Miracle-dz/UniFAR-FTUs huggingface dataset:
A first step to an evidence-based talent identification program in the Netherlands; a research proposal

Talent identifications programs are developed for several sports in different countries around the world to improve the chance to excel during important sports events like the Olympics or World Championships . Not only elite sports at world class level but also the recreational level will benefit from talent identification programs. For a small country as The Netherlands, it is desirable to develop a good talent identification program to keep up with international level and to improve the connection between table tennis and recreational sports or non-athletes looking for a sport that fits them well. Because the key-factors which determine talent for table tennis are unknown, r esearch to get a scientific fundament for a talent identification system for table tennis sports is desirable. This article presents a long-term research project (PhD) which is set-up by the Dutch Table Tennis Federation (NTTB) together with Saxion University of Applied Sciences and IQ Healthcare of the Radboud University Nijmegen in The Netherlands . The main purpose of this project is to find sport-specific determinants which play a key-role in talent identification in table tennis using a combination of top-down and bottom-up approaches. Preliminary results from the top-down approach are already available from reliability and validity studies on the talent identification assessment (TIDA) which is used by the NTTB. Analysis shows mainly good reliability for the test items separately and for the TIDA as a whole. Concurrent validity is partly confirmed for the TIDA, however further analyse s are necessary. This research project can make an important step to an evidence-based talent identification program which benefits table tennis and other sports at elite and recreational level.
Simulated Estimates of Pre-Pregnancy and Gestational Diabetes Mellitus in the US: 1980 to 2008

Purpose To simulate national estimates of prepregnancy and gestational diabetes mellitus (GDM) in non-Hispanic white (NHW) and non-Hispanic black (NHB) women. Methods Prepregnancy diabetes and GDM were estimated as a function of age, race/ethnicity, and body mass index (BMI) using South Carolina live singleton births from 2004–2008. Diabetes risk was applied to a simulated population. Age, natality and BMI were assigned to women according to race- and age-specific US Census, Natality and National Health and Nutrition Examination Surveys (NHANES) data, respectively. Results From 1980–2008, estimated GDM prevalence increased from 4.11% to 6.80% [2.68% (95% CI 2.58%–2.78%)] and from 3.96% to 6.43% [2.47% (95% CI 2.39%–2.55%)] in NHW and NHB women, respectively. In NHW women prepregnancy diabetes prevalence increased 0.90% (95% CI 0.85%–0.95%) from 0.95% in 1980 to 1.85% in 2008. In NHB women from 1980 through 2008 estimated prepregnancy diabetes prevalence increased 1.51% (95% CI 1.44%–1.57%), from 1.66% to 3.16%. Conclusions Racial disparities in diabetes prevalence during pregnancy appear to stem from a higher prevalence of prepregnancy diabetes, but not GDM, in NHB than NHW.
The Importance of Pollinator Generalization and Abundance for the Reproductive Success of a Generalist Plant

Previous studies have examined separately how pollinator generalization and abundance influence plant reproductive success, but none so far has evaluated simultaneously the relative importance of these pollinator attributes. Here we evaluated the extent to which pollinator generalization and abundance influence plant reproductive success per visit and at the population level on a generalist plant, Opuntia sulphurea (Cactaceae). We used field experiments and path analysis to evaluate whether the per-visit effect is determined by the pollinator’s degree of generalization, and whether the population level effect (pollinator impact) is determined by the pollinator’s degree of generalization and abundance. Based on the models we tested, we concluded that the per-visit effect of a pollinator on plant reproduction was not determined by the pollinators’ degree of generalization, while the population-level impact of a pollinator on plant reproduction was mainly determined by the pollinators’ degree of generalization. Thus, generalist pollinators have the greatest species impact on pollination and reproductive success of O. sulphurea. According to our analysis this greatest impact of generalist pollinators may be partly explained by pollinator abundance. However, as abundance does not suffice as an explanation of pollinator impact, we suggest that vagility, need for resource consumption, and energetic efficiency of generalist pollinators may also contribute to determine a pollinator’s impact on plant reproduction.
Presence of Leptin in Chronic Periapical Lesions

