Miracle-dz/UniFAR-FTUs huggingface dataset:
A spatio-temporal multimedia big data framework for a large crowd

Crowdsourced multimedia data poses several challenges when it is collected, stored, indexed, retrieved, and visualized. Examples of crowd source multimedia data are social sensors, vehicle sensors, physical sensors, human sensors, etc. Analyzing such multimodal and diversified crowdsourced data provides very rich understanding about the need of individuals within a crowd. Such understanding makes it possible to tailor services to individuals' needs, also called context-aware services. In this paper, we propose a spatial multimedia big data framework that can collect multimedia data from 1) a very large crowd equipped with multi-sensory smartphones, 2) vehicles, and 3) social networks. A set of multimedia services are offered to users to support their spatio-temporal activities. These include but not limited to 1) simple user interfaces to utilize multimedia services for instant guidance, 2) navigation to points of interests (POI), and 3) efficient and cost effective intra-city rides to users. The big data framework is designed to handle a very large number of multimedia spatio-temporal queries in real-time. The system is a pilot project and will be deployed during the event of Hajj 2015 when over three million pilgrims from all over the world will visit Makkah, Saudi Arabia to perform their Hajj rituals.
Strategic Communication: Prices Versus Quantities

We examine how cheap talk communication between managers within the same firm depends on the type of decisions that the firm makes. A firm consists of a headquarters and two operating divisions. Headquarters is unbiased but does not know the demand conditions in the divisions' markets. Each division manager knows the demand conditions in his market but is also biased toward his division. The division managers communicate with headquarters, which then sets either the prices or quantities for each division. The quality of communication depends on whether headquarters sets prices or quantities. This is the case even though, once communication has taken place, expected profits are the same whether headquarters sets prices or quantities. (JEL: D21, D83, L20) (c) 2010 by the European Economic Association.
Untwisting the Caenorhabditis elegans embryo

The nematode Caenorhabditis elegans possesses a simple embryonic nervous system with few enough neurons that the growth of each cell could be followed to provide a systems-level view of development. However, studies of single cell development have largely been conducted in fixed or pre-twitching live embryos, because of technical difficulties associated with embryo movement in late embryogenesis. We present open-source untwisting and annotation software (http://mipav.cit.nih.gov/plugin_jws/mipav_worm_plugin.php) that allows the investigation of neurodevelopmental events in late embryogenesis and apply it to track the 3D positions of seam cell nuclei, neurons, and neurites in multiple elongating embryos. We also provide a tutorial describing how to use the software (Supplementary file 1) and a detailed description of the untwisting algorithm (Appendix). The detailed positional information we obtained enabled us to develop a composite model showing movement of these cells and neurites in an 'average' worm embryo. The untwisting and cell tracking capabilities of our method provide a foundation on which to catalog C. elegans neurodevelopment, allowing interrogation of developmental events in previously inaccessible periods of embryogenesis. DOI: http://dx.doi. org/10.7554/eLife.10070. 001
Perceptions of supervisor support: Resolving paradoxical patterns across gender and race

This work reconciles previous discrepancies regarding when and how the demographic composition of supervisor–subordinate dyads relates to perceived supervisor support. We draw from social identity theory to argue that building relationships with higher-status group members, while distancing oneself from the lower-status group, is a contextually induced way female and racial minority employees may cope with identity threat in the workplace. Our results supported the hypotheses, indicating that this self-distancing effect via reduced perceived supervisor support only emerges in settings where gender or racial identities may be considered threatened (in organizations with climates of higher perceived gender inequity, Study 1; or climates of higher perceived diversity inequity, Study 2). Such results are particularly important and timely given the recent ample attention in popular media and academic outlets regarding the ‘queen bee’ effect, the ‘crabs in the barrel’ mentality, and diversity-valuing behaviour of leaders. The current research suggests that such behaviours are not generalizable to all female or minority employees; rather, this effect seems to be context-driven. Practitioner points Organizational climates that are higher in gender and/or diversity inequity may bring about negative in-group behaviours between supervisors and subordinates. To increase perceptions of supervisor support, especially among traditionally low-status employees, organizations should improve their diversity climates to be more inclusive for all employees. Building active mentoring programmes for under-represented groups and increasing the number of women and non-White employees in senior positions, while emphasizing equal opportunity for all employees, are some ways organizations can reduce perceptions of gender and diversity inequity. A career-lattice approach to employee career development would allow employees to engage in more lateral transfers – enabling them to gain diverse skills, be exposed to multiple mentors, and to remove themselves from a potentially harmful supervisor–subordinate relationship.
A Comparative Study of Path Performance Metrics Predictors

