Miracle-dz/UniFAR-FTUs huggingface dataset:
INFLUENCE PRECEIVED CUSTOMER VALUE AND CUSTOMER SATISFACTION AGAINST CUSTOMER LOYALITY (CASE STUDIES IN THE TOURISM INDUSTRY THREE STAR HOTEL IN JEPARA)

Marketing in the twenty-first century experienced remarkable changes, with the inclusion of progress in the field of global information technology through the internet media. In this era many products / services that are presented through the media, so that the consumer or customer before making a purchase will create a perceived value that customers (CPV) (Kotler, 2009: 134) about the product / service to be bought. The concept of value is one of the basic elements of the theory of marketing (American Marketing Association, 2006 in Albert Graf 2008). Identify and create customer value - understood as value for customers - regarded as an important prerequisite for the success of the company in the future. Creating a loyal customer is the core of every business, one of the things that affect customer loyalty is to create value (Kotler, 2009: 134), the only value that can be created company is the value derived from the customer, a value that is owned company now and the time will come. A business is successful if it managed to obtain, maintain and grow the customer. In addition, factors that affect customer loyalty (CL) is customer satisfaction (CS). This research applies the theory of Customer preceived value via internet before choosing and buying services and hospitality and customer satisfaction after enjoying the hospitality of customer loyalty services at the three star hotel in Jepara. The purpose of this study was to test the direct influence preceived Customer Value and Customer satisfaction to customer satisfaction on customers' three-star hotel in Jepara. Keywords: Customer preceived value, customer satisfaction, customer loyalty.
The pricing and impact of rights issues of equity in Australia

We investigate abnormal returns resulting from the announcement of a rights issue in Australia and are the first study outside the United States and the United Kingdom to examine the pricing of rights issues and the determinants of that pricing. Rights issues generate a significantly negative abnormal return and, on average, are priced at a discount. The determinants of the announcement effect are analysed using a two-stage approach controlling for the endogeneity of the price discount. We first estimate the predicted discount and then include it as an independent variable in the announcement effect regression. The discount is positively related to the offer size and negatively related to underwriter quality, supporting underwriter certification models. We also include variables that have not been tested in any market, such as shareholder concentration which is negatively related to the discount implying that firms with higher shareholder concentration do not offer a significant discount as their shareholders wish to maintain their percentage holding in the firm. Further, the abnormal returns have a negative relationship with the predicted price discount, and a positive relationship with the use of proceeds. Finally, announcements made by resource firms generate larger negative reactions than other issuers.
Renminbi Nominal Effective Exchange Rate for Third Market Competition: An Approach Based on Disaggregated Trade Data

When measuring the nominal effective exchange rate (NEER), three factors should be considered: direct import competition, direct export competition and third market competition. The traditional NEER methodology using aggregated export trade data underestimates the competition between countries producing homogeneous goods, so that the weight of the effective exchange rates is too reliant on trade scale. Based on 2002 6-digit items of the Harmonized Commodity Description and Coding System, this paper employs the competitive stress index to adjust the weighting system of the renminbi NEER for third market competition. In the new weighting system, European countries and some emerging economies have higher weights compared with some of the developed countries, including the USA, Japan and resources-dominated economies. This research will facilitate the understanding of changes in China’s export competitiveness.
Oligomeric rearrangement of tick-borne encephalitis virus envelope proteins induced by an acidic pH

The flavivirus envelope protein E undergoes irreversible conformational changes at a mildly acidic pH which are believed to be necessary for membrane fusion in endosomes. In this study we used a combination of chemical cross-linking and sedimentation analysis to show that the envelope proteins of the flavivirus tick-borne encephalitis virus also change their oligomeric structure when exposed to a mildly acidic environment. Under neutral or slightly alkaline conditions, protein E on the surface of native virions exists as a homodimer which can be isolated by solubilization with the nonionic detergent Triton X-100. Solubilization with the same detergent after pretreatment at an acidic pH, however, yielded homotrimers rather than homodimers, suggesting that exposure to an acidic pH had induced a simultaneous weakening of dimeric contacts and a strengthening of trimeric ones. The pH threshold for the dimer-to-trimer transition was found to be 6.5. Because the pH dependence of this transition parallels that of previously observed changes in the conformation and hydrophobicity of protein E and that of virus-induced membrane fusion, it appears likely that the mechanism of fusion with endosomal membranes involves a specific rearrangement of the proteins in the viral envelope. Immature virions in which protein E is associated with the uncleaved precursor (prM) of the membrane protein M did not undergo a low-pH-induced rearrangement. This is consistent with a protective role of protein prM for protein E during intracellular transport of immature virions through acidic compartments of the trans-Golgi network.
Willingness to pay for quality improvements: comparative statics and interpretation of contingent valuation results.

