Miracle-dz/UniFAR-FTUs huggingface dataset:
Stress assessment based on EEG univariate features and functional connectivity measures

The biological response to stress originates in the brain but involves different biochemical and physiological effects. Many common clinical methods to assess stress are based on the presence of specific hormones and on features extracted from different signals, including electrocardiogram, blood pressure, skin temperature, or galvanic skin response. The aim of this paper was to assess stress using EEG-based variables obtained from univariate analysis and functional connectivity evaluation. Two different stressors, the Stroop test and sleep deprivation, were applied to 30 volunteers to find common EEG patterns related to stress effects. Results showed a decrease of the high alpha power (11 to 12 Hz), an increase in the high beta band (23 to 36 Hz, considered a busy brain indicator), and a decrease in the approximate entropy. Moreover, connectivity showed that the high beta coherence and the interhemispheric nonlinear couplings, measured by the cross mutual information function, increased significantly for both stressors, suggesting that useful stress indexes may be obtained from EEG-based features.
The North Pacific Gyre Oscillation and Mechanisms of its Decadal Variability in CMIP5 Models

AbstractBased on the Simple Ocean Data Assimilation (SODA) product and 37 models from phase 5 of the Coupled Model Intercomparison Project (CMIP5) database, the North Pacific Gyre Oscillation (NPGO) and its decadal generation mechanisms are evaluated by studying the second leading modes of North Pacific sea surface height (SSH) and sea level pressure (SLP) as well as their dynamical connections. It is found that 17 out of 37 models can well simulate the spatial pattern and decadal time scales (10–30 yr) of the NPGO mode, which resembles the observation-based SODA results. Dynamical connections between the oceanic mode (NPGO) and the atmospheric mode [North Pacific Oscillation (NPO)] are strongly evident in both SODA and the 17 models. In particular, about 30%–40% of the variance of the NPGO variability, which generally exhibits a preferred time scale, can be explained by the NPO variability, which has no preferred time scale in most models.Two mechanisms of the decadal NPGO variability that had been propo.
Relationship between age and serum lipids in malnourished and well-fed pre-school children in Zaria, Nigeria.

OBJECTIVE The objective of this study was to evaluate the relationship between age and serum total cholesterol (TC) and triglyceride (TG) in malnourished and well-fed pre-school Nigerian children in Zaria, northern Nigeria. MATERIALS AND METHODS Serum total cholesterol (TC) and TG concentrations were measured in 115 malnourished and 115 age- and gender-matched well-fed children aged one (1)-three (3) years. These consisted of 25, 30, 30 and 30 children with kwashiorkor, marasmic-kwashiorkor, marasmus and underweight, respectively with their corresponding age- and gender-matched well-fed children. There were 60 males and 55 females each of malnourished and well-fed children. Concentrations of TC and TG were measured by enzymatic colorimetric method using reagent kits supplied by HUMAN, Gesel Für Biochemical Und Diagnostica mbH (Wiesbaden, Germany). RESULTS There was no correlation between age and serum TC in malnourished children (r = 0.0101, p = 0.9250), while the correlation was negative and significant in well-fed children (r = 0.3599, p = 0.3110). Similarly, there was no correlation between age and serum TG in malnourished chidren (r = 0.0605, p = 0.4623) but negative and significant correlation in well-fed children (r = 0.3210, p = 0.0001). CONCLUSION The findings of this study demonstrate that in well-fed pre-school children, serum lipids decrease with advancing age and that this pattern was abolished in malnourished children. This contribution should be noted and considered when interpreting serum lipid results in children.
The influence of net charge and charge distribution on cellular uptake and cytosolic localization of arginine-rich peptides

