Miracle-dz/UniFAR-FTUs huggingface dataset:
RADIOCARBON DATING OF THE MAJOR SETTLEMENT AT SKARKOS (IOS ISLAND, CYCLADES) AND INFERENCES FOR THE EARLY CYCLADIC CHRONOLOGY

ABSTRACT We have radiocarbon-dated the main settlement of Skarkos (Skarkos II) on the Cycladic island of Ios, using a set of animal bone samples. The site of Skarkos stands on a hill in a coastal plain, mid-way down the western side of Ios island and about 1 km from the island’s harbour. It is the first time this important settlement with a wealth of finds and an extraordinary building system with two-storey houses is dated in absolute terms complementing the chronology of the Cycladic EBA II period. The radiocarbon determinations show that the major phase of the settlement came to an end between circa 2550 and circa 2500 BC. The dates also confirm the archaeological evidence that the main occupation period is dated archaeologically to the EC II period (Keros-Syros culture). Furthermore, in order to embed the new Skarkos dates within the overall Cycladic chronology and define better the end of the EC II phase, we treated the Skarkos dates together with published dates from other Cycladic sites using Bayesian analysis considering two different models.
Solutions-Based Approach to Urban Cat Management—Case Studies of a One Welfare Approach to Urban Cat Management

Simple Summary When multiple urban free-roaming cats are being cared for by an owner or a cat caregiver, it often results in public complaints due to concerns about nuisance behaviors, their effect on wildlife, and human and pet health. The typical response from the authorities is to implement a cat management strategy based on trap–adopt or kill. Because the cats are often timid or shy, many are euthanized. This strategy is detrimental to the well-being of the people who care for urban cats, and is not effective at reducing the free-roaming cat population. This qualitative study aimed to explore the impacts of a free sterilization, microchipping, and vaccination program on the people who care for multiple urban free-roaming cats. Several main themes arose during the interviews. The results demonstrate the strong bond the participants had with the cats they cared for, and the positive impact the free sterilization program had on the cat carers’ well-being and quality of life. It is recommended that this care-centered approach be used instead of current lethal cat management strategies, to improve the well-being of people and cats, reduce the free-roaming cat population, and minimize public complaints and cat impoundments. Abstract Urban free-roaming cats create concern about their impacts on wildlife and human health, leading to the use of trap–adopt–kill methods to manage these populations. This method is ineffective at decreasing the free-roaming cat population and has a negative impact on cat caregivers’ well-being. Using semi-structured interviews, this study explored the relationship that semi-owners (people who feed cats but do not perceive ownership) and owners of multiple cats have with the cats they care for, and the social and psychological impacts of an alternative assistive-centered approach to urban cat management. This approach to semi-owned and owned cats provided free sterilization and preventative healthcare. Our findings demonstrate that the caregivers had a strong emotional bond with the cats they cared for. The caregivers also experienced a positive impact on their quality of life, and indicated an improvement in the cats’ welfare after having the cats sterilized through this program. Additionally, the cat caregivers indicated that they had a negative view of agencies, such as the municipal council. It is recommended that an assistive-centered approach to urban cat management be prioritized by local councils and welfare agencies to improve caregivers’ quality of life and psychological well-being, whilst also improving cat welfare. The implementation of this assistive-centered management approach could improve the relationship between communities and the agencies involved, leading to the continuous reporting of free-roaming cats for sterilization. This assistive-centered approach has the potential to reduce the free-roaming cat population, their effects on wildlife, nuisance complaints, and council impoundments, and is aligned with the One Welfare philosophy.
Evolución de los retrotransposones con LTRs del grupo "TY3-GYPSY" en los genomas de "Anopheles Gambiae, Aedes Aegypti y Drosophila Melanogaster"

