Miracle-dz/UniFAR-FTUs huggingface dataset:
Effect of Anemia on Readmission and Death in Octogenarian Patients with Lower Respiratory Tract Infections: A Retrospective Cohort Study

Objectives Lower respiratory tract infection (LRTI) in the octogenarian population is a highly prevalent disorder associated with increased mortality rates. Anemia is a common disorder in older adults and is often left untreated. We investigated whether anemia was a risk factor for LRTI-caused readmission and death in octogenarian patients. Design A retrospective cohort study was designed. Participants. Old patients (age: ≥80 years) hospitalized at the Department of Geriatrics to undergo treatment for LRTIs were included. A total of 215 patients (mean age: 88.73 years; 77.2% men) were studied. The patients were divided into two groups (anemia and non-anemia) based on the hemoglobin level. They were followed up for 1 year after discharge or until mortality event. The primary follow-up outcome was LRTI-caused readmission and/or death. Results The risk of readmission due to LTRI within 1 year of discharge was 2.308 times higher in the anemia group than the risk for the non-anemia group. The number of patients experiencing ≥2 readmissions in the anemia group was significantly higher than that in the non-anemia group (35 (23.5%) vs. 2 (3%), P < 0.001). To prevent readmission of one case, only 2.65 cases with anemia needed to be treated. Furthermore, the risk of LRTI-related deaths was 6.644 times higher in the anemia group than the risk for the non-anemia group. To prevent death of one case, only 3.9 cases with anemia needed to be treated. Statistic results revealed that hemoglobin was an independent protective factor for LRTI-caused readmission (logistic regression method, OR, 0.969; 95% CI, 0.950–0.989) and deaths (Cox regression method, β, −0.037, HR, 0.964; 95% CI, 0.934–0.994). Conclusions Anemia is a widely prevalent and relevant risk factor associated with LRTI-caused readmission and death within 1 year of discharge in octogenarian patients. Trial Registration. This trial is registered with NCT05355324.
Hidden in the highs: Two new species of the enigmatic toadheaded pitvipers of the genus Bothrocophias

Bothrocophias microphthalmus (Cope, 1875) currently comprises most mid- to highland populations of the genus Bothrocophias in the eastern versant of the Andes. We describe two new species of Bothrocophias from the highlands of the Colombian Andes previously referred to as B. microphthalmus based on morphological and genetic evidence. Our phylogenetic analysis revealed that B. micropthalmus as currently recognized is paraphyletic with respect to B. hyoprora, and the two new taxa are sister lineages. These new toadheaded pitvipers can be morphologically distinguished from their congeners based on the presence of contact between the internasal scales, the number of prefoveal scales, the presence of a lacunolabial scale, the arrangement of supralabial scales, ventral scale counts, the color pattern of the dorsal and ventral surfaces of the body and tail, and hemipenial morphology. We discuss some possible taxonomic scenarios for the lineages found within the B. microphthalmus species complex but refrain from making additional taxonomic changes given our reduced sampling of the southern lineages.
A first measurement of the planetary boundary layer top in Cali-Colombia: elastic LiDAR application

The monitoring of the impact of aerosols in Latin America on a local scale is usually limited due to the infrastructure and instrumentation available. In Colombia, there are two international ground surface monitoring networks, the AErosol RObotic NETwork (AERONET) and the Latin American LIDAR NETwork (LALINET). However, the AERONET performance relies on only one sun photometer which makes measurements distributed among five ground-based stations in different cities such as Bogotá and Medellín. On the other hand, LALINET has only one ground-based station formed by an elastic LiDAR system located at Medellín. Although Cali is the largest city of Colombian southwestern, with an accelerated grown rate of both urban and vehicular fleet, and counts with the third largest population of this country, is not reached by these networks. Here, we report on the implementation of a monostatic-coaxial multispectral LiDAR system using a pulsed Nd:YAG laser with 450 mJ of average energy at 1064 nm. To perform the atmospheric measurements, this system is capable of spatially resolving elastic backscatter down to 3.75 m with a Pulse Repetition Frequency (PRF) of 10 Hz. We have developed a hybrid algorithm for data analysis by combining the Fitting and Gradient method and the Klett-Fernald algorithm to estimate the Planetary Boundary Layer (PBL) Top and the optical properties of aerosols. This work constitutes the first quantitative atmospheric exploration to study the aerosols dynamics and the PBL in the northwest of South America.
Antifungal Activity of a Library of Aminothioxanthones

