Miracle-dz/UniFAR-FTUs huggingface dataset:
Segmental expression of the T‐box transcription factor, Tbx2, during early somitogenesis

Tbx2 belongs to the T‐box transcription factor gene family and is expressed in a variety of tissues and structures throughout development, although not all expression domains have been thoroughly described. Two areas of segmented expression along the rostral‐caudal axis of E10.5–11.5 embryos were identified as inter‐somitic vessels and dorsal root ganglia. In addition, Tbx2 expression is observed during somitogenesis beginning at E9.5, both in the posterior half of prospective somites and in a progressively restricted pattern in recently formed somites. Developmental Dynamics 235:3080–3084, 2006. © 2006 Wiley‐Liss, Inc.
Corticospinal Excitability Modulation During Action Observation

This study used the transcranial magnetic stimulation/motor evoked potential (TMS/MEP) technique to pinpoint when the automatic tendency to mirror someone else's action becomes anticipatory simulation of a complementary act. TMS was delivered to the left primary motor cortex corresponding to the hand to induce the highest level of MEP activity from the abductor digiti minimi (ADM; the muscle serving little finger abduction) as well as the first dorsal interosseus (FDI; the muscle serving index finger flexion/extension) muscles. A neuronavigation system was used to maintain the position of the TMS coil, and electromyographic (EMG) activity was recorded from the right ADM and FDI muscles. Producing original data with regard to motor resonance, the combined TMS/MEP technique has taken research on the perception-action coupling mechanism a step further. Specifically, it has answered the questions of how and when observing another person's actions produces motor facilitation in an onlooker's corresponding muscles and in what way corticospinal excitability is modulated in social contexts.
ARTS: Accelerated Ray-Tracing System

In this article we propose algorithms that address the two basic problems encountered in generating continuous-tone images by ray tracing: speed and aliasing. We examine previous approaches to the problem and then propose a scheme based on the coherency of an auxiliary data structure imposed on the original object domain. After investigating both simple spatial enumeration and a hybrid octree approach, we developed 3DDDA, a 3D line generator for efficient traversing of both structures. 3DDDA provides an order of magnitude improvement in processing speed compared to other known ray-tracing methods. Processing time is found to be virtually independent of the number of objects involved in the scene. For large numbers of objects, this method actully becomes faster than scan-line methods. To remove jags from edges, a scheme for identifying edge orientation and distance from pixel center to true edge has been implemented. The time required for antialiasing depends on the total length of the edges encountered, but it is normally only a fractional addition to the time needed to produce the scene without antialiasing.
A probabilistic framework for global localization with segmented planes

This paper proposes a novel approach to global localization using high-level features. The new probabilistic framework enables to incorporate uncertain localization cues into a probability distribution that describes the likelihood of the current robot pose. We use multiple triplets of planes segmented from RGB-D data to generate this probability distribution and to find the robot pose with respect to a global map of planar segments. The algorithm can be used for global localization with a known map or for closing loops with RGB- D data. The approach is validated in experiments using the publicly available NYUv2 RGB-D dataset and our new dataset prepared for testing localization on plane-rich scenes.
Political Economy in the Eighteenth Century: Popular or Despotic? The Physiocrats Against the Right to Existence

Control over food supply was advanced in the kingdom of France in the Eighteenth century by Physiocrat economists under the seemingly advantageous label of 'freedom of grain trade'. In 1764 these reforms brought about a rise in grain prices and generated an artificial dearth that ruined the poor, some of whom died from malnutrition. The King halted the reform and re-established the old regime of regulated prices; in order to maintain the delicate balance between prices and wages, the monarchy tried to limit speculation in subsistence goods and achieved some success in regulating the provisioning of public markets. Le Mercier de la Riviere concluded that executing these reforms required more effective political control. After 1774 the new king gave the Physiocratic reforms a second chance, reforming property rights and establishing an aristocracy of the landed rich. Again, this led to price hikes and as a result so-called 'popular emotions' erupted. Turgot ordered military intervention to dispel the protesters, marking a first rupture between the monarchy and the people over speculation on subsistence. Turgot's experiment failed and he was dismissed, but the Physiocracy had discovered that the market in subsistence offered new opportunities for economic power under the misleading legitimacy of 'economic laws'. Turgot's followers, Dupont de Nemours and Condorcet, continued to develop this 'theory' that was later translated into a 'scientific language' that ultimately asserted the autonomy of the economic sphere and its alleged independence from ethics and politics. The paper examines the continuity of events through the six great jacqueries and the French Revolution, including the all- important agrarian reform that ensued after 1792. Robespierre's concept of 'popular political economy' is analysed and compared with the notion of unfettered private property rights that lies at the heart of neoliberalism.
Effects of Load on Peak Power Output Fatigue During the Bench Throw

