Miracle-dz/UniFAR-FTUs huggingface dataset:
Integrating External Resources with a Task-Based Programming Model

Accessing external resources (e.g., loading input data, checkpointing snapshots, and out-of-core processing) can have a significant impact on the performance of supercomputer applications. However, no existing programming systems for high-performance computing directly manage and optimize these external accesses. As a result, users must explicitly manage external accesses alongside their computation at the application level, which can result in both correctness and performance issues. We address this limitation by introducing Iris, a task-based programming model with semantics for external resources. Iris allows applications to describe their access requirements to external resources and the relationship of those accesses to the computation. Iris incorporates external I/O into a deferred execution model, reschedules external I/O to overlap I/O with computation, and reduces external I/O when possible. We evaluate Iris on three microbenchmarks representative of important workloads in HPC and a full combustion simulation, S3D. We demonstrate that the Iris implementation of S3D reduces the external I/O overhead by up to 20×, compared to the Legion and the Fortran implementations.
Optimal Selection of the Average Capacitor Voltage for Variable-Speed Drives With Modular Multilevel Converters

Variable-speed drives have reduced voltage requirements when operating below the base speed. In a modular-multilevel-converter-based (M2C-based) motor drive, it is then possible to operate with reduced voltage in the submodule capacitors, than at the base speed. In this sense, a greater capacitor-voltage ripple can be accommodated, without exceeding the maximum peak-capacitor voltage. This paper presents an analytical investigation for the optimal selection of the average capacitor voltage for M2Cs, when the motor is operating with rated torque, below the base speed. This method does not require any power exchange between the converter arms, so it keeps the conduction losses at the minimum level. Additionally, the method decreases the switching losses, due to the decreased capacitor-voltage level. The overall ratings of the converter remain the same as in the base-speed operation. It is shown that this method can be applied at a speed range between the base speed and down to approximately one third of it, i.e., an operating range that covers the requirements for typical pump- and fan-type applications. The results obtained from the analytical investigation are experimentally verified on a down-scaled laboratory prototype M2C.
Steroid-resistant nephrotic syndrome with mutations in NPHS2 (podocin): report from a three-generation family

Genetic causes of steroid-resistant nephrotic syndrome are being increasingly recognized. Mutations in NPHS2, which encodes the glomerular protein podocin, account for up to 17% of sporadic and 40% of familial cases, where they display an autosomal-recessive pattern of inheritance. This report describes a non-consanguineous family with three generations of individuals who are either compound heterozygotes for mutations in NPHS2 or who have inherited a mutation and a non-neutral polymorphism (R229Q). As well as providing an aetiological explanation, identifying pathogenic mutations and considering genotype-phenotype correlations can provide prognostic information and lead to changes in genetic counselling and management.
First-Trimester Screening for Trisomy 21 with Adjustment for Biochemical Results of Previous Pregnancies

Objective: To investigate the effect of associations in serum free β-hCG and PAPP-A between successive pregnancies on the performance of screening for trisomy 21 at 11–13 weeks’ gestation. Methods: In 8,499 women with two consecutive pregnancies, including 49 women with fetal trisomy 21 in the second pregnancy, the correlation in serum free β-hCG multiples of the median (MoM) and PAPP-A MoM between pregnancies was determined, and the effects of correcting for the correlation on the performance of screening was estimated. Results: There were significant associations between pregnancies in free β-hCG MoM (r = 0.4435) and PAPP-A MoM (r = 0.4796). In screening by maternal age and biochemistry at a risk cutoff of 1 in 100, in the second pregnancies the false-positive rate was 35.5% for those with screen-positive results in the first pregnancy, and this was reduced to 17.1% after adjustment for the results of the first pregnancy. Similarly, in women with screen-negative results in the first pregnancy, adjustment for the results improved the detection rate in the second pregnancy from 66.7 to 81.2%. Conclusions: In screening for trisomy 21, adjustment for the biochemical findings in a previous pregnancy has major effects on individual patient-specific risks, increases the detection rate and reduces the false-positive rate.
Design and optimization of LC oscillators

