Miracle-dz/UniFAR-FTUs huggingface dataset:
How an Immune-Factor-Based Formulation of Micro-Immunotherapy Could Interfere with the Physiological Processes Involved in the Atopic March

Allergic diseases consist of improper inflammatory reactions to antigens and are currently an important healthcare concern, especially considering their increasing worldwide development in recent decades. The “atopic march” defines the paradigm of allergic diseases occurring in chronological order and displaying specific spatial manifestations, as they usually start as atopic dermatitis (AD) and food allergies during infancy and progressively evolve into allergic asthma (AA) and allergic rhinitis (AR) or rhino-conjunctivitis in childhood. Many immune cell subtypes and inflammatory factors are involved in these hypersensitivity reactions. In particular, the T helpers 2 (Th2) subset, through its cytokine signatures made of interleukins (ILs), such as IL-4, IL-5, IL-10, and IL-13, as well as mast cells and their related histamine pathways, contribute greatly to the perpetuation and evolution of the atopic march. By providing low doses (LD) and ultra-low doses (ULD) of ILs and immune factors to the body, micro-immunotherapy (MI) constitutes an interesting therapeutic strategy for the management of the atopic march and its symptoms. One of the aims of this review is to shed light on the current concept of the atopic march and the underlying immune reactions occurring during the IgE-mediated responses. Moreover, the different classes of traditional and innovative treatments employed in allergic diseases will also be discussed, with a special emphasis on the potential benefits of the MI medicine 2LALERG® formulation in this context.
Parallel superposition in entangled polydisperse polymer melts: Experiments and theory

Parallel superposition experiments are used here for the linear and nonlinear rheological characterization of a commercial polydisperse polymer melt in the entangled state. In the limit of small amplitude of the oscillations, we focus (to our knowledge for the first time) on the time-temperature superposition principle. With increasing oscillation amplitudes, the storage and loss moduli become amplitude-dependent at amplitudes which vary with the strength of the background flow. Experimental results are compared with predictions of a recent molecularly-based constitutive equation in order to validate the equation itself as well as to interpret the data in terms of the molecular mechanisms accounted for in the constitutive equation.
Measurement and predictions of hearing handicap using an additive noise model.

The ability to accurately, quickly, and reliably measure speech intelligibility in noise is an essential requirement for assessing the benefit of hearing aids to speech communication in noisy environments. Measurement error caused by variability of speech materials, content, speaking styles, talkers, and spectral characteristics of noise maskers often make accurate intelligibility measurements impractical. This paper will review measurements of speech intelligibility as applied to the hearing impaired. Emphasis will be placed on Dutch sentence tests developed by Plomp [e.g., R. Plomp, J. Acoust. Soc. Am. 63, 533–549 (1978)] and on recent English sentence tests we have developed, which control many of the sources of measurement error. Test development procedures will be described, and a summary of initial results will be used to demonstrate the reliability of the tests for both group and individual assessment of intelligibility in noise.
Examination of the Relationship Between Breastfeeding Self-Efficacy and Perceived Breastfeeding Sufficiency of Mothers

BACKGROUND/AIMS: This study aimed to investigate the relationship between breastfeeding self-efficacy and perceived breastfeeding sufficiency of mothers with healthy infants aged 0-6 months who applied to the pediatric outpatient clinic of a public hospital and a university hospital in the Turkish Republic of North Cyprus. MATERIAL and METHODS: This was a descriptive and correlational study. The universe of this study consisted of mothers who had 0-6 months old infants who applied to the pediatric outpatient clinic of a public hospital and the gynecology service of a university hospital. The data of this study were collected by using a questionnaire form containing the mothers’ descriptive information, the Breastfeeding Self-efficacy Scale and the Perceived Insufficient Milk Questionnaire. RESULTS: When the mothers’ mean scores on the Breastfeeding Self-Efficacy Scale and the Perceived Insufficient Milk Questionnaire were evaluated, it was found that the mean score on the Breastfeeding Self-Efficacy Scale was X:60.16 ± standard deviation (SD) =9.00 and the mean score on the Perceived Insufficient Milk Questionnaire was X:42.06 ± SD =8.26. A statistically significant positive correlation was found between the scores on these two scales (r=0.66, p=0.00). Those mothers who were 25 years old or younger and those mothers who were 36 years old or older were found to have 19 higher perceptions of breastfeeding self-efficacy than the mothers in the other age groups (p<0.05). CONCLUSION: In this study, the mothers’ status of giving complementary foods affected their perceived milk insufficiency. This study found that breastfeeding self-efficacy increased when the perception of milk adequacy increased.
Scattering of High‐Frequency Sound Waves in Polycrystalline Materials

