Miracle-dz/UniFAR-FTUs huggingface dataset:
An Effective QoS Control Scheme for Ubiquitous Services based on Context Information Management

In this paper, we propose a scheme to increase the QoS (quality of service) in ubiquitous computing environment by managing context information effectively where computational and network resources are limited. This novel scheme consists of a following distinguished feature: (Sl)flexible QoC (quality of context information) Control. This scheme can manage the context information based on relationship between QoC and QoS. By employing this scheme, we can avoid degradation of available network bandwidth and computational resource due to supplying excessive context information. Quality and function of overall system are also expected to be maintained while circulating context information in high quality.
Outcomes and alternative techniques for device closure of the large secundum atrial septal defect

Outcomes of device closure of large and small secundum atrial septal defects (ASDs) as related to rim anatomy with the Amplatzer atrial septal occluder were compared. Rim adequacy (≥ 5mm) of the anterior, inferior, posterior, and superior rims was determined using transesophageal echocardiography. Balloon‐stretched defect size defined patients into two groups: group 1, ≤ 25 mm (n = 138); group 2, > 25 mm (n = 34). Rim deficiency (n = 62) was more frequent in group 2 compared to group 1 (50% vs. 33%; P = 0.07), especially inferior rim deficiency (35% vs. 2%; P = 0.005). Device deployment was successful in group 1 and group 2 (100% vs. 91%; P = 0.007). Unsuccessful deployment was associated with an ASD of > 25 mm (P = 0.007) and inferior rim deficiency (P = 0.001). At first follow‐up (54 ± 16 days), right ventricular systolic pressure had improved in both groups (P < 0.001). Closure of a large ASD associated with a lack of support in the inferior rim may warrant alternative strategies to position the device successfully. Catheter Cardiovasc Interv 2004;61:131–139. © 2004 Wiley‐Liss, Inc.
Statin therapy for prevention of coronary artery disease. The earlier the better or the longer the better?

Cholesterol lowering with statin therapy has been shown to reduce cardiovascular events in a variety of patient categories, ranging from patients with established cardiovascular disease to high-risk individuals with no previous history.1 The degree of benefit relates primarily to a patient's absolute risk of cardiovascular events and to the absolute reduction in low-density lipoprotein (LDL)-cholesterol. The optimal intensity of lipid-lowering therapy has been the focus of recent clinical trials, with growing support in the cardiovascular community for the concept of ‘the lower the better’ for LDL-cholesterol. As a result, the target for LDL-cholesterol has been adjusted for patients at moderate or high risk of cardiovascular events.2 Prolonged statin treatment with a significant reduction in LDL-cholesterol has also been strongly recommended.1 Sever and colleagues have presented the results of a 2-year extension of the Anglo-Scandinavian Cardiac Outcomes Trial lipid-lowering arm (ASCOT-LLA Extension). 3 In the initial ASCOT trial, the blood pressure-lowering arm (ASCOT-BPLA) compared the effect of two different antihypertensive regimens on cardiovascular outcomes. ASCOT-LLA … *Corresponding author. Tel: +47 2307 1246, Fax: +47 2307 1247. Email : Hallvard.Holdaas{at}rikshospitalet.no
Fast deterministic construction of static dictionaries

we consider the problem of constructing a static dictionary that supports access queries for a set of w-bit keys on a wbit RAM with an arithmetic instruction set consisting of addition, subtraction, multiplication, left and right shift, and bitwise boolean operations. We show that a static dictionary for n > 4 keys that occupies O(n) space and allows queries to be processed in O(loglog r-r) time can be constructed deterministically in O(n log n) time. No previous deterministic linear-space solution simultaneously achieved o(c) query time and n’+‘(‘) construction time. The actual result is more general and allows the query time to be lowered at the cost of increasing the construction time. We also apply known dynamization techniques ‘to derive a deterministic dynamic dictionary with a tradeoff between query time and update time.
A New Transport Protocol for High(cid:1)speed Networks

