Miracle-dz/UniFAR-FTUs huggingface dataset:
Improvement of the embedding efficiency of LSB matching by sum and difference covering set

As an important attribute directly influencing the steganographic scheme, the embedding efficiency is defined as the average number of random data bits per one embedding change. In this paper, we propose a novel approach to improve the embedding efficiency of LSB matching based on the sum and difference covering set (SDCS) of finite cyclic group. We show that the suitable choice of SDCS will lead to a new steganographic scheme which is more efficient than LSB matching. Then we illustrate that the new scheme keeps the statistical imperceptibility of LSB matching. The detailed constructions of SDCS are given and some related problems are also discussed.
Ovarian tissue cryopreservation for fertility preservation: clinical and research perspectives

Abstract BACKGROUND Small case series have reported successful live births after ovarian tissue cryopreservation and orthotopic transplantation, demonstrating that it can be of value in increasing the chance of successful pregnancy after treatment for cancer and other fertility-impacting diseases in adult women. OBJECTIVE AND RATIONALE This review is intended to set out the current clinical issues in the field of ovarian tissue cryopreservation, and elucidate the status of laboratory studies to address these. SEARCH METHODS We reviewed the English-language literature on ovarian tissue cryopreservation and in vitro maturation (IVM) of ovarian follicles. OUTCOMES Ovarian tissue cryopreservation is increasingly used for fertility preservation and, whilst areas for development remain (optimal patient selection, minimizing risk of contamination by malignant cells and IVM protocols), there are emerging data as to its efficacy. We review the current status of ovarian tissue cryopreservation in girls and young women facing loss of fertility from treatment of cancer and other serious diseases. Increasingly large cohort studies are reporting on success rates from ovarian tissue cryopreservation giving an indication of likely success rates. Patient selection is necessary to ensure the safety and effectiveness of this approach, especially in the very experimental situation of its application to prepubertal girls. There are continuing developments in supporting follicle development in vitro. LIMITATIONS, REASONS FOR CAUTION The evidence base consists largely of case series and cohort studies, thus there is the possibility of bias in key outcomes. In vitro development of human ovarian follicles remains some way from clinical application. WIDER IMPLICATIONS OF THE FINDINGS Ovarian tissue cryopreservation is becoming established as a valuable approach to the preservation of fertility in women. Its application in prepubertal girls may be of particular value, as it offers the only approach in this patient group. For both girls and young women, more accurate data are needed on the likelihood of successful childbirth after this procedure and the factors that underpin successful application of this approach, which will lead to its more effective use. STUDY FUNDING/COMPETING INTERESTS The author's work in this field is supported by Medical Research Grant (MRC) grants G0901839 and MR/L00299X/1 and partially undertaken in the MRC Centre for Reproductive Health which is funded by MRC Centre grant MR/N022556/1. The authors declare that there is no conflict of interest that could prejudice the impartiality of the present research.
phot1 Inhibition of ABCB19 Primes Lateral Auxin Fluxes in the Shoot Apex Required For Phototropism

It is well accepted that lateral redistribution of the phytohormone auxin underlies the bending of plant organs towards light. In monocots, photoreception occurs at the shoot tip above the region of differential growth. Despite more than a century of research, it is still unresolved how light regulates auxin distribution and where this occurs in dicots. Here, we establish a system in Arabidopsis thaliana to study hypocotyl phototropism in the absence of developmental events associated with seedling photomorphogenesis. We show that auxin redistribution to the epidermal sites of action occurs at and above the hypocotyl apex, not at the elongation zone. Within this region, we identify the auxin efflux transporter ATP-BINDING CASSETTE B19 (ABCB19) as a substrate target for the photoreceptor kinase PHOTOTROPIN 1 (phot1). Heterologous expression and physiological analyses indicate that phosphorylation of ABCB19 by phot1 inhibits its efflux activity, thereby increasing auxin levels in and above the hypocotyl apex to halt vertical growth and prime lateral fluxes that are subsequently channeled to the elongation zone by PIN-FORMED 3 (PIN3). Together, these results provide new insights into the roles of ABCB19 and PIN3 in establishing phototropic curvatures and demonstrate that the proximity of light perception and differential phototropic growth is conserved in angiosperms.
Parametric Weight Comparison of Advanced Metallic, Ceramic Tile, and Ceramic Blanket Thermal Protect

