Miracle-dz/UniFAR-FTUs huggingface dataset:
Growth factors and psychiatric disorders

Symposium on Growth factors and psychiatric disorders, held at the Novartis Foundation, London, 20-22 March 2007. Editors: Derek J. Chadwick (Organizer) and Jamie Goode. This symposium is based on a proposal made by Moses Chao. Moses Chao Chair's introduction. Daniel C. Javitt Phenomenology, aetiology and treatment of schizophrenia. Discussion. Jonathan Flint, Sagiv Shifman, Marcus Munafo and Richard Mott Genetic variants in major depression. Discussion. Eero Castren and Tomi Rantamaki Neurotrophins in depression and antidepressant effects. Discussion. Jinbo Fan and Pamela Sklar Genetics of bipolar disorder: focus on BDNF Val66Met polymorphism. Discussion. David A. Talmage Mechanisms of neuregulin action. Discussion. General discussion I. H. Akil, S. J. Evans, C. A. Turner, J. Perez, R. M. Myers, W. E. Bunney, E. G. Jones, S. J. Watson and other members of the Pritzker Consortium The fibroblast growth factor family and mood disorders. Discussion. Jay N. Giedd, Rhoshel K. Lenroot, Philip Shaw, Francois Lalonde, Mark Celano, Samantha White, Julia Tossell, Anjene Addington and Nitin Gogtay Trajectories of anatomic brain development as a phenotype. Discussion. Bai Lu and Keri Martinowich Cell biology of BDNF and its relevance to schizophrenia. Discussion. Enrico Tongiorgi and Gabriele Baj Functions and mechanisms of BDNF mRNA trafficking. Discussion. Amar Sahay and Rene Hen Hippocampal neurogenesis and depression. Discussion. Andres Buonanno, Oh-Bin Kwon, Leqin Yan, Carmen Gonzalez, Marines Longart, Dax Hoffman and Detlef Vullhorst Neuregulins and neuronal plasticity: possible relevance in schizophrenia. Discussion. Zhe-Yu Chen, Kevin Bath, Bruce McEwen, Barbara Hempstead and Francis Lee Impact of genetic variant BDNF (Val66Met) on brain structure and function. Discussion. General discussion II. D. Malaspina, M. Perrin, K. R. Kleinhaus, M. Opler and S. Harlap Growth and schizophrenia: aetiology, epidemiology and epigenetics. Discussion. Luiz M. Camargo, Qi Wang and Nicholas J. Brandon What can we learn from the disrupted in schizophrenia 1 interactome: lessons for target identification and disease biology? Discussion. Michael Spedding and Pierre Gressens Neurotrophins and cytokines in neuronal plasticity. Discussion. Moses Chao Closing remarks. Index of contributors. Subject index.
Trust and Reliance Based on System Accuracy

Trust plays an important role in various user-facing systems and applications. It is particularly important in the context of decision support systems, where the system's output serves as one of the inputs for the users' decision making processes. In this work, we study the dynamics of explicit and implicit user trust in a simulated automated quality monitoring system, as a function of the system accuracy. We establish that users correctly perceive the accuracy of the system and adjust their trust accordingly.
Multi-objective Parametric Control of Blood Glucose Concentration for Type 1 Diabetes

The main objective of automatic blood glucose concentration controllers is to avoid hypo- and hyper-glycemia, i.e. maintain the concentration levels between 60 and 120 mg/dL, by optimally manipulating the insulin infusion rates. In the medical literature, hypoglycemia is considered to be more harmful to an individual's health than hyperglycemia. In this work, a multiobjective controller that can take into account this asymmetry in the objective function and can be implemented with minimal computational effort, by using parametric programming techniques, is proposed. An alternative technique that gives higher priority to the satisfaction of constraints on hypoglycemia than on hyperglycemia is also presented. The performance of both the controllers is analyzed under meal disturbances.
Two methods for voxel detail enhancement