The calculations of a previous paper, which were based on a simplification in that the effective elastic properties of each grain were described by just Lame's two elastic constants, are generalized to take into account the fact that an elastically anisotropic medium has actually several independent elastic constants. The final expressions for the attenuation coefficient of shear and dilatational waves exhibit qualitatively similar features as the corresponding expressions of the previous paper but differ quantitatively from them.
Applying Cauchy‐Born rule for converting atomistic model to continuum model

The Cauchy‐Born rule has been applied in the Quasicontinuum method to derive continuum material properties based on underlying atomistic model in a physically consistent way. In this short work, the procedure is demonstrated, where the resulted materials constants are compared with experimental data found in literature. Moreover, the condition for applying the Cauchy‐Born rule is discussed, with an intuitive explanation for why it can be only applied to crystalline materials with perfect structure. (© 2010 Wiley‐VCH Verlag GmbH & Co. KGaA, Weinheim)
Inhomogeneous diophantine approximation for generic homogeneous functions

The present paper is a sequel to [Monatsh. ~Math.\ {\bf 194} (2021), 523--554] in which results of that paper are generalized so that they hold in the setting of inhomogeneous Diophantine approximation. Given any integers $n \geq 2$ and $\ell \geq 1$, any ${\pmb \xi} = \left(\xi_1, \dots , \xi_\ell \right) \in \mathbb{R}^\ell$, and any homogeneous function \linebreak $f = \left(f_1, \dots , f_\ell \right): \mathbb{R}^n \to \mathbb{R}^\ell$ that satisfies a certain nonsingularity assumption, we obtain a biconditional criterion on the approximating function $\psi = \left(\psi_1, \dots , \psi_\ell \right): \mathbb{R}_{\geq 0} \to \left(\mathbb{R}_{>0}\right)^\ell$ for a generic element $f \circ g$ in the $\operatorname{SL}_n(\mathbb{R})$-orbit of $f$ to be (respectively, not to be) $\psi$-approximable at ${\pmb \xi} = (\xi_1,\dots,\xi_n)$: that is, for there to exist infinitely many (respectively, only finitely many) $\mathbf{v} \in \mathbb{Z}^n$ such that $\left|\xi_j - \left( f_j \circ g\right)(\mathbf{v})\right| \leq \psi_j(\|\mathbf{v}\|)$ for each $j \in \left\lbrace 1, \dots, \ell \right\rbrace$. In this setting, we also obtain a sufficient condition for uniform approximation. We also consider some examples of $f$ that do not satisfy our nonsingularity assumptions and prove similar results for these examples. Moreover, one can replace $\operatorname{SL}_n(\mathbb{R})$ above by any closed subgroup of $\operatorname{ASL}_n(\mathbb{R})$ that satisfies certain integrability axioms (being of Siegel and Rogers type) introduced by the authors in the aforementioned previous paper.
Investigation of cone-beam acquisitions implemented using a novel dedicated mammotomography system with unique arbitrary orbit capability (Honorable Mention Poster Award)

