Miracle-dz/UniFAR-FTUs huggingface dataset:
Analysis of Genetic Diversity and Resistance to Foliar Pathogens Based on Genotyping-by-Sequencing of a Para Rubber Diversity Panel and Progeny of an Interspecific Cross

Para rubber trees (Hevea brasiliensis) are the largest major source of natural rubber in the world. Its major pathogens are Phytophthora spp. , Corynespora cassiicola, and Colletotrichum spp. A rubber diversity panel of 116 clones using over 12,000 single nucleotide polymorphisms (SNPs) from DArTSeq genotyping revealed clear phylogenetic differences in clones that originated from different geographical regions of the world. An integrated linkage map constructed with an F1 progeny of 86 from an interspecific cross between H. brasiliensis and H. benthamiana using 23,978 markers [10,323 SNPs and 13,655 SilicoDArTs] spanned 3947.83 cM with 0.83 cM average marker-interval. The genome scaffolds that were anchored to the linkage map, covering 1.44 Gb of H. brasiliensis reference genome, revealed a high level of collinearity between the genetic map and reference genome. Association analysis identified 12 SNPs significantly associated with the resistance against Phytophthora, Corynespora, and Colletotrichum in six linkage groups: 2, 6, 12, 14, 17, and 18. Kompetitive Allele-Specific PCR marker assays were developed for those 12 SNPs, screened with 178 individuals, and detected clear separation between two genotypes. Within the proximity to those SNPs, 41 potentially key genes that have previously been reported to associate with plant disease resistance were predicted with high confidence.
The development of electron avalanches in argon at high E/N values. II. Boltzmann equation analysis

For pt.I see ibid., vol.10, no.7, p.1035 (1977). The electron swarm parameters for the steady-state Townsend, pulsed Townsend and time-of-flight experiments are calculated using a Boltzmann equation for argon at E/N values from 85 to 566 Td, when electron impact ionization is appreciable. The results suggest that the value of an electron swarm parameter depends on the type of the experiments involved, because of the presence of the ionization, in agreement with the Monte Carlo simulation work in the previous paper. The drift velocities and diffusion coefficients when ionization is present, are discussed.
Bank Customer Classification Model and Application Based on SVM

Based on the data mining method, support vector machine, technology and related analysis of variable selection methods, establishing binary classification model of VIP users and Ordinary users for commercial banks, executing classification prediction and results verifying on VIP users and Ordinary users of an Agricultural Bank in Changsha, and making comparative analysis on classification prediction accuracy and the time consuming when processing by comparing with neural network.
Detecting abnormalities on mammograms by bilateral comparison

An automated system for detecting breast abnormalities should significantly reduce the time needed to examine a mammogram. A system should be able to detect most kinds of abnormalities in order for it to have a positive contribution to a clinical situation. One way of examining mammograms that is used frequently by radiologists is the comparison of left and right breast images. Recent attempts to automate the comparison method have produced very promising results. Two new attempts are presented here. Initially, segmentation of the digitised images involves separating breast tissue from their background. Alignment of the 2 mammograms is then carried out using a single reference-the point of maximum curvature on the breast curve. Finally normalisation is used to minimise differences in illumination between X-ray images before comparison. The first method, single image comparison, involves finding corresponding areas whose intensities differ more than a preset threshold. The results are presented in the form of 2 binary images which are median filtered to eliminate artifacts and to smooth rough borders. The second method, multiple image comparison (MIG), involves generating 8 pairs of images for each original pair of left and right images. MIC uses a combination of processes including adaptive histogram modification, normalisation, grey level thresholding, binary image cleaning and region segmentation. The 8 pairs of images are then bilaterally compared and the resulting images recombined into 1 pair of images. (4 pages)
The automated measurement of CT number linearity using an ACR accreditation phantom

