Miracle-dz/UniFAR-FTUs huggingface dataset:
Alcohol Consumption and Viral Load Are Synergistically Associated with CIN1

Purpose We investigated the association between alcohol consumption and risk of cervical intraepithelial neoplasia (CIN) and cervical cancer, and determined whether these associations were modified by human papillomavirus (HPV) viral load in high-risk HPV-positive women participating in the Korean HPV cohort study (KHPV). Methods Among the women recruited in the KHPV (n = 1,243) from March 2006 to December 2009, we analyzed normal cytology (n = 581) as control group, CIN1 (n = 299), CIN2/3 (n = 161), or cervical cancer (n = 202). Multinomial logistic analysis was performed to estimate multivariate-adjusted odds ratios (OR). Results Alcohol drinkers had an increased risk of CIN1 (OR = 2.18, 95% CI 1.22–3.89) compared with non-drinkers after adjusting for potential confounders. Subjects with more frequent alcohol consumption had a higher risk of CIN1 (p for linear trend <0.0001). Higher ethanol consumption was associated with an increased risk of CIN1 (p for linear trend = 0.0001). We also observed a synergistic effect between HPV viral load and alcohol consumption: drinkers with a high HPV viral load (≥100 RLU/PC) were associated with a significantly increased risk of CIN1 (OR = 19.1; 95% CI, 6.60–55.3, interaction p<0.001). There were no associations between alcohol drinking and CIN2/3 or cervical cancer. Conclusions HPV viral load and alcohol was associated with the risk of CIN1 among high-risk HPV-positive women. This is the first demonstration that alcohol is an independent and combined risk factor of CIN1.
Humour's role in the relation between attributional style and dysphoria

The present study empirically investigated the role of adaptive and maladaptive components of humour in the relation between attributional style and dysphoria. Four hundred eighteen students (134 male, 282 female; 2 respondents did not indicate gender) completed questionnaires measuring attributional style, humour styles and depressive symptoms. Among men and women, higher levels of affiliative and self‐enhancing humour, and lower levels of self‐defeating humour, were each associated with fewer depressive symptoms. Additionally, higher levels of affiliative humour provided a buffer against the deleterious effects of a negative attributional style in men, but not women. Copyright © 2006 John Wiley & Sons, Ltd.
Collective Production and Provision

omy, the distinctions between self-interest and collective action can become blurred. Many objectives can be achieved only through the workings of the free enterprise system; others through the operations of the state. Of particular interest here is the cooperative enterprise-an organizational form that allows for collectivization of wants and needs while sustaining and enhancing the freedoms inherent in
Precise numerics versus theory for correlation ratchets.

Fluctuation-induced transport in a correlation ratchet driven by both additive Gaussian white and additive Ornstein-Uhlenbeck (colored) noise is studied numerically and interpreted against theoretical predictions. The current as well as the current-load curve exhibit a different behavior depending on the scaling of the colored noise strength. This archetypal correlation ratchet is capable of changing the direction of current (passing through zero at a particular value of noise color) if only the {ital shape} of the ratchet potential is chosen appropriately. {copyright} {ital 1996 The American Physical Society. }
Research Paper: Knowledge-based Approaches to the Maintenance of a Large Controlled Medical Terminology

OBJECTIVE Develop a knowledge-based representation for a controlled terminology of clinical information to facilitate creation, maintenance, and use of the terminology. DESIGN The Medical Entities Dictionary (MED) is a semantic network, based on the Unified Medical Language System (UMLS), with a directed acyclic graph to represent multiple hierarchies. Terms from four hospital systems (laboratory, electrocardiography, medical records coding, and pharmacy) were added as nodes in the network. Additional knowledge about terms, added as semantic links, was used to assist in integration, harmonization, and automated classification of disparate terminologies. RESULTS The MED contains 32,767 terms and is in active clinical use. Automated classification was successfully applied to terms for laboratory specimens, laboratory tests, and medications. One benefit of the approach has been the automated inclusion of medications into multiple pharmacologic and allergenic classes that were not present in the pharmacy system. Another benefit has been the reduction of maintenance efforts by 90%. CONCLUSION The MED is a hybrid of terminology and knowledge. It provides domain coverage, synonymy, consistency of views, explicit relationships, and multiple classification while preventing redundancy, ambiguity (homonymy) and misclassification.
Clonal stability of blood cell lineages indicated by X-chromosomal transcriptional polymorphism