Using quality-of-service (QoS) metrics for Internet traffic is expected to improve greatly the performance of many network enabled applications, such as Voice-over-IP(VoIP) and video conferencing. However, it is not possible to constantly measure path performance metrics (PPMs) such as delay and throughput without interfering with the network. In this work, we focus on PPMs measurement scalability by considering machine learning techniques to estimate predictive models from past PPMs observations. Using real data collected from PlanetLab, we provide a comparison between three different predictors: AR(MA) models, Kalman filters and support vector machines (SVMs). Some predictors use delay and throughput jointly to take advantage of the possible relationship between PPMs, while other predictors consider PPMs individually. Our current results illustrate that the best performing model is an individual SVM specific to each time series. Overall, delay can be predicted with very good accuracy while accurate forecasting of throughput remains an open problem.
Unambiguous constrained Automata

The class of languages captured by Constrained Automata (CA) that are unambiguous is shown to possess more closure properties than the provably weaker class captured by deterministic CA. Problems decidable for deterministic CA are nonetheless shown to remain decidable for unambiguous CA, and testing for regularity is added to this set of decidable problems. Unambiguous CA are then shown incomparable with deterministic reversal-bounded machines in terms of expressivity, and a deterministic model equivalent to unambiguous CA is identified.
Data Word Length Reduction for Low-Power DSP Software

Data Word Length Reduction for Low-Power DSP Software Kyungtae Han Abstract The increasing demand for portable computing accelerates the study of minimizing power dissipation. Most power in processes is consumed by the switching activity of capacitance. The switching power can be reduced by not only minimizing hardware but also optimizing software. Key papers for low power techniques of hardware and software are surveyed. Power analysis and minimization techniques make it possible to optimize software power. Variable word lengths in arithmetic operations without any change of hardware can be a promising software power minimization technique. The objective of this work is to analyze and minimize power dissipation of digital signal processing (DSP) blocks at software level. Preliminary results of an array multiplier with reduced word lengths and plans are presented. This research will have contribution to prolong battery life in portable DSP applications.
Time of Progression to Osteopenia/Osteoporosis in Chronically HIV-Infected Patients: Screening DXA Scan

Background Algorithms for bone mineral density (BMD) management in HIV-infected patients are lacking. Our objective was to assess how often a dual-energy x-ray absorptiometry (DXA) scan should be performed by assessing time of progression to osteopenia/osteoporosis. Methods All DXA scans performed between 2000 and 2009 from HIV-infected patients with at least two DXA were included. Time to an event (osteopenia and osteoporosis) was assessed using the Kaplan–Meier method. Strata (tertiles) were defined using baseline minimum T scores. Differences between strata in time to an event were compared with the log-rank test. Results Of 391 patients (1,639 DXAs), 49.6% had osteopenia and 21.7% osteoporosis at their first DXA scan. Of the 112 (28.6%) with normal BMD, 35.7% progressed to osteopenia; median progression time was 6.7 years. These patients were stratified: “low-risk" (baseline minimum T score >−0.2 SD), “middle-risk" (between −0.2 and −0.6 SD), and “high-risk" (from −0.6 to −1 SD); median progression time to osteopenia was 8.7, >7.2, and 1.7 years, respectively (p<0.0001). Of patients with osteopenia, 23.7% progressed to osteoporosis; median progression time was >8.5 years. Progression time was >8.2 years in “low-risk" tertile (T score between −1.1 and −1.6 SD), >8.5 years in “middle-risk" (between −1.6 and −2), and 3.2 years in “high-risk" (from −2 to −2.4) (p<0.0001). Conclusions Our results may help to define the BMD testing interval. The lowest T score tertiles would suggest recommending a subsequent DXA in 1–2 years; in the highest tertiles, ≥6 years. Early intervention in patients with bone demineralization could reduce fracture–related morbidity/mortality.
Asymptotically optimal approximation of single qubit unitaries by Clifford and T circuits using a constant number of ancillary qubits

