Miracle-dz/UniFAR-FTUs huggingface dataset:
Isolated Tubercular Epididymitis: A 10-Year Series

Introduction: Genitourinary tuberculosis (TB) is considered a common form of extrapulmonary TB, being second only to lymph node tuberculosis, which is the most common site. Isolated TB of the epididymis is rare, and diagnosis of epididymal TB can be challenging. In this study, we report our series of isolated TB of the epididymis. Materials & Methods: We retrospectively collected the outpatient and inpatient records of histologically confirmed epididymal tuberculosis. Data including age, clinical presentation, examination findings, and diagnostic tests were reviewed and analyzed. Results: A total of 56 patients were diagnosed to have isolated tuberculosis of the epididymis during the 10-year study period. The mean age was 33 years. The clinical presentation included a hard nodule in the epididymis (100%), hydrocele in 16 (28.5%), posterior scrotal sinus in 6 (10.7%), and sensitivity in 14 (25%) and fever in 3 (5.3%). Four (7.1%) patients had bilateral epididymal nodules, 30 (53.5%) had left-sided, and 22 (39.2%) had right-sided involvement. Scrotal exploration and epididymal biopsy were performed in 16 (28.5%), and unilateral epididymectomy was performed in 40 (71.4%). The histopathological examination revealed a typical tubercular granuloma in all these patients. All patients were put on anti-TB drugs. Conclusions: Isolated TB of the epididymis is a rare disease. Treatment with anti-TB drugs remains the first-line intervention in all cases. Surgery is indicated in cases of failure of pharmacological treatment or the development of complications.
Mindfulness-based cognitive therapy improves insomnia symptoms in individuals with recurrent depression: secondary analyses from a randomized controlled trial

Background Embedded within a randomized efficacy trial, the present study aimed to investigate whether mindfulness-based cognitive therapy (MBCT) for recurrent depression improved symptoms of insomnia. Methods Sixty-eight remitted participants with at least three prior episodes of depression were randomized to 8 weeks of MBCT (n = 33) or a waitlist control condition (n = 35). The Bergen Insomnia Scale was used to screen for insomnia symptoms before and after the intervention. The analyses were conducted using one-way between-groups analyses of covariance. Results Twenty-five MBCT participants and 30 waitlist controls completed the study (74.5% females; mean age 40.7 ± 12.9 years). At baseline, 83.6% screened positive for the insomnia diagnosis. Following the intervention and after controlling for corresponding insomnia parameters at baseline, MBCT completers reported significantly less severe insomnia symptoms (p = 0.017), as well as less problems with prolonged sleep onset (p = 0.047) and nocturnal awakenings (p = 0.023), relative to controls. No group differences were found on early morning awakening, daytime impairment, or dissatisfaction with sleep. Conclusion The results suggest that MBCT improves certain insomnia symptoms. However, additional sleep-specific interventions may be needed to further improve this population’s sleep. Clinical Trial Registration: ISRCTN, ISRCTN18001392, registered 22/11/2018. URL: 10.1186/ISRCTN18001392.
ANALYSIS OF IMIS'S SUCCESS ON TEACHER PERFORMANCE AND ORGANIZATIONAL PERFORMANCE IN VOCATIONAL SCHOOLS

This paper aims to analyze the factors that influence individual and organizational performance regarding the use of an Internship Management Information System (IMIS), which is named the SIM-PKL application for the internship program at SMK Negeri 11 Malang, with a framework in the DeLone and McLean Information Systems Success Model (ISSM). A quantitative method was employed, gathering data from SIM-PKL users. The sample comprised 55 respondents: 9 coordinators, 30 vocational teachers, and 16 general subject teachers. The analysis identifies key success factors, including system quality, information quality, service quality, intention to use, satisfaction, individual performance, and organizational performance. The findings align with the Delone & McLean framework, which evaluates information system success. Further analysis revealed a significant direct influence of system quality, information quality, and service quality on usage intentions and user satisfaction, while the net benefits (individual and organizational performance) were not statistically significant. Intention to use and user satisfaction are able to significantly mediate the influence of system quality, information quality, and service quality on net benefits. Intention to use and user satisfaction are important to increase system usage, enhance productivity, and positively affect performance. This study contributes to understanding SIM-PKL to guide schools in enhancing their management information systems.
Fusion Length Requiring Spinopelvic Fixation in Lumbosacral Fusion with Anterior Column Support at L5–S1: Assessment of Fusion Status Using Computed Tomography

