Miracle-dz/UniFAR-FTUs huggingface dataset:
Scaling Input Signal Swings of Overloaded Integrators in Resonator-based Sigma-Delta Modulators

Overloading of the integrators in loop filter of sigma-delta modulators is a performance degrading factor in circuit implementations. In this paper, it is shown that in resonator-based SigmaDelta modulators scaling factors should be introduced in order to adjust the integrators' input. A systematic method is presented to calculate these scaling factors without modifying the noise and signal transfer functions. The effect of the scaling factors on circuit implementation is also discussed. Several examples are given to illustrate the influence of the scaling factors on the SigmaDelta performances depending on the order, architecture and number of bits of the quantizer.
Audio-based gender identification using bootstrapping

Annotation of audio content is an important component of modern multimedia information retrieval systems. Automatic gender identification is used for video indexing and can improve speech recognition results by using gender-specific classifiers. Gender identification in large datasets is difficult because of the large variability in speaker characteristics. Bootstrapping is an approach that attempts to combine minimal user annotations with automatic techniques for audio classification. In bootstrapping a small random sampling of the training data is annotated by the user and this annotation is used to train a classifier that annotates the remaining data. This technique is useful when the training set is too large to be fully annotated by the user. Experimental results showing that bootstrapping is effective for automatic audio-based gender identification are provided.
Surgical Anatomy of the Ligamentous Attachments in the Temple and Periorbital Regions

This study documents the anatomy of the deep attachments of the superficial fasciae within the temporal and periorbital regions. A highly organized and consistent three-dimensional connective tissue framework supports the overlying skin and soft tissues in these areas. The regional nerves and vessels display constant and predictable relationships with both the fascial planes and their ligamentous attachments. Knowledge of these relationships allows the surgeon to use the tissue planes and soft-tissue ligaments as intraoperative landmarks for the vital neurovascular structures. This results in improved efficiency and safety for aesthetic procedures in these regions.
Image enhancement for outdoor long-range surveillance using IQ-learning multiscale Retinex

The visible light camera-based long-range surveillance always suffers from the complex atmosphere. When applying some traditional image enhancement methods, the computational effects behave limited because of their poor environment adaptability. To conquer that problem, a blind image quality (IQ) learning-based multiscale Retinex, i.e. the IQ-learning multiscale Retinex, is proposed. First, a series of typical degenerated images are collected. Second, several blind IQ evaluation metrics are computed for the dataset above. They are the image brightness degree, the image region contrast degree, the image edge blur degree, the image colour quality degree, and the image noise degree. Third, a wavelet transform multi-scale Retinex (WT_MSR) is used to carry out the basic image enhancement. A kind of optimal enhancement is implemented by the subjective evaluation and tuning of multiple optimal control parameters (MOCPs) of WT_MSR for these degenerated dataset. Fourth, the back propagation neural network (BPNN) is used to build a connection between the IQ metrics and the MOCPs. Finally, when a new image is captured, this system will compute its IQ metrics and estimate the MOCPs for the WT_MSR by BPNN; then a kind of optimal enhancement can be realised. Many outdoor applications have shown the effectiveness of proposed method.
External EMI effects on a CMOS circuit in a cavity with an aperture

This paper explores the disruption of a simple CMOS circuit in a rectangular cavity with a rectangular aperture. The CMOS circuit is fed by a microstrip line on the back face of the cavity opposite to the aperture. A cavity transfer function is determined that relates the E-field strength at the face of the cavity to a voltage at the input to the first gate of a 4-bit full adder circuit. Various waveshapes are analyzed using the cavity transfer function to get a modified wave at the input to the circuit and then determine the relative bit error rates of the various interference waveforms.
Evidence-based resistance training recommendations

