Miracle-dz/UniFAR-FTUs huggingface dataset:
Histochemical demonstration of acid phosphatase activity in various blood cells.

Acid phosphatase activity of various blood cells were histochemically observed on peripheral blood and bone marrow smears using the azo dye method which had been reported in my previous paper, and following results were obtained. 1) In the neutrophilic granulocyte series, the largest acid phosphatase score was obtained in immature cells, which might include promyelocytes, myelocytes, and metamyelocytes. Mature neutrophils were stained moderately, and blast cells showed weak staining. 2) Eosinophils showed strong activity, and basophils seemed to have weak activity. 3) Monocytes disclosed strong activity, and lymphocytes slight activity. 4) Erythroblasts had slight activity, and it seemed that they lost gradually the enzyme activity with the advance of cell maturation. 5) In plasma cells, reticulum cells and megakaryocytes, strong activity of the enzyme was demonstrated. 6) Mast cells showed moderately strong activity on the bone marrow smears from a case of urticaria pigmentosa. In spite of a considerable literature dealing with the distribution of alkaline phosphatase in hematopoietic cells,1 little work has been done in regard to acid phosphatase. Moreover, there are differences in opinion as to the activity of acid phosphatase in certain blood cells.2-7 In previous reports dealing with the demonstration of acid phosphatase in hematopoietic cells, most of the observations were carried out by the Gomori's metal salt method or its modifications, which often brought about nonspecific pseudoreaction such as nuclear staining. In recent years azo dye method has been introduced into the histochemical study of blood cells. In my previous papers it was shown that Pearse's azo dye method for tissue section10 could be applied with some modifications to the demonstration of acid phosphatase activity of blood cells in peripheral blood and bone marrow smears. This paper deals with the results of the histochemical observations with this method of acid phosphatase activity of various blood cells.
VKCDB: voltage-gated K+ channel database updated and upgraded

The Voltage-gated K+ Channel DataBase (VKCDB) (http://vkcdb.biology.ualberta.ca) makes a comprehensive set of sequence data readily available for phylogenetic and comparative analysis. The current update contains 2063 entries for full-length or nearly full-length unique channel sequences from Bacteria (477), Archaea (18) and Eukaryotes (1568), an increase from 346 solely eukaryotic entries in the original release. In addition to protein sequences for channels, corresponding nucleotide sequences of the open reading frames corresponding to the amino acid sequences are now available and can be extracted in parallel with sets of protein sequences. Channels are categorized into subfamilies by phylogenetic analysis and by using hidden Markov model analyses. Although the raw database contains a number of fragmentary, duplicated, obsolete and non-channel sequences that were collected in early steps of data collection, the web interface will only return entries that have been validated as likely K+ channels. The retrieval function of the web interface allows retrieval of entries that contain a substantial fraction of the core structural elements of VKCs, fragmentary entries, or both. The full database can be downloaded as either a MySQL dump or as an XML dump from the web site. We have now implemented automated updates at quarterly intervals.
Blood Pressure Management in Acute Intracerebral Hemorrhage: Relationship Between Elevated Blood Pressure and Hematoma Enlargement

Background and Purpose— The association between elevated blood pressure (BP) and hematoma enlargement in acute intracerebral hemorrhage (ICH) has not been clarified. We investigated the association between maximum systolic BP (SBP) and hematoma enlargement, measuring SBP between a baseline and a second CT scan in patients with hypertensive ICH. Methods— We assessed 76 consecutive patients with hypertensive ICH retrospectively. We usually attempted to lower SBP below targets of 140, 150, or 160 mm Hg. Recordings of serial BP from admission until the second CT scan were assessed. A neuroradiologist, who was not informed of the aim of this study, reviewed CT films. Hematoma enlargement was defined as an increase in volume of ≥140% or 12.5 cm3. Results— Hematoma enlargement occurred in 16 patients. Maximum SBP was significantly associated with hematoma enlargement (P = 0.0074). A logistic regression model for predicting hematoma enlargement was constructed with the use of maximum SBP, hematoma volume, and Glasgow Coma Scale score at admission. After adjustment for these factors, maximum SBP was independently associated with hematoma enlargement (odds ratio per mm Hg, 1.04; 95% CI, 1.01 to 1.07). Target SBPs of ≥160 mm Hg were significantly associated with hematoma enlargement compared with those of ≤150 mm Hg (P = 0.025). Conclusions— Our findings suggest that elevated BP increases the risk of hematoma enlargement. Efforts to lower SBP below 150 mm Hg may prevent this risk.
WWW performance over GPRS

