Miracle-dz/UniFAR-FTUs huggingface dataset:
A novel design for content delivery over software defined mobile social networks

With the rapid development of mobile communication technologies, various kinds of content can be delivered among mobile users for content sharing. Due to the complexity of networks and particular features of mobile behaviors, to manage networks efficiently, SDMSNs are advocated where the control plane and data plane can work separately but cooperatively. In this article we outline how to deliver mobile content over SDMSNs. We first design the flow table based on the social features including social tie, mobility, and community. Then a novel social switch is introduced to deliver content among mobile users by using the proposed social degree and social stay time. In addition, the process of content delivery is presented according to different scenarios, and extensive experiments are given to prove the efficiency of this approach.
Grieving, Mourning, and Healing Following Youth Suicide: A Focus on Health and Well Being in Families

Within the context of their grieving families, this grounded theory study explored survivors' experiences of healing following youth suicide. The major theme developed in this study, Journeying Toward Wholeness, is conceptualized as a process involving the inter-relationships among three sub-themes: Grieving in Response to Youth Suicide, Mourning in Response to Youth Suicide, and Healing in Response to Youth Suicide. Initially, grieving, mourning, and healing occur within individual and family realms. Theoretically congruent with systems theory, this mid-range grounded theory suggests that grieving, mourning, and healing are embedded within a broader social context. This theory purports that grieving, mourning, and healing are related, dynamic, and seamless processes influencing each person's journey toward wholeness following youth suicide. This theory supplements the basis of holistic practice, directs us to accept a broad range of survivors' expressions of movement towards wholeness and health, stresses the importance of working with survivors' stories, and encourages us in relational practice.
SportsMedUpdate

Methodology: Subjects: Seven healthy subjects (19–41 years)(male = 4, female = 3) Experimental procedure: All the subjects were assessed and then tested in a laboratory where changes in tendon force and length changes were determined (utilising a combination of motion analysis, force plate data, electromyographic data and real-time ultrasound data) during eccentric (ECC) and concentric (CONC) loading exercises of the Achilles tendon. Measures of outcome: Peak tendon force (N), tendon length (change), frequency of oscillations in tendon force (inflections per cycle)
Ultrastructure of antennal sensilla of four skipper butterflies in Parnara sp. and Pelopidas sp. (Lepidoptera, Hesperiidae)

Abstract Most species of Parnara and Pelopidas (Hesperiidae) are important pests of rice. In this study, the antennal morphology, types of sensilla, and their distribution of four skipper butterflies, including Parnara guttata (Bremer & Grey), Pa. bada (Moore), Pelopidas mathias (Fabricius) and Pe. agna (Moore), were observed using a scanning electron microscope. Six distinct morphological types of sensilla were found on the antennae of all of these species: sensilla squamiformia, sensilla trichodea, sensilla chaetica, sensilla auricillica, sensilla coeloconica, and Böhm sensilla. The sensilla trichodea are the most abundant sensilla among the four skipper butterflies, and the sensilla auricillica are confirmed on the antennae of butterflies for the second time. In addition, the possible functions of these sensilla are discussed in the light of previously reported lepidopteran insects, which may provide useful information for further study of the function of these antennal sensilla and for related pests control by applying sex pheromones.
9-1-1 DDoS: Attacks, Analysis and Mitigation

The 911 emergency service belongs to one of the 16 critical infrastructure sectors in the United States. Distributed denial of service (DDoS) attacks launched from a mobile phone botnet pose a significant threat to the availability of this vital service. In this paper we show how attackers can exploit the cellular network protocols in order to launch an anonymized DDoS attack on 911. The current FCC regulations require that all emergency calls be immediately routed regardless of the caller's identifiers (e.g., IMSI and IMEI). A rootkit placed within the baseband firmware of a mobile phone can mask and randomize all cellular identifiers, causing the device to have no genuine identification within the cellular network. Such anonymized phones can issue repeated emergency calls that cannot be blocked by the network or the emergency call centers, technically or legally. We explore the 911 infrastructure and discuss why it is susceptible to this kind of attack. We then implement different forms of the attack and test our implementation on a small cellular network. Finally, we simulate and analyze anonymous attacks on a model of current 911 infrastructure in order to measure the severity of their impact. We found that with less than 6K bots (or $100K hardware), attackers can block emergency services in an entire state (e.g., North Carolina) for days. We believe that this paper will assist the respective organizations, lawmakers, and security professionals in understanding the scope of this issue in order to prevent possible 911-DDoS attacks in the future.
Departmental Leadership and Management in Chartered and Statutory Universities

