Miracle-dz/UniFAR-FTUs huggingface dataset:
Interspecific interactions between wild felids vary across scales and levels of urbanization

Abstract Ongoing global landscape change resulting from urbanization is increasingly linked to changes in species distributions and community interactions. However, relatively little is known about how urbanization influences competitive interactions among mammalian carnivores, particularly related to wild felids. We evaluated interspecific interactions between medium‐ and large‐sized carnivores across a gradient of urbanization and multiple scales. Specifically, we investigated spatial and temporal interactions of bobcats and pumas by evaluating circadian activity patterns, broad‐scale seasonal interactions, and fine‐scale daily interactions in wildland–urban interface (WUI), exurban residential development, and wildland habitats. Across levels of urbanization, interspecific interactions were evaluated using two‐species and single‐species occupancy models with data from motion‐activated cameras. As predicted, urbanization increased the opportunity for interspecific interactions between wild felids. Although pumas did not exclude bobcats from areas at broad spatial or temporal scales, bobcats responded behaviorally to the presence of pumas at finer scales, but patterns varied across levels of urbanization. In wildland habitat, bobcats avoided using areas for short temporal periods after a puma visited an area. In contrast, bobcats did not appear to avoid areas that pumas recently visited in landscapes influenced by urbanization (exurban development and WUI habitat). In addition, overlap in circadian activity patterns between bobcats and pumas increased in exurban development compared to wildland habitat. Across study areas, bobcats used sites less frequently as the number of puma photographs increased at a site. Overall, bobcats appear to shape their behavior at fine spatial and temporal scales to reduce encounters with pumas, but residential development can potentially alter these strategies and increase interaction opportunities. We explore three hypotheses to explain our results of how urbanization affected interspecific interactions that consider activity patterns, landscape configuration, and animal scent marking. Altered competitive interactions between animals in urbanized landscapes could potentially increase aggressive encounters and the frequency of disease transmission.
Vertex-based anisotropic texturing

MIP mapping is a common method used by graphics hardware to avoid texture aliasing. In many situations, MIP mapping over-blurs in one direction to prevent aliasing in another. Anisotropic texturing reduces this blurring by allowing differing degrees of filtering in different directions, but is not as common in hardware due to the implementation complexity of current techniques. We present a new algorithm that enables anisotropic texturing on any current MIP map graphics hardware supporting MIP level biasing, available in OpenGL 1.2 or through the GL_EXT_texture_lod_bias or GL_SGIX_texture_lod_bias OpenGL extensions. The new algorithm computes anisotropic filter footprint parameters per vertex. It constructs the anisotropic filter out of several MIP map texturing passes or multi-texture lookups. Each lookup uses MIP level bias and perturbed texture coordinates to place one probe used to construct the more complex filter profile.
Letter Visibility and the Optimal Viewing Position Effect of Isolated Connected and Un-Connected Letters in Arabic

Abstract The present study provides a further exploration of the role of Arabic letter visibility as a possible cause of the Optimal Viewing Position (OVP) effect. We used isolated connected and un-connected Arabic letters of different shapes (basic, initial, medial, final) placed at the center of fixation (Experiment 1) and at various possible positions in isolated presentation (Experiment 2). In order to investigate whether performance in the visual identification task is modulated by letter type, we presented each of the isolated connected and un-connected letter targets in each of the eleven stimulus positions across the array to produce a mean RT (ms) for each of the letter types. Using the initial fixation paradigm enabled us to compare reaction times with correctly identified letter targets appearing in the different possible positions. The findings of the present experiments demonstrated that visual letter recognition is influenced by: (i) the isolated letters’ type (connected, un-connected), as connected letters are easier to recognize than un-connected letters; (ii) isolated letters’ shape (basic, initial, medial, final), as medial and final are harder to recognize than basic and initial letter shapes; (iii) visual field, as reading rates were longer for letter stimuli that were presented in LVF compared to RVF; and (iv) eccentricity, as letter reading rates were correlated with their eccentric placement.
Identification of sarcomeric variants in probands with a clinical diagnosis of arrhythmogenic right ventricular cardiomyopathy (ARVC)

