Miracle-dz/UniFAR-FTUs huggingface dataset:
Downlink SINR distribution in a heterogeneous cellular wireless network with biased cell association

For an arbitrarily-located user terminal (UE) in a multi-tier heterogeneous cellular wireless network, the joint distribution of the downlink SINR at the UE from the candidate serving base stations (BSs) in the accessible tiers of the network has been derived in closed form for the cases where the candidate serving BS from each accessible tier is chosen as either the one nearest to the UE [1] or the one that is received strongest (equivalently, with maximum SINR) at the UE [2], when the locations of the BSs in the tiers are modeled by independent Poisson Point Processes, and the fading on all links is assumed independent identically distributed (iid) and Rayleigh. The actual serving BS for the UE is chosen as the nearest/strongest/max-SINR candidate serving BS after imposing selection bias across the tiers. The above joint distributions can be used to yield the distribution of the actual SINR at the UE (i.e., when receiving from this serving BS) when no selection bias exists across tiers. However, for the practically important case of selection bias, analytical calculation of the distribution of the actual SINR presents significant challenges. This work derives and summarizes the distribution of actual downlink SINR for all the above criteria for selection of the serving BS accounting for selection bias. We then explore some implications of these results for design and operation of a heterogeneous network.
Advances in Brief Significantly High Levels of Ultraviolet-specific Mutations in the Smoothened Gene in Basal Cell Carcinomas from DNA Repair-deficient Xeroderma Pigmentosum Patients 1

The Sonic hedgehog (SHH) pathway is implicated in the etiology of the most common human cancer in Caucasians, the basal cell carcinoma (BCC). Mutations in the receptor of SHH, the patched gene, have been characterized in sporadic BCCs as well as those from patients with the rare genetic syndromes nevoid BCC and xeroderma pigmentosum (XP). To elucidate the role of UV in the deregulation of the SHH pathway, we analyzed for alterations of smoothened, a transmembrane signaling component regulated by patched, in BCCs and squamous cell carcinomas from UV hypersensitive XP patients. We find UV-specific smoothened mutations in 30% of XP BCCs, three times higher than those in sporadic Caucasian BCCs, confirming the high rate of UV-induced mutations in DNA repair-deficient XP patients. No alteration was found in XP squamous cell carcinomas, indicating the involvement of smoothened specifically in the development of BCC.
Circuit-Performance Implications for Double-Gate MOSFET Scaling below 25 nm

Circuit-performance implications for double-gate MOSFET scaling in the sub-25 nm gate length regime are investigated. The optimal gate-to-source/drain overlap needed to maximize drive current is found to be different than that needed to minimize FO-4 inverter delay due to parasitic capacitances. It is concluded that the effective channel length must be slightly larger than the physical gate length in order to achieve optimal circuit performance.
Coronary heart disease Relationship between circulating endothelial cells and the predicted risk of cardiovascular events in acute coronary syndromes

Aims The quantification of circulating endothelial cells (CECs) in whole blood is a novel marker of direct endothelial injury and shows promise as a potential biomarker of cardiovascular (CV) risk. The interrelationship(s) between CECs and predicted CV risk has not been explored in large cohort of ‘highrisk’ patients. We hypothesized that there would be a significant relationship between increasing CEC counts and predicted CV risk in a broad spectrum of patients presenting with acute coronary syndrome (ACS). Methods and resultsWe studied 197 patients (aged 40–80 years) admitted with a confirmed diagnosis of unstable angina (UA), non-ST-elevation myocardial infarction (MI, NSTEMI), or ST-elevation MI (STEMI). CEC counts were performed on venous whole blood using the immunobead technique. Four well-validated ACS risk scores [(PURSUIT and TIMI for NSTEMI/UA) TIMI (STEMI) and GRACE (all ACS)] were calculated from the initial clinical history and electrocardiogram, as well as from values of laboratory parameters collected within 12 h of admission. We included a healthy control (HC) group of 50 matched patients in order to quantify the accuracy of CEC counts for the diagnosis of ACS and to compare disease vs. HC counts. CEC counts were significantly higher in the disease group when compared with the HC group. CEC counts significantly increased with increasing severity of disease (that is, UA vs. NSTEMI vs. STEMI; P 1⁄4 0.002). CEC counts were higher among patients with clinical evidence of heart failure (Killip Class II–IV) when compared with those without (Killip Class I) on admission (P , 0.0001). There was a significant correlation between CEC counts and predicted CV risk for each of the four ACS risk scoring schemes (all P, 0.05). The area under the receiver-operating characteristic (ROC) curve (AUC) for the entire ACS cohort was 0.82 (95% CI: 0.76–0.88; P, 0.0001). A CEC count of 7/mL provided a positive predictive value of 90.6% (95% CI: 85.6–95.7%) and a negative predictive value of 53.5% (41.9–65.1%) for the diagnosis of MI (NSTEMI/STEMI) in the presence of an appropriate clinical presentation. Conclusion There is a significant and positive correlation between increasing CECs and increasing CV risk in ACS. The diagnostic accuracy of CECs in this setting is only ‘moderate’. Whilst it is good at confirming the presence of MI, a CEC value of ,7.0/mL is less reliable at confidently excluding patients without disease.
Agitation in Patients with Dementia - Challenges in Diagnosis and Treatment

