Miracle-dz/UniFAR-FTUs huggingface dataset:
Assessment of Open-Angle Glaucoma Peripapillary and Macular Choroidal Thickness Using Swept-Source Optical Coherence Tomography (SS-OCT)

Objective To compare peripapillary and macular choroidal thickness (PCT and MCT) between open-angle glaucoma (OAG) and normal controls using swept-source optical coherence tomography (SS-OCT), and to evaluate global and localized relationships between choroidal thickness and various factors in OAG, also using SS-OCT. Methods In this cross-sectional comparative study, 134 OAG patients and 73 normal controls were examined. PCT (global, 12 clock-hour sectors), MCT (global, six sectors) were measured by SS-OCT. The difference in choroidal thickness between the OAG patients and the normal controls was analyzed. The relationships between choroidal thickness and various factors including age, sex, spherical equivalent (SE), axial length (AXL), central corneal thickness (CCT), intraocular pressure (IOP), peripapillary retinal nerve fiber layer thickness (pRNFLT), visual field mean deviation (MD), ganglion cell-inner plexiform layer thickness (GCIPLT), and disc area were analyzed by univariate and multivariate linear regression. Global and regional analyses were performed in 12 segments of the peripapillary circle and in six sectors of the macula. Results There were significant differences in global PCT and MCT between the OAG patients and the normal controls (115.22±41.17 vs. 138.89±44.70, P<0.001), (184.36±57.15 vs. 209.25±61.11, P = 0.004). The difference in global PCT remained, both after adjusting for age, AXL (117.08±3.45 vs. 135.47±4.70, P = 0.002) and also after adjusting for age, AXL, disc area (117.46±3.46 vs. 135.67±4.67, P = 0.002). But the difference in global MCT did not remain after adjusting for age, AXL, SE (188.18±4.46 vs. 202.25±6.08, P = 0.066). PCT showed significant differences between the groups in all of the 12 clock-hour sectors. These differences remained after adjusting for age, AXL and for age, AXL, disc area, with the exception of the 10 o’clock (o/c) sector. MCT in six sectors showed differences between the two groups, but they did not remain after adjusting for age, AXL, SE. In a multivariate regression analysis of the OAG patients, global PCT showed correlations with age (β = -1.18, P = 0.001), AXL (β = -14.01, P<0.001), and disc area (β = -16.67, P = 0.026). Global MCT, meanwhile, showed a significant correlation with age (β = -1.92, P<0.001), AXL. (β = -21.97, P<0.001). Choroidal thickness did not show any global or localized relationship with glaucoma severity in the OAG patients. Conclusions The global and all 12 clock-hour PCT, with the exception of the 10 o/c sector, were thinner in OAG; however, they did not show any correlation with glaucoma severity. Possible roles of PCT in glaucoma pathogenesis should be investigated further.
Epistemic Feelings, Epistemic Emotions: Review and Introduction to the Focus Section

Philosophers of mind and epistemologists are increasingly making room in their theories for epistemic emotions (E-emotions) and, drawing on metacognition research in psychology, epistemic – or noetic or metacognitive – feelings (E-feelings). Since philoso- phers have only recently begun to draw on empirical research on E-feelings, in particular, we begin by providing a general characterization of E-feelings (section 1) and reviewing some highlights of relevant research (section 2). We then turn to philosophical work on E-feelings and E-emotions, situating the contributions to the focus section (two articles devoted to E-feelings and two devoted to E-emotions) with respect to both the existing literature and each other (section 3). We conclude by briefly describing some promising avenues for further philosophical research on E-feelings and E-emotions (section 4).
Clozing in on comprehension: The Cloze Story Map

Development of the Cloze Story Map (CSM), whose use will be described here, is rooted in the theory and re search related to the cloze technique, semantic and story mapping, story grammars, and organizational the ory? all important cognitive ap proaches to the teaching of reading comprehension. A CSM provides stu dents with a framework for organiz ing, monitoring, and integrating information obtained from text. By ap plying their prior knowledge, their knowledge of story structure, and rele vant information acquired from read ing in a certain way, students are able to fill in the missing information called for by the CSM. Doing so leads them to integrate their old and new knowl edge about the story topic, emphasiz ing that reading is done to build meaning out of text. This article presents the back ground, design, research, and possible uses for the Cloze Story Map in the el ementary classroom.
Lessons From Markey et al. (2015) and Bushman et al. (2015): Sensationalism and Integrity in Media Research

