Miracle-dz/UniFAR-FTUs huggingface dataset:
A Review of the Literature

This paper is a review of research in product development, which we define as the trans-1 formation of a market opportunity into a product available for sale. Our review is broad, encompassing work in the academic fields of marketing, operations management, and engineering design. The value of this breadth is in conveying the shape of the entire research landscape. We focus on product development projects within a single firm. We also devote our attention to the development of physical goods, although much of the work we describe applies to products of all kinds. We look inside the "black box" of product development at the fundamental decisions that are made by intention or default. In doing so, we adopt the perspective of product development as a deliberate business process involving hundreds of decisions, many of which can be usefully supported by knowledge and tools. We contrast this approach to prior reviews of the literature, which tend to examine the importance of environmental and contextual variables, such as market growth rate, the competitive environment , or the level of top-management support.
Barycentric parameterizations for isotropic BRDFs

A bidirectional reflectance distribution function (BRDF) is often expressed as a function of four real variables: two spherical coordinates in each of the "incoming" and "outgoing" directions. However, many BRDFs reduce to functions of fewer variables. For example, isotropic reflection can be represented by a function of three variables. Some BRDF models can be reduced further. In This work, we introduce new sets of coordinates which we use to reduce the dimensionality of several well-known analytic BRDFs as well as empirically measured BRDF data. The proposed coordinate systems are barycentric with respect to a triangular support with a direct physical interpretation. One coordinate set is based on the BRDF mode) proposed by Lafortune. Another set, based on a model of Ward, is associated with the "halfway" vector common in analytical BRDF formulas. Through these coordinate sets we establish lower bounds on the approximation error inherent in the models on which they are based. We present a third set of coordinates, not based on any analytical model, that performs well in approximating measured data. Finally, our proposed variables suggest novel ways of constructing and visualizing BRDFs.
Big-fish-little-pond effect on academic self-concept. A cross-cultural (26-country) test of the negative effects of academically selective schools.

Academically selective schools are intended to affect academic self-concept positively, but theoretical and empirical research demonstrates that the effects are negative. The big-fish-little-pond effect (BFLPE), an application of social comparison theory to educational settings, posits that a student will have a lower academic self-concept in an academically selective school than in a nonselective school. This study, the largest cross-cultural study of the BFLPE ever undertaken, tested theoretical predictions for nationally representative samples of approximately 4,000 15-year-olds from each of 26 countries (N = 103,558) who completed the same self-concept instrument and achievement tests. Consistent with the BFLPE, the effects of school-average achievement were negative in all 26 countries (M beta = -.20, SD = .08), demonstrating the BFLPE's cross-cultural generalizability.
Microcirculatory Inflammation in Chronic Venous Insufficiency: Current Status and Future Directions

One of the hallmarks of chronic venous insufficiency (CVI) is an elevated venous pressure. However, no direct link at the cellular and molecular levels between venous hypertension and actual tissue damage in CVI has been established. Evidence for generation of an inflammatory reaction and several molecular alterations in the development of CVI is discussed. Development of experimental models of CVI, analysis of the mechanical tissue stresses in addition to venous hypertension, in combination with systematic studies of clinically stratified and standardized patient‐derived samples is required for molecular description of the pathogenesis of CVI.
The intestinal microbiota in the rat model: major breakthroughs from new technologies

Abstract The mammalian intestine harbors a large and diverse community of micro-organisms, known as the intestinal microbiota. Recent developments in molecular profiling methods, mainly based on microbial 16S ribosomal RNA gene sequencing, have provided unprecedented insights into the make-up and diversity of intestinal microbial communities. Using these culture-independent analyses, gut microbiota of several mammals including laboratory rodents, have been revisited. The laboratory rat is one of the major species bred and kept for scientific research. Although this animal is bred in confined environments and subjected to procedures for satisfying health requirements that hamper natural colonization, some major features of mammalian gut microbiota are conserved. However, the gut microbiota varies according to the breeding conditions of the rats and this could impact reproducibility of the experimental models. Determining the non-pathogenic microbial community might be relevant in standards of quality control of laboratory animals. Molecular profiling techniques could be applied to document this information.
International Journal of Pure and Applied Sciences and Technology Effects of Growth Medium and Planting Density on Growth and Flowering Characteristics Carnation

This research was done to investigate the comparative effects of different potting media with different compositions and planting density on growth and flowering of carnation chaubad. Different substrates including cocopeat+ pearlit+ vermicompost (10,60,30%), cocopeat+ pearlit+ vermicompost(20,60,20%), and cocopeat+ pearlit (40,60%), with density one and three plant in each pot were used. The experiment was carried out in completely randomized design. The data for parameters analyzed statistically showed significant effect of media combinations and density. Each treatment was consisted of 1 or 3 plants and was replicated thrice. Plants parameters of growth and flowering such as Flower length(cm), Flower diameter (cm), Root length (cm), Stem length (cm), Fresh weight (g) and Longevity (day) indicated using of growth medium content 20%vermecompost with density one in each pot is more useful than the other medium and density that were used in the study.
Improving Robustness in Complex Tasks for a Supervisor Operated Humanoid