This paper extends variation function theory by examining the effects of changes in prices, quality, and income on willingness to pay for quality change. Comparative static effects are found for both on-site users and nonusers of the resource. These results are used to interpret contingent valuation empirical models. For example, the substitution and complementary relationships between trips to natural resource sites can be identified. This paper also suggests tests for comparison of contingent valuation with recreation demand models and other tests of validity.
Peptide Agonist Docking in the N-terminal Ectodomain of a Class II G Protein-coupled Receptor, the VPAC1 Receptor

The neuropeptide vasoactive intestinal peptide (VIP) strongly impacts on human pathophysiology and does so through interaction with class II G protein-coupled receptors named VIP pituitary adenylate cyclase-activating peptide (PACAP) receptors (VPACs). The molecular nature of VIP binding to receptors remains elusive. In this work, we have docked VIP in the human VPAC1 receptor by the following approach. (i) VIP probes containing photolabile residues in positions 6, 22, and 24 of VIP were used to photolabel the receptor. After receptor cleavage and Edman sequencing of labeled receptor fragments, it was shown that Phe6, Tyr22, and Asn24 of VIP are in contact with Asp107, Gly116, and Cys122 in the N-terminal ectodomain (N-ted) of the receptor, respectively. (ii) The structure of VIP was determined by NMR showing a central α helix, a disordered N-terminal His1-Phe6 segment and a 310 Ser25-Asn28 helix termination. (iii) A three-dimensional model of the N-ted of hVPAC1 was constructed by using the NMR structure of the N-ted of corticotropin-releasing factor receptor 2β as a template. As expected, the fold is identified as a short consensus repeat with two antiparallel β sheets and is stabilized by three disulfide bonds. (iv) Taking into account the constraints provided by photoaffinity, VIP was docked into the hVPAC1 receptor N-ted. The 6-28 fragment of VIP nicely lies in the N-ted C-terminal part, but the N terminus region of VIP is free for interacting with the receptor transmembrane region. The data provide a structural rationale to the proposed two-step activation mechanism of VPAC receptor and more generally of class II G protein-coupled receptors.
Linking human resource management and knowledge management via commitment: A review and research agenda

This paper contributes to the development of the knowledge management and human resource management literatures through developing the linkages between them. Increasingly it is being acknowledged that the success of knowledge management initiatives is fundamentally predicated on having workers who are prepared to share their knowledge. It is suggested that HRM concepts and frameworks could be utilized to improve our understanding of what shapes the willingness (or reluctance) of workers to share their knowledge. Specifically the paper considers how the motivation of workers to share their knowledge may be shaped by their level of organizational commitment. Guest and Conway’s model of the psychological contract is modified to link commitment with knowledge‐sharing attitudes and behaviours. Finally, it is suggested that, if commitment is linked to knowledge‐sharing attitudes, then the apparently low commitment levels reported by a number of surveys may mean this represents a key problem for knowledge management initiatives.
Short-Open Calibration Technique for Accurate LE-FDTD Simulation of MEM switches

This paper proposes an accurate analysis of Microelectromechnanical (MEM) switches using the Lumped Element-Finite Difference Time Domain (LE-FDTD) method enriched of the Short-Open Calibration (SOC) technique. The application of this method allows the electrical behavior of MEM switches to be accurately predicted while reducing the computational CPU time.
Interaction of synapsin I with actin and SSVs: differential regulation by calmodulin.

The synapsin family of proteins has been implicated in the formation and retention of synapses. The four mammalian synapsins (I4 polypeptide chain size 74 kDa; Ib, 70 kDa; IIa, 63 kDa; and IIb, 52 kDa) are derived from two genes (I and I), the a and b isoforms being formed by differential mRNA splicing (Sudhof, 1989). These abundant proteins are peripheral to the membranes of small synaptic vesicles (SSV) and are major targets for multiple protein kinases (including cAMPdependent kinase and Calmodulin-dependent bases I and n). Studies on transgenic mice carrying null mutations in one or both of the synapsin genes ( R d et al., 1993, Rosahl et al., 1995) have suggested that synapsins are required for normal synaptic organisation and function. Recently, the synapsins in Drosophila have been molecularly cloned (Klagges et al., 1996). The synapsins cross-link SSVs to the cytoskeletal elements at presynaptic terminals, forming a ‘reserve’ pool of vesicles. Previous studies have demonstrated that these interactions are regulated by activation of calmodulin-depdent protein kinases (Bahler & Greengard, 1987, Petrucci & Morrow, 1987, Valtorta et al., 1992) and direct calmoddin binding (Goold et al., 1995): t h w regulatory motifs depress the activities of synapsins, leadmg to breaking of the vesiclecytoskeleton bridges, and release of SSV for exocytosis. Here we use an optical biosensor to show that synapsin I directly binds calmodulin (figure 1). This calciumdependent interaction is of high afiinity (19nM) and is typified by a relatively rapid association hase. No binding was observed in the absence of Ca’. We also show that calmodulin selectively regulates the interaction of synapsin I with the cytoskeleton. Both calmoddin and phosphorylation control the enhancement of actin polymerisation by synapsin I. Calmoddin in concentrations up to 3pM suppressed the enhancement of polymerisation by each phosphorylated form of synapsin I: both synapsin’s endogenous nucleating activity, and promotion of polymerisation of actin grown h m F-actin seeds were suppressed. By contrast, the addition of C a z + / ~ o d u l i n (1-10cl~) to synaptic vesicle preparations did not significantly displace endogenous synapsin I or II fhm the synaptic vesicle membranes. These data indicate that Caz+/calmodUlin selectively regulates the interaction of synapsin I with the cytoskeleton. 0 50 loo l50 Time (seconds) incrwing [-in]
Valuation and Parities for Exchange Options

