Miracle-dz/UniFAR-FTUs huggingface dataset:
Interprofessional care review with medical residents: Lessons learned, tensions aired – A pilot study

Integrated interprofessional care teams are the focus of Canadian and American recommendations about the future of health care. Keeping with this, a family medicine teaching site developed an educational initiative to expose trainees to interprofessional care processes and learning (Interprofessional Care Review; IPC). A formative evaluation pilot study was completed using one-on-one interviews and a focus group (n = 6) with family medicine residents. A semi-structured guide was utilized regarding: knowledge, skills and attitudes related to interprofessional care; their experience of the processes utilized in IPC. Data were analyzed using content analysis. Residents' perspectives on their learning revolved around four themes: changes to understanding and practice of interprofessional care; personal impact of IPC; learning about other health professionals; tension and challenges of IPC learning and clinical implementation. Residents valued the educational experience, but identified that faculty supervisors provided “mixed messages” in the value of collaborating with other health professionals. Implications regarding future educational and research opportunities are discussed.
Realization of RRO-NRDPWT-based ECG signal compression with modified run-length coding

With high compression performance, realization of wavelet-based data compression system is significant for multi-lead ECG signal recording. In this paper, we proposed a modified run-length coding (MRLC) algorithm associated with an efficient quantization scheme for the realization of a RRO-NRDPWT-based ECG data compression system. The MRLC has the characteristics of regularity and low computational complexity which make it a suitable for hardware implementation at a cost of compression performance. This compromise will be compensated by the new quantization scheme. By using the MIT-BIH arrhythmia database, the experimental results show that the proposed scheme can be competitive comparing to other wavelet-based approaches in compression performance. In addition, the MRLC can improve traditional run-length coding by about 13%.
Nominal Henkin Semantics: simply-typed lambda-calculus models in nominal sets

We investigate a class of nominal algebraic Henkin-style models for the simply typed lambda-calculus in which variables map to names in the denotation and lambda-abstraction maps to a (non-functional) name-abstraction operation. The resulting denotations are smaller and better-behaved, in ways we make precise, than functional valuation-based models. Using these new models, we then develop a generalisation of \lambda-term syntax enriching them with existential meta-variables, thus yielding a theory of incomplete functions. This incompleteness is orthogonal to the usual notion of incompleteness given by function abstraction and application, and corresponds to holes and incomplete objects.
Capturing Skeleton-based Animation Data from a Video

This paper presents a semi-automatic method to capture animation data from a single camera video. The video is first segmented and analyzed, and a 3D character model with skeleton rigged is input as a reference model. Then, the user modifies the reference model to fit the subject’s contour in the starting frame, and specifies the body and limbs contours of the subject character. Our system then reconstructs the motion by estimating the reference model’s pose automatically in each frame forward. Finally, the user’s intervention helps to refine the result. This paper shows a better motion reconstruction result than totally automatic methods that are widely used in video-based motion capture in computer vision.
MIMO Gaussian Channels With Arbitrary Inputs: Optimal Precoding and Power Allocation

In this paper, we investigate the linear precoding and power allocation policies that maximize the mutual information for general multiple-input-multiple-output (MIMO) Gaussian channels with arbitrary input distributions, by capitalizing on the relationship between mutual information and minimum mean-square error (MMSE). The optimal linear precoder satisfies a fixed-point equation as a function of the channel and the input constellation. For non-Gaussian inputs, a nondiagonal precoding matrix in general increases the information transmission rate, even for parallel noninteracting channels. Whenever precoding is precluded, the optimal power allocation policy also satisfies a fixed-point equation; we put forth a generalization of the mercury/waterfilling algorithm, previously proposed for parallel noninterfering channels, in which the mercury level accounts not only for the non-Gaussian input distributions, but also for the interference among inputs.
An efficient decision rule-based system for the protein residue-residue contact prediction

Protein structure prediction remains one of the most important challenges in molecular biology. Contact maps have been extensively used as a simplified representation of protein structures. In this work, we propose a multi-objective evolutionary approach for contact map prediction. The proposed method bases the prediction on a set of physico-chemical properties and structural features of the amino acids, as well as evolutionary information in the form of an amino acid position specific scoring matrix (PSSM). The proposed technique produces a set of decision rules that identify contacts between amino acids. Results obtained by our approach are presented and confirm the validity of our proposal.
Returns to growth in a nonparametric DEA approach

