Miracle-dz/UniFAR-FTUs huggingface dataset:
L dwarfs in the Hyades

We present the results of a proper motion survey of the Hyades to search for brown dwarfs, based on UKIRT Deep Sky Survey (UKIDSS) and Two-Micron All Sky Survey (2MASS) data. This survey covers ∼275 deg 2 to a depth of K ∼ 15 mag, equivalent to a mass of ∼0.05 M ⊙ assuming a cluster age of 625 Myr. The discovery of 12 L dwarf Hyades members is reported. These members are also brown dwarfs, with masses between 0.05 < M < 0.075 M ⊙ . A high proportion of these L dwarfs appear to be photometric binaries.
On a robust document classification approach using TF-IDF scheme with learned, context-sensitive semantics.

Document classification is a well-known task in inf ormation retrieval domain and relies upon various indexing schemes to map documents into a form that can be consumed by a classification system. Term Frequency-Inverse Document Frequency (TF-IDF) is one such class of term-weighing functions used extensively for document representat ion. One of the major drawbacks of this scheme is that i t ignores key semantic links between words and/or word meanings and compares documents based solely on the word frequencies. Majority of the current approaches tha t try to address this issue either rely on alternate repres entation schemes, or are based upon probabilistic models. We utilize a non-probabilistic approach to build a robust docu ment classification system, which essentially relies up on enriching the classical TF-IDF scheme with contextsensitive semantics using a neural-net based learni ng component.
A Subtle Interplay Between Three Pex11 Proteins Shapes De Novo Formation and Fission of Peroxisomes

The organization of eukaryotic cells into membrane‐bound compartments must be faithfully sustained for survival of the cell. A subtle equilibrium exists between the degradation and the proliferation of organelles. Commonly, proliferation is initiated by a membrane remodeling process. Here, we dissect the function of proteins driving organelle proliferation in the particular case of peroxisomes. These organelles are formed either through a growth and division process from existing peroxisomes or de novo from the endoplasmic reticulum (ER). Among the proteins involved in the biogenesis of peroxisomes, peroxins, members of the Pex11 protein family participate in peroxisomal membrane alterations. In the yeast Saccharomyces cerevisiae, the Pex11 family consists of three proteins, Pex11p, Pex25p and Pex27p. Here we demonstrate that yeast mutants lacking peroxisomes require the presence of Pex25p to regenerate this organelle de novo. We also provide evidence showing that Pex27p inhibits peroxisomal function and illustrate that Pex25p initiates elongation of the peroxisomal membrane. Our data establish that although structurally conserved each of the three Pex11 protein family members plays a distinct role. While ScPex11p promotes the proliferation of peroxisomes already present in the cell, ScPex25p initiates remodeling at the peroxisomal membrane and ScPex27p acts to counter this activity. In addition, we reveal that ScPex25p acts in concert with Pex3p in the initiation of de novo peroxisome biogenesis from the ER.
MCS - Multimodality Classification System: classificando objetos de aprendizagem quanto à multimodalidade

The contribution of this article is the proposition of a systematic classification of learning objects regarding their multimodality. This systematic considers the existence of several multimodality categories, some of them ineffective to apprenticeship and some that aim to an affective support of building knowledge. After creating categories, it was built an app called MCS Multimodality Classification System, which has been tested. In the end of the process, it is expected, with this pattern applied, to help teachers seeking and choosing material to teach their students.
Radial basis function Network based on multi-objective particle swarm optimization

The problem of unsupervised and supervised learning is discussed within the context of multi-objective optimization. In this paper, an evolutionary multi-objective selection method of RBF Networks structure is discussed. The candidates of RBF Network structure are encoded into the particles in PSO. Then, they evolve toward Pareto-optimal front defined by several objective functions concerning with model accuracy and model complexity. This study suggests an approach of RBF Network training through simultaneous optimization of architectures and weights with PSO-based multi-objective algorithm. Our goal is to determine whether Multi-objective PSO can train RBF Networks, and the performance is validated on accuracy and complexity. The experiments are conducted on benchmark datasets obtained from the UCI machine learning repository. The results show that our proposed method provides an effective means for training RBF Networks that is competitive with other evolutionary computational-based methods.
Early Experience on Transactional Execution of Java TM Programs Using Intel R © Transactional Synchronization Extensions

