Miracle-dz/UniFAR-FTUs huggingface dataset:
Secure Service Virtualization in IoT by Dynamic Service Dependency Verification

Virtualizing Internet-of-Things (IoT) services is a concept of dynamically building customized high-level IoT services that rely on the real-time data streams flowing from low-level standalone IoT devices. IoT service virtualization is essential when a myriads of IoT devices can get online, interact with each other, exchange data, and based on them create one's own service. Especially, when virtualization occurs across multiple externals domains, it is crucial for clients to verify the source of virtual services, i.e., whether they are built based on authentic original service sources. Also, original services' sources must be constantly aware of the identity of entities who (recursively) virtualize their services. To address these issues, this paper proposes IoT service dependency tree (SDT) validation scheme. SDT uses service dependency trees and dependency signature trees, which enable clients to validate the original sources of a virtual IoT service, verify its service dependency relationships, and have original service sources to be constantly notified of the list of entities (recursively) virtualizing their services. This paper explains SDT scheme and presents use cases for IoT service virtualization where SDT can be applied. Our experimental analysis shows that SDT is scalable for practical use.
Nonlinear Dynamics and Regional Variations in the MJO Skeleton

AbstractA minimal, nonlinear oscillator model is analyzed for the Madden–Julian oscillation (MJO) “skeleton” (i.e., its fundamental features on intraseasonal/planetary scales), which includes the following: (i) a slow eastward phase speed of roughly 5 m s−1, (ii) a peculiar dispersion relation with dω/dk ≈ 0, and (iii) a horizontal quadrupole vortex structure. Originally proposed in recent work by the authors, the fundamental mechanism involves neutrally stable interactions between (i) planetary-scale, lower-tropospheric moisture anomalies and (ii) the envelope of subplanetary-scale, convection/wave activity. Here, the model’s nonlinear dynamics are analyzed in a series of numerical experiments, using either a uniform sea surface temperature (SST) or a warm-pool SST. With a uniform SST, the results show significant variations in the number, strength, and/or locations of MJO events, including, for example, cases of a strong MJO event followed by a weaker MJO event, similar to the Tropical Ocean and Global .
Experimental evidences of redistribution phenomenon in supercapacitors and consequent improvement of their dynamic model

The paper presents a set of experimental investigations related to the study of the dynamic behavior of supercapacitors. The experimentally-inferred results are then used as inputs for an improved version of one of the most common supercapacitor RC-circuit models. The key improvement concerns the accurate modeling of the redistribution phenomenon of the supercapacitor residual charge during charging/discharging and relaxation phases. The accuracy of the obtained model has been experimentally validated. Preliminary physical investigations concerning the temperature effects on the SC dynamic behavior are also presented and discussed.
Retinoid Signaling Determines Germ Cell Fate in Mice

Germ cells in the mouse embryo can develop as oocytes or spermatogonia, depending on molecular cues that have not been identified. We found that retinoic acid, produced by mesonephroi of both sexes, causes germ cells in the ovary to enter meiosis and inititate oogenesis. Meiosis is retarded in the fetal testis by the action of the retinoid-degrading enzyme CYP26B1, ultimately leading to spermatogenesis. In testes of Cyp26b1-knockout mouse embryos, germ cells enter meiosis precociously, as if in a normal ovary. Thus, precise regulation of retinoid levels during fetal gonad development provides the molecular control mechanism that specifies germ cell fate.
Malignant transformation in 1458 patients with potentially malignant oral mucosal disorders: a follow-up study based in a Taiwanese hospital.

