Miracle-dz/UniFAR-FTUs huggingface dataset:
Evaluation of compiler optimizations for Fortran D on MIMD distributed memory machines

The Fortran D compiler uses data decomposition specifications to automatically translate Fortran programs for execution on MIMD distributed-memory machines. This paper introduces and classifies a number of advanced optimizations needed to achieve acceptable performance; they are analyzed and empirically evaluated for stencil computations. Profitability formulas are derived for each optimization. Results show that exploiting parallelism for pipelined computations, reductions, and scans is vital. Message vectorization, collective communication, and efficient coarse-grain pipelining also significantly affect performance.
993 International Conference on Parallel Processing Evaluating the Impact of Cache Interferences on Numerical Codes *

In numerical codes, the regular interleaved accesses that occur within do-loop nests induce cache interference phe¬ nomena that can severely degrade program performance. Cache interferences can significantly increase the volume of memory traffic and the amount of communication in uniprocessors and multiprocessors. In this paper, we iden¬ tify cache interference phenomena, determine their causes and the conditions under which they occur. Based on these results, we derive a methodology for computing an analyt¬ ical expression of cache misses for most classic loop nests, which can be used for precise performance analysis and prediction. We show that cache performance is unstable, because some unexpected parameters such as arrays base address can play a significant role in interference phenom¬ ena. We also show that the impact of cache interferences can be so high, that the benefits of current data local¬ ity optimization techniques can be partially, if not totally, eradicated.
Unexpected windfalls, education, and mental health: evidence from lottery winners in Germany

ABSTRACT This paper investigates the causal impact of large unexpected windfalls on individual mental health, physical health, as well as health behaviors. I use a large individual-level panel data set of lottery winners from Germany between the years 2000 and 2011 and observe lottery winners before and after winning a large lottery prize. Mental health declines immediately after winning a large lottery prize for individuals with low education and low levels of financial literacy. While these individuals report being happier after winning the lottery, evidence from commonly used SF-12 measures of mental health indicates that winners with low education experience increased role limitations due to emotional problems, are more anxious, and have less energy after their win. The impact on various measures of mental health is highly robust, statistically significant, economically significant, and persists for up to two years after the win. Unexpected windfalls have no impact on the mental health of individuals with high education or high financial literacy. Winning the lottery has no impact on individuals’ health behaviors such as smoking or alcohol consumption, and it has no impact on doctor visits, hospital stays, or illness-related work absences regardless of education level.
Comprehensive Assessment of Coronary Plaque Progression With Advanced Intravascular Imaging, Physiological Measures, and Wall Shear Stress: A Pilot Double‐Blinded Randomized Controlled Clinical Trial of Nebivolol Versus Atenolol in Nonobstructive Coronary Artery Disease

Background We hypothesized that nebivolol, a β‐blocker with nitric oxide–mediated activity, compared with atenolol, a β‐blocker without such activity, would decrease oxidative stress and improve the effects of endothelial dysfunction and wall shear stress (WSS), thereby reducing atherosclerosis progression and vulnerability in patients with nonobstructive coronary artery disease. Methods and Results In this pilot double‐blinded randomized controlled trial, 24 patients treated for 1 year with nebivolol 10 mg versus atenolol 100 mg plus standard medical therapy underwent baseline and follow‐up coronary angiography with assessments of inflammatory and oxidative stress biomarkers, microvascular function, endothelial function, and virtual histology intravascular ultrasound. WSS was calculated from computational fluid dynamics. Virtual histology intravascular ultrasound segments were assessed for vessel volumetrics and remodeling. There was a trend toward more low‐WSS segments in the nebivolol cohort (P=0.06). Low‐WSS regions were associated with greater plaque progression (P<0.0001) and constrictive remodeling (P=0.04); conversely, high‐WSS segments demonstrated plaque regression and excessive expansive remodeling. Nebivolol patients had decreased lumen and vessel areas along with increased plaque area, resulting in more constrictive remodeling (P=0.002). There were no significant differences in biomarker levels, microvascular function, endothelial function, or number of thin‐capped fibroatheromas per vessel. Importantly, after adjusting for β‐blocker, low‐WSS segments remained significantly associated with lumen loss and plaque progression. Conclusion Nebivolol, compared with atenolol, was associated with greater plaque progression and constrictive remodeling, likely driven by more low‐WSS segments in the nebivolol arm. Both β‐blockers had similar effects on oxidative stress, microvascular function, and endothelial function. Clinical Trial Registration URL: https://clinicaltrials.gov/. Unique identifier: NCT01230892.
Topical tacrolimus is not effective in chronic plaque psoriasis. A pilot study.

