Miracle-dz/UniFAR-FTUs huggingface dataset:
The Scholarship of Teaching and Learning: Help for Academic Tour Guides.

The presence of scholarship of teaching and learning (SoTL), or its absence, has greatly impacted my undergraduate studies. While professors are experts in their subject matter, they do not always know how to reach students. SoTL provides resources to address such disconnects. Just-in-time teaching (JiTT) is one example of a SoTL-informed teaching assignment that can help students learn more effectively. Because SoTL helps professors understand how students learn, it can encourage excellence in the classroom.
Relative Value of Normalized Sonographic In Vitro Analysis of Arteriosclerotic Plaques of Internal Carotid Artery

Background and Purpose— A close correlation between B-mode sonography and the histopathology and surface structure of plaque is rarely seen in vivo with high-grade stenoses of the extracranial carotid artery. The goal of this study was to determine whether normalized gray scale analysis and surface analysis of the plaque are capable of characterizing the attributes correctly. Methods— Optimized B-mode images of 107 carotid endarterectomy specimens were captured, and the gray scale median (GSM) was calculated. The specimens were classified histologically into 3 groups: (1) calcium-rich hard plaques, (2) lipid-rich soft plaques, and (3) combined plaques. The surfaces of the plaques were classified as smooth or rough on the basis of standardized reference samples. The endoluminal surface was digitally documented in vitro by videoendoscopy and again classified into the same categories. All stages of the investigation were performed by 2 observers at 2 different times. Results— Evaluation of the GSM showed close interobserver and intraobserver correlation (P <0.01, R >0.8). However, there was only 46% agreement between the GSM and the histopathological findings. In both in vitro angioscopy (&kgr;=0.936, P <0.001) and sonographic evaluation (&kgr;=0.842, P <0.001), there was a high correlation between the observers with regard to the evaluable specimens. In 73%, agreement was observed between the sonographic image and angioscopy. Conclusions— Normalized gray scale analysis and evaluation of the plaque surface in an in vitro study make possible observer-independent evaluation. The composition of the plaque cannot be visualized with sufficient accuracy by sonographic GSM analysis. This also applies to the correlation between sonography and actual surface composition of the plaque.
Präferenz für Intuition und Deliberation (PID)

Zusammenfassung: Personen unterscheiden sich darin, ob sie bevorzugt intuitiv oder reflektiv entscheiden (Epstein et al., 1996). Um diese individuellen Unterschiede zu erfassen, wurde ein neues Fragebogenmas konstruiert, das auf zwei unabhangigen Skalen die Praferenz fur Intuition bzw. die Praferenz fur Deliberation misst. Intuition wird hier, anders als bei Epstein, nicht als heuristisch-affektiver Modus verstanden, sondern als ein rein affektiver Modus. Deliberation ist konzipiert als reflektiver, kognitionsbasierter Modus. In drei Studien wird die Konstruktion, Uberprufung der Zweidimensionalitat und Validierung der Skala anhand von insgesamt uber 2500 Versuchspersonen berichtet. In einer konfirmatorischen Faktorenanalyse werden Fitindizes von GFI = . 88, RMSEA = . 09 erreicht. Praferenz fur Intuition korreliert positiv mit schnellem Entscheiden, Extraversion und Vertraglichkeit und ist unabhangig von der Fahigkeit zu logischem Denken. Praferenz fur Deliberation korreliert mit Gewissenhaftigkeit, Perfekt.
Shaping the story: rhetoric, persuasion and creative writing in organisational ethnography

Every writer is engaged in processes of persuasion, not only in their communicating with the reader but in the very processes of thinking out their ideas. Rhetoric is inevitably an integral part of research work and research writing. All social science writing involves the creation of an artful product. This proposition is examined with reference to the author's own writing about his ethnographic research on management and key parallels are observed between the techniques of creating an ethnographic account and the rhetorical style of the creative fiction writer. The basic issues of the paper are raised in the story of a dialogue between the researcher and Tom Beeston.
Language curriculum development research at university level