In this paper I describe a novel technique called voxel detail enhancement that, inspired by pixel art scaling algorithms for 2D images, produces finely detailed (3D) voxel maps from the coarser maps that would be edited by a player's actions during gameplay. I describe two methods which deterministically generate fine voxel fragments that depend only on the occupancy of a local window of coarse voxels. Enhanced voxel maps can provide attractive visuals for voxel-based games without requiring the player to manipulate the world at a finer scale. Decoupling the geometry used in graphics and physics from the construction and destruction mechanics of the game opens up new gameplay possibilities in the design space occupied by games like Minecraft and Voxelstein 3D.
Factors Affecting IUCD Discontinuation in Nepal

Information related to contraception discontinuation, especially in the context of Nepal is very limited. A nested case-control study was carried out to determine the factors affecting discontinuation of intrauterine contraceptive devices (IUCDs). A total of 115 cases (IUCD discontinuers) and 115 controls (IUCD continuers) were randomly selected based on the data obtained from the user’s record of a family planning center in Kathmandu. Matching criteria were age during insertion and date of insertion of IUCD. Logistic regression was used to analyze the data. When cases were compared with controls, the results showed that place of residence, sex of last child, reproductive intention, experience of side effects, and follow-up practice were associated with discontinuation of the IUCD. Experience of side effects has been seen as the major reason for discontinuation. The results suggest that side effects after IUCD insertion should be properly discussed and promptly treated to reduce the discontinuation rate.
Dark Current Characterization in CCD's

To investigate the nature of dark current in CCD's many test structures have been made. All of them have the disadvantage that they do not represent the sensor close enough to extract the relevant dark current parameters. To avoid this the sensor itself has been used as a test structure. DC measurements of dark current versus gate voltage have been taken. With an additional conductive glue layer on the image section we have determined the influence of the window in the polysilicon gates with respect to the dark current. By pulsing the gates the bulk and interface contribution has been found.
Robotic vehicles to simulate RFID-based vehicular ad hoc networks

The study of vehicular ad hoc networks (VANETs) is usually performed by means of software simulations. However, in order to evaluate the integration of Radio Frequency Identification (RFID) technology into VANETs functionality, we have developed a scale test bench. It is composed of several vehicles provided with an RFID reader to detect the tags on the road, and the wireless native capability of the VANETs to communicate with other vehicles. The main objective of this RFID-VANET simulator is to show the interoperation of these technologies as a previous step to real implementations in vehicles. For this reason, we have incorporated specific circuitry to the small robots, and programmed them to reproduce real scenarios.
PeerCDN: A novel P2P network assisted streaming content delivery network scheme

Providing scalable streaming media service over the internet is a demanding task nowadays, CDN(Content Delivery Network) and P2P are the main approaches while both have pros and cons. We propose a novel hybrid architecture - PeerCDN to combine the two approaches seamlessly with their inherited excellent features. PeerCDN is a two-layer streaming architecture. Upper layer is a server layer which is composed of original CDN servers including origin servers and replica servers. Lower layer consists of groups of clients who request the streaming services, each client is considered as a client peer in the group. Each group of client peers is led by the nearby replica server. Client peers contribute their resource through the coordination of the leader peer. The scheme uses a revised Kademlia-like protocol for peer-to-peer topology management and DHT for data retrieval. It constructs a topology-aware overlay network and results reduced jitter. PeerCDN makes best use of original investment and infrastructure. The service capacity is larger than traditional CDN system with the participation of the client peers. Also, the topology-aware overlay network restricts the unnecessary backbone bandwidth consuming during client peer sharing. The experiment result shows that PeerCDN has better features than the CDN and pure p2p approaches.
Genetic variation in the presynaptic norepinephrine transporter is associated with blood pressure responses to exercise in healthy humans