BACKGROUND Cyclosporine for the treatment of psoriasis constitutes a new approach. Alternative systemic cyclosporine derivatives have been studied to find an immunosuppressive drug with fewer adverse effects. Tacrolimus is one of these new immunosuppressive drugs. Systematically, it has been proven effective in treating psoriasis. A topical formulation of tacrolimus is attractive because it has fewer adverse effects and is useful for a large group of patients. We report for the first time on the efficacy of nonocclusive topical tacrolimus in the treatment of psoriasis. OBSERVATIONS After a washout phase of 2 weeks, patients were randomized to receive 0.005% calcipotriol ointment twice daily, placebo ointment once daily, or 0.3% tacrolimus ointment once daily. One psoriatic plaque was treated with a surface area of 40 to 200 cm2. Efficacy was estimated using the local psoriasis severity index. The reduction in the local psoriasis severity index score after 6 weeks was 62.5% in the calcipotriol group, 33.3% in the tacrolimus group, and 42.9% in the placebo group. CONCLUSIONS There was no statistically significant difference between the efficacy of tacrolimus and placebo ointment (P = .77). Calcipotriol ointment, applied twice daily, had a better effect than tacrolimus ointment and placebo ointment once daily.
Anomaly Detection in network traffic and role of wavelets

Network Anomaly Detection covers wide area of research. Current best practices for identifying and diagnosing traffic anomalies consist of visualizing traffic from different perspectives and identifying anomalies from prior experience. Different tools have been developed to automatically generate alerts to failures, but to automate the anomaly identification process remains a challenge. Recently, Signal Processing techniques have found applications in Network Intrusion Detection System because of their ability in detecting novel intrusions and attacks, which cannot be achieved by signature-based detection systems. Visualization techniques are ways of creating and handling graphical representations of data. This survey explains the main techniques known in the field of Statistical based and Wavelet based anomaly detection approaches and focuses on the role of data traffic visualization tools in network traffic anomaly detection.
Gyroscopic forces for mechanical manipulators

It has long been a challenge to control the end-effector trajectory of mechanical manipulators using only taskspace parameterization. While there exist some taskspace control strategies (such as the potential energy shaping) that guarantee the convergence of the end-effector to the target point without any inverse transformations, how to make the end-effector follow a desired path during the intermediate motion or to make it remain in certain subsets of taskspace, without resorting to inverse kinematics or inverse dynamics in one way or other, is still challenging. This paper studies the gyroscopic force as an auxiliary control action that can realize the desired motion profile of the end-effector without using any inverse transformations. Gyroscopic force is a specific type of force that does not affect the mechanical energy because its direction is always orthogonal to the velocity. This paper presents several ways to parameterize the artificial gyroscopic force with respect to the desired path profile of the end-effector as well as the desired velocity field that is often used as an indirect way to specify the target path. The formulated gyroscopic force is combined with the taskspace potential energy shaping control law to achieve the target tracking and the path following at the same time free from any inverse transformation. Simulation results are presented to validate the performance of proposed control strategies.
Analysis of the decay of some effects of modification of polylactide surface layers

The results of an investigation into the effects of modifying a surface layer (SL) of polylactide (PLA) as a function of time are presented. The PLA modification was performed by the method of corona discharges (CD) in the air using unit energy values (Eu) equal to 3.5 and 10 kJ/m2. The extent of oxidation and contact angle of the SL were determined by the methods of X-ray photoelectron spectroscopy (XPS) and goniometry, respectively. The measurements were carried out immediately after the modification process, as well as 1, 2, and 3 months later.
Direct electrospinning of highly twisted, continuous nanofiber yarns

Yarns are key building blocks to construct complicated fibrous structures for diverse applications. Although carbon nanotube yarns have been fabricated by a few novel techniques, challenges still remain in processing other nano fibrous materials into yarns, especially during the fiber fabricating process. In this paper, we report a simple but efficient and versatile method to prepare well‐twisted continuous nanofiber yarns directly through an electrospinning process. The yarn electrospinning process used two oppositely charged electrospinning nozzles to generate a hollow nanofiber “cone” on an intermediate funnel collector. Continuous nanofiber yarns can be directly withdrawn from the “cone” apex, with up to 7400 turns per meter of twists inserted through the rotation of the funnel. The maximum yarn production rate is 5 m/min, and the yarn twist level and fiber orientation can be controlled by the funnel rotating speed and yarn withdrawal rate. The yarn tensile properties showed dependence on the twist level.
Adaptive reduced-rank least squares beamforming algorithm based on the set-membership framework