We investigate cone-beam acquisitions implemented on a novel dedicated cone-beam transmission computed mammotomography (CmT) system with unique arbitrary orbit capability for pendant, uncompressed breasts. We use a previously reported optimized quasi-monochromatic beam technique together with orbits made possible with a novel CmT gantry system, to evaluate Vertical-Axis-Of-Rotation (VAOR), Circle-Plus-Two-Arcs (CP2A), and Saddle trajectories. Aquisition parameters include: W target, 60 kVp tube potential, 100th VL Nd filtration, 1.25 mAs, 55 cm SID, CsI(Tl) digital flat panel x-ray detector, and 7.7cm diameter uniform disc (Defrise) and resolution phantoms. Complex orbits were also performed for a realistic breast phantom. Reconstructions used an iterative ordered subsets transmission (OSTR) algorithm with 4x4 binned projections, 8 subsets, and 10 iterations, with 0.125 mm3 voxels. We evaluate the results for image artifacts, distortion, and resolution. Reconstructed images of the disc coronal and sagittal slices show significant distortion of the discs and phantom interfaces away from the central plane of the cone-beam for VAOR, less distortion for CP2A, and minimal distortion for the complex 3D Saddle orbit. Resolution phantoms indicate no loss of resolution with the Saddle orbit, with the smallest 1.1mm diameter rods clearly resolved. Other image artifacts such as streaking were also significantly reduced in the Saddle orbit case. Results indicate that arbitrary orbits of pendant uncompressed breasts using cone-beam acquisitions and OSTR iterative reconstructions can be successfully implemented for dedicated CmT to improve angular sampling with significant reduction in distortion and other image artifacts. This capability has the potential to improve the performance of dedicated CmT by adequately sampling the breast and anterior chest volumes of prone patients with pendant, uncompressed breasts.
An Additive On-Line Portfolio Selection Algorithm

An on-line portfolio management algorithm using additive update rule is presented with consideration of proportional transaction costs. After establishing a relationship between transaction costs and the distance of two portfolio vectors, we solve an optimization problem making a balance between high wealth growth rate and low transaction costs. It is shown that the presented portfolio strategy is universal relative to the set of all buy-and-hold portfolios in the sense that it achieves the same asymptotic exponential growth rate of wealth as the best buy-and-hold portfolio determined with hindsight. The simulation examples using the real data from the London Stock Exchange show the efficiency and the computational simplicity of the algorithm.
Ground state of the electron in the magnetic field of a straight current

The Pauli Hamiltonian for the electron moving in the magnetic field of a straight current with an axially symmetric distribution of current density possesses N = 3 broken supersymmetry. We study the ground state energy for the electron moving in this field. The asymptotic behaviour of ground state energy for small total angular momentum is obtained.
Thrust Efficiency Calculation for Magnetic Nozzle in Laser Fusion Rocket

Analysis of plasma behavior in a magnetic nozzle would be very useful for designing plasma propulsion systems such as inertial confinement fusion rockets and laser thermal propulsion. A magnetic nozzle would achieve a high exhaust velocity (high propellant utilization efficiency), because plasma would not contact wall structures directly when exhausted from the nozzle. Some conceptual designs for a laser fusion rocket (LFR) have been proposed. The rocket has a magnetic nozzle and controls the plasma flow resulting from laser fusion by using a superconducting magnetic (SCM) coil, obtaining thrust by exhausting the plasma flow from the back of the rocket. Hyde designed an LFR and proposed a magnetic nozzle using two SCM coils. He then proposed a new design and estimated its thrust efficiency using two-dimensional (2D) magnetrohydrodynamics (MHD) code for one coil system; the thrust efficiency was reported to be 65%. Nagamine and Nakashima calculated plasma behaviors and thrust efficiency using three-dimensional (3D) hybrid code for a magnetic nozzle using one coil, and examined how the thrust efficiency varies with certain parameters. Since these efficiency estimates were performed for magnetic nozzles using one coil, we investigated plasma behaviors and thrust efficiency for a model with two coils by using the 3D hybrid code, and conducted optimization of thrust efficiency for the magnetic nozzle. Thrust efficiency is defined as follows in terms of momentum :
Exploring the Determinants of Polypharmacy Prescribing and Dispensing Behaviors in Primary Care for the Elderly—Qualitative Study