Complex manipulation tasks in uncontrolled environments are challenged with errors from multiple sources that can prevent successful completion. We describe a framework for the decomposition of a complex task into behaviors for a supervisor controlled robot. A classification of behaviors based on the actors and dominant motion is used to analyze the success rate. Three methods to improve robustness are presented: reduction in length of robot-environment manipulation by using robot-only prepositioning behaviors, behavior definition using environmental constraints, and supervisor fine tuning during sub-task switching. We show the application of this framework for the wall task in the DARPA Robotics Challenge. The framework produces a robust successful implementation of the wall task with a duration of less than 10 min.
Probing the cosmic reionization history and local environment of gamma‐ray bursts through radio dispersion

We discuss the effect of dispersion delay due to intervening ionized media in the radio emission of gamma-ray bursts (GRBs). For high-redshift GRBs (z ≥ 3), the ionized intergalactic medium (IGM) should be the dominant source of dispersion without substantial local or foreground contamination, offering a unique probe of the cosmic reionization epoch through measures of the free-electron column density out to different redshifts. The delay times from z ∼ 10 can be ∼1 h at 100 MHz and ∼10 h at 30 MHz. On the other hand, dispersion by local ionized material may be important for GRBs at lower redshifts if they occur inside or behind dense molecular clouds, providing clues to the GRB environment; free-free absorption may also be significant in this case. Detecting dispersion delay in the known radio afterglow emission should be extremely challenging due to the low fluxes at the relevant frequencies, but may be marginally possible for rare, bright afterglows by the Square Kilometer Array. If GRBs also emit prompt, coherent radio emission as predicted by Sagiv & Waxman, the observational prospects can be much better; detection of a sufficient sample of high-z GRBs by the Low-Frequency Array may allow discrimination of different reionization histories. Interesting constraints on the low-redshift, warm-hot IGM may also be obtainable through dispersion.
Coming to Terms with Environmental Justice in Outdoor Recreation: A Conceptual Discussion with Research Implications

Much of the research on environmental justice centers on environmental hazards. This article offers an overview of the emergence of environmental justice issues in outdoor recreation management and research. The authors argue that a major challenge to future research on environmental justice in outdoor recreation is clarifying definitions of environmental justice and generating awareness of the different dimensions of environmental justice. The authors also examine recent empirical studies of environmental justice issues related to outdoor recreation and other resource amenities. Based on an overview of the literature and these recent studies, the authors set forth some broad outlines to guide future research.
A massively space-time parallel N-body solver

We present a novel space-time parallel version of the Barnes-Hut tree code PEPC using PFASST, the Parallel Full Approximation Scheme in Space and Time. The naive use of increasingly more processors for a fixed-size N-body problem is prone to saturate as soon as the number of unknowns per core becomes too small. To overcome this intrinsic strong-scaling limit, we introduce temporal parallelism on top of PEPC's existing hybrid MPI/PThreads spatial decomposition. Here, we use PFASST which is based on a combination of the iterations of the parallel-in-time algorithm parareal with the sweeps of spectral deferred correction (SDC) schemes. By combining these sweeps with multiple space-time discretization levels, PFASST relaxes the theoretical bound on parallel efficiency in parareal. We present results from runs on up to 262,144 cores on the IBM Blue Gene/P installation JUGENE, demonstrating that the spacetime parallel code provides speedup beyond the saturation of the purely space-parallel approach.
Refinement-based guidelines for developing structured programs

The development of structured programs is carried out either using bottom-up techniques, or top-down techniques; we show how refinement and proof can be used to help in the top-down development of structured imperative programs. When a problem is stated, the incremental proof-based methodology of event B starts by stating a very abstract model and further refinements lead to finer-grain event-based models which are used to build an algorithm. In this paper, the main idea is to consider each procedure call as an abstract event of a model corresponding to the development of the procedure; generally, a procedure is specified by a pre/post specification and then the refinement process can lead to a set of events, which are then combined to obtain the body of the procedure. It means that the abstraction corresponds to the procedure call and the body is derived by the refinement process. The refinement process may also use recursive procedures and it supports the top-down refinement. The technique is illustrated by the sorting problem.
Light-induced Photoreceptor Apoptosis in Vivo Requires Neuronal Nitric-oxide Synthase and Guanylate Cyclase Activity and Is Caspase-3-independent*