This article presents a response to the comment by B. J. Bushman, D. Romer, and P. E. Jamieson (2015). This reply addresses 2 issues raised by the commenters. First, they claim they and others have not made sensationalistic statements linking violent media to horrific acts of real-world violence. In response, we supply numerous examples of sensationalistic statements made by them and others. Second, they claim they did not expect violence in films to be related to violent behavior among adults, but only among youths. However, by examining homicide arrests and homicide gun mortality rates among youths, we found that as films have become increasingly violent over time, both homicide arrests and gun-related homicides have tended to decrease among this age group.
Coherence for Skew-Monoidal Categories

We motivate a variation (due to K. Szlachof monoidal categories called skew-monoidal cat- egories where the unital and associativity laws are not required to be isomorphisms, only natural transformations. Coherence has to be formulated differently than in the well-known monoidal case. In my (to my knowledge new) version it becomes a statement of uniqueness of normalizing rewrites. We present a proof of this coherence proof and also formalize it fully in the dependently typed pro- gramming language Agda.
Impact of non-local filtering on 3D reconstruction from tomographic SAR data

In this paper, we introduce two spatially adaptive covariance filtering methods and evaluate their effect on scatterer separation and height estimation from tomographic SAR. The first one was previously introduced for polarimetric data and uses pixel similarities based on Riemannian distances between covariance matrices. The second one is a new method extending the previous one to patch-based similarities. We show the importance of spatial adaptivity in covariance estimation by comparing the 3D reconstructions obtained with our nonlocal filters and the boxcar filter. Our experiments on simulated and L-band experimental data show the ability of the non-local filters to improve the height estimation and scatterer separation in layover areas thanks to their smoothing and edge preserving properties.
Arabidopsis cytosolic acyl-CoA-binding proteins ACBP4, ACBP5 and ACBP6 have overlapping but distinct roles in seed development

Eukaryotic cytosolic ACBPs (acyl-CoA-binding proteins) bind acyl-CoA esters and maintain a cytosolic acyl-CoA pool, but the thermodynamics of their protein–lipid interactions and physiological relevance in plants are not well understood. Arabidopsis has three cytosolic ACBPs which have been identified as AtACBP4, AtACBP5 and AtACBP6, and microarray data indicated that all of them are expressed in seeds; AtACBP4 is expressed in early embryogenesis, whereas AtACBP5 is expressed later. ITC (isothermal titration calorimetry) in combination with transgenic Arabidopsis lines were used to investigate the roles of these three ACBPs from Arabidopsis thaliana. The dissociation constants, stoichiometry and enthalpy change of AtACBP interactions with various acyl-CoA esters were determined using ITC. Strong binding of recombinant (r) AtACBP6 with long-chain acyl-CoA (C16- to C18-CoA) esters was observed with dissociation constants in the nanomolar range. However, the affinity of rAtACBP4 and rAtACBP5 to these acyl-CoA esters was much weaker (dissociation constants in the micromolar range), suggesting that they interact with acyl-CoA esters differently from rAtACBP6. When transgenic Arabidopsis expressing AtACBP6pro::GUS was generated, strong GUS (β-glucuronidase) expression in cotyledonary-staged embryos and seedlings prompted us to measure the acyl-CoA contents of the acbp6 mutant. This mutant accumulated higher levels of C18:1-CoA and C18:1- and C18:2-CoAs in cotyledonary-staged embryos and seedlings, respectively, in comparison with the wild type. The acbp4acbp5acbp6 mutant showed the lightest seed weight and highest sensitivity to abscisic acid during germination, suggesting their physiological functions in seeds.
Genome-wide association study of 107 phenotypes in Arabidopsis thaliana inbred lines