Polypharmacy is particularly prevalent in the elderly. The interest in this issue is growing, and many interventions exist to improve the appropriate use of polypharmacy for older people. However, evidence of their effectiveness is still limited. Thus, the aim of this study, based on a qualitative approach, was to identify the key elements perceived to influence the prescribing and dispensing of appropriate polypharmacy to older people in primary care. Semistructured interviews were conducted with general practitioners and community pharmacists practicing in the region of Nouvelle-Aquitaine (France). Pre-existing topic guides based on the 12 TDF domains have been adapted and used. Data were analyzed using the framework method and content analysis. A focus group of healthcare professionals was conducted, and behavior change techniques (BCTs) were used to select the intervention components. Seventeen interviews were convened. A wide range of determinants were identified as barriers and/or facilitators. Nine domains were selected as key domains to target for intervention. Five intervention components (behavior change techniques—BCTs) to include in an intervention were finally selected. The results of this study will serve as a starting point for the design of a theory-based intervention targeting healthcare professionals to improve appropriate prescribing and dispensing of polypharmacy for older people in primary care.
Porous silicon optical sensors for vapors, liquids, and biological molecules

Recently, an increasing interest has been devoted to the use of porous silicon (p-Si) in photonics and in sensing fields. In particular, the great reactivity, mainly due to its large surface to volume ratio, has demonstrated to be promising in sensing applications for the detection of gases, vapors, and biochemical molecules. In this work, we present experimental and numerical results on p-Si optical microcavities as sensing transducers in biological and chemical fields. The measures are based on the change of the cavity reflectivity spectrum induced by the exposition to the bio-chemical specimen under test. The p-Si microcavity has a Fabry-Pèrot structure confined between two Distributed Bragg Reflectors (DBRs) with high reflectivity in the wavelength range of interest. The DBRs have been obtained modulating the porosity, therefore the refractive index, of p-Si layers during the silicon electro-chemical etching process. The optical thickness (nd) of each single-layer forming the DBR is l/4, where d is the layer physical thickness, n its refractive index and l is the Bragg wavelength. A l/2-thick layer placed between the top and bottom DBRs works as a microcavity resonating at the Bragg wavelength l. The realized sensors operate at the fiber optic communication wavelength of 1.55 mm. A complete experimental characterization of the devices as vapor and liquid sensor is reported. An analytical model, allowing the correct interpretation of the sensing dynamics, is also reported and discussed. Finally, preliminary results concerning DNA-probe immobilization in p-Si pores and consequent recognition of complementary DNA strands are presented.
Value Chain and the Integrated Development of Manufacturing and Modernized Services: A Case Study of Shandong Province, China

The integrated development of manufacturing and modernized service (IDMMS) is an important direction for the transformation and upgrading of manufacturing. Building upon value co-creation, industry chain theory and the industrial boundary literature, this paper explores an analytical framework of IDMMS, combining theoretical and empirical evidence. Then, this study constructs several indicators for measurement of industrial integration. The results indicate that: (1) manufacturing has more self-circulation, and the degree of backward correlation between the modernized services and the manufacturing is weak, while the support and driving effect of the manufacturing is insufficient; (2) most industrial sectors play a relatively stable role in influencing production demand. The findings reveal that there exist several problems referring to industry and enterprises. Finally, this paper discusses the mechanism of IDMMS and reaches its conclusions. The conclusions provide a comprehensive and detailed industrial understanding of the formation of comprehensive and systematic regional economic strategies and suggest targeted industrial policies to achieve sustainable development.
A laser Doppler velocimeter for surface velocity measurement

The velocimeter described is intended for measuring given lengths of iron wire in a rolling mill. The device is based on the conventional local oscillator heterodyne mode. To prevent the disappearance of the Doppler signal caused by movements of the wire in a direction perpendicular to the wire and laser beam, a broadening of the beam by means of a cylindrical lens is also proposed. The maximum Doppler frequency of the system is about 50 MHz, and the corresponding surface velocity is 66 m s-1 at a measurement angle of 14 degrees .
Testing the Equality of Two Related Intraclass Reliability Coefficients

An approximate statistical test of the equality of two intraclass reliability coefficients based on the same sample of people is derived. Such a test is needed when a researcher wishes to compare the reliability of two measurement procedures and both procedures can be applied to the performances or products of the same group of individuals. A numerical example is presented. Monte carlo studies indicate that the proposed test effectively controls Type I error with as few as two or three measurements on each of 50 people. Index terms: equality of related intraclass reliability coefficients, intraclass reliability, sampling theory, Speannan-Brown extrapolation, statistical test.
“The Uniform’s in the Way”: Navigating the Tension Between Security and Therapeutic Roles in a Rehabilitation-Focused Prison in Norway

