Miracle-dz/UniFAR-FTUs huggingface dataset:
Role of Serial Phlebotomy in the Management of Blunt Solid Organ Injury in Adults

Background: The management of blunt spleen and liver trauma has become increasingly nonoperative. There is no consensus on timing or duration of serial hemoglobin and hematocrit monitoring in this patient population. Objective: This study examined the clinical utility of serial hemoglobin and hematocrit monitoring. We hypothesized that most interventions occur early in the hospital course, based on hemodynamic instability or physical examination findings rather than serial monitoring. Methods: We conducted a retrospective cohort study of adult trauma patients with blunt spleen or liver injury from November 2014 through June 2019 at our Level II trauma center. Interventions were classified as no intervention, surgical intervention, angioembolization, or packed red blood cell transfusion. Demographics, length of stay, total blood draws, laboratory values, and clinical triggers preceding intervention were reviewed. Results: A total of 143 patients were studied, of whom 73 (51%) received no intervention, 47 (33%) received an intervention within 4 hr of presentation, and 23 (16%) had interventions beyond 4 hr. Of these 23 patients, 13 received an intervention based on phlebotomy results alone. Most of these patients (n = 12, 92%) received blood transfusion without further intervention. Only one patient underwent operative intervention based on serial hemoglobin results on hospital day 2. Conclusion: The majority of patients with these injury patterns either require no intervention or declare themselves promptly after arrival. Serial phlebotomy after initial triage and intervention may add little value in the management of blunt solid organ injury.
Sports Medicine Curricular Recommendations for Undergraduate Medical Education

Abstract Sports medicine is a unique field encompassing many specialties and aspects of medicine. While musculoskeletal medicine is a significant aspect of sports medicine, the breadth of sports medicine extends beyond the musculoskeletal system and includes the spectrum of care for the patient who is or desires to be physically active. This article provides recommendations for sports medicine education in undergraduate medical education. The framework highlighting these recommendations uses domains of competence. Entrustable professional activities, measures that are endorsed by the Association of American Medical Colleges, were matched to domains of competence to provide objective markers of achievement. In addition to recommended sports medicine educational content, there should be consideration of both methods of assessment and implementation catered to each individual institution’s needs and resources. These recommendations may serve as a guide for medical educators and institutions pursing optimization of sports medicine education.
THE HIGH TEMPERATURE SUPERCONDUCTIVITY TEM TRANSIENT MAGNETIC FIELD PSEUDO-2D INVERSION AND ITS APPLICATION EFFECT

Theory and practice show that the observation of the transient magnetic field in the TEM has more advantages than that of the induced EMF.With the application and improvement of the high-temperature superconducting technology,the direct observation of transient magnetic field signal has become a reality in the TEM.However,the retrieve interpretation method for transient magnetic field data has become an urgent problem.In this paper,drawing on the interpretation method of the induced EMF,the authors made an overall explanation of the definition of apparent resistivity based on a study of the transient magnetic field and probed into the TEM transient magnetic field for PSEUDO-2D inverse technology.From the theoretical model and the measured data,the authors have verified the practicality of the method,which can provide technical support for the development of the high-temperature superconductor TEM method.
Estimation for the intensity of beam loss by the optical fiber based Cherenkov beam loss monitor at SACLA

From the issues of radiation safety and radiation damage of accelerator equipments, it is useful to detect the beam loss immediately at high-energy and high intensity particle accelerator facilities. In the undulator section of Spring-8 Angstrom Compact free electron LAser (SACLA) [1], beam loss monitors have been installed in order to control beam losses and to prevent demagnetization of permanent magnets due to electron hitting [2]. Since the commissioning phase of SACLA, this monitor has been successfully working. This beam loss monitor consists of a quartz fiber with 400 μm core diameter and a photomultiplier tube (PMT) which is connected with the upstream end of the fiber. The Cherenkov radiation which is produced in the fiber due to the passing of secondary electrons and positrons (Cherenkov emitters) is detected by the photomultiplier tube. With the detection time of the monitor signals, the position of the beam loss point can be measured. In addition, the use of two monitors with different gains allows measuring intensity of the beam loss over the wide dynamic range. While it is expected that the waveform of the monitor signal corresponds to the spatial distribution of the electron flux or absorbed dose due to the beam loss, if this monitor is used for the beam loss control, it is necessary to calibrate the magnitude of the monitor signal to a value such as the number of electrons or the absorbed dose in order to set an appropriate threshold level. In this study, the electron beam loss was measured by the beam loss monitor and thermo luminescent dosimeters (TLD), and the correlation among the signal of the beam loss monitor, the absorbed dose and electron flux was investigated.
Extensions to Study Electrochemical Interfaces - A Contribution to the Theory of Ions