The quantum increase in transmission speed of optical (cid:0)bre networks has created a bottleneck in transport protocol processing at host systems(cid:1) In this paper we present a new transport protocol system(cid:2) HTPNET(cid:2) that is designed to overcome this protocol processing bottleneck(cid:1) HTPNET is based on a highly parallel architecture and is designed to exploit the evolving char(cid:3) acteristics of high(cid:3)speed networks(cid:1) HTPNET uses an out(cid:3)of(cid:3)band signalling system based upon transmitter(cid:3)paced periodic exchanges of state information between end systems(cid:1) This mechanism exhibits several attractive properties which have been demonstrated to perform e(cid:4)ciently in a high(cid:3)speed envi(cid:3) ronment with high(cid:3)bandwidth(cid:3)delay(cid:3)product(cid:1) A prototype implementation of HTPNET has been constructed from a network of T(cid:5)(cid:6)(cid:6) transputers(cid:1) The results obtained from this implementation are presented(cid:7) these demonstrate the advantages of exploiting a parallel architecture for protocol processing(cid:1) E(cid:0)mail(cid:1)
Research on the Security Monitoring of the Amusement Ride of Tourist Sites Based on RFID

RFID (Radio Frequency Identification) is a new technology making use of radio frequency to do non-touch- ing, two-way data transit between the reader and the electronic tag to identify target and exchange data. Because it is non-touching; it can work from long distance; it is fit to work in an unfavorable environment; it can identify moving target, it is widely used in industry, commerce, storage, transportation. This paper introduces the application of the RFID technology and its state of development and discusses the general situation of its application in different fields. Moreover, this paper takes the tourist mini-train as an example, designs a security monitoring system based on RFID and discusses its application in tourist industry.
Uniqueness of de Sitter space

All inextendible null geodesics in four-dimensional de Sitter space dS4 are complete and globally achronal. This achronality is related to the fact that all observer horizons in dS4 are eternal, i.e. extend from future infinity all the way back to past infinity . We show that the property of having a null line (inextendible achronal null geodesic) that extends from to characterizes dS4 among all globally hyperbolic and asymptotically de Sitter spacetimes satisfying the vacuum Einstein equations with positive cosmological constant. This result is then further extended to allow for a class of matter models that includes perfect fluids.
Cyclic AMP Enhances TGFβ Responses of Breast Cancer Cells by Upregulating TGFβ Receptor I Expression

Cellular functions are regulated by complex networks of many different signaling pathways. The TGFβ and cAMP pathways are of particular importance in tumor progression. We analyzed the cross-talk between these pathways in breast cancer cells in 2D and 3D cultures. We found that cAMP potentiated TGFβ-dependent gene expression by enhancing Smad3 phosphorylation. Higher levels of total Smad3, as observed in 3D-cultured cells, blocked this effect. Two Smad3 regulating proteins, YAP (Yes-associated protein) and TβRI (TGFβ receptor 1), were responsive to cAMP. While YAP had little effect on TGFβ-dependent expression and Smad3 phosphorylation, a constitutively active form of TβRI mimicked the cAMP effect on TGFβ signaling. In 3D-cultured cells, which show much higher levels of TβRI and cAMP, TβRI was unresponsive to cAMP. Upregulation of TβRI expression by cAMP was dependent on transcription. A proximal TβRI promoter fragment was moderately, but significantly activated by cAMP suggesting that cAMP increases TβRI expression at least partially by activating TβRI transcription. Neither the cAMP-responsive element binding protein (CREB) nor the TβRI-regulating transcription factor Six1 was required for the cAMP effect. An inhibitor of histone deacetylases alone or together with cAMP increased TβRI expression by a similar extent as cAMP alone suggesting that cAMP may exert its effect by interfering with histone acetylation. Along with an additive stimulatory effect of cAMP and TGFβ on p21 expression an additive inhibitory effect of these agents on proliferation was observed. Finally, we show that mesenchymal stem cells that interact with breast cancer cells can simultaneously activate the cAMP and TGFβ pathways. In summary, these data suggest that combined effects of cAMP and TGFβ, as e.g. induced by mesenchymal stem cells, involve the upregulation of TβRI expression on the transcriptional level, likely due to changes in histone acetylation. As a consequence, cancer cell functions such as proliferation are affected.
Opportunistic Spectrum Access in Fading Channels Through Collaborative Sensing

