Miracle-dz/UniFAR-FTUs huggingface dataset:
Automated Model Selection in Finance: General-to-Speciflc Modelling of the Mean, Variance and Density ⁄

General-to-Speciflc (GETS) modelling has witnessed major advances over the last decade thanks to the automation of multi-path GETS speciflcation search. However, several scholars have argued that the estimation complexity associated with flnancial models constitutes an obstacle to multi-path GETS modelling in flnance. Making use of a recent result on log-GARCH Models, we provide methods and develop a simple but general and ∞exible algorithm that automates flnancial multi-path GETS modelling. Starting from a general model where the mean speciflcation can contain autoregressive (AR) terms and explanatory variables, and where the exponential variance speciflcation can include log-ARCH and log-GARCH terms, an asymmetry term, Bernoulli jumps and other explanatory variables, the algorithm we propose returns parsimonious mean and variance speciflcations, and a fat-tailed distribution of the standardised error if normality is rejected. The flnite sample properties of the methods and of the algorithm are studied by means of extensive Monte Carlo simulations, and three empirical applications suggest the methods and algorithm are very useful in practice.
A Dissociation of Motion and Spatial-Pattern Vision in the Avian Telencephalon: Implications for the Evolution of “Visual Streams”

The ectostriatum is a large visual structure in the avian telencephalon. Part of the tectofugal pathway, the ectostriatum receives a large ascending thalamic input from the nucleus rotundus, the homolog of the mammalian pulvinar complex. We investigated the effects of bilateral lesions of the ectostriatum in pigeons on visual motion and spatial-pattern perception tasks. To test motion perception, we measured performance on a task requiring detection of coherently moving random dots embedded in dynamic noise. To test spatial-pattern perception, we measured performance on the detection of a square wave grating embedded in static noise. A double dissociation was revealed. Pigeons with lesions to the caudal ectostriatum showed a performance deficit on the motion task but not the grating task. In contrast, pigeons with lesions to the rostral ectostriatum showed a performance deficit on the grating task but not the motion task. Thus, in the avian telencephalon, there is a separation of visual motion and spatial-pattern perception as there is in the mammalian telencephalon. However, this separation of function is in the targets of the tectofugal pathway in pigeons rather than in the thalamofugal pathway as described in mammals. The implications of these findings with respect to the evolution of the visual system are discussed. Specifically, we suggest that the principle of parallel visual streams originated in the tectofugal pathway rather than the thalamofugal pathway.
Decision support for stroke rehabilitation therapy via describable attribute-based decision trees

This paper proposes a computational framework for movement quality assessment using a decision tree model that can potentially assist a physical therapist in a telereha-bilitation context. Using a dataset of key kinematic attributes collected from eight stroke survivors, we demonstrate that the framework can be reliably used for movement quality assessment of a reach-to-grasp cone task, an activity commonly used in upper extremity stroke rehabilitation therapy. The proposed framework is capable of providing movement quality scores that are highly correlated to the ratings provided by therapists, who used a custom rating rubric created by rehabilitation experts. Our hypothesis is that a decision tree model could be easily utilized by therapists as a potential assistive tool, especially in evaluating movement quality on a large-scale dataset collected during unsupervised rehabilitation (e.g., training at the home), thereby reducing the time and cost of rehabilitation treatment.
Syntactically motivated task definition for temporal relation identification