Valuation and parities for both European-style and American-style exchange options are presented in a general financial model allowing for jumps, the possibility of default, and “bubbles” in asset prices. The formulas are given via expectations of auxiliary probabilities using the change-of-numeraire technique. Extensive discussion is provided regarding the way that folklore results such as Merton's no-early-exercise theorem and traditional parities have to be altered in this more versatile framework.
Un nouvel instrument d'auto-évaluation des organisations : le bilan sociétal

Le bilan societal repond au besoin d’evaluer le comportement social et environnemental des organisations. Il s’agit d’une demarche s’appuyant sur un referentiel d’auto-evaluation qui peut etre etendue aux parties prenantes de l’organisation. Instrument inedit, il constitue une innovation manageriale a la fois par sa methodologie d’elaboration et par ses developpements en dehors de son champ de conception.
Options, Futures, and Other Derivatives

Contents: Introduction. Futures Markets and the Use of Futures for Hedging. Forward and Futures Prices. Interest Rate Futures. Swaps. Options Markets. Properties of Stock Option Prices. Trading Strategies Involving Options. Introduction to Binomial Trees. Model of the Behavior of Stock Prices. The Black-Scholes Analysis. Options on Stock Indices, Currencies, and Futures Contracts. General Approach to Pricing Derivatives. The Management of Market Risk. Numerical Procedures. Interest Rate Derivatives and the Use of Black's Model. Interest Rate Derivatives and Models of the Yield Curve. Exotic Options. Alternatives to Black-Scholes for Option Pricing. Credit Risk and Regulatory Capital. Review of Key Concepts.
Homogeneous, Urban Heterogeneous, or both? External Economies and Regional Manufacturing Productivity in Europe

The objective of this paper is to analyse theoretically and empirically the effects of sectoral homogeneity and urban heterogeneity on regional manufacturing “pure” productivity differentials. Hypotheses of the existence and co-existence of the two types of external effects are formulated and tested for the regions of 13 Western EU countries by means of panel data spatial econometric techniques. The outcomes clearly support our conjectures and also reveal how a simply strong manufacturing sector, i.e., not accounting for internal specialisation, may be harmful to productivity. This result, and the existence of heterogeneous externalities, are confirmed for a sample of regions extended to Eastern European countries.
Correlation between expression of antibodies to histone H2B and clinical activity in HIV‐infected individuals

Levels of autoantibodies specific for the histone, H2B, were measured in individuals with HIV infection. In comparison with normal (uninfected) controls, infected patients, particularly those with symptomatic disease, had significantly elevated titres of anti‐H2B antibodies. Longitudinal studies confirmed that levels of these antibodies were highest in patients with lymphadenopathy and declined with the development of AIDS. In preliminary experiments designed to determine the biological significance of the anti‐histone antibodies, H2B was shown to be immunologically cross‐reactive with an 18‐kD antigen on the surface of HIV‐infected or mitogen‐activated CD4+ cells. Protein sequencing of the 18‐kD antigen has since shown complete homology with histone H2B. Because the titres of H2B autoantibodies were found to parallel the numbers of circulating CD4 cells, it is possible that these antibodies are involved in the destruction of the helper/inducer T lymphocyte population.
Human Platelets Express Functional &agr;7-Nicotinic Acetylcholine Receptors