Abstract Boffey, D, Sokmen, B, Sollanek, K, Boda, W, and Winter, S. Effects of load on peak power output fatigue during the bench throw. J Strength Cond Res 33(2): 355–359, 2019—The ability to create power is an important variable for athletic success. No study to date has compared peak power output (PPO) fatigue across multiple sets and with different loads with the bench throw. This study aimed to begin the process of establishing empirical upper-body power training guidelines for moderately strong athletes by determining how load (30, 45, and 60% 1 repetition maximum [1RM]) affects PPO (Watts) dropoff during 3 sets of 10 repetitions of the bench throw. Ten resistance-trained male volunteers ([mean ± SD]: age 20.58 ± 1.36 years, height 176.05 ± 9.09 cm, body mass 78.65 ± 9.93 kg, bench press 1RM 99.79 ± 18.52 kg) performed 3 sets of 10 repetitions of the bench throw with one of the 3 loads during 3 weekly sessions. A Humac 360 device collected concentric phase PPO data during each repetition. The data were analyzed using one-way (treatment) and 2-way (treatment × time) repeated-measures analysis of variance. A significant decrease in PPO was observed during repetitions 5–7 at 30%, 3–4 at 45%, and 2–3 at 60% 1RM. Based on the results of this study, coaches who want to maximize power should potentially keep sets of upper-body plyometrics within these repetition ranges. The authors recommend that moderately strong athletes perform the bench throw on a Smith machine at 45% or 60% 1RM to produce high PPO over multiple sets.
Parallel Read-Alouds: A Bilingual Repeated Read-Aloud and Retelling Intervention for Kindergarten ELLs

Teachers working with young ELLs at risk for literacy underachievement lack research-based practices to maximize the use of picture book read-alouds to accelerate language comprehension outcomes. This study investigated the effects of 8-22 weeks of small group, bilingual repeated read-aloud and retelling intervention, the parallel readaloud intervention, on Vietnamese ELL kindergarteners’ retelling skills, focusing on the use of story grammar elements and language complexity and productivity. The study was conducted using a multiple-baseline single subject design with 5 subjects. Students’ growth in the overall quality of narrative retelling was assessed weekly using the Test of Narrative Retell (TNR) and their growth in language complexity was simultaneously assessed by transcribing the weekly retell samples to calculate scores for number of diverse words (NDW) and mean length of utterance (MLU) using the Systematic Analysis of Language Transcripts (SALT) software. The results supported a moderate intervention effect for overall retelling scores on the TNR and for NDW, which were maintained across most subjects after four weeks without intervention. The major implications of this study relate to differentiating instruction for young ELLs with low English oral proficiency by offering bilingual, repeated read-aloud interventions and Darci Melchor – University of Connecticut, 2015 using progress monitoring assessments to accelerate their growth with language comprehension in English.
PYRIDOXINE‐DEPENDENT SEIZURES: DEMOGRAPHIC, CLINICAL, MRI AND PSYCHOMETRIC FEATURES, AND EFFECT OF DOSE ON INTELLIGENCE QUOTIENT