Arrhythmogenic right ventricular cardiomyopathy (ARVC) is an inherited cardiomyopathy characterized by ventricular arrhythmias and sudden death. Currently 60% of patients meeting Task Force Criteria (TFC) have an identifiable mutation in one of the desmosomal genes. As much overlap is described between other cardiomyopathies and ARVC, we examined the prevalence of rare, possibly pathogenic sarcomere variants in the ARVC population.
The Subgingival Microbiome of Periodontal Pockets With Different Probing Depths in Chronic and Aggressive Periodontitis: A Pilot Study

Periodontitis is a kind of infectious disease initiated by colonization of subgingival periodontal pathogens, which cause destruction of tooth-supporting tissues, and is a predominant threat to oral health as the most common cause of loss of teeth. The aim of this pilot study was to characterize the subgingival bacterial biodiversity of periodontal pockets with different probing depths in patients with different forms of periodontitis. Twenty-one subgingival plaque samples were collected from three patients with chronic periodontitis (ChP), three patients with aggressive periodontitis (AgP) and three periodontally healthy subjects (PH). Each patient with periodontitis was sampled at three sites, at different probing depths (PDs, one each at 4 mm, 5–6 mm, and ≥ 7 mm). Using 16S rRNA gene high-throughput sequencing and bioinformatic analysis, we found that subgingival communities in health and periodontitis samples largely differed. Meanwhile, Acholeplasma, Fretibacterium, Porphyromonas, Peptococcus, Treponema_2, Defluviitaleaceae_UCG_011, Filifactor, and Mycoplasma increased with the deepening of the pockets in ChP, whilst only Corynebacterium was negatively associated with PD. In AgP, Corynebacterium and Klebsiella were positively associated with PD, while Serratia, Pseudoramibacter, Defluviitaleaceae_UCG_011, and Desulfobulbus were negatively associated with PD. And among these two groups, Corynebacterium shifted differently. Moreover, in subgingival plaque, the unweighted UniFrac distances between samples from pockets with different PD in the same patients were significantly lower than those from pockets within the same PD category from different patients. This study demonstrated the shift of the subgingival microbiome in individual teeth sites during disease development. Within the limitation of the relative small sample size, this pilot study shed new light on the dynamic relationship between the extent of periodontal destruction and the subgingival microbiome.
Neuroleptiques Et Effets Extra-Pyramidaux: Correlation Entre Les Proprietes Antipsychotiques Et Extra-Pyramidales *

Data obtained in two comparative controlled studies of neuroleptics were used to ascertain if there were some correlation between the degree of improvement in the mental state and the severity of extrapyramidal symptoms induced in patients receiving one or other of the following neuroleptics: trifluperidol, trifluoperazine, T.P.S. -23 and chlorpromazine. In this study patients are used as experimental units. For each trial, the importance of psychiatric symptoms has been measured with the Brief Psychiatric Rating Scale and the neurological syndrome with the “Bilan extra-pyramidal” (Extrapyramidal Rating Scale). It has been impossible to find a correlation between the antipsychotic and extrapyramidal-inducing properties of the neuroleptics we have studied.
Effects of NAA and BAP, Double-Layered Media, and Light Distance on In Vitro Regeneration of Nelumbo nucifera Gaertn. (Lotus), an Aquatic Edible Plant

In vitro direct regeneration of Nelumbo nucifera Gaertn. was successfully achieved from immature explants (yellow plumule) cultured on a solid MS media supplemented with combinations of 0.5 mg/L BAP and 1.5 mg/L NAA which resulted in 16.00 ± 0.30 number of shoots per explant and exhibited a new characteristic of layered multiple shoots, while normal roots formed on the solid MS basal media. The double-layered media gave the highest number of shoots per explant with a ratio of 2 : 1 (liquid to solid) with a mean number of 16.67 ± 0.23 shoots per explant with the formation of primary and secondary roots from immature explants. In the study involving light distance, the tallest shoot (16.67 ± 0.23 mm) obtained from the immature explants was at a light distance of 200 mm from the source of inflorescent light (1000 lux). The plantlets were successfully acclimatized in clay loam soil after 8 months being maintained under in vitro conditions.
Multimodal concept-dependent active learning for image retrieval