Properties of different arginine-rich peptides, including net charge and charge distribution, were evaluated for their influence on surface binding, internalization, and intracellular localization. The peptides were radiolabeled and subsequently tested for surface binding and internalization in CHO-K1 cells. Subcellular fractionation assays were performed to separate the amount of peptides associated within vesicles from those inside the cytosol. Net neutral charged peptides, YGR6E6 and YG(RE)6, showed large decreases in both surface binding and cell uptake compared to their net positive charged counterparts, YGR6G6 and YG(RG)6. The peptides with clustered arginine residues, YGR6G6 and YGR6E6, exhibited significantly higher binding and uptake than those with alternating arginine and glycine/glutamate residues, YG(RG)6 and YG(RE)6. The intracellular distribution analysis for all of the peptides tested showed that, regardless of the net uptake, the arginine-rich peptides were preferentially localized in the cytosolic compartment of the cells. Both net positive charge and a clustered arginine sequence enhance the surface binding and internalization of peptides; however, the cytosolic versus vesicular intracellular distribution does not change. The results presented in this report provide important information regarding the specificity of binding and internalization of arginine-rich peptides, which is necessary for the future design of targeted drug delivery systems.
SYSTEMATIZATION OF U-Pb ZIRCON AGES OF GRANITOIDS FROM THE COPPER PORPHYRY DEPOSITS ON THE URALS

Проведено обобщение U-Pb возрастов цирконов из медно-порфировых месторождений восточного склона Урала. Утвержденные запасы в наиболее крупных из них составляют 1.4–1.8 млн тонн Cu (при среднем содержании 0.4–0.6 мас. %). Порфировое оруденение приурочено к небольшим массивам кварц-диоритового состава, локализованным исключительно в пределах субмеридиональных вулканогенных зон островодужного типа, разделяющихся сиалическими зонами. U-Pb датирование проводилось методом LA ICP-MS в Институте Наук о Земле Университета Иоганна Вольфганга Гёте (г. Франкфурт-на-Майне, Германия); на приборе SHRIMP-II CПб, ВСЕГЕИ, Россия; на приборе SHRIMP-IIe/mc в лаборатории IBERSIMS, Университет Гранады, Испания. На Южном Урале в латеральном разрезе с запада на восток (на расстоянии около 160 км) возраст кварцевых диорит-порфиров отдельных месторождений уменьшается от D1–2 (390 и 380 млн лет, Гумешевское и небольшое Вознесенское месторождения) в Тагило-Магнитогорской мегазоне до D2–C1 (362 и 356 млн лет, крупное Михеевское месторождение, Тарутинское месторождение) в восточной части Восточно-Уральской вулканогенной мегазоны и C1 (336 и 335 млн лет, Бенкалинское, Жалтыркольское месторождения) в Валерьяновской мегазоне. Кроме того, в западной части Восточно-Уральской вулканогенной мегазоны (в Увельской аллохтонной тектонической структуре) находятся рудоносные порфировые кварц-диоритовые массивы S1–2 возраста. К ним приурочен крупный промышленный Томино-Березняковский рудный узел с эпитермальной и порфировой минерализацией (427–429 млн лет) и находящееся в 25 км южнее Зеленодольское порфировое месторождение (418 млн лет). В указанном направлении меняется и рудная специфика: Cu-(Au)и Au-Cu-порфировые месторождения сменяются Cu-(Au, Mo)-порфировыми. В пределах Магнитогорской зоны от раннек позднеостродужной стадии возраст рудоносных гранитоидов уменьшается (390, 381, 374 и 362 млн лет) при смене их состава от кварц-диоритового до шошонитового. Изотопные и петрогеохимические данные свидетельствуют о том, что рассматриваемый островодужный тип диоритов является, возможно, результатом селективного плавления метабазальтов нижней коры или деплетированной мантии (мантийного клина). Такое плавление происходило неоднократно по мере смещения во времени источника плавления с запада на восток Урала.
A Location Selection Policy of Live Virtual Machine Migration for Power Saving and Load Balancing

Green cloud data center has become a research hotspot of virtualized cloud computing architecture. And load balancing has also been one of the most important goals in cloud data centers. Since live virtual machine (VM) migration technology is widely used and studied in cloud computing, we have focused on location selection (migration policy) of live VM migration for power saving and load balancing. We propose a novel approach MOGA-LS, which is a heuristic and self-adaptive multiobjective optimization algorithm based on the improved genetic algorithm (GA). This paper has presented the specific design and implementation of MOGA-LS such as the design of the genetic operators, fitness values, and elitism. We have introduced the Pareto dominance theory and the simulated annealing (SA) idea into MOGA-LS and have presented the specific process to get the final solution, and thus, the whole approach achieves a long-term efficient optimization for power saving and load balancing. The experimental results demonstrate that MOGA-LS evidently reduces the total incremental power consumption and better protects the performance of VM migration and achieves the balancing of system load compared with the existing research. It makes the result of live VM migration more high-effective and meaningful.
Correlation between mandibular trabeculae bone density on panoramic radiograph and body mass index of men aged 5-35 years old