Decomposing unitaries into a sequence of elementary operations is at the core of quantum computing. Information theoretic arguments show that approximating a random unitary with precision ε requires Ω(log(1/ε)) gates. Prior to our work, the state of the art in approximating a single qubit unitary included the Solovay-Kitaev algorithm that requires O(log(3+δ)(1/ε)) gates and does not use ancillae and the phase kickback approach that requires O(log(2)(1/ε)loglog(1/ε)) gates but uses O(log(2)(1/ε)) ancillae. Both algorithms feature upper bounds that are far from the information theoretic lower bound. In this Letter, we report an algorithm that saturates the lower bound, and as such it guarantees asymptotic optimality. In particular, we present an algorithm for building a circuit that approximates single qubit unitaries with precision ε using O(log(1/ε)) Clifford and T gates and employing up to two ancillary qubits. We connect the unitary approximation problem to the problem of constructing solutions corresponding to Lagrange's four-square theorem, and thereby develop an algorithm for computing an approximating circuit using an average of O(log(2)(1/ε)loglog(1/ε)) operations with integers.
The Endocrine Milieu and CD4 T-Lymphocyte Polarization during Pregnancy

Acceptance of the fetal semi-allograft by the mother’s immune system has become the focus of intensive research. CD4+ T cells are important actors in the establishment of pregnancy. Th1/Th2 paradigm has been expanded to include CD4+ regulatory T (Treg) and T helper 17 (Th17) cells. Pregnancy hormones exert very significant modulatory properties on the maternal immune system. In this review, we describe mechanisms by which the endocrine milieu modulates CD4 T cell polarization during pregnancy. We first focused on Treg and Th17 cells and on their importance for pregnancy. Secondly, we review the effects of pregnancy hormones [progesterone (P4) and estradiol (E2)] on immune cells previously described, with a particular attention to human chorionic gonadotropin (hCG). The importance of Treg cells for pregnancy is evidenced. They are recruited before implantation and are essential for pregnancy maintenance. Decreased number or less efficient Treg cells are implicated in fertility disorders. As for Th17 cells, the few available studies suggest that they have a negative impact on fertility. Th17 frequency is increased in infertile patients. With the combination of its pro-effects on Th2 and Treg cells and anti-effects on Th1 and Th17 cells, P4 contributes to establishment of a favorable environment for pregnancy. E2 effects are more dependent on the context but it seems that E2 promotes Treg and Th2 cells while it inhibits Th1 cells. hCG positively influences activities of Treg and uterine natural killer cells. This embryo signal is an essential actor for the success of pregnancy, both as the endocrine factor regulating P4 secretion by the ovarian corpus luteum, but also as a paracrine agent during implantation as well as an angiogenic and immunologic mediator during the course of gestation. Luteinizing hormone (LH) immune properties begin to be studied but its positive impact on Treg cells suggests that LH could be a considerable immunomodulator in the mouse.
MONITORING VEGETATION DYNAMICS USING MERIS FUSED IMAGES

The MEdium Resolution Imaging Spectrometer (MERIS) can be used to monitor vegetation dynamics at regional to global scales. However, the spatial resolutions provided by this sensor (300 or 1200 m) might not be appropriate to monitor fragmented landscapes. This is why the synergistic use of MERIS full resolution (300 m) and a high spatial resolution land use/land cover database (25 m) is studied in this paper. An unmixing-based data fusion approach was used to produce images that have the spectral and temporal resolutions provided by MERIS and a Landsat-like spatial resolution. The central part of The Netherlands was selected to illustrate this approach. Seven MERIS full resolution and one Landsat TM image were available over this area too. The radiometric characteristics of the fused images were evaluated at 25 and at 300 m. After this quantitative quality assessment, the best fused images were used to compute MTCI and MGVI profiles for the main land cover types present in the study area.
Theatre Elicitation: developing a potentially child-friendly method with children aged 8–12