Bakgrunn Forekomst av demens oker med alderen. Demens er et alvorlig helseproblem og den hyppigste arsaken til innleggelse pa sykehjem. Omtrent 30 til 50% av alle som far en demenssykdom utvikler en eller annen form av uro (agitasjon) i sitt sykdomsforlop. Dette bidrar til redusert livskvalitet hos pasientene, parorende og helsepersonell som har omsorg for dem. Det kan bli til en stor belastning for parorende og pleiepersonell og en diagnostisk, terapeutisk og okonomisk utfordring. Vi trenger psykofarmakologiske og ikke-farmakologiske behandlingsalternativer til de eksisterende medikamentene, fordi de har begrenset effekt, tales darlig og kan fore til alvorlige bivirkninger. Det er behov for gyldige verktoy som maler agitasjon for a kunne bedre evaluere pasientene for behandling og folge dem opp under behandling, ikke bare i klinisk praksis men ogsa i forskningssammenheng. De daglige rutinene pa sykehjem med sine mange konkurrerende krav forer til at kortversjoner av slike instrumenter foretrekkes. Formal Avhandlingen har tre formal: 1) Evaluere effekten av okskarbazepin (OXC) i behandling av alvorlig agitasjon og aggresjon hos pasienter pa sykehjem med Alzheimers sykdom eller vaskulaer demens eller en blandingsform av begge. 2) Studere de psykometriske egenskapene av den norske versjonen av Brief Agitation Rating Scale (BARS): Vi testet paliteligheten / repeterbarheten (reliabiliteten) og gyldigheten (validiteten) i et utvalg av norske sykehjemspasienter og gjennomforte en faktoranalyse av BARS it et annet utvalg. 3) Teste reliabilteten og validiteten av den norske versjonen av Neuropsychiatric Inventory, Nursing-home Version (NPI-NH). Metoder Ad 1) Vi gjennomforte en dobbelblind, placebokontrollert multisenterstudie uavhengig av farmakologisk industri ved a randomisere 103 pasienter i 35 sykehjem enten til placebo eller OXC. Forandringen i agitasjons- og aggresjonsskarene pa NPI-NH var det primaere endepunktet. De sekundaere endepunktene var forandringen pa pleiernes total belastning malt med NPI-NH og forandringen i sum skaren av BARS. Ad 2) BARS er en kortversjon av Cohen-Mansfield Agitation Inventory (CMAI) som maler agitasjon ved demens. Vi undersokte test-retest reliabiliteten og den indre konsistensen hos 56 sykehjemspasienter. Validitetsundersokelsen utforte vi hos 138 pasienter. I validitetsundersokelsen sammenliknet vi BARS skarene med NPI sub skala agitasjon/aggresjon og med Cornell Scale for Depression in Dementia: sub skala agitasjon. Dataene som vi brukte for a gjennomfore en faktoranalyse kom fra en studie som undersokte bruken av tvang og overvakning i norske sykehjem og som ble publisert av Oyvind Kirkevold et al. (2004). 1,870 sykehjemspasienter ble inkludert i analysen. Ad 3) De psykometriske egenskapene av NPI-NH ble testet. Vi undersokte inter-rater reliabiliteten mellom fagpersoner med forskjellige nivaer av helseutdannelse. Til dette formalet brukte vi kappa-statistikk. Femti pasienter ble inkludert og undersokt av en lege som ogsa skaret pasientenes atferd med BEHAVE-AD- og depresjonen…
Unusual DNA Structures Associated With Germline Genetic Activity in Caenorhabditis elegans