A regional population‐based survey identified six patients with pyridoxine dependency. Four presented on the first day of life and the other two at 1 and 8 months of age. Apart from multiple seizure types, other presenting features included jitteriness; encephalopathy, at first thought to be hypoxic‐ischaemic; hepatomegaly, and abdominal distension with bilious vomiting. Later problems included break‐through fits with fever; transient visual agnosia; squint; severe articulatory apraxia; motor delay with later dyspraxia; macrocephaly. and post‐haemorrhagic hydrocephalus. Magnetic resonance imaging showed variable structural abnormalities in all the early onset cases. Psychometric assessment revealed a stereotyped pattern of intelligence scale subtest scores, with a specific impairment of expressive verbal ability. In a prospective open study over one year, an. ‐ increased dose of pyridoxine was associated with an improvement in IQ, particularly in performance subtests. Pyridoxine dependency is more common than has been thought. It has a wider range of clinical features than the classical neonatal seizures and causes specific impairments of higher function, some of which may be reversible. The dosage of pyridoxine should be optimal for IQ as well as seizure control.
The Segregation and Integration of Distinct Brain Networks and Their Relationship to Cognition

A critical feature of the human brain that gives rise to complex cognition is its ability to reconfigure its network structure dynamically and adaptively in response to the environment. Existing research probing task-related reconfiguration of brain network structure has concluded that, although there are many similarities in network structure during an intrinsic, resting state and during the performance of a variety of cognitive tasks, there are meaningful differences as well. In this study, we related intrinsic, resting state network organization to reconfigured network organization during the performance of two tasks: a sequence tapping task, which is thought to probe motor execution and likely engages a single brain network, and an n-back task, which is thought to probe working memory and likely requires coordination across multiple networks. We implemented graph theoretical analyses using functional connectivity data from fMRI scans to calculate whole-brain measures of network organization in healthy young adults. We focused on quantifying measures of network segregation (modularity, system segregation, local efficiency, number of provincial hub nodes) and measures of network integration (global efficiency, number of connector hub nodes). Using these measures, we found converging evidence that local, within-network communication is critical for motor execution, whereas integrative, between-network communication is critical for working memory. These results confirm that the human brain has the remarkable ability to reconfigure its large-scale organization dynamically in response to current cognitive demands and that interpreting reconfiguration in terms of network segregation and integration may shed light on the optimal network structures underlying successful cognition. SIGNIFICANCE STATEMENT The dynamic nature of the human brain gives rise to the wide range of behaviors and cognition of which humans are capable. We collected fMRI data from healthy young adults and measured large-scale functional connectivity patterns between regions distributed across the entire brain. We implemented graph theoretical analyses to quantify network organization during two tasks hypothesized to require different combinations of brain networks. During motor execution, segregation of distinct networks increased. Conversely, during working memory, integration across networks increased. These changes in network organization were related to better behavioral performance. These results underscore the human brain's ability to reconfigure network organization selectively and adaptively when confronted with changing cognitive demands to achieve an optimal balance between segregation and integration.
Evaluation of Glycemic Control Metrics for Intensive Care Unit Populations

Glycemic control is an important quality indicator in the management of intensive care unit patients. Tight glycemic control and/or insulin infusion protocols may reduce complications and improve outcomes in certain intensive care unit patients. Unfortunately, a consistent method of describing glycemic control has not been used for this population. A standardized metric is needed to adequately evaluate quality performance as well as interpret and apply the literature. The current glycemic control metrics such as mean, median, mean morning, hyperglycemic index, and time-weighted averages will be analyzed. The complexities associated with reporting glycemic control data for national quality performance will also be reviewed. The goal is to facilitate and propose the selection of a glycemic control metric for critically ill patients that can be universally applied in clinical trials and quality performance standards. (Am J Med Qual 2009;24:310-320)
A New Approach of Presenting Universal Reversible Gate in Nanoscale