We present investigative results of HTTP performance over GPRS (General Packet Radio Service). Following on from an earlier study of GPRS, in which we uncovered a number of performance problems with TCP (e.g. sub-optimal start-up performance, excess queueing, spurious timeouts etc.), we discuss how and to what extent these limitations can impact HTTP. We also examine some other issues specifically linked to HTTP performance over GPRS. Our experimental results show that aggressive behaviour on the part of Web browsers optimized for the wired-Internet does not work well over GPRS. Instead, limiting the number of browser TCP connections, which enables aggressive pipelining of requests, can give significant performance benefits. We show that using a proxy located close to the wired-wireless boundary that implements performance enhancements at both the transport (TCP) and application layer can lead to substantial reduction in Web page download times over GPRS.
Relationship of Physical Performance with Body Composition and Bone Mineral Density in Individuals over 60 Years of Age: A Systematic Review

The purpose of this review was to examine the relationship between physical performance and body composition measurements, including fat/muscle mass and bone mineral density (BMD) in individuals ≥60 years of age. Various measurements used to assess body composition, BMD, and physical performance (PP) were discussed as well. Medline/PubMed, CINAHL, and SCIE were used to identify articles. After limiting the search for age and kind of physical performance measures, 33 articles were evaluated. Higher fat mass was associated with poorer physical performance while higher muscle mass was a predictor of better physical performance, especially in the lower extremities. Additionally, evidence showed that higher muscle fat infiltration was a determinant of poorer physical performance. BMD was shown to be a good predictor of physical performance although the relationship was stronger in women than in men. Developing standardized methods for PP measurements could help in further investigation and conclusions of its relationship with body composition.
Design of Resource Efficient Low Power Correlator for Communication

This paper deals with the timing synchronization re source utilization and power consumption problems of OFDM . Nowadays multiplier based correlators are used in OFDM systems. It occupies large a reas making it tough to fit in VLSI devices. Hence in th is project we proposed a new technique which uses multiplierless correlators in OFDM systems . Multipl ierless correlators based on multiple constant mult iplication technique for area reduction is used in modified co rrelator. These correlators can fit on low power VL SI devices thus resource utilization can be done effectively. Comparison of multiplier based correlator and multi ple constant multiplications by using carry look ahead adder and carry select adder correlator gives the c lear understanding of area overhead problem. Thus multiplierless correlators provide accurate timing synchronization even at high clock speeds. Thus sim ulated output generator using MODELSIM and Xilinx shows that the OFDM using multiplierless correlator s gives better timing synchronization than OFDM using multiplier based correlators.
Value-Mapped Peer Data Sharing Systems and Consistent Query Answering

A peer data sharing system consists of peers where a database in a peer is designed and administered autonomously. Acquaintances between peers are used to share data among peers. These acquaintances are established thorough data sharing constraints. Data between peers may be inconsistent with respect to constraints due to the change of constraints (e.g. adding, modifying, and deleting constraints between peers) and data updates in individual peer. One possible solution to resolve inconsistencies is to modify data physically in inconsistent peers through update propagation. This strategy is not practical since peers are autonomous and a peer may not have permission to modify other peers’ data. Considering the possible inconsistent situations, this paper discusses a semantics and a technique for obtaining consistent answers. Consistent answers are obtained at query time by avoiding the inconsistent data.
Mirror Therapy Promotes Recovery From Severe Hemiparesis: A Randomized Controlled Trial