Presents a method for optimizing and automating component and transistor sizing for CMOS LC oscillators. We observe that the performance measures can be formulated as posynomial functions of the design variables. As a result, the LC oscillator design problems can be posed as a geometric program, a special type of optimization problem for which very efficient global optimization methods have recently been developed. The synthesis method is therefore fast, and determines the globally optimal design; in particular, the final solution is completely independent of the starting point (which can even be infeasible), and infeasible specifications are unambiguously detected. We can rapidly compute globally optimal trade-off curves between competing objectives such as phase noise and power.
Polarimetric Parameters for Growing Stock Volume Estimation Using ALOS PALSAR L-Band Data over Siberian Forests

In order to assess the potentiality of ALOS L-band fully polarimetric radar data for forestry applications, we investigated a four-component decomposition method to characterize the polarization response of Siberian forest. The decomposition powers of surface scattering, double-bounce and volume scattering, derived with and without rotation of coherency matrix, were compared with Growing Stock Volume (GSV). To compensate for topographic effects an adaptive rotation of the coherency matrix was accomplished. After the rotation, the correlation between GSV and double-bounce increased significantly. Volume scattering remained same and the surface scattering power decreased slightly. The volume scattering power and double-bounce power increased as the GSV increased, whereas the surface scattering power decreased. In sparse forest, at unfrozen conditions the surface scattering was higher than volume scattering, while volume scattering was dominant in dense forest. The scenario was different at frozen conditions for dense forest where the surface scattering was higher than volume scattering. Moreover, a slight impact of tree species on polarimetric decomposition powers has been observed. Larch was differed from aspen, birch and pine by +2 dB surface scattering power and also by −1.5 dB and −1.2 dB volume scattering power and double-bounce scattering power respectively at unfrozen conditions.
Millimeter-Wave On-Wafer TRL Calibration Employing 3-D EM Simulation-Based Characteristic Impedance Extraction

In this paper, we propose a method based on 3-D electromagnetic simulations, for the characteristic impedance extraction of transmission lines employed in TRL calibration, focusing on lines integrated in silicon technologies. The accuracy achieved with TRL calibrations using the proposed characteristic impedance extraction is benchmarked versus conventional approaches, with an emphasis on aluminum pads structures operating in the (sub) millimeter-wave range. The proposed method proves to be insensitive to common sources of error (i.e., large pad capacitance and inductive pad-to-line transitions), which affect the accuracy of characteristic impedance extraction based on measurements, especially as the testing frequency increases. First, direct on-wafer TRL calibrations are performed on uniform CPWs (i.e., with no pads discontinuities) to demonstrate how the proposed method performs as good as the calibration comparison method and outperforms calibration transfer approaches. Finally, the method is applied to a nonuniform CPW-based calibration kit, demonstrating how the proposed method provides accurate results, improving the calibration quality that can be achieved using the calibration comparison method when inductive pad-to-line transitions are present.
Transparent acceleration of software packet forwarding using netmap

Software packet forwarding has been used for a long time in general purpose operating systems. While interesting for prototyping or on slow links, it is not considered a viable solution at very high packet rates, where various sources of overhead (particularly, the packet I/O mechanisms) get in the way of achieving good performance. Having recently developed a novel framework (called netmap) for packet I/O on general purpose operating systems, we have investigated how our work can improve the performance of software packet processing. The problem is of interest because software switches/routers are widely used, and they are becoming inadequate with the increasing use of 1.10 Gbit/s links. The two case studies (OpenvSwitch and Click userspace) that we report in this paper give very interesting answers and insights. First of all, accelerating the I/O layer has the potential for huge benefits: we improved the performance of OpenvSwitch from 780 Kpps to almost 3 Mpps, and that of Click userspace from 490 Kpps to 3.95 Mpps, by simply replacing the I/O library (libpcap) with our accelerated version. On the other hand, reaching these speedups was not purely mechanical. The original versions of the two systems had other limitations, partly hidden by the slow packet I/O library, which prevented or limited the exploitation of these speed gains. In the paper we make the following contributions: i) present an accelerated version of libpcap which gives significant speedups for many existing packet processing applications; ii) show how we modified two representative applications (in particular, Click userspace), achieving huge performance improvements; iii) prove that existing software packet processing systems can be made adequate for high speed links, provided we are careful in removing other bottlenecks not related to packet I/O1.
Enhancing ZF-SIC by Selective Retransmissions: On Algorithms for Determining the Decoding Order