INTRODUCTION Studies have shown the regulatory role of Leptin in bone formation, its expression in adipose tissue as well as increased levels in circulation following the adminstration of inflammatory stimuli such as lipopolysaccharides (LPS). However, there is little data evaluating the role of Leptin in inflammatory periapical lesions. The aim of this study was to evaluate the presence and concentration of Leptin in chronic periapical lesions. MATERIALS AND METHODS Chronic periapical lesions with different sizes were collected during periapical surgery of the mandibular molars from twenty patients and cultured for 72 hours. The ELISA method determined the concentration of Leptin in supernatant fluids of explants cultures. Statistical analysis was performed using non-parametric tests (Mann-Whitney U, Chi-Square and Spearman’s Correlation Coefficient). RESULTS Leptin was found in all samples with the average concentration of 405.55±102.98 (pg/mL). There was no significant correlation between the concentration of Leptin and BMI, and the diameters of lesions. CONCLUSION Leptin can be considered an inflammatory mediator and is likely to have a role during the early phases of dental periapical lesions.
Induced Autoimmunity to Heat Shock Proteins Elicits Glaucomatous Loss of Retinal Ganglion Cell Neurons via Activated T-Cell-Derived Fas-Ligand

Glaucomatous optic neuropathy causes blindness through the degeneration of retinal ganglion cells (RGCs) and their axons, which comprise the optic nerve. Glaucoma traditionally is associated with elevated intraocular pressure, but often occurs or may progress with intraocular pressure in the normal range. Like other diseases of the CNS, a subset of glaucoma has been proposed to involve an autoimmune component to help explain the loss of RGCs in the absence of elevated intraocular pressure. One hypothesis involves heat shock proteins (HSPs), because increased serum levels of HSP autoantibodies are prominent in some glaucoma patients with normal pressures. In the first direct support of this hypothesis, we found that HSP27 and HSP60 immunization in the Lewis rat induced RGC degeneration and axon loss 1–4 months later in vivo in a pattern with similarities to human glaucoma, including topographic specificity of cell loss. Infiltration of increased numbers of T-cells in the retina occurred much earlier, 14–21 d after HSP immunization, and appeared to be transient. In vitro studies found that T-cells activated by HSP immunization induced RGC apoptosis via the release of the inflammatory cytokine FasL, whereas HSP immunization induced activation of microglia cells and upregulation of the FasL receptor in RGCs. In summary, our results suggest that RGC degeneration in glaucoma for selected individuals likely involves failed immunoregulation of the T-cell-RGC axis and is thus a disturbance of both proapoptotic and protective pathways.
χ 2 and classical exact tests often wildly misreport significance ; the remedy lies in computers

If a discrete probability distribution in a model being tested for goodness-of-fit is not close to uniform, then forming the Pearson χ2 statistic can involve division by nearly zero. This often leads to serious trouble in practice — even in the absence of round-off errors — as the present article illustrates via numerous examples. Fortunately, with the now widespread availability of computers, avoiding all the trouble is simple and easy: without the problematic division by nearly zero, the actual values taken by goodnessof-fit statistics are not humanly interpretable, but black-box computer programs can rapidly calculate their precise significance. Supported in part by NSF Grant OISE-0730136 and an NSF Postdoctoral Research Fellowship Supported in part by a Research Fellowship from the Alfred P. Sloan Foundation Supported in part by an NSF Postdoctoral Research Fellowship and a Donald D. Harrington Faculty Fellowship 1
Detection of C3 in Diffuse Interstellar Clouds

The smallest polyatomic carbon chain, C3, has been identified in interstellar clouds (Av ~ 1 mag) toward ζ Ophiuchi, 20 Aquilae, and ζ Persei by detection of the origin band in its A 1Πu-X 1Σ electronic transition, near 4052 Å. Individual rotational lines were resolved up to J = 30, allowing the rotational-level column densities and temperature distributions to be determined. The inferred limits for the total column densities (~1-2 × 1012 cm-2) offer a strong incentive to laboratory and astrophysical searches for the longer carbon chains. Concurrent searches for C, C, and C were negative, but provide sensitive estimates for their maximum column densities.
Rubber Hand Illusion under Delayed Visual Feedback