Susanna Atwell*, Yu S. Huang*, Bjarni J. Vilhjálmsson*, Glenda Willems*, Matthew Horton, Yan Li, Dazhe Meng, Alexander Platt, Aaron M. Tarone, Tina T. Hu, Rong Jiang, N. Wayan Muliyati, Xu Zhang, Muhammad Ali Amer, Ivan Baxter, Benjamin Brachi, Joanne Chory, Caroline Dean, Marilyne Debieu, Juliette de Meaux, Joseph R. Ecker, Nathalie Faure, Joel M. Kniskern, Jonathan D. G. Jones, Todd Michael, Adnane Nemri, Fabrice Roux, David E. Salt, Chunlao Tang, Marco Todesco, M. Brian Traw, Detlef Weigel, Paul Marjoram, Justin O. Borevitz, Joy Bergelson & Magnus Nordborg
Sphaleron-induced baryon-number nonconservation and a constraint on Majorana neutrino masses.

We point out that the baryon-number asymmetry in the Universe is erased by the sphaleron effect just below the electroweak phase transition irrespective of the primordial baryon- and lepton-number asymmetry, if there exists a Majorana-type interaction. The requirement to avoid this happening leads to the condition that ${m}_{\ensuremath{\nu}} (\mathrm{Majorana})l50$ keV for all species of neutrions, regardless of whether or not neutrinos are stable.
High-Resolution Time-Frequency Spectrum-Based Lung Function Test from a Smartphone Microphone

In this paper, a smartphone-based lung function test, developed to estimate lung function parameters using a high-resolution time-frequency spectrum from a smartphone built-in microphone is presented. A method of estimation of the forced expiratory volume in 1 s divided by forced vital capacity (FEV1/FVC) based on the variable frequency complex demodulation method (VFCDM) is first proposed. We evaluated our proposed method on 26 subjects, including 13 healthy subjects and 13 chronic obstructive pulmonary disease (COPD) patients, by comparing with the parameters clinically obtained from pulmonary function tests (PFTs). For the healthy subjects, we found that an absolute error (AE) and a root mean squared error (RMSE) of the FEV1/FVC ratio were 4.49% ± 3.38% and 5.54%, respectively. For the COPD patients, we found that AE and RMSE from COPD patients were 10.30% ± 10.59% and 14.48%, respectively. For both groups, we compared the results using the continuous wavelet transform (CWT) and short-time Fourier transform (STFT), and found that VFCDM was superior to CWT and STFT. Further, to estimate other parameters, including forced vital capacity (FVC), forced expiratory volume in 1 s (FEV1), and peak expiratory flow (PEF), regression analysis was conducted to establish a linear transformation. However, the parameters FVC, FEV1, and PEF had correlation factor r values of 0.323, 0.275, and −0.257, respectively, while FEV1/FVC had an r value of 0.814. The results obtained suggest that only the FEV1/FVC ratio can be accurately estimated from a smartphone built-in microphone. The other parameters, including FVC, FEV1, and PEF, were subjective and dependent on the subject’s familiarization with the test and performance of forced exhalation toward the microphone.
Patterns of Colorectal Cancer Screening Uptake among Men and Women in the United States

Objective: The purpose of this report is to examine (a) gender-specific correlates of colorectal cancer test use using recent national data from 2003 and (b) patterns of colorectal cancer screening by gender and test modality over time. Methods: We analyze data from the 1987, 1992, 1998, 2000, and 2003 National Health Interview Surveys. Our sample consists of men and women ≥50 years never diagnosed with colorectal cancer and who reported a recent fecal occult blood test and/or endoscopy. Results: In 2003, both men and women reported higher rates of colonoscopy (32.2% and 29.8%, respectively) than use of FOBT (16.1% and 15.3%, respectively) or sigmoidoscopy (7.6% and 5.9%, respectively). Men reported higher use of endoscopy than women if they had a usual source of health care, had talked to a general doctor, and had two to five visits to the doctor in the past year. Men and women 65 years and older had higher rates of any recommended colorectal cancer test (55.8% and 48.5%, respectively) than persons 50 to 64 years (males, 41.0%; females, 31.4%). Use of colorectal cancer tests also was higher among both genders if they were not Hispanic, had higher educational attainment, were former smokers, had health insurance or a usual source of care, or if they talked to a general doctor. Recent use of colorectal cancer tests has increased since 2000 for both women and men largely due to increased use of colonoscopy. Conclusions: Colorectal cancer testing is increasing for both men and women, although the prevalence of testing remains higher in men. Our data support previous findings documenting socioeconomic disparities in colorectal cancer test use. Access barriers to screening could be particularly difficult to overcome if colonoscopy becomes the preferred colorectal cancer screening modality. (Cancer Epidemiol Biomarkers Prev 2006;15(2):389–94)
The placement of secondary school students with Statements of special educational needs in the more diversified system of English secondary schooling