We describe a surprising long-range periodicity that underlies a substantial fraction of C. elegans genomic sequence. Extended segments (up to several hundred nucleotides) of the C. elegans genome show a strong bias toward occurrence of AA/TT dinucleotides along one face of the helix while little or no such constraint is evident on the opposite helical face. Segments with this characteristic periodicity are highly overrepresented in intron sequences and are associated with a large fraction of genes with known germline expression in C. elegans. In addition to altering the path and flexibility of DNA in vitro, sequences of this character have been shown by others to constrain DNA∷nucleosome interactions, potentially producing a structure that could resist the assembly of highly ordered (phased) nucleosome arrays that have been proposed as a precursor to heterochromatin. We propose a number of ways that the periodic occurrence of An/Tn clusters could reflect evolution and function of genes that express in the germ cell lineage of C. elegans.
Cache utilization for enhancing analyzation of Big-Data & increasing the performance of Hadoop

Our world generating a lot of different kinds of data. These data can be analyzed and processed for valuable information. The traditional systems like data base, which has been used to store and process, are failing to handle these huge data which ranges in tera and peta bytes and also known as Big-data. We have many tools which can be used to analyze Big-Data. The apache's hadoop is one of the most used Big-data analyzing frameworks, Hadoop uses large number of libraries to handle and manage Big-data processes. It also handles different kinds of failures which may occur in the system. It uses map-reduce programing paradigm to analyze, distributed processing and storage of Big-Data. Big-data will be divided in different blocks and distributed within the network. The mapper functions runs in parallel on each block of Big-data and parse it to filter out the required data, which can be used for further processing. The reducer function accepts the data from mapper functions and processes it for required or expected results. It has been observed that, the intermediate data generated by mapper while processing on same Big-Data is always same. Hence, system doing redundant operations and generates same results, which is not an efficient use of resources and it delays the performance speed of the system. The proposed system creates a novel cache, which stores the intermediate data or mapper's output into a novel cache. Whenever the system needs to analyze same Big-data set, It fetches already processed data from novel cache rather than running mapper function on whole Big-data set again.
Chaotic and variational calculus in discrete and continuous time for the poisson process

We study a new interpretation of the Poisson space as a triplet (H,B,P) where if is a Hilbert spaceB is the completion of H and P is the extension to the Borel σ-algebra of B of a cylindrical measure on B. A discrete chaotic decomposition of L 2(B P) is defined, along with multiple stochastic integrals of elements of H on. It turns out that the directional derivative of functionals in L 2(B P) in the direction of an element of H is an annihilation operator on the discrete chaotic decomposition. By composition with the Poisson process, we deduce continuous-time operators of derivation and divergence that form the number operator on the discrete chaotic decomposition. Those results are applied to the representation of random variables in the Wiener-Poisson chaotic decomposition
SER analysis of cooperative satellite-terrestrial network over non identical fading channels

In this study, the Symbol error rate (SER) performance of cooperative based downlink satellite system with single terrestrial relay is investigated by using amplify-and-forward cooperation protocol over non identical fading channels. A closed form expression of exact SER over non identical fading channels is derived for M-ary phase shift keying (M-PSK) and M-ary quadrature amplitude modulation (QAM). We have derived an expression of joint probability density function (PDF) of the relay channels which is used to obtain the SER expression. Statistical results of Land Mobile Satellite Channel (LMSC) are applied through numerical analysis to obtain the SER of the proposed system. It is shown that high cooperation gain is achieved at high SNR.
Effectiveness of Grasp Attributes and Motion-Constraints for Fine-Grained Recognition of Object Manipulation Actions

