Miracle-dz/UniFAR-FTUs huggingface dataset:
Cardiac Complications in Acute Ischemic Stroke

Introduction To characterize cardiac complications in acute ischemic stroke (AIS) patients admitted from an urban emergency department (ED). Methods Retrospective cross-sectional study evaluating AIS patients admitted from the ED within 24 hours of symptom onset who also had an echocardiogram performed within 72 hours of admission. Results Two hundred AIS patients were identified with an overall in-hospital mortality rate of 8% (n = 16). In our cohort, 57 (28.5%) of 200 had an ejection fraction less than 50%, 35 (20.4%) of 171 had ischemic changes on electrocardiogram (ECG), 18 (10.5%) of 171 presented in active atrial fibrillation, 21 (13.0%) of 161 had serum troponin elevation, and 2 (1.1%) of 184 survivors had potentially lethal arrhythmias on telemetry monitoring. Subgroup analysis revealed higher in-hospital mortality rates among those with systolic dysfunction (15.8% versus 4.9%; P = 0.0180), troponin elevation (38.1% versus 3.4%; P < 0.0001), atrial fibrillation on ECG (33.3% versus 3.8%; P = 0.0003), and ischemic changes on ECG (17.1% versus 6.1%; P = 0.0398) compared with those without. Conclusion A proportion of AIS patients may have cardiac complications. Systolic dysfunction, troponin elevation, atrial fibrillation, or ischemic changes on ECG may be associated with higher in-hospital mortality rates. These findings support the adjunctive role of cardiac-monitoring strategies in the acute presentation of AIS.
A Viterbi-like algorithm and EM learning for statistical abduction

We propose statistical abduction as a rstorder logical framework for representing and learning probabilistic knowledge. It combines logical abduction with a parameterized distribution over abducibles. We show that probability computation, a Viterbilike algorithm and EM learning for statistical abduction achieve the same eÆciency as specilzed algorithms for HMMs (hidden Markov models), PCFGs (probabilistic context-free grammars) and sc-BNs (singly connetcted Bayesian networks).
Locality of Reference, Patterns in Program Behavior, Memory Management, and Memory Hierarchies | Very Rough, Partial, Incompletely-baked Draft. Do Not Redistribute (comments Welcome.)

Locality of reference is crucial to the performance of modern computers, but is actually poorly understood. In this paper, we survey issues in locality and memory hierarchy design, attempting to bring together what is known, correct common misconceptions, and clarify what is not known. We present a uniied approach to locality, based on the concept of timescale relativity, which simply says that some patterns in program behavior are relevant to issues of caching, and others are not, and that the diierence depends crucially on the timescale relevant to a particular cache. Memory hierarchies use a kind of online, adaptive algorithm to control caching; such algorithms cannot be studied properly without some understanding of the regularities in the \data" (program behavior) they must process. We attempt a vertical uniication, showing that locality of reference results from regularities in the structure of programs, and from regularities in how memory allocators map program objects onto virtual address space.
Infinite Deformed Groups and Their Geometrical and Physical Applications

In this article we give the realization of the Klein's Program for geometrical structures (Riemannian spaces and fiber bundles with connection) with arbitrary variable curvature within the framework of infinite deformed groups. These groups generalize gauge groups to the case of nontrivial action on the base space of bundles with use of idea of groups deformations. We also show that infinite deformed groups give a group-theoretic description of gauge fields (gravitational field with its metric or vierbein part similarly to gauge fields of internal symmetry) which is alternative for their geometrical interpretation.
Formally Composing Components in Product Line Context

Components composition is core techniques of software product line, which can promote reuse of components. Variability exists in components and components composition in SPL context, which bring new challenges to tradition components composition techniques. vADL can formally describes SPL architectures, and also supports layered components compositions. The paper provides systemic methods for components compositions with vADL. Techniques of variability points binding, constrains assembly, guard condition restrict are presented in detail, which can assemble variability of components. Behavior assembly technique also be described, which utilize parallel combined mechanism of n-calculus. Variability in structure assembly, ports assembly and behavior assembly also is discussed. In order to sure correctness and consistency, some analysis methods for components composition also are provided.
pong: fast analysis and visualization of latent clusters in population genetic data