Resistance training produces an array of health benefits, as well as the potential to promote muscular adaptations of strength, size, power and endurance. The American College of Sports Medicine (ACSM) regularly publish a position stand making recommendations for optimal achievement of the desired training goals. However, the most recent position stand (as well as previous ones) has come under heavy criticism for misrepresentation of research, lack of evidence and author bias. Therefore this paper proposes a set of scientifically rigorous resistance training guidelines, reviewing and summarising the relevant research for the purpose of proposing more logical, evidence-based training advice. We recommend that appreciably the same muscular strength and endurance adaptations can be attained by performing a single set of ~8-12 repetitions to momentary muscular failure, at a repetition duration that maintains muscular tension throughout the entire range of motion, for most major muscle groups once or twice each week. All resistance types (e.g. free-weights, resistance machines, bodyweight, etc.) show potential for increases in strength, with no significant difference between them, although resistance machines appear to pose a lower risk of injury. There is a lack of evidence to suggest that balance from free weights or use of unstable surfaces shows any transference to sporting improvement, and explosive movements are also not recommended as they present a high injury risk and no greater benefit than slow, controlled weight training. Finally, we consider genetic factors in relation to body type and growth potential.
Neural responses to affective and cognitive theory of mind in children with conduct problems and varying levels of callous-unemotional traits.

CONTEXT Reduced neural responses to others' distress is hypothesized to play a critical role in conduct problems coupled with callous-unemotional traits, whereas increased neural responses to affective stimuli may accompany conduct problems without callous-unemotional traits. Heterogeneity of affective profiles in conduct problems may account for inconsistent neuroimaging findings in this population. OBJECTIVES To broaden understanding of neural processing in conduct problems using an affective processing task including an empathy component as well as to explore dimensional contributions of conduct problems symptoms and callous-unemotional traits to variance in affective neural responses. DESIGN Case-control study. SETTING On-campus neuroimaging facility. PARTICIPANTS Thirty-one boys with conduct problems (mean age, 14.34 years) and 16 typically developing control subjects (mean age, 13.51 years) matched for age (range, 10-16 years), IQ, socioeconomic status, handedness, and race/ethnicity. Participants were recruited using screening questionnaires in a community-based volunteer sample. MAIN OUTCOME MEASURES Functional magnetic resonance imaging of a task contrasting affective and cognitive theory of mind judgments. RESULTS Relative to typically developing children, children with conduct problems showed reduced activation in right amygdala and anterior insula for affective vs cognitive theory of mind judgments. Furthermore, in the right amygdala, regression analysis within the conduct-problems group showed suppressor effects between ratings of conduct problems and callous-unemotional traits. Specifically, unique variance associated with conduct problems was positively correlated with amygdala reactivity, whereas unique variance associated with callous-unemotional traits was negatively correlated with amygdala reactivity. These associations were not explained by hyperactivity, depression/anxiety symptoms, or alcohol use ratings. CONCLUSIONS Childhood conduct problems are associated with amygdala and anterior insula hypoactivity during a complex affective processing task including an empathy component. Suppressor effects between conduct problems and callous-unemotional traits in the amygdala suggest a potential neural substrate for heterogeneity in affective profiles associated with conduct problems.
New Insights in the Mobilization of Hematopoietic Stem Cells in Lymphoma and Multiple Myeloma Patients

Following chemotherapy and/or the administration of growth factors, such as granulocyte-colony stimulated factor (G-CSF), hematopoietic stem cells (HSC) mobilize from bone marrow to peripheral blood. This review aims to systematically present the structure of the HSC “niche” and elucidate the mechanisms of their mobilization. However, this field is constantly evolving and new pathways and molecules have been shown to contribute to the mobilization process. Understanding the importance and the possible primary pathophysiologic role of each pathway is rather difficult, since they share various overlapping components. The primary initiating event for the mobilization of HSC is chemotherapy-induced endogenous G-CSF production or exogenous G-CSF administration. G-CSF induces proliferation and expansion of the myelomonocytic series, which leads to proteolytic enzyme activation. These enzymes result in disruption of various receptor-ligand bonds, which leads to the disanchorage of HSC from the bone marrow stroma. In everyday clinical practice, CXC chemokine receptor-4 (CXCR4) antagonists are now being used as mobilization agents in order to improve HSC collection. Furthermore, based on the proposed mechanisms of HSC mobilization, novel mobilizing agents have been developed and are currently evaluated in preclinical and clinical studies.
In vitro demonstration of cell-mediated immunity to human brain tumors.