This article presents the findings of two case studies of leadership and management in engineering departments in two British universities, one a chartered university and one a statutory university. The studies are the first in a series of ‘pairs’ of such studies in departments of various academic discipline and size, in the two types of university. Data were collected by semi-structured interviews with the heads of the two departments and members of their staff who have leadership and/or management roles. The most striking feature of the study is the very different cultures and organizational structures of the two departments and their very different approaches to leadership and management. The studies also raises questions regarding the findings of other researches and writings, namely that heads of department have unreasonably high workloads, that large university departments are difficult to manage and that collegiality is the preferred model of decision-making
Genome Sequence of Salmonella Phage 9NA

ABSTRACT The virulent double-stranded DNA (dsDNA) bacteriophage 9NA infects Salmonella enterica serovar Typhimurium and has a long noncontractile tail. We report its complete 52,869-bp genome sequence. Phage 9NA and two closely related S. enterica serovar Newport phages represent a tailed phage type whose molecular lifestyle has not yet been studied in detail.
Towards Effective Web Resources Management An Empirical Study and a Web Mining Approach

The unpredictable workload generated by surfers on an electronic commerce (EC) site poses challenges to Web sites maintenance. Proactive maintenance on Web site is important. This depends much on how to best characterize its workload profile. An EC site would consist of a list of core EC processes, the demand on these EC functions forecast is critical for sustaining the site performance within the service level agreements (SLA). The service demand of on-line functions determines the resources utilization that supports the operations. In e-market, online companies must meet customers' expectation on quality of services (QoS) to sustain its profit. This paper attempts to propose a model to proactively anticipating performance problems with the waves of changing customers' demand. A Web mining approach is applied on the server's log file of an empirical Web site. The resulting knowledge would foster the development of better management on Web resources of EC sites
The Social and Geographic Patterns of Sexual Offending: Is Sex Offender Residence Restriction Legislation Practical?

Abstract The development of sex offender residence restriction legislation was predicated on the assumption that sex offenders pose an increased risk to the public. The goal of such legislation was to create “sex-offender-free” zones in an effort to decrease sex offenders’ access to potential victims. Such legislation prohibits registered sex offenders from residing near landmarks where children are known to congregate. Empirical evidence thus far has failed to demonstrate that residing near these landmarks contributes to sex offenders’ ability to access victims, and may actually be doing more harm than good. The current study questions the rationale behind the implementation of residence restrictions and if this rationale is consistent with the realities of victim selection and sexual offending among incarcerated sex offenders. The sample consisted of 270 males incarcerated in a New Jersey correctional facility. The results demonstrate that most sex offenders resided within a 2,500-foot restricted landmark zone. However, after examining the methods sex offenders used and examining how far they traveled to meet or establish contact with their victims, residing near restricted landmarks did not contribute to victim selection. Of the 270 sex offenders, the offense patterns consistent with many residence restrictions were applicable to less than 1%.
Classification of the state-of-the-art dynamic web services composition techniques

Dynamic web service composition can serve applications or users on an on-demand basis. With dynamic composition, the application's capabilities can be extended at runtime so that theoretically an unlimited number of new services can be created from a limited set of service components, thus making applications no longer restricted to the original set of operations specified and envisioned at design and/or compile time. Moreover, dynamic composition is the only means to adapt the behaviour of running components in highly available applications such as, banking and telecommunication systems where services cannot be brought offline to upgrade or remove obsolete services. In this paper, we present a novel classification of the current state-of-the-art dynamic web services composition techniques with attention to the capabilities and limitations of the underlying approaches. The proposed taxonomy of these techniques is derived based on a comprehensive survey of what has been done so far in dynamic web service composition. Finally, we summarise our findings and present a vision for future research work in this area.
Tissue Specific Profiling of Females of Schistosoma japonicum by Integrated Laser Microdissection Microscopy and Microarray Analysis

Background The functions of many schistosome gene products remain to be characterized. A major step towards elucidating function of these genes would be in defining their sites of expression. This goal is rendered difficult to achieve by the generally small size of the parasites and the lack of a body cavity, which precludes analysis of transcriptional profiles of the tissues in isolation. Methodology/Principal Findings Here, we describe a combined laser microdissection microscopy (LMM) and microarray analysis approach to expedite tissue specific profiling and gene atlasing for tissues of adult female Schistosoma japonicum. This approach helps to solve the gene characterization “bottle-neck” brought about by acoelomy and the size of these parasites. Complementary RNA obtained after isolation from gastrodermis (parasite gut mucosa), vitelline glands and ovary by LMM were subjected to microarray analyses, resulting in identification of 147 genes upregulated in the gastrodermis, 4,149 genes in the ovary and 2,553 in the vitellaria. Conclusions This work will help to shed light on the molecular pathobiology of this debilitating human parasite and aid in the discovery of new targets for the development of anti-schistosome vaccines and drugs.
Emotion, motivation, and reward processing in schizophrenia spectrum disorders: what we know and where we need to go.