This article examines the pattern of placement of students with significant special educational needs at Statement and School Action Plus levels in English secondary schools, comparing sponsored and converter academies, maintained schools and the newly created free schools, studio schools and university technical colleges for 2013 and 2014. The analysis shows a clear pattern of differences: converter academies (which are governed by their own governing body) had significantly lower proportions of students with significant special educational needs overall than maintained (those remaining under local authority management) and sponsored academies (those considered to be weak/failing schools forced to become academies with outside sponsors that oversee the schools). There was a similar pattern of findings for most areas of special educational needs, except visual impairment and autistic spectrum disorder. The pattern of placement of students with Statements in the newly created free schools also showed that some free schools have unusually high proportions of students with special educational needs. These findings are discussed in terms of the increasing stratification of English secondary schools and the potential of small secondary schools to be more inclusive.
An Exploratory Investigation on the Use of Closed-Loop Electrical Stimulation to Assist Individuals with Stroke to Perform Fine Movements with Their Hemiparetic Arm

Stroke is the leading cause of upper limb impairments resulting in disability. Modern rehabilitation includes training with robotic exoskeletons and functional electrical stimulation (FES). However, there is a gap in knowledge to define the detailed use of FES in stroke rehabilitation. In this paper, we explore applying closed-loop FES to the upper extremities of healthy volunteers and individuals with a hemiparetic arm resulting from stroke. We used a set of gyroscopes to monitor arm movements and used a non-linear controller, namely, the robust integral of the sign of the error (RISE), to assess the viability of controlling FES in closed loop. Further, we explored the application of closed-loop FES in improving functional tasks performed by individuals with stroke. Four healthy individuals of ages 27–32 years old and five individuals with stroke of ages 61–83 years old participated in this study. We used the Rehastim FES unit (Hasomed Ltd.) with real-time modulation of pulse width and amplitude. Both healthy and stroke individuals were tested in RISE-controlled single and multi-joint upper limb motions following first a sinusoidal trajectory. Individuals with stroke were also asked to perform the following functional tasks: picking up a basket, picking and placing an object on a table, cutting a pizza, pulling back a chair, eating with a spoon, as well as using a stapler and grasping a pen. Healthy individuals were instructed to keep their arm relaxed during the experiment. Most individuals with stroke were able to follow the sinusoid trajectories with their arm joints under the sole excitation of the closed-loop-controlled FES. One individual with stroke, who was unable to perform any of the functional tasks independently, succeeded in completing all the tasks when FES was used. Three other individuals with stroke, who were unable to complete a few tasks independently, completed some of them when FES was used. The remaining stroke participant was able to complete all tasks with and without FES. Our results suggest that individuals with a low Fugl–Meyer score or a higher level of disability may benefit the most with the use of closed-loop-controlled FES.
Climate, traffic-related air pollutants, and asthma prevalence in middle-school children in taiwan.

This study compared the prevalence of asthma with climate and air pollutant data to determine the relationship between asthma prevalence and these factors. We conducted a nationwide survey of respiratory illness and symptoms in middle-school students in Taiwan. Lifetime prevalences of physician-diagnosed asthma and of typical symptoms of asthma were compared to air monitoring station data for temperature, relative humidity, sulfur dioxide, nitrogen oxides, ozone, carbon monoxide, and particulate matter with aerodynamic diameter [less than/equal to] 10 microm (PM(10)). A total of 331,686 nonsmoking children attended schools located within 2 km of 55 stations. Asthma prevalence rates adjusted for age, history of atopic eczema, and parental education were associated with nonsummer (June-August) temperature, winter (January-March) humidity, and traffic-related air pollution, especially carbon monoxide and nitrogen oxides, for both girls and boys. Nonsummer temperature, winter humidity, and traffic-related air pollution, especially carbon monoxide and nitrogen oxides, were positively associated with the prevalence of asthma in middle-school students in Taiwan. ImagesFigure 1Figure 2Figure 3Figure 4
Lattice paths below a line of rational slope

