Miracle-dz/UniFAR-FTUs huggingface dataset:
Identification of Key Genes from the Visceral Adipose Tissues of Overweight/Obese Adults with Hypertension through Transcriptome Sequencing

Overweight and obese (OW/OB) adults are at increased risk of hypertension due to visceral adipose tissue (VAT) inflammation. In this study, we explored gene level differences in the VAT of hypertensive and normotensive OW/OB patients. VAT samples obtained from six OW/OB adults (three hypertensive, three normotensive) were subjected to transcriptome sequencing analysis. Gene set enrichment analysis was conducted for all gene expression data to identify differentially expressed genes (DEGs) with |log2 (fold change)| ≥ 1 and q < 0.05. Gene Ontology and Kyoto Encyclopedia of Genes and Genomes functional enrichment analyses were performed on the DEGs, and hub genes were identified by constructing a protein-protein interaction (PPI) network. The proposed hub genes were validated using quantitative real-time PCR in ten other samples from five hypertensive and five normotensive patients. In addition, we performed ROC analysis and Spearman correlation analysis. A total of 84 DEGs were identified between VAT samples from OW/OB patients with and without hypertension, among which 21 were significantly upregulated and 63 were significantly downregulated. Bioinformatics analysis revealed that spleen function was related to hypertension in OW/OB adults. Meanwhile, PPI network analysis identified the following top 10 hub genes: CD79A, CR2, SELL, CD22, IL7R, CCR7, TNFRSF13C, CXCR4, POU2AF1, and JAK3. Through qPCR verification, we found that CXCR4, CD22, and IL7R were statistically significant. qPCR verification suggested that RELA was statistically significant. However, qPCR verification indicated that NFKB1 and KLF2 were not statistically significant. These hub genes were mainly regulated by the transcription factor RELA. The AUC of ROC analysis for CXCR4, IL7R, and CD22 was 0.92. What is more, VAT CXCR4 and CD22 were positively related to RELA relative expression levels. Taken together, our research demonstrates that CXCR4, IL7R, and CD22 related to VAT in hypertensive OW/OB adults could serve as future therapeutic targets.
A FEASIBILITY STUDY EXPLORING THE EFFICACY OF COGNITIVE REHABILITATION THERAPY FOR PAEDIATRIC HIV IN RURAL SOUTH AFRICA: A FOCUS ON SUSTAINED ATTENTION

Despite advances in combination antiretroviral therapy (cARTs), children in Sub-Saharan Africa continue to experience neurocognitive deficits due to the virus crossing the blood-brain barrier (BBB). Based on the principles of neuroplasticity, our study sought to investigate the feasibility of introducing a pencil and paper cognitive rehabilitation tool called Brainwave-R, to ameliorate the effects of HIV neurocognition amongst children from a low socioeconomic background in rural South Africa. Five HIV positive and six HIV negative children were assigned to either an experimental or control group. The experimental group underwent two months of cognitive rehabilitation therapy to remediate sustained attention, using Brainwave-R, whereas the noncontact control group took part in placebo activities. Sustained attention measures were taken before and after the intervention training sessions, using a sustained attention subtest. The control group later received cognitive intervention three months following the conclusion of the research study. A Mann Whitney U Test revealed that the experimental group (Mdn=38.50) did not differ significantly from the control group (Mdn=37.00) after the cognitive rehabilitation intervention, U= 12.00, z= -. 55, p= 0.66, r= -0.17. A Wilcoxon Signed Rank Test found that there was a significant improvement from pretest scores (Mdn=31.00) to post test scores (Mdn=38.00) following the rehabilitation for HIV positive participants in the sample, T=15.00, z = -2.02, p= 0.04, r= -0.90. The findings of our study raise the feasibility of a pencil and paper cognitive rehabilitation method to supplement antiretroviral (ARV) therapy in paediatric HIV.
Transient Behavior of a System Composed of Conductive Thin Wire Structures Excited by Harmonic and Lightning Type Signals

