Miracle-dz/UniFAR-FTUs huggingface dataset:
Continuous muscle activity, Morvan's syndrome and limbic encephalitis: ionic or non ionic disorders?

SUMMARY The early pathophysiologic study showed increasing evidence that autoimmunity is implicated in the pathogenesis of neuromyotonia. Antibodies to voltage gated potassium channel were detected in the serum of patients who had peripheral nerves hyperexcitability and also Morvan's disease or limbic encephalitis. These discoveries offered new approaches to treatments. Recently, antibodies previously attributed to VGKC recognise 2 surface antigens LGI1 and CASPR2 into the VGKC complex. Finally, VGKC antibodies are directed to 2 proteins the first one is a key hippocampic protein containing pre and post synaptic proteins. The second one CASPR2 is an hippocampic and paranodal protein. There clinical significance is different: hyperexcitability, limbic encephalitis without thymoma for LGI1, hyperexcitability, Morvan limbic encephalitis and frequent thymoma for CASPR2. In conclusion, the term NMT - LE - VGKC should be changed to NMT- LE with LGI1 and CASPR2 antibodies and classified as auto immune synaptic disorders. Mutations in genes encoding both these proteins are found in hereditary epilepsy and other syndromes. Various potassium channelopathies are closely linked to Morvan's syndromes. A new classification of antibodies will be necessary.
Aggression in Sexually Abused Trafficked Girls and Efficacy of Intervention

The broad objective of this study was to understand the incidence and severity of aggression among sexually abused girls who were trafficked and who were then further used for commercial sexual exploitation (referred to subsequently as sexually abused trafficked girls). In addition, the impact of counseling for minimizing aggression in these girls was investigated. A group of 120 sexually abused trafficked Indian girls and a group of 120 nonsexually abused Indian girls, aged 13 to 18, participated in the study. The sexually abused trafficked girls were purposively selected from four shelters located in and around Kolkata, India. The nonsexually abused girls were selected randomly from four schools situated near the shelters, and these girls were matched by age with the sexually abused trafficked girls. Data were collected using a Background Information Schedule and a standardized psychological test, that is, The Aggression Scale. Results revealed that 16.7% of the girls were first sexually abused between 6 and 9 years of age, 37.5% between 10 and 13 years of age, and 45.8% between 14 and 17 years of age. Findings further revealed that 4.2% of the sexually abused trafficked girls demonstrated saturated aggression, and 26.7% were highly aggressive, that is, extremely frustrated and rebellious. Across age groups, the sexually abused trafficked girls suffered from more aggression (p < .05), compared with the nonvictimized girls. Psychological interventions, such as individual and group counseling, were found to have a positive impact on the sexually abused trafficked girls. These findings should motivate counselors to deal with sexually abused children. It is also hoped that authorities in welfare homes will understand the importance of counseling for sexually abused trafficked children, and will appoint more counselors for this purpose.
The Relationship Between Emotional Intelligence, Relationship Between Emotional Intelligence, Organizational Justice, Job Satisfaction and Organizational Commitment Personnel,of the Personnal of PourSina Hospital ,Rasht

Introduction: The advantages of some organizations over others, are the employees in those organizations whose level of loyalty and commitment causes the duties to be performed with higher quality.The sensitivity of this issue in hospitals could be in the spotlight. Objectives: The aim of this study was to investigate the relationship between emotional intelligence, organizational justice, job satisfaction and organizational commitment in the largest trauma hospital (Poursina) in the north of Iran. Materials and Methods: The survey was a cross-sectional one and statistical population included all physicians, nurses, radiology staff, administrative and the services personnel of Pour-sina hospital in Rasht. Totally, 216 individuals were selected by Quota sampling and responded to demographic information, emotional intelligence, organizational justice, job satisfaction and organizational commitment questionnaires. All data were analyzed by SPSS software version 16. Results: Multiple Regression Analysis revealed that three predictive variables of social awareness (β=0.324, P<0.0001), procedural justice (β=0.286, P<0.0001), and duration of education (β=-0.248, P<0.0001) could significantly explain %19 of the shared variance of organizational commitment (F= 15.037,P<0.0001). Conclusion: The organizational commitment is the major factor affecting the quality of hospital services, and managers of such therapeutic centers can improve their levels of organizational commitment by promoting the social awareness and adhering to procedural justice, especially in personnel with high education. Conflict of interest: non declared
Cardiopulmonary resuscitation and ethics