Our studies showed that patients with primary intracranial neoplasms, both well differentiated and anaplastic, intra- and extracerebral, possessed peripheral blood lymphocytes that in vitro were specifically cytotoxic to tissue-cultured, autogenous tumor cells. Some studies suggested antigenic cross-reactivity between glioblastoma cells from different patients and, moreover, between glioblastoma and melanoma cells. One melanoma patient possessed lymphocytes cytotoxic to his tumor cells and to allogeneic glioblastoma cells, as well as to the tumor cells and normal glial cells, but not to the normal fibroblasts, of a patient with a ganglioglioma.
Effects of feeding metabolite combinations produced by Lactobacillus plantarum on growth performance, faecal microbial population, small intestine villus height and faecal volatile fatty acids in broilers

1. Four combinations of metabolites produced from strains of Lactobacillus plantarum were used to study the performance of broiler chickens. 2. A total of 432 male Ross broilers were raised from one-day-old to 42 d of age in deep litter pens (12 birds/pen). These birds were divided into 6 groups and fed on different diets: (i) standard maize–soybean-based diet (negative control); (ii) standard maize–soybean-based diet + Neomycin and Oxytetracycline (positive control); (iii) standard maize–soybean-based diet + 0·3% metabolite combination of Lactobacillus plantarum RS5, RI11, RG14 and RG11 strains (com3456); (iv) standard maize–soybean-based diet + 0·3% metabolite combination of L. plantarum TL1, RI11 and RG11 (Com246); (v) standard maize–soybean-based diet + 0·3% metabolite combination of L. plantarum TL1, RG14 and RG11 (Com256) and (vi) standard maize–soybean-based diet + 0·3% metabolite combination of L. plantarum TL1, RS5, RG14 and RG11 (Com2356). 3. Higher final body weight, weight gain, average daily gain and lower feed conversion ratio were found in all 4 treated groups. 4. The addition of a metabolite combination supplementation also increased faecal lactic acid bacteria population, small intestine villus height and faecal volatile fatty acids and faecal Enterobacteriaceae population.
[Proteomics study on the essence of wind syndrome caused by gan-yang hyperactivity in Chinese medicine].

OBJECTIVE To preliminarily study the essence of wind syndrome caused by Gan-yang hyperactivity (WSGH) in Chinese medicine at the protein expression level. METHODS WSGH was strictly differentiated from wind stirring due to yin deficiency syndrome in patients with intracerebral hemorrhage (ICH) and those with cerebral infarction (CI); from Gan-yang hyperactivity syndrome in patients with cervical spondylosis (CS); from wind syndrome induced by blood deficiency in patients with Parkinson's disease (PD) according to Chinese medicine syndrome typing standard. Control studies were performed. Peripheral blood mononuclear cells (PBMCs) were isolated from all patients of the aforesaid syndromes and healthy subjects. The total proteins were extracted, two-dimensional gel electrophoresis (2-DE) conducted and analyzed by PDQuest software. The peptide mass fingerprint (PMF) was determined using matrix-assisted laser desorption/ionization time of flight mass spectrometry (MALDI-TOF-MS). The SwissProt database was inquired using Mascot reference system. Proteins of different and same expressions in PBMCs of patients suffering from the same disease of different syndromes, different diseases of the same syndrome, and syndromes of the same kind were compared. RESULTS The 2-DE map of PBMCs' total proteins in the aforesaid syndrome groups and healthy subjects was established. Through comparison, analysis, and appraisement, there was 1 protein dot of the same expression and 22 protein dots of different expressions between ICH patients of WSGH and ICH patients of wind stirring due to yin deficiency syndrome. There were 6 protein dots of the same expression and 21 protein dots of different expressions between CI patients of WSGH and CI patients of wind stirring due to yin deficiency syndrome. There were 3 protein dots of the same expression and 12 protein dots of different expressions between CS patients of WSGH and CS patients of Gan-yang hyperactivity syndrome. There was no protein dot of the same expression and 12 protein dots of different expressions between PD patients of WSGH and PD patients of wind syndrome induced by blood deficiency. There were 13 protein dots of the same expression in different diseases of the same syndrome. There was 1 protein dot (Thioredoxin-dependent peroxide reductase, TPx) of the same expression in the four diseases of the same kind syndrome. CONCLUSIONS Different connotations of the essence existed (having multiple different protein expressions) in patients with the same disease of different syndromes. Syndromes of the same kind share the same material bases (having the same protein expression). These suggested that Chinese medicine syndrome has its own material bases and essence findable.
Change in working landscape and new career opportunities for women in ITES