Background The lumbosacral (LS) junction has a higher nonunion rate than other lumbar segments, especially in long-level fusion. Nonunion at L5–S1 would result in low back pain, spinal imbalance, and poor surgical outcomes. Although anterior column support at L5–S1 has been recommended to prevent nonunion in long-level LS fusion, fusion length requiring additional spinopelvic fixation (SPF) in LS fusion with anterior column support at L5–S1 has not been evaluated thoroughly. This study aimed to determine the number of fused levels requiring SPF in LS fusion with anterior column support at L5–S1 by assessing the interbody fusion status using computed tomography (CT) depending on the fusion length. Methods Patients who underwent instrumented LS fusion with L5–S1 interbody fusion without additional augmentation and CT > 1 year postoperatively were included. The fusion rates were assessed based on the number of fused segments. Patients were divided into two groups depending on the L5–S1 interbody fusion status: those with union vs. those with nonunion. Binary logistic regression analyses were performed to identify risk factors for LS junctional nonunion. Results Fusion rates of L5–S1 interbody fusion were 94.9%, 90.3%, 80.0%, 50.0%, 52.6%, and 43.5% for fusion of 1, 2, 3, 4, 5, and ≥ 6 levels, respectively. The number of spinal levels fused ≥ 4 (p < 0.001), low preoperative bone mineral density (BMD; adjusted odds ratio [aOR], 0.667; p = 0.035), and postoperative pelvic incidence (PI) – lumbar lordosis (LL) mismatch (aOR, 1.034; p = 0.040) were identified as significant risk factors for nonunion of L5–S1 interbody fusion according to the multivariate logistic regression analysis. Conclusions Exhibiting ≥ 4 fused spinal levels, low preoperative BMD, and large postoperative PI–LL mismatch were identified as independent risk factors for nonunion of anterior column support at L5–S1 in LS fusion without additional fixation. Therefore, SPF should be considered in LS fusion extending to or above L2 to prevent LS junctional nonunion.
Using Denosumab as a Nonsurgical Management of Aneurysmal Bone Cysts in the Pelvis

Background Aneurysmal bone cysts (ABCs) are infrequent, benign, and locally destructive lesions that most commonly occur during the first two decades of life. They usually affect the metaphysis of the long bones, but the pelvis is involved in 8%–12% of the cases. The management of pelvic ABCs is a challenging issue due to difficulties in choosing the appropriate approach, adjacent neurovascular bundles, the risk of intraoperative bleeding with difficulty achieving good hemostasis, and the risk of injury to the hip or sacroiliac joints. Limited data exist concerning the use of denosumab as a non-surgical treatment for pelvic ABCs. Our hypothesis was that denosumab might be an effective and safe solo treatment of cases with ABCs in the pelvis. Methods We retrospectively assessed 20 patients with ABCs in the pelvis, who were treated by denosumab as a solo agent without surgery. Patients were assessed regarding disease control, the incidence of recurrence and non-oncological complications, and functional outcome. Results The mean follow-up period was 38.5 months. Disease control was achieved in 16 patients (80%), with no local recurrence. Tolerable drug-related complications occurred in 15% of cases. The mean Musculoskeletal Tumor Society score was 92.3%. Conclusions Denosumab may provide a reliable option in the nonsurgical treatment of ABCs of pelvic origin with expected lower morbidity than the surgical solution and tolerable complications. Further studies on the safety profile and long-term effects of denosumab especially in skeletally immature patients are required.
Linking national culture and entrepreneurship: a systematic literature review