The transient response of a system of independent electrodes buried in a semi-infinite conducting medium is studied. Using a simple and versatile numerical scheme written by the authors and based on the Electric Field Integral Equation (EFIE), the effect caused by harmonic signals ranging on frequency from Hz to hundred of MHz, and also by lightning type driving signal striking at a remote point far from the conductors, is extensively studied. The value of the scalar potential appearing on the electrodes as a function of the frequency of the applied signal is one of the variables investigated. Other features such as the input impedance at the injection point of the signal and the Ground Potential Rise (GPR) over the electrode system are also discussed.
Elastic scattering of electrons from Na-like ions

Differential cross sections for elastic scattering of electrons from Al 2+ and Ar 7+ are calculated with the R -matrix method. Using six different sets of coupled states, the convergence is tested against the number of coupled states in the calculation. The converged cross section is analysed in terms of the contributions of the long-range Coulomb force, the short-range electrostatic interaction and the interference of those two. A comparison with the recent measurement at 100 eV for Ar 7+ shows disagreement in the vicinity of a scattering angle of 50°.
Modeling and Dynamic Characteristic Analysis of Space Robotic Cables (Flexible Bodies)

Space robotic cables are responsible for the transmission of load data and power at the end of robots. They are mounted on the space robot bodies and will move along with the robot bodies. In the extreme environment of coupling of high and low temperatures, radiation and microgravity in space, the cables covered by shielding layers will become extremely heavy and hard, while the joints of space robots under strict resource constraints are relatively weak. In the course of motion, heavy cables will cause strong non-linear interference to weak joints of space robots, leading to slow rotation or oscillation of joints at specific locations. Studying the physical characteristics of space cables, the mechanical properties of space robotic joints and their coupling relationship is of great significance to improve the accuracy and stability of space robots' terminal operation. In this paper, the mathematical model of space robotic cables is numerically verified and theoretically analyzed, which proves the validity and rationality of the proposed model.
Statistical Models of Holland Pressure Profile Parameter and Radius to Maximum Winds of Hurricanes from Flight-Level Pressure and H*Wind Data

Abstract In many hurricane risk models the inclusion of the Holland B parameter plays an important role in the risk prediction methodology. This paper presents an analysis of the relationship between B and a nondimensional intensity parameter. The nondimensional parameter includes the strong negative correlation of B with increasing hurricane size [as defined by the radius to maximum winds (RMW)] and latitude as well as a positive correlation with sea surface temperature. A weak positive correlation between central pressure deficit and B is also included in the single parameter term. Alternate statistical models relating B to RMW and latitude are also developed. Estimates of B are derived using pressure data collected during hurricane reconnaissance flights, coupled with additional information derived from the Hurricane Research Division’s H*Wind snapshots of hurricane wind fields. The reconnaissance data incorporate flights encompassing the time period 1977 through 2001, but the analysis was limited to i.
Use Third-Order Quasi-Bandpass Frequency Selection Network to Achieve Low Phase Noise in Microstrip Oscillator

In this letter, a novel microstrip feedback-type oscillator with low phase noise is experimentally demonstrated. To efficiently control the phase noise in the oscillator, a novel frequency selection network (FSN) is proposed, which incorporates two mixed-coupled combline resonators and one incurvate ring resonator to tactfully form a third-order quasi-bandpass response. Correspondingly, three transmission zeros are generated, so that a compromise can be made between the insertion loss and the group delay for optimal operation of the oscillator. For verification, an oscillator example was designed and measured. It works at 2.01 GHz with an output power of 8.32 dBm. The phase noise is as low as −128.59 dBc/Hz at 100-kHz offset, which is the lowest phase noise now among those of $S$ -band microstrip oscillators.
A 32 kW Power-Dense Six-Phase Dual-Interleaved DC–DC Buck-Boost Converter With Three Interphase Transformer