Career plays a significant role among current generation. Everyone plans for a successful career. In today's scenario everyone is running behind the opportunity to exhibit their talents for a planned career goal. Most of the working population still mess up with the term “job” and “career”, this leads to confused state as no means to ends. Career has different prospect among men and women. Normally career development, career planning, and career success is lined in with men than women in India. But various recent researches proved that today's women are given equal opportunity like men, they are supported by the organisation policy and procedures to break the problems on career resilience, glass ceiling etc. The corporate world is opened for women, the capability and intelligence of women are most welcomed in new sectors, and the opportunities are more for the women. For a decade 24/7 environment is becoming a reality. The ITeS sector works in a parallel approach. The ITeS centres offer several opportunities to women workforce. The IT enabled services require excellent verbal communication skills and pleasing personality.
Beginning teachers’ responses to education reform agendas

ABSTRACT National education reform agendas are increasingly prevalent in school systems around the world. Whilst we have a substantial body of research exploring the ways in which schools manage change agendas, there is less discussion of the impacts these agendas may have on beginning teachers and their retention in the profession. Here I report on a study of 14 beginning teachers at a time when two major reforms were being introduced – national standardised literacy teaching and the public reporting of those results. I describe the ways in which these reforms were experienced by the teachers and discuss the implications for school leaders seeking to support beginning teachers in their schools.
Pengaruh Kinerja People dan Physical Evidence Terhadap Keputusan Menginap

Seiring dengan perkembangan di segala bidang, mengakibatkan situasi pasar saat ini telah berubah dengan sangat cepat. Persaingan terjadi pada seluruh industri baik produk maupun jasa, salah satunya adalah industri perhotelan. Menurunnya tingkat hunian kamar di Kabupaten Garut menjadikan industri ini semakin kompetitif dan saling bersaing dalam memberikan layanan. Salah satu hotel yang ikut berperan dalam industri perhotelan di Kabupaten Garut adalah Hotel Kampung Sumber Alam. Hal tersebut membuat Hotel Kampung Sumber Alam Garut menciptakan strategi untuk meningkatkan keputusan menginap melalui kinerja people dan physical evidence yang dapat memberikan kesan dan pengalaman tersendiri bagi para tamunya. Penelitian ini bertujuan untuk 1) memperoleh temuan mengenai kinerja people di Hotel Kampung Sumber Alam Garut, 2) memperoleh temuan mengenai physical evidence di Hotel Kampung Sumber Alam Garut, 3) memperoleh temuan keputusan menginap di Hotel Kampung Sumber Alam Garut, 4) memperoleh temuan mengenai seberapa besar pengaruh kinerja people dan physical evidence terhadap keputusan menginap tamu Hotel Kampung Sumber Alam Garut baik secara simultan maupun parsial. Objek penelitian ini adalah tamu Hotel Kampung Sumber Alam Garut. Variabel eksogen dalam penelitian ini adalah kinerja people dan physical evidence dan variabel endogen yaitu keputusan menginap dengan jenis penelitian yang digunakan adalah deskriptif, verifikatif, dan metode yang digunakan adalah explanatory survey dengan teknik simple random sampling dengan jumlah sampel 100 responden. Teknik analisa data yang digunakan adalah path analysis dengan alat bantu software komputer SPSS 21.0 for windows. Hasil yang diperoleh dalam penelitian menyatakan bahwa kinerja people dan physical evidence berpengaruh terhadap keputusan menginap sebesar empat puluh sembilan persen. Dari hasil penelitian terhadap pengujian hipotesis dapat diketahui bahwa kinerja people dan physical evidence memiliki pengaruh yang positif terhadap keputusan menginap
Mitochondrial Oxidative Phosphorylation Is Impaired in Patients with Congenital Lipodystrophy