Anopheles gambiae es el principal vector del protozoo Plasmodium falciparum en Africa y es uno de los vectores de la Malaria mas eficientes en el mundo. La Malaria, considerada la enfermedad parasitica mas importante en el mundo, es responsable de 500 millones de enfermos y de hasta 2.7 millones de muertes cada ano, mas del 90% de los cuales ocurren en el Africa subsahariana (Breman, Egan & Keusch, 2001). Por todos nosotros es conocido, en mayor o menor grado, el interes sanitario que supondria disponer de un mayor conocimiento sobre cualquier aspecto relacionado con la biologia de este insecto y, teniendo en cuenta que nos encontramos en la ya denominada Era de la Genomica, era de esperar que el genoma de Anopheles gambiae fuera uno de los primeros genomas eucariotas en ser secuenciado completamente (Holt et al., 2002).
Nonlinear Aspects of the Climate Response to Greenhouse Gas and Aerosol Forcing

Abstract In a series of equilibrium experiments the climate response to present-day radiative forcings of anthropogenic greenhouse gases and aerosol particles is calculated. The study was performed with a model system consisting of the ECHAM4 atmospheric general circulation model coupled to a slab ocean and thermodynamic sea ice model. The model includes transport of the relevant chemical constituents, a sulfur chemistry model that calculates sulfate production in the gas and aqueous phase, and an aerosol model that accounts for source and sink processes. The aerosol cycle, the hydrological cycle, and the atmospheric dynamics are fully interactive. The climate response to aerosol forcing is not just a mirror image of the response to greenhouse forcing. This applies to the temperature changes, which are regionally more uniform for greenhouse forcing than for aerosol forcing as is already well known, and, in particular, to the hydrological cycle: the global hydrological sensitivity (Δprecip/Δtemp) to a 1-K .
Efficacy of genetic transformation of E.coli field and reference (ATCC 8739) strains at different concentrations of CaCl2 for creation of Gene libraries

The importance of genetic transformation in various fields of biological research, and especially in the process of gene libraries formation, is very important. It has been proven by numerous studies that during the phase of obtaining competent cells, Ca2+ ions neutralize the electrostatic repulsion of membrane proteins and DNA of the bacterial cell, thereby stimulating the introduction of foreign DNA into the membrane pores. Our research aimed to elucidate the maximum efficiency of transformation in field and ATCC 8739 reference strains of E.coli at 0.05; 0.1 and 0.15 M concentrations of CaCL2. Microbiological, molecular-biological modern methods were used in the experimental studies. From the research results, it became evident that the efficiency of genetic transformation increases with the addition of concentration of CaCL2 and reaches the maximum at 0.1 M. Among the studied strains of E.coli, at 0.05 and 0.1 M concentrations of CaCL2, the highest efficiency was recorded in the field strain. At a 0.15 M concentration of CaCL2, the transformation efficiency in the field and reference strains is highly variable due to the size of the genomic DNA of the internalizing bacteria and the number of restriction sites.
Performance Evaluation of the Regional Seismograph Network in Northeast British Columbia, Canada, for Monitoring of Induced Seismicity

An important factor in mitigation of seismic hazard from induced seismicity is properly established seismic networks suitable for consistent identification of small‐to‐moderate events (magnitudes less than four). Here, we evaluate the performance of the newly established regional broadband seismic network in northeast British Columbia, Canada. The seismic network was designed for monitoring of induced seismicity due to oil and gas operations related to hydraulic fracturing and fluid injection in the region. We use regional and local earthquake catalogs for the period 1985–2015 to analyze magnitude of completeness and epicentral uncertainty. We also perform a theoretical assessment of minimum detectable magnitude across the study region based on analysis of ambient noise and simulated ground motions. From the frequency–magnitude distribution of the reported events in the regional earthquake catalog, the magnitude of completeness has decreased ∼1 magnitude unit from ∼3 in the periods 1985–2013 to ∼2 in the period 2013–2015 as a result of the establishment of new stations. The minimum detectable magnitude in the region is 1.6–2.6 based on the signal‐to‐noise ratio (SNR) of 10 and higher at four or more stations. By comparing the regional and dense array catalogs, we determine that the error in epicentral location in well‐constrained areas by seismic stations is below 3 km in both east–west and north–south directions. However, location uncertainties can be up to 10 km in the east–west direction in areas where the current regional network is sparse. The magnitude detection threshold in the Montney Play, where most of the current oil and gas activities are taking place, can be further reduced by up to 1 magnitude unit with the addition of four new stations.
Progression and Challenges of IoT in Healthcare: A Short Review