1 Motivation A series of methods in population genetics use multilocus genotype data to assign individuals membership in latent clusters. These methods belong to a broad class of mixed-membership models, such as latent Dirichlet allocation used to analyze text corpora. Inference from mixed-membership models can produce different output matrices when repeatedly applied to the same inputs, and the number of latent clusters is a parameter that is often varied in the analysis pipeline. For these reasons, quantifying, visualizing, and annotating the output from mixed-membership models are bottlenecks for investigators across multiple disciplines from ecology to text data mining. 2 Results We introduce pong, a network-graphical approach for analyzing and visualizing membership in latent clusters with a native D3.js interactive visualization. pong leverages efficient algorithms for solving the Assignment Problem to dramatically reduce runtime while increasing accuracy compared to other methods that process output from mixed-membership models. We apply pong to 225,705 unlinked genome-wide single-nucleotide variants from 2,426 unrelated individuals in the 1000 Genomes Project, and identify previously overlooked aspects of global human population structure. We show that pong outpaces current solutions by more than an order of magnitude in runtime while providing a customizable and interactive visualization of population structure that is more accurate than those produced by current tools. 3 Availability pong is freely available and can be installed using the Python package management system pip. pong’s source code is available at https://github.com/abehr/pong. 4 Contact aaron_behr@alumni.brown.edu, sramachandran@brown.edu
Factored Sampling for Hierarchical Monitoring of Complex Hybrid Systems

A method of making polymer polyols is disclosed wherein a relatively low molecular weight liquid polymer of an ethylenically unsaturated monomer is mixed with a polyol and crosslinked in the polyol. The relatively low molecular weight polymer which is mixed in the polyol may have a variety of microstructures since the low molecular weight polymer was prepared separate from the polyol.
Neoliberal Biopolitics through the Spectacles of the Gene

Who or what is the subject of the gene, and where might we locate the ethical and political agency of genetic subjects? This is not just a matter of me myself as the object of genetic ‘causality’ or agent of rational choice. The gene and its cultural rhetorics of risk and redemption increasingly frame the ways that I am incited to intervene into my life, to mitigate my risks, to heal my illnesses, to correct my deviance, to eradicate or to enhance, and to understand who and what I am, at last, with the purported certainty of science. Gay genes, Jewish genes, cancer genes, genes for disease, for intelligence, for intergenerational trauma or alcoholism. The list is virtually limitless. For every human social enigma, it seems, there is a genetic solution—or the spectacular promise of one—just around the corner. Deborah Lynn Steinberg’s Genes and the Bioimaginary critically responds to the infectious and oftentimes cruel phantasies purchased on and promulgated by ‘the gene’—that dominant trope permeating our popular episteme, figure of cultural mythology and everyday commonsense. Steinberg visits an array of familiar sites where the gene is at work in—and as—the interplay of neoliberal state science, mediatised spectacle, and popular culture. ‘The socio-cultural, biopolitical and bioethical dimensions of genes’, she argues, ‘articulate with the power of spectacle and projection and the cultural negotiations that constitute genetic capital’ (p. 4). Science as Culture, 2017 Vol. 26, No. 2, 255–259, http://dx.doi. org/10.1080/09505431.2016. 1238890
PENGARUH PENGGUNAAN STRATEGI TRUE OR FALSE TERHADAP HASIL BELAJAR SISWA KELAS IV PADA MATERI PERUBAHAN KENAMPAKAN BUMI DAN BENDA LANGIT

