Miracle-dz/UniFAR-FTUs huggingface dataset:
Bi2Te3/Bi2Se3/Bi2S3 Cascade Heterostructure for Fast‐Response and High‐Photoresponsivity Photodetector and High‐Efficiency Water Splitting with a Small Bias Voltage

Large‐scale multi‐heterostructure and optimal band alignment are significantly challenging but vital for photoelectrochemical (PEC)‐type photodetector and water splitting. Herein, the centimeter‐scale bismuth chalcogenides‐based cascade heterostructure is successfully synthesized by a sequential vapor phase deposition method. The multi‐staggered band alignment of Bi2Te3/Bi2Se3/Bi2S3 is optimized and verified by X‐ray photoelectron spectroscopy. The PEC photodetectors based on these cascade heterostructures demonstrate the highest photoresponsivity (103 mA W−1 at −0.1 V and 3.5 mAW−1 at 0 V under 475 nm light excitation) among the previous reports based on two‐dimensional materials and related heterostructures. Furthermore, the photodetectors display a fast response (≈8 ms), a high detectivity (8.96 × 109 Jones), a high external quantum efficiency (26.17%), and a high incident photon‐to‐current efficiency (27.04%) at 475 nm. Due to the rapid charge transport and efficient light absorption, the Bi2Te3/Bi2Se3/Bi2S3 cascade heterostructure demonstrates a highly efficient hydrogen production rate (≈0.416 mmol cm−2 h−1 and ≈14.320 µmol cm−2 h−1 with or without sacrificial agent, respectively), which is far superior to those of pure bismuth chalcogenides and its type‐II heterostructures. The large‐scale cascade heterostructure offers an innovative method to improve the performance of optoelectronic devices in the future.
Lack of Knowledge and Misperceptions on Photoprotection among Brazilian Youngsters

Daily photoprotection (PhP) is essential in preventing harmful effects from solar ultraviolet radiation (UVR) exposure. For that reason, we interviewed students aged from 4 to 20 years old about their knowledge on sun exposure and PhP habits. Age, sex, family income, and skin phototype were statistically related to the proposed questions. Our results show that Brazilian youngsters do not have the habit of wearing long-sleeved clothing (<15% in summer), sunglasses (0.0%), or hats (2.1%). More than 40% had no knowledge about ultraviolet index (UVI), while another 30% misinterpreted what it is. Less than half of all students wear sunscreen when out in the sun. Despite this low PhP use-rate, more than 90% know that UVR causes skin cancers. Low income was the factor that showed the greatest number of significant relationships with respect to the lack of PhP. The findings suggest that current traditional PhP campaigns are not efficient. We propose that PhP should be part of school curricula from elementary school onwards. After all, the lack of educational programs predisposes these youngsters to an increased chance of skin diseases in the future.
The Effects of Radioligand Therapy on Quality of Life and Sexual Function in Patients with Neuroendocrine Neoplasms

