Miracle-dz/UniFAR-FTUs huggingface dataset:
Just in sequence delivery improvement based on Flexsim simulation experiment

Nowadays, automotive industry is focused at satisfying at maximum individual demands of the consumers. It is related with a wide range of offered products, which becomes a challenge for logistics. Limited space around an assembly line, necessity for assuring continuity of production, high costs of storing stock and storage space force people to use JIS delivery. This kind of delivery is a complex process, which depends on many factors such as tact time, quantity of parts in transport container, etc. It opens possibilities for using different kinds of technology, e.g. computer simulation. Present paper shows the example application of simulation in logistics process. The main problem to solve was the quantity of containers in sequencing delivery process of car windows. Article presents the problem definition, structure of build model, tool construction and some of the experiments which were made on the simulation model.
Cyclin D1 overexpression versus response to induction chemotherapy in squamous cell carcinoma of the head and neck--preliminary report.

The aim of this study was to investigate whether there is an association between overexpression of cyclin D1 and response to therapy. Immunohistochemical overexpression of cyclin D1 was determined in paraffin-embedded specimens from diagnostic biopsies of 89 primary cases of squamous cell carcinoma of the head and neck (SCCHN), using a polyclonal antiserum. The tumor response rates were estimated after curative treatment (i.e. surgery and/or radiotherapy and/or chemotherapy). Patients whose tumors were overexpressing cyclin D1 showed complete or partial response to neoadjuvant chemotherapy with cisplatin/5-FU. In addition, a majority of cyclin D1 negative tumors did not respond at all to this treatment (p = 0.02, Fisher's exact test). This study indicates that immunohistochemical assessment of cyclin D1 expression in SCCHN could be a new predictive marker to select a subgroup of patients that will benefit from neoadjuvant chemotherapy.
Molecular magnetic resonance imaging of brain–immune interactions

Although the blood–brain barrier (BBB) was thought to protect the brain from the effects of the immune system, immune cells can nevertheless migrate from the blood to the brain, either as a cause or as a consequence of central nervous system (CNS) diseases, thus contributing to their evolution and outcome. Accordingly, as the interface between the CNS and the peripheral immune system, the BBB is critical during neuroinflammatory processes. In particular, endothelial cells are involved in the brain response to systemic or local inflammatory stimuli by regulating the cellular movement between the circulation and the brain parenchyma. While neuropathological conditions differ in etiology and in the way in which the inflammatory response is mounted and resolved, cellular mechanisms of neuroinflammation are probably similar. Accordingly, neuroinflammation is a hallmark and a decisive player of many CNS diseases. Thus, molecular magnetic resonance imaging (MRI) of inflammatory processes is a central theme of research in several neurological disorders focusing on a set of molecules expressed by endothelial cells, such as adhesion molecules (VCAM-1, ICAM-1, P-selectin, E-selectin, …), which emerge as therapeutic targets and biomarkers for neurological diseases. In this review, we will present the most recent advances in the field of preclinical molecular MRI. Moreover, we will discuss the possible translation of molecular MRI to the clinical setting with a particular emphasis on myeloperoxidase imaging, autologous cell tracking, and targeted iron oxide particles (USPIO, MPIO).
Efferent neurons and suspected interneurons in S-1 vibrissa cortex of the awake rabbit: receptive fields and axonal properties.