Objective: Finding the correlation between mandibular trabeculae bone density on panoramic radiograph and body mass index of men aged 5-35 years old. Material and Methods: The population of this study was male patients aged 5-35 years old who performed panoramic radiography at Radiology Installation of Faculty of Dentistry at Dental Hospital Padjadjaran University (UNPAD) with a total of 62 samples. ImageJ software was used to calculate the bone density and BMI values were calculated using the BMI formula. Results: The score of body mass index increased with age meanwhile the score of mandibular trabeculae bone density decreased. Conclusion: The r-value of this study was -0.341. There was no correlation between mandibular trabeculae bone density on panoramic radiographs and body mass index of men aged 5-35 years old.
A Novel adaptive Checkpointing method based on Information obtained from Workflow Structure

Scientific workflows are data- and compute-intensive; thus, they may run for days or even weeks on parallel and distributed infrastructures such as grids, supercomputers, and clouds. In these high-performance computing infrastructures, the number of failures that can arise during scientific-workflow enactment can be high, so the use of fault-tolerance techniques is unavoidable. The most-frequently used fault-tolerance technique is taking checkpoints from time to time; when failure is detected, the last consistent state is restored. One of the most-critical factors that has great impact on the effectiveness of the checkpointing method is the checkpointing interval. In this work, we propose a Static (Wsb) and an Adaptive (AWsb) Workflow Structure Based checkpointing algorithm. Our results showed that, compared to the optimal checkpointing strategy, the static algorithm may decrease the checkpointing overhead by as much as 33% without affecting the total processing time of workflow execution. The adaptive algorithm may further decrease this overhead while keeping the overall processing time at its necessary minimum.
Labour Force Projections: A Case for the Greater Metropolitan Area of New South Wales to 2031

There is a fundamental gap in our understanding of the complexity and uncertainty in projecting and analysing the supply of labour at a regional level due mainly to the lack of longitudinal data and difficulties in determining suitable models for predictions. This study takes the Greater Metropolitan Area (GMA) of New South Wales as a case study to investigate feasible methods to project the future workforce in a region. The study applies a historical-comparative approach to deriving information about trends of labour participation and workforce status in the GMA from the panel datasets collected at national and state levels. It uses Growth curve models and cohort analysis methods for the projections of the rates of labour participation, part-time employment and unemployment among different age groups by sex. It demonstrates that the Growth curve models and cohort analysis methods provide effective methodologies and techniques to project the future labour supply at a regional level. Econlit subject descriptors: J210, J100, C610
Factors predicting outcome of rheumatoid arthritis: results of a followup study.

OBJECTIVE To determine prognostic factors in rheumatoid arthritis (RA). METHODS One hundred thirty-two women with definite RA were followed yearly from an early phase of the disease (symptoms < 5 years) for a mean duration of 6 years. The prognostic value of the first available clinical and laboratory variables and assessments of functional ability was related to several outcome measures (physician's opinion of disease severity, disease activity, radiological abnormalities, functional ability and number of prescribed 2nd-line drugs) by single predictor analysis and by logistic regression. RESULTS The variables most predictive for one or more of the outcome measures were number of swollen joints, Ritchie score, health assessment questionnaire score, radiographical abnormalities, positive IgM rheumatoid factor (RF), positive IgG-RF, HLA-DR4, and an elevated percentage serum agalactosyl IgG. The accuracy of predicting outcome was calculated from several combinations of these variables, and varied between 70 and 80%. The accuracy based on a combination of the commonly available variables (number of swollen joints, IgM-RF and the erosion score), closely approximated the maximal accuracy that could be achieved. CONCLUSION The outcome of RA can be predicted by a combination of variables that are commonly available in the clinical setting.
ffects of Loop Diuretics on yocardial Fibrosis and Collagen ype I Turnover in Chronic Heart Failure