It has been established that active learning is effective for learning complex, subjective query concepts for image retrieval. However, active learning has been applied in a concept independent way, (i.e., the kernel-parameters and the sampling strategy are identically chosen) for learning query concepts of differing <i>complexity</i>. In this work, we first characterize a concept's complexity using three measures: <i>hit-rate</i>, <i>isolation</i> and <i>diversity</i>. We then propose a multimodal learning approach that uses images' semantic labels to guide a <i>concept-dependent</i>, <i>active-learning</i> process. Based on the complexity of a concept, we make intelligent adjustments to the sampling strategy and the sampling pool from which images are to be selected and labeled, to improve concept learnability. Our empirical study on a $300$K-image dataset shows that concept-dependent learning is highly effective for image-retrieval accuracy.
Exploiting simultaneous observational constraints on mass and absorption to estimate the global direct radiative forcing of black carbon and brown carbon

Abstract. Atmospheric black carbon (BC) is a leading climate warming agent, yet uncertainties on the global direct radiative forcing (DRF) remain large. Here we expand a global model simulation (GEOS-Chem) of BC to include the absorption enhancement associated with BC coating and separately treat both the aging and physical properties of fossil-fuel and biomass-burning BC. In addition we develop a global simulation of brown carbon (BrC) from both secondary (aromatic) and primary (biomass burning and biofuel) sources. The global mean lifetime of BC in this simulation (4.4 days) is substantially lower compared to the AeroCom I model means (7.3 days), and as a result, this model captures both the mass concentrations measured in near-source airborne field campaigns (ARCTAS, EUCAARI) and surface sites within 30%, and in remote regions (HIPPO) within a factor of 2. We show that the new BC optical properties together with the inclusion of BrC reduces the model bias in absorption aerosol optical depth (AAOD) at multiple wavelengths by more than 50% at AERONET sites worldwide. However our improved model still underestimates AAOD by a factor of 1.4 to 2.8 regionally, with the largest underestimates in regions influenced by fire. Using the RRTMG model integrated with GEOS-Chem we estimate that the all-sky top-of-atmosphere DRF of BC is +0.13 Wm−2 (0.08 Wm−2 from anthropogenic sources and 0.05 Wm−2 from biomass burning). If we scale our model to match AERONET AAOD observations we estimate the DRF of BC is +0.21 Wm−2, with an additional +0.11 Wm−2 of warming from BrC. Uncertainties in size, optical properties, observations, and emissions suggest an overall uncertainty in BC DRF of −80%/+140%. Our estimates are at the lower end of the 0.2–1.0 Wm−2 range from previous studies, and substantially less than the +0.6 Wm−2 DRF estimated in the IPCC 5th Assessment Report. We suggest that the DRF of BC has previously been overestimated due to the overestimation of the BC lifetime (including the effect on the vertical profile) and the incorrect attribution of BrC absorption to BC.
Gain and phase dynamics of InAs/GaAs quantum dot semiconductor optical amplifiers

Ultrafast spectroscopy of quantum dot semiconductor optical amplifiers (SOAs) provides valuable information about the potential of these devices for emerging applications such as multi-wavelength regeneration while giving insight on their unique carrier dynamics. Pump-probe spectroscopy was used to analyse the carrier dynamics in InAs/GaAs quantum dot amplifiers. We have developed a ldquotwo-colourrdquo experimental configuration that allows us to pump and probe different parts of the amplified spontaneous emission spectrum and develop a detailed picture of the relevant carrier processes in both absorption and gain regimes of QD-SOAs. The study has revealed that hole recovery and intradot electron relaxation occur on a picosecond timescale, while the electron capture time is on the order of 10 ps. The relaxation of the wetting layer carrier density was shown to have a strong effect on the phase dynamics of both ground and excited state transients, while having a much weaker effect on the gain dynamics. Such behaviour is strongly encouraging for reduced pattern effect operation in high speed optical networks.
A scalable plane-based broadcast algorithm for 3D-Mesh networks