A parametric weight assessment of advanced metallic panel, ceramic blanket, and ceramic tile thermal protection systems (TPS) was conducted using an implicit, one-dimensional (1-D) finite element sizing code. This sizing code contained models to account for coatings, fasteners, adhesives, and strain isolation pads. Atmospheric entry heating profiles for two vehicles, the Access to Space (ATS) vehicle and a proposed Reusable Launch Vehicle (RLV), were used to ensure that the trends were not unique to a certain trajectory. Ten TPS concepts were compared for a range of applied heat loads and substructural heat capacities to identify general trends. This study found the blanket TPS concepts have the lightest weights over the majority of their applicable ranges, and current technology ceramic tiles and metallic TPS concepts have similar weights. A proposed, state-of-the-art metallic system which uses a higher temperature alloy and efficient multilayer insulation was predicted to be significantly lighter than the ceramic tile systems and approaches blanket TPS weights for higher integrated heat loads.
Use of NMR in fish processing optimization: a review of recent progress

The goal of this review is to give an overview of general trends in the application of the NMR related to fish processing and quality and to provide some viewpoints on the current situation. Three novel examples of the application of the methodologies magnetic resonance spectroscopy, magnetic resonance imaging, and low‐field NMR are also presented. The capability of these techniques to be utilized as a tool to optimize fish processing, and thereby improving product quality, as well as to confirm labelling information, are demonstrated. Copyright © 2012 John Wiley & Sons, Ltd.
A new variable step size INC MPPT method for PV systems

Maximum power points tracking (MPPT) techniques are widely utilized in photovoltaic (PV) systems to operate at the peak power of PV array which depends on solar and ambient temperature. Between all the MPPT strategies, the incremental conductance (INC) algorithm is extensively employed due to the high tracking accuracy at steady state and good adaptability to the rapidly changing atmospheric conditions. In this paper, a novel variable step-size incremental conductance MPPT algorithm is used in solar array power systems with direct control method, which automatically adjusts the step size to track MPP without the proportional-integral control loop. Compared with conventional INC and variable step-size INC method, the proposed method can largely improve the MPPT response speed and accuracy at steady state simultaneously without steady-state oscillation. The proposed algorithm was tested in MATLAB/SIMULINK environment. Results show the feasibility, a faster response speed and higher tracking accuracy in changing irradiance.
How acute and reversible are the cardiovascular risks of secondhand smoke?

Could eating in a smoky restaurant precipitate an acute myocardial infarction in a non—smoker? As unlikely as this sounds, a growing body of scientific data suggests that this is possible. In this context, the results of the observational study in Helena, MT are provocative: hospital admissions for acute myocardial infarction declined by about 40% during the six months in which a comprehensive local ordinance on clean air was in effect, and rebounded after the ordinance was suspended.1 Given the small size and observational design of the study, these findings might be discounted or even disregarded altogether. However, the study focuses attention on an interesting subset of literature on secondhand smoke and its consequences. We now have a considerable amount of epidemiological literature and laboratory data on the mechanisms by which relatively small exposures to toxins in tobacco smoke seem to cause unexpectedly large increases in the risk of acute cardiovascular disease.2–7 Exposure to secondhand smoke increases the risk of fatal and non-fatal coronary heart disease in non-smokers by about 30%. 2 5 8 9 Because coronary heart disease is a leading cause of death in many countries, even relatively small increases in risk from this one factor can result in a large population burden of disease attributable to exposure to tobacco smoke.10 11 While the substantial cardiovascular risks posed by active smoking are now almost universally accepted, the tobacco industry and some other observers continue to question the idea that secondhand smoke can cause cardiovascular disease and death.12–15 Notwithstanding the substantial clinical and experimental evidence regarding the adverse cardiovascular effects of exposure to secondhand smoke, some have argued that an association between low level environmental exposures and health outcomes should be more critically evaluated, particularly when the relative risk for the exposure …
Formation of the shoot apical meristem in Arabidopsis thaliana: an analysis of development in the wild type and in the shoot meristemless mutant