We developed a software to automatically measure the linearity between the CT numbers and densities of objects using an ACR 464 CT phantom, and investigated the CT number linearity of 16 different CT scanners. The software included a segmentation-rotation method. After segmenting five objects within the phantom image, the software computed the mean CT number of each object and plotted a graph between the CT numbers and densities of the objects. Linear regression and coefficients of regression, R2, were automatically calculated. The software was used to investigate the CT number linearity of 16 CT scanners from Toshiba, Siemens, Hitachi, and GE installed at 16 hospitals in Indonesia. The linearity of the CT number obtained on most of the scanners showed a strong linear correlation (R 2 > 0.99) between the CT numbers and densities of the five phantom materials. Two scanners (Siemens Emotion 16) had the strongest linear correlation with R 2 = 0.999, and two Hitachi Eclos scanners had the weakest linear correlation with R 2 < 0.99.
Performance of Conventional and Sharia Mutual Funds Using Sharpe, Treynor and Jensens Methods

Mutual funds is an instrument investment which is the best recommendation for beginner investor or an alternative investment that more safe and eficient. Investing growth give an opportunity to economic growth and to agregat growth of a country macro economic. That things were positive impacted to many factors for harmony and prospery. Research purpose - Indonesia is a country with the majorities moeslims citizen, to know how money market conventional and sharia mutual funds performances that can become a scient or subject to inform the investors of optional instrument investment it is does not depends to any religion. Using the portofolio method performance there are Sharpe Index, Treynor Index, and Jensen Alpha. And the variables using net asset value of money market mutual funds, risk free BI-7DRR, JKSE, and JII periode time 2017-2021. This research can show that mutual funds is a sustainable investment caused both of risk and return are the same. Research result In 2020 pandemic covid-19 hitten Indonesia and streamed untill 2022 but in the fact investment popularity doing hightly, a lot of campaign and promoting influencer to pull on teenegers become a new investor. Money market mutual fund is a suitable recommendation for investor beginner according with increased of under asset management value of money market mutual funds during pandemic. On the practice there are more options of mutual funds with two principle are conventional and sharia mutual funds.
Sexual dimorphism in relationships between of plasma urea and some psycho-neuro-endocrine parameters

Background. Earlier we found a strong urato-neural relationships in both men and women. Moreover, in women, the factor structure of the neural root is almost completely different from that in men. In addition, significant differences were found between the profiles of urato-neural correlations of women of reproductive age and postmenopausal women. The purpose of this study is to analyze the relationships between the plasma urea level and some psycho-neuro-endocrine parameters in the same cohort. Materials and Methods. The object of observation were almost healthy volunteers: 31 males (24÷69 y) and 30 females, from among them 18 postmenopausal (48÷76 y) and 12 of reproductive age (30÷45 y). In basal conditions we determined plasma levels of urea and adaptation hormones, estimated the severity of the trait and reactive anxiety, recorded the ongoing HRV and EEG. After 4 or 7 days, repeated testing was performed. Results. By building regression models with stepwise exclusion, it was found that in men plasma urea positively determines (R2=0,499) the level of circulating catecholamines and power spectrum density (PSD) of δ-, θ- and β-rhythms in different loci. In postmenopausal women, urea downregulates the amplitude and PSD of δ-rhythm in different loci, instead, it upregulates the PSD of α-rhythm in T5 locus, entropy of EEG in 2 loci and vagal tone. The degree of determination of neural parameters is 71,6%. In women of reproductive age the degree of determination of neural parameters is similar (69,9%), but the factor structure of the model is completely different. Urea upregulates the PSD of β-rhythm in F7 locus while downregulates the levels of reactive anxiety, vagal tone, entropy of EEG in 3 loci and P4-θ PSD as well as causes left lateralization of θ- and α-rhythms. Conclusion. Plasma urea has a modulating effect on EEG&HRV parameters, as well as reactive anxiety, but this effect is significantly different in men and women of different ages.
MR image reconstruction from undersampled data by using the iterative refinement procedure

Magnetic resonance imaging (MRI) reconstruction from sparsely sampled data has been a difficult problem in medical imaging field. We approach this problem by formulating a cost functional that includes a constraint term that is imposed by the raw measurement data in k‐space and the L1 norm of a sparse representation of the reconstructed image. The sparse representation is usually realized by total variational regularization and/or wavelet transform. We have applied the Bregman iteration to minimize this functional to recover finer scales in our recent work. Here we propose nonlinear inverse scale space methods in addition to the iterative refinement procedure. Numerical results from the two methods are presented and it shows that the nonlinear inverse scale space method is a more efficient algorithm than the iterated refinement method. (© 2008 WILEY‐VCH Verlag GmbH & Co. KGaA, Weinheim)
Changes in the structure of pulse signals under the impact of optical radiation of three colors