The idea that stem cells oscillate between a state of activity and dormancy, thereby giving rise to differentiating progeny either randomly or in orderly clonal succession, has important implications for understanding normal hematopoiesis and blood cell dyscrasias. The degree of clonal stability in individuals also has practical implications for the evaluation of clonal lymphomyeloproliferative diseases. To evaluate the clonality pattern of the different types of blood cells as a function of time we have validated the applicability, sensitivity, and reproducibility of a thermostable ligase reaction to detect transcripts of the G6PD allele on the active X-chromosome in normal heterozygous females. While the ratio of the two X-chromosome- derived allelic transcripts varied widely among hemopoietic tissues in a given individual, this allelic ratio was virtually identical in all types of mature myeloid and lymphoid cells. Longitudinal studies indicated constancy of the G6PD allelic ratio in blood cells over a 912- d period of observation in healthy females. The individual variability observed in this allelic ratio suggests that the progeny of a relatively small number of original embryonic hemopoietic stem cells, approximately eight, contribute to the sustained production of all types of blood cells in healthy individuals.
Exploring managerial success factors of Chinese managers: a comparison between mainland and Hong Kong Chinese males

Recent research has identified the major activities and factors that contribute to the success of managerial performance and growth. However, because of cultural differences, it is unwise to generalize such findings to the managerial population in Chinese societies. No comparable study of this sort has been carried out in the PRC. This research study seeks to find out what managerial success factors, as perceived by male managers in two regions in the PRC are the most influential in their rise to senior management positions. The study also compares factors perceived to be important in developing managers in Hong Kong and Guangdong.
CD151-α3β1 integrin complexes are prognostic markers of glioblastoma and cooperate with EGFR to drive tumor cell motility and invasion

Glioblastoma, one of the most aggressive forms of brain cancer, is featured by high tumor cell motility and invasiveness, which not only fuel tumor infiltration, but also enable escape from surgical or other clinical interventions. Thus, better understanding of how these malignant traits are controlled will be key to the discovery of novel biomarkers and therapies against this deadly disease. Tetraspanin CD151 and its associated α3β1 integrin have been implicated in facilitating tumor progression across multiple cancer types. How these adhesion molecules are involved in the progression of glioblastoma, however, remains largely unclear. Here, we examined an in-house tissue microarray-based cohort of 96 patient biopsies and TCGA dataset to evaluate the clinical significance of CD151 and α3β1 integrin. Functional and signaling analyses were also conducted to understand how these molecules promote the aggressiveness of glioblastoma at molecular and cellular levels. Results from our analyses showed that CD151 and α3 integrin were significantly elevated in glioblastomas at both protein and mRNA levels, and exhibited strong inverse correlation with patient survival (p < 0.006). These adhesion molecules also formed tight protein complexes and synergized with EGF/EGFR to accelerate tumor cell motility and invasion. Furthermore, disruption of such complexes enhanced the survival of tumor-bearing mice in a xenograft model, and impaired activation of FAK and small GTPases. Also, knockdown- or pharmacological agent-based attenuation of EGFR, FAK or Graf (ARHGAP26)/small GTPase-mediated pathways markedly mitigated the aggressiveness of glioblastoma cells. Collectively, our findings provide clinical, molecular and cellular evidence of CD151-α3β1 integrin complexes as promising prognostic biomarkers and therapeutic targets for glioblastoma.
A RELAXED WISHART MODEL FOR POLARIMETRIC SAR DATA

In this paper we demonstrate that simple yet exible modelling of multilook polarimetric synthetic aperture radar (PolSAR) data can be obtained through a relaxation of the Wishart model. The degrees of freedom of the complex Wishart distribution is treated as a spatially nonstationary parameter, which is allowed to vary between thematic classes and segments of the PolSAR scene.
English-Latvian SMT: knowledge or data?