OBJECTIVES This individually randomized, open-label, parallel-group pilot study was designed to test the hypothesis that the ability of loop diuretics to interfere with cardiac fibrosis in chronic heart failure (CHF) may be different between compounds. BACKGROUND The apparent mortality and cardiac benefits seen in studies comparing torasemide with furosemide in CHF suggest that torasemide may have beneficial effects beyond diuresis (e.g., on the process of cardiac fibrosis). METHODS Patients with New York Heart Association functional class II to IV CHF received diuretic therapy with either 10 to 20 mg/day oral torasemide (n 19) or 20 to 40 mg/day oral furosemide (n 17), in addition to their existing standard CHF therapy for eight months. At baseline and after eight months, right septal endomyocardial biopsies were obtained to quantify collagen volume fraction (CVF) with an automated image analysis system. Serum carboxy-terminal peptide of procollagen type I (PIP) and serum carboxy-terminal telopeptide of collagen type I (CITP), indexes of collagen type I synthesis and degradation, respectively, were measured by specific radioimmunoassays. RESULTS In torasemide-treated patients, CVF decreased from 7.96 0.54% to 4.48 0.26% (p 0.01), and PIP decreased from 143 7 to 111 3 g/l (p 0.01). Neither CVF nor PIP changed significantly in furosemide-treated patients. In all patients, CVF was directly correlated with PIP (r 0.88, p 0.001) before and after treatment. No changes in CITP were observed with treatment in either group. CONCLUSIONS These findings suggest that loop diuretics possess different abilities to reverse myocardial fibrosis and reduce collagen type I synthesis in patients with CHF. (J Am Coll Cardiol 2004;43:2028–35) © 2004 by the American College of Cardiology Foundation
Stability and Hypothesis Transfer Learning

We consider the transfer learning scenario, where the learner does not have access to the source domain directly, but rather operates on the basis of hypotheses induced from it - the Hypothesis Transfer Learning (HTL) problem. Particularly, we conduct a theoretical analysis of HTL by considering the algorithmic stability of a class of HTL algorithms based on Regularized Least Squares with biased regularization. We show that the relatedness of source and target domains accelerates the convergence of the Leave-One-Out error to the generalization error, thus enabling the use of the Leave-One-Out error to find the optimal transfer parameters, even in the presence of a small training set. In case of unrelated domains we also suggest a theoretically principled way to prevent negative transfer, so that in the limit we recover the performance of the algorithm not using any knowledge from the source domain.
Physiological consequences of the salmon louse (Lepeophtheirus salmonis) on juvenile pink salmon (Oncorhynchus gorbuscha): implications for wild salmon ecology and management, and for salmon aquaculture

Pink salmon, Oncorhynchus gorbuscha, are the most abundant wild salmon species and are thought of as an indicator of ecosystem health. The salmon louse, Lepeophtheirus salmonis, is endemic to pink salmon habitat but these ectoparasites have been implicated in reducing local pink salmon populations in the Broughton Archipelago, British Columbia. This allegation arose largely because juvenile pink salmon migrate past commercial open net salmon farms, which are known to incubate the salmon louse. Juvenile pink salmon are thought to be especially sensitive to this ectoparasite because they enter the sea at such a small size (approx. 0.2 g). Here, we describe how ‘no effect’ thresholds for salmon louse sublethal impacts on juvenile pink salmon were determined using physiological principles. These data were accepted by environmental managers and are being used to minimize the impact of salmon aquaculture on wild pink salmon populations.
Interrelations Among Dimensions of Ethnic-Racial Identity During Adolescence