1. The behavioral tractability of the rabbit was exploited and enabled, in the fully awake state, receptive-field analysis of antidromically identified efferent neurons within the vibrissa representation of primary somatosensory cortex (S-1). Efferent neurons studied included ipsilateral corticocortical neurons (C-IC neurons, n = 56) that project to or beyond the second somatosensory cortical area (S-2) and corticofugal neurons of layer 5 (CF-5 neurons, n = 75) and layer 6 (CF-6 neurons, n = 92) that project to and/or beyond the thalamus. 2. An additional class of neurons was studied that was not activated antidromically from any stimulus site, but which responded synaptically to electrical stimulation of the ventrobasal (VB) thalamus with a burst of three or more spikes at frequencies of 600 to greater than 900 Hz. Most of these neurons also responded synaptically to stimulation of S-2. The action potentials of these neurons were much shorter (mean = 0.43 ms), than those of efferent neurons (mean = 0.98 ms). Such properties have been associated with interneurons found throughout the central nervous system, and these neurons are thereby referred to as suspected interneurons (SINs). Although SINs were found at all cortical depths, a strong peak in the distribution occurred just superficial to the peak in the distribution of CF-5 neurons. Most SINs located within this peak responded to deflection of only a single vibrissa. In contrast, SINs located in layer 6 and in layer 2-3 responded to deflection of many vibrissae (median = 11.0 and 5.5 vibrissae, respectively). In addition, SINs of layer 6 and layer 2-3 had significantly longer synaptic latencies to stimulation of VB thalamus than did SINs located at intermediate cortical depths. 3. The properties of efferent neurons and SINs differed considerably. Efferent neurons never responded to stimulation of VB thalamus with the high-frequency burst of spikes characteristic of SINs. Although greater than 70% of CF-6, CF-5 and C-IC neurons had receptive fields that were directionally selective, only 20% of SINs showed any degree of directional selectivity. Furthermore, SINs showed both much lower angular thresholds to vibrissa deflection and a much greater ability to follow high-stimulus frequencies than was seen in efferent neurons. The spontaneous firing rates of SINs had a mean value of 16.5 spikes/s, which was the highest seen in any population within S-1. 4. CF-5 neurons had a number of properties which contrasted with those of both CF-6 and C-IC neurons. (ABSTRACT TRUNCATED AT 400 WORDS)
Modal-set estimation with an application to clustering

We present a first procedure that can estimate -- with statistical consistency guarantees -- any local-maxima of a density, under benign distributional conditions. The procedure estimates all such local maxima, or $\textit{modal-sets}$, of any bounded shape or dimension, including usual point-modes. In practice, modal-sets can arise as dense low-dimensional structures in noisy data, and more generally serve to better model the rich variety of locally-high-density structures in data. The procedure is then shown to be competitive on clustering applications, and moreover is quite stable to a wide range of settings of its tuning parameter.
A hierarchical approach to energy management in data centers

This paper concerns the management of energy in data centers using a cyber-physical model that supports the coordinated control of both computational and thermal (cooling) resources. On the basis of the structure of the proposed model and practical issues related to the data center layout and distribution of information, we propose a hierarchical optimization scheme in which the higher level chooses goals for regulation at the lower level. Linear programming is applied to solve sequences of one-step look-ahead problems at both the top level and in the lower-level controllers to solve. The approach is illustrated with simulation results.
Viewable scene modeling for geospatial video search

Video sensors are becoming ubiquitous and the volume of captured video material is very large. Therefore, tools for searching video databases are indispensable. Current techniques that extract features purely based on the visual signals of a video are struggling to achieve good results. By considering video related meta-information, more relevant and precisely delimited search results can be obtained. In this study we propose a novel approach for querying videos based on the notion that the geographical location of the captured scene in addition to the location of a camera can provide valuable information and may be used as a search criterion in many applications. This study provides an estimation model of the viewable area of a scene for indexing and searching and reports on a prototype implementation. Among our objectives is to stimulate a discussion of these topics in the research community as information fusion of different georeferenced data sources is becoming increasingly important. Initial results illustrate the feasibility of the proposed approach.
Study on Temperature Field of L-Phenylalanine Fermentation in Heat Pipe Bioreactor

L-phenylalanine fermentation (L-Phe) is produced by the preparation method of PPA-transamination using the ferment liquor, which is the production of the E.coli No.1 fermented in heat pipe bioreactor (HPBR), the technical indexes are superior. The temperature profile of ferment liquor in the period of microbe growth is well distributed, the mean difference in temperature is 0.08°C, while the maximum value is 0.4°C.Base on operational principle of heat pipe, HPBR solves many problems on heat transfer in traditional bioreactor: nonuniformity of temperature profile, inefficiency of heat transfer etc. The study in-depth on transfer process in HPBR will effectively accelerate exploitation for new-style bioreactor and advancement of biotechnology.
Thom Polynomials and Schur Functions: The Singularities A3(−)