Fungal infections are one of the main causes of mortality and morbidity worldwide and taking into account the increasing incidence of strains resistant to classical antifungal drugs, the development of new agents has become an urgent clinical need. Considering that thioxanthones are bioisosteres of xanthones with known anti-infective actions, their scaffolds were selected for this study. A small library of synthesized aminothioxanthones (1–10) was evaluated for in vitro antifungal activity against Candida albicans, Aspergillus fumigatus, and Trichophyton rubrum; for the active compounds, the spectrum was further extended to other clinically relevant pathogenic fungi. The results showed that only compounds 1, 8, and 9 exhibited inhibitory and broad-spectrum antifungal effects. Given the greater antifungal potential presented, compound 1 was the subject of further investigations to study its anti-virulence activity and in an attempt to elucidate its mechanism of action; compound 1 seems to act predominantly on the cellular membrane of C. albicans ATCC 10231, altering its structural integrity, without binding to ergosterol, while inhibiting two important virulence factors—dimorphic transition and biofilm formation—frequently associated with C. albicans pathogenicity and resistance. In conclusion, the present work proved the usefulness of thioxanthones in antifungal therapy as new models for antifungal agents.
A Bayesian approach to spatial correlations in the multivariate probit model

Ordered categorical data arise in many applied settings. For example, many surveys have responses that may be restricted to “Strongly Disagree”, “Disagree, “Neutral”, “Agree”, and “Strongly Agree”. Here, the responses are ordinal variables. That is, the agreeability of respondents to questions have relative ranks, but there is no measure of exact magnitude like there is with continuous variables. In many scenarios, questions may have correlated responses. As well, different respondents may be spatially or otherwise correlated. Probit models are a means to using normal latent variables in modelling ordinal responses. In this project, we take a Bayesian approach and include both “between question” and “between respondent” correlations in a multivariate probit model. We discuss the efficacy of this spatial multivariate probit model.
Impact of Workplace Status on Employee Expediency and Intention to Sabotage: Mediating Role of Unethical Pro-Supervisor Behavior

Humans have an innate desire to attain high status as it provides the individual with greater resources and benefits. This study particularly focuses on the workplace where status is quite evident. The positive aspect of workplace status dominates in the existing literature by linking it with desirable outcomes, but less attention has been placed on examining its dark side. Utilizing the social influence theory, this study empirically investigates the link between workplace status and employee expediency and intention to sabotage in presence of unethical pro-supervisor behavior as mediator. This study is based on a quantitative research design. Using the Hayes PROCESS technique in SPSS, on three-wave primary data collected (N=250) from employees of service sector organizations in Pakistan, our results reveal that workplace status triggers employee expediency and intention to sabotage through the underlying mechanism of unethical-pro supervisor behavior. This study finds considerable support for all the hypotheses pertaining to direct and indirect effects. Overall, our research extends the literature on the dark side of workplace status and unethical behaviors and advances social influence theory by providing support and offers insightful theoretical and practical implications for inhibiting unethical behaviors in the workplace. Limitations and future research directions have also been discussed at the end.
Adherence to High Dietary Diversity and Incident Cognitive Impairment for the Oldest-Old: A Community-Based, Nationwide Cohort Study