Quantum dot Cellular Automata (QCA) is an emerging digital logic representation techniques and one of the possible alternatives to Complementary Metal–Oxide–Semiconductor (CMOS) technology. It satisfies attractive circuit components of smaller size and low power dissipation of new circuit design technologies. Quantum dots are nano architecture and it works based on columbic interaction between two electrons. This paper presents Universal Reversible Gate based on QCA logic gates. For simulating and verifying the proposed gate QCA Designer a familiar simulation and verification tools has been employed. Correctness of the proposed circuit revealed by the simulated output. This paper also presents the VHDL Code of this circuit.
Developing a sense of belonging in the classroom: community college students taking courses on a four-year college campus

Abstract In 2005, Louisiana implemented the Master Plan for Public Postsecondary Education: 2001 (Board of Regents, State of Louisiana, 2001) to restructure its higher education system in an effort to provide its citizens with high quality postsecondary educational choices. This restructuring forced its two-year and four-year institutions to redesign their developmental education programs. Subsequently, several two-year institutions partnered with four-year institutions to offer developmental courses on the four-year college campuses. However, little is known about the experiences of the two-year students in these settings, especially as they relate to classroom experiences. Thus, this phenomenological study explored the academic-social experiences of 20 students enrolled at the two-year college and taking classes at a four-year institution. The study was done in hopes of garnering a better understanding of factors that impact integration and persistence. This article focuses on how the students developed a sense of belonging in the classroom, and it makes connections as to how these students’ experiences may impact integration and persistence and/or transferability to four-year institutions. Additionally, recommendations for research and practice are presented.
PITTCULT: Recommender System using Trusted Human Network

As information on the Web continues to increase, available on more and more sites, it is increasingly important to be able to collect information in one place and filter out unnecessary information for users. PITTCULT is to share and recommend cultural event information in the Pittsburgh area. This system basically utilizes human psychology to conform to opinions of friends. When people go to a music concert or exhibition, they commonly ask their friends ' opinions, and invite them to go along. Centered on this trusted human network, users can recommend items to their friends and rate their friends ' taste about a certain genre of cultural events. As a popular recommendation technology, collaborative filtering-based recommendation (CF) is designed to find like-minded peers and is known to recommend more diverse and serendipitous recommendations. It works well in a domain where contents are not easily comparable, like music, movies, jokes and cultural events (Schafer, et al., 2007). However, CF has a data sparsity problem. If the users ' ratings are relatively fewer than the number of items, there will be too little overlap among users to make recommendation. In addition, there is cold-start problem for new users who have no or insufficient ratings (Massa & Avesani, 2007; Schafer, et al., 2007). Another problem of CF is created by ad-hoc users. Users possessing malicious intentions can harness others ' ratings to make a profit or distort the system
Cancer Pain Management in Resource-Limited Settings: A Practice Review

Pain in cancer is a common and burdensome symptom with different causes but in a significant number of cases it is undiagnosed and undertreated because of lack of skills for its assessment. Pain has significant negative impact on the patient and, therefore, it needs to be managed urgently and appropriately. In resource-limited settings, there are several barriers and challenges to pain management but even in these circumstances pain can be well managed with planned and innovative use of resources and if the World Health Organization public health system approach is used to ensure opioid availability.
Mutants of Tn3 resolvase which do not require accessory binding sites for recombination activity

Tn3 resolvase promotes site‐specific recombination between two res sites, each of which has three resolvase dimer‐binding sites. Catalysis of DNA‐strand cleavage and rejoining occurs at binding site I, but binding sites II and III are required for recombination. We used an in vivo screen to detect resolvase mutants that were active on res sites with binding sites II and III deleted (that is, only site I remaining). Mutations of amino acids Asp102 (D102) or Met103 (M103) were sufficient to permit catalysis of recombination between site I and a full res, but not between two copies of site I. A double mutant resolvase, with a D102Y mutation and an additional activating mutation at Glu124 (E124Q), recombined substrates containing only two copies of site I, in vivo and in vitro. In these novel site I×site I reactions, product topology is no longer restricted to the normal simple catenane, indicating synapsis by random collision. Furthermore, the mutants have lost the normal specificity for directly repeated sites and supercoiled substrates; that is, they promote recombination between pairs of res sites in linear molecules, or in inverted repeat in a supercoiled molecule, or in separate molecules.
Maximizing LTE Capacity in Unlicensed Bands (LTE-U/LAA) While Fairly Coexisting With 802.11 WLANs