Theorists and researchers on schizophrenia spectrum disorders have long recognized the central role that emotional processing may play in these illnesses since the times of Bleuler and Kraepelin.1,2 For example, our current diagnostic criteria for schizophrenia include reference to disturbances in a number of different aspects of emotional processing, including the ability to display affect either facially or vocally, the ability to display emotions that are deemed appropriate to the current context, and the ability to experience or anticipate pleasure. Further, clinicians have long noted the importance of negative mood and depression in understanding function, course, and outcome in this illness. However, despite the centrality of various aspects of emotional processing in several theories of the development of schizophrenia,3–6 there is a surprising dearth of empirical work examining emotion and motivation in schizophrenia, particularly when one considers the huge body of work on other aspects of the illness, such as cognition, hallucinations, and delusions. The need for more empirical data in this regard has recently been recognized in a number of initiatives, including an offshoot of the Measurement and Treatment Research To Improve Cognition in Schizophrenia initiative that has emphasized the importance of more empirical work on negative symptoms in schizophrenia,7,8 which include abnormalities in various aspects of emotional and motivational processing.
Spectrum of eleven-dimensional supergravity on a pp -wave background

We calculate the spectrum of the linearized supergravity around the maximally supersymmetric pp-wave background in eleven dimensions. The resulting spectrum agrees with that of zero-mode Hamiltonian of a supermembrane theory on the pp-wave background. We also discuss the connection with the Kaluza-Klein zero modes of an ${\mathrm{AdS}}_{4}\ifmmode\times\else\texttimes\fi{}{\mathrm{S}}^{7}$ background.
500 °C High Current 4H-SiC Lateral BJTs for High-Temperature Integrated Circuits

High-current 4H-SiC lateral BJTs for high-temperature monolithic integrated circuits are fabricated. The BJTs have three different sizes and the designs are optimized in terms of emitter finger width and length and the device layout to have higher current density (J<sub>C</sub>), lower on-resistance (R<sub>ON</sub>), and more uniform current distribution. A maximum current gain (<inline-formula> <tex-math notation="LaTeX">$\beta $ </tex-math></inline-formula>) of >53 at significantly high current density was achieved for different sizes of SiC BJTs. The BJTs are measured from room temperature to 500 °C. An open-base breakdown voltage (V<sub>CEO</sub>) of >50 V is measured for the devices.
Antiapoptotic Activity of Autocrine Interleukin-22 and Therapeutic Effects of Interleukin-22-Small Interfering RNA on Human Lung Cancer Xenografts

Purpose: Non–small cell lung carcinoma (NSCLC) is one of most common malignant diseases and usually is resistant against apoptosis-inducing chemotherapy. This study is to explore the antiapoptotic mechanisms of interleukin (IL)-22 in human lung cancer. Experimental Design: Nineteen cases with stage I to III NSCLC were collected to determine the expression of IL-22. Stable transfection of human IL-22 cDNA into A549 and PG cells and transfection of IL-22-RNA interference (RNAi) into these cancer cell lines were done to reveal the molecular mechanisms of IL-22. Results: It was found that IL-22 was highly expressed in primary tumor tissue, malignant pleural effusion, and serum of patients with NSCLC. IL-22R1 mRNA was also detected in lung cancer tissues as well as lung cancer cell lines. Overexpression of IL-22 protected lung cancer cell lines from serum starvation-induced and chemotherapeutic drug-induced apoptosis via activation of STAT3 and its downstream antiapoptotic proteins such as Bcl-2 and Bcl-xL and inactivation of extracellular signal-regulated kinase 1/2. Exposure to blocking antibodies against IL-22R1 or transfection with the IL-22-RNAi plasmid in vitro resulted in apoptosis of these lung cancer cells via STAT3 and extracellular signal-regulated kinase 1/2 pathways. Furthermore, an in vivo xenograft study showed that administration of IL-22-RNAi plasmids significantly inhibited the human tumor cell growth in BALB/c nude mice. Conclusions: Our study indicates that autocrine production of IL-22 contributes to human lung cancer cell survival and resistance to chemotherapy through the up-regulation of antiapoptotic proteins.
Targeted therapy with the T-cell-engaging antibody blinatumomab of chemotherapy-refractory minimal residual disease in B-lineage acute lymphoblastic leukemia patients results in high response rate and prolonged leukemia-free survival.