ABSTRACT This article discusses the growing body of literature published in Children Geographies on the importance of involving children in research processes. Inspired by participatory creative methods such as photo elicitation and popular/forum theatre, we have developed a potentially child-friendly tool referred to as Theatre Elicitation (TE). The objective of TE is to use theatre forms as a means of data collection in the context of a negotiated research process. In a pilot project in which we explore TE, children shared their perceptions of happiness. This was inspired by a UNICEF Report [2007. Child Poverty in Perspective: An Overview of Child Well-being in Rich Countries. Innocenti Report Card 7. Florence: UNICEF Innocenti Research Centre] that listed ‘Dutch children’ as the happiest of the world. The focus of this article is the development of TE as an interactive research tool. Insights were gained into the meaning of ‘child-friendly’ research, shifting power relations between children, peers and adults, and how children’s own positioning in lived experiences contextualized concepts such as ‘Dutch children’.
Exploring transitions in notions of identity as perceived by beginning post-compulsory teachers

Abstract This paper reports on Phase Two of a small-scale qualitative research project. Phase One (2015–2016) focused on pre-service student teachers’ perceptions of observation and feedback in relation to their developing identity as teachers. In Phase Two, two previous participants reflected on the research findings as qualified and beginning teachers. New participants were invited to contribute their perspectives of the transition they had made from the Postgraduate Certificate in Post-Compulsory Education (PGCE PCE) one-year full-time course to their first year of teaching. Phase Two considers constructs of teacher identity and theoretical models of communities of practice and ecological learning systems. Participants reviewed transitions from PGCE PCE into their first year of teaching in relation to a continuum of practice that saw them taking increased levels of ownership of their development. They described the extent to which and the ways in which they identified themselves with the teacher role and as members of a community at work. Applications of the community of practice model were discussed and occasionally compared unfavourably to the community of practice context of the PGCE PCE course. Community of practice concepts such as ‘membership’ and ‘validation’ are re-explored in this paper.
HiChIP: efficient and sensitive analysis of protein-directed genome architecture

Genome conformation is central to gene control but challenging to interrogate. Here we present HiChIP, a protein-centric chromatin conformation method. HiChIP improves the yield of conformation-informative reads by over 10-fold and lowers the input requirement over 100-fold relative to that of ChIA-PET. HiChIP of cohesin reveals multiscale genome architecture with greater signal-to-background ratios than those of in situ Hi-C.
Obesity, Visceral Fat, and NAFLD: Querying the Role of Adipokines in the Progression of Nonalcoholic Fatty Liver Disease

Nonalcoholic fatty liver disease (NAFLD) represents a spectrum of clinicopathologic conditions ranging from steatosis alone to nonalcoholic steatohepatitis (NASH), with varying risks for progression to cirrhosis and hepatocellular carcinoma. There is mounting evidence that NAFLD not only complicates obesity, but also perpetuates its metabolic consequences. Critical event that leads to progressive liver injury in NAFLD is unknown. Obesity reflects a generalized proinflammatory state with its increased inflammatory markers like C reactive protein, IL-6, IL-8, IL-10, PAI-1, TNF-α, and hepatocyte growth factor. The elevated production of these adipokines is increasingly considered to be important in the development of diseases linked to obesity and the metabolic syndrome. Disordered cytokine production is likely to play a role in the pathogenesis of NAFLD. There is no effective treatment for NAFLD, though weight loss may halt disease progression and revert histological changes, the underlying mechanism remaining elusive. All stages of the disease pathway from prevention, early identification/diagnosis, and treatment require an understanding of the pathogenesis of liver injury in NAFLD.
Epithelial-mesenchymal transition in proliferative vitreoretinopathy: intermediate filament protein expression in retinal pigment epithelial cells.