BACKGROUND It is generally accepted that the development of cancer in the oral mucosa is preceded by an identifiable non-invasive precursor lesion. The aim of this follow-up study was to estimate the rate and the time to transformation in a group of patients from southern Taiwan with potentially malignant oral epithelial lesions. METHODS The follow-up time is defined as the duration between the onset of the initial diagnosis and the occurrence of confirmed oral cancer. A total of 1458 patients with histological diagnoses of various pre-malignant oral lesions were followed up between 1991 and 2001. The average age at initial diagnosis was 47.5 years. The histological diagnoses were divided into six categories: epithelial dysplasia with hyperkeratosis/epithelial hyperplasia (8.85%); epithelial dysplasia with submucous fibrosis (2.54%); submucous fibrosis (27.57%); hyperkeratosis/epithelial hyperplasia (29.01%); lichen planus (9.80%) and verrucous hyperplasia (22.22%). RESULTS Within the cohort of 1458 patients, 44 patients progressed to oral cancer in the same site as the initial lesions with an overall transformation rate of 3.02% and a mean follow-up time of 42.64 months. Eight of the 166 patients with dysplastic lesions and 15 of 423 patients with hyperkeratosis/epithelial hyperplasia progressed to malignancy. The other patients with malignant transformation originated from various pre-cancerous oral lesions and conditions (submucous fibrosis, eight of 402; lichen planus, three of 143; verrucous hyperplasia, 10 of 324). CONCLUSION These results indicate that patients with pre-malignant oral lesions need long-term follow up.
A Tuned-RF Duty-Cycled Wake-Up Receiver with −90 dBm Sensitivity

A novel wake-up receiver for wireless sensor networks is introduced. It operates with a modified medium access protocol (MAC), allowing low-energy consumption and practical latency. The ultra-low-power wake-up receiver operates with enhanced duty-cycled listening. The analysis of energy models of the duty-cycle-based communication is presented. All the WuRx blocks are studied to obey the duty-cycle operation. For a mean interval time for the data exchange cycle between a transmitter and a receiver over 1.7 s and a 64-bit wake-up packet detection latency of 32 ms, the average power consumption of the wake-up receiver (WuRx) reaches down to 3 μW. It also features scalable addressing of more than 512 bit at a data rate of 128kbit/s−1. At a wake-up packet error rate of 10−2, the detection sensitivity reaches a minimum of −90 dBm. The combination of the MAC protocol and the WuRx eases the adoption of different kinds of wireless sensor networks. In low traffic communication, the WuRx dramatically saves more energy than that of a network that is implementing conventional duty-cycling. In this work, a prototype was realized to evaluate the intended performance.
SERS microscopic imaging as novel tool for assessing viability and enumerating yeast cells at various stages of cell cycle in lag, log, exponential and stationary phases of growth in culture

Surface enhanced Raman scattering (SERS) microscopic imaging was employed to enumerate the yeast cells in culture. We found this imaging method as an efficient tool for easily differentiating and quantitatively enumerating yeast cell at different stages of cell-division cycle (G1, S, G2 and M phase) at various stages of growth phases namely lag, log, exponential and stationary phases in culture. Apart from enumerating the cells at different stages of cell cycle under lag, log, exponential and stationary phases, it was possible using SERS microscopy to differentiate the live cells from dead ones. The dead cells were SERS inactive and gave enhanced autofluorescence compared with the live cells, which were SERS active. The results from the present investigation suggest that SERS microscopic imaging, using silver nanoparticles (AgNPs) as a sensitive tool to enumerate the yeast cells in culture.
Long chain omega-3 fatty acids and cardiovascular disease: a systematic review

Introduction: Cardiovascular disease remains the commonest health problem in developed countries, and residual risk after implementing all current therapies is still high. The use of marine omega-3 fatty acids (DHA and EPA) has been recommended to reduce cardiovascular risk by multiple mechanisms. Objectives: To update the current evidence on the influence of omega-3 on the rate of cardiovascular events. Review Methods: We used the MEDLINE and EMBASE databases to identify clinical trials and randomized controlled trials of omega-3 fatty acids (with quantified quantities) either in capsules or in dietary intake, compared to placebo or usual diet, equal to or longer than 6 months, and written in English. The primary outcome was a cardiovascular event of any kind and secondary outcomes were all-cause mortality, cardiac death and coronary events. We used RevMan 5·1 (Mantel-Haenszel method). Heterogeneity was assessed by the I2 and Chi2 tests. We included 21 of the 452 pre-selected studies. Results: We found an overall decrease of risk of suffering a cardiovascular event of any kind of 10 % (OR 0·90; [0·85–0·96], p = 0·001), a 9 % decrease of risk of cardiac death (OR 0·91; [0·83–0·99]; p = 0·03), a decrease of coronary events (fatal and non-fatal) of 18 % (OR 0·82; [0·75–0·90]; p < 1 × 10− 4), and a trend to lower total mortality (5 % reduction of risk; OR 0·95; [0·89–1·02]; p = 0·15. Most of the studies analyzed included persons with high cardiovascular risk. Conclusions: marine omega-3 fatty acids are effective in preventing cardiovascular events, cardiac death and coronary events, especially in persons with high cardiovascular risk.
Stabilizing Randomly Switched Systems