Smart healthcare, an integral element of connected living, plays a pivotal role in fulfilling a fundamental human need. The burgeoning field of smart healthcare is poised to generate substantial revenue in the foreseeable future. Its multifaceted framework encompasses vital components such as the Internet of Things (IoT), medical sensors, artificial intelligence (AI), edge and cloud computing, as well as next-generation wireless communication technologies. Many research papers discuss smart healthcare and healthcare more broadly. Numerous nations have strategically deployed the Internet of Medical Things (IoMT) alongside other measures to combat the propagation of COVID-19. This combined effort has not only enhanced the safety of frontline healthcare workers but has also augmented the overall efficacy in managing the pandemic, subsequently reducing its impact on human lives and mortality rates. Remarkable strides have been made in both applications and technology within the IoMT domain. However, it is imperative to acknowledge that this technological advancement has introduced certain challenges, particularly in the realm of security. The rapid and extensive adoption of IoMT worldwide has magnified issues related to security and privacy. These encompass a spectrum of concerns, ranging from replay attacks, man-in-the-middle attacks, impersonation, privileged insider threats, remote hijacking, password guessing, and denial of service (DoS) attacks, to malware incursions. In this comprehensive review, we undertake a comparative analysis of existing strategies designed for the detection and prevention of malware in IoT environments.
Systematic Literature and Expert Review of Agile Methodology Usage in Business Intelligence Projects

Background: Agile methodology is known for delivering effective projects with added value within a shorter timeframe, especially in Business Intelligence (BI) system which is a valuable tool for informed decision-making. However, identifying impactful elements for successful BI implementation is complex due to the wide range of Agile attributes. Objective: This research aims to systematically review and analyze the integration of BI within Agile methodology, providing valuable guidance for future projects implementation, enhancing the understanding of effective application, and identifying influential factors. Methods: Based on the Kitchenham method, 19 papers were analyzed from 288 papers, sourced from databases like Scopus, ACM, IEEE, and others published in 2016-2022. Meanwhile the extracted key factors impacting agile BI implementation were validated by qualified expert. Results: Agile was discovered to provide numerous benefits to BI projects by promoting flexibility, collaboration, and rapid iteration for enhanced adaptability, while effectively addressing challenges including those related to technology, management, and skills gaps. In addition, Agile methods, including tasks such as calculating cycle time, measuring defect backlogs, mapping code ownership, and engaging end users, offered practical solutions. The advantages included adaptability, success, value enhancement, cost reduction, shortened timelines, and improved precision. The research additionally considered other critical Agile elements such as BI tools, Agile Practices, Manifesto, and Methods, thereby enhancing insights for successful implementation. Conclusion: In conclusion, the research outlined Agile BI implementation into seven key factor groups, validated by qualified expert, providing guidance for BI integration and practices, and establishing a fundamental baseline for future applications. Keywords: Agile Methodology, Business Intelligence (BI), Expert Judgement, Kitchenham, Systematic Literature Review (SLR)
Design of routing protocol for enhancing quality of service in wireless ad hoc and sensor netw ork: LEQA