This paper applies Intel R © Transactional Synchronization Extensions (Intel R © TSX) to elide Java monitor locks. By utilizing the transactional execution capability inside a Java Virtual Machine (JVM), applications running on top of the JVM transparently benefit without source or bytecode modifications. While others have previously examined transactional execution of Java programs, we find that the absence of a guarantee on eventual transactional commit requires a software fallback, and present a novel design where the fallback code harmoniously coexists with the JVM locking mechanism. We also find that if not used judiciously, a real implementation of hardware transactional memory can significantly degrade application performance. Therefore, we propose an adaptive algorithm that selectively deoptimizes transactional lock elision where necessary. Evaluation of the Intel TSX-enabled JVM with various Java workloads shows promising results. For workloads that utilize a significant number of coarse-grained monitors, transactional lock elision provides a substantial performance improvement: up to 1.18x on a standard Java benchmark suite. In contrast, on workloads with monitor locks that are hard to elide, our adaptive deoptimization approach prevents significant performance degradation from lock elision overheads.
Adolescents' Neural Processing of Risky Decisions: Effects of Sex and Behavioral Disinhibition

Background Accidental injury and homicide, relatively common among adolescents, often follow risky behaviors; those are done more by boys and by adolescents with greater behavioral disinhibition (BD). Hypothesis Neural processing during adolescents' risky decision-making will differ in youths with greater BD severity, and in males vs. females, both before cautious behaviors and before risky behaviors. Methodology/Principal Findings 81 adolescents (Patients with substance and conduct problems, and comparison youths (Comparisons)), assessed in a 2 x 2 design (Patients:Comparisons x Male:Female) repeatedly decided between doing a cautious behavior that earned 1 cent, or a risky one that either won 5 or lost 10 cents. Odds of winning after risky responses gradually decreased. Functional magnetic resonance imaging captured brain activity during 4-sec deliberation periods preceding responses. Most neural activation appeared in known decision-making structures. Patients, who had more severe BD scores and clinical problems than Comparisons, also had extensive neural hypoactivity. Comparisons' greater activation before cautious responses included frontal pole, medial prefrontal cortex, striatum, and other regions; and before risky responses, insula, temporal, and parietal regions. Males made more risky and fewer cautious responses than females, but before cautious responses males activated numerous regions more than females. Before risky behaviors female-greater activation was more posterior, and male-greater more anterior. Conclusions/Significance Neural processing differences during risky-cautious decision-making may underlie group differences in adolescents' substance-related and antisocial risk-taking. Patients reported harmful real-life decisions and showed extensive neural hypoactivity during risky-or-cautious decision-making. Males made more risky responses than females; apparently biased toward risky decisions, males (compared with females) utilized many more neural resources to make and maintain cautious decisions, indicating an important risk-related brain sexual dimorphism. The results suggest new possibilities for prevention and management of excessive, dangerous adolescent risk-taking.
Diagnosis Accuracy of Mean Arterial Pressure Variation during a Lung Recruitment Maneuver to Predict Fluid Responsiveness in Thoracic Surgery with One-Lung Ventilation

