Miracle-dz/UniFAR-FTUs huggingface dataset:
Self-Stabilizing Mutual Exclusion Under Arbitrary Scheduler

A self-stabilizing algorithm, regardless of the initial system state, converges in finite time to a set of states that satisfy a legitimacy predicate. The mutual exclusion problem is fundamental in distributed computing, since it allows processors competing to access a shared resource to be able to synchronize and get exclusive access to the resource (i.e. execute their critical section). It is well known that providing self-stabilization in general uniform networks (e.g. anonymous rings of arbitrary size) can only be probabilistic. However, all existing uniform probabilistic self-stabilizing mutual exclusion algorithms designed to work under an unfair distributed scheduler (that may choose processors to execute their code in an arbitrary manner) suffer from the following common drawback: once stabilized, there exists no upper bound on time between two successive executions of the critical section at a given processor. In this paper, we present the first self-stabilizing algorithm that guarantees such a bound (O(n 3 ), where n is the network size) while working using an unfair distributed scheduler. Our algorithm works in an anonymous unidirectional ring of any size and has a polynomial expected stabilization time. Received 24 May 2002; revised 17 October 2003
Clinical problems of colorectal cancer and endometrial cancer cases with unknown cause of tumor mismatch repair deficiency ( suspected Lynch syndrome )

License. The full terms of the License are available at http://creativecommons.org/licenses/by-nc/3.0/. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. Permissions beyond the scope of the License are administered by Dove Medical Press Limited. Information on how to request permission may be found at: http://www.dovepress. com/permissions.php The Application of Clinical Genetics 2014:7 183–193 The Application of Clinical Genetics Dovepress
UAV Teams in Emergency Scenarios: A Summary of the Work within the Project PRISMA

In recent years autonomous robots, and Unmanned Aerial Vehicles (UAVs) in particular, are becoming always more important in the context of emergency scenarios, being able to anticipate the actions of human operators and to support them during rescue operations. In this context, the investigation of strategies for the autonomous control of UAVs, for the development of Human-Swarm Interfaces and for the coverage of large areas is crucial. All these aspects have been analyzed within the Italian project PRISMA, and they will be here summarized.
Assessment of electroporation by flow cytometry.

BACKGROUND Electroporation accomplishes transient permeabilization of cells and thus aids in the uptake of drugs. The method has been employed clinically in the treatment of dermatological tumors with bleomycin. The conditions of electroporation are still largely empirical and information is lacking as to the interrelationships among voltage pulse height, pulse number and toxicity, cell permeation, drug uptake, and effects on drug toxicity. We used propidium iodide (PI) and flow cytometry to define cell permeation into cytoplasmic and nuclear compartments to determine the improvements of drug toxicity that can be accomplished by electroporation. METHODS Human squamous carcinoma cells of defined TP53 status and normal human epithelial cells were subjected to electroporation using a square wave pulse generator in the range of 0-5,000 V/cm. Flow cytometry served to establish entry of the drug reporter, PI, into the cytoplasm and nucleus. A dye staining method served to establish cell survival and to determine the toxicity of bleomycin alone, electroporation alone, and electroporation with bleomycin. RESULTS The electric field intensity (EFI) required to produce 50% permeabilization (EP(50)) is cell type dependent. The EP(50) varied from 1,465 to 2,027 V/cm. An EFI below 900 V/cm is growth stimulatory whereas an EFI in excess of 1,000 V/cm is growth inhibitory. An EFI of 1,000 V/cm is sufficient to increase bleomycin toxicity by a factor of 2-3. A differential electroporation efficiency is observed between normal and tumor cells. CONCLUSIONS Tumor cells can be targeted preferentially at electroporation voltages where normal cells are less permeable.
Interactions among Amazon land use, forests and climate: prospects for a near-term forest tipping point

Some model experiments predict a large-scale substitution of Amazon forest by savannah-like vegetation by the end of the twenty-first century. Expanding global demands for biofuels and grains, positive feedbacks in the Amazon forest fire regime and drought may drive a faster process of forest degradation that could lead to a near-term forest dieback. Rising worldwide demands for biofuel and meat are creating powerful new incentives for agro-industrial expansion into Amazon forest regions. Forest fires, drought and logging increase susceptibility to further burning while deforestation and smoke can inhibit rainfall, exacerbating fire risk. If sea surface temperature anomalies (such as El Niño episodes) and associated Amazon droughts of the last decade continue into the future, approximately 55% of the forests of the Amazon will be cleared, logged, damaged by drought or burned over the next 20 years, emitting 15–26 Pg of carbon to the atmosphere. Several important trends could prevent a near-term dieback. As fire-sensitive investments accumulate in the landscape, property holders use less fire and invest more in fire control. Commodity markets are demanding higher environmental performance from farmers and cattle ranchers. Protected areas have been established in the pathway of expanding agricultural frontiers. Finally, emerging carbon market incentives for reductions in deforestation could support these trends.
GigaHash: scalable minimal perfect hashing for billions of urls