The paper presents the results of experimental studies of optical radiation impact of three colors (yellow, green and blue) on the functional state of human internal organs using the method of energy coefficient. It has been shown by quantitative assessment that a biological response of the body is not determined by the properties that are common to all the waves of the visible range, but it depends on the wavelength of optical radiation. Short-term exposure to optical radiation of the visible range does not lead to any significant and stable changes in the functioning of internal organs. The results of the research can be used to develop technologies for managing the mental and physiological state of a person.
On fuzzy control of nonlinear systems with large parameter uncertainties: fuzzy scheduler approach

This paper presents the design of a fuzzy scheduler which is robust enough to (1) stabilize an uncertain nonlinear system subject to large parameter uncertainties, and (2), give an acceptable closed-loop performance. Based on a fuzzy model with parameter uncertainty information, a stability criterion which involves solving an algebraic Riccati equation (ARE) is derived, and fuzzy controllers corresponding to the vertices of the operation parameter space (vertex fuzzy controllers) are designed. It is shown that the actual control signal can be interpolated by a proposed fuzzy scheduler from the control signals of vertex fuzzy controllers.
Metaphodioms: connecting metaphor and idioms

This paper aims to formulate the notion of metaphodiom and establish operational criteria for its definition by combining key insights emanating from quantitative corpus linguistics, the cognitive theory of metaphor, and a cognitive linguistic approach to idioms. To this end, the author selects boxing idioms for analysis, extracts their occurrences in the Corpus of Contemporary American English (COCA), and determines their structural, semantic, distributional, and discourse-functional properties. The paper makes a significant contribution to a growing body of literature on metaphorical idioms by systematically integrating all definitory parameters for their identification, description, and extraction from a large corpus of naturally-occurring data.
A new technique for measuring Young's modulus of electroplated nickel using AFM

This paper addresses a relatively simple method of measuring Young's modulus of electroplated nickel using an atomic force microscope. The thin layer of nickel to be measured is electroplated onto the tip side of an AFM silicon cantilever, whose Young's modulus and geometric dimensions are well defined from the manufacturer. The resonant frequency and quality factor of the electroplated AFM cantilever are measured by the tapping mode of the AFM and its spring constant is calculated using Sader's method. The spring constant of the electroplated cantilever is also calculated by using the laminar composite beam theory. Comparing two spring constants, Young's modulus of electroplated nickel is determined. The measured Young's modulus of nickel at the end of each plating step ranged between 148.04 GPa and 159.90 GPa with a relative uncertainty of 4.21%.
Establishment of a diverse head and neck squamous cancer cell bank using conditional reprogramming culture methods

Most laboratory models of head and neck squamous cell cancer (HNSCC) rely on established immortalized cell lines, which carry inherent bias due to selection and clonality. We established a robust panel of HNSCC tumor cultures using a “conditional reprogramming” (CR) method, which utilizes a rho kinase inhibitor (Y‐27632) and co‐culture with irradiated fibroblast (J2 strain) feeder cells to support indefinite tumor cell survival. Sixteen CR cultures were successfully generated from 19 consecutively enrolled ethnically and racially diverse patients with HNSCC at a tertiary care center in the Bronx, NY. Of the 16 CR cultures, 9/16 were derived from the oral cavity, 4/16 were derived from the oropharynx, and 3/16 were from laryngeal carcinomas. Short tandem repeat (STR) profiling was used to validate culture against patient tumor tissue DNA. All CR cultures expressed ΔNp63 and cytokeratin 5/6, which are markers of squamous identity. Human papillomavirus (HPV) testing was assessed utilizing clinical p16 staining on primary tumors, reverse transcription polymerase chain reaction (RT‐PCR) of HPV16/18‐specific viral oncogenes E6 and E7 in RNA extracted from tumor samples, and HPV DNA sequencing. Three of four oropharyngeal tumors were p16 and HPV‐positive and maintained HPV in culture. CR cultures were able to establish three‐dimensional spheroid and murine flank and orthotopic tongue models. CR methods can be readily applied to all HNSCC tumors regardless of patient characteristics, disease site, and molecular background, providing a translational research model that properly includes patient and tumor diversity.
When and How Slow Motion Makes Products More Luxurious

