Miracle-dz/UniFAR-FTUs huggingface dataset:
Effective Anomaly Detection with Scarce Training Data

Learning-based anomaly detection has proven to be an effective black-box technique for detecting unknown attacks. However, the effectiveness of this technique crucially depends upon both the quality and the completeness of the training data. Unfortunately, in most cases, the traffic to the system (e.g., a web application or daemon process) protected by an anomaly detector is not uniformly distributed. Therefore, some components (e.g., authentication, payments, or content publishing) might not be exercised enough to train an anomaly detection system in a reasonable time frame. This is of particular importance in real-world settings, where anomaly detection systems are deployed with little or no manual configuration, and they are expected to automatically learn the normal behavior of a system to detect or block attacks. In this work, we first demonstrate that the features utilized to train a learning-based detector can be semantically grouped, and that features of the same group tend to induce similar models. Therefore, we propose addressing local training data deficiencies by exploiting clustering techniques to construct a knowledge base of well-trained models that can be utilized in case of undertraining. Our approach, which is independent of the particular type of anomaly detector employed, is validated using the realistic case of a learning-based system protecting a pool of web servers running several web applications such as blogs, forums, or Web services. We run our experiments on a real-world data set containing over 58 million HTTP requests to more than 36,000 distinct web application components. The results show that by using the proposed solution, it is possible to achieve effective attack detection even with scarce training data.
NanoQplus : A Multi-Threaded Operating System with Memory Protection Mechanism for WSNs

Sensor networks are specially constructed networks for collecting data from sensor nodes and delivering it to sink nodes at the end. Each nodes in a sensor network are small embedded systems, which require wireless communication among them with limited hardware constraints. If programmers develop sensor network applications for a large-area sensor network, the development of application will be very difficult without any support of operating system. Therefore, we developed a small operating system, referred to as NanoQplus, to enable to build a large-scale sensor network application rapidly and efficiently. NanoQplus is a multi-threaded, lightweight and low-power sensor network operating system. Although multi-threaded operating systems in sensor nodes need to manage multiple stacks to prevent the stack overflow problem, NanoQplus gives an elegant solution with a memory protection mechanism. This paper describes all about NanoQplus technologies; a philosophy, design issues, architecture, supported software products and NanoQplus programming style. Index Terms – Wireless Sensor Networks, Small Embedded Operating System, NanoQplus
Program abstractions for behaviour validation

Code artefacts that have non-trivial requirements with respect to the ordering in which their methods or procedures ought to be called are common and appear, for instance, in the form of API implementations and objects. This work addresses the problem of validating if API implementations provide their intended behaviour when descriptions of this behaviour are informal, partial or non-existent. The proposed approach addresses this problem by generating abstract behaviour models which resemble typestates. These models are statically computed and encode all admissible sequences of method calls. The level of abstraction at which such models are constructed has shown to be useful for validating code artefacts and identifying findings which led to the discovery of bugs, adjustment of the requirements expected by the engineer to the requirements implicit in the code, and the improvement of available documentation.
Durability of improvement in post-traumatic stress disorder symptoms and absence of harmful effects or drug dependency after 3,4-methylenedioxymethamphetamine-assisted psychotherapy: a prospective long-term follow-up study

We report follow-up data evaluating the long-term outcomes for the first completed trial of 3,4-methylenedioxymethamphetamine (MDMA)-assisted psychotherapy for chronic, treatment-resistant post-traumatic stress disorder (PTSD) (Mithoefer et al., 2011). All of the 19 subjects who received MDMA-assisted treatment in the original trial participated in the long-term follow-up (LTFU), with 16 out of 19 completing all of the long-term outcome measures, which were administered from 17 to 74 months after the original study’s final MDMA session (mean = 45.4; SD = 17.3). Our primary outcome measure used was the Clinician-Administered PTSD Scale (CAPS). Secondary outcome measures were the Impact of Events Scale-Revised (IES-R) and the Neuroticism Extroversion Oppenness Personality Inventory-Revised (NEO PI-R) Personality Inventory. We also collected a long-term follow-up questionnaire. Results for the 16 CAPS completers showed there were no statistical differences between mean CAPS score at LTFU (mean = 23.7; SD = 22.8) (t matched = 0.1; df = 15, p = 0.91) and the mean CAPS score previously obtained at Study Exit (mean = 24.6, SD = 18.6). On average, subjects maintained statistically and clinically-significant gains in symptom relief, although two of these subjects did relapse. It was promising that we found the majority of these subjects with previously severe PTSD who were unresponsive to existing treatments had symptomatic relief provided by MDMA-assisted psychotherapy that persisted over time, with no subjects reporting harm from participation in the study.
Comparison of the Degree of Exercise Tolerance in Children After Surgical Treatment of Complex Cardiac Defects, Assessed Using Ergospirometry and the Level of Brain Natriuretic Peptide