Apoptosis is the mode of photoreceptor cell death in inherited and induced retinal degeneration. However, the molecular mechanisms of photoreceptor cell death in human cases and animal models of retinal dystrophies remain undefined. Exposure of Balb/c mice to excessive levels of white light results in photoreceptor apoptosis. This study delineates the molecular events occurring during and subsequent to the induction of retinal degeneration by exposure to white light in Balb/c mice. We demonstrate an early increase in intracellular calcium levels during photoreceptor apoptosis, an event that is accompanied by significant superoxide generation and mitochondrial membrane depolarization. Furthermore, we show that inhibition of neuronal nitric-oxide synthase (nNOS) by 7-nitroindazole is sufficient to prevent retinal degeneration implicating a key role for neuronal nitric oxide (NO) in this model. We demonstrate that inhibition of guanylate cyclase, a downstream effector of NO, also prevents photoreceptor apoptosis demonstrating that guanylate cyclase too plays an essential role in this model. Finally, our results demonstrate that caspase-3, frequently considered to be one of the key executioners of apoptosis, is not activated during retinal degeneration. In summary, the data presented here demonstrate that light-induced photoreceptor apoptosis in vivo is mediated by the activation of nNOS and guanylate cyclase and is caspase-3-independent.
Natural Convection in a Cavity Partially Filled with a Vertical Porous Medium

The shear stress jump boundary condition that must be imposed at an interface between a porous medium and a free fluid in an enclosure is investigated. Two-domain approach is founded and finite element method is used to solve the problem. Three stress jump coefficients 0, 1, -1 are analyzed for different Rayleigh number, permeability and thickness of porous layer. Variation of Maximum stream function and Nusselt number show stronger convection and heat transfer when the stress jump coefficient is positive. There is little distinctive in flow and heat transfer when the value of coefficient is equal to 0 and -1.
Seasonal mood variation: an epidemiological study in northern Norway

In an epidemiological study carried out in the town of Tromsö in northern Norway an extensive questionnaire was sent twice, in summer and winter, to 1000 subjects to investigate the degree of symptoms of mood variation (depression or hypomania) during the polar winter night and midnight sun seasons. The results suggest that the general population north of the Arctic Circle shows a major seasonal mood variation. It is suggested that seasonal mood variation is a chronobiological mood disturbance related to and probably precipitated by extreme variations in light. The therapeutic implications and preventive measures are discussed.
Occupational burnout, eating behavior, and weight among working women.

BACKGROUND Eating behavior affects weight and thus the development of obesity. Studies on the effect of occupational burnout (exhaustive fatigue, cynicism, and lost occupational self-respect caused by chronic work stress) on eating behavior are lacking. OBJECTIVE The objective was to investigate associations between occupational burnout, eating behavior, and weight among working women. DESIGN A total of 230 working women participated in a randomized controlled intervention trial (Nuadu) that aimed at changing the health behaviors of those with health risks. We assessed eating behavior using the Three-Factor Eating Behavior Questionnaire 18 and burnout using the Bergen Burnout Indicator 15 at both baseline and 12 mo. Body weight and percentage body fat were also measured at baseline and at 12 mo. The intervention and control groups were combined and divided by burnout and weight-change variables. RESULTS Women experiencing burnout at baseline had significantly higher scores in emotional eating (EE; P = 0.002) and uncontrolled eating (UE; P = 0.001) than did those without burnout. A significant difference was found between the change in UE from baseline to 12 mo in those with and without burnout (P = 0.05). UE decreased significantly among those without burnout at baseline (P < 0.001). CONCLUSIONS Those experiencing burnout may be more vulnerable to EE and UE and have a hindered ability to make changes in their eating behavior. We recommend that burnout should be treated first and that burnout and eating behavior should be evaluated in obesity treatment.
Face Recognition Using Double Dimension Reduction

— In this paper a new approach to face recognition is presented that achieves double dimension reduction making the system computationally efficient with better recognition results. In pattern recognition techniques, discriminative information of image increases with increase in resolution to a certain extent, consequently face recognition results improve with increase in face image resolution and levels off when arriving at a certain resolution level. In the proposed model of face recognition, first image decimation algorithm is applied on face image for dimension reduction to a certain resolution level which provides best recognition results. Due to better computational speed and feature extraction potential of Discrete Cosine Transform (DCT) it is applied on face image. A subset of coefficients of DCT from low to mid frequencies that represent the face adequately and provides best recognition results is retained. A trade of between decimation factor, number of DCT coefficients retained and recognition rate with minimum computation is obtained. Preprocessing of the image is carried out to increase its robustness against variations in poses and illumination level. This new model has been tested on different databases which include ORL database, Yale database and a color database. The proposed technique has performed much better compared to other techniques. The significance of the model is two fold: (1) dimension reduction up to an effective and suitable face image resolution (2) appropriate DCT coefficients are retained to achieve best recognition results with varying image poses, intensity and illumination level.
Vehicular Delay-Tolerant Networks?A Novel Solution for Vehicular Communications