Background Rubber hand illusion (RHI) is a subject's illusion of the self-ownership of a rubber hand that was touched synchronously with their own hand. Although previous studies have confirmed that this illusion disappears when the rubber hand was touched asynchronously with the subject's hand, the minimum temporal discrepancy of these two events for attenuation of RHI has not been examined. Methodology/Principal Findings In this study, various temporal discrepancies between visual and tactile stimulations were introduced by using a visual feedback delay experimental setup, and RHI effects in each temporal discrepancy condition were systematically tested. The results showed that subjects felt significantly greater RHI effects with temporal discrepancies of less than 300 ms compared with longer temporal discrepancies. The RHI effects on reaching performance (proprioceptive drift) showed similar conditional differences. Conclusions/Significance Our results first demonstrated that a temporal discrepancy of less than 300 ms between visual stimulation of the rubber hand and tactile stimulation to the subject's own hand is preferable to induce strong sensation of RHI. We suggest that the time window of less than 300 ms is critical for multi-sensory integration processes constituting the self-body image.
STUDI TENTANG ANTECEDENT SIKAP KONSUMEN TERHADAP KEPUTUSAN PEMBELIAN PADA I-COS COFFEE SHOP SEMARANG

Penelitian ini bertujuan untuk menganalisis faktor-faktor yang mempengaruhi sikap konsumen sebagai upaya mempengaruhi minat beli untuk meningkatkan keputusan pembelian konsumen. Permasalahan riset bersumber pada permasalahan tentang penurunan jumlah pelanggan dan pendapatan I-Cos Coffee shop Semarang, serta tidak terpenuhinya target jumlah pelanggan dan pendapatan coffee shop tersebut. I-Cos coffee shop adalah salah satu coffee shop lokal di Semarang yang memiliki konsep dan mutu yang tidak kalah dengan coffee shop asing. Dari permasalahan diatas yang mendasari dilakukan penelitian ini, yaitu untuk mengetahui faktor-faktor yang mempengaruhi sikap konsumen yang nantinya mempengaruhi minat beli dan akhirnya pada terbentuknya keputusan pembelian oleh konsumen. Dalam penelitian ini dikembangkan suatu model teoritis dengan mengajukan tujuh hipotesis yang akan diuji dengan menggunakan Structural Equation Model (SEM) dengan menggunakan software AMOS 18. Responden yang digunakan dalam penelitian ini diambil dari responden pelanggan I-cos coffee shop yang berjumlah 162 responden. Hasil penelitian ini menunjukkan bahwa sikap konsumen dapat ditingkatkan dengan meningkatkan pengalaman membeli, kualitas hubungan dan reputasi toko. Selanjutnya, sikap konsumen yang semakin tinggi akan mempengaruhi minat beli dan selanjutnya meningkatkan keputusan pembelian.
Expression of a novel neuropeptide, NVGTLARDFQLPIPNamide, in the larval and adult brain of Drosophila melanogaster

Advances in mass spectrometry and the availability of genomic databases made it possible to determine the peptidome or peptide content of a specific tissue. Peptidomics by nanoflow capillary liquid chromatography tandem mass spectrometry of an extract of 50 larval Drosophila brains, yielded 28 neuropeptides. Eight were entirely novel and encoded by five not yet annotated genes; only two genes had a homologue in the Anopheles gambiae genome. Seven of the eight peptides did not show relevant sequence homology to any known peptide. Therefore, no evidence towards the physiological role of these ‘orphan’ peptides was available. We identified one of the eight peptides, IPNamide, in an extract of the Drosophila adult brain as well. Next, specific antisera were raised to reveal the distribution pattern of IPNamide and other peptides from the same precursor, in larval and adult brains by means of whole‐mount immunocytochemistry and confocal microscopy. IPNamide immunoreactivity is abundantly present in both stages and a striking similarity was found between the distribution patterns of IPNamide and TPAEDFMRFamide, a member of the FMRFamide peptide family. Based on this distribution pattern, IPNamide might be involved in phototransduction, in processing sensory stimuli, as well as in controlling the activity of the oesophagus.
Emotional Intelligence, Spiritual Intelligence, Self-esteem and Self Control of Substance Abuse

