Miracle-dz/UniFAR-FTUs huggingface dataset:
Inhibition of LDL Oxidation and Foam Cell Development of Tannin Methanol Extract from Citrus limon and Honey Formulation on Cell lines

Background: C. limon rich in Vitamin C was shown to have many health benefits having therapeutic properties. Honey was considered as an natural sweetener said to be immune booster. Hence the formulation of C. limon and honey formulation was studied to prevent oxidation and foam cell inhibition. Objectives: The present study was aimed to isolate tannins from Citrus limon ( C. limon ) fruit juice with a honey mixture to evaluate the antilipidemic and antioxidant activity in cell lines. Materials and Methods: Tannins were isolated from C. limon fruit juice with a honey mixture with two different solvents, i.e., methanol and water and analysed for antioxidant and LDL oxidation inhibition activity. Further tested on RAW 264.7 and THP-1 cells by employing in-vitro assays for cytotoxicity, foam cell development, inhibiting proliferation and, apoptosis. The tannin methanol extract was characterized using HPLC and GC-MS. Results: The content of total tannins present was found to be 453.96 mg tannic acid equivalent (TAE)/g methanol extract, whereas 415.87 mg TAE/g in tannin aqueous extract. The highest antilipidemic and antioxidant activity were seen in tannin methanol extract. It was seen that 240 μg/mL tannin methanol extract efficiently inhibited oxidation of low-density lipoproteins (55.89% at 5 hr), thus preventing foam cell development, inhibiting proliferation and, apoptosis in cultured RAW 264.7 and THP-1 cells. GCMS revealed certain compounds. Conclusion: This study showed that C. limon with honey tannin methanol extract exhibits potential for antiatherosclerosis activity henceforth, considering the medicinal properties of the active phytochemicals, which can be used as a source of naturally occurring nutraceuticals, revealed the potential to prevent oxidation and foam cell formation.
THE EFFECT OF MUDHARABAH AND MUSYARAKAH FINANCING ON THE PROFITABILITY OF ISLAMIC GENERAL BANKS FOR THE 2020-2021 PERIOD

Abstrak Penelitian ini bertujuan untuk mengetahui bagaimana pengaruh pembiayaan mudharabah dan musyarakah terhadap profitabilitas Bank Umum Syariah (BUS) selama periode 2020-2021. Penelitian ini menggunakan teknik analisis data deksriptif dengan metode pendekatan kuantitatif. Selain itu, teknik pengumpulan data yang digunakan adalah metode kepustakaan dan dokumentasi. Adapun hasil penelitian menunjukkan bahwa adanya pengaruh pembiayaan mudharabah dan musyarakah yang signifikan terhadap profitabilitas Bank Umum Syariah (BUS) selama periode 2020-2021. Kata Kunci: Pembiayaan Mudharabah, Pembiayaan Musyarakah, Profitabilitas Ekuitas Abstract The development of Islamic economics in Indonesia, especially in the Islamic banking industry, has experienced very rapid growth. This is evidenced by the increasing number of Islamic banking institutions. This is because Islamic banking puts forward the values of Islamic teachings so that it adheres to a profit-sharing system. The implementation of the profit-sharing system generally includes financing with the contracts: mudharabah and musyarakah. As an Islamic financial institution that also carries out economic activities, making a profit is something that cannot be avoided, especially regarding the sustainability of the institution. Because with the profit earned, investors can do business with the bank, especially in terms of equity participation with the provision of profit-sharing. This research aims to determine whether there is a significant effect of profit–sharing financings on the profitability of Islamic General Banks in Indonesia by a certain period, using descriptive analysis with a quantitative approach. The final result of this research shows that there was a significant and negative effect between mudharabah financing and the profitability of equity, on the other hand, there was a significant and positive effect between musyarakah financing and the profitability of equity. Keywords: Mudharabah Financing, Musyarakah Financing, Profitability of Equity
Consumers’ evaluation of imported 1 organic food products: The role of 2 geographical distance 3