Background. Lung recruitment maneuver (LRM) during thoracic surgery can reduce systemic venous return and resulting drop in systemic blood pressure depends on the patient's fluid status. We hypothesized that changes in systemic blood pressure during the transition in LRM from one-lung ventilation (OLV) to two-lung ventilation (TLV) may provide an index to predict fluid responsiveness. Methods. Hemodynamic parameters were measured before LRM (T0); after LRM at the time of the lowest mean arterial blood pressure (MAP) (T1) and at 3 minutes (T2); before fluid administration (T3); and 5 minutes after ending it (T4). If the stroke volume index increased by >25% following 10 mL/kg colloid administration for 30 minutes, then the patients were assigned to responder group. Results. Changes in MAP, central venous pressure (CVP), and stroke volume variation (SVV) between T0 and T1 were significantly larger in responders. Areas under the curve for change in MAP, CVP, and SVV were 0.852, 0.759, and 0.820, respectively; the optimal threshold values for distinguishment of responders were 9.5 mmHg, 0.5 mmHg, and 3.5%, respectively. Conclusions. The change in the MAP associated with LRM at the OLV to TLV conversion appears to be a useful indicator of fluid responsiveness after thoracic surgery. Trial Registration. This trial is registered at Clinical Research Information Service with KCT0000774.
Etectin Ties Usin Ate Xamples

Verifying the fidelity of domain representation in large knowledge bases (KBs) is a difficult problem: domain experts are typically not experts in knowledge representation languages, and as knowledge bases grow more complex, visual inspection of the various terms and their abstract definitions, their interrelationships and the limiting, boundary cases becomes much harder. This paper presents an approach to help verify and refine abstract term definitions in knowledge bases. It assumes that it is easier for a domain expert to determine the correctness of individual concrete examples than it is to verify and correct all the ramifications of an abstract, intensional specification. To this end, our approach presents the user with an interface in which abstract terms in the KB are described using examples and natural language generated from the underlying domain representation. Problems in the KB are therefore manifested as problems in the generated description. The user can then highlight specific examples or parts of the explanation that seem problematic. The system reasons about the underlying domain model by using the discourse plan generated for the description. This paper briefly describes the working of the system and illustrates three possible types of problem manifestations using an example of a specification of fl oating-point numbers in Lisp.
Cebuano Music Videos for Mother Tongue Based Multi-Lingual Education: An Instructional Material For Kindergarten, Grades I, II, and III

The Philippine educational system is becoming gradually competitive for the institutions and its students. The Department of Education’s new trend K-12 implementation of Mother-Tongue-based Multilingual Education (MTB-MLE) wherein the kindergarten and grades one to three are required to have a subject that SMCC Computing Journal ISSN Print: 2508-0539 · ISSN Online: 2508-0547 Volume 1 · June 2018 SMCC Computing Journal 20 uses the child’s mother tongue as the language, is one good example that best describes today’s improving educational system. Students must acquire learnings as much as they can, and acquire it effectively. With this new implementation, the proponents searched for problems that might serve as a hindrance in successfully putting into effect the said implementation. And out of the many problems that make it impossible for the implementation to be actualized listed in Section 5 of the Republic Act No. 10157, the proponents focused on the problem that when resources, in utilizing the mother tongue, are not yet accessible. The purpose of this paper is to eliminate the listed problem and to utilize information technology in formulating a solution to the said problem. The proponents came up with the idea of an interactive learning tool, so the proponents searched for available Cebuano music videos that consist of nursery rhymes that serve as a learning tool for the mother tongue. A limited number of Cebuano music videos were found, that led the proponents to proceed in making music videos using Cebuano language. The music videos will compose of animations and old and new Cebuano nursery rhymes. After successfully making the music videos they become more competitive that leads them to intensify their standards. The proponents believe that these Cebuano music videos will become a very popular choice for an effective tool in learning Cebuano mother tongue.
Integrating Personalized Health Information from MedlinePlus in a Patient Portal