Wireless sensor networks (WSNs) are now adopting mobile sensors due to their increased popularity in research and industry. To enhance WSNs' performance, mobility can be utilized to gather data. But, if the collector's route is fixed and movement is not manageable, current quality of service (QoS) strategies and protocols are ineffective in achieving timely data delivery while maintaining energy efficiency. In the real world, WSN networks use both actuator - actuator and sensor - actuator coordination. To conserve energy in communicati on tasks with heavy traffic and high volume, sensors/actuators can be relocated to desired locations. This study introduces a routing protocol that optimizes delivery latency and energy conservation in WSNs. The proposed latency, energy, and quality of ser vice aware (LEQA) protocol uses a cooperative approach to track the sink and coordinate communication between sensors and actuators. Each sensor schedules its time division multiple access (TDMA) to improve QoS metrics such as low energy consumption, low l atency, or packet loss. It also addresses sensor - actuator coordination and proposes a data communication protocol for efficient and fast communication with actuator nodes. This reduces energy consumption and minimizes latency.
Environmental management and firm performance on firm value moderated by good corporate governance

This research aims to analyze the influence of environmental management and firm performance on firm value, which is moderated by good corporate governance, which is proxied by board size and independent commissioners. The research design is quantitative research with the title "The Influence of Environmental Management and Firm Performance on Firm Value Moderated by Good Corporate Governance". The data source is secondary data collected from the IDX (Indonesian Stock Exchange) website to access financial report data of mining sector manufacturing companies, for the period 2017 - 2022. The population of this research is mining sector companies listed on the IDX for the 2017-2022 period. The sampling technique used in this research was purposive sampling. The results show that there is no direct influence from ISO certification on ROA (Return on Assets). There is a significant positive effect of firm value from the environmental management and firm performance variable, moderated by board size. However, the presence of independent commissioners does not moderate the effect of ISO and ROA on firm value. This means that the existence of directors can moderate the implementation of ISO 14001 on company value.
User-Guided Enhancements to a Technology-Facilitated Resilience Program to Address Opioid Risks Following Traumatic Injury in Youth: Qualitative Interview Study

Background Youth with traumatic injury experience elevated risk for behavioral health disorders, yet posthospital monitoring of patients’ behavioral health is rare. The Telehealth Resilience and Recovery Program (TRRP), a technology-facilitated and stepped access-to-care program initiated in hospitals and designed to be integrated seamlessly into trauma center operations, is a program that can potentially address this treatment gap. However, the TRRP was originally developed to address this gap for mental health recovery but not substance use. Given the high rates of substance and opioid use disorders among youth with traumatic injury, there is a need to monitor substance use and related symptoms alongside other mental health concerns. Objective This study aimed to use an iterative, user-guided approach to inform substance use adaptations to TRRP content and procedures. Methods We conducted individual semistructured interviews with adolescents (aged 12-17 years) and young adults (aged 18-25 years) who were recently discharged from trauma centers (n=20) and health care providers from two level 1 trauma centers (n=15). Interviews inquired about reactions to and recommendations for expanding TRRP content, features, and functionality; factors related to TRRP implementation and acceptability; and current strategies for monitoring patients’ postinjury physical and emotional recovery and opioid and substance use. Interview responses were transcribed and analyzed using thematic analysis to guide new TRRP substance use content and procedures. Results Themes identified in interviews included gaps in care, task automation, user personalization, privacy concerns, and in-person preferences. Based on these results, a multimedia, web-based mobile education app was developed that included 8 discrete interactive education modules and 6 videos on opioid use disorder, and TRRP procedures were adapted to target opioid and other substance use disorder risk. Substance use adaptations included the development of a set of SMS text messaging–delivered questions that monitor both mental health symptoms and substance use and related symptoms (eg, pain and sleep) and the identification of validated mental health and substance use screening tools to monitor patients’ behavioral health in the months after discharge. Conclusions Patients and health care providers found the TRRP and its expansion to address substance use acceptable. This iterative, user-guided approach yielded novel content and procedures that will be evaluated in a future trial.
Multi-cue Integration Object Tracking Based on Blocking