The primary shoot apical meristem of Arabidopsis is initiated late in embryogenesis, after the initiation of the cotyledons. We have identified a gene, called SHOOT MERISTEMLESS, which is critical for this process. shoot meristemless mutant seedlings lack a shoot apical meristem but are otherwise healthy and viable. The anatomy of mutant embryos demonstrates that the shoot meristemless-1 mutation completely blocks the initiation of the shoot apical meristem, but has no other obvious effects on embryo development. The failure of shoot meristemless tissue to regenerate shoots in tissue culture suggests that this gene regulates adventitious shoot meristem formation, as well as embryonic shoot meristem formation.
The combinatorics of LCD codes: linear programming bound and orthogonal matrices

Linear Complementary Dual codes (LCD) are binary linear codes that meet their dual trivially. We construct LCD codes using orthogonal matrices, self-dual codes, combinatorial designs and Gray map from codes over the family of rings $R_k$. We give a linear programming bound on the largest size of an LCD code of given length and minimum distance. We make a table of lower bounds for this combinatorial function for modest values of the parameters.
Pattern Representation in Feature Extraction and Classifier Design: Matrix Versus Vector

The matrix, as an extended pattern representation to the vector, has proven to be effective in feature extraction. However, the subsequent classifier following the matrix-pattern-oriented feature extraction is generally still based on the vector pattern representation (namely, MatFE + VecCD), where it has been demonstrated that the effectiveness in classification just attributes to the matrix representation in feature extraction. This paper looks at the possibility of applying the matrix pattern representation to both feature extraction and classifier design. To this end, we propose a so-called fully matrixized approach, i.e., the matrix-pattern-oriented feature extraction followed by the matrix-pattern-oriented classifier design (MatFE + MatCD). To more comprehensively validate MatFE + MatCD, we further consider all the possible combinations of feature extraction (FE) and classifier design (CD) on the basis of patterns represented by matrix and vector respectively, i.e., MatFE + MatCD, MatFE + VecCD, just the matrix-pattern-oriented classifier design (MatCD), the vector-pattern-oriented feature extraction followed by the matrix-pattern-oriented classifier design (VecFE + MatCD), the vector-pattern-oriented feature extraction followed by the vector-pattern-oriented classifier design (VecFE + VecCD) and just the vector-pattern-oriented classifier design (VecCD). The experiments on the combinations have shown the following: 1) the designed fully matrixized approach (MatFE + MatCD) has an effective and efficient performance on those patterns with the prior structural knowledge such as images; and 2) the matrix gives us an alternative feasible pattern representation in feature extraction and classifier designs, and meanwhile provides a necessary validation for "ugly duckling" and "no free lunch" theorems.
Persistent, Long-term Cerebral White Matter Changes after Sports-Related Repetitive Head Impacts

Introduction Repetitive head impacts (RHI) sustained in contact sports are thought to be necessary for the long-term development of chronic traumatic encephalopathy (CTE). Our objectives were to: 1) characterize the magnitude and persistence of RHI-induced white matter (WM) changes; 2) determine their relationship to kinematic measures of RHI; and 3) explore their clinical relevance. Methods Prospective, observational study of 10 Division III college football players and 5 non-athlete controls during the 2011-12 season. All subjects underwent diffusion tensor imaging (DTI), physiologic, cognitive, and balance testing at pre-season (Time 1), post-season (Time 2), and after 6-months of no-contact rest (Time 3). Head impact measures were recorded using helmet-mounted accelerometers. The percentage of whole-brain WM voxels with significant changes in fractional anisotropy (FA) and mean diffusivity (MD) from Time 1 to 2, and Time 1 to 3 was determined for each subject and correlated to head impacts and clinical measures. Results Total head impacts for the season ranged from 431–1,850. No athlete suffered a clinically evident concussion. Compared to controls, athletes experienced greater changes in FA and MD from Time 1 to 2 as well as Time 1 to 3; most differences at Time 2 persisted to Time 3. Among athletes, the percentage of voxels with decreased FA from Time 1 to 2 was positively correlated with several helmet impact measures. The persistence of WM changes from Time 1 to 3 was also associated with changes in serum ApoA1 and S100B autoantibodies. WM changes were not consistently associated with cognition or balance. Conclusions A single football season of RHIs without clinically-evident concussion resulted in WM changes that correlated with multiple helmet impact measures and persisted following 6 months of no-contact rest. This lack of WM recovery could potentially contribute to cumulative WM changes with subsequent RHI exposures.
The side effects of gassing in transmission power transformers

