Miracle-dz/UniFAR-FTUs huggingface dataset:
Molybdenum(VI) complexes of N, N′-bis isatin diamine Schiff base: Synthesis and characterization

Schiff base ligand of N, N′-bis isatin diamine was synthesized from various diamine and isatin through condensation reaction in 1:2 molar ratio. Mo(VI) complexes of isatin-diamines were synthesized by the reaction between the sodium molybdate dehydrate and N,N' bis isatin diamines with the reflux method. The synthesized ligand and complexes were characterized using spectroscopic techniques. The FT-IR band of azomethine group at 1600- 1610 cm-1 indicated the formation of the ligand. The UV-vis spectra clearly indicated that the prepared complex is a genuine Mo(VI) with d0 electronic configuration. The formation of a coordination bond was revealed by the downfield chemical shift of the complex in the NMR data as compared to the ligand. The UV results were corroborated by molar conductance data, which demonstrated their non-electrolytic character. The experimental evidence primarily supported the synthesis of both ligands and corresponding Mo(VI) complexes. Bangladesh J. Sci. Ind. Res. 58(4), 201-208, 2023
Dynamics in the Predictability of Credit Default Swap Spreads of EU Companies

The COVID-19 pandemic affected financial instruments and markets all around the world. Credit default swap contracts of EU companies were analysed in this paper. The data consist of daily credit default swap spreads and market capitalisations of EU companies, exchange rates, LIBOR rates, bond yields, and commodity futures prices from January 2010 to February 2022. The dynamics in the performance of forecasting models for credit default swap spreads before and after the declaration of the COVID-19 pandemic were measured by relative error metrics, i.e., relative root mean squared error, relative mean absolute error, and relative mean absolute percentage error. The results show a small drop in the performance right after the declaration of the COVID-19 pandemic that is mitigated by strong performance in the rest of the year, followed by a significant drop in the performance in the second year of the pandemic.
Artificial achievements

State-of-the-art machine learning systems now routinely exceed benchmarks once thought beyond the ken of artificial intelligence (AI). Often these systems accomplish tasks through novel, insightful processes that remain inscrutable to even their human designers. Taking AlphaGo’s 2016 victory over Lee Sedol as a case study, this paper argues that such accomplishments manifest the essential features of achievements as laid out in Bradford’s 2015 book Achievement. Achievements like these are directly attributable to AI systems themselves. They are artificial achievements. This opens the door to a challenge that calls out for further inquiry. Since Bradford grounds the intrinsic value of achievements in the exercise of distinctively human perfectionist capacities, the existence of artificial achievements raises the possibility that some achievements might be valueless.
An Overview of Visual Sound Synthesis Generation Tasks Based on Deep Learning Networks

Visual sound synthesis (which refers to the process of recreating, as realistically as possible, the sound produced by the movements and actions of objects within a video, given specific conditions such as video content and accompanying text) is an important part of the composition of high-quality films at present. Most traditional methods of sound synthesis are based on the artificial creation of simulated props for sound effects synthesis, which is achieved by using various existing props and constructed scenes. However, traditional methods cannot meet specific conditions for sound effect synthesis and require large amounts of participant, material resources and time. It can take nearly ten hours to simulate realistic sound effects in a minute-long video. In this paper, we systematically summarize and consolidate current advances in deep learning in the field of visual sound synthesis, based on existing related papers. We focus on the exploration and development history of deep learning models for the task of visual sound synthesis, and classify detailed research methods and related dataset information based on their development characteristics. By analyzing the technical differences among various model approaches, we can summarize potential research directions in the field, thereby further promoting the rapid development and practical implementation of deep learning models in the video domain.
Saturn as the "Sun of Night" in Ancient Near Eastern tradition

This article tackles two issues in the "proto-astronomical" conception of the planet Saturn, first attested in Mesopatamia and followed by the Greeks and Hindus: the long-standing problem of Saturn's baffling association with the Sun: and why Saturn was deemed to be "black". After an extensive consideration of explanations offered from the 5th century to the 21st. as well as some new "thought experiments", we suggest that Saturn's connection with the Sun had its roots in the observations that Saturn's course appears to be the steadiest one among the planets and that its synodic period _of all the planets_ most closely resembles the lenght of the solar year. For the black colour attributed to Saturn we propose a solution which is partly lexical and partly observational (due to atmospheric effects). Finally, some thoughts are offered on the question why in Hellenistic times some considered the "mock sun" Phaethon of Greek myth to have been Saturn
Technical Factors Influencing the Health Information System in Kosova