A minimal perfect function maps a static set of n keys on to the range of integers {0,1,2,. ,n - 1}. We present a scalable high performance algorithm based on random graphs for constructing minimal perfect hash functions (MPHFs). For a set of n keys, our algorithm outputs a description of h in expected time O(n). The evaluation of h(x) requires three memory accesses for any key x and the description of h takes up 0.89n bytes (7.13n bits). This is the best (most space efficient) known result to date. Using a simple heuristic and Huffman coding, the space requirement is further reduced to 0.79n bytes (6.86n bits). We present a high performance architecture that is easy to parallelize and scales well to very large data sets encountered in internet search applications. Experimental results on a one billion URL dataset obtained from Live Search crawl data, show that the proposed algorithm (a)finds an MPHF for one billion URLs in less than 4 minutes, and (b) requires only 6.86 bits/key for the description of h.
Prognostic significance of functional mitral regurgitation after a first non-ST-segment elevation acute coronary syndrome.

AIMS The development of mitral regurgitation (MR) after an acute myocardial infarction (AMI) is a recognized and frequent complication and its negative impact on survival has been observed. However, few data exist regarding MR after non-ST-segment elevation acute coronary syndrome (NSTSEACS). Our aim was to investigate the incidence, clinical predictors, and prognostic implications of MR in the setting of NSTSEACS. METHODS AND RESULTS We studied 300 consecutive patients (71.7% men, mean age 66.9+/-13 years) admitted to our coronary care unit for an NSTSEACS. Every patient underwent an echocardiographic study during the first week after the index NSTSEACS and was clinically followed up. MR was detected in 42% (126 patients; 88 men, mean age 71.3+/-11 years). Mean follow-up was 425.6+/-194.8 days. Only age and left ventricular (LV) ejection fraction (EF) were found as independent markers of the development of MR; no variable was found as an independent predictor of in-hospital mortality and only MR was found as an independent predictor of long-term outcome. CONCLUSION MR is frequent after an NSTSEACS. Age and a low LV EF are factors associated to its development. The presence and degree of MR confer a worse long-term prognosis to patients after a first NSTSEACS. Thus, the presence of MR should be specifically assessed in every patient after an NSTSEACS.
Aldosterone-Specific Activation of Cardiomyocyte Mineralocorticoid Receptor In Vivo

Inappropriate mineralocorticoid receptor (MR) activation is involved in cardiac diseases. Whether and how aldosterone is involved in the deleterious effects of cardiac mineralocorticoid activation is still unclear. Mice overexpressing MR in cardiomyocytes and their controls were treated for 7 days with aldosterone, and cardiac transcriptome was analyzed. Aldosterone regulated 265 genes in cardiomyocyte-targeted MR overexpression mice. Forty three of these genes were also differentially expressed between untreated cardiomyocyte-targeted MR overexpression and controls mice, thus representing putative aldosterone-regulated genes in cardiomyocytes. Among these genes, we focused on connective tissue growth factor (CTGF). In vivo, in cardiomyocyte-targeted MR overexpression mice, aldosterone (but not corticosterone) induced CTGF expression (mRNA and protein) in cardiomyocytes. Ex vivo, aldosterone induced the binding of mineralocorticoid receptor to CTGF promoter and increased the expression of its transcript. Aldosterone induction of CTGF synthesis in cardiomyocytes seems pathologically relevant as the increase in CTGF observed in a model of heart failure (transverse aortic constriction) in rats was prevented by eplerenone, a mineralocorticoid receptor blocker. This study demonstrates that aldosterone specifically regulates gene expression in cardiomyocytes despite large prevalence of glucocorticoids in plasma.
Global mRNA Degradation during Lytic Gammaherpesvirus Infection Contributes to Establishment of Viral Latency

During a lytic gammaherpesvirus infection, host gene expression is severely restricted by the global degradation and altered 3′ end processing of mRNA. This host shutoff phenotype is orchestrated by the viral SOX protein, yet its functional significance to the viral lifecycle has not been elucidated, in part due to the multifunctional nature of SOX. Using an unbiased mutagenesis screen of the murine gammaherpesvirus 68 (MHV68) SOX homolog, we isolated a single amino acid point mutant that is selectively defective in host shutoff activity. Incorporation of this mutation into MHV68 yielded a virus with significantly reduced capacity for mRNA turnover. Unexpectedly, the MHV68 mutant showed little defect during the acute replication phase in the mouse lung. Instead, the virus exhibited attenuation at later stages of in vivo infections suggestive of defects in both trafficking and latency establishment. Specifically, mice intranasally infected with the host shutoff mutant accumulated to lower levels at 10 days post infection in the lymph nodes, failed to develop splenomegaly, and exhibited reduced viral DNA levels and a lower frequency of latently infected splenocytes. Decreased latency establishment was also observed upon infection via the intraperitoneal route. These results highlight for the first time the importance of global mRNA degradation during a gammaherpesvirus infection and link an exclusively lytic phenomenon with downstream latency establishment.
Face Searching and Matching Using Gray Scale Diagonal Square Matrix