Spectrum scarcity is becoming a major issue for service providers interested in either deploying new services or enhancing the capacity for existing applications. On the other hand, recent measurements suggest that many portions of the licensed (primary) spectrum remain unused for significant periods of time. This has led the regulatory bodies to consider opening up under-utilized licensed frequency bands for opportunistic access by unlicensed (secondary) users. Among different options, sensing-based access incurs a very low infrastructure cost and is backward compatible with the legacy primary systems. In this paper, we investigate the effect of user collaboration on the performance of sensing-based secondary access in fading channels. In particular, we demonstrate that under independent fading or shadowing, a low-overhead collaboration scheme with a very simple detector as its building block, 1) improves the spectrum utilization significantly, 2) enables the individual users to employ less sensitive detectors, thereby allowing a wider range of devices to access the primary bands, 3) increases the robustness toward noise uncertainty, 4) reduces the time and bandwidth resources required for satisfactory sensing which translates into higher agility and efficiency of the secondary access.
Arabidopsis GROWTH-REGULATING FACTOR7 Functions as a Transcriptional Repressor of Abscisic Acid– and Osmotic Stress–Responsive Genes, Including DREB2A[W]

Arabidopsis thaliana GROWTH-REGULATING FACTOR7 (GRF7) was identified as a transcriptional repressor of DEHYDRATION-RESPONSIVE ELEMENT-BINDING PROTEIN2A and other osmotic stress–responsive genes under normal growth conditions. This work proposes a mechanism in which GRF7 minimizes adverse effects on plant growth by repressing the expression of stress-responsive genes under favorable conditions. Arabidopsis thaliana DEHYDRATION-RESPONSIVE ELEMENT BINDING PROTEIN2A (DREB2A) functions as a transcriptional activator that increases tolerance to osmotic and heat stresses; however, its expression also leads to growth retardation and reduced reproduction. To avoid these adverse effects, the expression of DREB2A is predicted to be tightly regulated. We identified a short promoter region of DREB2A that represses its expression under nonstress conditions. Yeast one-hybrid screening for interacting factors identified GROWTH-REGULATING FACTOR7 (GRF7). GRF7 bound to the DREB2A promoter and repressed its expression. In both artificial miRNA-silenced lines and a T-DNA insertion line of GRF7, DREB2A transcription was increased compared with the wild type under nonstress conditions. A previously undiscovered cis-element, GRF7-targeting cis-element (TGTCAGG), was identified as a target sequence of GRF7 in the short promoter region of DREB2A via electrophoretic mobility shift assays. Microarray analysis of GRF7 knockout plants showed that a large number of the upregulated genes in the mutant plants were also responsive to osmotic stress and/or abscisic acid. These results suggest that GRF7 functions as a repressor of a broad range of osmotic stress–responsive genes to prevent growth inhibition under normal conditions.
Amharic Speech Recognition : Past , Present and Future

Automatic Speech Recognition (ASR) is a field which has been and being researched for more than half a century for languages like English. However, attempts in this area for Ethiopian languages, in general and Amharic, in particular started only recently. This paper, pinpoints what has been done so far and current research projects, and brings the remaining research and project ideas to the attention of researchers and developers in the field.
The semantics and pragmatics of belief reports in preschoolers

Children under 4 years have been claimed to lack adult-like semantic representations of belief verbs like 'think'. Based on two experiments involving a truth-value judgment task, we argue that 4-year olds' apparently deviant interpretations arise from pragmatic difficulty understanding the relevance of belief, rather than from conceptual or semantic immaturity.
Phosphatidylethanol (PEth) as a biomarker of alcohol consumption in HIV-positive patients in sub-Saharan Africa.