Background: Health information systems (HIS) are considered a vital tool to strengthen Low- and Middle-Income Countries’ (LMIC) health systems. Unfortunately, little is known about the technical factors of HIS in LMIC. Objective: This study aimed to make an empirical contribution, using the case of Kosova to find out about HIS development, trying to identify dysfunctional areas and opportunities for improvement. Methods: Technical factors of the PRISM framework were analyzed via document analysis, and semi-structured interviews were held with 15 respondents from the Ministry of Health, the National Institute of Public Health of Kosova, and the Hospital Clinical University Services of Kosova. Interviews were transcribed and coded deductively, using the defined theoretical framework to guide the content analysis. Results: The results indicate that MoH considered technical factors while developing HIS in Kosova. Nevertheless, HIS fulfills only some of the essential functions. Barriers to efficient HIS among technical factors are lengthy, time-consuming manual HIS forms, inadequate data from HIS forms for NIPHK analysis, difficulties when changing software and HIS economic operators, and the complexity of HIS functioning. Conclusion: Kosova still faces technical difficulties with an efficient and sustainable HIS system. Complex processes of extensive efforts have yet to produce the desired results, which prevent evidence-based health analysis and informed decision-making in Kosovar healthcare. More research is needed into organizational and behavioral factors influencing HIS efficiency in LMIC.
Assessment of heavy metals contamination of agricultural soils using pollution indicators in Thi-Qar governorate, Southern Iraq

This study aims to assess the levels of contamination of agricultural soils with heavy elements (cobalt, copper, iron, nickel, cadmium, and lead) in three regions in Thi-Qar Governorate, Southern Iraq. These three regions are Al-Gharraf, Al-Islah, and Al-Batha. The study was done by using the pollution indicators, which are geographical pollution index (Igeo), contamination degree (Cd), contamination factor (Cf), pollution load index (PLI), potential ecological risk factor (Er), and finally, risk index (RI). From each region, four soil samples were collected from holes 25 cm deep, separated by a distance of 500 meters. After the digestion process of the samples, the concentrations of the studied elements were measured by flam atomic absorption spectrometer (FAAS). The results showed that the average heavy metal concentrations for all samples were (365.810, 96.424, 41.36, 11.919, 5.194 and 0.352 mg/kg). They were in the following order Fe > Ni > Cu >Co > Pb > Cd, respectively. The concentrations of heavy metals in the study areas were all within the limits allowed by the World Health Organization (WHO) except for 8.3% of the studied areas that were beyond the permissible limits for cadmium only. The reason for the increase in cadmium concentrations in some areas could be due to sewage, industrial emissions and agricultural practices. According to the Igeo values, the levels of minerals studied for the three regions followed the following order Cd > Cu > Co > Pb > N i> Fe.
Studying of some proteins levels and enzymes activities in the amniotic fluid for pregnant associated with premature birth . 1

Highlights  This study evaluates the apical leakage and the adaptability of two silicone-based root canal sealers.  Shed the light on the importance of sealing ability of root canal filling material.  Clearing technique and horizontal technique to evaluate the adaptability and presence of void in root canal filling.  The tested silicon-based root canal sealers could not completely prevent dye penetration.
Effectiveness of a Low-Dose Mindfulness Intervention for College Students: Does Major Play a Role?

This study addressed the elevated rates of distress among college students and emphasized the potential benefits of preventive programs through examining the effectiveness of a low-dose mindfulness intervention implemented throughout a college semester. The Mindful Ambassador Program (MAP) was introduced as a universal intervention integrated into classroom instruction to large classes in the College of Education with a sample of 105 participants from diverse majors. Measures of well-being, depression, anxiety, and stress were administered at the beginning and end of the semester. Participants were categorized into three groups based on their majors. The effectiveness of the intervention was analyzed using a two-tailed t -test. The findings indicated only a significant change in scores before and after the intervention for anxiety. The levels of depression and anxiety scores were consistently lower for the Psychology students compared to those in other majors. The study acknowledged limitations, including the need to consider confounding variables and the absence of specific stressor data.
Patient and public involvement in international research: Perspectives of a team of researchers from six countries on collaborating with people with lived experiences of dementia and end‐of‐life

