Miracle-dz/UniFAR-FTUs huggingface dataset:
CEO Ideational Facilitation Leadership and Team Creativity: The Mediating Role of Knowledge Sharing.

The development of new ventures is often based on collective creative efforts. We conceptualize team creativity as a process of looking for and exploring new solutions and examine whether and how CEO leadership fosters creativity in top management teams (TMT). Data collected from senior executive teams indicate that CEO ideational facilitation leadership is positively related to team knowledge sharing, which in turn results in enhanced team exploratory behaviors. These findings bear important theoretical implications for ways in which leaders can enhance creativity in teams and augment the entrepreneurial direction of executive teams.
The E2F–Cdc2 Cell-Cycle Pathway Specifically Mediates Activity Deprivation-Induced Apoptosis of Postmitotic Neurons

Neuronal apoptosis plays a critical role in the normal development of the mammalian brain and is thought to contribute to the pathogenesis of several neurologic disorders. However, the intracellular mechanisms underlying apoptosis of neurons remain incompletely understood. In the present study, we characterized a cell-cycle-based mechanism by which neuronal activity deprivation induces apoptosis of postmitotic neurons. Activity deprivation, but not growth factor withdrawal, was found to induce Cdc2 expression and consequent Cdc2-mediated apoptosis in granule neurons of the developing rat cerebellum. We found that activity deprivation induces cdc2 transcription in neurons via an E2F-binding element (EBE) within the cdc2 promoter. The transcription factor E2F1 that is expressed in granule neurons was found in DNA binding assays to bind to the EBE of the cdc2gene. In chromatin immunoprecipitation analysis, endogenous E2F1 forms a complex with the promoter of the endogenous cdc2 gene in granule neurons, indicating that endogenous E2F1 is poised to activate transcription of the endogenous cdc2 gene in neurons. Consistent with this conclusion, a dominant interfering form of E2F, when expressed in granule neurons, blocked activity deprivation-inducedcdc2 transcription. In other experiments, we found that the expression of E2F1 in granule neurons induces Cdc2 expression and promotes neuronal apoptosis via the activation of Cdc2. Remarkably, in contrast to inducing the E2F-mediated expression and activation of Cdc2 in granule neurons, activity deprivation fails to stimulate the expression of E2F-target genes that trigger DNA synthesis and replication. Together, our findings define a novel apoptotic mechanism whereby E2F selectively couples an activity deprivation-induced signal to cdc2 transcription in the absence of stimulating DNA synthesis and thus culminating in Cdc2-mediated apoptosis of postmitotic neurons.
Diagnose – then act. Some thoughts on training today

Purpose – This paper seeks to reinforce an awareness that the forces driving the business world today have changed quite dramatically in the last few years. Training must respond to this and become more actively involved in the quest for higher productivity. The article also aims to introduce a new factor into long‐range planning.Design/methodology/approach – The paper identifies and describes these changes and discusses possible reactions.Findings – This article expresses a concern that if short‐course programs continue to focus on resolving procedural issues the needs of wider issues today may be down‐played.Originality/value – The paper reiterates that the outcome of a training program should demonstrate the skill/knowledge gain and enhance the motivation to extend it.
Fast Mesh interpolation and Mesh Decomposition with Applications

A new approach for constructing a smooth subdivision surface to interpolate the vertices of an arbitrary mesh is presented. The construction process does require setting up neither any linear systems, nor any matrix computation, but is simply done by iteratively moving vertices of the given mesh locally until control mesh of the required interpolating surface is reached. The new interpolation method has the simplicity of a local method in effectively dealing with meshes of a large number of vertices. It also has the capability of a global method in faithfully resembling the shape of a given mesh. Furthermore, the new method is fast and does not require a fairing step in the construction process because the iterative process converges to a unique solution at an exponential rate. Another important result of this work is, with the new iterative process, each mesh (surface) can be decomposed into a sum of simpler meshes (surfaces) which carry high-and low-frequency information of the given model. This mesh decomposition scheme provides us with new approaches to some classic applications in computer graphics such as texture mapping, denoising/smoothing/sharpening, and morphing. These new approaches are demonstrated in this paper and test results are included.
State of the Art Robotic Grippers and Applications