The earliest documentation of cardiopulmonary resuscitation (CPR) dates to the Old Testament, which describes how the prophet Elisha resuscitated an apparently dead child by blowing air into his mouth. (1) Modern CPR began in 1960 with the landmark study by Kouwenhoven, Jude, and Knickerbocker, which reported combining closed chest compression, mouth-to-mouth breathing, and external defibrillation. (1) Since that time, CPR and advanced cardiac life support (ACLS) techniques have saved many lives but have also raised several ethical dilemmas. Consent for CPR procedures is universally presumed. However, there are times when patients' right to receive CPR contrasts with their caregivers' impression that such treatment is not medically indicated. Conversely, some patients receive resuscitation that they would not have wanted. Decisions regarding resuscitation and the duration of resuscitative efforts often entail several crucial ethical issues. This article will focus on the ethical dilemmas related to the need to make critical decisions in emergency or acute settings.
Continual HTN Robot Task Planning in Open-Ended Domains: A Case Study

The fact that many AI planning approaches are still based on too simplifying assumptions makes it often hard to apply these approaches to real-world robotics. In particular, it is in many cases difficult to generate a complete plan in advance, because not all information is available at the beginning of the planning process. We briefly present the continual planning system ACogPlan and a preliminary test case that demonstrates how the planning system can enable mobile robots to continually plan and execute activities in an open-ended domain.
What impedes the development of professional learning communities in China? Perceptions from leaders and frontline teachers in three schools in Shanghai

Using qualitative data collected from three high schools in Shanghai, this study explored the barriers to the development of professional learning communities (PLCs) in Chinese schools from the perspectives of school leaders and teachers. Results indicate that the barriers identified by teachers in the development of PLCs include insufficient collaborative time, ineffective school leadership, unfavourable accountability policy, and lack of collaborative professional culture. By contrast, school leaders regard the absence of financial power, passive teachers, an unfavourable accountability system, and shortage of external resources as the major impediments to PLCs. Moreover, both similarities and differences are observed in the perceptions of teachers and school leaders regarding the barriers to PLC development. Practical implications for the effective implementation of PLCs and suggestions for future research are also presented.
Selfish Routers and the Price of Anarchy

We revisit Roughgarden and Tardos’s price of anarchy in network routing, in a new model in which routing decisions are made by the edgesas opposed to the flows. We propose two models: the latency modelin which edges seek to minimize the average latency of the flow through them on the basis of knowledge of latency conditions in the whole network, and the pricing modelin which edges advertise pricing schemes to their neighbors and seek to maximize their profit. We show the counterintuitive result that the price of stability in the latency model is Ω(n 1 60 ), even with linear latencies (as compared with 4 3 for the case in which routing decisions are made by the flows themselves). However, in the pricing modelin which edges advertise pricing schemes — functions dictating how the price varies as a function of the total amount of flow — we show the surprising result that, under a condition ruling out monopolistic situations, all Nash equilibria have societally optimal flows; that is, the price of anarchy in this model isone. University of California, Berkeley. Email: christos@cs.berkeley. edu . University of California, Berkeley. Work supported under a National Science Foundation Graduate Research Fellowship. Email: gvaliant@cs.berkeley. edu .
On subband analysis based on glottal-ARMAX speech model

We have already developed a speech analysis method based on the Glottal-ARMAX (Auto Regressive and Moving Average eXogenous) model, in which the speech production model is supposed to be an ARMAX vocal tract model and two kinds of excitation: glottal source model excitation and white Gaussian. The speech analysis method based on the Glottal-ARMAX model can estimate the glottal source and ARMAX model parameters simultaneously with pitch synchronous. In this paper, a subband processing with QMF lterbank or Haar lterbank is introduced to the Glottal-ARMAX method in order to reduce the computation. The introduction makes it possible to reduce computation since the orders of ARMAX identication can be set smaller than that of fullband analysis. The introduction also enables to improve an estimation accuracy of the glottal source model parameters owing to the improved resolution in the frequency domain.
Comparison between Teichmüller and Lipschitz metrics