In this contribution, first the concept of returns to growth (RTG) of a high-tech firm facing hyper-competition in the new economy is introduced by describing a proportional relationship between growth in inputs and growth in outputs using the growth efficiency (GE) model of Sengupta. Second, both technology- and value-based methods are suggested for estimating the RTG behavior of high-tech firms. Third, although the GE concept seems closely related to the notion of total factor productivity change, this link remains unexplored: we suggest a link between both concepts. Finally, our empirical application to the Indian computer industry reveals that first, companies operating under increasing returns to scale (RTS) may exhibit constant or decreasing RTG; second, companies showing constant RTS may exhibit increasing or decreasing RTG; and third, companies showing decreasing RTS may exhibit constant or increasing RTG. These findings imply that RTS estimates need not provide proper information regarding the growth strategy behavior of high-tech companies.
Activated platelets are the source of elevated levels of soluble CD40 ligand in the circulation of inflammatory bowel disease patients

Background: The CD40/CD40L system, a key regulator and amplifier of immune reactivity, is activated in inflammatory bowel disease (IBD) mucosa. Aims: To determine whether plasma levels of sCD40L are elevated in Crohn’s disease (CD) and ulcerative colitis (UC) patients compared with normal controls, to investigate the cellular source of sCD40L, and to explore CD40L induction mechanisms. Patients: CD, UC, and normal control subjects were studied. Methods: The concentration of sCD40L in plasma and supernatants of freshly isolated platelets and autologous peripheral blood T cells (PBT) was measured by ELISA. Surface CD40L expression level was measured by flow cytometry in resting and thrombin activated platelets, and unstimulated and CD3/CD28 stimulated PBT before and after coculture with human intestinal microvascular endothelial cells (HIMEC). Results: Compared with normal controls, plasma sCD40L levels were significantly higher in both CD and UC patients and proportional to the extent of mucosal inflammation. Platelets from IBD patients displayed a significantly higher surface CD40L expression than those from control subjects, and released greater amounts of sCD40L than autologous PBT. Contact with IL-1β activated HIMEC induced significant upregulation of CD40L surface expression and release by platelets. Conclusions: Elevated levels of sCD40L in the circulation of IBD patients reflect enhanced surface expression and release of CD40L by platelets. This phenomenon translates to an increased platelet activation state apparently induced by passage through an inflamed mucosal microvascular bed, a conclusion supported by the positive correlation of plasma sCD40L levels with the extent of anatomical involvement by IBD. These results suggest that platelet-endothelial interactions critically contribute to activation of the CD40 pathway in IBD.
Replicative Senescence of Mesenchymal Stem Cells: A Continuous and Organized Process

Mesenchymal stem cells (MSC) comprise a promising tool for cellular therapy. These cells are usually culture expanded prior to their application. However, a precise molecular definition of MSC and the sequel of long-term in vitro culture are yet unknown. In this study, we have addressed the impact of replicative senescence on human MSC preparations. Within 43 to 77 days of cultivation (7 to 12 passages), MSC demonstrated morphological abnormalities, enlargement, attenuated expression of specific surface markers, and ultimately proliferation arrest. Adipogenic differentiation potential decreased whereas the propensity for osteogenic differentiation increased. mRNA expression profiling revealed a consistent pattern of alterations in the global gene expression signature of MSC at different passages. These changes are not restricted to later passages, but are continuously acquired with increasing passages. Genes involved in cell cycle, DNA replication and DNA repair are significantly down-regulated in late passages. Genes from chromosome 4q21 were over-represented among differentially regulated transcripts. Differential expression of 10 genes has been verified in independent donor samples as well as in MSC that were isolated under different culture conditions. Furthermore, miRNA expression profiling revealed an up-regulation of hsa-mir-371, hsa-mir-369-5P, hsa-mir-29c, hsa-mir-499 and hsa-let-7f upon in vitro propagation. Our studies indicate that replicative senescence of MSC preparations is a continuous process starting from the first passage onwards. This process includes far reaching alterations in phenotype, differentiation potential, global gene expression patterns, and miRNA profiles that need to be considered for therapeutic application of MSC preparations.
Photo LOI: browsing multi-user photo collections

The number of digital photographs is growing beyond the abilities of individuals to easily manage and understand their own photo collections. Photo LOI (Level of Interest) is a technique that filters, aggregates, and visualizes photographs taken by multiple users who shared temporal, spatial, and/or social context at the point of photo capture. Photo LOI enables groups of photographers to see and manipulate visualizations of their photographic activities over time and social space in order to help cluster and select photos, and enables researchers to study contextual patterns in the phototaking habits of different users and groups of users. In this paper we give a brief overview of Photo LOI's features and describe some of its applications.
The surface electromyography biofeedback in pain management - theoretical assumptions and possibilities of using the method