Penelitian ini bertujuan untuk mengetahui peningkatan hasil belajar sains peserta didik pada materi perubahan kenampakan bumi dan benda langit dengan menggunakan strategi true or false dan menggunakan pembelajaran secara konvensional serta pembelajaran mana yang lebih baik antara pembelajaran dengan strategi true or false atau pembelajaran konvensional. Penelitian ini menggunakan metode eksperimen dengan desain kelompok pretes-postes. Penelitian ini dilakukan di SDN Karangpawulang dan SDN Cilimbangan. Berdasarkan penelitian yang telah dilakukan oleh peneliti, ditunjukkan bahwa pembelajaran dengan menggunakan strategi true or false maupun pembelajaran secara konvensional dapat meningkatkan hasil belajar sains. Walaupun kedua pembelajaran menunjukkan peningkatan tetapi pembelajaran menggunakan strategi true or false lebih baik dalam meningkatkan hasil belajar sains. Hal ini terbukti dari hasil perhitungan uji perbedaan rata-rata data postes pada kelompok eksperimen dan kelompok kontrol dengan nilai 0,000 yang berarti terdapat perbedaan rata-rata hasil belajar sains peserta didik pada kedua kelompok. Kata kunci : strategi true or false, hasil belajar sains.
More genes underwent positive selection in chimpanzee evolution than in human evolution

Observations of numerous dramatic and presumably adaptive phenotypic modifications during human evolution prompt the common belief that more genes have undergone positive Darwinian selection in the human lineage than in the chimpanzee lineage since their evolutionary divergence 6–7 million years ago. Here, we test this hypothesis by analyzing nearly 14,000 genes of humans and chimps. To ensure an accurate and unbiased comparison, we select a proper outgroup, avoid sequencing errors, and verify statistical methods. Our results show that the number of positively selected genes is substantially smaller in humans than in chimps, despite a generally higher nonsynonymous substitution rate in humans. These observations are explainable by the reduced efficacy of natural selection in humans because of their smaller long-term effective population size but refute the anthropocentric view that a grand enhancement in Darwinian selection underlies human origins. Although human and chimp positively selected genes have different molecular functions and participate in different biological processes, the differences do not ostensibly correspond to the widely assumed adaptations of these species, suggesting how little is currently known about which traits have been under positive selection. Our analysis of the identified positively selected genes lends support to the association between human Mendelian diseases and past adaptations but provides no evidence for either the chromosomal speciation hypothesis or the widespread brain-gene acceleration hypothesis of human origins.
Paauglių emocinis intelektas: psichosocialinių sunkumų, stresinių gyvenimo įvykių bei demografinių charakteristikų analizė

Tyrimo tikslas – nustatyti bei analizuoti emocinio intelekto ir socialinės kompetencijos, emocinių/ elgesio sunkumų, stresinių gyvenimo įvykių bei demografinių charakteristikų sąsajas. Tyrime dalyvavo 178, 12–18 metų paaugliai: 90 merginų ir 88 vaikinai. Tyrime buvo naudojama BarOn EQ – i: Jaunimo versija (EQ – i:YV), R. BarOn ir J.D. A. Parker, 2000), Jaunuolių elgesio skalė (YSR), T.M. Achenbach, 1991), Stresinių gyvenimo įvykių sąvadas (SGĮS), sud. R. Pukinskaitė, 2008), socialinės kompetencijos ir demografinių rodiklių anketa. Tyrimo rezultatai parodė, kad aukstesnio bendro emocinio intelekto (EQ) paaugliai turi statistiskai reiksmingai mažiau internalių, eksternalių ir bendrų emocinių bei elgesio sunkumų: jų žemesni užsiskleidimo/ depresiskumo, somatinių skundų, socialinių sunkumų, delinkventinio elgesio rodikliai. Eksternalios, internalios ir bendras sunkumų lygis neigiamai statistiskai reiksmingai siejasi su tarpasmeninių santykių, adaptyvumo bei vyraujancios nuotaikos gebėjimais. Aukstesnio emocinio intelekto paaugliams būdingi aukstesni mokymosi laimėjimai, jų geresni santykiai su bendraamžiais, turi daugiau laisvalaikio pomėgių (jie yra socialiai aktyvesni): mokymosi rezultatai bei laisvalaikio pomėgiai/ užsiėmimai reiksmingai koreliuoja su asmens vidiniais, tarpasmeninių santykių ir adaptyvumo skalių įverciais. Optimistiskesnių ir laimingesnių paauglių santykiai su bendraamžiais yra geresni. Daugiau stresinių gyvenimo įvykių patyrusiems paaugliams būdingi geresni streso valdymo gebėjimai, taciau jų prastesni tarpasmeniniai santykiai su bendraamžiais, neigiamesnė vyraujanti nuotaika. Nustatyta, kad merginų bendras emocinis intelektas (EQ) yra aukstesnis nei vaikinų. Rajoniniuose miestuose gyvenancių paauglių EQ rodikliai yra aukstesni nei gyvenancių kaimuose; paauglių, gyvenancių su globėjais arba globos namuose tarpasmeninių santykių, adaptyvumo gebėjimai yra žemesni, negu paauglių, gyvenancių su abiem biologiniais tėvais. Paauglių, kurių tėvai turi nebaigtą vidurinį ar vidurinį issilavinimą tarpasmeninių santykių, adaptyvumo gebėjimai yra žemesni, negu paauglių, kurių tėvų issilavinimas yra aukstesnysis. Didesnes pajamas gaunanciose seimose augantys paaugliai yra aukstesnio emocinio intelekto.
MCs detection approach using Bagging and Boosting based twin support vector machine

