Miracle-dz/UniFAR-FTUs huggingface dataset:
Joint Optimization of Bandwidth for Provider and Delay for User in Software Defined Data Centers

In large-scale Internet applications running on geographically distributed datacenters, such as video streaming, it is important to efficiently allocate requests among datacenters. To the best of our knowledge, existing approaches, however, either solely focus on minimizing total cost for provider, or guaranteeing QoS for end-users. In this paper, we apply the software defined network (SDN) controller to enable the central control of the entire network, and propose a joint optimization model to consider high bandwidth utilization for provider and low delay for users. We present the Nash bargaining solution (NBS) based method to model both requirements of provider’s high bandwidth utilization and end-users’ low delay. Specifically, we formulate the design of request allocation under those requirements as an optimization problem, which is NP-hard. To solve such hard optimization problem, we develop an efficient algorithm blending the advantages of Logarithmic Smoothing technique and the auxiliary variable method. According to the theoretical analysis, we verify the existence and uniqueness of our solution and the convergence of our algorithm. We conduct a large amount of experiments based on real-world workload traces and demonstrate the efficiency of our algorithm compared to both greedy and locality algorithms.
High Burden of Unrecognized Atrial Fibrillation in Rural India: An Innovative Community-Based Cross-Sectional Screening Program

Background Atrial fibrillation, the world’s most common arrhythmia, is a leading risk factor for stroke, a disease striking nearly 1.6 million Indians annually. Early detection and management of atrial fibrillation is a promising opportunity to prevent stroke but widespread screening programs in limited resource settings using conventional methods is difficult and costly. Objective The objective of this study is to screen people for atrial fibrillation in rural western India using a US Food and Drug Administration-approved single-lead electrocardiography device, Alivecor. Methods Residents from 6 villages in Anand District, Gujarat, India, comprised the base population. After obtaining informed consent, a team of trained research coordinators and community health workers enrolled a total of 354 participants aged 50 years and older and screened them at their residences using Alivecor for 2 minutes on 5 consecutive days over a period of 6 weeks beginning June, 2015. Results Almost two-thirds of study participants were 55 years or older, nearly half were female, one-third did not receive any formal education, and more than one-half were from households earning less than US $2 per day. Twelve participants screened positive for atrial fibrillation yielding a sample prevalence of 5.1% (95% CI 2.7-8.7). Only one participant had persistent atrial fibrillation throughout all of the screenings, and 9 screened positive only once. Conclusions Our study suggests a prevalence of atrial fibrillation in this Indian region (5.1%) that is markedly higher than has been previously reported in India and similar to the prevalence estimates reported in studies of persons from North America and Europe. Historically low reported burden of atrial fibrillation among individuals from low and middle-income countries may be due to a lack of routine screening. Mobile technologies may help overcome resource limitations for atrial fibrillation screening in underserved and low-resource settings.
Developmental expression of mucin genes in the human gastrointestinal system

Background and aims—Mucin glycoproteins play a key role in the normal function of the epithelium lining the gastrointestinal tract. The expression of mucin genes, MUC 3, 4, 5AC, 5B, 6, 7, and 8 in human fetal tissues was examined to establish the localisation and age of onset of expression of each mucin gene during human development. Methods—Mucin gene expression was assayed by mRNA in situ hybridisation. Results—Expression of MUC3 was detected in the small intestine and colon from 13 weeks gestation onwards and at low levels in the main pancreatic duct at 13 weeks only. MUC4 expression was seen at a low level in the colonic epithelium from 13 weeks of gestation but not elsewhere in the gastrointestinal tract. MUC5AC mRNA was detected in the colon at 17 weeks and at high levels in the stomach at 23 weeks. MUC6transcripts were evident in the pancreatic ducts from 13 weeks of gestation and at high levels in the stomach at 23 weeks.MUC5B, MUC7, and MUC8transcripts were not detected. Conclusions—Mucin genes are expressed from the early mid-trimester of gestation in the developing human fetal gastrointestinal tract.
AML at older age: age-related gene expression profiles reveal a paradoxical down-regulation of p16INK4A mRNA with prognostic significance.