Combining the “method of restriction equations” of Rimányi et al. with the techniques of symmetric functions, we establish the Schur function expansions of the Thom polynomials for the Morin singularities A3 : (C•, 0)→ (C•+k, 0) for any nonnegative integer k. 2010 Mathematics Subject Classification: 05E05, 14N10, 57R45.
New Typical Vector of Neurotoxin β-N-Methylamino-l-Alanine (BMAA) in the Marine Benthic Ecosystem

The neurotoxin β-N-methylamino-l-alanine (BMAA) has been identified as an environmental factor triggering neurodegenerative diseases such as Amyotrophic Lateral Sclerosis (ALS) and Alzheimer’s disease (AD). We investigated the possible vectors of BMAA and its isomers 2,4-diaminobutyric acid (DAB) and N-2(aminoethyl)glycine (AEG) in marine mollusks collected from the Chinese coast. Sixty-eight samples of marine mollusks were collected along the Chinese coast in 2016, and were analyzed by an HILIC-MS/MS (hydrophilic interaction liquid chromatography with tandem quadrupole mass spectrometer) method without derivatization. BMAA was detected in a total of five samples from three species: Neverita didyma, Solen strictus, and Mytilus coruscus. The top three concentrations of free-form BMAA (0.99~3.97 μg·g−1 wet weight) were detected in N. didyma. DAB was universally detected in most of the mollusk samples (53/68) with no species-specific or regional differences (0.051~2.65 μg·g−1 wet weight). No AEG was detected in any mollusk samples tested here. The results indicate that the gastropod N. didyma might be an important vector of the neurotoxin BMAA in the Chinese marine ecosystem. The neurotoxin DAB was universally present in marine bivalve and gastropod mollusks. Since N. didyma is consumed by humans, we suggest that the origin and risk of BMAA and DAB toxins in the marine ecosystem should be further investigated in the future.
Cooperative File Sharing in Hybrid Delay Tolerant Networks

Peer-to-peer file sharing techniques are efficient and popular ways to distribute network media contents. Aiming to improve the accessibility of media contents from mobile devices, we introduce peer-to-peer file sharing technique into delay tolerant networks (DTNs), which are formed solely by highly mobile devices and which distribute files utilizing the mobility of humans and vehicles. We first investigate two important implementation issues in a DTN environment: cooperative file discovery and cooperative file download. We then propose several distributed file discovery and file download protocols under different levels of user cooperation. Finally, we conduct extensive simulations using both real and synthetic DTN traces to evaluate the proposed protocols.
The Effect of Compiler Optimizations on High-Level Synthesis-Generated Hardware

We consider the impact of compiler optimizations on the quality of high-level synthesis (HLS)-generated field-programmable gate array (FPGA) hardware. Using an HLS tool implemented within the state-of-the-art LLVM compiler, we study the effect of compiler optimizations on the hardware metrics of circuit area, execution cycles, FMax, and wall-clock time. We evaluate 56 different compiler optimizations implemented within LLVM and show that some optimizations significantly affect hardware quality. Moreover, we show that hardware quality is also affected by some optimization parameter values, as well as the order in which optimizations are applied. We then present a new HLS-directed approach to compiler optimizations, wherein we execute partial HLS and profiling at intermittent points in the optimization process and use the results to judiciously undo the impact of optimization passes predicted to be damaging to the generated hardware quality. Results show that our approach produces circuits with 16% better speed performance, on average, versus using the standard -O3 optimization level.
STRUCTURE THEORY OF L(ℝ, μ) AND ITS APPLICATIONS