Background. Rehabilitation of the severely affected paretic arm after stroke represents a major challenge, especially in the presence of sensory impairment. Objective. To evaluate the effect of a therapy that includes use of a mirror to simulate the affected upper extremity with the unaffected upper extremity early after stroke. Methods. Thirty-six patients with severe hemiparesis because of a first-ever ischemic stroke in the territory of the middle cerebral artery were enrolled, no more than 8 weeks after the stroke. They completed a protocol of 6 weeks of additional therapy (30 minutes a day, 5 days a week), with random assignment to either mirror therapy (MT) or an equivalent control therapy (CT). The main outcome measures were the Fugl-Meyer subscores for the upper extremity, evaluated by independent raters through videotape. Patients also underwent functional and neuropsychological testing. Results. In the subgroup of 25 patients with distal plegia at the beginning of the therapy, MT patients regained more distal function than CT patients. Furthermore, across all patients, MT improved recovery of surface sensibility. Neither of these effects depended on the side of the lesioned hemisphere. MT stimulated recovery from hemineglect. Conclusions. MT early after stroke is a promising method to improve sensory and attentional deficits and to support motor recovery in a distal plegic limb.
A Comparative Review: Accurate OpenFlow Simulation Tools for Prototyping

Several Simulation and emulation tools such as the OMNeT++ INET Framework and Mininet have been developed to evaluate the performance of Software-Defined Networking (SDN). A major challenge is how to analyse the obtained performance results of data transmission for these tools. These challenges include scaling to large networks, testing the correctness and evaluating the performance with the ability to easily migrate to a real system with minimal changes for deployment. Current methods for testing the functions and evaluating the performances of SDN include new programming languages, static analysis and debugging capability, and innovative frameworks of simulation tools. In this paper, we describe the implementation model of OpenFlow system in the INET framework for OMNeT++. The simulation approaches were designed for prototyping and evaluating new SDN-based applications accurately at low cost, while being flexible, scalable, controllable, and accessible to many users. We describe the design and the use of the simulation modules, and demonstrate its capability by carrying out a series of experiments. In addition, we compare the OpenFlow functions of OMNeT++ simulator with the popular Mininet emulator in identical traffic configurations. The measurement results derived from both tools show that they are correct, accurate, and repeatable regarding their capabilities, performance, and functionalities
Timbre Features and Music Emotion in Plucked String, Mallet Percussion, and Keyboard Tones

Music conveys emotions by means of pitch, rhythm, loudness, and many other musical qualities. It was recently confirmed that timbre also has direct association with emotion, for example, that a horn is perceived as sad and a trumpet heroic in even isolated instrument tones. As previous work has mainly focused on sustaining instruments such as bowed strings and winds, this paper presents an experiment with non-sustaining instruments, using a similar approach with pairwise comparisons of tones for emotion categories. Plucked string, mallet percussion, and keyboard instrument tones were investigated for eight emotions: Happy, Sad, Heroic, Scary, Comic, Shy, Joyful, and Depressed. We found that plucked string tones tended to be Sad and Depressed, while harpsichord and mallet percussion tones induced positive emotions such as Happy and Heroic. The piano was emotionally neutral. Beyond spectral centroid and its deviation, which are important features in sustaining tones, decay slope was also significantly correlated with emotion in non-sustaining tones.
Labeling network motifs in protein interactomes for protein function prediction

Biological networks such as the protein-protein interaction (PPI) network have been found to contain small recurring subnetworks in significantly higher frequencies than in random networks. Such network motifs are useful for uncovering structural design principles of complex biological networks. However, current network motif finding algorithms models the PPI network as a uni-labeled graph, discovering only unlabeled and thus relatively uninforma-tive network motifs as a result. Our objective is to exploit the currently available biological information that are associated with the vertices (the proteins) to capture not only the topological shapes of the motifs, but also the biological context in which they occurred in the PPI networks for network motif applications. We present a method called LaMoFinder to label network motifs with gene ontology terms in a PPI network. We also show how the resulting labeled network motifs can be used to predict unknown protein functions. Experimental results showed that the labeled network motifs extracted are biologically meaningful and can achieve better performance than existing PPI topology based methods for predicting unknown protein functions.
Profiling is Politically 'Correct': Agent-Based Modeling of Ethno-Political Conflict