We consider the uplink of a wireless sensor network with single-antenna sensors, an access point (AP) equipped with multiple antennas, and a common radio channel. To reduce the number of outages resulting from the noise amplification by the zero-forcing (ZF) within the successive interference cancellation (SIC) procedure, the AP is given the possibility to request a selected number of sensors to retransmit their signals in a subsequent time slot. If necessary the AP suspends the ZF-SIC until the requested signals have been retransmitted, making the signal recovery a recursive procedure. The number of sensors required to retransmit depends on the order of the processed sensor signals within the ZF-SIC. We propose two algorithms for determining the decoding order: an algorithm which finds a decoding order necessitating a minimal number of retransmissions, and a suboptimal alternative algorithm with significantly lower complexity. By numerical means the performance and complexities of the considered algorithms are analyzed.
Role of T cell subsets in lethal graft-versus-host disease (GVHD) directed to class I versus class II H-2 differences. I. L3T4+ cells can either augment or retard GVHD elicited by Lyt-2+ cells in class I different hosts

Detailed information was sought on the capacity of purified Lyt-2+ cells to mediate lethal graft-versus-host disease (GVHD) directed to class I H-2 differences. When B6 Lyt-2+ cells were transferred to irradiated class I-different (B6 x bm 1)F1 mice, three different patterns of lethal GVHD were observed. First, rapid death from hematopoietic failure occurred when Lyt-2+ cells were transferred together with host-type marrow cells; this form of GVHD probably reflected direct destruction of stem cells by Lyt-2+ cytotoxic cells. Second, a pattern of late-onset, chronic GVHD resulting in death only after 4-6 wk occurred when Lyt-2+ cells were supplemented with donor marrow. This syndrome developed in the apparent absence of L3T4+ cells and was observed with either high or low doses of Lyt-2+ cells and with either light or heavy irradiation of the host. Third, an acute form of GVHD resulted when Lyt-2+ cells plus donor marrow cells were supplemented with exogenous help, i.e., by adding small doses of donor L3T4+ cells or injecting the hosts with rIL-2. Although L3T4+ cells potentiated GVHD when injected in small doses, supplementing Lyt-2+ cells with large doses of L3T4+ cells paradoxically led to marked protection; symptoms of GVHD were mild and no deaths occurred.
Markov Decision Processes with Arbitrary Reward Processes

We consider a learning problem where the decision maker interacts with a standard Markov decision process, with the exception that the reward functions vary arbitrarily over time. We show that, against every possible realization of the reward process, the agent can perform as well---in hindsight---as every stationary policy. This generalizes the classical no-regret result for repeated games. Specifically, we present an efficient online algorithm---in the spirit of reinforcement learning---that ensures that the agent's average performance loss vanishes over time, provided that the environment is oblivious to the agent's actions. Moreover, it is possible to modify the basic algorithm to cope with instances where reward observations are limited to the agent's trajectory. We present further modifications that reduce the computational cost by using function approximation and that track the optimal policy through infrequent changes.
Experimental Determination of Cover Surface Temperature Functions at MSW Landfills