In this paper, we present a recent survey on robotic grippers. In many cases, modern grippers outperform their older counterparts which are now stronger, more repeatable, and faster. Technological advancements have also attributed to the development of gripping various objects. This includes soft fabrics, microelectromechanical systems, and synthetic sheets. In addition, newer materials are being used to improve functionality of grippers, which include piezoelectric, shape memory alloys, smart fluids, carbon fiber, and many more. This paper covers the very first robotic gripper to the newest developments in grasping methods. Unlike other survey papers, we focus on the applications of robotic grippers in industrial, medical, for fragile objects and soft fabrics grippers. We report on new advancements on grasping mechanisms and discuss their behavior for different purposes. Finally, we present the future trends of grippers in terms of flexibility and performance and their vital applications in emerging areas of robotic surgery, industrial assembly, space exploration, and micromanipulation. These advancements will provide a future outlook on the new trends in robotic grippers.
Software Quality: The Elusive Target

If you are a software developer, manager, or maintainer, quality is often on your mind. But what do you really mean by software quality? Is your definition adequate? Is the software you produce better or worse than you would like it to be? We put software quality on trial, examining both the definition and evaluation of our software products and processes.
Reduced fetal growth rate and increased risk of death from ischaemic heart disease: cohort study of 15 000 Swedish men and women born 1915-29

Abstract Objective: To establish whether fetal growth rate (as distinct from size at birth) is associated with mortality from ischaemic heart disease. Design: Cohort study based on uniquely detailed obstetric records with 97% follow up over the entire life course and linkage to census data in adult life. Subjects: All 14 611 babies delivered at the Uppsala Academic Hospital, Sweden, during 1915-29 followed up to end of 1995. Main outcome measures: Mortality from ischaemic heart disease and other causes. Results: Cardiovascular disease showed an inverse association with birth weight for both men and women, although this was significant only for men. In men a 1000 g increase in birth weight was associated with a proportional reduction in the rate of ischaemic heart disease of 0.77 (95% confidence interval 0.67 to 0.90). Adjustment for socioeconomic circumstances at birth and in adult life led to slight attenuation of this effect. Relative to the lowest fourth of birth weight for gestational age, mortality from ischaemic heart disease in men in the second, third, and fourth fourths was 0.81 (0.66 to 0.98), 0.63 (0.50 to 0.78), and 0.67 (0.54 to 0.82), respectively. The inclusion of birth weight per se and birth weight for gestational age in the same model strengthened the association with birth weight for gestational age but removed the association with birth weight. Conclusions: This study provides by far the most persuasive evidence of a real association between size at birth and mortality from ischaemic heart disease in men, which cannot be explained by methodological artefact or socioeconomic confounding. It strongly suggests that it is variation in fetal growth rate rather than size at birth that is aetiologically important.
Socioeconomic status and self-reported oral health in Iranian adolescents: the role of selected oral health behaviors and psychological factors.

OBJECTIVES This study investigated health inequality for self-reported oral health outcomes among adolescents. The role of oral health behaviors and psychological factors in explaining oral health inequality was investigated using the hypothesis of mediation. METHODS This was a cross-sectional study that used self-completed questionnaires. This study sampled 639 (315 male and 324 female) 15- to 17-year-old adolescents (second and third grade high school students) of both sexes in the city of Sanandaj in the province of Kurdistan, western Iran. Socioeconomic indicators of the study were subjective socioeconomic status, wealth index, and parental education. Oral health behaviors were measured as toothbrushing frequency, dental flossing frequency, and dental visits. Psychological factors were self-esteem, anxiety, and depression. Self-reported oral health outcomes were single item self-rated oral health and the experience of dental pain. Regression analysis was used to test four conditions for the hypothesis of mediation. RESULTS The results showed that the inequality is present in oral health for some pairs of relationships between socioeconomic status and oral health outcomes. Adjustment for oral health behaviors and psychological factors, individually and simultaneously, led to loss of statistical significance for some pairs of the relationships. However, adjustment for oral health behaviors and psychological factors led to only small changes in the associations between socioeconomic status and self-reported oral health outcomes. CONCLUSIONS This study found a graded oral health inequality, but no strong evidence to support the hypothesis that oral health behaviors and psychological factors mediate oral health inequality for self-reported oral health outcomes.
Strength of urges to smoke as a measure of severity of cigarette dependence: comparison with the Fagerström Test for Nicotine Dependence and its components.