In this paper we discuss a new approach for the detection of clustered microcalcifications (MCs) in mammograms. MCs are an important early sign of breast cancer in women. Their accurate detection is a key issue in computer aided detection scheme. To improve the performance of detection, we propose a Bagging and Boosting based twin support vector machine (BB-TWSVM) to detect MCs. The algorithm is composed of three modules: the image pro-processing, the feature extraction component and the BB-TWSVM module. The ground truth of MCs in mammograms is assumed to be known as a priori. First each MCs is preprocessed by using a simple artifact removal filter and a well designed high-pass filter. Then the combined image feature extractors are employed to extract 164 image features. In the combined image features space, the MCs detection procedure is formulated as a supervised learning and classification problem, and the trained BB-TWSVM is used as a classifier to make decision for the presence of MCs or not. The experimental results of this study indicate the potential of the approach for computer-aided detection of breast cancer.
CAGE Basic/Analysis Databases: the CAGE resource for comprehensive promoter analysis

Cap-analysis gene expression (CAGE) Basic and Analysis Databases store an original resource produced by CAGE, which measures expression levels of transcription starting sites by sequencing large amounts of transcript 5′ ends, termed CAGE tags. Millions of human and mouse high-quality CAGE tags derived from different conditions in >20 tissues consisting of >250 RNA samples are essential for identification of novel promoters and promoter characterization in the aspect of expression profile. CAGE Basic Database is a primary database of the CAGE resource, RNA samples, CAGE libraries, CAGE clone and tag sequences and so on. CAGE Analysis Database stores promoter related information, such as counts of related transcripts, CpG islands and conserved genome region. It also provides expression profiles at base pair and promoter levels. Both databases are based on the same framework, CAGE tag starting sites, tag clusters for defining promoters and transcriptional units (TUs). Their associations and TU attributes are available to find promoters of interest. These databases were provided for Functional Annotation Of Mouse 3 (FANTOM3), an international collaboration research project focusing on expanding the transcriptome and subsequent analyses. Now access is free for all users through the World Wide Web at .
Microprocessor based voice recognition system realization

Voice recognition systems, which today is one of gradually started to gain importance. In this study, using a PIC18F452 microcontroller, two registered words, compared with a voice command input. Registered with the sound of the word overlap as a result of the exit sign is active. Recognition of the audio signals zero crossing for the count and time was examined. In general, the voice recognition process, sound recording and determination of the expression; processing of sound, making comparison and integration of rest; finally, the expression was created with the realization of the corresponding functions. Developed in this system, without sounds recording of audio signal processing are performed simultaneously. In this system, not a waste of time for this situation may be many advantages to the system. Work is relatively simple and economically cheap.
Examining the Usability of Web Site Search