In the present study an alternative model allows the extension of the DebyeHückel Theory (DHT) considering time dependence explicitly. From the Electro-Quasistatic approach (EQS) done in earlier studies time dependent potentials are suitable to describe several phenomena especially conducting media as well as the behaviour of charged particles in arbitrary solutions acting as electrolytes. This leads to a new formulation of the meaning of the nonlinear Poisson-Boltzmann Equation (PBE). If a concentration and/or flux gradient of particles is considered the original structure of the mPBE will be modified leading to a new nonlinear partial differential equation (nPDE) of the third order. It is shown how one can derive classes of solutions for the potential function analytically by application of an algebraic method. The benefit of the mathematical tools used here is the fact that closed-form solutions can be calculated without any numerical approximations.
Evenness mediates the global relationship between forest productivity and richness

1. Biodiversity is an important component of natural ecosystems, with higher species richness often correlating with an increase in ecosystem productivity. Yet, this relationship varies substantially across environments, typically becoming less pronounced at high levels of species richness. However, species richness alone cannot reflect all important properties of a community, including community evenness, which may mediate the relationship between biodiversity and productivity. If the evenness of a community correlates negatively with richness across forests globally, then a greater number of species may not always increase overall diversity and productivity of the system. Theoretical work and local empirical studies have shown that the effect of evenness on ecosystem functioning may be especially strong at high richness levels, yet the consistency of this remains untested at a global scale.
Design of a Closed-Loop Wireless Power Transfer System for an Implantable Drug Delivery Device

Active implantable medical devices (AIMDs) have seen a significant increase in popularity in recent years due to their ability to provide continuous therapy unobtrusively. One of the key challenges in developing next-generation AIMDs is the design of a safe and reliable wireless power transfer (WPT) system. Standard commercial WPT components are not optimized to deliver small amounts of power or to work with other than small air gaps. We developed a near-field resonant inductive coupling (NRIC) WPT system with closed-loop real-time control, based on the commercial off-the-shelf (COTS) components and leveraging the already integrated wireless communication system. The system was used to recharge a secondary battery and power supply the nanochannel delivery system (nDS). We tested the system’s robustness by varying the coil spacing to a maximum of 20 mm, and by misaligning the coils laterally and angularly up to 8 mm and 12°, respectively. We performed these tests by simulating battery charging from 2.8 to 4.1 V and we tested four coils, from 6 to 19 mm in diameter, to evaluate the best tradeoff between effectiveness and miniaturization. Finally, we recharged the selected battery for two distances, 2.5 and 6.5 mm. The results show that the 17- and 19-mm coils have the highest peak efficiencies of 31.3% and 32.3% (26% and 26.3% on average), respectively, and provide a complete and reliable battery recharge in less than 5 h while keeping the receiver coil temperature within 2°C.
First report of leaf spot disease in Bischofia javanica Blume caused by Pseudopestalotiopsis thailandica in India

Bischofia javanica Blume is a forest tree species belongs to the family phyllanthaceae which grows all over the world. During the survey of silviculture nurseries of B. javanica in Lataguri, West Bengal on March 2022, seedlings were found affected by a new leaf spot disease. The causal organism was identified as Pseudopestalotiopsis thailandica (Accession No. NR_164472.1). Pathogenicity test carried out on B. javanica showed that the isolated fungus was found infecting the plant from which it was isolated. The fungal pathogen was re-isolated from the infected leaves and confirmed by its morphological features. Scanning of literature has revealed Pseudopestalotiopsis thailandica as a new host record on B. javanica and this is the first report from India. The findings from this study could be beneficial in proper disease monitoring, and effective management purposes of seedlings of B. javanica.
Evolving SPIDe Towards the Integration of Requirements Elicitation in Interaction Design

Among the various interaction (re)design processes and approaches, SPIDe is a semio-participatory methodological process inspired by communication-centered design. However, the development of computational solutions is not limited to interaction design. Requirements elicitation is also an integral part of this process. Some SPIDe studies indicated that it is also possible to raise requirements through its application due to its participatory characteristics. This article presents an investigation on the feasibility of SPIDe when applied to requirements elicitation integrated with interaction design, presenting an exploratory case study. From the perspective of different experts, we explain the strengths and needs of SPIDe in supporting requirements elicitation integrated into interaction design. Data were collected through logbooks, semi-structured interviews, and the TAM questionnaire and then analyzed through thematic analysis. The results show that the SPIDe use for requirements elicitation integrated into the interaction design is feasible. Furthermore, they indicated that possible improvements in SPIDe could benefit the development of the computational solutions considering a single application of SPIDe to obtain data for interaction design and requirements elicitation integrated.
SSR marker-based genetic diversity and marker-trait association analysis in aromatic rice (Oryza sativa) landraces