This paper presents a new adaptive algorithm for the linearly constrained minimum variance (LCMV) beamformer design. We incorporate the set-membership filtering (SMF) mechanism into the reduced-rank joint iterative optimization (JIO) scheme to develop a constrained recursive least squares (RLS) based algorithm called JIO-SM-RLS. The proposed algorithm inherits the positive features of reduced-rank signal processing techniques to enhance the output performance, and utilizes the data-selective updates (around 10–15%) of the SMF methodology to save the computational cost significantly. An effective time-varying bound is imposed on the array output as a constraint to circumvent the risk of overbounding or underbounding, and to update the parameters for beamforming. The updated parameters construct a set of solutions (a membership set) that satisfy the constraints of the LCMV beamformer. Simulations are performed to show the superior performance of the proposed algorithm in terms of the convergence rate and the reduced computational complexity in comparison with the existing methods.
The geometry of D = 11 Killing spinors

We propose a way to classify the local form of all bosonic supersymmetric configurations of D = 11 supergravity, using the differential forms that can be constructed as bi-linears from the Killing spinors. We show that the most general bosonic geometries either have a privileged SU(5) or a (Spin(7)8) × structure, depending on whether the Killing vector constructed from the Killing spinor is timelike or null, respectively. In the time-like case we derive the general local form of the geometry and show that it is almost completely determined by a certain SU(5) structure on the ten-dimensional space orthogonal to the orbits of the Killing vector. We also deduce what further conditions must be imposed in order that the equations of motion are satisfied. We illustrate the formalism with some known solutions and also present some new solutions including a rotating generalisation of the resolved membrane solutions and generalisations of the recently constructed D = 11 Godel solution. We also prove some general vanishing theorems for compactifications with flux.
GRIP: Scalable 3D global routing using Integer Programming

We propose GRIP, a scalable global routing technique via Integer Programming (IP). GRIP optimizes wirelength and via cost without going through a layer assignment phase. GRIP selects the route for each net from a set of candidate routes that are generated based on an estimate of congestion generated by a linear programming pricing phase. To achieve scalability, the original IP is decomposed into smaller ones corresponding to balanced rectangular subregions on the chip. We introduce the concept of a floating terminal for a net, which allows flexibility to route long nets going through multiple subregions. We also use the IP to plan the routing of long nets, detouring them from congested subregions. For ISPD 2007 benchmarks, we obtain 3.9% and 11.3% average improvement in wirelength and via cost for the 2D and 3D versions respectively, compared to the best results reported in the open literature.
Control of annealing texture and earing in non-hardenable aluminium alloys

AbstractFactors affecting textures in non-hardenable aluminium alloys are considered on the basis of published results and some new experimental results. Emphasis is placed on conditions relevant to industrial scale rolling and annealing of sheet products. The most commonly observed texture components in these alloys are summarised, together with available evidence regarding their origins. Hot rolling conditions have a powerful effect on subsequent annealing textures, which is attributed to the microstructural state of the material before cold rolling. This can influence the relative frequency of different nucleation mechanisms. Heat treatment of the hot rolled band can also bring about marked changes in texture and earing for the same reason. The effect of cold rolling reduction on texture is complex and depends on the initial microstructure; increasing reduction promotes an increasingly heterogeneous substructure. The main impurity in these alloys is iron, which plays several different roles in controll.
Fusion of Event Data Stream and Background Knowledge for Semantic-Enabled CEP

Usage of ontological knowledge about events and their relations to other concepts in the application domain can improve the quality of complex event processing (CEP). In this paper, we present a solution for knowledge-based event entity extraction using background knowledge bases. For our experiments we use the DeRiVE-2011 workshop dataset. We enrich the incoming event data stream with background knowledge from an external knowledge base, e.g., DBPedia so that our event processing engine has more knowledge about events and their relations to other concepts in application domain. 1
Universal Spatiotemporal Sampling Sets for Discrete Spatially Invariant Evolution Processes

Let <inline-formula> <tex-math notation="LaTeX">$(I,+)$ </tex-math></inline-formula> be a finite abelian group and <inline-formula> <tex-math notation="LaTeX">$\mathbf {A}$ </tex-math></inline-formula> be a circular convolution operator on <inline-formula> <tex-math notation="LaTeX">$\ell ^{2}(I)$ </tex-math></inline-formula>. The problem under consideration is how to construct minimal <inline-formula> <tex-math notation="LaTeX">$\Omega \subset I$ </tex-math></inline-formula> and <inline-formula> <tex-math notation="LaTeX">$l_{i}$ </tex-math></inline-formula> such that <inline-formula> <tex-math notation="LaTeX">$Y=\{\mathbf {e}_{i}, \mathbf {A}\mathbf {e}_{i}, \cdots , \mathbf {A}^{l_{i}}\mathbf {e}_{i}: i\in \Omega \}$ </tex-math></inline-formula> is a frame for <inline-formula> <tex-math notation="LaTeX">$\ell ^{2}(I)$ </tex-math></inline-formula>, where <inline-formula> <tex-math notation="LaTeX">$\{\mathbf {e}_{i}: i\in I\}$ </tex-math></inline-formula> is the canonical basis of <inline-formula> <tex-math notation="LaTeX">$\ell ^{2}(I)$ </tex-math></inline-formula>. This problem is motivated by the spatiotemporal sampling problem in discrete spatially invariant evolution processes. We will show that the cardinality of <inline-formula> <tex-math notation="LaTeX">$\Omega $ </tex-math></inline-formula> should be at least equal to the largest geometric multiplicity of eigenvalues of <inline-formula> <tex-math notation="LaTeX">$\mathbf {A}$ </tex-math></inline-formula>, and consider the universal spatiotemporal sampling sets <inline-formula> <tex-math notation="LaTeX">$(\Omega , l_{i})$ </tex-math></inline-formula> for convolution operators whose eigenvalues subject to the same largest geometric multiplicity. We will give an algebraic characterization for such sampling sets and show how this problem is linked with sparse signal processing theory and polynomial interpolation theory.
Production of indole diterpenes by Aspergillus alliaceus