PURPOSE Blinatumomab, a bispecific single-chain antibody targeting the CD19 antigen, is a member of a novel class of antibodies that redirect T cells for selective lysis of tumor cells. In acute lymphoblastic leukemia (ALL), persistence or relapse of minimal residual disease (MRD) after chemotherapy indicates resistance to chemotherapy and results in hematologic relapse. A phase II clinical study was conducted to determine the efficacy of blinatumomab in MRD-positive B-lineage ALL. PATIENTS AND METHODS Patients with MRD persistence or relapse after induction and consolidation therapy were included. MRD was assessed by quantitative reverse transcriptase polymerase chain reaction for either rearrangements of immunoglobulin or T-cell receptor genes, or specific genetic aberrations. Blinatumomab was administered as a 4-week continuous intravenous infusion at a dose of 15 μg/m2/24 hours. RESULTS Twenty-one patients were treated, of whom 16 patients became MRD negative. One patient was not evaluable due to a grade 3 adverse event leading to treatment discontinuation. Among the 16 responders, 12 patients had been molecularly refractory to previous chemotherapy. Probability for relapse-free survival is 78% at a median follow-up of 405 days. The most frequent grade 3 and 4 adverse event was lymphopenia, which was completely reversible like most other adverse events. CONCLUSION Blinatumomab is an efficacious and well-tolerated treatment in patients with MRD-positive B-lineage ALL after intensive chemotherapy. T cells engaged by blinatumomab seem capable of eradicating chemotherapy-resistant tumor cells that otherwise cause clinical relapse.
Espace et sacralité

L’espace sacre, en Europe, s’inscrit dans un paysage. Il y a par exemple un paysage catholique classique, familier, que l’on retrouve dans des pays comme l’Espagne, la France et l’Italie : le clocher qui emerge des toits du village, rassembles autour de l’eglise comme le troupeau autour du berger. Anciennement, et il existe encore des traces de cette organisation, les tombes des morts entouraient l’eglise comme pour rendre encore plus visible la communaute des chretiens. On peut faire trois r.
Gestão do Conhecimento e Redesenho de Processos de Negócio: Proposta de uma Metodologia Integrada

In the last decade, several Knowledge Management (KM) frameworks have been developed and applied to improve creation, storage, transfer and reuse of knowledge. However, a number of projects have failed to generate the expected benefits due to a gap between KM activities and those that constitute the routines of an organization, as defined in its business processes. This paper draws on the idea that the association of KM practices and organizational routines is essential to companies success nowadays to put forth an integrated process redesign and knowledge management methodology. With this goal, some of the foremost KM frameworks were analyzed to identify the tasks that are essential to the effective management of organizational knowledge. Then, the compatibility between such tasks and the procedures defined by major process redesign methodologies were evaluated. This analysis supported the elaboration of a revised methodology that integrates the principles and techniques of both types of initiatives. The adoption of the proposed methodology should elicit the creation of business processes that harmonize an efficient, low cost operation and the systematization of an organizations knowledge creation, storage, transfer and reuse activities.
In vitro susceptibility studies of vancomycin-resistant Enterococcus faecalis

Vancomycin resistance exhibited by Enterococcus faecalis isolates V583, V586, and V587 is described. The vancomycin MICs ranged from 32 to 64 micrograms/ml. Although resistant to vancomycin, the isolates were susceptible to teicoplanin (MIC, less than or equal to 0.5 micrograms/ml). Such a glycopeptide susceptibility profile has not been previously described for E. faecalis. Time kill studies showed that vancomycin resistance adversely affected the synergistic activity that vancomycin and aminoglycoside combinations usually demonstrate against enterococci. However, the ability to detect vancomycin resistance varied with the susceptibility testing method used. Whereas broth microdilution, broth macrodilution, and agar dilution methods detected resistance, disk-agar diffusion and the AutoMicrobic system Gram-Positive GPS-A susceptibility card (Vitek Systems Inc., Hazelwood, Mo.) did not. To detect vancomycin resistance reliably and establish the incidence of such E. faecalis isolates, adjustments in some susceptibility testing methods may be necessary.
Tight GNSS/INS integration as a constrained least-squares problem

In this paper, we study a new GNSS/INS tight integration algorithm. The underlying idea is to obtain user's position as the solution to a constrained version of the GNSS optimization problem, where classical trilateralization is constrained by INS measurements. This leads to a linearly constrained least-squares problem that can be efficiently solved in worst-case polynomial time. The performance of the algorithm has been validated through simulations under challenging scenarios (namely, multipath and weak signal conditions), showing an improved performance w.r. t. GNSS stand-alone and GNSS/INS Kalman filter solutions under the same conditions.