Objective—Nicotinic acetylcholine receptors, especially &agr;7 (nAChR&agr;7), form Ca2+ channels and are expressed on a variety of neuronal and nonneuronal cells. Also, megakaryocytic cells have been shown to contain components of a nonneuronal cholinergic system, including acetylcholine and acetylcholine esterase. However, the corresponding nAChRs and their role in platelet function have not been demonstrated until now. Our previous platelet transcriptome data indicated the presence of nAChR gene transcripts. Methods and Results—Here, we present evidence that human platelets and megakaryocytic precursor cells express nAChR&agr;7 subunits, as revealed by mRNA and protein expression. The subunits form functional Ca2+ channels, as demonstrated by Ca2+ entry in platelets induced by the nAChR&agr;7-selective agonist PNU-282987. PNU-282987 also enhanced fibrinogen receptor activation induced by classical platelet agonists (the thromboxane A2 analog U46619 and ADP). Furthermore, agonist-induced platelet aggregation was significantly inhibited by the nAChR&agr;7-selective antagonists &agr;-bungarotoxin and methyllycaconitine. Conclusion—Ca2+ influx via nAChR&agr;7 channels represents a novel pathway for human platelets with significant impact on platelet function. Because platelets were suggested to contain acetylcholine, we conclude that on activation, stored acetylcholine is released, which activates nAChR&agr;7 channels and thereby contributes to maintaining intracellular Ca2+ levels and supporting platelet activation.
Circadian rhythms synchronise intracellular calcium dynamics and ATP production for facilitating Arabidopsis pollen tube growth

Experimental evidences support that the circadian rhythm regulates the transcription levels of genes encoding the enzymes involved in plant metabolism. However, there is no paper to refer the correlation of the circadian rhythms and the metabolic processes for facilitating pollen tube growth. In this study, we found that many central components of the circadian clock were highly enriched and specifically present in the in vivo grown Arabidopsis pollen tubes. Our analysis also identified the significant differentially expressed genes encoding co-expressed enzymes in the consecutive steps of fatty acid β-oxidation II, pentose phosphate pathway (oxidative branch) and phosphatidic acid biosynthesis pathway in the in vivo grown Arabidopsis pollen tubes during pollination. Thus, it is implicated that the circadian rhythms of pollen tube may be adjusted and have a greater probability of the direct or indirect functional relationship with enhanced intracellular Ca2+ dynamics and ATP production for facilitating pollen tube growth in vivo.
The embryonic development of the cnidarian Hydractinia echinata

With the rapid increase of the quantity of molecular data, many animals joined the ranks of the so‐called ‘emerging models’ of Evo‐Devo. One of the necessary steps in converting an emerging model into an established one is gaining comprehensive knowledge of its normal embryonic development. The marine colonial hydrozoan Hydractinia echinata – an excellent model for research on stem cells, metamorphosis, and allorecognition – has been studied for decades. Yet knowledge of its embryonic development remains fragmentary and incomplete. Here we provide a detailed account of H. echinata embryonic development using in vivo observations, histology, immunohistochemistry, and electron microscopy. Furthermore, we propose a model describing the cellular basis of the morphogenetic movements occurring during development and also reveal a functional link between canonical Wnt signaling and regional differences in the morphology of the embryo. Hydractinia embryogenesis is an example of the diversity and plasticity of hydrozoan development where multiple routes lead to the same result – the formation of a normal planula larva.
Leisure time activity of Mexican Americans with diabetes.

BACKGROUND Diabetes is a worldwide health problem with increasing prevalence, particularly among ethnic minorities. Activity is a major component of diabetes management that can help to prevent the deadly complications of the disease. Assessment of the activities in which individuals with diabetes from specific ethnic groups such as Mexican Americans engage may facilitate identification of strategies to encourage activity among those who do not participate in activity or have only minimal, sporadic participation. AIMS The aims of this research were to determine: (1) What proportion of Mexican Americans with diabetes do and do not exercise? (2) What are the preferred types of leisure time activity by gender and age? (3) What the relationship is between leisure time activity and treatment of diabetes? METHODS AND INSTRUMENT: A secondary analysis of data from the third National Health and Nutrition Examination Survey (NHANES) (1988-1994) was conducted to explore leisure time activities of self-identified Mexican Americans with diabetes. RESULTS Mexican American adults in this study indicated gardening (33.7%) and walking (31.5%) as the leisure time activities in which they engaged most frequently in the month preceding data collection. Gardening and walking were frequent leisure activities of study participants for all categories of pharmacological management of the diabetes. Many did not participate in any leisure time activity in the month preceding data collection. Only six of every 10 Mexican Americans (61%) with diabetes exercised. Males (n = 136; 71%) were more likely to engage in physical activity than females (n = 171; 54%). LIMITATIONS Only leisure time activity was assessed; occupational activity and household activity were not included. Data were based on self-report rather than an objective measure of subject activity. Subject knowledge of the need for activity as a component of diabetes management was not assessed and may not be recognized as an integral part of care. CONCLUSIONS Diabetes is a significant health problem for many ethnic groups, including the Mexican American population, and regular physical activity is a critical component of disease management. Facilitating activity in this ethnic group is integral to controlling complications of this chronic disease.