Simple Summary Cancer therapies influence a patient’s health-related quality of life (HRQoL) and sexual function. Patients with neuroendocrine neoplasm (NEN) have impaired HRQoL and sexual function because of the long-lasting disease with a high tumor burden that requires multiple treatments with different mechanisms of action. Moreover, the complexity of symptoms may be due, at least to a certain extent, to the tumor secretion and release of polypeptides and biogenic amines that cause several clinical conditions including the carcinoid syndrome. Peptide receptor radionuclide therapy (PRRT) is an effective treatment in patients with NEN. Retrospective studies and randomized clinical trials have reported that patients with NEN treated with PRRT experienced an improvement in HRQoL evaluated by self-assessment questionnaires, such as the EORTC QLQ-C30 and QLQ-GINET21. The impact on sexual function has only been investigated in part through these questionnaires. This review discusses the current knowledge regarding the changes in HRQoL and sexual function in patients with NEN treated with PRRT. Abstract Peptide receptor radionuclide therapy (PRRT), also called radioligand therapy, is an effective antitumoral treatment in patients with neuroendocrine neoplasm (NEN). It improves the patient’s health-related quality of life (HRQoL), which is evaluated by self-assessment questionnaires. The aim of this narrative review was to report the current knowledge on the changes of HRQoL and sexual function in patients with NEN treated with PRRT. We conducted a literature search of the PubMed, Embase, and APA PsycInfo databases. We selected 15 studies (12 for HRQoL and three for sexual function). After treatment with PRRT, patients with NEN experienced a significant improvement in their global health status, disease-related worries, social and emotional functioning, and cancer-related symptoms such as fatigue and diarrhea. Other symptoms, such as nausea/vomiting, dyspnea, and constipation, as well as the economic impact, were unchanged by radioligand therapy. Data on sexual function were not equally promising; only a few studies investigated this issue by using appropriate questionnaires in patients treated with radioligand therapy. Therefore, additional studies are needed to draw a conclusion about the benefits from PRRT on sexual function.
Automatic matched-field tracking with table lookup

In matched-field processing, the signals measured at sensors in an array are correlated with the expected signals for a target at a specified point in the environment. This tends to be a computer intensive process because there are a large number of possible target locations and the calculation of the sound field may be complicated. A search by an operator for the target involves examination of various cuts through a multi-dimensional search space. In this paper it is shown that use of table lookup simplifies the modeling problem. Also, by use of matched-field tracking, the data can be processed in large time (∼3 to 10 min) blocks. Using these methods, the processing can be done in real time with little, or no, operator intervention. An example of automatic matched-field tracking is presented using data collected during a shallow water test near San Clemente Island. Finally, a simple sensitivity study is made. The actual sound speed profile is replaced by one modified by low-pass filtering and, in a secon.
2-45 Micron Infrared Spectroscopy of Carbon-rich Proto-Planetary Nebulae

Infrared Space Observatory (ISO) 2-45 μm observations of seven proto-planetary nebulae (PPNs) and two other carbon-rich objects are presented. The unidentified emission features at 21 and 30 μm are detected in six sources, including four new detections of the 30 μm feature. This previously unresolved 30 μm feature is now resolved and found to consist of a broad feature peaking at 27.2 μm (the "30 μm" feature) and a narrower feature at 25.5 μm (the "26 μm" feature). This new 26 μm feature is detected in eight sources and is particularly strong in IRAS Z02229+6208 and 16594-4656. The unidentified infrared (UIR) emission features at 3.3, 6.2, 7.7, and 11.3 μm, which are commonly observed in planetary nebulae and H II regions, are also seen in these PPNs. However, their strengths relative to the continuum plateaus at 8 and 12 μm are weaker than in planetary nebulae. The 6.9 μm feature, seen almost exclusively in PPNs, is strong. New millimeter CO and HCN observations were made; they support the carbon-rich nature of the objects and yield the expansion velocities of the gaseous envelopes. The spectral energy distributions of these PPNs were fitted with a radiative-transfer model, taking into account the emission features at 21, 26, and 30 μm. A significant fraction of the total energy output is emitted in these features: as high as 20% in the 30 μm feature and 8% in the 21 μm feature. The fact that so much energy is carried in these features suggests that the material responsible for these features must be made of abundant elements and most likely involves carbon. SiS2 appears to be ruled out as the emitter of the 21 μm feature due to the absence of a predicted companion feature.
Soy Isoflavones Induce Feminization of Japanese Eel (Anguilla japonica)