----------------------------------------------------------------------ABSTRACT-------------------------------------------------------------------- This paper presents a novel approach in face digital image searching and matching. The given key image is converted into gray scale image and after that a matrix is computed with gray scale values of the key image. Then we are collecting the diagonal key elements for diagonal searching key sequence. Using Pair wise sequence alignment we are trying to match the key with available images in the large data base of collection of faces. Initially we discussed various techniques used in digital image searching and matching in this paper. This new algorithm Diagonal matrix is a new algorithm for all face images searching and matching. Face recognition is very essential in the field of criminology. Face Image searching and matching are very difficult task in image processing; there are several algorithms for face image matching. But still needs more optimization for image matching. Using this new approach we can match criminal photo from a large database. Face Image recognition, feature extraction and pattern matching needs improvements in Image processing. There are several methods for Face image searching and matching, but we need new optimized technique for image searching and matching. This new Diagonal matrix approach is tried to give optimized solution in Face digital image matching.
Adynamic bone disease: clinical and therapeutic implications

Purpose of reviewAdynamic bone disease has recently been associated with increased risk of vascular calcification. This review focuses on the emerging data in adynamic bone disease, its clinical consequences and therapeutic implications. Recent findingsThere is a lack of good biochemical markers of parathyroid status, bone formation and reabsorption to allow a secure diagnosis of bone disease. Recent data have suggested a possible link between bone activity and vascular calcification. Cardiovascular calcification is an independent predictor of mortality. Adynamic bone is associated with a very low capacity of bone to incorporate calcium in the bone compartment and inability to handle an extra calcium load. A positive association between vascular calcifications and low bone turnover has been suggested. Calcium-containing phosphate binders, active vitamin D therapy and high calcium dialysate may enhance vascular calcifications in the presence of adynamic bone disease. SummaryThere is recent evidence suggesting a negative impact of calcium load in the progression of vascular calcification in dialysis patients with chronic kidney disease stage 5 with adynamic bone disease. The current therapeutic approach to these patients should focus on reduction of calcium and vitamin D load to restore parathyroid activity.
Sleep Quality and Spiritual Well-Being in Hemodialysis Patients

Background: Sleep disorders are considered as one of the most important problems in hemodialysis patients, making their everyday life a serious hazard. Sleep quality of hemodialysis patients and consequences of sleep disorders on other aspects of health such as spiritual well-being are important issues. Objectives: This study examined the relationship between spiritual well-being and quality of sleep in hemodialysis patients in Isfahan, Iran. Patients and Methods: This study was a correlation research, carried out on 190 hemodialysis patients. Data collection Questionnaires included demographic forms, Pittsburgh sleep quality index (PSQI), and Ellison and Paloutzian spiritual well-being scale. Data were analyzed using descriptive and inferential statistics (Pearson correlation and linear regression analysis) at P < 0.05 significance level, by SPSS software version 18. Results: Of 190 study participants, 163 (85.78%) with scores more than five index had sleep disturbances and 27 (14.12%) had no sleep disturbance; 3 (1.52%) had mild, 163 (85.78%) moderate, and 24 (12.30%) good spiritual health conditions. Pearson correlation test showed significant relationship between the sleep quality items of Pittsburg and spiritual well-being (P < 0.04, r = 0.149). Through the regression analyses of spiritual health, family, education, financial status, marital status, occupation, and use of sleep medication, the predictive power of these variables was found 0.417% and prediction of spiritual well-being was more than others (ß = 0.209). Conclusions: Considering bed as one of the most vital physical, mental, and emotional needs, it is very important in mental and spiritual well-being of hemodialysis patients as an influencing factor in mental relaxation and reducing disease tensions. Paying attention to sleep quality and spiritual well-being components of hemodialysis patients in formulating and promoting healthcare programs is recommended.
Information retrieval in falktales using natural language processing

Our aim is to extract information about literary characters in unstructured texts. We employ natural language processing and reasoning on domain ontologies. The first task is to identify the main characters and the parts of the story where these characters are described or act. We illustrate the system in a scenario in the folktale domain. The system relies on a folktale ontology that we have developed based Propp's model for folktales morphology.
A Tennis Ball Tracking Algorithm for Automatic Annotation of Tennis Match