This article provides an account of an example of curriculum development over a 10-year period. Motivated by a belief in the value of comprehensible input, the purposeful teaching of language in a context and the need for a variety of text types linked to the development of interpersonal skills, the authors have devised a model for task-based curriculum design and, together with many of their colleagues, have implemented and evaluated it on two occasions. The use of diaries and questionnaires on the first occasion enabled a number of lessons to be learned and these helped considerably in creating a second application where the testimony of the student population through a detailed questionnaire shows the success of the operation.
Balancing Caregiving and Work

Positing role conflict as a bidirectional construct in which work interferes with caregiving (WIC) and caregiving interferes with work (CIW), this study investigated its antecedents (demands and support of caregiving and work) and consequences (role strain). A national sample of 583 women between the ages of 50 and 64 years identified using random-digit-dial procedures completed a telephone survey. Structural equation modeling revealed that caregiving demands were positively associated with CIW and caregiving burden; instrumental caregiving support reduced CIW and caregiving burden. Work demands were positively associated with WIC, CIW, caregiving burden, and work burden. Emotional workplace support reduced WIC, CIW, and work burden. CIW and WIC were positively associated with caregiving burden; only WIC was positively associated with work burden. Findings suggest that demands and supports related to the caregiving role do not influence work-related role strain; work demands and supports influence role strain experienced from both caregiving and work domains.
Brai nD AD 2Receptor sPredict Reinforcin gEffect so fStimulant sin Humans :Replicatio nStudy

KE YWORDS raclopride ;addiction ;vulnerability ;PET ;methylphenidate ;reinforce- ment ;striatum ABSTRACT W eha dshow ntha tstriata lD AD 2receptor slevel spredicte dth erein- forcin gresponse st oth epsychostimulan tdru gmethylphenidat ei nnondrug-abusing subjects . Here ,w eassesse dth ereplicabilit yo fthi sfinding . W emeasure dD 2receptors wit hPE Tan d( 11 C)racloprid e(twic et odetermin estability )i nseve nnondrug-abusing subject st oasses si fthe ypredicte dth eself-report so f"drug-liking "t ointravenous methylphenidat e(0. 5mg/kg) . D AD 2measure swer esignificantl ycorrelate dwit h"drug- liking "i nbot hevaluation s( r 50.8 2an d r 50.78) ;subject swit hth elowes tlevels reporte dth ehighe rrating so f"drug-liking "an dvic eversa . Thes eresult sreplicat eour previou sfinding san dprovid efurthe revidenc etha tstriata lD AD 2receptor smodulate reinforcin gresponse st ostimulant si nhuman san dma yunderli epredispositio nfo rdrug self-administration . Synaps e46:7 9- 82 ,2002. ©200 2Wiley-Liss ,Inc.
The Scheduling of Flexible Manufacturing System Based on RBF Neural Network

Improving the procedure management for flexible manufacturing system (FMS) is still one of the main topics in present industries. In this paper, a radial basis function neural network (RBF-NN) model is proposed to schedule jobs in a general FMS. First, a FMS and the problem are described. Then, a RBF-NN is presented; the iterative training algorithm employs the gradient algorithm to minimize a function that measures the difference between the network output and the desired one. Finally, according to some scheduling rules the ideal configuration of the RBF-NN that is used for the criterion of mean tardiness is figured out. The ideal configuration of the RBF-NN has 8 input nodes, 17 nodes in the hidden layer, and 13 nodes in the output layer. Simulation results show that the combinations are the optimal strategies.
Comparing Stress ECG Enhancement Algorithms With an introduction to a filter bank based approach

here are two predominant types of noise T that contaminate the electrocardiogram (ECG) acquired during a stress test: the baseline wander noise (BW) and electrode motion artifact, and electromyogram-induced noise (EMG) [ 11. BW noise is at a lower frequency, caused by respiration and motion of the subject or the leads. The frequency components of BW noise are usually below 0.5 Hz, and extend into the frequency range of the ST segment during a stress test. EMG noise, on the other hand, is predominantly at higher frequencies, caused by increased muscle activity and by mechanical forces acting on the electrodes. The frequency spectrum of the EMG noise overlaps that of the ECG signal and extends even higher in the frequency domain. In this article, we review some of the published ECG enhancing techniques to overcome the noise problems, and compare their performance on stress ECG signals under adverse noise scenarios. We also describe the Filter Bank (FB) based ECG enhancing algorithm [9].
Trial of short-course antimicrobial therapy for intraabdominal infection.