Two approaches to conceptualizing ethnic-racial identity development dominate the literature within developmental psychology—1 focused on the process of ethnic-racial identity development, including exploration and commitment, and another focused on the evaluative components of identity, including private and public regard. In this study, we examined the interrelations among exploration, commitment, private regard, and public regard across three years in an ethnically diverse sample of Black, Dominican, Chinese, and White early adolescents. To examine the temporal precedence of multiple identity components, we used autoregressive latent trajectory analysis, which estimated time specific relationships, as well as covariation between latent factors. Findings indicated significant cross-time relationships among all identity components. For the most part, exploration predicted commitment, private regard, and public regard but not the reverse. Relationships between commitment and regard were reciprocal. Findings varied across ethnic-racial groups. We discuss the implications of our work for understanding identity processes.
Glucose-6-phosphate dehydrogenase deficiency in pleiotropic carbohydrate-negative mutant strains of Rhizobium meliloti

Several mutant strains of Rhizobium meliloti isolated after nitrosoguanidine mutagenesis were selected as unable to grow on mannose. Some of them also failed to grow on glucose, fructose, ribose, and xylose but grew on L-arabinose, galactose, and many other carbon sources. Biochemical analysis demonstrated that the mutants lacked NAD- and NADP-linked glucose-6-phosphate dehydrogenase activities that reside on a single enzyme species. One such mutant was found to accumulate glucose-6-phosphate, and this could partially explain the inhibition of growth observed on mixtures of permissive and nonpermissive carbon sources. Symbiotic properties remained unaffected in all these mutants.
Helper T cells are required for the polyclonal stimulation of cytotoxic T cells by concanavalin A

Concanavalin A stimulation of T-cell cytotoxicity has been shown to be absolutely dependent on helper T-cell collaboration. Thymocytes stimulated with ConA do not differentiate to yield cytotoxic effector cells. However, thymocytes cocultured with irradiated spleen cells as helpers and ConA yield high levels of cytotoxicity. The helper cell bears theta antigens on its surface, is not an adherent cell, and does not require any adherent cell functions in our culture conditions. The ConA-dependent helper cells appear to be polyclonal in specificity. Thus, polyclonal stimulation of cytotoxicity by ConA requires T helper- T precursor collaboration in analogy to antigen-specific T helper-T precursor interactions. Unlike the antigen-specific interacitons, the ConA-driven cytotoxicity does not appear to require linked associative recognition for induction of cytotoxicity.
Natural Language Processing: part 1 of lecture notes

• Introduction. Brief history of NLP research, current applications, generic NLP system architecture, knowledgebased versus probabilistic approaches. • Finite state techniques. Inflectional and derivational morphology, finite-state automata in NLP, finite-state transducers. • Prediction and part-of-speech tagging. Corpora, simple N-grams, word prediction, stochastic tagging, evaluating system performance. • Parsing and generation I. Generative grammar, context-free grammars, parsing and generation with contextfree grammars, weights and probabilities. • Parsing and generation II. Constraint-based grammar, unification, simple compositional semantics. • Lexical semantics. Semantic relations, WordNet, word senses, word sense disambiguation. • Discourse. Anaphora resolution, discourse relations. • Applications. Machine translation, email response, spoken dialogue systems.
QUANTITATIVE DETECTION OF STAPHYLOCOCCAL ENTEROTOXIN B IN FOOD BY GEL-DIFFUSION METHODS.

RECOVERY of coagulase-positive StaphyloCOCCUs aureus from food implicated in a foodpoisoning outbreak is only circumstant. ,ial evidence that the correct etiological agent has been found. Even the determination by animal studies that the strain isolated is capable of producing enterotoxin doeis not prove that it did so in the food. Positive proof depends on demonstration of the enterotoxin in the food itself. Such proof can be obtained by feeding the food to monkeys or human volunteers, but the results are subject to the variations in susceptibility known to occur among both test subjects. The purification (1) of Enterotoxin. B, S6 type ["E" type of Casman (2) ] and t,he determination that it was an antigenically act-ive protein (.3-5) opened t.he way to use of serologic methods for direct detection of enterotoxin in foods. Although Enterotoxin B occurs in food infrequently (2,6) compared with the frequency of Enterotoxin A, 196E type ["F" type of Casman (2)], it is a useful substitute for preliminary studies because it can be produced in a highly purified form. This report deals with the results obtained and the difficulties encountered in the use of the various gel-diffusion techniques for the, direct serologic detection and quantification of 'Enterotoxin B in foods.