We study the Lipschitz metric on a Teichmüller space (defined by Thurston) and compare it with the Teichmüller metric. We show that in the thin part of the Teichmüller space the Lipschitz metric is approximated up to a bounded additive distortion by the sup‐metric on a product of lower‐dimensional spaces (similar to the Teichmüller metric as shown by Minsky). In the thick part, we show that the two metrics are equal up to a bounded additive error. However, these metrics are not comparable in general; we construct a sequence of pairs of points in the Teichmüller space, with distances that approach zero in the Lipschitz metric while they approach infinity in the Teichmüller metric.
An action / state-based model-checking approach for the analysis of an asynchronous protocol for Service-Oriented Applications ?

In this paper we present an action/state-based logical framework for the analysis and verification of complex systems, which relies on the definition of doubly labelled transition systems. The defined temporal logic, called UCTL, combines the action paradigm—classically used to describe systems using labelled transition systems—with predicates that are true over states—as captured when using Kripke structures as semantic model. An efficient model checker for UCTL has been realized, exploiting an on-the-fly algorithm. We then show how to use UCTL and its model checker in the design phase of an asynchronous extension of SOAP, called aSOAP. For this purpose, we describe aSOAP as a set of communicating UML state machines, for which a semantics over doubly labelled transition systems has been provided.
A year-long quality improvement project on fluid management using blood volume monitoring during hemodialysis

Abstract Background: Inadequate removal of extracellular volume markedly increases blood pressure and contributes to high morbidity and mortality in hemodialysis patients. Advances in fluid management are needed to improve clinical outcomes. The aim of this quality improvement project was to examine the advantages of using a hematocrit-based, blood volume monitor (Crit-Line) for 12 months, as part of a clinic-wide, fluid management program in one dialysis facility. Methods: Forty-five individuals were receiving hemodialysis at one facility at project initiation and are included in this analysis. Monthly averaged clinical parameters (dialysis treatment information, blood pressures, blood volume, and laboratory data) were compared from Months 1–12. Analyses were conducted overall and according to the presence/absence of hypertension at Month 1 (Baseline). Antihypertensive medication changes were assessed for patients with hypertension at Month 1. Results: Average hemodialysis treatment time (+10.6 minutes, p = 0.002), eKt/V (+0.25, p < 0.001) and online clearance (+0.21, p < 0.0001) increased significantly in Month 12 versus Month 1. Average albumin levels and normalized protein catabolic rate increased from Month 1 to 12. Post-dialysis systolic blood pressure (SBP) decreased by Month 12 (p = 0.003). In hypertensive patients (SBP ≥ 140 mmHg in Month 1), there were significant differences in pre- and post-dialysis SBP between Month 1 and Month 12 (pre-hemodialysis: p = 0.02; post-hemodialysis: p = 0.0003), and antihypertensive medication use decreased in 29% of patients, while only 11% increased use. Treatment time in hypertensive patients increased by 15.4 minutes (p = 0.0005). Limitations: This was a single, clinic-wide, quality improvement project with no control group. All data analyzed were from existing clinical records, so only routinely measured clinical variables were available and missing data were possible. Conclusions: During this year-long fluid management quality improvement project, decreases in post-dialysis SBP and increases in adequacy and treatment time were observed. Patients with hypertension at Month 1 experienced reductions in pre-dialysis SBP and antihypertensive medications.
Psychology of the professional reliability of the physical education teacher: strategies and ways of its realization