PurposeThis study generates an aggregated overview of the literature on national culture and entrepreneurship (NC&E). The aim is to map the NC&E field via a systematic literature review of 130 articles published in refereed academic journals up to the end of 2022Design/methodology/approachTwo different citation analysis methods are used: bibliographic coupling and co-citationFindingsThe results include the most influential studies, top-cited references and journals, and five major thematic clusters. The latter are (1) cultural models, frameworks and case studies; (2) social entrepreneurship, perceived barriers and entrepreneurial intentions; (3) institutions and sociocultural environments; (4) entrepreneurial orientation, cognition and networks; and (5) economic growth, entrepreneurial activity and firm performanceOriginality/valueIn contrast to previous NC&E literature reviews, this research employs a combination of bibliographic coupling and co-citation analysis. The findings offer a clearer understanding of the intellectual structure of this field and suggest new avenues for future investigations, including several relationship links with the resource-based view
The impact of remuneration to performance in public university in Indonesia

The aim of this research is to explore the relationship between remuneration, job satisfaction, and employee performance. Remuneration, in this context, refer to a system synchronization that is based on performance appraisal result. In this, regard, the research employed a descriptive quantitative method, with a population comprising all University of Padjadjaran lecturers which were a total of 2,090. Furthermore, in order to gather the research sample, a probability sampling technique was employed. This technique was selected because of its reputation as the most general strategic sampling technique in quantitative research to achieve representativeness (1). The obtained result showed that there was a positive and significant relationship between the remuneration and job satisfaction of lecturers in University of Padjadjaran. Accordingly, a significant value of 0.000 < 0.05 and a t-count value of 19.330 > 1.95 was observed, meaning the H1 hypothesis in this research was accepted. It is also expedient to acknowledge that a positive and significant relationship was found between job satisfaction and the performance of the lecturers in study area. For this relationship, a significant value of 0.010 < 0.05 and a t-count value of 5.676 > 1.95 was found. These findings led to the acceptance of the H2 hypothesis proposed in this research. Similarly, the relationship between remuneration and the performance of the observed lecturers was found to be positive and significant. The observed significant value in this regard was 0.000 < 0.05 and the t-count value was 4.057 > 1.95, indicating that H3 hypothesis was also accepted. Lastly, the relationship between remuneration and employee performance mediated by job satisfaction of lecturer in University of Padjadjaran was explored, and it was found to also be positive and significant, with a significant value of 0.000 < 0.05 and a t-count value of 5.429 > 1.95. This indicated that the H4 hypothesis proposed in the research was accepted.
RICE DISEASE RECOGNITION USING TRANSFER LEARNING XCEPTION CONVOLUTIONAL NEURAL NETWORK

As one of the major rice producers, Indonesia faces significant challenges related to plant diseases such as blast, brown spot, tugro, leaf smut, and blight. These diseases threaten food security and result in economic losses, underscoring the importance of early detection and management of rice diseases. Convolutional Neural Network (CNN) has proven effective in detecting diseases in rice plants. Specifically, transfer learning with CNN, particularly the Xception model, has the advantage of efficiently extracting automatic features and performing well even with limited datasets. This study aims to develop the Xception model for rice disease recognition based on leaf images. Through the fine-tuning process, the Xception model achieved accuracies, precisions, recalls, and F1-scores of 0.89, 0.90, 0.89, and 0.89, respectively, on a dataset with a total of 320 images. Additionally, the Xception model outperformed VGG16, MobileNetV2, and EfficientNetV2.
Ultrasonic anisotropic P-wave attenuation of shales under elevated pressures