This article is concerned with stability analysis and stabilization of randomly switched systems under a class of switching signals. The switching signal is modeled as a jump stochastic (not necessarily Markovian) process independent of the system state; it selects, at each instant of time, the active subsystem from a family of systems. Sufficient conditions for stochastic stability (almost sure, in the mean, and in probability) of the switched system are established when the subsystems do not possess control inputs, and not every subsystem is required to be stable. These conditions are employed to design stabilizing feedback controllers when the subsystems are affine in control. The analysis is carried out with the aid of multiple Lyapunov-like functions, and the analysis results, together with universal formulae for feedback stabilization of nonlinear systems, constitute our primary tools for control design.
Time and place: robustness of a traffic analysis attack against web traffic

We consider a timing-only based attack against encrypted and padded web traffic. The attacker can collect training data, but only over a different connection from that against which the attack is directed. This is a significantly easier to perform attack than one which depends on training data collected over the victim link. We demonstrate that an attacker can infer the correct web page >87% of the time when the training data is collected at a distance of up to 25 km from the victim, provided that the type of link is similar e.g. if the victim link uses a cable modem then the training data should be measured over a cable modem link. We also investigate the impact of distance in time between when the training data is collected and when the attack is performed.
Dual-band antenna array with beam steering for mm-waves 5G networks

This work reports an innovative structure and preliminary results of a four-elements antenna array with beam steering for 5G access cellular networks, operating in the underutilized millimetre wave (mm-wave) frequency spectrum. Its structure is based on four slotted-waveguide antenna arrays, which enables to simultaneously perform radiation pattern reconfiguration in the 28 GHz and 38 GHz bands, providing scanning range of 75° and 55° for the lower and higher frequency bands, respectively. The bandwidth varies from 24.19 GHz to 31.42GHz and from 36.61 GHz to 39.22GHz.
Loop-Free Backpressure Routing Using Link-Reversal Algorithms

The backpressure routing policy is known to be a throughput optimal policy that supports any feasible traffic demand in data networks, but may have poor delay performance when packets traverse loops in the network. In this paper, we study loop-free backpressure routing policies that forward packets along directed acyclic graphs (DAGs) to avoid the looping problem. These policies use link reversal algorithms to improve the DAGs in order to support any achievable traffic demand. For a network with a single commodity, we show that a DAG that supports a given traffic demand can be found after a finite number of iterations of the link-reversal process. We use this to develop a joint link-reversal and backpressure routing policy, called the loop free backpressure (LFBP) algorithm. This algorithm forwards packets on the DAG, while the DAG is dynamically updated based on the growth of the queue backlogs. We show by simulations that such a DAG-based policy improves the delay over the classical backpressure routing policy. We also propose a multicommodity version of the LFBP algorithm, and via simulation we show that its delay performance is better than that of backpressure.
Psychiatric genetics in the post-genome age

Less than 50 years after publication of the structure of DNA, we possess a working draft of the human genome and expect a completed draft listing all genes and their location by 2003 ([International Human Genome Sequencing Consortium, 2001][1]). For 21st-century medicine, the genome will offer a
Group B Streptococcus Hijacks the Host Plasminogen System to Promote Brain Endothelial Cell Invasion