BACKGROUND The successful treatment of intraabdominal infection requires a combination of anatomical source control and antibiotics. The appropriate duration of antimicrobial therapy remains unclear. METHODS We randomly assigned 518 patients with complicated intraabdominal infection and adequate source control to receive antibiotics until 2 days after the resolution of fever, leukocytosis, and ileus, with a maximum of 10 days of therapy (control group), or to receive a fixed course of antibiotics (experimental group) for 4±1 calendar days. The primary outcome was a composite of surgical-site infection, recurrent intraabdominal infection, or death within 30 days after the index source-control procedure, according to treatment group. Secondary outcomes included the duration of therapy and rates of subsequent infections. RESULTS Surgical-site infection, recurrent intraabdominal infection, or death occurred in 56 of 257 patients in the experimental group (21.8%), as compared with 58 of 260 patients in the control group (22.3%) (absolute difference, -0.5 percentage point; 95% confidence interval [CI], -7.0 to 8.0; P=0.92). The median duration of antibiotic therapy was 4.0 days (interquartile range, 4.0 to 5.0) in the experimental group, as compared with 8.0 days (interquartile range, 5.0 to 10.0) in the control group (absolute difference, -4.0 days; 95% CI, -4.7 to -3.3; P<0.001). No significant between-group differences were found in the individual rates of the components of the primary outcome or in other secondary outcomes. CONCLUSIONS In patients with intraabdominal infections who had undergone an adequate source-control procedure, the outcomes after fixed-duration antibiotic therapy (approximately 4 days) were similar to those after a longer course of antibiotics (approximately 8 days) that extended until after the resolution of physiological abnormalities. (Funded by the National Institutes of Health; STOP-IT ClinicalTrials.gov number, NCT00657566.).
Comparison of ground reaction force during different angle of squatting

Dali, S. , Justine, M. , Ahmad, H. & Othman, Z. (2013). Comparison of ground reaction force during different angle of squatting. J. Hum. Sport Exerc. , 8(3), pp.778-787. Squatting is a form of closed kinetic chain movement which commonly being employed in exercise training. However, little is known regarding the amount of force being imposed on the knee at different angles of squat. Thus, the purpose of this study was to compare the vertical ground reaction force (VGRF) at different angles of squatting among the military personnel. Thirty-seven subjects (age=27.1±2.77 years old) participated in this cross-sectional comparative study. The peak of VGRF was identified during squatting at 40o, 70o, and 110 o of knee flexion, which was measured using a force platform. The data were analysed using the one way repeated measure ANOVA and Pairwise Comparisons via Bonferroni adjustment. The VGRF were shown significantly different between the three angles of squatting (p 0 .05), the result was corrected using Greenhouse-Geiser Epsilon and continued to show a significant different [F (1.36, 49.08)=43.56] (p<0.05). The effect size was large (ηρ²=0.55). This study suggests that the angle of knee flexion during squatting exercise may influence VGRF. Deep squatting was found to generate the highest VGRF compared to semi and half squatting. Thus, it is suggested that squatting may be best performed at smaller angle in order to avoid excessive force that may be detrimental
GIRK Channel Activation Via Adenosine or Muscarinic Receptors Has Similar Effects on Rat Atrial Electrophysiology

Abstract: G protein–coupled inwardly rectifying K+ channels (GIRK) are important in the regulation of heart rate and atrial electrophysiology. GIRK channels are activated by G protein–coupled receptors, including muscarinic M2 receptors and adenosine A1 receptors. The aim of this study was to characterize and compare the electrophysiological effects of acetylcholine (ACh) and adenosine on GIRK channels in rat atria. Action potential duration at 90% repolarization (APD90), effective refractory period (ERP), and resting membrane potential (RMP) were investigated in isolated rat atria by intracellular recordings. Both the adenosine analog N6-cyclopentyladenosine (CPA) and ACh profoundly shortened APD90 and ERP and hyperpolarized the RMP. No additive or synergistic effect of CPA and ACh coapplication was observed. To antagonize GIRK channel activation, the specific inhibitor rTertiapin Q (TTQ) was applied. The coapplication of TTQ reversed the CPA and ACh-induced effects. When TTQ was applied without exogenous receptor activator, both APD90 and ERP were prolonged and RMP was depolarized, confirming a basal activity of the GIRK current. The results reveal that activation of A1 and M2 receptors has a profound and equal effect on the electrophysiology in rat atrium. This effect is to a major extent mediated through GIRK channels. Furthermore, these results support the notion that atrial GIRK currents from healthy hearts have a basal component and additional activation can be mediated via at least 2 different receptor mechanisms.
The Anthropology of Life After AIDS: Epistemological Continuities in the Age of Antiretroviral Treatment