The Dissolved Gas Analysis (DGA) of insulating oils has, over the last few decades, become a widely used technique for detecting and diagnosing incipient electrical failures inside the windings of power transformers. Since the decomposition of oil indicates a threat to the operational safety of these expensive machines, electrical engineers focus their attention on the amount and nature of the gases evolved. Based upon the relationship that was established between the results of DGA and the potential cause of such deficiencies, appropriate preventive measures are taken to protect the transformer. However, the side effects of a hydrocarbon chain breakdown on the insulating properties of oil are generally not taken into consideration. When a hydrogen atom is knocked out from a hydrocarbon it means that the two electrons of a covalent bond were homolytically separated. While the hydrogen content of oil and other low molecular weight gases is carefully monitored, the decay products generated by the chemically reactive large fragments of decomposed molecules are ignored. Significant technological progress has been made in the laboratory analysis of oil, which offers the opportunity to reveal the link between gassing and the deterioration of liquid insulation quality under service conditions. This paper describes the unavoidable implications of secondary chemical reactions, caused by the gas evolvement of oil subjected to thermal and electrical stress.
An error control scheme for large-scale multicast applications

Retransmission based error control for large scale multicast applications is difficult because of implosion and exposure. Existing schemes (SRM, RMTP, TMTP LBRRM) have good solutions to implosion, but only approximate solutions to exposure. We present a scheme that achieves finer grain fault recovery by exploiting new forwarding services that allow us to create a dynamic hierarchy of receivers. We extend the IP multicast service model so that routers provide a more refined form of multicasting (which may be useful to other applications), that enables local recovery. The new services are simple to implement and do not require routers to examine or store application packets; hence, they do not violate layering. Besides providing better implosion control and less exposure than other schemes, our scheme integrates well with the current IP model, has small recovery latencies (it requires no back-off delays), and completely isolates group members from topology. Our scheme can be used with a variety of multicast routing protocols, including DVMRP and PIM. We have implemented our scheme in NetBSD Unix, using about 250 lines of new C-code. The implementation requires two new IP options, 4 additional bytes in each routing entry and a slight modification to IGMP reports. The forwarding overhead incurred by the new services is actually lower than forwarding normal multicast traffic.
Effects of maternal hypertension in very-low-birth-weight infants.