The annotation of temporal relations remains a challenge, being a very difficult task for humans, not to mention machines, to reliably and consistently annotate temporal relations in natural language texts. This paper advocates a change in the definition of the problem itself, by proposing a staged divide-and-conquer approach guided by syntax, that offers a more principled way of selecting temporal entities involved in a temporal relation. The decomposition of the problem into smaller syntactically motivated tasks, and the identification of accurate and linguistically grounded solutions to solve them, promote a sound understanding of the phenomena involved in establishing temporal relations. We illustrate the potential of linguistically informed solutions in the area of temporal relation identification by proposing and evaluating an initial set of syntactically motivated tasks. RESUME. L'annotation de relations temporelles demeure encore aujourd'hui un defi : annoter manuellement de facon fiable et coherente les relations temporelles dans des textes reste difficile et l'est bien plus encore lorsqu'il s'agit d'annotation automatique. Cet article preconise un changement dans la definition du probleme en proposant une approche qui, en s'appuyant sur la syntaxe et sur une strategie de type « diviser pour conquerir », offre une maniere plus elaboree de selectionner les entites impliquees dans une relation temporelle. La decomposition du probleme en de plus petites questions se concentrant sur la syntaxe et l'identification de solutions precises et linguistiquement fondees pour les resoudre favorisent une meilleure comprehension des phenomenes impliques dans l'etablissement de relations temporelles. Nous illustrons le potentiel des solutions linguistiquement fondees dans le cadre de l'identification de relations temporelles en proposant et evaluant une premiere serie de tâches se concentrant sur la syntaxe.
Guideline for Capsule Endoscopy: Obscure Gastrointestinal Bleeding

Capsule endoscopy (CE) is considered as a noninvasive and reliable diagnostic tool of examining the entire small bowel. CE has been performed frequently at many medical centers in South Korea; however, there is no evidence-based CE guideline for adequate diagnostic approaches. To provide accurate information and suggest correct testing approaches for small bowel disease, the guideline on CE was developed by the Korean Gut Image Study Group, a part of the Korean Society of Gastrointestinal Endoscopy. Operation teams for developing the guideline were organized into four areas: obscure gastrointestinal bleeding, small bowel preparation, Crohn's disease, and small bowel tumor. A total of 20 key questions were selected. In preparing this guideline, MEDLINE, Cochrane library, KMbase, KISS, and KoreaMed literature searches were performed. After writing a draft of the guideline, opinions from various experts were reflected before approving the final document. The guideline should be regarded as recommendations only to gastroenterologists in providing care to their patients. These are not absolute rules and should not be construed as establishing a legal standard of care. Although further revision may be necessary as new data appear, this guideline is expected to play a role for adequate diagnostic approaches of various small bowel diseases.
Left Ventricular Remodeling After Primary Coronary Angioplasty: Patterns of Left Ventricular Dilation and Long-Term Prognostic Implications

Background—We prospectively evaluated the prevalence, pattern, and prognostic impact of left ventricular (LV) remodeling after acute myocardial infarction (AMI) successfully treated with primary PTCA. The prevalence, course, and prognostic value of LV remodeling after primary PTCA are still to be clarified. Methods and Results—In 284 consecutive patients with AMI treated with primary PTCA, serial echocardiographic and angiographic studies, within 24 hours (T1), at 1 (T2) and 6 months (T3) after AMI were performed. Long-term (61±14 months) clinical follow-up data were collected for 98.6% patients enrolled in the study. Overall, 85 (30%) patients showed LV dilation (>20% end-diastolic volume increase) at T3 as compared with T1. Early (from T1 to T2), late (from T2 to T3), and progressive dilation patterns (from T1 to T2 to T3) were detected in 42 (15%), 41 (14%), and 36 (13%) patients, respectively. Cardiac death and combined events rate was significantly higher among patients with than among those without LV dilation (P =0.005 and P =0.025, respectively). The pattern of LV dilation during 6 months did not significantly affect survival. Cox survival analysis identified end-systolic volume at T1 and age as baseline predictors and end-systolic volume at T3 and age as 6-month predictors of cardiac death, respectively. Conclusions—LV remodeling after successful PTCA occurs despite sustained patency of the infarct-related artery and preservation of regional and global LV function. LV dilation at 6 months after AMI but not the specific pattern of LV dilation is clearly associated with worse long-term clinical outcome.
High-Fidelity or Low-Fidelity, Paper or Computer? Choosing Attributes when Testing Web Prototypes