Cover temperatures were measured at four MSW landfills located in different climatic regions in North America: Michigan, New Mexico, Alaska, and British Columbia. Temperature measurements were made on a weekly basis throughout the depth of the cover profiles extending from the surface into the top layers of the underlying wastes. Bias was produced in the surface temperature data due to the combined effects of the time of day that weekly surface measurements were taken and the high diurnal variations at the surface. Analytical methods were used to obtain representative surface temperature functions for the covers from experimental data. Mean cover surface temperatures were estimated by extrapolating near-surface temperatures using exponential functions and by interpolating between air and below- surface cover temperatures using weighting factors. Surface temperature amplitudes were estimated by extrapolating near-surface amplitudes using conventional earth temperature theory. Analysis of data indicated that mean cover surface temperatures and cover temperature amplitudes can also be obtained directly from temperature measurements at 150 to 300 mm depth, when such data are available. Surface parameters obtained in this study can be used at other sites with similar climatic conditions for thermal analysis of cover systems.
Bilingual children with language impairment: A comparison with monolinguals and second language learners

ABSTRACT The purpose of this study is twofold: (a) to examine whether English finite morphology has the potential to differentiate children with and without language impairment (LI) from Spanish-speaking backgrounds and different levels of English proficiency in comparison to Hispanic English speakers and (b) to investigate the extent to which children who are bilingual exhibit differences in their grammatical performance because of cross-linguistic influence from their first language. Seventy-one children between the ages of 4 years, 5 months and 6 years, 5 months were distributed into the following five groups: English as a first language (EL1) speakers with typical language development (TLD), EL1 speakers with LI, Spanish–English bilinguals with TLD, Spanish–English bilinguals with LI, and English as a second language (EL2) learners with TLD were compared on regular verb finiteness and nominative subject use using spontaneous narrative samples. The EL1 children with LI had significantly lower verb accuracy rates than the EL1 controls with TLD. Verb finiteness marking was also a significant discriminator for the bilinguals with LI. There was no evidence of cross-linguistic influence, however. The analysis indicated no significant differences between EL1 and bilingual children on subject or verb use. The EL2 group only presented difficulties with finite verb use. The typological differences between English and Spanish for overt subject use did not seem to affect the performance of either typical or atypical bilingual learners. The findings underscore the need for addressing language dominance in future bilingual studies.
Diffusion of aminoglycoside antibiotics across the outer membrane of Escherichia coli

The diffusion of aminoglycoside antibiotics (gentamicin, kanamycin, streptomycin, fradiomycin, lividomycin, and mannosylparomomycin) through porin pores was examined in vitro by the liposome swelling technique, using vesicle membranes reconstituted from phospholipids and purified porin trimers. Results showed that aminoglycoside antibiotics diffuse through porin-pores very efficiently, as rapidly as hexoses and disaccharides, despite the fact that the molecular weights of the aminoglycosides used were higher than or close to the exclusion limit of porin pores. The susceptibility to aminoglycoside antibiotics of mutant strains producing 3 to 4% of porin was not significantly different from that of a strain producing a wild-type quantity of porin. These results were interpreted to mean that aminoglycoside antibiotics diffuse through porin-pores very efficiently. Therefore, the diffusion of these drugs through the mutant outer membranes producing 3 to 4% of porin is not a rate-limiting step for aminoglycoside diffusion and its action.
The effects of intonation on infant attention: the role of the rising intonation contour

ABSTRACT The study was designed to investigate 2-month-old infant preferential attention to a feature found to be characteristic of mothers' speech to their infants. A modified infant-control auditory preference paradigm was employed to assess infants' differential attention to synthetically generated and naturally produced rising and falling intonation contours. Analysis of these data revealed that the infants attended more to the rising naturally produced intonation contour. A reverse pattern of greater attention to the falling contour was found with the synthetically generated stimuli. In addition, inspection of the results permitted the conclusion that the infant-control preference paradigm was a viable method for assessing the 2-month-old infant's preferential attention to auditory stimuli. The results are discussed in terms of their relevance to the study of the infant's developing language reception abilities.
Altering Trehalose-6-Phosphate Content in Transgenic Potato Tubers Affects Tuber Growth and Alters Responsiveness to Hormones during Sprouting1[C][W]