Background The presynaptic norepinephrine transporter (NET) mediates synaptic clearance and recycling of norepinephrine. NET-deficient transgenic mice have elevated blood pressure (BP), heart rate, and catecholamine concentrations. However, the in-vivo effects of common NET variants on cardiovascular regulation at rest and during exercise are unknown. Methods We studied cardiovascular responses and plasma catecholamine concentrations at rest and during bicycle exercise at increasing workloads (25, 50, and 75 W) in 145 healthy participants. We used multiple linear regressions to analyze the effect of common, purportedly functional polymorphisms in NET (rs2242446 and rs28386840) on cardiovascular measures. Results 44 and 58.9% of participants carried at least one variant allele for NET T-182C and A-3081T, respectively. Systolic BP during exercise and systolic BP-area under the curve were higher in carriers of variant NET alleles (P=0.003 and 0.009 for T-182C and A-3081T, respectively) and NET haplotype -182C/-3081T compared with -182T/-3081A (all P<0.01). Diastolic BP during exercise was also higher at lower, but not at higher exercise stages in carriers of NET -182C (P<0.01) and -3081T variants (P<0.05). NET genotypes were not associated with catecholamine concentrations or heart rate. Conclusion Common genetic NET variants (-182C and -3081T) are associated with greater BP response to exercise in humans.
Potential–density pairs for spherical galaxies and bulges: the influence of scalar fields

A family of potential-density pairs has been found for spherical haloes and bulges of galaxies in the Newtonian limit of scalar-tensor theories of gravity. The scalar field is described by a Klein-Gordon equation with a source that is coupled to the standard Poisson equation of Newtonian gravity. The net gravitational force is given by two contributions: the standard Newtonian potential plus a term stemming from massive scalar fields. General solutions have been found for spherical systems. In particular, we compute potential-density pairs of spherical, galactic systems, and some other astrophysical quantities that are relevant to generate initial conditions for spherical galaxy simulations.
Two Algorithms of Power Loading for MCM System in Nakagami Fading Channel

We consider two non-iterative algorithms of adaptive power loading for multicarrier modulation (MCM) system, The first one minimizes the average power of the system transmitter and ensures the preset average bit-error rate, while the second reduces the average transmitting power subject to the given values of demanded bit-error rate and of the outage probability. The algorithms may be used for power-efficient management of the up-link in cellular communication, where mobile terminals use rechargeable batteries, or of the downlink in satellite communication with solar power source of a transponder. We present performance analysis of the adaptive MCM systems supported by computer simulation for the case of the m-Nakagami fading and additive white Gaussian noise in the forward and backward channels. Evaluation of the power gain of the proposed strategies and its comparison with uniform power loading shows that the gain depends on the fading depth and average signal to noise ratio in the system sub-channels.
Comparison of multilayer and radial basis function neural networks for text-dependent speaker recognition

This paper compares the use of multilayer perceptrons (MLPs) trained on backpropagation and radial basis function (RBF) neural networks for the task of text-dependent speaker recognition. 10 classifier networks were generated for each of 20 male-speakers using randomly-generated training sets consisting of 6 true speaker utterances and 19 false speaker utterances (one from each of the false speakers). The resulting networks were then used to assess verification and identification performance for each of the network architectures. The results clearly indicate that the choice of true and false speaker utterances used in the training set has a crucial effect on the success of the classifier. The overall superiority of performance reported in general for RBF networks over MLPs would appear to be due to the reduced sensitivity of the former to a poor training set when compared to the performance of an MLP for the same training set. When both networks are presented with their "best" training sets, however, the RBF network still significantly out-performs the MCP.
Difficulties in detecting hybridization.

This is an electronic version of an article published in Systematic Biology [Holder, Mark T. , Jennifer A. Anderson, and Alisha K. Holloway. Difficulties in detecting hybridization. Systematic Biology, 50(6):978{982, 2001. ] Systematic Biology is available online at informaworld http://dx.doi. org/10.1080/106351501753462911
Lexicographical order Max-Min fair source quota allocation in mobile Delay-Tolerant Networks