Group B Streptococcus (GBS) is the leading cause of meningitis in neonates. We have previously shown that plasminogen, once recruited to the GBS cell surface and converted into plasmin by host-derived activators, leads to an enhancement of bacterial virulence. Here, we investigated whether plasmin(ogen) bound at the GBS surface contributes to blood-brain barrier penetration and invasion of the central nervous system. For that purpose, GBS strain NEM316 preincubated with or without plasminogen plus tissue type plasminogen activator was analyzed for the capacity to adhere to, invade and transmigrate the human brain microvascular endothelial cell (hBMEC) monolayer, and to penetrate the central nervous system using a neonatal mouse model. At earlier times of infection, plasmin(ogen)-treated GBS exhibited a significant increase in adherence to and invasion of hBMECs. Later, injury of hBMECs were observed with plasmin(ogen)-treated GBS that displayed a plasmin-like activity. The same results were obtained when hBMECs were incubated with whole human plasma and infected with untreated GBS. To confirm that the observed effects were due to the recruitment and activation of plasminogen on GBS surface, the bacteria were first incubated with epsilon-aminocaproic acid (εACA), an inhibitor of plasminogen binding, and thereafter with plasmin(ogen). A significant decrease in the hBMECs injury that was correlated with a decrease of the GBS surface proteolytic activity was observed. Furthermore, plasmin(ogen)-treated GBS infected more efficiently the brain of neonatal mice than the untreated bacteria, indicating that plasmin(ogen) bound to GBS surface may facilitate the traversal of the blood-brain barrier. A higher survival rate was observed in offspring born from εACA-treated mothers, compared to untreated mice, and no brain infection was detected in these neonates. Our findings suggest that capture of the host plasmin(ogen) by the GBS surface promotes the crossing of the blood-brain barrier and contributes to the establishment of meningitis.
Evaporation rate of water in hydrophobic confinement

The drying of hydrophobic cavities is believed to play an important role in biophysical phenomena such as the folding of globular proteins, the opening and closing of ligand-gated ion channels, and ligand binding to hydrophobic pockets. We use forward flux sampling, a molecular simulation technique, to compute the rate of capillary evaporation of water confined between two hydrophobic surfaces separated by nanoscopic gaps, as a function of gap, surface size, and temperature. Over the range of conditions investigated (gaps between 9 and 14 Å and surface areas between 1 and 9 nm2), the free energy barrier to evaporation scales linearly with the gap between hydrophobic surfaces, suggesting that line tension makes the predominant contribution to the free energy barrier. The exponential dependence of the evaporation rate on the gap between confining surfaces causes a 10 order-of-magnitude decrease in the rate when the gap increases from 9 to 14 Å. The computed free energy barriers are of the order of 50kT and are predominantly enthalpic. Evaporation rates per unit area are found to be two orders of magnitude faster in confinement by the larger (9 nm2) than by the smaller (1 nm2) surfaces considered here, at otherwise identical conditions. We show that this rate enhancement is a consequence of the dependence of hydrophobic hydration on the size of solvated objects. For sufficiently large surfaces, the critical nucleus for the evaporation process is a gap-spanning vapor tube.
Recent advances in our understanding of Streptococcus pneumoniae infection

A number of significant challenges remain with regard to the diagnosis, treatment, and prevention of infections with Streptococcus pneumoniae (pneumococcus), which remains the most common bacterial cause of community-acquired pneumonia. Although this infection is documented to be extremely common in younger children and in older adults, the burden of pneumonia it causes is considerably underestimated, since the incidence statistics are derived largely from bacteremic infections, because they are easy to document, and yet the greater burden of pneumococcal pneumonias is non-invasive. It has been estimated that for every bacteremic pneumonia that is documented, three non-bacteremic infections occur. Management of these infections is potentially complicated by the increasing resistance of the isolates to the commonly used antibiotics. Furthermore, it is well recognized that despite advances in medical care, the mortality of bacteremic pneumococcal pneumonia has remained largely unchanged over the past 50 years and averages approximately 12%. Much recent research interest in the field of pneumococcal infections has focused on important virulence factors of the organism, on improved diagnostic and prognostication tools, on defining risk factors for death, on optimal treatment strategies involving both antibiotics and adjunctive therapies, and on disease prevention. It is hoped that through these endeavors the outlook of pneumococcal infections will be improved.
Preparation and Application of VE Microcapsules with Polyurethane Shell for Skin-Care Textiles