AIMS Measuring the strength of urges to smoke during a normal smoking day among smokers in a culture where smoking is restricted could provide a good measure of the severity of cigarette dependence. An important criterion for a measure of cigarette dependence is how well it predicts failure of attempts to stop smoking. This study compared ratings of Strength of Urges to Smoke (SUTS) with the Fagerström Test of Nicotine Dependence (FTND) and its components, including the Heaviness of Smoking Index (HSI). DESIGN A longitudinal study involving a household survey of a representative sample of adult smokers at baseline and 6-month follow-up by postal questionnaire. SETTING England. PARTICIPANTS A total of 15,740 smokers aged 16 and over underwent the baseline interview; 2593 were followed-up 6 months later, of whom 513 reported having made a quit attempt following the baseline survey but at least 1 month prior to the follow-up. MEASUREMENTS SUTS, FTND, HSI, cigarettes per day, time to first cigarette, age, social grade and gender were measured at baseline. Quit attempts since the baseline assessment and self-reported abstinence were measured at 6-month follow-up. FINDINGS In logistic regressions, all dependence measures predicted success of subsequent quit attempts, but SUTS had the strongest association (beta for SUTS, FTND and HSI: 0.41: P < 0.001, 0.13: P = 0.005, and 0.19: P = 0.003, respectively). In multiple logistic regressions when SUTS was entered as a predictor of abstinence, together with other dependence measures, it remained as the only predictive dependence measure. CONCLUSIONS A simple rating of strength of urges on a normal smoking day appears to be a good predictor of at least short-term quit success in English smokers and as such may be a useful measure of cigarette addiction.
Pluripotent Stem Cells and DNA Damage Response to Ionizing Radiations

Pluripotent stem cells (PSCs) hold great promise in regenerative medicine, disease modeling, functional genomics, toxicological studies and cell-based therapeutics due to their unique characteristics of self-renewal and pluripotency. Novel methods for generation of pluripotent stem cells and their differentiation to the specialized cell types such as neuronal cells, myocardial cells, hepatocytes and beta cells of the pancreas and many other cells of the body are constantly being refined. Pluripotent stem cell derived differentiated cells, including neuronal cells or cardiac cells, are ideal for stem cell transplantation as autologous or allogeneic cells from healthy donors due to their minimal risk of rejection. Radiation-induced DNA damage, ultraviolet light, genotoxic stress and other intrinsic and extrinsic factors triggers a series of biochemical reactions known as DNA damage response. To maintain genomic stability and avoid transmission of mutations into progenitors cells, stem cells have robust DNA damage response signaling, a contrast to somatic cells. Stem cell transplantation may protect against radiation-induced late effects. In particular, this review focuses on differential DNA damage response between stem cells and derived differentiated cells and the possible pathways that determine such differences.
JPE 14-5-25 Co-design of the LCL Filter and Control for Grid-Connected Inverters

In most grid-connected inverters (GCI) with an LCL filter, since the design of both the LCL filter and the controller is done separately, considerable tuning efforts have to be exerted when compared to inverters using an L filter. Consequently, an integrated co-design of the filter and the controller for an LCL-type GCI is proposed in this paper. The control strategy includes only a PI current controller and a proportional grid voltage feed-forward controller. The capacitor is removed from the LCL filer and the design procedure starts from an L-type GCI with a PI current controller. After the PI controller has been settled, the capacitor is added back to the filter. Hence, it introduces a resonance frequency, which is identified based on the crossover frequencies to accommodate the preset PI controller. Using the proposed co-design method, harmonic standards are satisfied and other practical constraints are met. Furthermore, the grid voltage feed-forward control can bring an inherent damping characteristic. In such a way, the good control performance offered by the original L-type GCI and the sharp harmonic attenuation offered by the latter designed LCL filter can be well integrated. Moreover, only the grid current and grid voltage are sensed. Simulation and experimental results verify the feasibility of the proposed design methodology.
Strongyloides stercoralis infection