AbstractChildren who underwent surgery for complex congenital heart defects present worse exercise capacity than their healthy peers. In adults and adolescents, heart failure is assessed on the basis of clinical symptoms using the New York Heart Association (NYHA) score, while in an infant Ross scale; heart failure can also be evaluated by other parameters. The purpose of this study was to compare the degree of exercise tolerance in children after surgery for complex heart defects, assessed by the ratio of maximum oxygen uptake (VO2max) and the brain natriuretic peptide (N-terminal fragment of the prohormone brain-type natriuretic peptide [NT-proBNP]) concentration.The study group consisted of 42 children, ages 9 to 17 years (mean 14.00 ± 2.72). Among them there were 22 children with tetralogy of Fallot (ToF) after total correction, 18 children with transposition of the great arteries (d-TGA) after the arterial switch operation, and 2 children with single ventricle (SV) after the Fontan operation. All but 1 child were in NYHA class I. The control group consisted of 20 healthy children. Outcomes of interest were the ratio of VO2max, determined during ergospirometry, and the level of NT-proBNP. The statistical analysis was performed and the groups were considered significantly different for P < 0.05. There was no statistically significant correlation between NT-proBNP and maximum oxygen uptake (VO2) kg−1 min−1 in the study group compared with the control group.The VO2max in the test group had a mean value less (34.6 ± 8.0) than controls (38.4 ± 7.7), and the differences were statistically significant (P = 0.041). In contrast, the average concentration of NT-proBNP in the study group was higher than controls (117.9 ± 74.3 vs 18.0 ± 24.5), and these differences were statistically significant (P < 0.001). After operations for complex heart defects (ToF, TGA, and SV), children have worse heart function parameters and exercise capacity than the healthy population. To control this, we recommend postoperative ergospirometry and determination of NT-proBNP concentrations.
Mixing Rates of Random Walks with Little Backtracking

Many regular graphs admit a natural partition of their edge set into cliques of the same order such that each vertex is contained in the same number of cliques. In this paper, we study the mixing rate of certain random walks on such graphs and we generalize previous results of Alon, Benjamini, Lubetzky and Sodin regarding the mixing rates of non-backtracking random walks on regular graphs.
In vitro antibacterial activity of Camellia sinensis extract against cariogenic microorganisms

Context: Dental caries, a ubiquitous multifactorial infectious disease, is primarily caused by microorganisms like Streptococcus mutans and Lactobacillus acidophilus. Use of antimicrobials is an important strategy to curb cariogenic microorganisms. Aim: The aim was to evaluate the in vitro antimicrobial activity of C. sinensis extract on S. mutans and L. acidophilus. Study Setting and Design: Experimental design, in vitro study, lab setting. Materials and Methods: Aqueous, acetone and ethanolic extracts of C. sinensis were subjected to antioxidant analysis. The ethanolic extract was used for assessment of antimicrobial properties. Ethanolic green tea extract at ten different concentrations and 0.2% chlorhexidine was used. Microbiological investigations were carried out to determine the minimum inhibitory concentration (MIC), minimum bactericidal concentration (MBC) and zone of Inhibition of the test and control agents against S. mutans and L. acidophilus. Statistical Analysis: Kruskall-Wallis and Mann-Whitney U-test. Results: MIC of green tea extract on S. mutans and L. acidophilus was found to be 0.2% and 0.3% respectively, MBC was found to be 0.8% and 0.9%, respectively. The mean zone of inhibition for 30 μl containing 300 μg of ethanolic extract of green tea and control against S. mutans were 18.33 mm and 14.67 mm, respectively. The mean zone of inhibition for 30 μl containing 300 μg of ethanolic extract of green tea and control against L. acidophilus were 12.67 mm and 7.33 mm, respectively. Conclusion: Green tea has antibacterial activity against predominant cariogenic bacteria namely S. mutans and L. acidophilus.
FriendGlass : A privacy preserving ambient location display

Ambient displays are becoming popular forms of providing users with information in the periphery. Users are often interested in locations and activities that take place in a building. As a result, it is appropriate to create ambient displays to share the locations of users in a building. However, location systems are highly privacy-sensitive, so it is important to consider the privacy ramifications of such an ambient display. In this paper, we present an ambient location display called FriendGlass, which was designed with privacy support as a main feature. In this paper, we present the design process for FriendGlass, which included a small user survey which aided the designers in determining the needs of users for such a system. Finally, we present a discussion concerning the barriers to performing user tests for privacy sensitive ubiquitous systems such as FriendGlass.
A gestão do cuidado sob a ótica de enfermeiros supervisores