A holy grail for military, diplomatic, and intelligence analysis is a valid set of software agent models that act as the desired ethno-political factions so that one can test the effects that may arise from alternative courses of action in different lands. This article enumerates the challenges of such a testbed and describes best-of-breed leader and follower profiling models implemented to improve the realism and validity of the agent. Realistic, ‘descriptive’ agents are contrasted to rational actor theory in terms of the different equilibria one would expect to emerge in conflict games. These predictions are examined in two real world cases (Iraq and SE Asia) where the agent models are subjected to validity tests and a policy experiment is then run. We conclude by arguing that substantial effort on game realism, best-of-breed social science models, and agent validation efforts is essential if analytic experiments are to effectively explore conflicts and alternative ways to influence outcomes. Such efforts are likely to improve behavioral game theory as well.
Fuss , Futexes and Furwocks : Fast Userlevel Locking in Linux Hubertus Franke IBM

Fast userlevel locking is an alternative locking mechanism to the typically heavy weight kernel approaches such as fcntl locking and System V semaphores. Here, multiple processes communicate locking state through shared memory regions and atomic operations. Kernel involvement is only necessary when there is contention on a lock, in order to perform queueing and scheduling functions. In this paper we discuss the issues related to user level locking by following the history of ideas and the code to the current day. We present the efficacy of "futexes" through benchmarks, both synthetic and through adaptations to existing databases. We conclude by presenting the potential future directions of the "futex" interface.
User acceptance of pervasive computing in healthcare: Main findings of two case studies

The successful implementation of pervasive computing technologies in healthcare does not only depend on technical issues but also on acceptability and acceptance issues. In this paper we focus on factors that facilitate or inhibit user acceptance of pervasive computing in healthcare. We present selected findings of the research project dasiaPerCoMed - Pervasive Computing in Healthcarepsila. The project is based on two case studies in pre- and post-clinical healthcare. In the first study, the potential of pervasive computing technologies for the treatment of acute cardiovascular diseases is investigated, in the second case study, the potential for the treatment of multiple sclerosis (MS) is evaluated. A qualitative user acceptance analysis of the two case studies shows the following results: the main factor of user acceptance is the perceived medical usefulness. Furthermore, acceptance is strongly inhibited if data privacy or if subjective norms are violated. Usability only presents a decisive factor of acceptance if problems with usability reduce the perceived usefulness.
DETECTING GROUND SETTLEMENT OF SHANGHAI USING INTERFEROMETRIC SYNTHETIC APERTURE RADAR ( INSAR ) TECHNIQUES

Differential (D) and persistent scatterer (PS) interferometric synthetic aperture radar (InSAR) (DInSAR and PSInSAR) techniques are arguably the most cost effective and efficient methods today for ground surface deformation monitoring since their invention in the last quarter of the twentieth century. They overcome the limitations of traditional methods of deformation monitoring with regards to cost, time, man power and environmental conditions. A study has been conducted using the above techniques to investigate the land subsidence phenomena in Shanghai. Data from both the European Remote Sensing (ERS) Satellite 1 and 2 (ERS-1/2) and the Japanese Earth Resource Satellite 1 (JERS-1) were used. Results of ground surface subsidence using (i) the DInSAR technique with the L-band JERS-1 SAR data, and (ii) the PSInSAR technique with the C-band ERS-1/2, have been produced for Shanghai. Consistent deformation rates for each dataset used have been produced using the DInSAR and the PSInSAR techniques. Qualitative analysis of the differential interferograms produced from L-band JERS-1 SAR data yields a more accurate and consistent land subsidence pattern in Shanghai. Three stages of land subsidence are revealed by a series of L-band JERS-1 differential interferograms covering Shanghai from 1992-1998. The results obtained from PSInSAR processing, although a bit noisy, are also in agreement with both the results obtained from the DInSAR processing, and land subsidence map of Shanghai produced from other survey techniques. * Corresponding author
Visão dos clientes externos sobre a satisfação dos serviços de enfermagem hospitalar: abordagem interpessoal