In this work, we consider the problem of recognition of object manipulation actions. This is a challenging task for real everyday actions, as the same object can be grasped and moved in different ways depending on its functions and geometric constraints of the task. We propose to leverage grasp and motion-constraints information, using a suitable representation, to recognize and understand action intention with different objects. We also provide an extensive experimental evaluation on the recent Yale Human Grasping dataset consisting of large set of 455 manipulation actions. The evaluation involves a) Different contemporary multi-class classifiers, and binary classifiers with one-vsone multi-class voting scheme, and b) Differential comparisons results based on subsets of attributes involving information of grasp and motion-constraints. Our results clearly demonstrate the usefulness of grasp characteristics and motion-constraints, to understand actions intended with an object.
The Devil is in the Framing: Analyzing Framing Strategies and Frame-Differences During the Pillar of Defense

In this study the differences in framing between the news media and the political public relations during a political conflict – the “Pillar of Defense” – were analyzed by applying the diagnostic, prognostic and mobilization framing tasks of Snow and Benford (1988). Also the use of moralization and justification, and their fit within this framework was examined. A deductive coding scheme was designed in order to perform a content analysis, drawing from newspapers from the United States, the Netherlands and Israel. In addition, the press releases and speeches by the main political leaders of Israel were analyzed. Besides the content analysis, statistical tests were conducted in SPSS to examine the correlations between the framework, justification and moralization. None of the correlations were statistically significant. The conclusion of the research is that the political Public Relations (PR) use the diagnostic and the mobilization frames more often than the news media do, however the news media use more prognostic frames than the political PR. Furthermore, the diagnostic frame uses the most justifications and the mobilization frames the most moralizations, compared to the total three framing tasks.
A Path Model of Workplace Solidarity, Satisfaction, Burnout, and Motivation

Communication dynamics within the business world dictate that the formality of interaction between supervisor and subordinate is determined by the supervisor. The present study investigates the influence of negotiated formality and closeness via supervisor-subordinate solidarity on subordinates’ burnout, motivation, and job satisfaction. An online questionnaire was administered to subjects across various occupations and organizations in the United States. The data are consistent with a mediated model in which job satisfaction mediates the relationships between solidarity-motivation and solidarity-burnout. These results are novel in that, first, job satisfaction is identified as an input of motivation and burnout rather than outputs of a shared induction, And, second, the results place renewed emphasis on the role of supervisor communication in the workplace as subordinates are unable to initiate solidarity.
REVIEW THE ALCOHOL HANGOVER-A PUZZLING PHENOMENON

The alcohol hangover develops when blood alcohol concentration (BAC) returns to zero and is characterized by a feeling of general misery that may last more than 24 h. It comprises a variety of symptoms including drowsiness, concentration problems, dry mouth, dizziness, gastro-intestinal complaints, sweating, nausea, hyper-excitability, and anxiety. The alcohol hangover is an intriguing issue since it is unknown why these symptoms are present after alcohol and its metabolites are eliminated from the body. Although numerous scientific papers cover the acute effects of alcohol consumption, researchers largely neglected the issue of alcohol hangover. This lack of scientific interest is remarkable, since almost everybody is familiar with the unpleasant hangover effects that may arise the day after an evening of excessive drinking, and with the ways these symptoms may affect performance of planned activities. Many people favour the (unproven) popular belief that dehydration is the main cause of alcohol hangover symptoms. However, taking a closer look at the present research on biological changes during alcohol hangovers suggests otherwise. A limited number of experiments have studied biological changes that are present the day after excessive drinking (for a review, see Ylikahri and Huttunen, 1977). Significant changes were reported on endocrine parameters (increased concentrations of vasopressin, aldosterone, and renin) and metabolic acidosis (reduced blood pH values due to increased concentrations of lactate, ketone bodies, and free fatty acids). These effects are related to dehydration and cause symptoms such as dry mouth and thirst. In addition, changes in immune system parameters (increased concentrations of pro-inflammatory cytokine [IL-12] and interferon-gamma [IFNγ]) have been reported (Kim et al ., 2003). It is likely that these changes in immune system parameters cause the more ‘cognitive’ alcohol hangover effects such as memory impairment and mood changes. Moreover, these findings suggest that alcohol hangover and dehydration are two independent yet co-occurring processes that have different underlying mechanisms. The idea that alcohol hangover symptoms (i.e. memory impairment) are related to immune system activation is strengthened by a relatively new discovery that the immune system and central nervous system (CNS) operate in close communication with each other (Maier and Watkins, 1998; Maier, 2003). The first line of evidence for the hypothesis that effects of immune activity on the CNS may be the cause of alcohol hangover comes from studies showing that cytokines
Buton macaques (Macaca ochreata brunnescens): crops, conflict, and behavior on farms