Abstract Background Patient and public involvement (PPI) is a critical priority in research, policy, academia and advocacy organizations. PPI in dementia research is gaining momentum. However, these efforts are missing in international projects aimed at those living with advanced dementia in long‐term care (LTC) homes. Additional complexities can arise in enacting PPI within the context of integration of a palliative approach to care and experiences around end‐of‐life in (EOL) dementia. The mySupport study involved implementing the Family Carer Decision Support (FCDS) intervention for care partners of those living with advanced dementia in LTC in six countries. Research Design and Objective An interpretive description study was conducted to explore the perspectives of international researchers from six countries on engaging people with lived experiences of dementia and EOL care in research processes. The findings from this study informed the development of a PPI strategy and a subsequent toolkit for the FCDS intervention. Findings Thirty‐eight interviews were completed with project researchers: 12 from the United Kingdom, 8 from Canada, 7 from Ireland, 4 each from Italy and The Netherlands and 3 from the Czech Republic. Four broad themes describe international researchers' perspectives on advancing methods of engagement for people with lived experiences of dementia and EOL in international PPI activities: (1) Groundwork to engage in research; (2) planning for research activities is key; (3) focus on meaningful engagement and (4) having foresight for practical issues shaping PPI. Discussion and Implications International projects that involve PPI can present many sources of challenges. The findings in this study highlight important considerations for foundational work for incorporating PPI in international projects. Learning from world leaders and those with lived experiences in various regions can be insightful and help share tools and resources. Patient or Public Contribution PPI was envisioned as a critical part of conducting the mySupport study. The findings from this study informed the development of a PPI strategy and an international Strategic Guiding Council that included family carers of those living with advanced dementia in LTC homes in six countries. This manuscript focused on the perspectives of researchers on their engagement with people with lived experiences of dementia and EOL. The perspectives of persons with lived experiences on engaging in the mySupport research study will be reported in a forthcoming manuscript.
The BRCA2 R2645G variant increases DNA binding and induces hyper-recombination.

BRCA2 tumor suppressor protein ensures genome integrity by mediating DNA repair via homologous recombination (HR). This function is executed in part by its canonical DNA binding domain located at the C-terminus (BRCA2CTD), the only folded domain of the protein. Most germline pathogenic missense variants are located in this highly conserved region which binds to single-stranded DNA (ssDNA) and to the acidic protein DSS1. These interactions are essential for the HR function of BRCA2. Here, we report that the variant R2645G, identified in breast cancer and located at the DSS1 interface, unexpectedly increases the ssDNA binding activity of BRCA2CTDin vitro. Human cells expressing this variant display a hyper-recombination phenotype, chromosomal instability in the form of chromatid gaps when exposed to DNA damage, and increased PARP inhibitor sensitivity. In mouse embryonic stem cells (mES), this variant alters viability and confers sensitivity to cisplatin and Mitomycin C. These results suggest that BRCA2 interaction with ssDNA needs to be tightly regulated to limit HR and prevent chromosomal instability and we propose that this control mechanism involves DSS1. Given that several missense variants located within this region have been identified in breast cancer patients, these findings might have clinical implications for carriers.
A framework to analyze knowledge management system adoption through the lens of organizational culture

Abstract Although, the knowledge management (KM)-culture research has helped to validate the importance of cultural values for companies' KM initiatives and provided insights into some important values, it still lacks frameworks and analysis outlining how specific types of cultural values might relate to Knowledge Management system (KMS) adoption and subsequent outcomes. In this paper, we provide a three-dimensional framework to help managers articulate how culture affects their unit's ability to create, transfer, and apply knowledge through KMS use. To illustrate the application of the framework, we also present an exploratory case study we have performed in an international organization in the area of development assistance and capacity development.
Significance of Preoperative Modified Nutritional Risk Index in Patients With Gastric Cancer After Curative Resection

Background/Aim: A new modified nutritional risk index (mNRI), calculated using serum albumin (g/l)+body mass index (BMI) [weight (kg_/height2 (m2)], is a good predictor of postoperative complications and cancer survival. However, no study has used this index in patients with gastric cancer (GC). Therefore, we aimed to investigate the clinical significance of the preoperative mNRI values in patients with GC who underwent curative resection. Patients and Methods: We examined 449 patients who underwent curative resection for GC at Kanagawa Cancer Center between 2013 and 2017. The mNRI cutoff value obtained using a receiver operating characteristic analysis was 23.31. Patients were divided into high and low mNRI groups according to the cutoff value, and the clinicopathological characteristics and outcomes were compared between the two groups. Results: In terms of clinicopathological characteristics, the high mNRI group had a higher proportion of men, higher BMI, and a higher proportion of patients with American Society of Anesthesiologists physical status class 2/3 compared with the low mNRI group; the low mNRI group had significantly worse 5-year recurrence-free survival (RFS) and overall survival (OS) than the high mNRI group (OS, p=0.005) (OS, p=0.006; RFS, p=0.018) did. In the multivariate analysis, a low mNRI was an independent predictor of OS (p=0.006) and RFS (p=0.013). Conclusion: Preoperative mNRI may be a useful recurrence and prognostic biomarker in patients with GC who have undergone curative resection.
Association of Geriatric Nutritional Risk Index With Immune Checkpoint Inhibitor Treatment Duration and Adverse Events in Lung Cancer

