hopelessness in parents with low (but not high) reflective functioning. Findings suggest parental reflective functioning may be a protective factor against parental hopelessness, and thus a possible target for interventions for hopelessness in parents whose children with autism exhibit greater maladaptive behaviors.
Ricci flow on surfaces with conical singularities, II

This is a continuation of our previous work on Ricci flow on surfaces with conical singularities [16]. For smooth surfaces, in 1982, Hamilton [8] used his Ricci flow to prove the (normalized) Ricci flow converges to a metric of constant curvature in a given conformal class. Chow [5], Chen, Lu and Tian [3] removed various technical conditions to show that Ricci flow can be used as a tool to prove the Uniformization theorem. Let S be a smooth Riemann surface and p ∈ S. A metric g on S is said to have a conical singularity of order β(β > −1), or of angle θ = (2π(β + 1)) at p, if in a neighborhood U , g = w(z) |z| 2β |dz| 2 , where z is a conformal coordinate in U with z(p) = 0 and w is some continuous positive function. In general, consider a divisor β = ∑n i=1 βipi and a conformal metric g on S which has a conical singularity of order βi at pi. The set of all such metrics is a singular conformal class, which we denote by (S, β). We are interested in generalizing the theory about Ricci flow to surfaces with conical singularities. In particular, we hope Ricci flow could be a useful tool in the study of canonical metric in the conformal class (S, β). There are already several papers devoted to this subject, for example, [10], [13], [14]. It suffices for us to note here that not all (S, β) admits a metric of constant curvature and it is still an open question to find a ’canonical’ metric in (S, β) for general S and β. We refer to [2], [9], [1] for related study. In [16], the author showed that there is a reasonable notion of normalized Ricci flow despite that the metric is not complete at the cone tips. For a ’good’ initial value, there is a family of metrics g(t), t ∈ [0, T ] in the conformal class (S, β) satisfying
SCAF4‐related syndromic intellectual disability

The causal link between variants in the SCAF4 gene and a syndromic form of intellectual disability (ID) was established in 2020 by Fliedner et al. Since then, no additional cases have been reported. We performed exome sequencing in a 16‐year‐old Brazilian male presenting with ID, epilepsy, behavioral problems, speech impairment, facial dysmorphisms, heart malformations, and obesity. A de novo pathogenic variant [SCAF4(NM_020706.2):c. 374_375dup(p.Glu126LeufsTer20)] was identified. This is the second study reporting the involvement of SCAF4 in syndromic ID, and the description of the patient's clinical features contributes to defining the phenotypic spectrum of this recently described Mendelian disorder.
The Gysin homomorphism for homogeneous spaces via residues - PhD Thesis

The subject of this dissertation is the Gysin homomorphism in equivariant cohomology for spaces with torus action. We consider spaces which are quotients of classical semisimple complex linear algebraic groups by a parabolic subgroup with the natural action of a maximal torus, the so-called partial flag varieties. We derive formulas for the Gysin homomorphism for the projection to a point, of the form \[\int_X \alpha = Res_{\mathbf{z}=\infty} \mathcal{Z}(\mathbf{z}, \mathbf{t}) \cdot \alpha(\mathbf{t}),\] for a certain residue operation and a map $\mathcal{Z}(\mathbf{z}, \mathbf{t})$, associated to the root system. The mentioned description relies on two following generalizations of theorems in symplectic geometry. We adapt to the equivariant setting (for torus actions) the Jeffrey--Kirwan nonabelian localization and a theorem relating the cohomology of symplectic reductions by a compact Lie group and by its maximal torus, following the approach by Martin. Applying the generalized theorems to certain contractible spaces acted upon by a product of unitary groups we derive the push-forward formula for partial flag varieties of types $A$, $B$, $C$ and $D$.
Distinguished properties of the gamma process and related topics

We study fundamental properties of the gamma process and their relation to various topics such as Poisson–Dirichlet measures and stable processes. We prove the quasi-invariance of the gamma process with respect to a large group of linear transformations. We also show that it is a renormalized limit of the stable processes and has an equivalent sigma-ﬁnite measure (quasi-Lebesgue) with important invariance properties. New properties of the gamma process can be applied to the Poisson—Dirichlet measures. We also emphasize the deep similarity between the gamma process and the Brownian motion. The connection of the above topics makes more transparent some old and new facts about stable and gamma processes, and the Poisson-Dirichlet measures.
The multitaskers of the brain: Glial responses to viral infections and associated post‐infectious neurologic sequelae