The Norwegian Correctional Service ascribes to both a humane and rehabilitative approach to incarceration which includes the use of dynamic security practices, emphasizing relationship-building and communication between officers and incarcerated individuals. In addition, officers are expected to actively participate in the rehabilitative process. Despite Norway’s low rates of prison-based violence, there remain questions about officers’ ability to implement dynamic security and contribute to therapeutic goals. The current study explores perspectives about dynamic security and officer relationships using a questionnaire (n = 81) and semi-structured interview (n = 47) data from individuals incarcerated at Halden Prison in Norway. Findings indicate that officers have generally attained authoritative legitimacy through dynamic security, but their participation in the rehabilitative process is met with resistance stemming from prison culture expectations of officers’ role in enacting State punishment. Results from this study provide meaningful insights into the role of dynamic security implementation and the contributions of correctional officers to the rehabilitative process.
Incomplete markets: convergence of options values under the minimal martingale measure

In the setting of incomplete markets, this paper presents a general result of convergence for derivative assets prices. It is proved that the minimal martingale measure first introduced by Föllmer and Schweizer is a convenient tool for the stability under convergence. This extends previous well-known results when the markets are complete both in discrete time and continuous time. Taking into account the structure of stock prices, a mild assumption is made. It implies the joint convergence of the sequences of stock prices and of the Radon-Nikodym derivative of the minimal measure. The convergence of the derivatives prices follows. This property is illustrated in the main classes of financial market models.
Magnetically driven assembly of superparamagnetic colloidal particles

Thin ferromagnetic film patterned into isolated islands is used to direct assembly of superparamagnetic colloidal particles into two-dimensional arrays. Ferromagnetic islands positioned under a template of micro-wells are shown to promote highly regular 2D arrays, while external uniform magnetic field is used to bias the particles to attract or repel from the exposed end of the ferromagnetic islands. A theoretical analysis on the interactions between superparamagnetic colloidal particles with the template and external uniform magnetic fields is also presented.
Nonlinear forecasting for the classification of natural time series

There is a growing trend in the natural sciences to view time series as products of dynamical systems. This viewpoint has proven to be particularly useful in stimulating debate and insight into the nature of the underlying generating mechanisms. Here I review some of the issues concerning the use of forecasting in the detection of nonlinearities and possible chaos, particularly with regard to stochastic chaos. Moreover, it is shown how recent attempts to measure meaningful Lyapunov exponents for ecological data are fundamentally flawed, and that when observational noise is convolved with process noise, computing Lyapunov exponents for the real system will be difficult. Such problems pave the way for more operational definitions of dynamic complexity (cf. Yao & Tong, this volume) . Aside from its use in the characterization of chaos, nonlinear forecasting can be used more broadly in pragmatic classification problems. Here I review a recent example of nonlinear forecasting as it is applied to classify human heart rhythms. In particular, it is shown how forecast nonlinearity can be a good discriminator of the physiological effects of age, and how prediction-decay may discriminate heartdisease. In so doing, I introduce a method for characterizing nonlinearity using ‘S-maps’ and a method for analysing multiple short time series with composite attractors.
Goos–Hänchen and Imbert–Fedorov shifts at the interface of ordinary dielectric and topological insulator

Using Yasumoto and Oishi’s energy flux method, we evaluated the Goos–Hanchen (GH) and Imbert–Fedorov (IF) shifts of beam incident from the ordinary dielectric upon the topological insulator (TI) with totally internal reflection. Comparing with the case of two ordinary isotropic dielectrics, it is found that the topological parameter Θ of TI can affect two shifts. More important, IF shift appears even for a linear polarized TE or TM beam and achieves the maximum with elliptical polarization, which completely originates from the TI’s intrinsic magnetoelectric coupling effect. This observation provides an optical experimental approach to determine the topological parameters Θ and provide a new way to control the GH shift and IF shift.