BACKGROUND Alcohol is heavily consumed in sub-Saharan Africa and affects HIV transmission and treatment and is difficult to measure. Our goal was to examine the test characteristics of a direct metabolite of alcohol consumption, phosphatidylethanol (PEth). METHODS Persons infected with HIV were recruited from a large HIV clinic in southwestern Uganda. We conducted surveys and breath alcohol concentration (BRAC) testing at 21 daily home or drinking establishment visits, and blood was collected on day 21 (n = 77). PEth in whole blood was compared with prior 7-, 14-, and 21-day alcohol consumption. RESULTS (i) The receiver operator characteristic area under the curve (ROC-AUC) was highest for PEth versus any consumption over the prior 21 days (0.92; 95% confidence interval [CI]: 0.86 to 0.97). The sensitivity for any detectable PEth was 88.0% (95% CI: 76.0 to 95.6) and the specificity was 88.5% (95% CI: 69.8 to 97.6). (ii) The ROC-AUC of PEth versus any 21-day alcohol consumption did not vary with age, body mass index, CD4 cell count, hepatitis B virus infection, and antiretroviral therapy status, but was higher for men compared with women (p = 0.03). (iii) PEth measurements were correlated with several measures of alcohol consumption, including number of drinking days in the prior 21 days (Spearman r = 0.74, p < 0.001) and BRAC (r = 0.75, p < 0.001). CONCLUSIONS The data add support to the body of evidence for PEth as a useful marker of alcohol consumption with high ROC-AUC, sensitivity, and specificity. Future studies should further address the period and level of alcohol consumption for which PEth is detectable.
Furanyl-Rhodanines Are Unattractive Drug Candidates for Development as Inhibitors of Bacterial RNA Polymerase

ABSTRACT Previous studies suggest that furanyl-rhodanines might specifically inhibit bacterial RNA polymerase (RNAP). We further explored three compounds from this class. Although they inhibited RNAP, each compound also inhibited malate dehydrogenase and chymotrypsin. Using biosensors responsive to inhibition of macromolecular synthesis and membrane damaging assays, we concluded that in bacteria, one compound inhibited DNA synthesis and another caused membrane damage. The third rhodanine lacked antibacterial activity. We consider furanyl-rhodanines to be unattractive RNAP inhibitor drug candidates.
A novel active T-type three-level converter with open-circuit fault-tolerant control

This paper proposes a novel active T-type three-level converter concept with fault-tolerant control. With the proposed topology, the converter can be operated continuously under open-circuit faults. It is shown that the proposed topology not only can keep its outputs under open-circuit fault condition without degradation of performance but can also reduce the thermal stresses in neutral-point power devices by redundant current path. The junction temperature reduction in the neutral-point devices could improve the lifetime of the system under some operating conditions especially when the neutral-point devices have the highest thermal stresses. The feasibility and effectiveness of the proposed topology concept are verified by the simulation results.
An ultra-low power charge-pump PLL with high temperature stability in 130 nm CMOS

An ultra-low power fully-integrated frequency synthesizer was designed and implemented in 130 nm CMOS technology. Based on integer-N phase locked loop architecture, the frequency synthesizer operates from 13.8 to 61 MHz. Current consumption has been minimized by the use of a mix of analog and digital blocks and a prior planning of current distribution amongst each blocks. The measured phase noise is -89.6 dBc/Hz @ 500 kHz offset and the current consumption is 77μA from 1.2V supply at 32MHz output. The reference frequency of 1MHz is generated from an on-chip RC based oscillator whose output frequency varies by only ±0.025% when temperature varies between -10°C to 110°C.
The Investment Game under Uncertainty: An Analysis of Equilibrium Values in the Presence of First or Second Mover Advantage

AbstractIn this paper we develop a valuation model when there exist two competitive firms that face irreversible investment decisions under the demand uncertainty. We propose a numerical procedure to derive both project values and equilibrium strategies in the duopolistic environment. In numerical examples we consider two different economic conditions, which are labelled first mover advantage and second mover advantage, and examine the effects of these conditions on the equilibrium strategies as well as the project values. We show that these conditions cause significant changes in the equilibrium strategies of both firms.
PENGARUH KINERJA GURU TERHADAP MOTIVASI BELAJAR SISWA