We analyze some enumerative and asymptotic properties of lattice paths below a line of rational slope. We illustrate our approach with Dyck paths under a line of slope $2/5$. This answers Knuth's problem $\#4$ from his "Flajolet lecture" during the conference "Analysis of Algorithms" (AofA'2014) in Paris in June 2014. Our approach extends the work of Banderier and Flajolet for asymptotics and enumeration of directed lattice paths to the case of generating functions involving several dominant singularities, and has applications to a full class of problems involving some "periodicities". A key ingredient in the proof is the generalization of an old trick by Knuth himself (for enumerating permutations sortable by a stack), promoted by Flajolet and others as the "kernel method". All the corresponding generating functions are algebraic, and they offer some new combinatorial identities, which can also be tackled in the A=B spirit of Wilf-Zeilberger-Petkovsek. We show how to obtain similar results for any rational slope. An interesting case are e.g. Dyck paths below the slope $2/3$ (this corresponds to the so called Duchon's club model), for which we solve a conjecture related to the asymptotics of the area below such lattice paths. Our work also gives access to lattice paths below an irrational slope (e.g. Dyck paths below $y=x/\sqrt{2}$), a problem that we study in a companion article.
Seeing Behind the Scene: Using Symmetry to Reason About Objects in Cluttered Environments

Symmetry is a common property shared by the majority of man-made objects. This paper presents a novel bottom-up approach for segmenting symmetric objects and recovering their symmetries from 3D pointclouds of natural scenes. Candidate rotational and reflectional symmetries are detected by fitting symmetry axes/planes to the geometry of the smooth surfaces extracted from the scene. Individual symmetries are used as constraints for the foreground segmentation problem that uses symmetry as a global grouping principle. Evaluation on a challenging dataset shows that our approach can reliably segment objects and extract their symmetries from incomplete 3D reconstructions of highly cluttered scenes, outperforming state-of-the-art methods by a wide margin.
Learning to improve path planning performance

In robotics, path planning refers to finding a short. collision-free path from an initial robot configuration to a desired configuratioin. It has to be fast to support real-time task-level robot programming. Unfortunately, current planning techniques are still too slow to be effective, as they often require several minutes, if not hours of computation. To remedy this situation, we present and analyze a learning algorithm that uses past experience to increase future performance. The algorithm relies on an existing path planner to provide solutions to difficult tasks. From these solutions, an evolving sparse network of useful robot configurations is learned to support faster planning. More generally, the algorithm provides a speedup-learning framework in which a slow but capable planner may be improved both cost-wise and capability-wise by a faster but less capable planner coupled with experience. The basic algorithm is suitable for stationary environments, and can be extended to accommodate changing environments with on-demand experience repair and object-attached experience abstraction. To analyze the algorithm, we characterize the situations in which the adaptive planner is useful, provide quantitative bounds to predict its behavior, and confirm our theoretical results with experiments in path planning of manipulators. Our algorithm and analysis are sufficiently, general that they may also be applied to other planning domains in which experience is useful.
Understanding White Privilege: Creating Pathways to Authentic Relationships Across Race

Chapter One: Beginning with Ourselves: The Importance of Doing Our Personal Work Chapter Two: What's In It For Us? Why We Would Explore What It Means to Be White Chapter Three: What Does It Mean to Be White? Chapter Four: Understanding White Privilege Chapter Five: How White Women Reinforce the Supremacy of Whiteness Chapter Six: Barriers to Clarity: What Keeps White People from Being Able to See Our Whiteness, and, Therefore, Our Privilege? Chapter Seven: Now that (I Think) I Understand White Privilege, What Do I Do? Chapter Eight: Talking about Race: What If They Call Me a Racist? Chapter Nine: Talking About Whiteness and Being White Chapter Ten: Becoming an Ally and Building Authentic Relationships Across Race: The Challenge and Necessity of Making Race Our Issue