The global organic food market has grown rapidly over the last decade (Sahota, 2018), passing 6 EUR 80 billion in 2016 (Willer & Lernoud, 2018). Germany is the world’s second largest market 7 for organic products and the largest in Europe, amounting to EUR 9.5 billion in 2016, about 30 8 percent of total European organic retail sales (Willer & Lernoud, 2018). Despite the organic 9 agricultural area being expanded and an increase in the number of organic producers (BÖLW, 1
Economic valuation and policy priorities for sustainable management of coral reefs

This publication is an outcome of the A´International Consultative Workshop for Economic Valuation and Policy Priorities for Sustainable Management of Coral ReefsA¶ held at the WorldFish Center's Headquarters in Penang, Malaysia, 8-10 December 2001.The overall goal of the workshop was to identify future directions for economic and policy research relevant to the sustainable management of coral reefs. The workshop was the final activity of the Valuation and Policy Analysis for Sustainable Management of Coral Reefs project. It was sponsored by the Center's donors and the Swedish International Development Cooperation Agency (Sida), with additional support from the International Coral Reef Action Network (ICRAN). The workshop also received support for selected participants from Southeast Asia from the Economy and Environment Program for Southeast Asia (EEPSEA) and the Australian Center for International Agricultural Research (ACIAR). A total of 48 participants from 15 countries located in Southeast and East Asia, the Caribbean, East Africa and the South Pacific Regional Seas contributed to the workshop.
Progress report:24 hour gridded population models

In a paper presented at the 2009 EFGS Conference in The Hague (Martin et al., 2009) we set out the early stages of a UK research project focused on the production of time-specific gridded population models. The present paper reviews overall progress with this work and develops in more detail some aspects of the modelling principles and available data sources which make this possible. The paper seeks to demonstrate how readily accessible data are beginning to provide many of the key inputs required to make time-specific representations of population. Time-specific models have the potential to overcome many key weaknesses of current representations which are generally based on dated population statistics about population numbers at place of residence and which fail to reflect massive cyclical spatial redistributions of population. In many application areas, current analyses persist in using population maps with major deficiencies due to the absence of plausible alternative models. The remainder of this paper is structured as follows: the following section provides a brief review of the case for more sophisticated time-space population distributions. The thirdsection reviews issues arising from the challenge of data source acquisition and integration and the final section indicates the progress made in the project to date with regard to addressing these challenges
A Neuroscientific Method for Assessing Effectiveness of Digital vs. Print Ads

ABSTRACT Marketers can choose among various media to convey advertising, ranging from printed advertising on paper to websites through the Internet and mobile through smartphones and tablets. Which medium is the most effective in terms of information memory or reading behavior is not clear, however. In this study, advertisements from an Italian newspaper were presented in three media formats: website (through the Internet with a desktop PC), paper, and a PDF version displayed on a tablet device. Responses to the same news and advertising were measured with eye tracker, electroencephalography (EEG) brain scanner, and memory test.
Physico-chemical and Phyto-chemical Standardization of a Potent Unani Cardiovascular drug Saad Kufi (Cyperus scariosus R. Br)

Background: Standardization of a single potent Unani drug Saad Kufi is a must for maintaining and assessing the quality and safety as to attain the desired therapeutic effect. This will help prepare the ideal monograph which will serve in establishing its authenticity, quality, safety and reproducibility. Aim: The study aims to prepare the ideal monograph of the Saad Kufi (Cyperus scariosus R.Br)which is an important cardiovascular drug. Methodology: Physicochemical and preliminary phytochemical analyses were carried out according to the guidelines given by WHO. Result: Saad Kufi powder was coarse, brown incolor, Agreeable smell, and Tasteless. Total ash, acid insoluble ash, water-soluble ash, loss in weight on drying, pH (1% and 10% solution) were found to be16.3±0.07, 8.616±0.20, 3.1±0.30, 8.5±0.173, 5.76±0.08 and 5.23±0.08 respectively. The crude fibre content was 46.43±0.19 The Phytochemical screening revealed the presence ofalkaloids, carbohydrates, proteins, phenols, sterols, glycosides, Cardiac glycosides, flavonoids, sterols/ terpenes and volatile oil. TLC studies of various extracts of drugs obtained in different solvent system have been conducted and Rf values of various spots in different solvent systems have been noted in day light, UV light and after treatment with iodine vapours. The Rf values in the given solvent are used to characterize the drugs identity and purity. Conclusion: The above findings could be considered for laying down pharmacopoeial standards. No data exhibits in this regard to compare with, thus our findings may be considered as standard for future references. Bangladesh Journal of Medical Science Vol. 21 No. 04 October’22 Page : 858-864
Robust Astronomical Imaging in the Presence of Radio Frequency Interference