162 2. Morgen ,V.G. (2009), Psychodiagnostics of abnormal conditions of the personality: educational and methodical guide, publishing house Novosibirsk humanities university, Novosibirsk. 3. Ed. Karelin A.A. (2002), Psychological tests, Vol. 2, publishing house “Vlados center”, Moscow. 4. Solodkov, A.S. (1992), Exhaustion and restoration problems in sports: Lecture, Lesgaft University, St. Petersburg. 5. Solodkov, A.S. (1988), Physiological bases of adaptation to physical loadings: Lecture, Lesgaft University, St. Petersburg. 6. Solodkov, A.S. , Levshin, I.V. and Mikhno, L.V. (2013), Physiology of sports: Medicobiological bases of training of young hockey players: study guide, Lesgaft University, St. Petersburg. 7. Solodkov, A.S. (1995), Physical efficiency of athletes: Lecture, Lesgaft University, St. Petersburg. 8. Solodkov A.S. Sologub E.B. (2001), Age physiology: study guide, Lesgaft University, St. Petersburg. 9. Ed. J. Weng Raizying (1980), Classification and cluster (under edition), publishing house “Mir”, Moscow. 10. Ed. Saygadak, D. I. (2001), The MMPI test the methodical management, publishing house “N.B. Kireev”, Minsk, Belarus. Контактная информация: krestovnikov.kaf@gmail.com
Reading Text Increases Binocular Disparity in Dyslexic Children

Children with developmental dyslexia show reading impairment compared to their peers, despite being matched on IQ, socio-economic background, and educational opportunities. The neurological and cognitive basis of dyslexia remains a highly debated topic. Proponents of the magnocellular theory, which postulates abnormalities in the M-stream of the visual pathway cause developmental dyslexia, claim that children with dyslexia have deficient binocular coordination, and this is the underlying cause of developmental dyslexia. We measured binocular coordination during reading and a non-linguistic scanning task in three participant groups: adults, typically developing children, and children with dyslexia. A significant increase in fixation disparity was observed for dyslexic children solely when reading. Our study casts serious doubts on the claims of the magnocellular theory. The exclusivity of increased fixation disparity in dyslexics during reading might be a result of the allocation of inadequate attentional and/or cognitive resources to the reading process, or suboptimal linguistic processing per se.
Efficiency of Iron-Based Oxy-Hydroxides in Removing Antimony from Groundwater to Levels below the Drinking Water Regulation Limits

This study evaluates the efficiency of iron-based oxy-hydroxides to remove antimony from groundwater to meet the requirements of drinking water regulations. Results obtained by batch adsorption experiments indicated that the qualified iron oxy-hydroxide (FeOOH), synthesized at pH 4 for maintaining a high positive charge density (2.5 mmol OH−/g) achieved a residual concentration of Sb(III) below the EU drinking water regulation limit of 5 μg/L by providing an adsorption capacity of 3.1 mg/g. This is more than twice greater compared either to similar commercial FeOOHs (GFH, Bayoxide) or to tetravalent manganese feroxyhyte (Fe-MnOOH) adsorbents. In contrast, all tested adsorbents failed to achieve a residual concentration below 5 μg/L for Sb(V). The higher efficiency of the qualified FeOOH was confirmed by rapid small-scale column tests, since an adsorption capacity of 3 mg Sb(III)/g was determined at a breakthrough concentration of 5 μg/L. However, it completely failed to achieve Sb(V) concentrations below 5 μg/L even at the beginning of the column experiments. The results of leaching tests classified the spent qualified FeOOH to inert wastes. Considering the rapid kinetics of this process (i.e., 85% of total removal was performed within 10 min), the developed qualified adsorbent may be promoted as a prospective material for point-of-use Sb(III) removal from water in vulnerable communities, since the adsorbent’s cost was estimated to be close to 30 ± 3.4 €/103 m3 for every 10 μg Sb(III)/L removed.
Solution for secure private data storage in a cloud