Production of two related indole diterpenes (differing by a dimethyl leucine side chain) by Aspergillus alliaceus was improved through several pilot scale fermentations. Media were optimized through focus primarily on initial increases, as well as mid‐cycle additions, of carbon and nitrogen sources. Fermentation conditions were improved by varying ventilation conditions using various combinations of air flowrate and back‐pressure set points. Production improvements were quantified based on total indole diterpene concentration as well as the ratio of the major‐to‐minor by‐product components. Those changes with a positive substantial impact primarily on total indole diterpene concentration included early cycle glycerol shots and enhanced ventilation conditions (high air flowrate, low back‐pressure). Those changes with a significant impact primarily on ratio included higher initial cerelose, soybean oil, monosodium glutamate, tryptophan, or ammonium sulfate concentrations, higher broth pH, and enhanced ventilation conditions. A few changes (higher initial glycerol and monosodium glutamate concentrations) resulted in less notable and desirable titer or ratio changes when implemented individually, but they were adopted to more fully realize the impact of other improvements or to simplify processing. Overall, total indole diterpene titers were improved at the 600 L pilot scale from 125–175 mg/L with a ratio of about 2.1 to 200–260 mg/L with a ratio of about 3.3–4.5. Thus, the ability to optimize total indole diterpene titer and/or ratio readily exists for secondary metabolite production using Aspergillus cultures. © 2006 Wiley Periodicals, Inc.
A prospective investigation of the development of borderline personality symptoms

Abstract The antecedents and developmental course of borderline personality disorder symptoms were examined prospectively from infancy to adulthood using longitudinal data from a risk sample (N = 162). Borderline personality disorder symptom counts were derived from the Structured Clinical Interview for DSM Disorders diagnostic interview at age 28 years. Correlational analyses confirmed expected relations between borderline symptoms and contemporary adult disturbance (e.g., self-injurious behavior, dissociative symptoms, drug use, relational violence) as well as maltreatment history. Antecedent correlational and regression analyses revealed significant links between borderline symptoms in adulthood and endogenous (i.e., temperament) and environmental (e.g., attachment disorganization, parental hostility) history in early childhood and disturbance across domains of child functioning (e.g., attention, emotion, behavior, relationship, self-representation) in middle childhood/early adolescence. Process analyses revealed a significant mediating effect of self-representation on the relation between attachment disorganization on borderline symptoms. The findings are discussed within a developmental psychopathology framework in which disturbance in self-processes is constructed through successive transactions between the individual and environment.
[Cerebral hemorrhage in Sneddon syndrome].

INTRODUCTION Sneddon syndrome is the association of livedo retricularis and cerebrovascular lesions. It is a vasculopathy of vessels of small and medium calibre which affects young people and is of unknown origin. It is often associated with arterial hypertension and repeated ischemic cerebrovascular accidents which lead to intellectual deterioration. CLINICAL CASE We describe a 49 year old man who, from the age of 23, had had repeated transient or established episodes compatible with ischemic cerebrovascular accidents. These were followed by various neurological sequelae and by intellectual deterioration. Finally he died of a cerebral hemorrhage whilst on anticoagulant treatment with Synthron. We show the neuroimaging findings (CT, MR and angiography) and the neuropathological studies (cerebral hemorrhage, fibrosis of the intima of the vessels of the circle of Willis, absence of inflammation, bilateral unsymmetrical leukoencephalopathy of the cerebral hemispheres and multiple cortical infarcts). CONCLUSION We wish to draw attention to the occurrence of this complication, its possible relationship to the vasculopathy mentioned, bursting of one of the arteries of the revascularization complex, arterial hypertension or anticoagulant treatment, and also to add one more case to the few described as having hemorrhage and neuropathology in Sneddon syndrome.