Interface designs are currently tested in a mixture of fidelities and media. So far, there is insufficient research to indicate what level of fidelity and media will produce the best feedback from users. This experiment compared user testing with low- and high-fidelity prototypes in both computer and paper media. Task-based user tests of sketched (low-fidelity) and HTML (high-fidelity) website prototypes were conducted in each medium, separating the testing medium from other factors of prototype fidelity. We found that low- and high-fidelity prototypes are equally good at uncovering usability issues. Usability testing results were also found to be independent of medium, despite differences in interaction style. Designers should choose whichever medium and level of fidelity suit their practical needs and design goals, as discussed in this paper.
Exploring the Underlying Relationship between Crisis Management (CM) and Corporate Social Responsibility (CSR)

There has been a natural symbiotic relationship between crisis management issues and corporate social responsibility. This symbiotic relationship benefits consumers in being able to recognize brands and corporations that produce quality products and services. The benefit to corporations is in maintaining a positive relationship with consumers as well as internal direction for employees and management. The increasing complexity of products, increasing demands of customers, and a more observant media are crisis prevention and corporate social responsibility a more important element in strategic planning. This paper addresses some commonalities between crisis management and corporate social responsibility that can likely be a prescription for future success in strategic planning. The major findings are developed thorough the investigation of both case analysis and data from managers and non-managers in varying industries. The results of this study provide support for the premise that there is an inherent relationship between CM and CSR. In addition, we find that the product development and quality is one of the most important variables in both case analysis and among industry professionals.
ATM and ATR Substrate Analysis Reveals Extensive Protein Networks Responsive to DNA Damage

Cellular responses to DNA damage are mediated by a number of protein kinases, including ATM (ataxia telangiectasia mutated) and ATR (ATM and Rad3-related). The outlines of the signal transduction portion of this pathway are known, but little is known about the physiological scope of the DNA damage response (DDR). We performed a large-scale proteomic analysis of proteins phosphorylated in response to DNA damage on consensus sites recognized by ATM and ATR and identified more than 900 regulated phosphorylation sites encompassing over 700 proteins. Functional analysis of a subset of this data set indicated that this list is highly enriched for proteins involved in the DDR. This set of proteins is highly interconnected, and we identified a large number of protein modules and networks not previously linked to the DDR. This database paints a much broader landscape for the DDR than was previously appreciated and opens new avenues of investigation into the responses to DNA damage in mammals.
Obstetric outcome in singletons after in vitro fertilization with cryopreserved/thawed embryos.

BACKGROUND There is increasing use of cryopreservation in IVF. This study compared singletons born after cryopreservation with singletons born after fresh IVF cycles and singletons born to women in the general population. METHODS Data were collected for Swedish IVF treatments during the years 2002-2006. All singletons from single embryo transfer (SET) and double embryo transfer (DET) after cryopreserved (n = 2348) and fresh cycles (n = 8944) were included and cross-linked with the Swedish Medical Birth Registry and compared with all singletons born after spontaneous conception (n = 571 914). Main outcomes were preterm and very preterm birth and low and very low birthweight (VLBW). Other outcomes were small for gestational age, large for gestational age (LGA), perinatal mortality and maternal outcomes. RESULTS Singletons from cryopreserved SET/DET or cryopreserved SET had increased rates of extreme preterm birth compared with singletons from the general population. A lower rate of LBW was found for cryopreserved SET/DET singletons compared with singletons from fresh cycles; however, a higher rate of perinatal mortality was detected. The rates of LGA and macrosomia were increased for cryopreserved SET/DET singletons when compared with those from fresh cycles and the general population. For maternal outcomes, a higher rate of pre-eclampsia was noted for pregnancies from cryopreserved cycles compared with those from fresh cycles or the general population, but the rate of placenta praevia was lower in pregnancies from cryopreserved cycles compared with those from fresh cycles. CONCLUSIONS The obstetric outcome of singletons after cryopreservation was slightly poorer when compared with the general population. In comparison with fresh cycles, the outcome varied. The finding of an increased rate of LGA after cryopreservation requires further study.
Optimal two-dimensional variable-weight optical orthogonal codes via scarce mixed difference families

A 2-D variable-weight OOC (2-D VWOOC) is a set of 0, 1 matrices with variable weight, good auto and cross-correlations, it was first introduced to meet multiple QoS (Quality of Service) requirements in fiber optic communications. In this paper, two new infinite classes of optimal 2-D VWOOCs are constructed.
Decreased Antipyrine Clearance following Endotoxin Administration: In Vivo Evidence of the Role of Nitric Oxide