Cloud computing and, more particularly, cloud databases, is a great technology for remote centralized data managing. However, there are some drawbacks including privacy issues, insider threats and potential database thefts. Full encryption of remote database does solve the problem, but disables many operations that can be held on DBMS side; therefore problem requires much more complex solution and specific encryptions. In this paper, we propose a solution for secure private data storage that protects confidentiality of user's data, stored in cloud. Solution uses order preserving and homomorphic proprietary developed encryptions. Proposed approach includes analysis of user's SQL queries, encryption of vulnerable data and decryption of data selection, returned from DBMS. We have validated our approach through the implementation of SQL queries and DBMS replies processor, which will be discussed in this paper. Secure cloud database architecture and used encryptions also will be covered.
Asymptotic analysis of the infinite-server queueing system with high-rate semi-Markov arrivals

Analysis of the infinite-server queueing system with semi-Markov arrivals is presented in the paper. The analysis is performed under an asymptotic condition of input rate infinite growth. It is shown that the stationary probability distribution of the number of customers in the system can be approximated by Gaussian distribution when the input rate is great enough. Parameters of the approximation are obtained in the paper. Presented numerical results validate an applicability of the obtained approximation.
Differences in miRNA and mRNA Profile of Papillary Thyroid Cancer Variants

Papillary thyroid cancer (PTC) can be divided into classical variant of PTC (cPTC), follicular variant of PTC (fvPTC), and tall cell variant (tcPTC). These variants differ in their histopathology and cytology; however, their molecular background is not clearly understood. Our results shed some new light on papillary thyroid cancer biology as new direct miRNA-gene regulations are discovered. The Cancer Genome Atlas (TCGA) 466 thyroid cancer samples were studied in parallel datasets to discover potential miRNA-mRNA regulations. Additionally, miRNAs and genes differentiating PTC variants (cPTC, fvPTC, and tcPTC) were indicated. Putative miRNA regulatory pairs were discovered: hsa-miR-146b-5p with PHKB and IRAK1, hsa-miR-874-3p with ITGB4 characteristic for classic PTC samples, and hsa-miR-152-3p with TGFA characteristic for follicular variant PTC samples. MiRNA-mRNA regulations discovery opens a new perspective in understanding of PTC biology. Furthermore, our successful pipeline of miRNA-mRNA regulatory pathways discovery could serve as a universal tool to find new miRNA-mRNA regulations, also in different datasets.
A Uniform Representation of Single-and Multistage Interconnection Networks Used in SIMD Machines

A switching theoretic framework for the study of interconnection networks is developed. An equivalence relationship between networks is defined. Single-stage and multistage networks that are particularly useful for single-instruction multiple-data stream (SIMD) machines are studied. It is shown that the networks form two distinct equivalence classes under this definition of equivalence relationship. It is shown that any multistage network can be easily modified to realize the permutations that are admissible by any other network which is equivalent to it.
Quantitative gait markers and incident fall risk in older adults.

BACKGROUND Identifying quantitative gait markers of falls in older adults may improve diagnostic assessments and suggest novel intervention targets. METHODS We studied 597 adults aged 70 and older (mean age 80.5 years, 62% women) enrolled in an aging study who received quantitative gait assessments at baseline. Association of speed and six other gait markers (cadence, stride length, swing, double support, stride length variability, and swing time variability) with incident fall rate was studied using generalized estimation equation procedures adjusted for age, sex, education, falls, chronic illnesses, medications, cognition, disability as well as traditional clinical tests of gait and balance. RESULTS Over a mean follow-up period of 20 months, 226 (38%) of the 597 participants fell. Mean fall rate was 0.44 per person-year. Slower gait speed (risk ratio [RR] per 10 cm/s decrease 1.069, 95% confidence interval [CI] 1.001-1.142) was associated with higher risk of falls in the fully adjusted models. Among six other markers, worse performance on swing (RR 1.406, 95% CI 1.027-1.926), double-support phase (RR 1.165, 95% CI 1.026-1.321), swing time variability (RR 1.007, 95% CI 1.004-1.010), and stride length variability (RR 1.076, 95% CI 1.030-1.111) predicted fall risk. The associations remained significant even after accounting for cognitive impairment and disability. CONCLUSIONS Quantitative gait markers are independent predictors of falls in older adults. Gait speed and other markers, especially variability, should be further studied to improve current fall risk assessments and to develop new interventions.