Under aquaculture conditions, Japanese eels (Anguilla japonica) produce a high percentage of males. However, females gain higher body weight and have better commercial value than males, and, therefore, a high female ratio is required in eel aquaculture. In this study, we examined the effects of isoflavones, genistein, and daidzein on sex differentiation and sex-specific genes of eels. To investigate the effects of these phytoestrogens on the gonadal sex, we explored the feminizing effects of soy isoflavones, genistein, and daidzein in a dose-dependent manner. The results showed that genistein induced feminization more efficiently than daidzein. To identify the molecular mechanisms of sex-specific genes, we performed a comprehensive expression analysis by quantitative real-time PCR and RNA sequencing. Phenotypic males and females were produced by feeding elvers a normal diet or an estradiol-17β- or genistein-treated diet for 45 days. The results showed that female-specific genes were up-regulated and male-specific genes were down-regulated in the gonads, suggesting that genistein induces feminization by altering the molecular pathways responsible for eel sex differentiation.
Experimental investigation of solar‐powered food steamer based on parabolic dish concentrator for domestic applications

Steam cooking is beneficial over other cooking techniques like boiling since it preserves more vitamins lost during other methods. In this study, a novel solar food steamer (SFS) based on a parabolic dish concentrator (PDC) is designed and constructed for domestic food preparation. A straightforward fabrication process of a 2.626 m2 PDC with design calculations is also presented. The system's instantaneous energy and exergy efficiency evaluation has been examined from different tests over three consecutive days. The system's high energetic and exergetic efficiency was achieved in the case of sweet potato, that is, 72.83% and 15.14%, respectively. In the case of dried chickpeas, the maximum steaming duration of 70 min was attained, along with an energy efficiency of 47.74% and an exergy efficiency of 10.07%. In addition, an economic analysis was performed to determine the payback time in terms of cost and utility. The payback time for the proposed method is 2.4 years. The SFS may save 43 kg/month of carbon dioxide from escaping into the atmosphere; it can be considered an environmentally valuable device.
Sleep Problems, Social Anxiety and Stuttering Severity in Adults Who Do and Adults Who Do Not Stutter

Background: While there is sufficient evidence that children and adolescents who stutter reported more impaired sleep compared to children and adolescents who did not stutter, findings among adults who stutter (AWS) were scarce. Furthermore, stuttering is associated with issues related to verbal communication in a social context. As such, it was conceivable that AWS reported higher scores for social anxiety, compared to adults who do not stutter (AWNS). In the present study, we tested whether AWS reported higher sleep complaints compared to AWNS. We further tested whether scores for social anxiety and stuttering independently predicted sleep disturbances. Methods: A total of 110 AWS (mean age; 28.25 years, 27.30% females) and 162 AWNS (mean age; 29.40 years, 51.20% females) completed a series of self-rating questionnaires covering sociodemographic information, sleep disturbances and social anxiety. Adults with stuttering further completed a questionnaire on stuttering. Results: Compared to AWNS, AWS reported a shorter sleep duration, a lower sleep efficiency, higher scores for drug use in terms of sleep-promoting medications (significant p-values and medium effect sizes), and an overall higher PSQI score (significant p-values and large effect size), when controlling for age and social anxiety. Next, while p-values were always significant for subjective sleep quality, sleep disturbances, and daytime functioning, when controlling for age and social anxiety, their effect sizes were trivial or small. For sleep latency, the p-value was not significant and the effect size was trivial. Among AWS, higher scores for stuttering and older age, but not social anxiety, predicted higher sleep disturbances. The association between higher sleep disturbances and higher stuttering severity was greatest among those AWS with highest scores for social anxiety. Conclusions: When compared to AWNS, AWS self-reported higher sleep disturbances, which were associated with older age, and higher scores for stuttering severity, but not with social anxiety. Adults who stutter might be routinely asked for their sleep quality.
Automated image standardization of the synoptic solar observations at the Meudon observatoryobservations at the Meudon Observatory