Broadcast algorithms for wormhole-switched meshes have been widely reported in the literature. However, most of these algorithms handle broadcast in a sequential manner and do not scale well with the network size. As a consequence, many parallel applications cannot be efficiently supported using existing algorithms. Motivated by these observations, this paper presents a new efficient broadcast algorithm for the mesh. The main feature of the proposed algorithm lies in its ability to perform broadcast operation with a high degree of scalability and parallelism. Furthermore, its performance is insensitive to the network size, i.e., only three message-passing steps are required to implement a broadcast operation irrespective of the network size. Results from a comparative analysis reveal that the new algorithm exhibits superior performance characteristics over those of the well-known Recursive Doubling, Extending Dominating Node.
Generation of TALEN-Mediated GRdim Knock-In Rats by Homologous Recombination

Transcription Activator-Like Effector Nucleases (TALEN) are potential tools for precise genome engineering of laboratory animals. We report the first targeted genomic integration in the rat using TALENs (Transcription Activator-Like Effector Nucleases) by homology-derived recombination (HDR). We assembled TALENs and designed a linear donor insert targeting a pA476T mutation in the rat Glucocorticoid Receptor (Nr3c1) namely GRdim, that prevents receptor homodimerization in the mouse. TALEN mRNA and linear double-stranded donor were microinjected into rat one-cell embryos. Overall, we observed targeted genomic modifications in 17% of the offspring, indicating high TALEN cutting efficiency in rat zygotes.
Robust H-infinity guaranteed cost Control for a class of nonlinear 2-D time delay discrete systems

In this paper ,the robust H∞ guaranteed cost control problem for nonlinear time delay discrete two dimensional (2-D) systems is investigated ,the nonlinear elements of systems satisfies Lipschitze condition,based on the stability theorem and linear matrix inequalities(LMI), firstly a sufficient condition of the controller existence is established , then the solvability of the robust controller designing problem is obtained by the LMI theory. The designed state feedback controller guarantes the closed loop system is stable and impuls free for time delays and disturbance,which has H∞ performance ,last a numerical example is provided to demonstrate the effectiveness of the proposed method.
Aspergillus nidulans CkiA is an essential casein kinase I required for delivery of amino acid transporters to the plasma membrane

Type I casein kinases are highly conserved among Eukaryotes. Of the two Aspergillus nidulans casein kinases I, CkiA is related to the δ/ε mammalian kinases and to Saccharomyces cerevisiæ Hrr25p. CkiA is essential. Three recessive ckiA mutations leading to single residue substitutions, and downregulation using a repressible promoter, result in partial loss‐of‐function, which leads to a pleiotropic defect in amino acid utilization and resistance to toxic amino acid analogues. These phenotypes correlate with miss‐routing of the YAT plasma membrane transporters AgtA (glutamate) and PrnB (proline) to the vacuole under conditions that, in the wild type, result in their delivery to the plasma membrane. Miss‐routing to the vacuole and subsequent transporter degradation results in a major deficiency in the uptake of the corresponding amino acids that underlies the inability of the mutant strains to catabolize them. Our findings may have important implications for understanding how CkiA, Hrr25p and other fungal orthologues regulate the directionality of transport at the ER‐Golgi interface.
An Adaptive System for Optimal Solar Energy Harvesting in Wireless Sensor Network Nodes

The success of wireless sensor networks and their pervasive use is somehow constrained by energy supply which, generally provided by batteries, is a finite resource. Energy harvesting mechanisms must hence be taken into account to grant a long time operational life, with solar energy being the most interesting one in outdoor deployments due to its relatively high power density. In this paper we propose a low-power maximum power point tracker (MPPT) circuit specifically designed for wireless sensor nodes (hence effective, flexible, low cost and power-aware), i.e., a power transferring circuit for optimally conveying solar energy into rechargeable batteries even in not optimal weather conditions. High efficiency is granted by an ad hoc adaptive algorithm which, by keeping the MPPT electronics in its optimal working point, maximizes energy transfer from the solar cell to the batteries. The suggested implementation is particularly effective in critical weather conditions where traditional solutions do not work and is characterized by a flexible enough design for immediately hosting, in a plug in fashion, different solar panels and battery typologies.
A Non-Canonical Function of Zebrafish Telomerase Reverse Transcriptase Is Required for Developmental Hematopoiesis