This article presents a power-dense, six-phase dual-interleaved DC-DC Buck-Boost converter for electric/hybrid vehicle applications. This converter uses six hard-switched arms at 75 kHz, three dual-interleaved interphase transformers together with three common inductors and two filter capacitors at the input and output. The steady-state current ripple frequency of the common inductors is twice the switching frequency due to the dual interleaving in the interphase transformers. The resultant ripple current frequency of the input and output filters is six times the switching frequency; size and weight reduction of the passive components are obtained due to this frequency increase. The design and construction details of a 32 kW, 315–385 V supply, SiC-based prototype are presented along with experimental investigation. The prototype converter was successfully operated up to full load with a 350 V output, being the phase currents relatively balanced in the continuous conduction mode without a closed-loop control system. The prototype efficiency is 98 % at full load, being the gravimetric power density 7.56 kW/kg.
Magnetic nanowires for acoustic sensors (invited)

Tiny hairlike sensors or cilia play a very important role in detection for many biological species, including humans. This research took inspiration from the packaging and transduction processes of the inner ear’s cochlea and cilia to design acoustic sensors. Specifically, this work uses nanowires of magnetostrictive materials as artificial cilia to sense acoustic signals. Anodic aluminum oxide (AAO) templates with hexagonal spacings were fabricated using a two-step anodization process as well as nanoimprint assisted self-assembly and were characterized using atomic force microscopy. Patterned microelectrodes were also fabricated at the backside of several templates using photolithography. Ni, Co, and Galfenol (Fe1−xGax0.1⩽x⩽0.25at.%) nanowires were fabricated using electrochemical deposition into nanoporous AAO templates where the pores had various geometries and some had large-area ordering as dictated by nanoimprinting. High aspect ratio nanowires with diameters varying from 10 to 200 nm and lengths up.
Community Solar Operation Strategy for Smart Energy Communities Considering Resource Fairness

This study proposes a community solar operation strategy for smart energy communities (SECs), which comprise members of an energy consumption group, to minimize the electricity bill of its members. When sharing resources within a group, resource distribution is a critical problem, and fairness in resource sharing is the main constraint for operation. The proposed community solar operation is formulated as a mixed-integer liner problem that can be optimally solved using centralized control and future time information. However, obtaining information of a future time is not causal. By decomposing the problem into individual problems that are solved by each member at each decision time, the proposed strategy operates the community solar in a distributed manner with partial information. The simulation results using the real dataset recorded in Korea show that the use of the proposed operation strategy results in a fair distribution of electricity bill savings with a marginal benefit reduction of 10% compared to the optimal operation that requires a centralized control and information on the future time. Moreover, a discussion on the tradeoff between the benefits of electricity bill savings and guarantee of fairness is provided. Based on the results, this study can serve as a reference for the design of community solar operations for SECs.
Reflection of a Plane Transient Electromagnetic Wave From a Cold Lossless Plasma Slab

Reflection of a plane transient electromagnetic wave from a plasma half-space and a plasma slab is considered. The plasma is assumed to be cold and collisions are neglected. Under these assumptions, the Laplace transforms may be inverted exactly, yielding a solution in the form of Bessel function series. The numerical results, for the waveform of the reflected field, exhibit features that are easily related to the plasma frequency of the slab and its thickness.
Pemanfaatan Teknologi Tepat Guna Mesin Abon Kapasitas 25 Kg/ Jam Untuk Peningkatan Produksi UKM Di Sidoarjo

Penulisan tugas akhir ini bertujuan untuk menghasilkan mesin pembuat abon ikan secara otomatis yang dapat memudahkan dalam proses produksi. Yang sebelumnya secara manual dan menguras tenaga pada satu kali produksi, sehingga alat ini diciptakan dari penggabungan tiga fungsi alat menjadi suatu mesin pembuat abon ikan. Mesin pemisah daging dan tulang ikan, tungku pemasakan dan mesin pengering abon/spinner, yang dapat di kontrol secara elektrik tanpa mengeluarkan banyak tenaga dalam proses produksi yang lebih higienis dan efisien waktu yang lebih baik dalam satu kali proses produksi. Mesin ini bekerja memanfaatkan energi dari motor listrik ¾ Hp sebagai sumber penggerak mesin pemisah daging dengan putaran 2840 rpm dan motor ½ Hp dengan putaran 2840 rpm dan mempunyai kapasitas produksi 10 kg/20 menit, pully dan vanbelt sebagai penerus daya ke masing – masing komponen, kompor yang di kontrol secara elektrik, dan pengering abon yang di kontrol sistem elektrik.
A Method for Estimating Longitudinal Change in Motor Skill from Individualized Functional-Connectivity Measures