The robust techniques developed to put the synoptic solar images into a standardized form of a 'virtual solar image' are presented. The techniques include limb fitting, removal of geometrical distortion, centre position and size standardization and intensity normalization. The limb fitting starts with an initial estimate of the solar centre using raw 12-bit image data and then applies a Canny edge-detection routine. Candidate edge points for the limb are selected using a voting method and the chosen points fitted to a quadratic function by minimizing the algebraic distance using SVD. The five parameters of the ellipse fitting the limb are extracted from the quadratic function. Together with knowledge of cause of the geometrical distortion these parameters are used to define an affine transformation that corrects the image shape. Corrected images are generated using the nearest neighbor, bilinear or bicubic interpolation. Intensity renormalization is also required because of a limb darkening and variation in the atmosphere visibility over the solar disc. It is achieved by fitting a background function in polar co-ordinates to a set of sample points having the median intensities and by standardizing the average brightness. Representative examples of intermediate and final processed results are presented in addition to the algorithms developed. The techniques were also applied to the some images taken from BBSO, Kanzelhoehe and Kiepenheuer Institution observatories. The research is done for the European Grid of Solar Observations (EGSO) project, IST-2001-32409.
Internet Development, Consumption Upgrading and Carbon Emissions—An Empirical Study from China

Internet development has changed Chinese people’s consumption behavior, gradually expanding from survival consumption (SC) to development and enjoyment consumption (DEC) trends. Consumption is the new engine driving China’s economic growth and the terminal of carbon emissions. Simultaneously, China is undergoing a profound change toward the “double carbon” goal, the space for carbon emission reduction in traditional fields is gradually compressed. Therefore, it is necessary to explore carbon emissions from the perspective of consumption terminals. Based on provincial panel data, we use the fixed effects model and mediating effects model to explore the relationship between Internet development, consumption upgrading, and carbon emissions in a unified research framework. The findings show that: (1) Internet development leads to an increase in carbon emissions. A finding remains significant after using instrumental variables to mitigate endogeneity; (2) Internet development promotes consumption upgrading, reflected in development and enjoyment consumption expenditure; (3) Internet development contributes to increasing carbon emissions through consumption upgrading. Heterogeneity analysis shows that Internet development in eastern China significantly contributes to carbon emissions through consumption upgrading, while it is insignificant in central and western regions. The Internet development leading region contributes to an increase in carbon emissions through consumption upgrading. In comparison, the lagging region is insignificant. This study can provide a reference for policymakers in China or other countries to formulate energy-saving and emission-reduction policies in the Internet industry and provide a scientific basis for advocating people’s low-carbon consumption behavior and achieving carbon emission reduction at the consumption terminal.
The Regulatory Mechanism of miR-574-5p Expression in Cancer

MicroRNAs (miRNAs) are a group of small, single-stranded, non-coding RNAs approximately 22 nucleotides in length. The dysregulation of miRNAs has been widely investigated in various pathological processes, including tumorigenesis, providing a biomarker for cancer diagnosis and prognosis. As a member of the miRNA family, miR-574-5p is located on the human chromosome 4p14 and is highly correlated with a high incidence of human cancers. Functional pathways as well as underlying novel mechanisms upregulate or downregulate miR-574-5p, which plays an important regulatory role in tumorigenesis and progression. In this review, we systematically summarize the context-dependent implications of miR-574-5p and review differences in miR-574-5p expression in cancer. We also investigate the intricate functions exerted by miR-574-5p in diverse pathological processes and highlight regulatory pathways, networks, and other underlying novel mechanisms. The clinical applications of miR-574-5p as a diagnostic biomarker, prognostic biomarker, and therapeutic mechanism are also discussed in this paper. On this basis, we anticipate that miR-574-5p will be a promising and effective biomarker and therapeutic target.
Dual-Polarized Dual-Band Antenna-on-Display Using Via-Less and Single-Layer Topology for mmWave Wireless Scenarios