Vitamin E (VE) microcapsules with polyurethane (PU) shell are successfully prepared via interfacial polymerization of polyurethane with toluene-2,4-diisocyanate (TDI) as the isocyanate, polyethylene glycol as the polyol, and 1,4-butanediol (BD) as the chain extender. In the preparation process, VE emulsion, prepolymer and microencapsulation of VE are studied using a particle size analyzer, butylamine titration, optical microscopy (OM), scanning electron microscopy (SEM), and transmission electron microscopy (TEM). Based on the present research, VE microcapsules prepared have smooth surfaces and spherical appearances, the mean particle size of about 550 nm. Vitamin E microcapsules have been glued effectively to textiles, and a kind of skin-care product has been developed.
Shortest propagation delay (SPD) first scheduling for EPONs with heterogeneous propagation delays

Due to the geographic distribution of its subscribers, Ethernet Passive Optical Networks (EPONs) have typically varying propagation delays between the Optical Network Units (ONUs) and the Optical Line Terminal (OLT). In this paper, we consider EPONs with an offline scheduling framework, which enables Quality-of-Service mechanisms by collecting bandwidth requests from all ONUs before the OLT makes dynamic bandwidth allocations for transmissions on the shared ONUs-to- OLT upstream channel. We propose and evaluate the Shortest Propagation Delay (SPD) first scheduling policy which sequences the ONUs' upstream transmissions in increasing order of the ONUs' propagation delays, i.e., the upstream transmission of the ONU with the smallest propagation delay is scheduled first. We formally analyze the competitiveness of SPD first scheduling and find that it achieves very close to optimal performance. We characterize the stability limit for Gated and Limited grant sizing in conjunction with SPD grant scheduling. We evaluate the cycle length and packet delay with SPD scheduling through probabilistic analysis and simulations and find significant reductions in packet delay with SPD first scheduling in EPONs with heterogeneous propagation delays, especially when Limited grant sizing is employed.
A framework for fiber delay‐line buffers in packet‐based asynchronous multifiber optical networks (PAMFONET)

A major challenge in packet‐based optical networks is packet contention, which occurs when two or more packets are heading to the same output at the same time. To resolve contention in the optical domain, a fundamental approach is fiber delay‐line (FDL) buffering, in which packets can be delayed for a fixed amount of time. In the literature, the performance of FDL buffering has been studied extensively. However, most existing works are based on an assumption that there is only one fiber per link in the network. In this paper, we address the architecture and performance of FDL buffers in packet‐based asynchronous multifiber optical networks (PAMFONET), in which each link in the network may consist of multiple optical fibers. We propose a framework for FDL buffers in PAMFONET, in which we provide three essential architectures and corresponding packet scheduling policies. Extensive simulation results show that, with appropriate settings, the same number of FDLs can lead to better performance in multifiber networks than in single‐fiber networks. Copyright © 2011 John Wiley & Sons, Ltd.
HelpMeter: A Nonlinear Model for Predicting the Helpfulness of Online Reviews

With the flourish of the Internet, online review mining has attracted a lot of attention from the research community. However, compared to various well-studied sentiment analysis and opinion summarization problems, less effort has been made to analyze the quality of online reviews. The objective of this paper is to fill in this gap by automatically evaluating the "helpfulness" of reviews and consequently developing novel models to identify the most helpful reviews for a particular product. In particular, based on a thorough analysis of various factors that may affect the review quality, we propose HelpMeter, a nonlinear regression model for helpfulness prediction. Some preliminary experiments were conducted on a movie review data set, and the performance results confirm the superiority of the proposed method.
The Activity Analysis of Malicious HTTP-Based Botnets Using Degree of Periodic Repeatability

The malicious botnets are evaluated as the serious threat of the Internet society in future. As the botnets are more clever and artful, the detection of botnets is not easy. Recently malicious botnets evolve into HTTP botnets out of typical IRC botnets and it is difficult to response effectively with existing methods which are using DNS traffic. In this paper, we show the relations of HTTP clients to HTTP servers, and propose the method to search malicious HTTP botnets by using degree of periodic repeatability.