Objetivo: descrever as percepcoes de enfermeiros supervisores sobre as praticas de gestao do cuidado, e, construir coletivamente um conceito. Metodos: descritivo-exploratoria, de natureza qualitativa, realizada com 15 enfermeiros supervisores, empregando-se o Circulo de Cultura freireano como tecnica de coleta de dados. Os encontros foram gravados, transcritos e analisados segundo suas estruturas tematicas. Resultados: atraves da concepcao individual, considerou-se a gestao do cuidado como responsabilidade complexa, com foco em acoes burocraticas. A concepcao coletiva, relaciona a gestao com a sistematizacao da assistencia que resulta no cuidado integral e de qualidade. Quanto as dificuldades na gestao do cuidado destacaram-se aspectos relacionados a instituicao como, a falta de padronizacao de normas e rotinas, estrutura fisica e os recursos humanos. Conclusao: o principal desafio estabelecido e a superacao da percepcao fragmentada entre gestao e cuidado. Vislumbra-se na educacao permanente estrategia de intervencao a fim de qualificar a equipe para a gestao do cuidado.
The Ages of Very Cool Hydrogen-rich White Dwarfs

The evolution of white dwarfs is essentially a cooling process that depends primarily on the energy stored in their degenerate cores and on the transparency of their envelopes. In this paper we compute accurate cooling sequences for carbon-oxygen white dwarfs with hydrogen dominated atmospheres for the full range of masses of interest. For this purpose we use the most accurate available physical inputs for both the equation of state and opacities of the envelope and for the thermodynamic quantities of the degenerate core. We also investigate the role of the latent heat in the computed cooling sequences. We present separately cooling sequences in which the effects of phase separation of the carbon-oxygen binary mixture upon crystallization have been neglected, and the delay introduced in the cooling times when this mechanism is properly taken into account, in order to compare our results with other published cooling sequences which do not include a treatment of this phenomenon. We find that the cooling ages of very cool white dwarfs with pure hydrogen atmospheres have been systematically underestimated by roughly 1.5 Gyr at log(L/L☉) = -4.5 for an otherwise typical ~0.6 M☉ white dwarf, when phase separation is neglected. If phase separation of the binary mixture is included, then the cooling ages are further increased by roughly 10%. Cooling tracks and cooling isochrones in several color-magnitude diagrams are presented as well.
Quantum algorithm for approximating partition functions

We achieve a quantum speed-up of fully polynomial randomized approximation schemes (FPRAS) for estimating partition functions that combine simulated annealing with the Monte-Carlo Markov Chain method and use non-adaptive cooling schedules. The improvement in time complexity is twofold: a quadratic reduction with respect to the spectral gap of the underlying Markov chains and a quadratic reduction with respect to the parameter characterizing the desired accuracy of the estimate output by the FPRAS. Both reductions are intimately related and cannot be achieved separately. First, we use Grover’s fixed point search, quantum walks and phase estimation to efficiently prepare approximate coherent encodings of stationary distributions of the Markov chains. The speed-up we obtain in this way is due to the quadratic relation between the spectral and phase gaps of classical and quantum walks. Second, we generalize the method of quantum counting, showing how to estimate expected values of quantum observables. Using this method instead of classical sampling, we obtain the speed-up with respect to accuracy.
Current Loss-of-Function Mutations in the Thyrotropin Receptor Gene: When to Investigate, Clinical Effects, and Treatment

Thyroid-stimulating hormone receptor (TSHR) loss-of-function (LOF) mutations lead to a wide spectrum of phenotypes, ranging from severe congenital hypothyroidism (CH) to mild euthyroid hyperthyrotropinemia. The degree of TSH resistance depends on the severity of the impairment of the receptor function caused by the mutation and on the number of mutated alleles In this review data about genotype-phenotype correlation and criteria for clinical work-up will be presented and discussed. Complete TSH resistance due to biallelic LOF TSHR mutations must be suspected in all patients with severe not syndromic CH and severe thyroid hypoplasia diagnosed at birth by neonatal screening. Partial forms of TSH resistance show a more heterogeneous hormonal and clinical pattern . In these cases TSH serum levels are above the upper limit of normal range for the age but with a very variable pattern, free thyroxine (T4) concentrations are within the normal range and thyroid size can be normal or hypoplastic at ultrasound scan. An early substitutive treatment with L-T4 must be mandatory in all patients with severe CH due to complete uncompensated TSH resistance diagnosed at birth by neonatal screening. The usefulness of substitutive treatment appears much more controversial in patients with subclinical hypothyroidism due to partial TSH resistance in whom the increased TSH concentration should be able to compensate the mild functional impairment of the mutant receptor. Together with standard criteria we recommend also an accurate clinical work-up to select patients who are candidates for a LOF TSHR mutation. Conflict of interest:None declared.
International Journal of Women's Health Dovepress Postcesarean Wound Infection: Prevalence, Impact, Prevention, and Management Challenges

hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. For permission for commercial use of this work, please see paragraphs 4.2 and 5 of our Terms Abstract: Surgical site infection (SSI) is one of the most common complications following cesarean section, and has an incidence of 3%–15%. It places physical and emotional burdens on the mother herself and a significant financial burden on the health care system. Moreover, SSI is associated with a maternal mortality rate of up to 3%. With the global increase in cesarean section rate, it is expected that the occurrence of SSI will increase in parallel, hence its clinical significance. Given its substantial implications, recognizing the consequences and developing strategies to diagnose, prevent, and treat SSI are essential for reducing postcesarean morbidity and mortality. Optimization of maternal comorbidities, appropriate antibiotic prophy-laxis, and evidence-based surgical techniques are some of the practices proven to be effective in reducing the incidence of SSI. In this review, we describe the biological mechanism of SSI and risk factors for its occurrence and summarize recent key clinical trials investigating preopera-tive, intraoperative, and postoperative practices to reduce SSI incidence. It is prudent that the surgical team who perform cesarean sections be familiar with these practices and apply them as needed to minimize maternal morbidity and mortality related to SSI.
Bullying in Canada in the 21st Century: The Moral Obligations of Parents, Teachers, Schools and Governments

Despite an abundance of evidence-based intervention programmes available to schools across the country, childhood bullying persists in Canada. This paper looks at various types of bullying behaviour and its often devastating and far-reaching effects. It examines the common characteristics of children who bully as well as the reasons for, and causes of, bullying behaviour and summons more heightened attention to its root causes namely poverty, homelessness and disconnection. The moral obligations of parents, teachers, schools and governments and their roles as team players in raising sociable, compassionate and confident moral citizens in a world in which bullying behaviour is not only unacceptable but unthinkable, is also discussed.
Concept mining from natural language texts

WordNet dictionaries are a commonly used resource in the NLP field. Many papers discuss the theme of WordNet dictionaries, but the processes devoted to their automated construction have still much space for improvement. Many of them are based on machine translation strategies converting the dictionaries from one language to another. Most of them have one attribute in common: they use the knowledge about the language used in the form of dictionaries or even simple grammar parsers. In WordNet dictionaries, terms are represented in the form of concept hierarchies (hypernyms, hyponyms, .). Since the ALOC approach was used to achieve similar concept structures, we can assume that it could also be used in the area of automated WordNet dictionary construction. This paper discusses such application of ALOC, in the form of correct assignment of new concepts into the existing WordNet hierarchy.
GNSS Receiver Based on a SDR Architecture Using FPGA Devices

This paper presents the development of a FPGA based GNSS receiver. The developed prototype is based on a Software Radio Architecture and integrates all the main GPS signal processing algorithms as IP modules do. Furthermore, description of a developed system for the acquisition, tracking and position computation algorithms is described. The obtained results display that the positioning obtained with this prototype is closer to the real user position.
National programmes for validating physician competence and fitness for practice: a scoping review

Objective To explore and categorise the state of existing literature for national programmes designed to affirm or establish the continuing competence of physicians. Design Scoping review. Data sources MEDLINE, ERIC, Sociological Abstracts, web/grey literature (2000–2014). Selection Included when a record described a (1) national-level physician validation system, (2) recognised as a system for affirming competence and (3) reported relevant data. Data extraction Using bibliographic software, title and abstracts were reviewed using an assessment matrix to ensure duplicate, paired screening. Dyads included both a methodologist and content expert on each assessment, reflective of evidence-informed best practices to decrease errors. Results 45 reports were included. Publication dates ranged from 2002 to 2014 with the majority of publications occurring in the previous six years (n=35). Country of origin—defined as that of the primary author—included the USA (N=32), the UK (N=8), Canada (N=3), Kuwait (N=1) and Australia (N=1). Three broad themes emerged from this heterogeneous data set: contemporary national programmes, contextual factors and terminological consistency. Four national physician validation systems emerged from the data: the American Board of Medical Specialties Maintenance of Certification Program, the Federation of State Medical Boards Maintenance of Licensure Program, the Canadian Revalidation Program and the UK Revalidation Program. Three contextual factors emerged as stimuli for the implementation of national validation systems: medical regulation, quality of care and professional competence. Finally, great variation among the definitions of key terms was identified. Conclusions There is an emerging literature focusing on national physician validation systems. Four major systems have been implemented in recent years and it is anticipated that more will follow. Much of this work is descriptive, and gaps exist for the extent to which systems build on current evidence or theory. Terminology is highly variable across programmes for validating physician competence and fitness for practice.