ABSTRACT Klebsiella pneumoniae endotoxin has been found to decrease hepatic P450-mediated drug-metabolizing enzyme activity in a time-dependent manner. In this study, we investigated the role of nitric oxide (NO) in the decrease in hepatic drug-metabolizing enzyme activity caused by endotoxin in vivo. We measured in vivo pharmacokinetic parameters of antipyrine in rats treated with endotoxin and/or a selective inhibitor of inducible NO synthase (iNOS),S-methylisothiourea. Intraperitoneal injection of endotoxin (1 mg/kg of body weight) dramatically decreased the systemic clearance of antipyrine, reflecting reduced hepatic drug-metabolizing enzyme activity, and significantly increased the level of nitrite and nitrate (NOx) in the plasma. S-Methylisothiourea (10 mg/kg) reversed this decreasing antipyrine clearance and reduced the level of NOx in plasma. Repeated injections of an NO donor, (±)-(E)-4-ethyl-2-[(E)-hydroxyimino]-5-nitro-3-hexenamide (FK-409; 10 mg/kg), at a dose which maintained plasma NOx at the same levels as those caused by endotoxin injection, also decreased the systemic clearance of antipyrine. These findings suggest that the overproduction of NO observed in this animal model is at least partially responsible for the significant reduction in the hepatic drug-metabolizing enzyme activity that may happen in a gram-negative bacterial infection.
Applications of two-faced processes to random number generation

Random and pseudorandom number generators (RNG and PRNG) are used for many purposes including cryptographic, modeling and simulation applications. For such applications a generated bit sequence should mimic true random, i.e., by definition, such a sequence could be interpreted as the result of the flips of a fair coin with sides that are labeled 0 and 1 (i.e., it is the Bernoulli process with p(0) = p(1) = 1/2). It is known that the Shannon entropy of this process is 1 per letter, whereas for any other stationary process with binary alphabet the Shannon entopy is stricly less than 1. On the other hand, the entropy of the PRNG output should be much less than 1 bit (per letter), but the output sequence should look like truly random. We describe random processes for which these, contradictory at first glance, properties, are valid. More precisely, it is shown that there exist binary-alphabet random processes whose entropy is less than 1 bit (per letter), but the frequency of occurrence of any word |u| goes to 2-|u|, where |u| is the length of u. In turn, it gives a possibility to construct RNG and PRNG which possess theoretical guarantees. This possibility is important for applications such as those in cryptography. We performed some experiments in which low-entropy sequences are transformed into two-faced sequences.
Biomolecular Interaction Study of Cyclolinopeptide A with Human Serum Albumin

The kinetics, energetics, and structure of Cyclolinopeptide A binding with Human Serum Albumin were investigated with surface plasmon resonance and circular dichroism. The complex is formed through slow recognition kinetics that is temperature sensitive in the range of 20°C–37°C. The overall reaction was observed to be endothermic (ΔH = 204 kJ mol−1) and entropy driven (ΔS = 746 J mol−1K−1) with overall small changes to the tertiary structure.
Energy-Efficient Distributed Compression and Error Control in Wireless Sensor Networks

This project will study distributed algorithms for signal c ompression and error control in wireless sensor networks. This is a new area, to our knowledge not previously add ressed within Wireless@KTH, even though it is tightly related to existing activities in ad hoc wireless ne tworks, relay networks and cooperative transmission. Our main motivation is energy-efficiency, to address applic ations where battery drain in the sensor nodes is a major issue. To introduce the problem we propose to study, consider the se tup illustrated in the figure below.
A new bandwidth statistical multiplexing scheme for 2D WLAN environments with passive reservations