Radio astronomical observations are increasingly contaminated by radio frequency interference (RFI), rendering the development of effective RFI suppression techniques a pressing task. In practice, the existence of model mismatch makes the observing environment more challenging. In this paper, we develop a robust astronomical imaging method in the presence of RFI and model mismatch. The key contribution of the proposed method is the accurate estimation of the actual signal steering vector by maximizing the beamformer output power subject to a constraint that prevents the estimated steering vector from converging to the interference steering vectors. The proposed method is formulated as a quadratically constrained quadratic programming problem that can be solved using efficient numerical approaches. Simulation results demonstrate the effectiveness of the proposed method.
A Metal-Oxide Thin-Film Transistor Technology With Donor-Species Drive-In Pretreatment

Accompanying a reduction in process temperature from 400 °C to 300 °C, the channel current of an elevated-metal metal-oxide (EMMO) thin-film transistor (TFT) is found to change from one insensitive to the size of the conductive source/drain (S/D) regions to one suppressed with decreasing size of the regions. The different behavior is attributed to the distinct donor-species responsible for the formation of the thermally induced S/D regions at the two process temperatures. Such sensitivity, often undesirable, can be reduced by completing a donor drive-in thermal treatment before the patterning of the S/D electrodes. This alternative process flow with drive-in pretreatment allows the construction at 300 °C of an EMMO TFT with a significantly reduced footprint while still exhibiting a relatively low S/D resistance.
Bruny on the Brink: Governance, Gentrification and Tourism on an Australian Island

This paper examines the influence of islandness on development and governance of Bruny Island (offshore from Tasmania, Australia’s only island state). While traditional economic activities, particularly agriculture, are in decline, tourism is increasingly important to the island economy. While some 600 people live on the island all-year-round; there are some 2,000 ratepayers, including holiday home owners. This location is being rapidly ‘discovered’ by people drawn from interstate and overseas to the island lifestyle, and this is leading to a process of gentrification, with consequences for islanders. Bruny Island’s local governing authority is based on the Tasmanian mainland and hence is another source of externally-driven change. Amidst these pressures, island community visioning can be an important source of resilience.
Stable anisotropic single-layer of ReTe$_2$: a first principles Stable anisotropic single-layer of ReTe$_2$: a first principles prediction prediction

: In order to investigate the structural, vibrational, electronic, and mechanical features of single-layer ReTe 2 first-principles calculations are performed. Dynamical stability analyses reveal that single-layer ReTe 2 crystallize in a distorted phase while its 1H and 1T phases are dynamically unstable. Raman spectrum calculations show that single-layer distorted phase of ReTe 2 exhibits 18 Raman peaks similar to those of ReS 2 and ReSe 2 . Electronically, single-layer ReTe 2 is shown to be an indirect gap semiconductor with a suitable band gap for optoelectronic applications. In addition, it is found that the formation of Re-units in the crystal induces anisotropic mechanical parameters. The in-plane stiffness and Poisson ratio are shown to be significantly dependent on the lattice orientation. Our findings indicate that single-layer form of ReTe 2 can only crystallize in a dynamically stable distorted phase formed by the Re-units. Single-layer of distorted ReTe 2 can be a potential in-plane anisotropic material for various nanotechnology applications.
HOW DID THE GLOBAL CRISIS AFFECT YOUTH UNEMPLOYMENT? A PANEL DATA ANALYSIS ON THE EUROPEAN REGION