Acute myeloid leukemia (AML) has a different clinical and biologic behavior in patients at older age. To gain further insight into the molecular differences, we examined a cohort of 525 adults to compare gene expression profiles of the one-third of youngest cases (n = 175; median age 31 years) with the one-third of oldest cases (n = 175; median age 59 years). This analysis revealed that 477 probe sets were up-regulated and 492 probe sets were down-regulated with increasing age at the significance level of P < . 00001. After validation with 2 independent AML cohorts, the 969 differentially regulated probe sets on aging could be pointed to 41 probe sets, including the tumor-suppressor gene CDKN2A (encoding p16(INK4A)). In contrast to the induced p16(INK4A) expression that is associated with physiologic aging, p16(INK4A) is down-regulated in AML samples of patients with increasing age. However, this was only noticed in the intermediate- and unfavorable-risk group and not in the favorable-risk group and the molecularly defined subset "NPM1 mutant without FLT3-ITD. " Multivariate analysis revealed p16(INK4A), besides cytogenetic risk groups, as an independent prognostic parameter for overall survival in older patients. We conclude that, in addition to altered clinical and biologic characteristics, AML presenting at older age shows different gene expression profiles.
When culture and learning styles matter: A Canadian university with Middle-Eastern students

Transnational branch campuses of universities are a growing phenomenon, particularly in the Middle-East. The cultures of home institutions and host countries are often foreign to each other. The result is a cultural and learning style gap between faculty and students impacting students’ learning and teachers’ effectiveness. A pilot study of the University of Calgary, at its Canadian branch campus located in Qatar, looks at the differences in learning styles between faculty who are predominantly from Canada and students predominantly from Qatar.
Representations of Non-Negative Polynomials, Degree Bounds and Applications to Optimization

Abstract Natural sufficient conditions for a polynomial to have a local minimum at a point are considered. These conditions tend to hold with probability 1. It is shown that polynomials satisfying these conditions at each minimum point have nice presentations in terms of sums of squares. Applications are given to optimization on a compact set and also to global optimization. In many cases, there are degree bounds for such presentations. These bounds are of theoretical interest, but they appear to be too large to be of much practical use at present. In the final section, other more concrete degree bounds are obtained which ensure at least that the feasible set of solutions is not empty.
Factors associated with psychotic relapse in patients with schizophrenia in a Pakistani cohort

Despite a large body of research evaluating factors associated with the relapse of psychosis in schizophrenia, no studies in Pakistan have been undertaken to date to identify any such factors, including specific cultural factors pertinent to Pakistan. Semistructured interviews and psychometric measures were undertaken with 60 patients diagnosed with schizophrenia (49 male and 11 female) and their caregivers at four psychiatric hospitals in the Peshawar region in Pakistan. Factors significantly associated with psychotic relapse included treatment non-adherence, comorbid active psychiatric illnesses, poor social support, and high expressed emotion in living environments (P < 0.05). The attribution of symptoms to social and cultural values (97%) and a poor knowledge of psychosis by family members (88%) was also prevalent. In addition to many well-documented factors associated with psychotic relapse, beliefs in social and cultural myths and values were found to be an important, and perhaps treatable, factor associated with relapse of psychosis in Pakistan. The provision of evidence-based psychotherapeutic interventions, such as behaviour and family therapy and cognitive behaviour therapy for psychosis, could potentially ameliorate the relapse rate of psychosis in Pakistan.
Laughing, Tickling, and the Evolution of Speech and Self

Laughter is an instinctive, contagious, stereotyped, unconsciously controlled, social play vocalization that is unusual in solitary settings. Laughter punctuates speech and is not typically humor related, speakers often laugh more often than their audience, and male speakers are the best laugh getters. Laughter evolved from the labored breathing of physical play, with the characteristic “pant-pant” laugh of chimpanzees and derivative “ha-ha” of humans signaling (“ritualizing”) its rowdy origin. Laughter reveals that breath control is why humans can speak and chimpanzees cannot. The evolution of bipedality in human ancestors freed the thorax of its support role in quadrupedal locomotion, a critical step in uncoupling breathing from running, providing humans with the flexible breath control necessary for speech and our characteristic laugh. Tickle, an ancient laughter stimulus, is a means of communication between preverbal infants and mothers, and between friends, family, and lovers. Because you cannot tickle yourself, tickle involves a neurological self/nonself discrimination, providing the most primitive social scenario.
Improving outcomes after esophagectomy: The impact of operative volume

Once considered an uncommon malignancy, primary esophageal adenocarcinoma has increased steadily in incidence over the past three decades. Despite advances in multimodality therapy, the prognosis for this tumor is generally poor. Surgical resection and reconstruction of the upper gastrointestinal tract is the current standard of care for localized esophageal cancer, but despite advances in perioperative care, still remains a relatively high‐risk surgical procedure. Increasing numbers of reports published over the past decade have documented a clear volume‐outcome relationship for several complex surgical procedures, and in particular for esophagectomy. The clinical implications of this association are reviewed in this section. J. Surg. Oncol. 2005;92:262–266. © 2005 Wiley‐Liss, Inc.
On the Digital Playing Field

In the following article, the author explores the notion of playing computer games as sports by sketching out the labors and sensations of Counter-Strike teams playing at pro/am e-sports local area network (LAN) tournaments. How players are engaged physically in practice and play is described in this qualitative study through the core themes of movement, haptic engagement, and the balanced body. Furthermore, the research describes how technologies in play are laboring actors too; the players and technologies in this study are rendered as networked, extended, and acting in and on the same fields of play. In asking is there a “sport” in e-sports, this study questions the legitimacy of a traditional sports ontology and simultaneously tackles the notion of engagement with computer game play as a legitimate sporting endeavor.
The cardiac output in patients with cirrhosis of the liver and tense ascites with observations on the effect of paracentesis.