Aiming at object occlusions and appearance changes and other issues under complex environment, a new tracking method of multi-cue integration particle filter based on blocking is proposed. Based on fragment the method using color, texture and edge cues integration constructs particle weights updating scheme, and according to the probabilities of which varied information belongs to the object or to the background region, distinguishes appearance changes and occlusions, then the local template updating is applied and the stability of tracking is improved. In order to verify the performance and effectiveness of this method, the experiments use the indoor and outdoor test videos which contained the light changes, occlusions, and the appearance changes of objects. The experimental results showed that the method had strong robustness and high tracking accuracy.
Chac1 silencing mitigates hemorrhagic shock-induced intestinal injury by inhibiting oxidative stress and ferroptosis

Hemorrhagic shock (HS) is a common and significant cause of mortality and morbidity, often resulting in structural damage and dysfunction of the intestines. ChaC glutathione-specific gamma-glutamylcyclotransferase 1 (Chac1) has been reported to be involved in the regulation of oxidative stress and ferroptosis in mammals. Herein, we investigate the effects of Chac1 on HS-induced intestinal injury induced by HS both in vitro and in vivo. Sprague-Dawley rat model with HS was established, and our investigations showed upregulation of the mRNA and protein levels of Chac1 in the model’s ileum tissues. Histopathological analysis revealed that knockdown of Chac1 attenuated the intestinal injury induced by HS. Depletion of Chac1 also reduced the increase in intestinal fatty acid binding protein (I-FABP) concentration. Immunofluorescence staining indicated that silencing Chac1 significantly suppressed the downregulation of occludin and zonula occludens-1 (ZO-1). HS-induced changes in lipid peroxidation (LPO), malondialdehyde (MDA), and glutathione (GSH) levels were reversed in the absence of Chac1, suggesting that downregulation of Chac1 alleviated HS-induced oxidative stress. Additionally, HS led to a decrease in glutathione peroxidase 4 (Gpx4) and ferritin heavy chain 1 (Fth1) expression, along with an increase in ferrous ion (Fe2+) concentration. Knockdown of Chac1 significantly inhibited ferroptosis by increasing Gpx4 and Fth1 expression while reducing the Fe2+ concentration. In vitro experiments using the rat small intestine crypt epithelial cells (IEC-6) demonstrated that depletion of Chac1 suppressed oxidative stress and ferroptosis induced by hypoxia/reoxygenation (H/R). In conclusion, our study provides evidence that downregulation of Chac1 mitigates HS-induced intestinal injury by inhibiting oxidative stress and ferroptosis.
User Association and Load Balancing Based on Monte Carlo Tree Search

The user association algorithm for 5G ultra-dense heterogeneous networks (UD-HetNets) comprising multi-tier base stations is becoming increasingly complex. In UD-HetNets, small base stations (SBSs) play an important role in offloading data traffic of user equipments (UEs) requiring high data rate from macro base stations (MBSs) to enhance the quality of services (QoS) of them. However, the traditional cell range expansion (CRE) scheme poses a risk of congestion in certain SBSs and the emergence of UEs monopolizing resources in less congested SBSs, which causes SBS load imbalance and decreases fairness performance. At the same time, determining the optimal user association result for load balancing, considering all possible combinations of associations between UEs and SBSs, leads to prohibitively high computational complexity. To obtain a near-optimal user association solution with manageable computational complexity, in this paper, we propose a heuristic algorithm based on Monte Carlo tree search (MCTS) for user association in UD-HetNet. We model the user association problem as a combinatorial optimization problem and provide a detailed design of the MCTS steps to solve this NP-hard problem. The MCTS algorithm obtains a near-optimal UEs-SBSs combination in terms of load balancing and maximizes the fairness of the overall network. This combination derived from the proposed algorithm aims to achieve load balancing among SBSs and mitigate resource monopolization among UEs. The simulation results show that the proposed algorithm outperforms conventional user association schemes in terms of fairness. As a result, compared to traditional CRE schemes, the proposed method can provide good performance to the UEs receiving data rates of the bottom 50%. Furthermore, the gap between optimal and heuristic solutions does not exceed 4%. Due to its manageable computational complexity, the proposed algorithm can be implemented as an xApp on the O-RAN near-real-time RAN intelligent controller (RIC).