Psychophysiological assessments and biofeedback based interventions for disorders whose main symptom of interest is chronic pain can be highly effective and useful in the clinical environment. The evidence supporting the effectiveness of psychophysiological assessments and interventions for phantom limb pain, upper and lower back pain, non-cardiac chest pain, and pelvic floor pain disorders is reviewed to provide examples of how these techniques are applied to problems having differing etiologies. Streszczenie. Zastosowanie elektromiograficznej metody biofeedback w leczeniu bolu moze byc bardzo przydatne w warunkach klinicznych. Dowody skuteczności metod opartych o trening funkcji psychofizjologicznych, w leczeniu bolu fantomowego, w obrebie konczyn gornych, dolnej cześci plecow, nie-sercowego bolu w klatce piersiowej oraz dolegliwści bolowych w obrebie miednicy mniejszej wymagają dalszych obserwacji klinicznych w celu ich szerszego zastosowania w leczenia bolu o roznej etiologii (Metoda biofeedback elektromiografii powierzchniowej w leczeniu bolu zalozenia teoretyczne i mozliwości zastosowania).
The Paranoid Optimist: An Integrative Evolutionary Model of Cognitive Biases

Human cognition is often biased, from judgments of the time of impact of approaching objects all the way through to estimations of social outcomes in the future. We propose these effects and a host of others may all be understood from an evolutionary psychological perspective. In this article, we elaborate error management theory (EMT; Haselton & Buss, 2000). EMT predicts that if judgments are made under uncertainty, and the costs of false positive and false negative errors have been asymmetric over evolutionary history, selection should have favored a bias toward making the least costly error. This perspective integrates a diverse array of effects under a single explanatory umbrella, and it yields new content-specific predictions.
Another Outlier Bites the Dust: Computing Meaningful Aggregates in Sensor Networks

Recent work has demonstrated that readings provided by commodity sensor nodes are often of poor quality. In order to provide a valuable sensory infrastructure for monitoring applications, we first need to devise techniques that can withstand "dirty" and unreliable data during query processing. In this paper we present a novel aggregation framework that detects suspicious measurements by outlier nodes and refrains from incorporating such measurements in the computed aggregate values. We consider different definitions of an outlier node, based on the notion of a user-specified minimum support, and discuss techniques for properly routing messages in the networkin order to reduce the bandwidth consumption and the energy drain during the query evaluation. In our experiments using real and synthetic traces we demonstrate that: (i) a straightforward evaluation of a user aggregate query leads to practically meaningless results due to the existence of outliers; (ii) our techniques can detect and eliminate spurious readings without any application specific knowledge of what constitutes normal behavior; (iii) the identification of outliers, when performed inside the network, significantly reduces bandwidth and energy drain compared to alternative methods that centrally collect and analyze all sensory data; and (iv) we can significantly reduce the cost of the aggregation process by utilizing simple statistics on outlier nodes and reorganizing accordingly the collection tree.
The evolution of morphology, crystallization and static and dynamic mechanical properties of long glass-fibre–reinforced polypropylene composites under thermo-oxidative ageing

In this work, the static and dynamic mechanical properties, crystallization behaviours, and morphology of long glass-fibre–reinforced polypropylene (PP) composites with thermo-oxidative ageing time from 0 day to 50 days at 120°C were investigated and discussed. The static mechanical properties showed a global decrease in tensile, bending and impact strengths with increasing ageing time. From the results obtained by scanning electronic microscopic observations, interface debonding clearly occurred between the glass fibre and PP matrix in the aged samples. The crystallinity (X c) of the composites was analyzed by differential scanning calorimetry; annealing process played the leading role in the early period of ageing, while as ageing progressed, the degradation of PP matrix dominated the ageing process and X c decreased. The dynamic mechanical analysis results indicated that the storage modulus and glass transition temperature of the composites also decreased with prolonging ageing time. Then, the apparent activation energy (E) of glass transition was calculated by the Arrhenius equation with different scanning frequencies. A higher value of E was obtained for the samples in the later ageing period, which means a higher energy barrier for glass transition.
No difference in risk for thrombocytopenia during treatment of pulmonary embolism and deep venous thrombosis with either low-molecular-weight heparin or unfractionated heparin: a metaanalysis.