We propose a channel access mechanism that allows Long Term Evolution (LTE) to operate in the 5-GHz unlicensed band (LTE-U/LAA) and fairly coexist with 802.11 Wireless Local Area Networks (WLANs). The proposed mechanism is compliant with listen before talk, and it can be configured to maximize the channel time used by the LTE-U stations while fairly coexisting with the 802.11 WLANs. That is, an LTE-U station will not affect the throughput of a WLAN more than if it were an 802.11 station.
Millimetre continuum observations of southern massive star formation regions. I. SIMBA observations of cold cores

We report the results of a 1.2-mm continuum emission survey toward 131 star-forming complexes suspected of undergoing massive star formation. These regions have previously been identified as harbouring a methanol maser and/or a radio continuum source [ultracompact (UC) H II region], the presence of which is in most instances indicative of massive star formation. The 1.2-mm emission was mapped using the SIMBA instrument on the 15-m Swedish ESO Submillimetre Telescope (SEST). Emission is detected toward all of the methanol maser and UC H II regions targeted, as well as towards 20 others lying within the fields mapped, implying that these objects are associated with cold, deeply embedded objects. Interestingly, there are also 20 methanol maser sites and nine UC H II regions within the fields mapped which are devoid of millimetre continuum emission. In addition to the maser and UC H II regions detected, we have also identified 253 other sources within the SIMBA maps. All of these (253) are new sources, detected solely from their millimetre continuum emission. These ‘mm-only’ cores are devoid of the traditional indicators of massive star formation, (i.e. methanol/OH maser, UC H II regions or IRAS point sources). At least 45 per cent of these mm-only cores are also without mid-infrared Mid-course Space Experiment (MSX) emission. The ‘mm-only’ core may be an entirely new class of source that represents an earlier stage in the evolution of massive stars, prior to the onset of methanol maser emission. Or, they may harbour protoclusters which do not contain any high-mass stars (i.e. below the H II region limit). In total, 404 sources are detected, representing four classes of sources which are distinguished by the presence of the different combination of associated tracer/s. Their masses, estimated assuming a dust temperature of 20 K and adopting kinematic distances, range from 0.5 × 10 1 to 3.7 × 10 4 M� , with an average mass for the sample of 1.5 × 10 3 M� . The H2 number density (nH2 )o fthe source sample ranges from 1.4 × 10 3 to 1.9 × 10 6 cm −3 , with an average of 8.7 × 10 4 cm −3 . The average radius of the sample is 0.5 pc. The visual extinction ranges from 10 to 500 mag with an average of 80 mag, which implies a high degree of embedding. The surface density (� )v aries from 0.2 to 18.0 kg m −2 with an average of 2.8 kg m −2 . Analysis of the millimetre-only sources shows that they are less massive ( ¯
Larvicidal toxicity of Japanese Bacillus thuringiensis against the mosquito Anopheles stephensi

Japanese isolates of Bacillus thuringiensis were screened for larvicidal activity against the mosquito Anopheles stephensi, the urban malaria vector of the Indian subcontinent. Among more than 30 strains identified, larvicidal activity causing >80% mortality in 72 h was demonstrated for 41/1449 (2.8%) isolates. The majority of strains and isolates (97.2%) exhibited little or no larvicidal activity. Anopheles‐active strains belonged to more than 12 H serotypes, especially H3ade (serovar fukuokaensis) and H44 (serovar higo). SDS‐PAGE profiles of inclusion proteins showed 4 distinct types among 6 active strains examined. The most active Japanese isolates were H20 strain 89‐T‐34‐14 (LC50 4.4 μg/ml) and H44 serovar higo strain 74‐E‐45‐24 (LC50 7.6 μg/ml), respectively, 13‐fold and 23‐fold less active than the international standard H14 serovar israelensis (LC50 0.33 μg/ml).