OBJECTIVE To determine the effects of mild vs severe maternal hypertension on the neonatal morbidity of very-low-birth-weight infants. DESIGN Cohort case-control study. SETTING Tertiary care center neonatal intensive care unit. PATIENTS Thirty-nine infants born to mothers with maternal hypertension (blood pressure > or = 140/90 mm Hg on 2 occasions during pregnancy) among 267 very-low-birth-weight infants (< or = 1250 g) admitted to the special care nursery between January 1, 1991, and December 31, 1992. Each infant was matched for gestational age and survival to 2 control infants born to normotensive mothers. The cohort included 11 infants of mothers with mild hypertension, 28 with severe hypertension, and 78 controls. MAIN OUTCOME MEASURES Late and variable decelerations, incidence of small size for gestational age, respiratory distress syndrome, intraventricular hemorrhage, patent ductus arteriosus, apnea, ventilator therapy, oxygen requirement, and bronchopulmonary dysplasia. RESULTS The mild and severe maternal hypertension groups had significantly lower birth weights and more infants small for gestational age than did controls. The incidence of respiratory distress syndrome, however, was significantly lower in infants of mothers with mild hypertension than in those with mothers with severe hypertension. Those in the mild group had fever days of ventilatory therapy and lower oxygen requirements than both the infants in the severe group and control infants. The incidence of apnea in the mild hypertension group was significantly lower than that in the severe hypertension group. CONCLUSIONS Although mothers with both mild and severe hypertension have an increased incidence of infants small for gestational age, the infants born to mothers with mild hypertension had less respiratory distress syndrome, apnea, ventilator therapy, oxygen requirements, and bronchopulmonary dysplasia when compared with very-low-birth-weight infants born to mothers with severe hypertension.
Production of Chitosan-Based Non-Woven Membranes Using the Electrospinning Process

Chitosan is a modified natural polymer mainly produced from chitin, one of the most abundant organic materials in the world. Highly porous chitosan mats present the specific physicochemical properties of the base material and also benefit from the physical characteristics of nanoporous membranes. Electrospinning is a novel technique developed long time ago and revisited recently that can generate polymeric fibers with nanometric size. The ultimate purpose of this work is to fabricate microporous non-woven chitosan membranes for wound healing dressings and heavy metal ion removal from drinking water. In this dissertation, two approaches have been utilized to prepare chitosan-based nanofibers; blending and co-axial electrospinning of chitosan solution with a readily electrospinnable solution, i.e. an aqueous solution of polyethylene oxide (PEO). Consequently, understanding the phase behavior and miscibility of aqueous acidic solutions of chitosan and PEO and their blends is of crucial importance, as any phase separation occurring during the electrospinning process greatly changes the morphology and physico-mechanical properties of the final products. First we employed the rheological approach on a well-known aqueous PEO solution to develop the experimental protocol. By comparing these critical points with that obtained from other experimental techniques, we showed that rheological measurements can sensitively detect early stages of phase separation. Subsequently the method was applied to 50 wt% aqueous acetic acid solutions of PEO, chitosan and their blends at different ratios. These solutions showed a lower critical solution temperature (LCST) phase diagram that is attributed to the existence of hydrogen bonds between active groups on chitosan and PEO backbone and the solvent. Critical decomposition temperatures for binodal and spinodal points were estimated from isochronal temperature sweep experiments. The obtained binodal temperatures confirmed that chitosan/PEO solutions are miscible and stable at moderate temperatures and phase separate at higher temperatures of 60-75 °C. Then, we intended to obtain a thorough understanding of chitosan/PEO solution properties that lead to a successful electrospinning process, i.e. continuous and stable, and which produces defect free uniform beadless nanofibers. The effect of blend composition and acetic acid
A Low-Power and High-Precision Spread Spectrum Clock Generator for Serial Advanced Technology Attachment Applications Using Two-Point Modulation

A new technique utilizing two-point (TP) modulation for a spread spectrum clock generator (SSCG) for serial advanced technology attachment is presented in which the divider ratio is varied by a digital SigmaDelta modulator, and the voltage-controlled oscillator is modulated analogically. With this technique, the modulation bandwidth is enhanced in order that the modulation profile accuracy and jitter performance caused by the SigmaDelta modulator can be improved at the same time. The order of the SigmaDelta modulator and the loop filter can be reduced to save power and area, while the electromagnetic interference (EMI) suppression still satisfies specifications. The dual-path loop filter (DL) reduces the size of the loop capacitor and enables full integration. The proposed TPDL-SSCG has been fabricated in a 0.18 mum CMOS process. The size of the chip area is 0.44 times 0.48 mm2. The circuit produces a clock of 1.5 GHz with a down-modulation ratio of 0.5%, 10.14 dB EMI of reduction, 5.485 ps rms jitter, and 35 ps peak-to-peak jitter. The power consumption, excluding an output buffer, is only 15.3 mW.