Background and aims: Dietary diversity change is associated with cognitive function, however, whether the effect still exists among the oldest-old (80+) is unclear. Our aim was to examine the effect of dietary diversity changes on cognitive impairment for the oldest-old in a large prospective cohort. Methods: Within the Chinese Longitudinal Healthy Longevity Study, 6237 adults older than 80 years were included. The dietary diversity score (DDS) was assessed by a simplified food frequency questionnaire (FFQ). Cognitive impairment was defined as a Mini-Mental State Examination (MMSE) score lower than 18 points. Cognitive decline was defined as a reduction of total MMSE score ≥3 points, and cognitive decline of different subdomains was defined as a reduction of ≥15% in the corresponding cognitive domain. The multivariate-adjusted Cox proportional hazard model evaluated the effects of DDS change on cognitive decline. The linear mixed-effect model was used to test subsequent changes in MMSE over the years. Results: During 32,813 person-years of follow-up, 1829 participants developed cognitive impairment. Relative to the high–high DDS change pattern, participants in the low–low and high–low patterns were associated with an increased risk of cognitive impairment with a hazard ratio (95% confidential interval, CI) of 1.43 (1.25, 1.63) and 1.44 (1.24, 1.67), and a faster decline in the MMSE score over the follow-up year. Participants with the low–high pattern had a similar incidence of cognitive impairment with HRs (95% CI) of 1.03 (0.88, 1.20). Compared with the stable DDS status group (−1–1), the risk of cognitive impairment was higher for those with large declines in DDS (≤−5) and the HR was 1.70 (95% CI: 1.44, 2.01). Conclusions: Even for people older than 80, dietary diversity change is a simple method to identify those who had a high risk of cognitive decline. Keeping high dietary diversity is beneficial for cognitive function and its subdomain even in the final phase of life, especially for females and the illiterate oldest-old.
A Paradox over Electric Vehicles, Mining of Lithium for Car Batteries

Lithium, a silver-white alkali metal, with significantly high energy density, has been exploited for making rechargeable lithium-ion batteries (LiBs). They have become one of the main energy storage solutions in modern electric cars (EVs). Cobalt, nickel, and manganese are three other key components of LiBs that power electric vehicles (EVs). Neodymium and dysprosium, two rare earth metals, are used in the permanent magnet-based motors of EVs. The operation of EVs also requires a high amount of electricity for recharging their LiBs. Thus, the CO2 emission is reduced during the operation of an EV if the recharged electricity is generated from non-carbon sources such as hydroelectricity, solar energy, and nuclear energy. LiBs in EVs have been pushed to the limit because of their limited storage capacity and charge/discharge cycles. Batteries account for a substantial portion of the size and weight of an EV and occupy the entire chassis. Thus, future LiBs must be smaller and more powerful with extended driving ranges and short charging times. The extended range and longevity of LiBs are feasible with advances in solid-state electrolytes and robust electrode materials. Attention must also be focused on the high-cost, energy, and time-demand steps of LiB manufacturing to reduce cost and turnover time. Solid strategies are required to promote the deployment of spent LiBs for power storage, solar energy, power grids, and other stationary usages. Recycling spent LiBs will alleviate the demand for virgin lithium and 2.6 × 1011 tons of lithium in seawater is a definite asset. Nonetheless, it remains unknown whether advances in battery production technology and recycling will substantially reduce the demand for lithium and other metals beyond 2050. Technical challenges in LiB manufacturing and lithium recycling must be overcome to sustain the deployment of EVs for reducing CO2 emissions. However, potential environmental problems associated with the production and operation of EVs deserve further studies while promoting their global deployment. Moreover, the combined repurposing and remanufacturing of spent LiBs also increases the environmental benefits of EVs. EVs will be equipped with more powerful computers and reliable software to monitor and optimize the operation of LiBs.
Towards Automated Classification of Zooplankton Using Combination of Laser Spectral Techniques and Advanced Chemometrics

Zooplankton identification has been the subject of many studies. They are mainly based on the analysis of photographs (computer vision). However, spectroscopic techniques can be a good alternative due to the valuable additional information that they provide. We tested the performance of several chemometric techniques (principal component analysis (PCA), non-negative matrix factorisation (NMF), and common dimensions and specific weights analysis (CCSWA of ComDim)) for the unsupervised classification of zooplankton species based on their spectra. The spectra were obtained using laser-induced breakdown spectroscopy (LIBS) and Raman spectroscopy. It was convenient to assess the discriminative power in terms of silhouette metrics (Sil). The LIBS data were substantially more useful for the task than the Raman spectra, although the best results were achieved for the combined LIBS + Raman dataset (best Sil = 0.67). Although NMF (Sil = 0.63) and ComDim (Sil = 0.39) gave interesting information in the loadings, PCA was generally enough for the discrimination based on the score graphs. The distinguishing between Calanoida and Euphausiacea crustaceans and Limacina helicina sea snails has proved possible, probably because of their different mineral compositions. Conversely, arrow worms (Parasagitta elegans) usually fell into the same class with Calanoida despite the differences in their Raman spectra.
Magnetic order-disorder transition in the two-dimensional spatially anisotropic Heisenberg model at zero temperature