This research examines when and how the speed of video ads influences consumers’ perceptions of luxuriousness and their subsequent behaviors toward products or brands featured in the ads. Across 12 experiments (total N = 27,227, five preregistered), the authors demonstrate that when a video ad depicts a product in slow motion (vs. regular speed), consumers perceive the featured product or brand as more luxurious. The effect emerges across various product categories (chocolate, shampoo, mineral water, wine) and in different countries (United States, United Kingdom, France). Tests of mediation and moderation suggest that the effect occurs because viewing a slow-motion ad increases feelings of immersion, which lead consumers to expect greater hedonic value from the featured product and thus view it as more luxurious. Consistent with this account, the effect weakens when video blurriness or buffering impairs the immersive viewing experience afforded by slow motion, and the effect attenuates among consumers who are very weakly or very strongly predisposed to experience immersion. Finally, by enhancing perceptions of luxuriousness, slow motion subsequently boosts consumers’ desire for the featured product or brand (as manifested by higher willingness to pay, purchase intentions, and ad click rates), particularly when the goal to consume luxury is salient (vs. not).
How COVID-19 Phases Have Impacted Psychiatric Risk: A Retrospective Study in an Emergency Care Unit for Adolescents

Dramatic events during the COVID-19 pandemic have acutely impacted the psychosocial environment worldwide, with negative implications for mental health, particularly for more vulnerable children and adolescents with severe psychiatric illnesses. Some data suggest that the pandemic waves may have produced different psychopathological consequences, further worsening in the second phase of the pandemic, compared to those in the first lockdown, soon after March 2020. To test the hypothesis of a further worsening of psychiatric consequences of COVID-19 in the second lockdown compared to the first lockdown, we focused our analysis on a consecutive sample of youth referred to a psychiatric emergency unit for acute mental disorders in the time period between March 2019–March 2021. The sample, consisting of 241 subjects (123 males and 118 females, ranging in age from 11 to 17 years), was divided into three groups: Pre-Lockdown Group (PLG, 115 patients); First Lockdown Group (FLG, 65 patients); and Second Lockdown Group (SLG, 61 patients). Patients in the SLG presented more frequently with non-suicidal self-injuries (NSSIs), suicidal ideation, and suicidal behavior, while no significant differences in self-harm were found between PLG and FLG. Eating disorders were more frequent in both the FLG and SLG, compared to the PLG, while sleep problems were higher only in the SLG. Furthermore, patients in the SLG presented with more frequent psychological maltreatments and neglect, as well as with psychiatric disorders in the parents. Adverse traumatic experiences and internalizing disorders were significantly associated with an increased risk of suicidality. Intellectual disability was less represented from the PLG to SLG, and similarly, the rate of ADHD was lower in the SLG. No differences were found for the other psychiatric diagnoses. This information may be helpful for a better understanding and management of adolescents with severe emotional and behavioral disorders after the exposure to long-lasting collective traumas.
Diagnostic, Prognostic, and Immunological Roles of FABP4 in Pancancer: A Bioinformatics Analysis