The present study on SSR marker-based genetic diversity and marker-trait association analysis in aromatic rice (Oryza sativa L.) landraces was carried out at R. H. Richharia Research Laboratory, Indira Gandhi Krishi Vishwavidyalaya, Raipur, Chhattisgarh during 2020. A total of 25 PCR-based simple sequence repeats (SSR) markers were evaluated in a set of 90 aromatic rice landraces along with 6 checks which includes 1 non-aromatic and 5 aromatic check varieties. Phenotypic data for marker-trait association analysis were taken for 24 yield attributing traits. Polymorphic Information Content (PIC) value ranged from 0.52 (RM316) to 0.79 (RM553) with a mean of0.69 which reveals that all the markers used in this study were highly informative and useful for diversity analysis of a wide range of genotypes. Unweighted Pair Group Method with Arithmetic Mean (UPGMA) and Rho’s similarity based cluster analysis revealed that all 5 aromatic check varieties falls in one cluster while the 1 non-aromatic check variety (Mahamaya) forms a separate cluster. Mixed linear model (MLM) was applied to perform genome-wide association mapping where 41 significant marker-trait associations were observed for 24 yield attributing traits. The potential markers identified in the study may provide new opportunities for rice breeder to improve yield and its attributing traits through marker assisted selection approach.
Multi-Targeting Neuroprotective Effects of Syzygium aromaticum Bud Extracts and Their Key Phytocompounds against Neurodegenerative Diseases

Alzheimer’s disease (AD) is a neurodegenerative disease that causes a gradual loss of normal motor and cognitive function. The complex AD pathophysiology involves various factors such as oxidative stress, neuroinflammation, amyloid-beta (Aβ) aggregation, disturbed neurotransmission, and apoptosis. The available drugs suffer from a range of side effects and are not able to cover different aspects of the disease. Therefore, finding a safer therapeutic approach that can affect multiple targets at a time is highly desirable. In the present study, the underlying neuroprotective mechanism of an important culinary spice, Syzygium aromaticum (Clove) extract, and major bioactive compounds were studied in hydrogen peroxide-induced oxidative stress in human neuroblastoma SH-SY5Y cell lines as a model. The extracts were subjected to GC-MS to identify important bioactive components. The extracts and key bio-actives reduced reactive oxygen species (ROS), restored mitochondrial membrane potential (MMP), and provided neuroprotection from H2O2-induced oxidative stress in cell-based assays due to the antioxidant action. They also reduced lipid peroxidation significantly and restored GSH content. Clove extracts have also displayed anti-acetylcholinesterase (AChE) activity, anti-glycation potential, and Aβ aggregation/fibrilization inhibition. The multitarget neuroprotective approach displayed by Clove makes it a potential candidate for AD drug development.
Matching Knowledge Graphs in Entity Embedding Spaces: An Experimental Study

Entity alignment (EA) identifies equivalent entities that locate in different knowledge graphs (KGs), and has attracted growing research interests over the last few years with the advancement of KG embedding techniques. Although a pile of embedding-based EA frameworks have been developed, they mainly focus on improving the performance of entity representation learning, while largely overlook the subsequent stage that matches KGs in entity embedding spaces. Nevertheless, accurately matching entities based on learned entity representations is crucial to the overall alignment performance, as it coordinates individual alignment decisions and determines the global matching result. Hence, it is essential to understand how well existing solutions for matching KGs in entity embedding spaces perform on present benchmarks, as well as their strengths and weaknesses. To this end, in this article we provide a comprehensive survey and evaluation of matching algorithms for KGs in entity embedding spaces in terms of effectiveness and efficiency on both classic settings and new scenarios that better mirror real-life challenges. Based on in-depth analysis, we provide useful insights into the design trade-offs and good paradigms of existing works, and suggest promising directions for future development.
Freezing Does Not Alter Sperm Telomere Length despite Increasing DNA Oxidation and Fragmentation

Correlations were reported between sperm telomere length (STL) and male fertility, sperm DNA fragmentation, and oxidation. Sperm freezing is widely used for assisted reproductive techniques, fertility preservation, and sperm donation. However, its impact on STL remains unknown. For this study, semen surplus from patients who underwent routine semen analysis were used. The impact of slow freezing on STL was analyzed by performing qPCR before and after freezing. Sperm populations with different STL were evaluated using Q-FISH. The relationship between sperm DNA oxidation, DNA fragmentation, and STL was assessed in fresh and frozen sperm samples. No significant impact of slow freezing on STL was observed, neither measured by qPCR nor Q-FISH. However, Q-FISH allowed for the distinguishing of sperm populations with different STLs within individual sperm samples. Slow freezing induced different STL distributions for some of the analyzed sperm samples, but no correlation was found between STL and sperm DNA fragmentation or oxidation. Slow freezing does not alter STL despite increasing sperm DNA oxidation and fragmentation. As STL alterations could be transmitted to offspring, the lack of impact of the slow freezing method on STL ensures the safety of this procedure.
Uncertainty analysis of future summer monsoon duration and area over East Asia using a multi-GCM/multi-RCM ensemble