Abstrak: Pengaruh Kinerja Guru terhadap Motivasi Belajar Siswa. Penelitian ini bertujuan untuk mengungkap (1) tingkat kinerja guru IPS SMP Muhammadiyah Purworejo; (2) motivasi belajar siswa; dan (3) pengaruh kinerja guru terhadap motivasi belajar siswa SMP Muhammadiyah Purworejo. Populasi penelititian seluruh siswa SMP Muhammadiyah Purworejo. Sampel diambil menggunakan teknik stratified random sampling. Instrumen pengumpulan data menggunakan angket tertutup. Data dianalisis menggunakan korelasi parsial dan regresi. Hasil analisis menunjukkan bahwa kinerja guru 61,5 % tergolong baik (61,5%) sedangkan motivasi belajar siswa termasuk kategori tinggi (48,5%). Hasil analisis inferensial dengan menggunakan regresi diperoleh koefisien determinan (R ) sebesar 0.353 (F = 13.508 sig = 0.000 <0.05). Kata Kunci: kinerja guru, motivasi belajar, ilmu pengetahuan sosial 2 Abstract: The Influence of Teachers’ Performance on Students’ Learning Motivation. This study attempted to reveal: (1) the performance of Social Studies teachers at SMP Muhammadiyah Purworejo; (2) the students’ learning motivation; and (3) the influence of the teachers’ performance on students’ learning motivation. The population was all students of SMP Muhammadiyah Purworejo. The sample was taken using the stratified random sampling technique. The data, analyzed using the partial correlation and regression analyses, were collected using the close-ended questionnaire. The findings showed that the teachers’ performance belonged to good category (61.5%) while the students’ learning motivation was in the high category (48.5%). The regression analysis showed that the determinant coefficient (R 2 ) was 0.353 (F = 13.508 sig = 0.000 <0.05). Keywords: teachers’ performance, learning motivation, social studies
Please Scroll down for Article the Quarterly Journal of Experimental Psychology Movements or Targets: What Makes an Action in Action-effect Learning?

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Drosophila melanogaster as a model system for human brain cancers

Glioblastomas (GBM), the most common primary brain tumors, infiltrate the brain, grow rapidly, and are refractory to current therapies. Signature genetic lesions in glioblastomas include mutation of the epidermal growth factor receptor tyrosine kinase (EGFR) receptor tyrosine kinase and activating mutations in components of the PI‐3 kinase (PI3K) pathway. Despite years of study, how these pathways specifically regulate glial pathogenesis is unclear. To address the genetic and cellular origins of this disease, a novel Drosophila GBM model has been developed in which glial progenitor cells give rise to proliferative and invasive neoplastic cells that create transplantable tumors in response to constitutive co‐activation of the EGFR‐Ras and PI3K pathways. Standing with a rich literature demonstrating the direct relevance of Drosophila to studies on human cancer, neurological disease, and neurodevelopment, this model represents a robust cell‐type specific Drosophila neurological disease model in which malignant cells are created by mutations in genetic pathways thought to be driving forces in a homologous human disease. Using lineage analysis and cell‐type specific markers, neoplastic glial cells were found to originate from committed glial progenitor cells, rather than from multipotent neuroblasts. Genetic analyses demonstrated that EGFR‐Ras and PI3K induce fly glial neoplasia through activation of a combinatorial genetic network composed, in part, of other genetic pathways also commonly mutated in human glioblastomas. In the future, large‐scale forward genetic screens with this model may reveal new insights into the origins and treatments of human glioblastoma. © 2011 Wiley‐Liss, Inc.
Adaptive current control for grid-connected converters with LCL-filter

This paper presents a discrete-time adaptive current controller for grid-connected voltage source PWM converters with LCL-filter. The main attribute of the proposed current controller is that, in steady state, the damping of the LCL resonance does not depend on the grid characteristic since the adaptive feedback gains ensure a predefined behavior for the closed-loop current control. Simulation and experimental results are presented to validate the analysis and to demonstrate the good performance of the proposed controller for grid-connected converters subjected to large grid impedance variation and grid voltage disturbances.