Several tennis ball tracking algorithms have been reported in the literature. However, most of them use high quality video and multiple cameras, and the emphasis has been on coordinating the cameras, or visualising the tracking results. In this paper, we propose a tennis ball tracking algorithm for low quality off-air video recorded with a single camera. Multiple visual cues are exploited for tennis candidate detection. A particle filter with improved sampling efficiency is used to track the tennis candidates. Experimental results show that our algorithm is robust and has a tracking accuracy that is sufficiently high for automatic annotation of tennis matches.
The digital playing desk: a case study for augmented reality

To compare the advantages and disadvantages of a "natural user interface" a field study was carried out at the largest computer fair in Switzerland. Four different computer stations were presented to the public: 1) with a command language; 2) with a mouse; 3) with a touch screen; and 4) a digital playing desk (DPD) interface. With the DPD the user has to play a board game by moving a real chip an a virtual playing field against a virtual player. The task was to win the computer game. The reactions of the virtual player were simulated by "emoticons" as colored comic strip pictures with a corresponding sound pattern. We investigated the effects of these four different interaction techniques. Results of the inquiry show that the touch screen station was rated as the easiest to use interaction technique, followed by the mouse, DPD interface and the command language interface. From the results of the field test we conclude that the DPD as a graspable user interface with emotional, non-verbal feedback is a promising candidate for the next generation of dialog techniques.
DNA barcodes of the native ray‐finned fishes in Taiwan

Species identification based on the DNA sequence of a fragment of the cytochrome c oxidase subunit I gene in the mitochondrial genome, DNA barcoding, is widely applied to assist in sustainable exploitation of fish resources and the protection of fish biodiversity. The aim of this study was to establish a reliable barcoding reference database of the native ray‐finned fishes in Taiwan. A total of 2993 individuals, belonging to 1245 species within 637 genera, 184 families and 29 orders of ray‐finned fishes and representing approximately 40% of the recorded ray‐finned fishes in Taiwan, were PCR amplified at the barcode region and bidirectionally sequenced. The mean length of the 2993 barcodes is 549 bp. Mean congeneric K2P distance (15.24%) is approximately 10‐fold higher than the mean conspecific one (1.51%), but approximately 1.4‐fold less than the mean genetic distance between families (20.80%). The Barcode Index Number (BIN) discordance report shows that 2993 specimens represent 1275 BINs and, among them, 86 BINs are singletons, 570 BINs are taxonomically concordant, and the other 619 BINs are taxonomically discordant. Barcode gap analysis also revealed that more than 90% of the collected fishes in this study can be discriminated by DNA barcoding. Overall, the barcoding reference database established by this study reveals the need for taxonomic revisions and voucher specimen rechecks, in addition to assisting in the management of Taiwan's fish resources and diversity.
Bloom of resident antibiotic-resistant bacteria in soil following manure fertilization

Significance The increasing prevalence of antibiotic-resistant bacteria is one of the most serious threats to public health in the 21st century. One route by which resistance genes enter the food system is through amendment of soils with manure from antibiotic-treated animals, which are considered a reservoir of such genes. Previous studies have associated application of pig manure with the dispersal of sulfonamide-resistance genes to soil bacteria. In this study, we found that dairy cow manure amendment enhanced the proliferation of resident antibiotic-resistant bacteria and genes encoding β-lactamases in soil even though the cows from which the manure was derived had not been treated with antibiotics. Our findings provide previously unidentified insight into the mechanism by which amendment with manure enriches antibiotic-resistant bacteria in soil. The increasing prevalence of antibiotic-resistant bacteria is a global threat to public health. Agricultural use of antibiotics is believed to contribute to the spread of antibiotic resistance, but the mechanisms by which many agricultural practices influence resistance remain obscure. Although manure from dairy farms is a common soil amendment in crop production, its impact on the soil microbiome and resistome is not known. To gain insight into this impact, we cultured bacteria from soil before and at 10 time points after application of manure from cows that had not received antibiotic treatment. Soil treated with manure contained a higher abundance of β-lactam–resistant bacteria than soil treated with inorganic fertilizer. Functional metagenomics identified β-lactam–resistance genes in treated and untreated soil, and indicated that the higher frequency of resistant bacteria in manure-amended soil was attributable to enrichment of resident soil bacteria that harbor β-lactamases. Quantitative PCR indicated that manure treatment enriched the blaCEP-04 gene, which is highly similar (96%) to a gene found previously in a Pseudomonas sp. Analysis of 16S rRNA genes indicated that the abundance of Pseudomonas spp. increased in manure-amended soil. Populations of other soil bacteria that commonly harbor β-lactamases, including Janthinobacterium sp. and Psychrobacter pulmonis, also increased in response to manure treatment. These results indicate that manure amendment induced a bloom of certain antibiotic-resistant bacteria in soil that was independent of antibiotic exposure of the cows from which the manure was derived. Our data illustrate the unintended consequences that can result from agricultural practices, and demonstrate the need for empirical analysis of the agroecosystem.