Objective: Lipid accumulation in skeletal muscle and the liver is strongly implicated in the development of insulin resistance and type 2 diabetes, but the mechanisms underpinning fat accrual in these sites remain incompletely understood. Accumulating evidence of muscle mitochondrial dysfunction in insulin-resistant states has fuelled the notion that primary defects in mitochondrial fat oxidation may be a contributory mechanism. The purpose of our study was to determine whether patients with congenital lipodystrophy, a disorder primarily affecting white adipose tissue, manifest impaired mitochondrial oxidative phosphorylation in skeletal muscle. Research Design and Methods: Mitochondrial oxidative phosphorylation was assessed in quadriceps muscle using 31P-magnetic resonance spectroscopy measurements of phosphocreatine recovery kinetics after a standardized exercise bout in nondiabetic patients with congenital lipodystrophy and in age-, gender-, body mass index-, and fitness-matched controls. Results: The phosphocreatine recovery rate constant (k) was significantly lower in patients with congenital lipodystrophy than in healthy controls (P < 0.001). This substantial (∼35%) defect in mitochondrial oxidative phosphorylation was not associated with significant changes in basal or sleeping metabolic rates. Conclusions: Muscle mitochondrial oxidative phosphorylation is impaired in patients with congenital lipodystrophy, a paradigmatic example of primary adipose tissue dysfunction. This finding suggests that changes in mitochondrial oxidative phosphorylation in skeletal muscle could, at least in some circumstances, be a secondary consequence of adipose tissue failure. These data corroborate accumulating evidence that mitochondrial dysfunction can be a consequence of insulin-resistant states rather than a primary defect. Nevertheless, impaired mitochondrial fat oxidation is likely to accelerate ectopic fat accumulation and worsen insulin resistance.
ANALYSIS OF LTE-ADVANCED CAPACITY AND DATA RATES PERFORMANCE UNDER HIGH BROADBAND DEMAND

In the recent years followed by strongly growth, mobile broadband starts governing the traffic. For the purpose of satisfying user it is from high importance mobile network operators to assess the needed network capacity, when facing the boosting demand and shortage of the available spectrum. The deployment of 3G and nowadays 4G has resulted in increased capacity, but due to the essential shift of the traffic balance of the mobile networks caused by broadband data load, the support of the much higher peak rates, higher throughput and coverage will become necessity soon. LTE-Advanced (or LTE Release 10) is expected more and more to significantly enhance the LTE Release 8 resulting in a better user experience. Altogether, this paper addresses the high level analysis of LTE-Advanced capacity and data rates dimensioning as key issue being considered for the future.
Procedural Texture Synthesis for Zoom‐Independent Visualization of Multivariate Data

Simultaneous visualization of multiple continuous data attributes in a single visualization is a task that is important for many application areas. Unsurprisingly, many methods have been proposed to solve this task. However, the behavior of such methods during the exploration stage, when the user tries to understand the data with panning and zooming, has not been given much attention.
HLA-G Orchestrates the Early Interaction of Human Trophoblasts with the Maternal Niche

Extravillous trophoblasts (EVTs) play a central role in educating maternal leukocytes, endometrial stromal and endothelial cells to generate a receptive decidual microenvironment tailored to accept the semi-allogeneic fetus. HLA-G, a non-classical HLA class I molecule endowed with immune-regulatory functions, is primarily expressed on EVTs lining the placenta and on the naturally occurring tolerogenic dendritic cells, named DC-10, which are enriched in the human first trimester decidua. Decidual DC-10 are involved in HLA-G-mediated tolerance at the maternal–fetal interface. EVTs not only establish a tolerogenic microenvironment through the interaction with maternal innate and adaptive cells but also orchestrate placenta vascular and tissue remodeling, leading to a successful pregnancy. Here, we discuss the potential implications of the HLA-G-mediated cross-talk among the cells present at the maternal–fetal interface, and its role in maintaining a positive relationship between the mother and the fetus.