Anthropologists working on HIV are increasingly reframing their research as taking place in “the age of treatment,” marking a shift from “the age of AIDS. ” The age of treatment is characterized by the increasing biomedicalization of HIV, which has come about as a result of improved pharmaceutical and surveillance technologies and the presumption by international experts in global health that HIV could be eradicated in the near future through biomedical interventions. Despite this radical transformation, I argue that there are many important epistemological continuities for anthropologists researching HIV/AIDS in the twenty-first century. This review identifies such continuities between anthropological research conducted prior to and that conducted since the availability of life-saving treatment for HIV.
Acidic nuclear phosphoprotein 32kDa (ANP32)B-deficient mouse reveals a hierarchy of ANP32 importance in mammalian development

The highly conserved ANP32 proteins are proposed to function in a broad array of physiological activities through molecular mechanisms as diverse as phosphatase inhibition, chromatin regulation, caspase activation, and intracellular transport. On the basis of previous analyses of mice bearing targeted mutations of Anp32a or Anp32e, there has been speculation that all ANP32 proteins play redundant roles and are dispensable for normal development. However, more recent work has suggested that ANP32B may in fact have functions that are not shared by other ANP32 family members. Here we report that ANP32B expression is associated with a poor prognosis in human breast cancer, consistent with the increased levels of Anp32b mRNA present in proliferating wild-type (WT) murine embryonic fibroblasts and stimulated WT B and T lymphocytes. Moreover, we show that, contrary to previous assumptions, Anp32b is very important for murine embryogenesis. In a mixed genetic background, ANP32B-deficient mice displayed a partially penetrant perinatal lethality that became fully penetrant in a pure C57BL/6 background. Surviving ANP32B-deficient mice showed reduced viability due to variable defects in various organ systems. Study of compound mutants lacking ANP32A, ANP32B, and/or ANP32E revealed previously hidden roles for ANP32A in mouse development that became apparent only in the complete absence of ANP32B. Our data demonstrate a hierarchy of importance for the mammalian Anp32 genes, with Anp32b being the most critical for normal development.
Hot and Cold Housing Markets: International Evidence

This paper examines the experience of 14 developed countries for which there are about 30 years of quarterly inflation-adjusted housing price data. Price dynamics is modelled as a combination of a country-specific component and a cyclical component. The cyclical component is a two-state Markov switching process with parameters common to all countries. We find that the latent cyclical variable captures previously undocumented changes in the volatility of real housing price increases. These volatility phases are quite persistent (about six years, on average) and occur with about the same unconditional frequency over time. In line with previous studies, the mean of real housing price increases can be predicted to be larger when lagged values of those increases are large, real GDP growth is high, unemployment falls, and interest rates are low or have declined. Our findings have important implications for risk management in regard to residential property markets.
A new QoS provisioning method for adaptive multimedia in cellular wireless networks

Third generation cellular wireless networks are designed to support adaptive multimedia by controlling individual ongoing flows to increase or decrease their bandwidth in response to changes in traffic load There is growing interest in quality of service (QoS) provisioning under this adaptive multimedia framework, in which a bandwidth adaptation algorithm needs to be used in conjunction with the call admission control algorithm. This paper presents a novel method for QoS provisioning via the use of the average reward reinforcement learning, which can maximize the network revenue subject to several predetermined QoS constraints. By considering handoff dropping probability, average allocated bandwidth and intraclass fairness simultaneously, our algorithm formulation guarantees that these QoS parameters are kept within predetermined constraints. Unlike other model-based algorithms, our scheme does not require explicit state transition probabilities and therefore the assumptions behind the underlying system model are more realistic than those in previous schemes. Moreover, by considering the status of neighboring cells, the proposed scheme can dynamically adapt to changes in traffic condition. Simulation results demonstrate the effectiveness of the proposed approach in adaptive multimedia cellular networks
Drop-Out from Adult Education: Social Environment, School Culture and Perceptions.