In cases when phrase-based statistical machine translation (SMT) is applied to languages with rather free word order and rich morphology, translated texts often are not fluent due to misused inflectional forms and wrong word order between phrases or even inside the phrase. One of possible solutions how to improve translation quality is to apply factored models. The paper presents work on English-Latvian phrase-based and factored SMT systems and, using evaluation results, demonstrates that although factored models seem more appropriate for highly inflected languages, they have rather small influence on translation results, while using phrase-model with more data better translation quality could be achieved.
Serial Killing Myths Versus Reality: A Content Analysis Of Serial Killer Flicks Made Between 1980 and 2001

Public perceptions about serial homicide are more mythical than fact. Myths about serial homicide are perpetuated through several sources, especially the entertainment media which is a dominant and influential mythmaker. The number of films depicting serial killers and serial killing themes has increased dramatically in recent years. However, the reality of these films is debatable. This research examines the reality, or lack thereof, of the most recent films involving a serial killing theme. Hickey provides a wealth of statistical information on a number of serial killers and serial killings. A content analysis of the fifty top grossing serial killer movies made between 1980 and 2001 was conducted using variables from Hickey research. Research shows similarities and differences between variables, however, results concludes the entertainment media does not accurately portray serial homicide.
Ground Dwelling Ants as Surrogates for Establishing Conservation Priorities in the Australian Wet Tropics

Abstract This study aims to identify a set of areas with high biodiversity value over a small spatial scale within the Australian Wet Tropics. We identified sites of high biodiversity value across an altitudinal gradient of ground dwelling ant communities using three measures of biodiversity. The three measures considered were estimated species richness, complementarity between sites and evolutionary history. The latter measure was derived using the systematic nomenclature of the ants to infer a surrogate phylogeny. The goal of conservation assessments could then be achieved by choosing the most diverse site combinations. This approach was found to be valuable for identifying the most diverse site combinations across an altitudinal gradient that could ensure the preservation of terrestrial ground dwelling invertebrates in the Australian Wet Tropics.
Deconstructing context: exposing Derrida

Deconstruction has become a theme in various strands of geographical research. It has not, however, been the subject of very much explicit commentary. This paper elaborates on some basic themes concerning the relationship between deconstruction and conceptualisations of context, with particular reference to issues of textual interpretation. The double displacement of textuality characteristic of deconstruction is discussed, followed by a consideration of the themes of ‘writing’ and ‘iterability’ as distinctive figures for an alternative spatialisation of concepts of context. It is argued that deconstruction informs a questioning of the normative assumptions underwriting the value and empirical identity of context.
Interaction of nitric oxide and the cytochrome P‐450 system on blood pressure and renal function in the rat: dependence on sodium intake

Aim: Interaction was examined of nitric oxide (NO) and cytochrome P‐450 (CYP‐450)‐dependent arachidonic acid derivatives, 20‐HETE and EETs, in control of arterial pressure (MABP) and renal function. Modification of this interaction by changing sodium intake was also studied.
Nurse Work Environments and Occupational Safety in Intensive Care Units