Abstract In this paper, we explore the structure theory of L(ℝ, μ) under the hypothesis L(ℝ, μ) ⊧ “AD + μ is a normal fine measure on ” and give some applications. First we show that “ ZFC + there exist ω2 Woodin cardinals”1 has the same consistency strength as “ AD + ω1 is ℝ-supercompact”. During this process we show that if L(ℝ, μ) ⊧ AD then in fact L(ℝ, μ) ⊧ AD+. Next we prove important properties of L(ℝ, μ) including Σ1 -reflection and the uniqueness of μ in L(ℝ, μ). Then we give the computation of full HOD in L(ℝ, μ). Finally, we use Σ1 -reflection and ℙmax forcing to construct a certain ideal on (or equivalently on in this situation) that has the same consistency strength as “ZFC+ there exist ω2 Woodin cardinals. ”
Automatic music video summarization based on audio-visual-text analysis and alignment

In this paper, we propose a novel approach for automatic music video summarization based on audio-visual-text analysis and alignment. The music video is separated into the music and video tracks. For the music track, the chorus is detected based on music structure analysis. For the video track, we first segment the shots and classify the shots into close-up face shots and non-face shots, then we extract the lyrics and detect the most repeated lyrics from the shots. The music video summary is generated based on the alignment of boundaries of the detected chorus, shot class and the most repeated lyrics from the music video. The experiments on chorus detection, shot classification, and lyrics detection using 20 English music videos are described. Subjective user studies have been conducted to evaluate the quality and effectiveness of summary. The comparisons with the summaries based on our previous method and the manual method indicate that the results of summarization using the proposed method are better at meeting users' expectations.
Expressiveness of Definitions and Efficiency of Constructions in Computational Cryptography

The computational treatment of cryptography, and indeed any scientific treatment of a problem, is marked by its definitional side and by it constructive side. Results in this thesis better our understanding of both: on one side, they characterize the extent to which computational definitions capture the security of the basic task of symmetric encryption; on the other, they provide explicit bounds on the efficiency of commitment and secure two-party computation constructions. Specifically: (1) We relate the formal and computational treatments of symmetric encryption, obtaining a precise characterization of computational schemes whose computational semantics imply their formal semantics. We prove that this characterization is strictly weaker than previously-identified notions, and show how it may be realized in a simpler, more efficient manner. (2) We provide lower-bounds on the number of times a one-way permutation needs to be invoked (as a "black-box") in order to construct statistically-binding commitments. Our bounds are tight for the case of perfectly-binding schemes. (3) We show that the secure computation of any two-party functionality can be performed in an optimal two rounds of communication even in a setting that accounts for concurrent execution with other protocols (i.e., the Universal Composability framework). Here, we rely on the assumption that parties have access to a common reference string; some sort of setup is known to be necessary.
Increases in emergency department occupancy are associated with adverse 30-day outcomes.

OBJECTIVES The associations between emergency department (ED) crowding and patient outcomes have not been investigated comprehensively in different types of ED. The study objective was to examine the associations of changes over time in ED occupancy with patient outcomes in a sample of EDs that vary by size and location. A secondary objective was to explore whether the relationship between ED occupancy and patient outcomes differed by ED characteristics (size/type and medical and nursing staffing ratios). METHODS Using linked administrative databases, the authors constructed a cohort of 677,475 patients who visited one of 42 hospital EDs with complete data for 2005 on ED bed and waiting room occupancy. Crowding was measured with the relative occupancy ratio separately for ED bed and waiting room patients, defined as the ratio of ED occupancy on the day of the index ED visit to the average annual occupancy at that same ED. Multivariable logistic regression (adjusting for patient and ED characteristics) was used to analyze 30-day outcomes: mortality, return ED visits, and hospital admission at the first return ED visit. RESULTS After adjustment for ED and patient characteristics, a 10% increase in ED bed relative occupancy ratio was associated with 3% increases in death and hospital admission at a return visit. A 10% increase in ED waiting room crowding was associated with a small decrease in return visits. There was a stronger association between bed crowding and mortality among larger EDs. CONCLUSIONS In Quebec EDs, increases in bed occupancy are associated with an increase in the rates of 30-day adverse outcomes, even after adjustment for patient and ED characteristics. The results raise important concerns about the quality of care during periods of ED crowding.
Efficient planning of satellite-terrestrial hybrid networks for multicast applications