The mechanisms of ultrasonic attenuation in reservoir rock are known to be sensitive to multiple rock physical properties; this study focuses on ultrasonic experiments that measure the anisotropic attenuation in shales as function of hydrostatic confining pressure; four Eagleford and Bakken samples were measured using new experimental setup that allows measuring anisotropic acoustic properties of sample simultaneously with only one core plug. Our tests show that P-wave attenuation is sensitive to confining pressure, and attenuation anisotropy is stronger than velocity anisotropy, especially for more isotropic samples; the highly active change of attenuation with pressure supports the opinion that attenuation is a highly sensitive parameter to rock intrinsic properties. Moreover, attenuation as a function of pressure clearly suggests a two-phase attenuation mechanism exists in shale: high aspect ratio pores/microcracks closure and the related scattering attenuation on crack surfaces dominate attenuation behavior under low pressure, while at high pressure the main mechanism shifts to intrinsic attenuation caused by grain/crack friction and anelasiticity. The measured anisotropy data could be used for understanding the loss mechanisms responsible for seismic attenuation, and would benefit the development of theoretical attenuation rock physics models, as well as the interpretation of well logging and seismic surveys in shale reservoirs.
Production and characterization of single-chain variable fragment antibodies targeting the breast cancer tumor marker nectin-4

Background Nectin-4 is a novel biomarker overexpressed in various types of cancer, including breast cancer, in which it has been associated with poor prognosis. Current literature suggests that nectin-4 has a role in cancer progression and may have prognostic and therapeutic implications. The present study aims to produce nectin-4-specific single-chain variable fragment (scFv) antibodies and evaluate their applications in breast cancer cell lines and clinical specimens. Methods We generated recombinant nectin-4 ectodomain fragments as immunogens to immunize chickens and the chickens' immunoglobulin genes were amplified for construction of anti-nectin-4 scFv libraries using phage display. The binding capacities of the selected clones were evaluated with the recombinant nectin-4 fragments, breast cancer cell lines, and paraffin-embedded tissue sections using various laboratory approaches. The binding affinity and in silico docking profile were also characterized. Results We have selected two clones (S21 and L4) from the libraries with superior binding capacity. S21 yielded higher signals when used as the primry antibody for western blot analysis and flow cytometry, whereas clone L4 generated cleaner and stronger signals in immunofluorescence and immunohistochemistry staining. In addition, both scFvs could diminish attachment-free cell aggregation of nectin-4-positive breast cancer cells. As results from ELISA indicated that L4 bound more efficiently to fixed nectin-4 ectodomain, molecular docking analysis was further performed and demonstrated that L4 possesses multiple polar contacts with nectin-4 and diversity in interacting residues. Conclusion Overall, the nectin-4-specific scFvs could recognize nectin-4 expressed by breast cancer cells and have the merit of being further explored for potential diagnostic and therapeutic applications.
The role of supply chain management in improving performance of Jordanian small and medium enterprises

Supply chain management practices are always helpful for multinational enterprises in increasing their growth. However, there has always remained an open debate about which practices are helpful for small and medium enterprises (SMEs). Therefore, this study has examined the influence of supply chain management practices on the performance of SMEs. Moreover, it has examined how the moderation of supply chain ecocentricity and innovation capabilities strengthens or weakens the relationship between supply chain management practices and SMEs’ performance. The quantitative study involved 352 SME managers as they can provide the relevant information and possess complete knowledge of management practices. The data were gathered via a questionnaire, and the responses were analyzed using IBM SPSS 28 and IBM AMOS. The results show that SMEs’ performance is linked to supply chain management practices (β = 0.544; P &lt; .001), and this linkage is further strengthened by supply chain ecocentricity (R2 change = 0. 082***, F-Statistics = 47.18) and innovation capabilities (R2 change = 0.061***, F-Statistics = 39.74). SMEs can enhance their performance by efficiently incorporating supply chain management practices and developing innovation capabilities and supply chain ecocentricity. AcknowledgmentsThis study is funded by Al Hussein Bin Talal University, Ma’an, Jordan, No. 125/2023.
Real Exchange Rates and Sectoral Productivity in the Eurozone