Previous studies in this laboratory (1) have indicated that the cardiac output may be elevated in patients with Laennec's cirrhosis. The question arose as to what role distention of the abdomen by ascites might play in determining the level of systemic blood flow. In the previously reported patients, elevation of cardiac output did not appear to be related to the presence or degree of ascites, but this aspect of the problem required further investigation. Few studies of the effect of ascites on cardiac output in man have come to our attention. Resnik, Friedman, and Harrison (2) estimated cardiac output in patients with congestive heart failure by means of the acetylene method and noted slight decreases during the accumulation of ascites in four patients. Six hours after paracentesis, per
Design and implementation of a music composition application using speech recognition

This paper describes speech recognition as a research area, by studying its application to a non trivial problem such as music composition. The design and implementation process of TamTam Listens, a voice-user interface for music composition, is described. This application was developed using open-source tools, like the speech recognition engine PocketSphinx, the acoustic models provided by Voxforge and the Sugar learning platform. Finally, the results of a usability test performed with TamTam Listens are exposed. These results allow drawing conclusions about speech recognition applicability to user interfaces, and offering recomendations for their design and implementation.
Introgressed Animal Schistosomes Schistosoma curassoni and S. bovis Naturally Infecting Humans

net) with the maximum-likelihood algorithm and a bootstrap of 1,000 replicates, we constructed a phylogenetic tree (online Technical Appendix Figure). All 8 sequences clustered within subtype 4d of HEV. The sequences were similar to each other (95.5%–99.8% similarity in nucleotide sequence) and similar to sequences reported for other cattle (83.3%–85.3%; online Technical Appendix Figure). Moreover, these sequences shared 96.1%–96.6% similarity with a human HEV strain (GenBank accession no. KC163335) from the Yantai Prefecture in 2012 and 95.7%–97.9% similarity with a swine strain (GenBank accession no. KF176351) isolated in Shandong Province the same year. Our data strongly indicate that HEV infection occurs in yellow cattle and that they could also play a role as a reservoir of HEV. Because these animals serve mainly as a source of food, consumption of undercooked meat from yellow cattle, similar to pork, might also contribute to the transmission of HEV to humans. Additionally, we also detected HEV RNA in 8 of 70 sheep (online Technical Appendix Table 2). Eight sequences from yellow cattle had 95.1%–99.8% nt homology with 8 sheep-derived HEV strains, possibly because mixed raising of domestic livestock is popular in this region. Our finding of high sequence similarity between yellow cattle, sheep, swine, and human populations suggests a complicated interspecies transmission of HEV occurred in this province. Further studies are required to evaluate the contribution of the yellow cattle reservoir to human HEV infection.
3D object detection and pose estimation from depth image for robotic bin picking

In this paper, we present a system for automatic object detection and pose estimation from a single depth map containing multiple objects for bin-picking applications. The proposed object detection algorithm is based on matching the keypoints extracted from the depth image by using the RANSAC algorithm with the spin image descriptor. In the proposed system, we combine the keypoint detection and the RANSAC algorithm to detect the objects, followed by the ICP algorithm to refine the 3D pose estimation. In addition, we implement the proposed algorithm on the GPGPU platform to speed-up the computation. Experimental results on simulated depth data are shown to demonstrate the proposed system.
Epitopes from two soybean glycinin subunits are antigenic in pigs.

BACKGROUND Glycinin is a seed storage protein in soybean (Glycine max) that is allergenic in pigs. Glycinin is a hexamer composed of subunits consisting of basic and acidic portions joined by disulfide bridges. There are five glycinin subunit isoforms designated Gy1-Gy5. The purpose of this study is to identify epitopes from selected glycinin subunits that are antigenic in pigs. RESULTS Twenty-seven out of 30 pigs had antibodies against glycinin in their sera. Ten of these sera had immunoglobulin G (IgG) against the Gy4 (A5A4B3) or Gy1 (A1aBx) subunit. Three sera recognised overlapping regions between the two subunits tested, though no serum stained both A5A4B3 and A1aBx. Two sera stained a highly conserved region between A5A4B3 and A1aBx, though again neither serum stained both peptides. The basic part of the A1aBx subunit was not recognised by any of the sera tested even though immunoblot data indicated that the basic and acidic subunits of glycinin are nearly equally antigenic. CONCLUSION Two antigenic regions of A5A4B3 and A1aBx were identified that bound antibodies in half of the sera that reacted with these two proteins. Half of the sera reacted with unique regions of A5A4B3 and A1aBx. The failure of the basic portion of A1aBx to bind pig antibodies may indicate that it is less antigenic than the basic portion of A5A4B3 and other glycinin subunits.
Apoptosis of thymocytes related to cytokine expression in experimental classical swine fever.