The last studies about telecommunications and computer-science have increased the need and the availability of communication devices, such as laptops and palmtops; at the same time, the research in digital wireless communications has made possible the connection of notebooks to Internet wherever they are. Providing adequate quality of service is a very important issue in wireless communications, because of the heavy impact of userspsila mobility, especially when mobile nodes move among different coverage areas. In this paper a novel 2D passive reservation scheme for WLAN environment is presented: the cell stay time distribution is analyzed under the smooth random mobility model in terms of mean and standard deviation; then, a new prediction technique is proposed as an enhancement of previous mobility independent predictive (MIP) pre-reservation schemes, that led to an acceptable service degradation with very low system utilization. With the help of the CST statistical multiplexing introduced in this paper, better results are obtained in terms of higher system utilization, maintaining the quality of service and prediction error at acceptable levels. The proposed idea has been validated through many simulation campaigns, with a good performance analysis in terms of bandwidth utilization, prediction errors and other interesting parameters.
Chapter 5 What Genealogies of S-alleles Tell

Drawing on examples from S-RNase-based self-incompatibility (SI), Slocus genealogies are used to infer the demographic history of lineages, the history of mating-system transitions in entire plant families and aspects of the evolution of the S-locus itself. Two lineages of Solanaceae suffered severe restrictions of S-locus diversity evident after millions of years. Broadly shared ancestral S-locus polymorphism is evidence that loss of this form of incompatibility was irreversible in the Solanaceae. Frequent and irreversible loss implies incompatibility is either declining in frequency through time, or that it confers an increased diversification rate relative to self-compatibility (SC). Differences in diversification rate among self-incompatible and self-compatible lineages likely cause the failure of current phylogenetic methods to correctly reconstruct the history of SI. Genealogies also show that origination of new S-RNases rarely occurs within the lifetimes of species. Surprisingly, genealogies of F-box genes purported to provide pollen specificity often do not correspond to those of their cognate S-RNases, indicating we have much to learn about how this system works and evolves.
Méthodes numériques avancées pour la finance . — Méthodes de splitting —

où K est le prix d’exercice de l’option. Pour ce type de put, il existe une solution explicite à l’EDP (qui a valu le prix Nobel d’économie à Robert Merton et Myron Scholes en , Fischer Black étant mort en ). En revanche, ce n’est pas le cas si on complexifie cette équation pour mieux correspondre à la réalité des marchés financiers. Tout d’abord, il paraı̂t naturel de généraliser au cas d’options portant sur plusieurs actifs de valeurs s = (s1, . . . , sk) ∈ (R+)k, on alors l’équation
Imprinted silencing of Slc22a2 and Slc22a3 does not need transcriptional overlap between Igf2r and Air

Silencing of the paternal allele of three imprinted genes (Igf2r, Slc22a2 and Slc22a3) requires cis expression of the Air RNA that overlaps the promoter of one of them (Igf2r). Air is a non‐coding RNA whose mode of action is unknown. We tested the role of the Igf2r promoter and the role of transcriptional overlap between Igf2r and Air in silencing in this cluster. We analyzed imprinted expression in mice in which the Igf2r promoter is replaced by a thymidine kinase promoter that preserves a transcription overlap with Air, and in mice with a deleted Igf2r promoter that lack any transcriptional overlap with Air. Imprinted silencing of Air, Slc22a2 and Slc22a3 is maintained by the replacement promoter and also in the absence of transcriptional overlap with Air. These results exclude a role for the Igf2r promoter and for transcriptional overlap between Igf2r and Air in silencing Air, Slc22a2 and Slc22a3. Although these results do not completely exclude a role for a double‐stranded RNA silencing mechanism, they do allow the possibility that the Air RNA has intrinsic cis silencing properties.
TEXTURE ANALYSIS OF FACES OF TWINS BY USING IMAGE PROCESSING TECHNIQUES

Texture Analysis has been an active area of research over the past twenty five years. Today, texture analysis plays an important role in many tasks ranging from remote sensing to bio-medical image analysis. Textures, the repeated patterns, have different frequency components along different orientations. Texture analysis is important in many applications like image database retrieval, industrial, agricultural and bio- medical applications. Texture analysis and classification are based on three different approaches; statistical, spectral and structural. We have proposed statistical approaches for analyzing the faces of twins and the components on the faces.