The objective of this paper is to describe the implementation and use of context aware information in Spanish from MedlinePlus embedded in a Patient Portal. Personalized information can help patients solve problems, make treatment decisions, gain confidence in their ability to care for themselves and communicate with providers. To integrate MedlinePlus information in our institutional PHR we used the HL7 Context-Aware Knowledge Retrieval Standard, also known as the Infobutton Standard. After analysing one year of use, patients accessed MedlinePlus information in Spanish in a similar rate to other personalized information generated locally. Infobuttons associated to laboratory test results were used in approximately 10% of patients portal sessions when reviewing lab results.
Shaping dialogues with a humanoid robot based on an E-learning system

This paper examines a type of dialogue between an instructor and a humanoid robot, which is particularly appropriate for a situation wherein students listen to an instructor-robot dialogue in a classroom. The type of dialogue is extracted from comedy routines, movie plots, and a science experiment-based television program. The general structure of the dialogue is a series of activation, core, and feedback events. To interact with students and to obtain information from a web-based learning system, the activation and feedback are assigned to the instructor, whereas the robot participates in the core. In the activation phase, the instructor provides a topic keyword to enable the robot to submit a universal resource locator query request. The Topic Maps ontology of the web system enables the robot to speak regarding the topic in the core phase. Finally, the instructor clarifies the point in the feedback phase to motivate the interest and fun of the topic.
Privacy Preserving Multi-factor Authentication Schemes in a Distributed environment : An Overview

Remote user authentication has become an important technique in a distributed environment in which the services are distributed and devices are untrusted. A remote user authentication method is used to validate the legitimate remote client. And it is one of the vital security services. Many more authentication mechanisms were proposed to determine the identity of a remote client. This paper provides an overview of several multifactor authentication mechanisms which preserves privacy and security in a distributed environment.
A measure to assess the behavior of method stereotypes in object-oriented software

The implementation of software systems should ideally follow the design intentions of the system. However, this is not always the case - the design and implementation of software systems may diverge during software evolution. In this paper we propose a measure based on run time information to assess the consistency between the design and the implementation of OO methods. The measure is based on the analysis of the runtime behavior of methods and considers the frequency of fan-in and fan-out method calls. We analyze this measure with respect to the design intent of methods, reflected by their stereotype. We apply the proposed approach to data from three open source software systems and analyze the behavior of method stereotypes across the systems and within each system. The analysis shows that most methods behave as expected based on their stereotypes and it also detects cases that may need re-engineering attention.
Octopamine Mediates Thermal Preconditioning of the Locust Ventilatory Central Pattern Generator via a cAMP/Protein Kinase A Signaling Pathway

We investigated the role of biogenic amines in generating thermoprotection of the ventilatory motor pattern circuitry in Locusta migratoria. Levels of octopamine (OA) and dopamine (DA) in the metathoracic ganglion decreased during heat stress. We measured the thermosensitivity of central pattern generation in response to a ramped increase of temperature in semi-intact preparations. OA, DA, and tyramine (TA) were either bath applied or injected into the locust hemocoel 4–8 h before testing. Neither TA nor DA modified the thermotolerance of ventilatory motor pattern generation. However, OA treatment by bath applications (10−4 m OA) or by injections into the hemocoel (2 μg/10 μl OA) mimicked heat shock preconditioning and improved the thermotolerance of the motor pattern by increasing the failure temperature and by decreasing the time taken to recover operation after a return to room temperature. Heat shock-induced thermoprotection was eradicated in locusts preinjected with epinastine (OctβR antagonist). Neuropil injections of the cAMP agonist and protein kinase A (PKA) activator, Sp-cAMPs, both conferred thermoprotection in control locusts and rescued thermoprotection in epinastine-treated HS locusts. Similar injections of the PKA inhibitor Rp-cAMPs blocked the thermoprotective effect of bath-applied OA. Octopamine-mediated thermoprotection was also abolished with neuropil injections of cycloheximide or actinomycin D, indicating a requirement for transcription and translation. We conclude that OA has a crucial role in triggering protein synthesis-dependent physiological adaptations to protect CNS function during heat stress by activating a cAMP/PKA pathway.
Computing the Optimal Game