Using data collected from 39 intensive care units (ICUs) in 23 hospitals across the United States, the purpose of this study was to examine hospital structural characteristics, nurse characteristics, and nurses' working conditions' impact on occupational safety outcomes. ICU with more positive organizational climates had lower rates of occupational injuries and blood and body fluid exposures (p < .05). Similarly, ICUs in hospitals that had attained magnet accreditation had lower rates of negative occupational health incidents (p < .05). Hospital profitability was inversely related to rates of blood and body fluid exposure (p < .05). Monitoring nurses' working conditions and improving the organizational climate of hospitals is likely to improve the safety of the employee and the profitability of the hospital through improved system outcomes (such as lower turnover of the employees) as well as improve the quality of patient care delivered.
Regret and Elation Following Action and Inaction

In their research on decision under uncertainty, Kahneman and Tversky (1982a) examined whether, given the same negative outcome, there is any difference in the experience of regret, depending on whether the outcome follows action or inaction. This study attempted to replicate Kahneman and Tversky's (1982a) finding of greater regret for action than inaction and to determine whether this pattern extends to the parallel case of joy over happy outcomes, to different life domains, and to both genders. Through a vignette experiment, the previousfinding of a strong tendency to imagine greater regret following action than inaction was replicated. The same pattern was observed in the case of joy over positive outcomes. In two of the three vignettes presented, this "actor effect "was stronger for negative than for positive outcomes. In a third vignette, explicit knowledge of a missed negative outcome seems to have magnified the usual joy over having made a good decision, causing the expected joy over acting and succeeding to rise to the typically high level of regret over acting and failing. Suggestions regarding the future study of these issues are offered.
Mobile Learning Applications' Acceptance Model (MLAAM)

Mobile technology has the potential to enhance people's lives in India in many ways. Mobile learning (M-learning) is an extension of e-learning. There are various classifications of M-learning applications. The classification done by Deegan and Rothwell (2010) in five categories covers all the applications in education scenario. We used basic TAM model and extended it by applying these five categories as external variables. In this pilot study, we studied the acceptance of M-learning by using extended TAM model for university students in India. The study provides a theoretical research framework which addresses the value of mobile learning acceptance in the higher education environment. The focus is on how university students perceive it and to determine the factors responsible for such perceptions.
Breast tissue density quantification via digitized mammograms

Studies reported in the literature indicate that breast cancer risk is associated with mammographic densities. An objective, repeatable, and a quantitative measure of risk derived from mammographic densities will be of considerable use in recommending alternative screening paradigms and/or preventive measures. However, image processing efforts toward this goal seem to be sparse in the literature, and automatic and efficient methods do not seem to exist. Here, the authors describe and validate an automatic and reproducible method to segment dense tissue regions from fat within breasts from digitized mammograms using scale-based fuzzy connectivity methods. Different measures for characterizing mammographic density are computed from the segmented regions and their robustness in terms of their linear correlation across two different projections-cranio-caudal and medio-lateral-oblique-are studied. The accuracy of the method is studied by computing the area of mismatch of segmented dense regions using the proposed method and using manual outlining. A comparison between the mammographic density parameter taking into account the original intensities and that just considering the segmented area indicates that the former may have some advantages over the latter.
Prevalence and potential for aflatoxin contamination in groundnuts and peanut butter from farmers and traders in Nairobi and Nyanza provinces of Kenya