There is a big potential to enable more efficient data dissemination in mobile Delay-Tolerant Networks (DTNs) with the concurrent use of multi-copy forwarding and social metrics. However, this also leads to the possibility of severely overloading the relay nodes with high social metrics, and consequent performance degradation. We propose a fair source quota allocation algorithm to effectively alleviate the load while ensuring their dissemination fairness, i.e, Lexicographical order Max-Min Fairness(LMMF). In this paper, A fair source quota allocation algorithm along with an implementation scheme was presented to take advantage of the features of social networks and social forwarding for higher delivery performance. Extensive simulations based on trace data demonstrate that our mechanism greatly reduces the delivery-ratio degradation caused by uneven load while ensuring fairness among the network users.
VIDEOS WITH SCENES RECOVERY USING RAIN PIXEL ALGORITHM

Rain removal is a extremely useful and very important technique in many applications such as surveillance and movie editing. Recently, several rain removal algorithms have been proposed, where photometric, chromatic, and probabilistic properties of the rain pixels have been utilized to discover and remove the rainy effect. The existing methods generally work well with relatively static and light rain scenes, but in the existing methods the number of steps and the time required for the development of system are more and accuracy gives poor results as compared to proposed system. Proposed algorithm has better approach in rain removal process compared with existing System in above three parameters. Extensive simulation results show that the proposed algorithm shows a much better performance for rainy scenes than the existing algorithms. Rain produces exact intensity variation in images and videos, which degrade the performance of outdoor vision systems. These intensity variations rely on various factors, such as the camera parameters, the properties of rain, and the brightness of the scene. Removal of rain streaks is one of the challenging problem in video, due to the random spatial distribution and fast motion of rain. Rain removal has found various applications in the field of security surveillance, video/movie editing, video indexing/retrieval and vision based navigation. This paper provides various techniques or methods that are used to remove the rainy effect.
Erectile dysfunction, masculinity, and psychosocial outcomes: a review of the experiences of men after prostate cancer treatment

Prostate cancer (PC) treatment side-effects such as erectile dysfunction (ED) can impact men’s quality of life (QoL), psychosocial and psycho-sexual adjustment. Masculinity (i.e., men’s identity or sense of themselves as being a man) may also be linked to how men respond to PC treatment and ED however the exact nature of this link is unclear. This review aims to provide a snapshot of the current state of evidence regarding ED, masculinity and psychosocial impacts after PC treatment. Three databases (Medline/PsycINFO, CINHAL, and EMBASE) were searched January 1st 1980 to January 31st 2016. Study inclusion criteria were: patients treated for PC; ED or sexual function measured; masculinity measured in quantitative studies or emerged as a theme in qualitative studies; included psychosocial or QoL outcome(s); published in English language, peer-reviewed journal articles. Fifty two articles (14 quantitative, 38 qualitative) met review criteria. Studies were predominantly cross-sectional, North American, samples of heterosexual men, with localised PC, and treated with radical prostatectomy. Results show that masculinity framed men’s responses to, and was harmed by their experience with, ED after PC treatment. In qualitative studies, men with ED consistently reported lost (no longer a man) or diminished (less of a man) masculinity, and this was linked to depression, embarrassment, decreased self-worth, and fear of being stigmatised. The correlation between ED and masculinity was similarly supported in quantitative studies. In two studies, masculinity was also a moderator of poorer QoL and mental health outcomes for PC patients with ED. In qualitative studies, masculinity underpinned how men interpreted and adjusted to their experience. Men used traditional (hegemonic) coping responses including emotional restraint, stoicism, acceptance, optimism, and humour or rationalised their experience relative to their age (ED inevitable), prolonged life (ED small price to pay), definition of sex (more than erection and penetration), other evidence of virility (already had children) or sexual prowess (sown a lot of wild oats). Limitations of studies reviewed included: poorly developed theoretical and context-specific measurement approaches; few quantitative empirical or prospective studies; moderating or mediating factors rarely assessed; heterogeneity (demographics, sexual orientation, treatment type) rarely considered. Clinicians and health practitioners can help PC patients with ED to broaden their perceptions of sexual relationships and assist them to make meaning out of their experience in ways that decrease the threat to their masculinity. The challenge going forward is to better unpack the relationship between ED and masculinity for PC patients by addressing the methodological limitations outlined so that interventions for ED that incorporate masculinity in a holistic way can be developed.
pH Regulation in the Intracellular Malaria Parasite, Plasmodium falciparum