Background Fatty acid binding protein 4 (FABP4) is mainly involved in the regulation of systemic metabolism through various lipid signaling pathways. Metabolic reprogramming is one of the important factors in the development and progression of cancer. It has been recently reported that FABP4 is closely related to the development of cancer and may be involved in tumor invasion and metastasis. Methods In this study, we explored the expression pattern of FABP4 in pancancer through TCGA and CPTAC. Using TCGA, Kaplan-Meier Plotter, and STRING databases, to explore its diagnostic and prognostic value, and function through GO/KEGG and GSEA. Then, using the TIMER2.0 database, we investigated the correlation between FABP4 expression and immune infiltration in cancers, especially stomach adenocarcinomas (STAD) and colorectal adenocarcinoma (COADREAD). Results Compared with normal tissues, the expression of FABP4 in more than 10 tumor tissues was lower (p < 0.05). Through the receiver operating characteristic (ROC) curve, the diagnostic value was found higher in colorectal cancer, breast cancer, thyroid cancer, and lung cancer, with the area under the curve (AUC) > 0.9. Through the K-M curve, FABP4 was found to correlate to the prognosis of various cancers. The results of gastric cancer and colorectal cancer are consistent. The low-expression group has a better prognosis than the high-expression group, and the expression of FABP4 in the early T and N stages of gastrointestinal tumors is lower. FABP4 highly expressed gene set is mostly enriched in extracellular matrix degradation and cell adhesion functions. Gastrointestinal tumors with high expression of FABP4 may have more immunosuppressive effects on macrophages and have a worse prognosis. Conclusion FABP4 can be used as a diagnostic and prognostic biomarker in pancancer, and its high expression in gastrointestinal tumors suggests poor prognosis. This may be correlated to the immune infiltration of macrophages and epithelial-mesenchymal transition.
Demonstration of a directly written directional coupler using UV-induced photosensitivity in a planar silica waveguide

The authors report, for the first time, the demonstration of a UV directly written directional coupler in a planar silica waveguide on silicon. From the device parameters and the measured spectral characteristics, the UV-induced index change is calculated to be 0.0075. This is the highest photoinduced refractive index change reported to date in a planar silica waveguide.
Fourier Transform Infrared Spectroscopic Analysis of Plastic Capsule Materials Exposed to Deuterium-Tritium (DT) Gas

Abstract Planar samples of varying thicknesses of both CH and CD glow discharge polymer have been measured with Fourier transform infrared (FTIR) spectroscopy before and after exposure to deuterium-tritium (DT) gas at elevated temperature and pressure. Planar samples of polyimide films made from both hydrogenated and deuterated precursors have also been examined by FTIR before and after DT exposure. The post-exposure FTIR spectra demonstrated no measurable exchange of hydrogen with deuterium or tritium for either polymer. Evidence for oxidation of the glow discharge polymer due to atmospheric oxygen was the only chemical change indicated by the FTIR data.
Nuclear hyper-deformation and the Jacobi shape transition

Large-scale macroscopic–microscopic calculations taking into account thermal effects are performed in the mass A∼130 nuclei to search for hyper-deformation (HD). An emphasis is set on the role of the Jacobi shape transition for the population of hyper-deformed states. The hyper-deformed configurations are predicted to exist at the very high spins only, in contrast to the super-deformed ones. Moments of inertia are calculated and compared with experiment, showing good agreement.
Quantitative Targeted Absolute Proteomics for Better Characterization of an In Vitro Human Blood–Brain Barrier Model Derived from Hematopoietic Stem Cells

We previously developed an in vitro model of the human blood–brain barrier (BBB) based on the use of endothelial cells derived from CD34+-hematopoietic stem cells and cultured with brain pericytes. The purpose of the present study was to provide information on the protein expression levels of the transporters, receptors, tight junction/adherence junction molecules, and transporter-associated molecules of human brain-like endothelial cells (hBLECs). The absolute protein expression levels were determined by liquid chromatography–mass spectrometry-based quantitative targeted absolute proteomics and compared with those from human brain microvessels (hBMVs). The protein levels of CD144, CD147, MRP4, Annexin A6 and caveolin-1 showed more than 3-fold abundance in hBLECs, those of MCT1, Connexin 43, TfR1, and claudin-5 showed less than 3-fold differences, and the protein levels of other drug efflux transporters and nutrient transporters were less represented in hBLECs than in hBMVs. It is noteworthy that BCRP was more expressed than MDR1 in hBLECs, as this was the case for hBMVs. These results suggest that transports mediated by MCT1, TfR1, and claudin-5-related tight junction function reflect the in vivo BBB situation. The present study provided a better characterization of hBLECs and clarified the equivalence of the transport characteristics between in vitro BBB models and in vivo BBB models using LC-MS/MS-based protein quantification.