One consequence of anthropogenic habitat alteration is that many nonhuman primates are forced into conflict interactions with humans and their livelihood activities, especially through crop raiding. These problems are particularly acute for the endemic and threatened Buton Island macaque (Macaca ochreata brunnescens), in southeast Sulawesi, Indonesia. Our study investigated the crop raiding behavior of this species over time. Foods eaten and the behavioral repertoire exhibited by macaques during crop raiding at and inside farm perimeters were observed over a period of 8 years (2002–2009). Storage organ crops (e.g. sweet potato) were abundant and most frequently raided by macaques. Individual macaques were most commonly observed to raid close (0–10 m) to farm perimeters. Activities such as feeding, resting, moving, and social interaction varied significantly as a function of penetration distance into the farm, but only marginally between age‐sex classes. The annual average raid frequency per farm decreased over the latter years of the study period, raising questions about changes in macaque foraging and ranging behavior over time and their response to farm management and mitigation strategies. Am. J. Primatol. 74:29–36, 2012. © 2011 Wiley Periodicals, Inc.
Orientation culturelle et profession médicale. La relation thérapeutique dans les unités de rein artificiel et son environnement

Olgierd Kuty : Kulturelle Orientierung und Arztberuf . Die therapeutische Beziehung und ihre Umgebung in den Stationen fur Nierenbehandlung durch Kunstnieren. ; Der Verfasser untersucht die unabhangigen Variabeln, die den von ihm herausgestellten Strukturen zugrundeliegen in vier Kunstnierenstationen, zwei belgischen und zwei franzosischen. Zwei typische Strukturen zeichnen sich durch drei charakteristische Zuge aus : die mehr oder weniger grosse Vereinheitlichung des Krankenstatus, die Differenzierung bzw. die Ueberschneidung der Rollen des Krankenhausespersonals und der Kranken, und schliesslich die Art der Beziehung mit der Familie. Es wird festgestellt, dass die Technologie nicht die Ursache dieser Unterschiede ist, wie die technologischen Hypothesen von Perrow und Freidson glauben machen konnten, die der Verfasser zunachst bespricht. Somit wendet sich der Autor der Berufskultur zu und stellt zwei Orientierungstypen heraus, d.h. zwei Interaktionsstile, die die Beziehung kennzeichnet zwischen Arzt und Kranken einerseits und unter den Aerzten andererseits. Die kollegialbeziehung (= Beziehung unter Kollegen) spielt ofienbar eine vorrangige Rolle in der Strukturierung der therapeutischen Beziehungen. Das Orientierungskonzept, das sich hauptsachlich auf den Abhangigkeitsgrad und Unabhangigkeitsgrad stutzt, wie ihn die Beziehung entweder therapeutisch, oder kollegial, herbeifuhrt, ist somit auf eine Theorie der Macht innerhalb der menschlichen Beziehungen aufgebaut.
Design Concepts, Fabrication and Advanced Characterization Methods of Innovative Piezoelectric Sensors Based on ZnO Nanowires

Micro- and nano-scale materials and systems based on zinc oxide are expected to explode in their applications in the electronics and photonics, including nano-arrays of addressable optoelectronic devices and sensors, due to their outstanding properties, including semiconductivity and the presence of a direct bandgap, piezoelectricity, pyroelectricity and biocompatibility. Most applications are based on the cooperative and average response of a large number of ZnO micro/nanostructures. However, in order to assess the quality of the materials and their performance, it is fundamental to characterize and then accurately model the specific electrical and piezoelectric properties of single ZnO structures. In this paper, we report on focused ion beam machined high aspect ratio nanowires and their mechanical and electrical (by means of conductive atomic force microscopy) characterization. Then, we investigate the suitability of new power-law design concepts to accurately model the relevant electrical and mechanical size-effects, whose existence has been emphasized in recent reviews.