PURPOSE To improve our understanding of how retinal pigment epithelial (RPE) cells behave in vivo and to establish similarities with dedifferentiation and adaptive events observed in RPE cells cultured under simulated intraocular pathologic conditions. At the same time, to examine the origin of epithelioid-shaped and fibroblast/fusiform-shaped cells in epiretinal membranes (ERM) from proliferative vitreoretinopathy (PVR). METHODS Cells of ERM were studied by electron-immunocytochemical techniques, using simple, double, and triple immunostaining for cytokeratins (CK), vimentin (Vim), and glial fibrillary acidic protein (GFAP). Ultrastructural morphology analysis was also carried out. Adult human RPE cells were obtained and cultured with normal and pathologic vitreous from proliferative vitreoretinal disorders, subretinal fluid aspirates from retinal detachment, and normal human serum. Their cytoskeleton was fractionated at 7 (early cultures) and 24 (late cultures) days of culture, electrophoresed, immunoblotted for intermediate filament proteins, and quantified by densitometric analysis for each condition. Changes in phenotype characteristics were also evaluated. RESULTS Epithelioid-shaped and fibroblast/fusiform-shaped cells, resembling RPE cells, expressed CK-Vim-GFAP simultaneously as intermediate filament proteins in their cytoskeleton. RPE cells in culture also expressed CK-Vim-GFAP and changed from an epithelial shape to a migratory fibroblast/fusiform-shaped phenotype in the presence of subretinal fluid aspirates and pathologic vitreous from proliferative intraocular disorders. In simulated cultures of proliferative intraocular disorders, cells decreased or retained their CK7, CK8, and CK18, retained Vim, and increased CK19 and GFAP, while their mesenchymal morphology became clearer over time. CONCLUSIONS Studies of intermediate filament proteins in vivo suggest that dedifferentiation occurs in RPE cells in ERM. Dedifferentiated RPE cells may be responsible for epithelioid-like and fibroblast/fusiform-like cells. Furthermore, changes in intermediate filament protein levels were observed in RPE cells in simulated cultures of proliferative intraocular disorders. These changes were linked to cells acquiring a mesenchymal migratory, phenotype. Results indicate that the dedifferentiation of RPE cells occurs both in vivo and in vitro and that it can be explained as an epithelial-mesenchymal transition.
Motor and gait improvement in patients with incomplete spinal cord injury induced by high-frequency repetitive transcranial magnetic stimulation.

OBJECTIVE To assess the effect of high-frequency repetitive transcranial magnetic stimulation (rTMS) on lower extremities motor score (LEMS) and gait in patients with motor incomplete spinal cord injury (SCI). METHOD The prospective longitudinal randomized, double-blind study assessed 17 SCI patients ASIA D. We assessed LEMS, modified Ashworth Scale (MAS), 10-m walking test (10MWT), Walking Index for SCI (WISCI II) scale, step length, cadence, and Timed Up and Go (TUG) test at baseline, after the last of 15 daily sessions of rTMS and 2 weeks later. Patients were randomized to active rTMS or sham stimulation. Three patients from the initial group of 10 randomized to sham stimulation entered the active rTMS group after a 3-week washout period. Therefore a total of 10 patients completed each study condition. Both groups were homogeneous for age, gender, time since injury, etiology, and ASIA scale. Active rTMS consisted of 15 days of daily sessions of 20 trains of 40 pulses at 20 Hz and an intensity of 90% of resting motor threshold. rTMS was applied with a double cone coil to the leg motor area. RESULTS There was a significant improvement in LEMS in the active group (28.4 at baseline and 33.2 after stimulation; P = .004) but not in the sham group (29.6 at baseline, and 30.9 after stimulation; P = .6). The active group also showed significant improvements in the MAS, 10MWT, cadence, step length, and TUG, and these improvements were maintained 2 weeks later. Following sham stimulation, significant improvement was found only for step length and TUG. No significant changes were observed in the WISCI II scale in either group. CONCLUSION High-frequency rTMS over the leg motor area can improve LEMS, spasticity, and gait in patients with motor incomplete SCI.