Objective: Most of the peanut butter marketed in Nairobi is processed in cottage industry and its aflatoxin contamination status has not been documented. This study was therefore conducted to determine the status of aflatoxin contamination in groundnuts and peanut butter in Nairobi and Nyanza. Methodology and results: Eighty two fresh samples comprising raw and roasted groundnuts and peanut butter were obtained from market outlets and cottage processors in Nairobi and Nyanza regions. The marketers and processors were asked for information on the source of groundnuts. The incidence of Aspergillus section Flavi was determined using standard laboratory methods. Defective nuts in raw groundnuts were determined by manual sorting. Aflatoxin analysis was done using competitive ELISA technique. Groundnuts in Nairobi were imported from Malawi while those Nyanza were grown in the region. The fungal species isolated from the samples were: Aspergillus flavus (L and S strains), A. parasiticus, A. niger, A. tamari, A. alliaceus , A. caeletus and Penicillium spp . The percentage of defective nuts among all unsorted groundnuts ranged from 0.0% to 26.3%. The mean percent defective nuts was higher for Nairobi samples than Nyanza. Aflatoxin levels in all samples ranged from 0 to 2377.1 µg/kg. The mean aflatoxin level was higher for raw samples from Nairobi than Nyanza. The source of groundnuts and defective nuts were positively associated with aflatoxin levels. Conclusions and application of findings: The source of groundnuts and presence of defective nuts were identified as the main factors influencing increased aflatoxin contamination in the cottage industry. Mechanisms for inspection and certification of imported groundnuts should be put in place accompanied by effective monitoring for compliance to set aflatoxins standards. All the market players should sort their groundnuts before selling or processing in order to reduce aflatoxin contamination of peanut butter.
A Review on Biometric Recognition

Biometrics introduce to the recognition of human by their characteristics. It is used to identify individuals in groups. Traditional methods of identification involving passwords and PIN numbers, this new technique of identification is preferred over them. Biometric systems are divided on the basis of medium used for authentication. Face Recognition, Iris Recognition, Palm Recognition; Voice Recognition, Fingerprint Recognition, ECG signal based recognition methods are used for identification. Different techniques are used to extract the features for recognition. This paper gives a literature survey on Biometric Identification system so that new researchers do not find the difficulty for obtaining the information.
Nanopillar array structures for enhancing biosensing performance

Fabrication of metallic nanopillar array structures and their application as electrodes in electrochemical-based biosensors are discussed in this report. Vertically standing nanopillar array structures were fabricated using an electrodeposition technique and their electrochemical characteristics were evaluated. For possible use in biosensing applications, these standing nanopillars should have sufficient mechanical stability to sustain the capillary forces caused by the nanopillar – liquid interactions in aqueous environment and should provide increased signal response in an electrochemical process. Our results showed that the developed nanopillar arrays were mechanically stable in aqueous environments and the nanostructured electrodes exhibited increased electrochemical response compared with flat electrodes.
Bereaved Families: A Comparison of Parents' and Grandparents' Reactions to the Death of a Child

Most research has dealt with the bereaved person as an individual and ignored the context in which the person grieves. The occurrence of a death in the family is experienced in various ways, depending on the nature of the relationships within the family. The purpose of this study was to investigate how different family members experience a child's death by comparing the grief reactions of parents and grandparents within the same family. Most parents and grandparents reported subjectively experiencing affective changes in reflecting on the death that did not appear to alter behavior patterns. The majority of parents mentioned that they felt or acted differently toward their surviving children as a result of the death, whereas only one third of the grandparents noted any differences toward their grandchildren. Overall, parents' reactions centered on their deceased child whereas grandparents' concerns focused on their children (i.e., the parents of the deceased child).
Disordered mind, wounded soul: The emerging role of psychotherapy in rehabilitation after brain injury

The traditional pessimism over attempting psychotherapy with brain dysfunctional individuals is being challenged. Symbols that can guide the psychotherapeutic process with these individuals are discussed and presented. The role of various art forms to enhance a better understanding of the brain dysfunctional patient's phenomenologic experiences are also considered. Establishing a sense of meaning after brain injury becomes the center point around which psychotherapeutic efforts are developed.
Significant fetal cell microchimerism in a nontransfused woman with hepatitis C: Evidence of long‐term survival and expansion

The role of fetomaternal cell trafﬁcking in diseases that predominantly affect women during pregnancy or after childbearing years has been reviewed recently. 1 The biologic signiﬁcance of persistent micro-chimeric fetal cells in parous women has been of interest since it was shown that fetal cells can remain in the maternal circulation for decades after birth. 2 As part of a study of diseases associated with fetal cell microchimerism, we analyzed liver biopsy specimens from a woman with hepatitis C for the presence of cells from her son.