In this letter, a dual-polarized dual-band antenna-on-display (AoD) is proposed for millimeter-wave (mmWave) wireless scenarios. The proposed AoD schematic supports patch and monopole mode based on a shared aperture and antenna feed network concept. The devised AoD exhibits dual resonance with <inline-formula><tex-math notation="LaTeX">$ - $</tex-math></inline-formula>10 dB <italic>S</italic><sub>11</sub> bandwidth of 26–31 GHz (17.8%) and 33–40.5 GHz (19%). Based on the proposed unit element, a 1 × 4 phased array AoD is exemplified to verify its beam steering capability. The measured beam scanning angles demonstrate <inline-formula><tex-math notation="LaTeX">$ \pm $</tex-math></inline-formula>40<inline-formula><tex-math notation="LaTeX">$^\circ $</tex-math></inline-formula> at 28 GHz and <inline-formula><tex-math notation="LaTeX">$ \pm $</tex-math></inline-formula> 37<inline-formula><tex-math notation="LaTeX">$^\circ $</tex-math></inline-formula> at 38 GHz with ±45<inline-formula><tex-math notation="LaTeX">$^\circ $</tex-math></inline-formula> polarization. The proposed work is the first to realize multipolarized, multiband AoD under realistic conditions. This letter aims to suggest a principal example for future multiband mmWave wireless scenarios using display panel as antennas.
Possible events, actual events, and robots

To plan means reasoning about possible actions, but a robot must also reason about actual events. This paper proposes a formal theory about actual and possible events. It presents a new modal logic as a notation for this theory and a technique for planning in the modal logic using a first‐order theorem prover augmented with simple modal reasoning. This avoids the need for a general modal‐logic theorem prover. Adding beliefs to this theory raises an interesting problem for which the paper offers a tentative solution.
Preclinical and Clinical Applications of Metabolomics and Proteomics in Glioblastoma Research

Glioblastoma (GB) is a primary malignancy of the central nervous system that is classified by the WHO as a grade IV astrocytoma. Despite decades of research, several aspects about the biology of GB are still unclear. Its pathogenesis and resistance mechanisms are poorly understood, and methods to optimize patient diagnosis and prognosis remain a bottle neck owing to the heterogeneity of the malignancy. The field of omics has recently gained traction, as it can aid in understanding the dynamic spatiotemporal regulatory network of enzymes and metabolites that allows cancer cells to adjust to their surroundings to promote tumor development. In combination with other omics techniques, proteomic and metabolomic investigations, which are a potent means for examining a variety of metabolic enzymes as well as intermediate metabolites, might offer crucial information in this area. Therefore, this review intends to stress the major contribution these tools have made in GB clinical and preclinical research and highlights the crucial impacts made by the integrative “omics” approach in reducing some of the therapeutic challenges associated with GB research and treatment. Thus, our study can purvey the use of these powerful tools in research by serving as a hub that particularly summarizes studies employing metabolomics and proteomics in the realm of GB diagnosis, treatment, and prognosis.
Lipid kinase PIK3C3 maintains healthy brown and white adipose tissues to prevent metabolic diseases

Significance Uncontrolled reduction of fat tissues can cause an array of diseases that include diabetes but mechanisms remain to be fully defined. Autophagy, a cellular self-eating process, takes part in regulating the health of fat tissues. We investigated the role of an autophagy-participating factor named PIK3C3 in fat cell health and related metabolic diseases. We have found that the absence of PIK3C3 in fat cells of mice causes defects in the differentiation, survival, and function of fat cells, resulting in compromised body temperature control, abnormal blood lipid levels, fatty liver, and diabetes that resemble the abnormalities seen in patients with lipodystrophy. These findings reveal a crucial role for PIK3C3 in fat tissues, with potential therapeutic implications.
MicroRNAs in T Cell-Immunotherapy

MicroRNAs (miRNAs) act as master regulators of gene expression in homeostasis and disease. Despite the rapidly growing body of evidence on the theranostic potential of restoring miRNA levels in pre-clinical models, the translation into clinics remains limited. Here, we review the current knowledge of miRNAs as T-cell targeting immunotherapeutic tools, and we offer an overview of the recent advances in miRNA delivery strategies, clinical trials and future perspectives in RNA interference technologies.