Many viral infections cause acute and chronic neurologic diseases which can lead to degeneration of cortical functions. While neurotropic viruses that gain access to the central nervous system (CNS) may induce brain injury directly via infection of neurons or their supporting cells, they also alter brain function via indirect neuroimmune mechanisms that may disrupt the blood–brain barrier (BBB), eliminate synapses, and generate neurotoxic astrocytes and microglia that prevent recovery of neuronal circuits. Non‐neuroinvasive, neurovirulent viruses may also trigger aberrant responses in glial cells, including those that interfere with motor and sensory behaviors, encoding of memories and executive function. Increasing evidence from human and animal studies indicate that neuroprotective antiviral responses that amplify levels of innate immune molecules dysregulate normal neuroimmune processes, even in the absence of neuroinvasion, which may persist after virus is cleared. In this review, we discuss how select emerging and re‐emerging RNA viruses induce neuroimmunologic responses that lead to dysfunction of higher order processes including visuospatial recognition, learning and memory, and motor control. Identifying therapeutic targets that return the neuroimmune system to homeostasis is critical for preventing virus‐induced neurodegenerative disorders.
USP7 regulates the ncPRC1 Polycomb axis to stimulate genomic H2AK119ub1 deposition uncoupled from H3K27me3

Ubiquitin-specific protease 7 (USP7) has been implicated in cancer progression and neurodevelopment. However, its molecular targets remain poorly characterized. We combined quantitative proteomics, transcriptomics, and epigenomics to define the core USP7 network. Our multi-omics analysis reveals USP7 as a control hub that links genome regulation, tumor suppression, and histone H2A ubiquitylation (H2AK119ub1) by noncanonical Polycomb-repressive complexes (ncPRC1s). USP7 strongly stabilizes ncPRC1.6 and, to a lesser extent, ncPRC1.1. Moreover, USP7 represses expression of AUTS2, which suppresses H2A ubiquitylation by ncPRC1.3/5. Collectively, these USP7 activities promote the genomic deposition of H2AK119ub1 by ncPRC1, especially at transcriptionally repressed loci. Notably, USP7-dependent changes in H2AK119ub1 levels are uncoupled from H3K27me3. Even complete loss of the PRC1 catalytic core and H2AK119ub1 has only a limited effect on H3K27me3. Besides defining the USP7 regulome, our results reveal that H2AK119ub1 dosage is largely disconnected from H3K27me3.
Self-blame predicts anxiety and depression in infertile couples who opt for in vitro fertilisation (IVF) treatment

ABSTRACT The study examined the use of maladaptive coping strategies such as conflict, avoidance and self-blame in predicting anxiety and depression in couples undergoing IVF procedure. The target group consisted of 80 couples who started the IVF treatment at the Division of Obstetrics and Gynaecology, Ljubljana’s University Medical Centre in Slovenia. The participants completed three scales: S/T Anxiety Inventory, CES Depression Scale, and Marital Coping Inventory. The results showed increased rates of depression compared to the normative population; 18% of women and 14% of men reported mild to moderate depression or the possibility of major depression. Women showed higher anxiety scores than men. Coping strategies predicted both depression and anxiety, with self-blame being the most toxic one. The study showed that self-blame is a coping strategy that should be properly addressed in the couples at the very outset of IVF treatment, to decrease emotional disorders and increase the likability of a succesful IVF medical procedures.
A Galileon Primer

Elementary features of galileon models are discussed at an introductory level. Following a simple example, a general formalism leading to a hierarchy of field equations and Lagrangians is developed for flat spacetimes. Legendre duality is discussed. Implicit and explicit solutions are then constructed and analyzed in some detail. Galileon shock fronts are conjectured to exist. Finally, some interesting general relativistic effects are studied for galileons coupled minimally to gravity. Spherically symmetric galileon and metric solutions with naked curvature singularities are obtained and are shown to be separated from solutions which exhibit event horizons by a critical curve in the space of boundary data.
From Unit to Dose: A Machine Learning Approach for Precise Prediction of Hemoglobin and Iron Content in Individual Packed Red Blood Cell Units

Transfusion of packed red blood cells (pRBCs) saves lives, but iron overload limits survival of chronically transfused patients. Quality control methods, which involve entering pRBC units and removing them from the blood supply, reveal that hemoglobin (38.5–79.9 g) and heme iron (133.42–276.89 mg) vary substantially between pRBCs. Yet, neither hemoglobin nor iron content can be quantified for individual clinically used pRBCs leading to rules of thumb for pRBC transfusions. Keeping their integrity, the authors seek to predict hemoglobin/iron content of any given pRBC unit applying eight machine learning models on 6,058 pRBCs. Based on thirteen features routinely collected during blood donation, production and quality control testing, the model with best trade‐off between performance and complexity in hemoglobin/iron content prediction is identified. Validation of this model in an independent cohort of 2637 pRBCs confirms an adjusted R2 > 0.9 corresponding to a mean absolute prediction error of ≤1.43 g hemoglobin/4.96 mg iron (associated standard deviation: ≤1.13 g hemoglobin/3.92 mg iron). Such unprecedented precise prediction enables reliable pRBC dosing per pharmaceutically active agent, and monitoring iron uptake in patients and individual iron loss in donors. The model is implemented in a free open source web application to facilitate clinical application.
A stability of vector bundles with twisted sections and the Donaldson-Thomas instantons on compact K\"{a}hler threefolds