Background: This study aims to investigate the relationship between emotional intelligence, spiritual intelligence and self-esteem, and self-control on men with addiction in rehabilitation centers of Tehran. Original Research Article Alaei et al.; INDJ, 9(4): 1-8, 2017; Article no.INDJ. 33461 2 Methods: This is a cross-sectional study sampling 200 men. From 12 treatment and rehabilitation centers in Tehran, 4 were randomly selected and fifty people from each center aged 20 to 50 with at least two years of addiction history were picked. Instruments used were: Eysenck Self-esteem Scale (ESI), Bradbury-Greaves Emotional Intelligence test, Abdullah Zadeh Spiritual Intelligence test and the Personal Control Scale (PCS). Results: A positive relationship was found between emotional intelligence, spiritual intelligence, self-esteem and substance abuse self-control (r=0.25, 0.21 and 0.24 at a level of confidence =0.001, respectively). Conclusion: Promotion of emotional intelligence, spiritual intelligence and self-esteem may prove useful in control of substance abuse in men.
Multiplicity for a nonlinear fourth-order elliptic equation in Maxwell-Chern-Simons vortex theory

We prove the existence of at least two solutions for a fourth order equation, which includes the vortex equations for the U(1) and CP(1) self-dual Maxwell-Chern-Simons models as special cases. Our method is variational, and it relies on an “asymptotic maximum principle” property for a special class of supersolutions to this fourth order equation.
A review of methods for leakage management in pipe networks

Leakage in water distribution systems is an important issue which is affecting water companies and their customers worldwide. It is therefore no surprise that it has attracted a lot of attention by both practitioners and researchers over the past years. Most of the leakage management related methods developed so far can be broadly classified as follows: (1) leakage assessment methods which are focusing on quantifying the amount of water lost; (2) leakage detection methods which are primarily concerned with the detection of leakage hotspots and (3) leakage control models which are focused on the effective control of current and future leakage levels. This paper provides a comprehensive review of the above methods with the objective to identify the current state-of-the-art in the field and to then make recommendations for future work. The review ends with the main conclusion that despite all the advancements made in the past, there is still a lot of scope and need for further work, especially in area of real-time models for pipe networks which should enable fusion of leakage detection, assessment and control methods.
Prickle and Strabismus form a functional complex to generate a correct axis during planar cell polarity signaling

Frizzled (Fz) signaling regulates the establishment of planar cell polarity (PCP). The PCP genes prickle (pk) and strabismus (stbm) are thought to antagonize Fz signaling. We show that they act in the same cell, R4, adjacent to that in which the Fz/PCP pathway is required in the Drosophila eye. We demonstrate that Stbm and Pk interact physically and that Stbm recruits Pk to the cell membrane. Through this interaction, Pk affects Stbm membrane localization and can cause clustering of Stbm. Pk is also known to interact with Dsh and is thought to antagonize Dsh by affecting its membrane localization. Thus our data suggest that the Stbm/Pk complex modulates Fz/Dsh activity, resulting in a symmetry‐breaking step during polarity signaling.
A Deep Neural Network approach for Voice Activity Detection in multi-room domestic scenarios

This paper presents a Voice Activity Detector (VAD) for multi-room domestic scenarios. A multi-room VAD (mVAD) simultaneously detects the time boundaries of a speech segment and determines the room where it was generated. The proposed approach is fully data-driven and is based on a Deep Neural Network (DNN) pre-trained as a Deep Belief Network (DBN) and fine-tuned by a standard error back-propagation method. Six different types of feature sets are extracted and combined from multiple microphone signals in order to perform the classification. The proposed DBN-DNN multi-room VAD (simply referred to as DBN-mVAD) is compared to other two NN based mVADs: a Multi-Layer Perceptron (MLP-mVAD) and a Bidirectional Long Short-Term Memory recurrent neural network (BLSTM-mVAD). A large multi-microphone dataset, recorded in a home, is used to assess the performance through a multi-stage analysis strategy comprising multiple feature selection stages alternated by network size and input microphones selections. The proposed approach notably outperforms the alternative algorithms in the first feature selection stage and in the network selection one. In terms of area under precision-recall curve (AUC), the absolute increment respect to the BLST-mVAD is 5.55%, while respect to the MLP-mVAD is 2.65%. Hence, solely the proposed approach undergoes the remaining selection stages. In particular, the DBN-mVAD achieves significant improvements: in terms of AUC and F-measure the absolute increments are equal to 10.41% and 8.56% with respect to the first stage of DBN-mVAD.
Induction of Split Anergy Conditions Natural Killer Cells to Promote Differentiation of Stem Cells through Cell–Cell Contact and Secreted Factors