In many multiagent environments, a designer has some, but limited control over the game being played. In this paper, we formalize this by considering incompletely specified games, in which some entries of the payoff matrices can be chosen from a specified set. We show that it is NP-hard for the designer to decide whether she can make her choices so that no action in a given set gets played in equilibrium. Hardness holds even in zero-sum games and even in weak tournament games (which are symmetric zero-sum games whose entries are all −1, 0, or 1). The latter case is closely related to the necessary winner problem for a social-choice-theoretic solution concept. We then give a mixed-integer linear programming formulation for weak tournament games and evaluate it experimentally.
On the scaling of waiting-time distributions of the negative IMF B z component

Statistics associated with the fluctuations in solar wind parameters show a remarkable dependence on the solar activity phase. In particular, we focus our attention on the waiting-time statistics governing the MHD fluctuations of the z-component of the interplanetary magnetic field, which are important within the framework of the Sun-Earth connections, and briefly discuss the preliminary results. Data from several spacecrafts, covering different phases of the solar cycle and different radial distances, are used. We found that propagating Alfvenic fluctuations and convected structures strongly influence the statistics which vary from quasi-Poissonian to power law.
The mitochondrial genomes of the iguana ( Iguana iguana ) and the caiman ( Caiman crocodylus ) : implications for amniote phylogeny

The mitochondrial genomes of the iguana (Iguana iguana) and the caiman (Caiman crocodylus): implications for amniote phylogeny The mitochondrial genomes of the iguana (Iguana iguana) and the caiman (Caiman crocodylus): implications for amniote phylogeny. Royal Society of London. General rights Copyright and moral rights for the publications made accessible in the public portal are retained by the authors and/or other copyright owners and it is a condition of accessing publications that users recognise and abide by the legal requirements associated with these rights. • Users may download and print one copy of any publication from the public portal for the purpose of private study or research. • You may not further distribute the material or use it for any profit-making activity or commercial gain • You may freely distribute the URL identifying the publication in the public portal ? Take down policy If you believe that this document breaches copyright please contact us providing details, and we will remove access to the work immediately and investigate your claim. The mitochondrial genomes of the iguana (Iguana iguana) and the caiman (Caiman crocodylus): implications for amniote phylogeny The complete mitochondrial genomes of two reptiles, the common iguana (Iguana iguana) and the caiman (Caiman crocodylus), were sequenced in order to investigate phylogenetic questions of tetrapod evolution. The addition of the two species allows analysis of reptilian relationships using data sets other than those including only fast-evolving species. The crocodilian mitochondrial genomes seem to have evolved generally at a higher rate than those of other vertebrates. Phylogenetic analyses of 2889 amino-acid sites from 35 mitochondrial genomes supported the bird^crocodile relationship, lending no support to the Haematotherma hypothesis (with birds and mammals representing sister groups). The analyses corroborated the view that turtles are at the base of the bird^crocodile branch. This position of the turtles makes Diapsida paraphyletic. The origin of the squamates was estimated at 294 million years (Myr) ago and that of the turtles at 278 Myr ago. Phylogenetic analysis of mammalian relationships using the additional outgroups corroborated the Marsupionta hypothesis, which joins the monotremes and the marsupials to the exclusion of the eutherians.
Is there a clubbing effect underlying Chinese research citation Increases?

There is increasing evidence that citations to Chinese research publications are rising sharply. A series of reasons have been highlighted in previous studies. This research explores another possibility—whether there is a “clubbing” effect in China's surge in research citations, in which a higher rate of internal citing takes place among influential Chinese researchers. Focusing on the most highly cited research articles in nanotechnology, we find that a larger proportion of Chinese nanotechnology research citations are localized within individual, institutional, and national networks within China. Both descriptive and statistical tests suggest that highly cited Chinese papers are more likely than similar U.S. papers to receive internal and localized citations. Tentative explanations and policy implications are discussed.