The mechanism by which the intra-erythrocytic form of the human malaria parasite, Plasmodium falciparum, extrudes H+ ions and thereby regulates its cytosolic pH (pH i ), was investigated using saponin-permeabilized parasitized erythrocytes. The parasite was able both to maintain its resting pH i and to recover from an imposed intracellular acidification in the absence of extracellular Na+, thus ruling out the involvement of a Na+/H+ exchanger in both processes. Both phenomena were ATP-dependent. Amiloride and the related compound ethylisopropylamiloride caused a substantial reduction in the resting pH i of the parasite, whereas EMD 96785, a potent and allegedly selective inhibitor of Na+/H+ exchange, had relatively little effect. The resting pH i of the parasite was also reduced by the sulfhydryl reagent N-ethylmaleimide, by the carboxyl group blockerN,N′-dicyclohexylcarbodiimide, and by bafilomycin A1, a potent inhibitor of V-type H+-ATPases. Bafilomycin A1 blocked pH i recovery in parasites subjected to an intracellular acidification and reduced the rate of acidification of a weakly buffered solution by parasites under resting conditions. The data are consistent with the hypothesis that the malaria parasite, like other parasitic protozoa, has in its plasma membrane a V-type H+-ATPase, which serves as the major route for the efflux of H+ ions.
Including User Strategies in the Evaluation of Graphic Design Interfaces for Browsing Documents

This article presents an analytical evaluation method for innovative and graphically rich displays beyond the common WIMP interfaces. This method is based on user strategies and compares different algorithms for creating 2D or 3D environments and leads to a correlation measure which can be consulted in the creation process of such environments. The results suggest, that the graphical algorithm may have more influence on the quality of maps than user strategies. Therefore, the correct choice of appropriate arithmetic algorithms is crucial. Furthermore, the article discusses the extension of the evaluation method to 3D environments for semantic organization of homogeneous objects. By presenting this method and its results, an example is given for rigid and user-oriented evaluation of advanced graphical interfaces which are applied in the internet.
Interacción humano computadora para personas con capacidad motriz disminuida mediante un dispositivo wiimote

En nuestra era moderna, las computadoras son la base fundamental para poder estar conectados con el resto del mundo. Este derecho no se le debe privar a nadie, ni siquiera a aquellas personas con capacidades motrices disminuidas. En los últimos años, interfaces de todo tipo han sido desarrolladas en el área de la Interacción Humano Computadora para ayudarles a acceder a una computadora de la forma más segura y eficiente posible. En este artículo se presenta una interface cómoda y sobre todo económica para que personas con capacidad motriz disminuida en sus brazos y manos puedan controlar satisfactoriamente el mouse del ordenador, abriéndoles paso a un mundo infinito de posibilidades. Palabras Clave: Head Tracking, Interacción Humano Computadora, Wiimote, Discapacidad Motriz.
Software defined networking for heterogeneous access networks

5G is currently being investigated and defined while Time-Wavelength Division Multiplexed Passive Optical Networks (TWDM-PONs) and Digital Broadcasting Systems (DBS) are respectively standardised and deployed. Software Defined Networking (SDN) can provide reconfigurability, the stringent latency requirements, adaptive network functionality, and the Quality of Experience (QoE) that a heterogeneous next generation access network ecosystem needs. These new network requirements are imposed by the continuous growth of the internet, the explosion of smart devices and the increasing attempts to consolidate Mobile Fronthauling (MFH) with emerging IP based video streaming applications. This paper deliberates on the technical challenges related to the deployment of SDN for heterogeneous access and how an SDN enabled orchestration layer can absorb the rapidly increasing demand for high quality IP based service delivery. In particular the concepts of network function decentralisation, ubiquitous support for MFH using CPRI and CPRI over Ethernet (CPRIoE) services, OLT-side intelligent caching using local NFV, QoE assurance via CDN ISP collaboration, and local video streaming replacement services by using OLT-side SatIP servers are presented.