#### Summary points Strongyloides stercoralis is an intestinal helminth that infects humans through contact with soil containing the larvae. Between 30 and 100 million people are infected worldwide.1 In the United Kingdom, strongyloidiasis is seen predominantly in migrants and returning travellers from endemic areas in the tropics and subtropics. Strongyloidiasis may present with cutaneous or gastrointestinal symptoms but is asymptomatic in over 60% of cases and only indicated by a raised blood eosinophil count.2 Diagnosis is important as the infection may persist for decades.3 Immunosuppressed patients with chronic strongyloidiasis are at high risk of developing strongyloides hyperinfection syndrome, a life threatening complication whereby larval proliferation leads to systemic sepsis and multiorgan failure. If strongyloidiasis is diagnosed early, however, it is easily treatable with oral antihelmintic drugs. In this article we review the epidemiology and common symptoms of strongyloidiasis and strongyloides hyperinfection syndrome, discuss the appropriate investigations, and summarise the evidence on treatment. #### Sources and selection criteria We performed a search of PubMed using the search term “ Strongyloides stercoralis ”, and included English language studies only. There is a paucity of randomised controlled trails investigating the treatment of strongyloides infection, and no Cochrane reviews have been published. Likewise there are no national or globally recognised guidelines for the investigation …
Exercise Stimulates Pgc-1α Transcription in Skeletal Muscle through Activation of the p38 MAPK Pathway*

Peroxisome proliferator-activated receptor γ co-activator 1α (PGC-1α) promotes mitochondrial biogenesis and slow fiber formation in skeletal muscle. We hypothesized that activation of the p38 mitogen-activated protein kinase (MAPK) pathway in response to increased muscle activity stimulated Pgc-1α gene transcription as part of the mechanisms for skeletal muscle adaptation. Here we report that a single bout of voluntary running induced a transient increase of Pgc-1α mRNA expression in mouse plantaris muscle, concurrent with an activation of the p38 MAPK pathway. Activation of the p38 MAPK pathway in cultured C2C12 myocytes stimulated Pgc-1α promoter activity, which could be blocked by the specific inhibitors of p38, SB203580 and SB202190, or a dominant negative p38. Furthermore, the p38-mediated increase in Pgc-1α promoter activity was enhanced by increased expression of the downstream transcription factor ATF2 and completely blocked by ATF2ΔN, a dominant negative ATF2. Skeletal muscle-specific expression of a constitutively active activator of p38, MKK6E, in transgenic mice resulted in enhanced Pgc-1α and cytochrome oxidase IV protein expression in fast-twitch skeletal muscles. These findings suggest that contractile activity-induced activation of the p38 MAPK pathway promotes Pgc-1α gene expression and skeletal muscle adaptation.
Modality and representation in analogy

Abstract Design by analogy is a powerful part of the design process across the wide variety of modalities used by designers such as linguistic descriptions, sketches, and diagrams. We need tools to support people's ability to find and use analogies. A deeper understanding of the cognitive mechanisms underlying design and analogy is a crucial step in developing these tools. This paper presents an experiment that explores the effects of representation within the modality of sketching, the effects of functional models, and the retrieval and use of analogies. We find that the level of abstraction for the representation of prior knowledge and the representation of a current design problem both affect people's ability to retrieve and use analogous solutions. A general semantic description in memory facilitates retrieval of that prior knowledge. The ability to find and use an analogy is also facilitated by having an appropriate functional model of the problem. These studies result in a number of important implications for the development of tools to support design by analogy. Foremost among these implications is the ability to provide multiple representations of design problems by which designers may reason across, where the verb construct in the English language is a preferred mode for these representations.
Stent-Grafting of an Infected Aortoesophageal Fistula following Ingestion of a Fish Bone