The 2008 global crisis, that had a profound impact on production and labour markets all over the world, had its negative effects on the European countries to a great extent after the United States. These impacts were even more negative for young people, one of the weakest links in the labour market. The object of this study is to dissect the effects of the global crisis on youth unemployment in 32 European countries for the period of 2000-2018 using panel data estimation methods. The study can be seen as a precursor since the studies on the subject are scarce and the content of the study is comprehensive. The empirical analyses reveal that the youth unemployment rate in Europe has had a positive shift of about 3.75 percentage points after the global crisis. Growth rate, inflation rate and trade openness have negative relationship with youth unemployment. Lastly, the research unearths that when analyzed on the basis of gender, young men are more impressed by the crisis than young women in the region.
Running Header: BODY IMAGE ANOREXIA BULIMIA

35 Objective: This study examined the distinctiveness of specific constructs of body-image 36 disturbance in patients with anorexia nervosa (AN) and bulimia nervosa (BN). We compared 37 weight/shape dissatisfaction, weight/shape overvaluation, weight/shape preoccupation, and fear 38 of weight gain in patients with AN and BN and examined how each specific body-image 39 construct relates to clinical measures within and between AN and BN. Method: A clinical 40 sample of 490 treatment-seeking patients diagnosed with DSM-5 AN (N=310) or BN (N=180) by 41 clinicians using structured interviews in Portugal completed the Eating Disorder Examination-42 Questionnaire to assess body image and eating-disorder psychopathology. Results: Both within 43 and between AN and BN, the four body-image constructs varied in their strengths of association 44 amongst themselves, with eating-disorder psychopathology, and BMI. Analyses revealed 45 considerable variability in variance accounted for in clinical measures by body-image constructs. 46 Body-image constructs predicted significant, albeit small, variance in BMI within BN 47 (dissatisfaction, preoccupation significant) but not within AN. Body-image constructs predicted 48 significant, albeit small, variance in the frequencies of binge eating and purging in AN (with 49 preoccupation significant for both and fear for purging) but not within BN. Body-image 50 constructs predicted significant variance in eating-disorder psychopathology (large amounts of 51 variance for Eating Concern and Restraint) within both AN and BN (with overvaluation, 52 preoccupation, and fear significant). Conclusion: Clinical manifestations of body-image 53 disturbances are complex and show important differences across AN and BN. Understanding 54 distinctions and differential salience of different body-image constructs across different eating 55 disorders can inform refinement of specific case conceptualization. 56
Transcriptomic Analysis in the Hippocampus and Retina of Tg2576 AD Mice Reveals Defective Mitochondrial Oxidative Phosphorylation and Recovery by Tau 12A12mAb Treatment

Increasing evidence implicates decreased energy metabolism and mitochondrial dysfunctions among the earliest pathogenic events of Alzheimer’s disease (AD). However, the molecular mechanisms underlying bioenergetic dysfunctions in AD remain, to date, largely unknown. In this work, we analyzed transcriptomic changes occurring in the hippocampus and retina of a Tg2576 AD mouse model and wild-type controls, evaluating their functional implications by gene set enrichment analysis. The results revealed that oxidative phosphorylation and mitochondrial-related pathways are significantly down-regulated in both tissues of Tg2576 mice, supporting the role of these processes in the pathogenesis of AD. In addition, we also analyzed transcriptomic changes occurring in Tg2576 mice treated with the 12A12 monoclonal antibody that neutralizes an AD-relevant tau-derived neurotoxic peptide in vivo. Our analysis showed that the mitochondrial alterations observed in AD mice were significantly reverted by treatment with 12A12mAb, supporting bioenergetic pathways as key mediators of its in vivo neuroprotective and anti-amyloidogenic effects. This study provides, for the first time, a comprehensive characterization of molecular events underlying the disrupted mitochondrial bioenergetics in AD pathology, laying the foundation for the future development of diagnostic and therapeutic tools.
Radionuclide concentrations in terrestrial vegetation and soil on and around the Hanford Site, 1983 through 1993