This study examines the spatiotemporal characteristics of the summer monsoon rainy season over East Asia using six regional climate models (RCMs) participating in the Coordinated Regional Domain Experiment (CORDEX) East Asia Phase II project. The framework combining multiple global climate models (GCMs) with multiple RCMs produces a larger spread in summer monsoon characteristics than driving GCMs only, enabling a better quantification of uncertainty factors. On average, the RCM simulations reproduce the observed summer monsoon duration and area better than the corresponding boundary GCMs, implying the added values of downscaling. Both the area and duration of the East Asian summer monsoon are projected to increase by the late 21st century, more strongly in high emission scenarios than in low emission scenarios, particularly in China. Different responses between scenarios, which indicate warming mitigation benefits, only become significant in the late 21st century due to large intersimulation uncertainties. Analysis of variance results show that uncertainty in future monsoon area and duration is larger between boundary GCMs than between RCMs over East Asia and its coastal subregions. A strong intersimulation relationship between RCMs and GCMs supports that boundary GCMs substantially diversify downscaled RCM projections through different climate sensitivities. Furthermore, the distinct subregional responses in future monsoon area and duration emphasize the importance of fine-resolution projections with appropriate uncertainty measures for better preparing region-specific adaptation plans.
Earth–directed coronal mass ejections and their geoeffectiveness during the 2007–2010 interval

Abstract In this study we analyse the coronal mass ejections (CMEs) directed towards the Earth during the interval 2007–2010, using the data acquired by STEREO mission and those provided by SOHO, ACE and geomagnetic stations. A study of CMEs kinematics is performed. This is correlated with CMEs interplanetary manifestations and their geomagnetic effects, along with the energy transfer flux into magnetosphere (the Akasofu coupling function). The chosen interval that is practically coincident with the last solar minimum, offered us a good opportunity to link and analyse the chain of phenomena from the Sun to the terrestrial magnetosphere in an attempt to better understand the solar and heliospheric processes that can cause major geomagnetic storms.
Effect of Perceived Usefulness and Perceived Ease of Use on University Students’ Willingness for online purchase

As an emerging form of consumption, online shopping has increasingly exerted more implications on the consumer market. This paper surveys a sample of SEGI university students, examining the implication of the perceived usefulness (PU) and perceived ease of use (PEU) on the college students’ willingness for online purchase. The results of the questionnaire were empirically analyzed by SPSS software. It shows that the PU can significantly and positively affects the willingness for online purchase of SEGI university students; and PEU can also significantly enhanced the willingness for online purchase of SEGI university students. Hence, this study not only enriches the theory of online consumption behavior, but also provides a scientific reference for online sellers to improve their service quality.
Association between Polyphenol Intake and Lipid Profile of Adults and Elders in a Northeastern Brazilian Capital

This research was aimed at evaluating the relationship between the estimated polyphenol intake and the atherogenic lipid profile in adult and elder residents in the city of Teresina, located in the Northeastern Region of Brazil. This study was a cross-sectional population-based survey with 501 adults and elders, conducted in Teresina, Brazil. Food intake was obtained by 24-h food recall. The estimated polyphenol intake was calculated by multiplying the food consumption data from the recall by the polyphenol content in the foods described in the Phenol-Explorer database. The mean intake of total polyphenols was 1006.53 mg/day. The phenolic acids was the class with the highest intake, followed by the flavonols. Coffee, beans and apples were the main foods contributing to the total polyphenol intake. In the individuals with elevated serum concentrations of total cholesterol and triglycerides, the intake of total polyphenols was significantly higher. The intake of total polyphenols, phenolic acids and lignans was higher in the subjects with dyslipidemia. This article provides, for the first time, data on the intake of the total polyphenol classes and subclasses in the evaluated population and the relationship with the lipid profile. The individuals with a higher intake of total polyphenols had a worse lipid profile, which may be a consequence of an improved diet in those individuals who present with dyslipidemia.
SILICON DEPLETION IN THE INTERSTELLAR MEDIUM

We report interstellar silicon (Si) depletion and dust-phase column densities of Si along 131 Galactic sight lines using archival observations. The data were corrected for differences in the assumed oscillator strength. This is a much larger sample than previous studies but confirms the majority of results, which state that the depletion of Si is correlated with the average density of hydrogen along the line of sight ( 〈 n ( H ) 〉 ) as well as the fraction of hydrogen in molecular form (f(H2)). We also find that the linear part of the extinction curve is independent of Si depletion. Si depletion is correlated with the bump strength (c3/RV) and the FUV curvature (c4/RV) suggesting that silicon plays a significant role in both the 2175 Å bump and the FUV rise.