We consider a version of Hermitian-Einstein equation but perturbed by a Higgs field with a solution called a Donaldson-Thomas instanton on compact K\"ahler threefolds. The equation could be thought of as a generalization of the Hitchin equation on Riemann surfaces to K\"ahler threefolds. In the appendix of arXiv:0805.2192, following an analogy with the Hitchin equation, we introduced a stability condition for a pair consisting of a locally-free sheaf over a compact K\"ahler threefold and a section of the associated sheaf of the endomorphisms tensored by the canonical bundle of the threefold. In this article, we prove a Hitchin--Kobayashi-type correspondence for this and the Donaldson-Thomas instanton on compact K\"ahler threefolds.
Error estimates for a numerical approximation to the compressible barotropic Navier-Stokes equations

We present here a general method based on the investigation of the relative energy of the system, that provides an unconditional error estimate for the approximate solution of the barotropic Navier Stokes equations obtained by time and space discretization. We use this methodology to derive an error estimate for a specific DG/finite element scheme for which the convergence was proved in [27]. This is an extended version of the paper submitted to IMAJNA.
Effect of Aerobic Exercise on Arterial Stiffness in Individuals with Different Smoking Statuses

Abstract This study aimed to investigate the immediate effects of acute bout of aerobic exercise on arterial stiffness in individuals with different smoking statuses. A total of 940 male individuals (mean age of 36.82±7.76 years) in the Kailuan study cohort were selected to participate in the fifth National Physical Fitness Monitoring. All participants completed measurements of brachial – ankle pulse wave velocity (baPWV) before and after twice-quantitative cycle ergometer exercise. Four groups were defined: (1) non-smokers (n=231), (2) former smokers (n=165), (3) light smokers (1–10 cigarettes/day, n=254), (4) heavy smokers (>10 cigarettes/day, n=290). Generalized linear models were established to analyze between-group differences in the change in baPWV before and after acute aerobic exercise in individuals with different smoking statuses. Overall, after acute aerobic exercise, baPWV was immediately decreased significantly (−33.55 cm/s [95% CI, − 39.69 to −27.42]). Compared with non-smokers, former smokers, light smokers, and heavy smokers showed a greater decrease in baPWV (−12.17 cm/s [95%CI, − 30.08 to 5.75], − 18.43 cm/s [95%CI, −34.69 to − 2.16], and −22.46 cm/s [95%CI, − 38.39 to − 6.54]) respectively. There is a transient decrease in baPWV in individuals with different smoking statuses. Compared with non-smokers, baPWV decreased more significantly in light and heavy smokers.
Deconvolution of metal apportionment in bulk metal-organic frameworks

We report a general route to decipher the apportionment of metal ions in bulk metal-organic frameworks (MOFs) by solid-state nuclear magnetic resonance spectroscopy. We demonstrate this route in Mg1−xNix-MOF-74, where we uncover all eight possible atomic-scale Mg/Ni arrangements through identification and quantification of the distinct chemical environments of 13C-labeled carboxylates as a function of the Ni content. Here, we use magnetic susceptibility, bond pathway, and density functional theory calculations to identify local metal bonding configurations. The results refute the notion of random apportionment from solution synthesis; rather, we reveal that only two of eight Mg/Ni arrangements are preferred in the Ni-incorporated MOFs. These preferred structural arrangements manifest themselves in macroscopic adsorption phenomena as illustrated by CO/CO2 breakthrough curves. We envision that this nondestructive methodology can be further applied to analyze bulk assembly of other mixed-metal MOFs, greatly extending the knowledge on structure-property relationships of MOFs and their derived materials.
Black hole entropy in modified-gravity models

An analysis of some modified-gravity models, based on the study of pure Schwarzschild and of Schwarzschild-de Sitter black holes, and involving the use of the Noether charge method, is carried out. Corrections to the classical Einsteinian black hole entropy appear. It is shown explicitly how the condition of positive entropy can be used in order to constrain the viability of modified-gravity theories.