BACKGROUND Low-molecular-weight heparin (LMWH) is a popular alternative to unfractionated heparin (UH) for the treatment of pulmonary embolism (PE) and deep vein thrombosis (DVT), in part based on the perception of a lower risk for heparin-induced thrombocytopenia (HIT). To investigate the evidence supporting this perception, we performed a metaanalysis to compare the incidence of thrombocytopenia between LMWH and UH during PE and/or DVT treatment. METHODS Randomized trials comparing LMWH with UH for PE and/or DVT treatment were searched for in the MEDLINE database, bibliographies, and by correspondence with published investigators. Two reviewers independently selected high-quality studies and extracted data regarding heparin-associated thrombocytopenia (HAT), HIT confirmed by laboratory testing, and heparin-induced thrombocytopenia with thrombosis (HITT). Outcome rates between LMWH and UH were compared using a binomial, generalized linear mixed model with a logit link and Gaussian random effects for study. RESULTS Thirteen studies involving 5,275 patients met inclusion criteria. There were no statistically significant differences in HAT rates between the two treatments (LMWH, 1.2%; UH, 1.5%; p = 0.246). The incidence of documented HIT and HITT was too low to make an adequate comparison between groups. CONCLUSIONS Our review disclosed no statistically significant difference in HAT between LMWH and UH and insufficient evidence to conclude that HIT and HITT rates were different between them. There was no evidence from randomized comparative trials to support the contention that patients receiving treatment for PE or DVT with UH are more prone to these complications than those receiving LMWH.
Performance analysis of receive diversity technique for wireless systems using partial channel knowledge

In this paper, we consider Single Input Multiple Output (SIMO) systems with Maximum Ratio Combining(MRC) and Equal Gain Combining (EGC). We assume spatially independent and timely correlated Rayleigh flat fading channels, modeled by AR2 processes. We consider a frame of N+2 symbols, where Channel State Information at Receiver (CSIR) is available in the beginning for two consecutive symbols, also called as partial CSIR. Using this CSIR, we predict CSIR for the remaining N symbols and detect them. For this partially coherent systems, we have derived closed-form expressions of BER for BPSK constellation. We have also presented simulation results and verified our analytical expressions. We have shown the effects of frame size N, time varying condition of channel by doppler frequency ωd on BER. We have compared performance of the SIMO systems with SISO system and shown significant improvement in BER over SISO systems.
Chorion gene amplification in Drosophila: A model for metazoan origins of DNA replication and S-phase control.

The mechanisms controlling duplication of the metazoan genome are only beginning to be understood. It is still unclear what organization of DNA sequences constitutes a chromosomal origin of DNA replication, and the regulation of origin activity during the cell cycle has not been fully revealed. We review recent results that indicate that chorion gene amplification in follicle cells of the Drosophila ovary is a model for investigating metazoan replication. Evaluation of cis sequence organization and function suggests that chorion loci share attributes with other replicons and provides insights into metazoan origin structure. Moreover, recent results indicate that chorion origins respond to S-phase control, but escape mechanisms that inhibit other origins from firing more than once in a cell cycle. Several identified genes that mediate amplification are critical for the cell cycle control of replication initiation. It is likely that further genetic screens for mutations that disrupt amplification will identify the cadre of proteins associated with origins and the regulatory pathways that control their activity. Furthermore, the recent development of methods to detect amplification in situ has uncovered new aspects of its developmental control. Examining this control will reveal links between developmental pathways and the cell cycle machinery. Visualization of amplifying chorion genes with high resolution also represents an opportunity to evaluate the influence of nuclear and chromosome structure on origin activity. The study of chorion amplification in Drosophila, therefore, provides great potential for the genetic and molecular dissection of metazoan replication.
Involvement of Bone Morphogenetic Protein-4 (BMP-4) and Vgr-1 in morphogenesis and neurogenesis in the mouse.

Bone Morphogenetic Protein-4 (BMP-4) and Vgr-1 are members of the TGF-beta gene family most closely related to the Drosophila Decapentaplegic and Xenopus Vg-1 genes. Members of this gene family have been implicated in diverse processes during embryogenesis including epithelial-mesenchymal interactions. Here, we use in situ hybridization to localize BMP-4 and Vgr-1 transcripts during murine development. BMP-4 mRNA is found in a variety of tissues. In the 8.5 days p.c. embryo, transcripts are localized to the mesoderm posterior to the last somite. Later gestation embryos show expression in developing limbs, the embryonic heart, the facial processes and condensed mesenchymal cells associated with early whisker follicle formation. In the developing central nervous system (CNS), BMP-4 expression is restricted to the floor of the diencephalon associated with pituitary development. In contrast, Vgr-1 transcripts are found along the anteroposterior axis of the CNS, in cells immediately adjacent to the floor plate and in the roof plate extending to the forebrain. Together, the data support the hypothesis that polypeptide growth factors of the TGF-beta superfamily play key roles in the initial stages of neurogenesis and organogenesis during murine development.
An Interactive Planetary System for High-Resolution Media Facades

In this demonstration paper we present a first use case of our space-simulation framework targeting media facades and other interactive display environments. This use case displays a planetary system with colliding space objects at the media facade of the Academy of Fine Arts Saar. We further integrated a web-based GUI to allow interaction with the real-time space simulation. Users can connect to the media facade via mobile phones and can directly start to interact with space objects on the facade.