Background/Aim: Compared to conventional cytotoxic anticancer agent-based therapy, treatment with immune checkpoint inhibitors (ICI) significantly prolongs overall survival. The Geriatric Nutritional Risk Index (GNRI) has been used as a new prognostic indicator in cancer. As nutritional status is associated with prognosis and indicates treatment response, we investigated the effect of the pretreatment GNRI on the (1) occurrence of ICI-induced immune-related adverse events (ir-AE) and (2) association with time to treatment failure (TTF) in ICI monotherapy for lung cancer. Patients and Methods: In this study, 127 patients with lung cancer who were treated with ICI monotherapy were retrospectively enrolled. Based on a cutoff value of 92 for the GNRI, we investigated intergroup differences in the occurrence of adverse events and their association with TTF in the High-GNRI (≥92) and Low-GNRI (<92) groups. For intergroup comparisons, we used the Student’s t-test, Welch’s t-test, Fisher’s direct probability test, and Mann–Whitney’s U-test, and factors with p<0.05 in the intergroup comparison were extracted as explanatory variables. Results: Based on the pretreatment GNRI, the median TTF was 5.1 months (95%CI=2.4-7.9 months) in the High-GNRI group and 2.3 months (95%CI=1.6-3.1 months) in the Low-GNRI group, with the High-GNRI group having a significantly longer TTF (p<0.01). The incidence of skin rash (p=0.0129) and pruritus (p<0.01) was significantly higher in the High-GNRI group. Conclusion: Pretreatment GNRI influences the continuation of ICI monotherapy. The High-GNRI group demonstrated a significantly higher frequency of skin lesions, which may have influenced the prolongation of TTF.
Long-term administration of probiotics prevents gastrointestinal mucosal barrier dysfunction in septic mice partly by upregulating the 5-HT degradation pathway

Abstract Sepsis can impair gastrointestinal (GI) barrier integrity. Oral probiotics (PT) can maintain the balance of GI microflora and improve GI function. 5-Hydroxytryptamine (5-HT) is a key promoter of GI injury caused by sepsis. However, the mechanism by which PT attenuates sepsis by regulating 5-HT is not fully understood. In this study, C57BL6 mice were intragastric administrated with normal saline (NC) or PT once a day for 4 weeks before cecal ligation and puncture (CLP). Compared with NC-CLP mice, PT-CLP mice had lower clinical score, higher body temperature. The survival rate of PT-CLP mice was significantly improved. The levels of inflammatory cytokines and 5-HT were obviously decreased in PT-CLP mice, and GI peristalsis and barrier function were enhanced. Moreover, sepsis downregulated the expression of tight junction proteins, while PT pretreatment could maintain them at the level of sham operation group. Furthermore, PT pretreatment increased the expression of serotonin transporter and monoamine oxidase A. PT administration could inhibit NF-κB activity, and activate ERK activity. In conclusion, long-term supplementation of PT before CLP can prevent sepsis-induced GI mucosal barrier dysfunction in mice, which may be partially mediated by upregulating the 5-HT degradation pathway via activating ERK signaling.
Sorry About the Connection: Client-Reported Telehealth Technology Competency and Difficulties

Abstract The growing body of research on telehealth services provides evidence of the efficacy of services and the possibility for greater accessibility of counseling services for hard-to-reach clients. However, less is known how clients think about the process of telehealth for mental health services. This study focused on two dimensions of client perception: telehealth difficulties and telehealth technology competency. This study examined the factor structure of two client-reported new measures, the Telehealth Difficulties Scale and the Telehealth Technology Competency Scale, through exploratory factor analyses. Results found that both measures had a one-factor structure with a high degree of reliability. Implications for these results are discussed, and future directions are given.
Determinants of entrepreneurial business relationship success.

The business development literature illustrates the importance of relationships on achieving targets and ensuring the sustainability of enterprises. In this paper the sphere of franchising which is essentially an entrepreneurial business is used to link measures of business relationships in the domains of trust, credibility, commitment, integrity, confidence and trust to the success of the business. It is found that irrespective of size and age of the franchise and business sector of operation that these relationships are important determinants of success. Although they do not act directly to enhance the prospect of success it is via their interactions that success arises.
The role of well vulnerability mapping in quantifying the impact of well contamination

Well vulnerability expresses the impact due to a well becoming contaminated. The relevant factors which define this impact are the maximum concentration expected at a well due to a nearby source of contamination, the time taken to reach this maximum, and the time taken to reach some critical drinking water limit. These factors, which depend on the physical characteristics of the aquifer system, can be determined by means of transport modelling and are presented in the form of vulnerability maps. These maps provide better quantitative information and more insight into the problem of well contamination than conventional capture zone delineations alone. The methodology for determining well vulnerability is demonstrated.