Resumo: O estudo objetivou descrever a qualidade da assistencia de enfermagem hospitalar e a satisfacao do cliente externo por meio de uma abordagem interpessoal, durante o periodo de internacao em um hospital polo referencia para a regiao ampliada de saude. Trata-se de um estudo descritivo, realizado com 223 clientes externos. Para a coleta de dados aplicou-se o Instrumento de Satisfacao do Paciente (ISP), adaptado e validado no Brasil, enfocando o dominio confianca. Os dados foram digitados no programa SPSS, versao 20. Procedeu-se analise descritiva das variaveis. Houve predominio do sexo masculino, casados e ensino medio incompleto. A media de satisfacao dos pacientes com o atendimento de enfermagem encontrada para o dominio confianca foi de 3,78, indicando boa satisfacao do cliente. 80,7% acham que o enfermeiro e atencioso e 75,8% paciente, porem 81,6% nao o consideram uma pessoa agradavel; 78,5% nao se sentem a vontade para fazer perguntas. Nesse sentido, reforca-se a importância do papel do enfermeiro e da pratica humanizada no processo do cuidado possibilitando assim a melhoria continua na qualidade da assistencia prestada.
How to measure episodic memory in 12-month-old infants : Implications for future research

We aim to introduce some new solutions in the studies involving the subjects who are not able to use spoken language, both animals and pre-verbal infants. Although our research focuses in general on the episodic memory introduced by Tulving in 1972, this paper is to present the case of 12-month-old infants.
A highly acid-resistant novel strain of Lactobacillus johnsonii No. 1088 has antibacterial activity, including that against Helicobacter pylori, and inhibits gastrin-mediated acid production in mice

A novel strain of Lactobacillus johnsonii No. 1088 was isolated from the gastric juice of a healthy Japanese male volunteer, and characterized for its effectiveness in the stomach environment. Lactobacillus johnsonii No. 1088 was found to have the strongest acid resistance among several lactobacilli examined (>10% of cells survived at pH 1.0 after 2 h), and such a high acid resistance property was a specific characteristic of this strain of L. johnsonii. When cultured with various virulent bacteria, L. johnsonii No. 1088 inhibited the growth of Helicobacter pylori, Escherichia coli O‐157, Salmonella Typhimurium, and Clostridium difficile, in which case its effectiveness was more potent than that of a type strain of L. johnsonii, JCM2012. In addition to its effect in vitro, L. johnsonii No. 1088 inhibited the growth of H. pylori in human intestinal microbiota‐associated mice in both its live and lyophilized forms. Moreover, L. johnsonii No. 1088 suppressed gastric acid secretion in mice via decreasing the number of gastrin‐positive cells in the stomach. These results taken together suggest that L. johnsonii No. 1088 is a unique lactobacillus having properties beneficial for supporting H. pylori eradication by triple therapy including the use of a proton pump inhibitor (PPI) and also for prophylaxis of gastroesophageal reflux disease possibly caused after H. pylori eradication as a side effect of PPI.
Computational Intelligence and Machine Learning Methods in Bioinformatics

aDSI, Dipartimento di Scienze dell’ Informazione, Universita degli Studi di Milano, Via Comelico 39, Milan, Italy. bDMI, Dipartimento di Matematica e Informatica, Universita di Salerno, Via Ponte don Melillo, Fisciano (SA), Italy. cDISI, Dipartimento di Informatica e Scienze dell’ Informazione, Universita di Genova, Via Dodecaneso 35, Genoa, Italy. d Center for Biotechnology, Temple University, 1900 N 12th Street Philadelphia, PA 19122, USA.