This report reviews concentrations of {sup 60}Co, {sup 90}Sr, {sup 137}Cs, U isotopes, {sup 238}Pu, {sup 239,240}Pu, and {sup 241}Am in soil and vegetation samples collected from 1983 through 1993 during routine surveillance of the Hanford Site. Sampling locations were grouped in study areas associated with operational areas on the Site. While radionuclide concentrations were very low and representative of background concentrations from historic fallout, some study areas on the Site contained slightly elevated concentrations compared to other study areas onsite and offsite. The 100 Areas had concentrations of {sup 60}Co comparable to the minimum detectable concentration of 0.02 pCi/g in soil. Concentrations of {sup 90}Sr, {sup 137}Cs, {sup 238}Pu, {sup 239,240}Pu, and {sup 241}Am in 200 Area soils were slightly elevated. The 300 Area had a slight elevation of U in soil. These observations were expected because many of the sampling locations were selected to monitor specific facilities or operations at the operational areas. Generally, concentrations of the radionuclides studied were greater and more readily measured in soil samples compared to vegetation samples. The general pattern of concentrations of radionuclide concentrations in vegetation by area mirrored that observed in soil. Declines in {sup 90}Sr in soil appear to be attributed to radioactive decay and possibly downward migration out of the sampling horizon. The other radionuclides addressed in this report strongly sorb to soil and are readily retained in surface soil. Because of their long half-lives compared to the length of the study period, there was no significant indication that concentrations of U isotopes and Pu isotopes were decreasing over time.
QUALITATIVE RESEARCH The Use of Building Blocks to Teach Communication and Social Skills to First-year Pharmacy Students

Objective. To conduct an innovative workshop activity using plastic building blocks to create a student-centric environment that encouraged development of creative thinking skills and self-reflection in undergraduate pharmacy students. Methods. Students were randomly allocated into small groups of four and assigned the role of either architect or team builder and tasked with creating a LEGO robot. Students were not allowed to speak during the activity. The architect was tasked with providing instructions to team builders on how to build the robot using nonverbal communication. After completion of the task, each group was asked to reflect on the exercise and share what they learned with the entire class. These discussions were video recorded and thematically analyzed. Results. The metaphorical models that students built served as a basis for discussion, problem-solving, and decision-making. Students described how this activity enabled them to mentally and visually link abstract concepts, such as decision-making and problem-solving, to actual practice. Three themes were identified from the qualitative study: thinking with hands, listening with eyes; linking theory to practice; and learning through reflection. Conclusion. This activity offered a non-confrontational way to support communication and the learning process. The use of an interactive game can be a useful teaching strategy to create an active-learning environment, helping pharmacy students improve their social and cognitive skills, such as decision-making, problem-solving, and communication.
Six-Month Pulmonary Impairment after Severe COVID-19: A Prospective, Multicentre Follow-Up Study

Background: Long-term pulmonary sequelae following severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pneumonia are not yet confirmed; however, preliminary observations suggest a possible relevant clinical, functional, and radiological impairment. Objectives: The aim of this study was to identify and characterize pulmonary sequelae caused by SARS-CoV-2 pneumonia at 6-month follow-up. Methods: In this multicentre, prospective, observational cohort study, patients hospitalized for SARS-CoV-2 pneumonia and without prior diagnosis of structural lung diseases were stratified by maximum ventilatory support (“oxygen only,” “continuous positive airway pressure,” and “invasive mechanical ventilation”) and followed up at 6 months from discharge. Pulmonary function tests and diffusion capacity for carbon monoxide (DLCO), 6-min walking test, chest X-ray, physical examination, and modified Medical Research Council (mMRC) dyspnoea score were collected. Results: Between March and June 2020, 312 patients were enrolled (83, 27% women; median interquartile range age 61.1 [53.4, 69.3] years). The parameters that showed the highest rate of impairment were DLCO and chest X-ray, in 46% and 25% of patients, respectively. However, only a minority of patients reported dyspnoea (31%), defined as mMRC ≥1, or showed restrictive ventilatory defects (9%). In the logistic regression model, having asthma as a comorbidity was associated with DLCO impairment at follow-up, while prophylactic heparin administration during hospitalization appeared as a protective factor. The need for invasive ventilatory support during hospitalization was associated with chest imaging abnormalities. Conclusions: DLCO and radiological assessment appear to be the most sensitive tools to monitor patients with the coronavirus disease 2019 (COVID-19) during follow-up. Future studies with longer follow-up are warranted to better understand pulmonary sequelae.