The ground-state properties of the spin-1/2 antiferromagnetic Heisenberg model with spatially anisotropic couplings on a square lattice are investigated by a spin-rotation-invariant Green's-function approach and by Lanczos diagonalizations on lattices up to 36 sites supplemented by finite-size scaling. We focus on the anisotropy-driven transition from the N\'eel state to a paramagnetic state with antiferromagnetic short-range order and on the spatial dependence of spin correlation functions. Our principal result is that a rather sharp crossover in the magnetic behavior occurs at the coupling ratio ${R}_{0}\ensuremath{\simeq}0.2 {(R=J}_{y}{/J}_{x}). $
Logarithmic potential for the gravitational field of Schwarzschild black holes

Approximate gravitational potentials are often used to describe analytically the motion of particles near black holes (BHs), as well as to study the structure of an accretion disk. Such 'pseudo-Newtonian' potentials are used with the flat-metric equations. Here we consider the motion of a free particle near a non-rotating BH in the context of an exact `logarithmic' gravitational potential. We show how the logarithmic potential gives an exact solution for a mechanical problem and present the relativistic Bernoulli equation for the fluid in the Schwarzschild metric.
Dual pathways of intergenerational influence over multiple generations

Abstract The traditional approach to studying intergenerational influences has been limited to a single-stranded framework, with a focus on the transmission of socioeconomic status across two generations. In this paper, we develop a theoretical model of dual-pathway intergenerational influence over multiple generations and test the model by utilizing recent high-quality three-generation panel data from China. The model consists of two intertwined pathways: a socioeconomic pathway measured with educational attainment and a psychological pathway measured with mindset. We show that mindset is a fundamental psychological factor strongly associated with multiple outcomes, including cognitive skills, personalities, and attitudes. Intergenerational influences operate via the transmissions of both mindset and socioeconomic status as well as the cross-domain pathways between the two. Our results offer new insights for a better understanding of intergenerational mobility and immobility.
HUBBLE SPACE TELESCOPE DISCOVERY OF A z = 3.9 MULTIPLY IMAGED GALAXY BEHIND THE COMPLEX CLUSTER LENS WARPS J1415.1+36 AT z = 1.026

We report the discovery of a multiply lensed Lyα emitter at z = 3.90 behind the massive cluster WARPS J1415.1+3612 at z = 1.026. Images taken by the Hubble Space Telescope using the Advanced Camera for Surveys reveal a complex lensing system that produces a prominent, highly magnified arc and a triplet of smaller arcs grouped tightly around a spectroscopically confirmed cluster member. Spectroscopic observations using the Faint Object Camera and Spectrograph on Subaru confirm strong Lyα emission in the source galaxy and provide the redshifts for more than 21 cluster members with a velocity dispersion of 807 ± 185 km s−1. Assuming a singular isothermal sphere profile, the mass within the Einstein ring (7.13 ± 0.″38) corresponds to a central velocity dispersion of 686+15−19 km s−1 for the cluster, consistent with the value estimated from cluster member redshifts. Our mass profile estimate from combining strong lensing and dynamical analyses is in good agreement with both X-ray and weak lensing results.
Quadratus Lumborum Block in Caesarean Section: A Case Report

Introduction: Quadratus lumborum (QLB) block is a posterior abdominal wall block (interfascial plane block) with ultrasound guidance. This study describes the administration of quadratus lumborum block as pain management on C-section. Case presentation: A woman, 31 years old, G2P1A0 post-C-section 4 years ago, is planning to undergo elective C-Section surgery. Vital sign examination within normal limits. The patient was included in the ASA II category. Prior to surgery, the patient was given premedication in the form of omeprazole 40 mg intravenously, paracetamol 1 gram intravenous drip for 15 minutes, and metoclopramide 10 mg intravenously. Quadratus lumborum block was given postoperatively. Postoperative management consisted of ibuprofen 800 mg/8 hour drip for 30 minutes and paracetamol 750 mg/6 hour drip. Conclusion: Pain management with the QLB method reduces postoperative acute pain and recovery. Further studies with a wider population are needed to explore the efficacy and effectiveness of QLB blocks.
Screening bile salt hydrolase activity of Lactobacillus isolated from Vietnamese human origins