Pragmatic, objective, and accurate motor assessment tools could facilitate more frequent appraisal of longitudinal change in motor function and subsequent development of personalized therapeutic strategies. Brain functional connectivity (FC) has shown promise as an objective neurophysiological measure for this purpose. The involvement of different brain networks, along with differences across subjects due to age or existing capabilities, motivates an individualized approach towards the evaluation of FC. We advocate the use of EEG-based resting-state FC (rsFC) measures to address the pragmatic requirements. Pertaining to appraisal of accuracy, we suggest using the acquisition of motor skill by healthy individuals that could be quantified at small incremental change. Computer-based tracing tasks are a good candidate in this regard when using spatial error in tracing as an objective measure of skill. This work investigates the application of an individualized method that utilizes Partial Least Squares analysis to estimate the longitudinal change in tracing error from changes in rsFC. Longitudinal data from participants yielded an average accuracy of 98% (standard deviation of 1.2%) in estimating tracing error. The results show potential for an accurate individualized motor assessment tool that reduces the dependence on the expertise and availability of trained examiners, thereby facilitating more frequent appraisal of function and development of personalized training programs.
Quasi-Equilibrium Density Distributions of Small Dust Aggregations in the Solar Nebula

Abstract The rotational velocity of a fluid element around the midplane of the solar nebula increased as dust settled toward the midplane. The Kelvin and Helmholtz instability due to velocity difference of a dust-rich region and a dust-poor region should have occurred and the dust layer became turbulent when the Richardson number decreased below the critical value. Then, dust aggregations stirred up due to turbulent diffusion and were prevented to settle further. In this paper, the sizes of dust aggregations are assumed to be equal to or smaller than the typical radius of chondrules (∼0.3 mm). In this case, even very weak turbulence stirs up dust aggregations. Therefore a dust density distribution is considered to be self regulated so that the Richardson number is nearly equal to the critical value. The quasi-equilibrium dust density distribution is derived analytically by assuming that the Richardson number is equal to the critical value. The derived dust density at the midplane is much smaller than the critical density of the gravitational stability, if the solar composition of dust to gas ratio is assumed. On the other hand, the dust aggregations concentrate around the midplane and the dust layer becomes gravitationally unstable, if more than 97% (at 1 AU from the Sun) of the gaseous components have been dissipated from the nebula, leaving dusty components. Two alternative scenarios of planetesimal formation are proposed: planetesimals were formed by (1) mutual sticking of dust aggregations by nongravitational forces or by (2) gravitational instabilities in the nebula where the dust to gas ratio is much larger than the ratio with solar elemental abundance. Case (2) might be realized due to dissipation of the nebular gas and/or addition of dust by the bipolar outflow. In case (1), chondrule sizes do not indicate the maximum size of dust aggregations in the solar nebula.
Bridging social media content and re-purchasing behavior: The mediation role of interactivity and e-WOM

Web 2.0 has changed the way consumers access information. This study aims to investigate the relationship between social media (Watsons’ Facebook page) content and consumers repurchase intention. In addition, it determined whether E-WOM and interactivity can act as the mediating variables between the social media content and repurchase decision. The data were collected through online and offline questionnaires. A total of 146 valid questionnaires were obtained and analyzed using Partial Least Square Structural Equation Modeling (PLS-SEM) through the SMART-PLS 3.3. 9 software. The findings support the direct effect of social media content on E-WOM, interactivity, and repurchase intention. Moreover, the results confirmed the mediating role of interactivity between social media content and repurchase intention, however, E-WOM does not mediate between social media content and repurchase intention. The present study suggests some managerial implications for beauty brand retailers and provides fundamental strategies related to their social media.
Analyzing Grammatical and Lexical Cohesion in A Legendary Short Story