The authors have no commercial, proprietary, or financial interest in any products or companies described in this article. However, many heparin limitations may be overcome with this alternative anticoagulant, including avoidance of intraoperative drug level monitoring. The safety profile of bivalirudin, with a trend toward lower bleeding complications and clinical efficacy equal to heparin with a GP IIb/IIIa inhibitor, makes bivalirudin a logical option for peripheral vascular interventions. Our experience with bivalirudin supports its use in either symptomatic or asymptomatic patients undergoing CAS with neuroprotection.
Dietary patterns throughout childhood and associations with nutrient intakes

Abstract Objective To examine how the dietary patterns of children at various time points throughout childhood relate to estimated nutrient intakes. Design FFQ at 3, 4, 7 and 9 years of age were completed by mothers. Dietary patterns were identified cross-sectionally using principal component analysis; ‘processed’, ‘health conscious’ and ‘traditional’ patterns were consistently obtained. Correlations between pattern scores and nutrient intakes and proportions of variance in nutrients explained by the patterns were calculated. Setting Avon Longitudinal Study of Parents and Children (ALSPAC), Bristol, UK. Subjects Children provided data between 3 and 9 years of age (n 8010 to 10 023). Results Dietary patterns explained substantial proportions of the variance of the absolute intake for most nutrients (>25 % at 3 years of age, >40 % other ages). After energy adjustment, protein, fibre, K, Mg, Fe, Zn, folate, thiamin and vitamin B6 continued to be well explained. Strong correlations were observed between the ‘processed’ pattern and macronutrients including energy (r = 0·481–0·619), total fat (r = 0·529–0·662) and total sugar (r = 0·475–0·693). However correlations with most micronutrients were reversed after energy adjustment, suggesting that the ‘processed’ pattern is energy-dense but nutrient-poor. The ‘health conscious’ and ‘traditional’ patterns were strongly positively correlated with protein, fibre and most micronutrients, whether energy adjusted or not. Higher scores on these patterns were associated with a better nutrient profile. Conclusions Dietary patterns explain a reasonable amount of the variation in the nutrient content of diets. Higher scores on the ‘health conscious’ and ‘traditional’ dietary patterns were related to better nutrient profiles; conversely, with higher scores on the ‘processed’ pattern the nutrient profile was poorer.
Sex Difference in the Size of the Neural Song Control Regions in a Dueting Songbird with Similar Song Repertoire Size of Males and Females

Previous studies have suggested a causal relation between sex differences in behavior such as singing and sex differences in the size of brain areas such as the forebrain song control areas of songbirds. In the present study we show that the size of the forebrain vocal control areas nucleus hyperstriatalis ventrale pars caudale (HVC) and nucleus robustus archistriatalis (RA) and its neuron numbers are about twice as large in males as in females of the African dueting bush shrike Laniarius funebris. However, song types are of similar complexity (number of elements per song type, physical properties of elements) in both sexes, and repertoire size does not differ between males and females. Furthermore, in captivity male and female shrikes are able to learn the same song types. This demonstrates for the shrike that sex differences in the size of vocal control areas and in its neuron numbers do not predict the type of sex-typical vocal behavior. This result is supported by a statistical comparison of the sex differences in HVC size, RA size, and song repertoire size of all songbird species studied to date. Sex differences in species in which only the males sing are indeed larger than in species in which the females also sing; in songbird species with singing females, however, the sex differences in HVC and RA volume appear to be independent of the vocal repertoire size of females. The songbird model therefore does not support the notion that sex differences in area size and neuron number explain sex differences in a behavior that occurs in both sexes. Furthermore, in the shrike, neuron soma size is similar in males and females in the song motonucleus hypoglossus pars tracheosyringealis (nXIIts) and in the premotor nucleus RA, but is sexually dimorphic in the higher vocal center HVC. Thus, male and female shrikes produce songs of similar complexity with different neuron phenotypes.