One of the most pressing usability issues in the design of web sites is that of how to improve navigation and search. We are conducting a series of usability studies to address this problem, focusing on web sites that consist of large collections of loosely organized information. This article describes our method and presents preliminary results which suggest that use of faceted metadata can be useful both for the initial stages of highly constrained search and for the intermediate stages of less constrained browsing tasks. We also find that users state an interest in using different search interface types to support different search strategies.
Experiments on Visual Information Extraction with the Faces of Wikipedia

We present a series of visual information extraction experiments using the Faces of Wikipedia database - a new resource that we release into the public domain for both recognition and extraction research containing over 50,000 identities and 60,000 disambiguated images of faces. We compare different techniques for automatically extracting the faces corresponding to the subject of a Wikipedia biography within the images appearing on the page. Our top performing approach is based on probabilistic graphical models and uses the text of Wikipedia pages, similarities of faces as well as various other features of the document, meta-data and image files. Our method resolves the problem jointly for all detected faces on a page. While our experiments focus on extracting faces from Wikipedia biographies, our approach is easily adapted to other types of documents and multiple documents. We focus on Wikipedia because the content is a Creative Commons resource and we provide our database to the community including registered faces, hand labeled and automated disambiguations, processed captions, meta data and evaluation protocols. Our best probabilistic extraction pipeline yields an expected average accuracy of 77\% compared to image only and text only baselines which yield 63\% and 66\% respectively.
Temperature-Dependent Sex Determination in Fish Revisited: Prevalence, a Single Sex Ratio Response Pattern, and Possible Effects of Climate Change

Background In gonochoristic vertebrates, sex determination mechanisms can be classified as genotypic (GSD) or temperature-dependent (TSD). Some cases of TSD in fish have been questioned, but the prevalent view is that TSD is very common in this group of animals, with three different response patterns to temperature. Methodology/Principal Findings We analyzed field and laboratory data for the 59 fish species where TSD has been explicitly or implicitly claimed so far. For each species, we compiled data on the presence or absence of sex chromosomes and determined if the sex ratio response was obtained within temperatures that the species experiences in the wild. If so, we studied whether this response was statistically significant. We found evidence that many cases of observed sex ratio shifts in response to temperature reveal thermal alterations of an otherwise predominately GSD mechanism rather than the presence of TSD. We also show that in those fish species that actually have TSD, sex ratio response to increasing temperatures invariably results in highly male-biased sex ratios, and that even small changes of just 1–2°C can significantly alter the sex ratio from 1∶1 (males∶females) up to 3∶1 in both freshwater and marine species. Conclusions/Significance We demonstrate that TSD in fish is far less widespread than currently believed, suggesting that TSD is clearly the exception in fish sex determination. Further, species with TSD exhibit only one general sex ratio response pattern to temperature. However, the viability of some fish populations with TSD can be compromised through alterations in their sex ratios as a response to temperature fluctuations of the magnitude predicted by climate change.
Three-dimentional tracking of human eye

The study of human movements is the object of numerous searches, among them, the study of the face movements and more particularly the eye kinetics estimate represents an important part. A study realized by artificial vision is presented here. It allows to characterize eye movements in normal shooting condition (mobility of the subject, background lighting). Our approach allows to obtain in a simple way the localization of the iris and the characterization of their movement in the three dimensional shape. The absolute 3D movement of eyeballs and their relative movement with regard to the head are obtained, even if this one are moving.
GSK-3: new thoughts on an old enzyme.

Over the past decade, a serine–threonine kinase first characterized for its role in glycogen metabolism has shown itself to be a key player in numerous processes, in organisms ranging from yeast to mammals (reviewed in Yost et l., 1997). Glycogen synthase kinase-3 was originally idenified as a constitutively active kinase that is inactivated in esponse to extracellular signals. However, it is now clear hat extracellular signals can also activate GSK-3 to direct evelopmental patterning and that GSK-3’s function is ediated both by phosphorylation and by its interaction ith activating and inhibitory binding partners. In this eview we focus on three organisms that highlight the aried roles that GSK-3 plays in embryonic development, enopus, sea urchin, and Dictyostelium, and discuss the molecular mechanisms that regulate GSK-3 activity in each species.