In this paper, we provide evidence that anergized NK cells through secreted factors and direct cell–cell contact have the ability to induce differentiation of healthy dental pulp stem cells and stem cell of apical papillae as well as transformed oral squamous cancer stem cell (OSCSC) and Mia-Paca-2, poorly differentiated stem-like pancreatic tumors, resulting in their resistance to NK cell-mediated cytotoxicity. Induction of NK cell resistance and differentiation in the stem cells correlated with the increased expression of CD54, B7H1, and MHC class I, and mediated by the combination of membrane-bound or secreted IFN-γ and TNF-α from the NK cells since antibodies to both cytokines and not each one alone were able to inhibit differentiation or resistance to NK cells. Similarly, antibodies to both TNF-α and IFN-γ were required to prevent NK-mediated inhibition of cell growth, and restored the numbers of the stem cells to the levels obtained when stem cells were cultured in the absence of anergized NK cells. Interestingly, the effect of anti-IFN-γ antibody in the absence of anti-TNF-α antibody was more dominant for the prevention of increase in surface receptor expression since its addition abrogated the increase in CD54, B7H1, and MHC class I surface expression. Antibodies to CD54 or LFA-1 was unable to inhibit differentiation whereas antibodies to MHC class I but not B7H1 increased cytotoxicity of well-differentiated oral squamous carcinoma cells as well as OSCSCs differentiated by the IL-2 + anti-CD16 mAb-treated NK cells whereas it inhibited the cytotoxicity of NK cells against OSCSCs. Thus, NK cells may inhibit the progression of cancer by killing and/or differentiation of cancer stem cells, which severely halt cancer growth, invasion, and metastasis.
A synchronization method for implementing an OFDM system based on the TMS320C6416 DSP

This paper proposes a synchronization method for implementation of an OFDM system based on the TMS320C6416 DSP. The method is to meet the constraints of signal processing in real time conditions, and ensure the Quality of Services regarding the received signal quality. It is proven that the complexity of the proposed method is significantly reduced in comparison with the conventional one, and thus, the time constraint for synchronization is fulfilled. Moreover, the starting point of each OFDM frame stored in the receiver DSP buffers can be precisely detected. The data rate obtained by applying the Ping-Pong Buffer technique is significantly enhanced. Measurement results are compared with the theoretical results to validate our proposed mechanisms. Files and audio transfer are tested to demonstrate the performance of the implemented system.
Finding the Meanings of College Drinking: An Analysis of Fraternity Drinking Stories

College drinking has traditionally been studied from a public health perspective that attempts to quantify behavior as a means toward description, explanation, and intervention. This article offers a critical and cultural approach to understanding the meanings and functions of high-risk drinking and the ways in which those meanings are reproduced within the culture. Data were collected via an ethnographic study of fraternity members at a large midwestern university to explore the communication of excessive drinking norms. Viewed from various narrative and structural theories, the study examines collected drinking stories as a source for analyzing the construction of meanings surrounding drunkenness for the fraternity subculture. Five themes emerged as functions of drunkenness for the culture. Implications for prevention are discussed.
Invisiboard: maximizing display and input space with a full screen text entry method for smartwatches

The small displays of smartwatches make text entry difficult and time consuming. While text entry rates can be increased, this continues to occur at the expense of available screen display space. Soft keyboards can easily use half the display space of tiny-screened devices. To combat this problem, we present Invisiboard: an invisible text entry method using the entire display for both text entry and display simultaneously. Invisiboard combines a numberpad-like layout with swipe gestures. This maximizes input target size, provides a familiar layout, and maximizes display space. Through this, Invisiboard achieves entry rates comparable or even faster than an existing research baseline. A user study with 12 participants writing 3264 words revealed an entry rate of 10.6 Words Per Minute (WPM) after 30 minutes, 7% faster than ZoomBoard. Furthermore, with nominal training, some participants demonstrated entry rates of over 30 WPM.