Trehalose-6-phosphate (T6P) is a signaling metabolite that regulates carbon metabolism, developmental processes, and growth in plants. In Arabidopsis (Arabidopsis thaliana), T6P signaling is, at least in part, mediated through inhibition of the SNF1-related protein kinase SnRK1. To investigate the role of T6P signaling in a heterotrophic, starch-accumulating storage organ, transgenic potato (Solanum tuberosum) plants with altered T6P levels specifically in their tubers were generated. Transgenic lines with elevated T6P levels (B33-TPS, expressing Escherichia coli osmoregulatory trehalose synthesis A [OtsA], which encodes a T6P synthase) displayed reduced starch content, decreased ATP contents, and increased respiration rate diagnostic for high metabolic activity. On the other hand, lines with significantly reduced T6P (B33-TPP, expressing E. coli OtsB, which encodes a T6P phosphatase) showed accumulation of soluble carbohydrates, hexose phosphates, and ATP, no change in starch when calculated on a fresh weight basis, and a strongly reduced tuber yield. [14C]Glucose feeding to transgenic tubers indicated that carbon partitioning between starch and soluble carbohydrates was not altered. Transcriptional profiling of B33-TPP tubers revealed that target genes of SnRK1 were strongly up-regulated and that T6P inhibited potato tuber SnRK1 activity in vitro. Among the SnRK1 target genes in B33-TPP tubers, those involved in the promotion of cell proliferation and growth were down-regulated, while an inhibitor of cell cycle progression was up-regulated. T6P-accumulating tubers were strongly delayed in sprouting, while those with reduced T6P sprouted earlier than the wild type. Early sprouting of B33-TPP tubers correlated with a reduced abscisic acid content. Collectively, our data indicate that T6P plays an important role for potato tuber growth.
A FULL GIS-BASED WORKFLOW FOR TREE IDENTIFICATION AND TREE CROWN DELINEATION USING LASER SCANNING

Laser scanning or LiDAR data are increasingly used in forestry applications but also e.g. in urban environments or for building reconstructions. Huge point clouds are usually converted to a grid or are pre-processed in specific software packages. In this paper we present a methodology to extract and delineate single trees from small footprint, high intensity laser scanning point data in a GIS environment. Additional image data are only used for visualisation purposes and for accuracy assessment. The objective was to demonstrate the potential of a fully GIS-based workflow. After various pre-processing steps within the GIS, we developed a local maxima algorithm to identify tree tops. Secondly, we developed a region growing algorithm to delineating the respective tree crowns. It utilizes the original laser point data and not a derived raster data set such as a DSM. The algorithm was tested for six test plots located within the National Park Bavarian Forest (Germany) which is considered a natural or near-natural forest. For these plots, the results of extensive field surveys were available. Dominant trees could be detected with an accuracy of 72.2% but the overall tree detection rate was 51%. Suboptimal scan sampling distribution hinders perfect tree crown delineation. Our main goal to develop and demonstrate a complete GIS-based workflow from Laser data pre-processing, algorithm development, analysis, to visualisation etc. – was reached. However, locating and counting trees within the LiDAR point cloud, particularly in multi-tiered deciduous plots and juvenile stands, requires the assistance of field-validation data and some subjective interpretation.
A Privacy Enhanced Security Framework for Android Users

In the past few years, the primary focus of computing has shifted from PCs to smart-phones and tablets. As a result, smart-phones have become more than a communication device, now it can store vast amount of user's sensitive data. Further, its popularity also opens a new era of application development; because of which Google's Play Store now contains millions of free Android applications. To use these applications users are bound to give the permission to access their data as a cost of the application. The required permissions, sometimes are genuine (such as location information required by Google map, etc), however in most of the cases they need unnecessary permissions due to which security and the privacy of user are hampered. Considering these facts, in this paper, we proposed a computationally efficient framework to enhance the privacy as well as the security of Android users.