Analyzing Grammatical and Lexical Cohesion in A Legendary Short Story Noprival Sekolah Tinggi Ilmu Kesehatan Harapan Ibu Jambi, Jambi, Indonesiae-mail: noprival@gmail.com (corresponding author) Alfian Universitas Islam Negeri Sulthan Thaha Saifuddin Jambi, Jambi, Indonesiae-mail: alfian@uinjambi.ac. id Robi SomaUniversitas Jambi, Jambi, Indonesiae-mail: robisoma858@unja.ac. id Abstract:Despite the existence of many studies on cohesion in discourse, little scholarly work reports grammatical and lexical cohesion in a short story. To fill this gap, the present study investigates these two aspects of cohesion in a legendary short story entitled “After Twenty Years. ” Halliday and Hasan’s (1976) theoretical framework of cohesion was used to guide the current study. We applied textual analysis as the appropriate approach to find out grammatical and lexical cohesion within the forms of text. The findings in the grammatical cohesions showed that reference had the highest frequency of the total cohesive devices. Also, under grammatical cohesion, conjunctions are found to exist. However, other aspects were not found within this short story, including substitution and ellipsis. On the other hand, repetition was dominantly used lexically among other aspects of lexical cohesion and sequentially followed by repetitions, hyponyms, synonyms, and antonyms. Only one aspect of lexical cohesion, the meronym, was not found. The overall results of the research indicated that the short story was a coherent discourse because both grammatical and lexical cohesion exist properly.
Pedagogy matters: A framework for critical community-engaged courses in higher education

This article describes specific pedagogical components of a community engagement project between students in a psychology course and youth at a juvenile justice centre (JJS). The purpose of the research was to illustrate how feminist and critical pedagogies can create reciprocal community engagement that provides a space for learning at both college and community sites. The researchers involved in this study included the professor of the Psychology of Women course, a senior college student who previously took the course, the JJS volunteer coordinator and an education professor. Together, they employed qualitative, single case study methodology in order to understand the complex social phenomena of this community-engaged course. The results demonstrate that lessons addressing social inequities are beneficial for youth in JJS and offer a way to alleviate the gap in gender-specific programming. They also create community and offer an empowerment lens. By explicitly focusing on the pedagogical choices of the partnership, this research contributes to an understanding of how critical community engagement can provide mutual benefits.
Nanocellulose-Based Adsorbents for Heavy Metal Ion

Heavy metal ions in industrial sewage constitute a serious threat to human health. Nanocellulose-based adsorbents are emerging as an environmentally friendly material platform for heavy metal ion removal based on their unique properties, which include high specific surface area, excellent mechanical properties, and biocompatibility. In this review, we cover the most recent works on nanocellulose-based adsorbents for heavy metal ion removal and present an in-depth discussion of the modification technologies for nanocellulose in the process of assembling high-performance heavy ion adsorbents. By introducing functional groups, such as amino, carboxyl, aldehyde, and thiol, the assembled nanocellulose-based adsorbents both remove single heavy metal ions and can selectively adsorb multiple heavy ions in water. Finally, the remaining challenges of nanocellulose-based adsorbents are pointed out. We anticipate that this review will provide indispensable guidance on the application of nanocellulose-based adsorbents for the removal of heavy metal ions.
Normal forms for linear mode conversion and Landau-Zener transitions in one dimension

Standard eikonal methods for the asymptotic analysis of coupled linear wave equations may fail when two eigenvalues of a matrix (the dispersion matrix) associated with the wave operator are both small in the same region of wave phase space. In this region the two eikonal modes associated with the two small eigenvalues are coupled, leading to a process called linear mode conversion or Landau-Zener coupling. A theory of linear mode conversion is presented in which geometric structure is emphasized. This theory is then used to identify the most generic type of mode conversion which occurs in one dimension. Finally, a general solution for this generic mode conversion problem is derived by transforming an arbitrary equation exhibiting generic mode conversion into an easily solvable normal form. This solution is given as a connection rule, with which one may continue standard eikonal wave solutions through mode conversion regions. 51 refs., 13 figs.