Atrophy of the thymic cortex and loss of thymocytes were studied in 32 pigs inoculated with the virulent strain "Alfort" of classical swine fever (CSF) virus and killed at intervals from 2 to 15 days after infection. Immunohistochemical, ultrastructural, ELISA and TUNEL methods were used. The results suggested that direct action of CSF virus on thymocytes played no more than a minor role. The massive lymphoid depletion observed in the thymus, may, however, have been associated with the numerical increase in monocytes-macrophages in this organ, and their secretory activation, leading to synthesis and release of tumour necrosis factor (TNF)-alpha, interleukin (IL)-1alpha and C1q complement component as main chemical mediators, and IL-1beta and IL-6 as minor mediators. These cytokines (TNF-alpha and IL-1alpha) may have played a role in the apoptosis of thymocytes, demonstrated by TUNEL and ultrastructural methods. The pathogenetic mechanism outlined may contribute to the lymphoid depletion observed in others organs in CSF and may explain the lymphopenia characteristic of the disease.
SCALE: A Low-Complexity Distributed Protocol for Spectrum Balancing in Multiuser DSL Networks

Dynamic spectrum management of digital subscriber lines (DSLs) has the potential to dramatically increase the capacity of the aging last-mile copper access network. This paper takes an important step toward fulfilling this potential through power spectrum balancing. We derive a novel algorithm called SCALE, that provides a significant performance improvement over the existing iterative water-filling (IWF) algorithm in multiuser DSL networks, doing so with comparable low complexity. The algorithm is easily distributed through measurement and limited message passing with the use of a spectrum management center. We outline how overhead can be managed, and show that in the limit of zero message-passing, performance reduces to IWF.
‘I'm American, not Japanese!’: the struggle for racial citizenship among later-generation Japanese Americans

Abstract As one of the oldest Asian American groups in the USA, most Japanese Americans are of the third and fourth generations and have become well integrated in mainstream American society. However, they are still racialized as foreigners simply because of their Asian appearance. Their Asian phenotype continues to have a foreigner connotation because of large-scale immigration from Asia and an American national identity that is racially defined as white. This paper analyses how later-generation Japanese Americans are racialized as outsiders in their daily interaction with mainstream Americans, which is often accompanied by essentialized assumptions that they are also culturally foreign. In response, they engage in everyday struggles for racial citizenship by demanding inclusion in the national community as Americans despite their racial differences. It is uncertain whether such attempts to contest their racialization will cause current mono-racial notions of American identity to be reconsidered in more inclusive and multiracial ways.
Antimicrobial activity of naphthoquinones extracted from Arnebia nobilis

Arnebia nobilis Rech. f. , a natural source of red dye has tradition ally been used as a food colourant, in cosmetic formulations and pharmaceutical preparations. In this study, the extracted dye and separated components o f A. nobilis have been studied for their antibacterial activity. The extracted dye and its major component, alkannin β, β- dimethylacrylate has also been evaluated as an anti bacterial finish on various textile substrates viz. nylon, polyester, silk, wool, cotto n and acrylic. The dye and its components showed excellent antimicrobial activity against both S. aureus and E. coli . Amongst the fabrics dyed with 5% dye, wool, silk and acrylic showed 100% activity against both the microbes. Polyester showe d 100% activity against S. aureus and ~ 80% activity against E. coli . Nylon and cotton showed no antimicrobial activity . Durability of antimicrobial activity to laundering and to light is also discussed.
Education journals: Two decades of change and implications for the field

The authors sought to systematically examine patterns of change over time, as well as current variations, in educational journal specifications and publishing, including higher education. The 100 journals in this sample included research and practitioner venues across a range of subdomains and specializations. The authors gathered data for 3 points in time, at 10‐year intervals during a 20‐year period, from 1989–2009. They examined the following in detail: journal profiles for publishing characteristics, submission specifications for manuscript parameters, and full‐text published manuscripts for compliance with specifications. All were analyzed as point‐in‐time comparisons as well as trajectories of change over time. Journal profiles demonstrated patterns of increased centralization and digitization, inclusiveness of readership, increased frequency of issues, and increased length of articles. Key findings for manuscript parameter trends included increased specificity of detail, range of manuscript types and research designs accepted, and average manuscript length. In addition, journals have more explicitly specified elements previously left implicit, such as professional and ethical standards. Criteria for submission procedures and manuscript quality are consistent with university faculty performance standards for productivity and technological advancement. Findings carry implications for publishing, journal management, faculty work, and performance evaluation.