As the satellite technology will be one of the main components of the next generation Internet (NGI), a naturally occurring question concerns the feasibility of providing an efficient satellite-based Internet access. In this paper, we are interested in the problem of the planning of satellite-terrestrial hybrid networks for the multicast transfer. We first develop an architectural model for such type of networks, then we define the problem and we propose a planning heuristic that determines the suboptimal positions of satellite uplinks in a given terrestrial network. The proposed method minimizes the mean cost (the number of branches) of multicast trees for the unreliable multicast and the mean packet transfer delay for the reliable multicast. In addition, we develop a configuration policy of PIM-SM in hybrid networks concerning the choice of the list of rendezvous points (RPs) and the switching from the RP-routed tree to the shortest path tree. The obtained results demonstrate the ability of the proposed methods (the planning heuristic and the PIM-SM configuration policy) to improve the multicast performance criteria and to determine effectively the satellite uplink positions using PIM-SM combined with UDLR (unidirectional link routing).
Holographic Diffusers for Indoor Infrared Communication Systems

Diffused infrared transmission is one of thepreferred techniques used in indoor wirelesscommunications. Tolerance to shadowing and a lack ofalignment requirements are among the many advantagesoffered by this technique compared to the line-of-sighttechniques. However, it has its disadvantages, namelyhigh path loss and multipath dispersion. The limitationimposed by eye-safety requirements restricts the transmitted power. Therefore, efficient useof transmitted optical power is the key for practicalbroadband infrared systems. In this paper, we report onusing a holographic diffuser for shaping of infrared radiation pattern in an indoorinfrared transmission system. The holographic diffusershave the advantage of light weight and added flexibilityin the system design. The reported measurements show that employing a properly designed holographicdiffuser can reduce the path loss of a nondirectedoptical link. The results also show another advantage ofusing the proposed holographic diffuser, which is additional tolerance of the transmission toshadowing.
Three-Month and Long-Term Outcomes and Their Predictors in Acute Basilar Artery Occlusion Treated With Intra-Arterial Thrombolysis

Background and Purpose— Intra-arterial thrombolysis can be used for treatment of basilar artery occlusion. Predictors of outcome before initiation of treatment are of special interest. Methods— From 1992 to 2010, we treated 106 consecutive patients with basilar artery occlusion with intra-arterial thrombolysis. Baseline characteristics, treatment, clinical course, and 3-month and long-term outcomes (≥12 months) were assessed. Outcome parameters were vessel recanalization after treatment, complications, modified Rankin scale (mRS) score, and mortality after 3 months and in the long-term. Results— At 3 months, clinical outcome was good (mRS score, 0–2) in 33.0% of the patients and moderate (mRS score, 3) in 11.3%. Mortality was 40.6%. Partial or complete recanalization was achieved in 69.8% of the patients, and symptomatic intracranial hemorrhage occurred in 1 patient (0.9%). Between 3-month and long-term follow-up, 22 survivors (40.8%) showed clinical improvement of at least 1 point on the mRS score, 29 (53.7%) were functionally unchanged, and 3 (5.7%) showed functional worsening (P<0.0001). Multivariate analysis identified diabetes as a predictor of poor vessel recanalization (P=0.028). Low baseline National Institutes of Health Stroke Scale score was identified as a predictor of good or moderate clinical outcome (P<0.0001) and survival (P=0.001) at 3 months, and younger age was identified as an additional predictor of survival (P=0.012). For prediction of long-term clinical outcome, age was also an independent predictor (P=0.018). Conclusions— In our series, intra-arterial thrombolysis as treatment of basilar artery occlusion was safe. National Institutes of Health Stroke Scale score at admission and age were identified as predictors of outcome, and these predictors should be considered for treatment allocation in future randomized trials.