We investigate the link between real exchange rates and sectoral TFP for eurozone countries. We show that real exchange rate variation, both cross-country and time-series, closely accords with an amended Balassa-Samuelson interpretation, incorporating sectoral productivity shocks and a labor market wedge. We construct a DSGE model to generate a cross section and time series of real exchange rates to compare to data. Estimates from simulated regressions are very similar to estimates for eurozone data. Our findings contrast with previous studies that have found little relationship between productivity and real exchange rates among high-income countries that have floating nominal exchange rates. (JEL E12, E23, E24, F31, F33, F43)
How Does Sustainable Organizational Support Affect Job Burnout in the Hospitality Sector? The Mediating Role of Psychological Capital

The hospitality industry is often regarded as a labor-intensive sector which is particularly susceptible to job burnout among employees, emphasizing its significant reliance on human resources for various service-oriented functions. This study explores the intricate dynamics between organizational support, job burnout, and psychological capital in the context of the hospitality sector. It aims to investigate how the level of support provided by organizations influences the occurrence of job burnout among employees in the hospitality industry, with a specific focus on the mediating role played by psychological capital. This research employs a theoretical framework to examine the relationships between these key variables and adopts structural equation modeling (SEM) to analyze the data. The study encompassed data from a total sample of 385 employees, with a gender distribution indicating that the majority (64.1%, N = 247) were male, while 35.9% (N = 138) were female. The main results showed that psychological capital was significantly enhanced by organizational support (β = 0.714, t-value = 45.211). On the other hand, it was found that psychological capital (β = −0.092, t-value = 2.176) and organizational support (β = −0.477, t-value = 11.674) had a substantial negative impact on job burnout. The finding of this study showed that psychological capital mediates the relationship between job burnout and organizational support to some extent (β = −0.066, t-value = 2.134). The findings are anticipated to shed light on effective strategies for organizations to mitigate job burnout by fostering positive psychological capital through supportive organizational practices, ultimately enhancing the well-being and performance of employees in the demanding and dynamic field of hospitality. By unraveling the interplay of organizational support, psychological capital, and job burnout, this study contributes valuable insights to academia, sustainable occupational health, and practitioners in the hospitality sector.
Visualizing Convergence Dynamics across Regions and States: h-Convergence

Researchers interested in studying whether convergence dynamics are in place among regions within the same country have adopted both statistical tools and empirical frameworks developed when studying convergence across different economies. We show that this approach is risky, because when an analysis is conducted at the regional level, the absolute and club convergence processes are more likely to co-exist than in the case of world economies. We propose an empirical approach where the two hypotheses are not taken as competing. Our procedure uncovers periods of convergence and periods of divergence for the three samples we studied: Italy observed at both the regional and provincial levels; EU regions; and world economies. We find a process of absolute convergence for Italian regions from 1951 to 1999, and that their convergence process ends in 1971 after a period which we define as clustering convergence. We also find a process of convergence across European regions from 1977 to 1993; that ends in 1985 in favor of a process of clustering and divergence. Finally, our procedure uncovers a process of absolute convergence from 1964 to 1975 and divergence from 1975 to 1999 in the case of world economies.
Marketing de relaciones: un análisis de su definición

espanolLa mayor dificultad para definir el Marketing de Relaciones radica principalmente en que el concepto denota un conjunto de actividades que varian segun el contexto. Por ello, hay autores como Dann y Dann que sostienen que, para definir y obtener una idea clara del Marketing de Relaciones, bastaria con recurrir a cuatro definiciones que se realizan sobre el termino y a cinco variables que se desarrollan sobre su proceso. En consecuencia, una investigacion como la que proponemos esta mas que justificada, marcandonos un unico objetivo, que es proporcionar unas caracteristicas que definan el Marketing de Relaciones. Para alcanzar a dicho objetivo, conviene, pues, empezar por analizar y revisar la literatura existente sobre dicho concepto EnglishThe greatest difficulty to define relationship marketing lies mainly in the concept denotes a set of activities that vary according to context. Therefore, some authors like Dann and Dann who argue that, to define and get a clear idea of relationship marketing, suffice to use four definitions that are made on the term and five variables that develop on their process. Accordingly, an investigation as performed is more than justified, marking us one goal, which is to provide features that define the relationship marketing. To reach this goal we will use a literature review.