Vehicular Delay-Tolerant Networks (VDTNs) is a breakthrough based DTN-based solution to provide vehicular communications under challenging scenarios characterized by long delays and sporadic connections. VDTN uses a store-carry-and-forward paradigm, inspirited from Delay Tolerant Networks, which allows forward bundles to asynchronously reach the destination hop by hop over traveling vehicles equipped with short-range Wi-Fi devices. The proposed VDTN architecture assumes out-of-band signaling with control and data planes separation. VDTNs also assume datagrams aggregation under the network layer in large size packets, called bundles, following an IP over VDTN approach. This paper presents VDTN networks focusing on their layered architecture, bundle aggregation and de-aggregation mechanisms, network protocols, scheduling and dropping policies, fragmentation mechanisms, and the created tools for VDTNs performance evaluation, demonstration, and validation.
Loss of miRNA biogenesis induces p19Arf-p53 signaling and senescence in primary cells

Dicer, an enzyme involved in microRNA (miRNA) maturation, is required for proper cell differentiation and embryogenesis in mammals. Recent evidence indicates that Dicer and miRNA may also regulate tumorigenesis. To better characterize the role of miRNA in primary cell growth, we generated Dicer-conditional mice. Ablation of Dicer and loss of mature miRNAs in embryonic fibroblasts up-regulated p19Arf and p53 levels, inhibited cell proliferation, and induced a premature senescence phenotype that was also observed in vivo after Dicer ablation in the developing limb and in adult skin. Furthermore, deletion of the Ink4a/Arf or p53 locus could rescue fibroblasts from premature senescence induced by Dicer ablation. Although levels of Ras and Myc oncoproteins appeared unaltered, loss of Dicer resulted in increased DNA damage and p53 activity in these cells. These results reveal that loss of miRNA biogenesis activates a DNA damage checkpoint, up-regulates p19Arf-p53 signaling, and induces senescence in primary cells.
Genomic Characterization of H14 Subtype Influenza A Viruses in New World Waterfowl and Experimental Infectivity in Mallards (Anas platyrhynchos)

Recent repeated isolation of H14 hemagglutinin subtype influenza A viruses (IAVs) in the New World waterfowl provides evidence to suggest that host and/or geographic ranges for viruses of this subtype may be expanding. In this study, we used genomic analyses to gain inference on the origin and evolution of H14 viruses in New World waterfowl and conducted an experimental challenge study in mallards (Anas platyrhynchos) to evaluate pathogenicity, viral replication, and transmissibility of a representative viral strain in a natural host species. Genomic characterization of H14 subtype IAVs isolated from New World waterfowl, including three isolates sequenced specifically for this study, revealed high nucleotide identity among individual gene segments (e.g. ≥95% shared identity among H14 HA gene segments). In contrast, lower shared identity was observed among internal gene segments. Furthermore, multiple neuraminidase subtypes were observed for H14 IAVs isolated in the New World. Gene segments of H14 viruses isolated after 2010 shared ancestral genetic lineages with IAVs isolated from wild birds throughout North America. Thus, genomic characterization provided evidence for viral evolution in New World waterfowl through genetic drift and genetic shift since purported introduction from Eurasia. In the challenge study, no clinical disease or lesions were observed among mallards experimentally inoculated with A/blue-winged teal/Texas/AI13-1028/2013(H14N5) or exposed via contact with infected birds. Titers of viral shedding for mallards challenged with the H14N5 IAV were highest at two days post-inoculation (DPI); however shedding was detected up to nine DPI using cloacal swabs. The distribution of viral antigen among mallards infected with H14N5 IAV was largely restricted to enterocytes lining the villi in the lower intestinal tract and in the epithelium of the bursa of Fabricius. Characterization of the infectivity of A/blue-winged teal/Texas/AI13-1028/2013(H14N5) in mallards provides support for similarities in viral replication and shedding as compared to previously described waterfowl-adapted, low pathogenic IAV strains in ducks.
New Complexity Results for Classical Planning Benchmarks

The 3rd and 4th International Planning Competitions have enriched the set of benchmarks for classical propositional planning by a number of novel and interesting planning domains. Although they are commonly used for the purpose of evaluating planner performance, the planning domains themselves have not yet been studied in depth. In this contribution, we prove complexity results for the decision problems related to finding some plan, finding an optimal sequential plan, and finding an optimal parallel plan in these planning domains. Our results also provide some insights into the question why planning is hard for some of the domains under consideration.