Although it is clear that telomerase expression is crucial for the maintenance of telomere homeostasis, there is increasing evidence that the TERT protein can have physiological roles that are independent of this central function. To further examine the role of telomerase during vertebrate development, the zebrafish telomerase reverse transcriptase (zTERT) was functionally characterized. Upon zTERT knockdown, zebrafish embryos show reduced telomerase activity and are viable, but develop pancytopenia resulting from aberrant hematopoiesis. The blood cell counts in TERT-depleted zebrafish embryos are markedly decreased and hematopoietic cell differentiation is impaired, whereas other somatic lineages remain morphologically unaffected. Although both primitive and definitive hematopoiesis is disrupted by zTERT knockdown, the telomere lengths are not significantly altered throughout early development. Induced p53 deficiency, as well as overexpression of the anti-apoptotic proteins Bcl-2 and E1B-19K, significantly relieves the decreased blood cells numbers caused by zTERT knockdown, but not the impaired blood cell differentiation. Surprisingly, only the reverse transcriptase motifs of zTERT are crucial, but the telomerase RNA-binding domain of zTERT is not required, for rescuing complete hematopoiesis. This is therefore the first demonstration of a non-canonical catalytic activity of TERT, which is different from “authentic” telomerase activity, is required for during vertebrate hematopoiesis. On the other hand, zTERT deficiency induced a defect in hematopoiesis through a potent and specific effect on the gene expression of key regulators in the absence of telomere dysfunction. These results suggest that TERT non-canonically functions in hematopoietic cell differentiation and survival in vertebrates, independently of its role in telomere homeostasis. The data also provide insights into a non-canonical pathway by which TERT functions to modulate specification of hematopoietic stem/progenitor cells during vertebrate development. (276 words)
SoleSound: Towards a novel portable system for audio-tactile underfoot feedback

This paper introduces the design of SoleSound, a wearable system designed to deliver ecological, audio-tactile, underfoot feedback. The device, which primarily targets clinical applications, uses an audio-tactile footstep synthesis engine informed by the readings of pressure and inertial sensors embedded in the footwear to integrate enhanced feedback modalities into the authors' previously developed instrumented footwear. The synthesis models currently implemented in the SoleSound simulate different ground surface interactions. Unlike similar devices, the system presented here is fully portable, and can therefore be utilized outside the laboratory setting. A first experimental evaluation indicates that the device can effectively modulate the perception of the ground surface during walking, thereby, inducing changes in the gait of healthy subjects.
Effects of season and experimental warming on the bacterial community in a temperate mountain forest soil assessed by 16S rRNA gene pyrosequencing

Climate warming may induce shifts in soil microbial communities possibly altering the long-term carbon mineralization potential of soils. We assessed the response of the bacterial community in a forest soil to experimental soil warming (+4 °C) in the context of seasonal fluctuations. Three experimental plots were sampled in the fourth year of warming in summer and winter and compared to control plots by 16S rRNA gene pyrosequencing. We sequenced 17 308 amplicons per sample and analysed operational taxonomic units at genetic distances of 0.03, 0.10 and 0.25, with respective Good's coverages of 0.900, 0.977 and 0.998. Diversity indices did not differ between summer, winter, control or warmed samples. Summer and winter samples differed in community structure at a genetic distance of 0.25, corresponding approximately to phylum level. This was mainly because of an increase of Actinobacteria in winter. Abundance patterns of dominant taxa (> 0.06% of all reads) were analysed individually and revealed, that seasonal shifts were coherent among related phylogenetic groups. Seasonal community dynamics were subtle compared to the dynamics of soil respiration. Despite a pronounced respiration response to soil warming, we did not detect warming effects on community structure or composition. Fine-scale shifts may have been concealed by the considerable spatial variation.