This article concerns drop‐out from daytime education for adults. Special attention is paid to gender differences. According to the theoretical framework developed by Tinto, the level of integration in the academic system and the social system of the institute is an important determining factor in drop‐out. Research carried out by, for example, Woodley and Parlett and Bean and Metzner emphasizes the importance of two social systems in drop‐out: the institute and the student's own social environment. School drop‐out was first approached from this point of view in the research reported in this article. The results showed that the place of the school qua centrality in the social environment was virtually the same for both school drop‐outs and students. Second, it is argued that in research on school drop‐out insufficient attention is paid to ‘perceptions’. The research therefore also places school drop‐out in the context of the way teachers and students perceive the social and cognitive functioning of the la.
Immunocytochemical observations on macrophage populations in normal fetal and adult human liver

Phenotypic expression of macrophages was studied immunocytochemically in 25 human fetal livers at various stages of development and in 20 normal human adult livers. A panel of commercially available polyclonal and monoclonal antibodies (KP1, Mac387, LN3, CR3/43, and antibodies against muramidase, alpha‐1‐antitrypsin, and factor XIIIa) was applied to paraffin sections. From the seventh week of gestation macrophages in the fetal liver showed differences in distribution with the various antibodies. Macrophages in adult liver similarly varied in morphology and phenotypic expression. In the light of these results, we conclude that the population of human liver macrophages is heterogeneous from an early stage of fetal development and that this heterogeneity extends into adult life.
Exome sequencing identifies a novel EP300 frame shift mutation in a patient with features that overlap cornelia de lange syndrome

Rubinstein–Taybi syndrome (RTS) and Cornelia de Lange syndrome (CdLS) are genetically heterogeneous multiple anomalies syndromes, each having a distinctive facial gestalt. Two genes (CREBBP and EP300) are known to cause RTS, and five (NIPBL, SMC1A, SMC3, RAD21, and HDAC8) have been associated with CdLS. A diagnosis of RTS or CdLS is molecularly confirmed in only 65% of clinically identified cases, suggesting that additional causative genes exist for both conditions. In addition, although EP300 and CREBBP encode homologous proteins and perform similar functions, only eight EP300 positive RTS patients have been reported, suggesting that patients with EP300 mutations might be escaping clinical recognition. We report on a child with multiple congenital abnormalities and intellectual disability whose facial features and complex phenotype resemble CdLS. However, no mutations in CdLS‐related genes were identified. Rather, a novel EP300 mutation was found on whole exome sequencing. Possible links between EP300 and genes causing CdLS are evident in the literature. Both EP300 and HDAC8 are involved in the regulation of TP53 transcriptional activity. In addition, p300 and other chromatin associated proteins, including NIPBL, SMCA1, and SMC3, have been found at enhancer regions in different cell types. It is therefore possible that EP300 and CdLS‐related genes are involved in additional shared pathways, producing overlapping phenotypes. As whole exome sequencing becomes more widely utilized, the diverse phenotypes associated with EP300 mutations should be better understood. In the meantime, testing for EP300 mutations in those with features of CdLS may be warranted. © 2013 Wiley Periodicals, Inc.
Role Experiences of Young Women: A Longitudinal Test of the Role Hiatus Hypothesis.

Using data from the National Longitudinal Study of the Education and Labor Market Experiences of Young Women, a test was made of the effect of three specific types of "role hiatus experiences" on young women's taste for paid employment and on their sex role beliefs. With controls for background variables and for beliefs and tastes measured while the young women were still in high school, it was found that the experiences of paid employment, occupational training, and college attendance before the onset of marriage and motherhood all altered tastes for paid employment but failed to affect sex role attitudes. While college and occupational training increased taste for paid employment, holding a job at this point in these young women's lives caused a decrease in this taste.