Hypercholesterolemia is a major cause of cholesterol build-up in the coronary arteries, which can subsequently lead to heart disease or atherosclerosis. Cholesterol levels can be lowered by cholesterol-lowering drugs but some of these drugs may have harmful side effects, while supplementation of Lactobacillus has shown the potential to reduce serum cholesterol levels by virtue of bile salt hydrolase (bsh) activity. In this study, Lactobacillus plantarum VFE-04, L. rhamnosus VFE-08, and L. plantarum VFE-14, had been isolated from Vietnamese healthy adults, were able to deconjugate glycodeoxycholate (GDC) on MRS plates and MRS broth supplemented with GDC. In addition, deconjugating activity of L. plantarum VFE-04, L. rhamnosus VFE-08, and L. plantarum VFE-14 were also found in cell-free extract as expressed by amount of glycine that released in the supernatant. Four bsh genes including bsh1, bsh2, bsh3, and bsh4 have been identified by PCR in these strains. In addition, L. plantarum VFE-04, L. rhamnosus VFE-08, and L. plantarum VFE-14 also showed high ability to resist bile salts and low pH. The results of 16S rRNA gene analyses showed that L. plantarum VFE-04, L. rhamnosus VFE-08, and L. plantarum VFE-14 and had high similarity scores with L. plantarum ZZU 23 (100%), L. rhamnosus JCM 1136 (99%) and L. plantarum S7 (98.65%), respectively. This study suggests that L. plantarum VFE-04, L. rhamnosus VFE-08, and L. plantarum VFE-14 have the potential to be explored as probiotics in the management of hypercholesterolaemia in near future.
Massive Stars in the Arches Cluster

We present and use new spectra and narrowband images, along with previously published broadband images, of stars in the Arches cluster to extract photometry, astrometry, equivalent width, and velocity information. The data are interpreted with a wind/atmosphere code to determine stellar temperatures, luminosities, mass-loss rates, and abundances. We have doubled the number of known emission-line stars, and we have also made the first spectroscopic identification of the main sequence for any population in the Galactic center. We conclude that the most massive stars are bona fide Wolf-Rayet (W-R) stars; are some of the most massive stars known, having Minit > 100 M☉; and have prodigious winds, Ṁ > 10-5 M☉ yr-1, that are enriched with helium and nitrogen; with these identifications, the Arches cluster contains about 5% of all known W-R stars in the Galaxy. We find an upper limit to the velocity dispersion of 22 km s-1, implying an upper limit to the cluster mass of 7 × 104 M☉ within a radius of 0.23 pc; we also estimate the bulk heliocentric velocity of the cluster to be vcluster, ☉ ≈ +95 km s-1. Taken together, these results suggest that the Arches cluster was formed in a short, but massive, burst of star formation about 2.5 ± 0.5 Myr ago, from a molecular cloud that is no longer present. The cluster happens to be approaching and ionizing the surface of a background molecular cloud, thus producing the thermal arched filaments. We estimate that the cluster produces 4 × 1051 ionizing photons s-1, more than enough to account for the observed thermal radio flux from the nearby cloud, 3 × 1049 ionizing photons s-1. Commensurately, it produces 107.8 L☉ in total luminosity, providing the heating source for the nearby molecular cloud, Lcloud ≈ 107 L☉. These interactions between a cluster of hot stars and a wayward molecular cloud are similar to those seen in the "Quintuplet/Sickle" region. The small spread of formation times for the known young clusters in the Galactic center and the relative lack of intermediate-age stars (τage = 107.0-107.3 yr) suggest that the Galactic center has recently been host to a burst of star formation. Finally, we have made new identifications of near-infrared sources that are counterparts to recently identified X-ray and radio sources.
Practical free-space quantum key distribution over 1 km

A working free-space quantum key distribution system has been developed and tested over an outdoor optical path of {approximately}1 km at Los Alamos National Laboratory under nighttime conditions. Results show that free-space quantum key distribution can provide secure real-time key distribution between parties who have a need to communicate secretly. Finally, we examine the feasibility of surface to satellite quantum key distribution. {copyright} {ital 1998} {ital The American Physical Society}