Miracle-dz/UniFAR-FTUs huggingface dataset:
Multi objective optimal power flow to minimize losses and carbon emission using Wolf Algorithm

The population growth and technological advances lead to increasing demand for electrical energy is not matched by the growth of energy sources. Many ways in which to distribute electrical energy with a variety of methods to get the amount of energy efficient with an economical price. In this paper would like to introduce applications use Wolf Algorithm (WA) for optimal settings on optimal power flow control variables. The main objective was tested and tried in the standard IEEE 30-bus test system with multi objective which showed losses and carbon emission value. The results of the main goals will be compared and reported in the literature. The results are quite promising and show effectiveness and resilience of the main goal.
Macromolecular crowding: biochemical, biophysical, and physiological consequences.

CONTENTS PERSPECTIVES AND OVERVIEW 28 Nomenclature 30 THEORETICAL CONCEPTS 31 The Effect of Macromolecular C owdin9 on Solution Equilibria 31 The Effect of Macromolecular C owdin# on Reaction Rates 36 The Effect of Macromolecular Crowding on Diffusive Transport of Solutes 37 The Effective Specific Volume of a Macromolecule--What Is It? 40
Bio-molecular optimized interactions and conformational switches in human ERβ and SRC-1 protein: An in silico approach to suppress tumor in breast cancer malignancies: Computational insight for suppression of tumorigenesis in breast malignancies

A vital female hormone; estrogen activates the β-subunit of estrogen receptor protein (ERβ), which further aids in the suppression of the breast tumor cells with the aid of human SRC-1 (steroid receptor coactivator-1) protein. Though wet laboratory documentation has been documented on this regard but the molecular level studies via optimization operations remains yet unexplored. So, for the purpose, experimentally validated 3D functional structures of the two essential human proteins; ERβ and SRC-1 were extracted, demonstrated and analyzed. Protein-protein docking further led to the complex formation, which was further subjected to optimization and molecular dynamics simulation techniques. Residual contribution from the pre optimized and post optimized simulated protein-protein complex was compared and examined individually, with an additional focus on the binding patterns. The increase in the predominant ionic interactions and side chain-side chain interactions displays the optimized and simulated complex to be greatly interactive one. Mainly, polar negatively charged; Asp87 from ERβ and His1, His5 and Lys2 from SRC-1 played a pivotal role in the protein interaction mechanism after optimization followed by simulation. Statistically significant evaluations from free energy of folding, net area available for solvent accessibility, electrostatic surface potential as well as conformational transition from coils to helices in either of the two proteins additionally affirms the structures to gain stability and strength after optimization and simulation. Therefore, this present study provides a scope to view the residual interactive mode and the most stable interactive protein structures responsible for hindering the tumor proliferation in human breast cancers. For future, it further instigates the biomedical and pharmaceutical field for breast cancer malignancies.
Observations and analysis of two type IIP supernovae: the intrinsically faint object SN 2005cs and the ambiguous object SN 2005ay

Aims. To derive observational. properties and physical parameters of the progenitor stars of type IIP supernovae SN 2005ay and SN 2005cs from their U, B, V,R, I CCD photometry, and to define their velocity behaviour. Methods. Light curves are analysed, and the velocities and spectral characteristics of SN 2005cs are obtained using synthetic spectra modeling. Results. Both supernovae are found to be fainter than the average SN IIP, with SN 2005cs being more subluminous and showing slight brightening in the second half of plateau stage in the V,R,I bands and a low expansion velocity. The effects of two different plausible distance moduli on the derived physical parameters of SN 2005ay are considered. Two approaches are used to recover the amounts of the ejected 56 Ni, indicating masses of the order of ∼0.02 M ⊙ , although late luminosities might indicate a higher amount for SN 2005ay, especially for the large distance case. Constraints on the progenitor properties are also presented, based on empirical analytical models. Two approaches are used to estimate the expansion velocities at the middle of the plateau phase. SN 2005cs represents an example of where all 3 physical parameters, velocity, energy and 56 Ni mass are lower than average, a correlation not always observed in SNe IIP. SN 2005ay may belong to the same class if the shorter distance possibility is adopted. Furthermore, the estimated mass range for SN 2005cs is in agreement with limits established by using pre-supernova imaging.
Outdoor Fieldwork in Higher Education: Learning From Multidisciplinary Experience

Background: Many disciplines use outdoor fieldwork (OFW) as an experiential learning method in higher education. Although there has been an increase in research into the pedagogical approaches of OFW, the use of OFW is contested. Purpose: The purpose of the study was to synthesize the OFW literature across a range of disciplines to identify common strengths, weaknesses, opportunities, and threats (SWOT) and outline implications for how OFW is used as an experiential learning pedagogy in higher education. Methodology/Approach: A descriptive literature review was undertaken to examine each aspect of the SWOT at the micro, meso, and macro levels, drawing from disciplines using OFW including biology, outdoor and environmental education, archaeology, and the associated geosciences. Findings/Conclusions: Strengths of OFW include engagement, outreach, and professional competencies; weaknesses exist in the areas of equity, logistics, and standards. Opportunities include improving pedagogical practices, diversity, and collaboration, while threats to OFW were costs, funding, outdated practices, and governance. Implications: Academics from a range of disciplines using OFW have similar experiences; therefore, exploring ways to collaborate or learn from each other will further develop OFW as an experiential learning strategy in higher education.
Humanlike robotic vision system using artificial neural network

Robotic manipulator, which is a kind of robot that interacts with its environment in order to manipulate objects, is the most extensively-employed kind of robot in practical field. Most of the robotic manipulators functioning in the industries and other fields are programmed to manipulate objects from fixed predefined points in space. However, this might create problems in real world situation where the location of the object is arbitrary and cannot be predefined. This problem can be solved if the robot is able to recognize the object by learning which one is the specific object and which one is not. The robot can then find the position where the object is located in order to drive the manipulator tool point towards that position. In this paper, an approach has been taken to design and analyze performance of a humanlike robotic vision system for robotic manipulator using artificial neural network along with image processing. Here, the robot captures image of the environment, analyzes it and determines the points in space where the object to be manipulated is locate.
La expresión evidencial con 'así que': significado evidencial y función discursiva en la interacción

En el presente articulo se focaliza la atencion en el tipo de enunciado evidencial introducido por la conjuncion ilativa asi que (Rodriguez Ramalle 2010, 2013, 2014a, 2014b, 2015, 2016). En primer lugar, se describe el significado evidencial integrando las nociones de fuente y de acceso indirecto o mediado (Lazard 1999, 2001) con la nocion interactiva de intersubjetividad (Nuyts 2001a, 2001b, 2006, 2012). En segundo lugar, se justifica la aparicion del significado evidencial a partir de la hipotesis de una instruccion polifonica evidencial (Ducrot 1980, 1984). Por ultimo, desde el punto de vista funcional, analizamos la funcion del enunciado evidencial en la interaccion oral integrando la hipotesis de justificacion de Anderson 1986 con las nociones pragmaticas de deixis proposicional (de Haan 2005), autoridad, derecho y propiedad de la informacion (Fox 2011, Hill and Irvine 1983, Nucholls y Michael 2014) y en relacion con los fenomenos pragmaticos de la atenuacion y de la intensificacion (Briz 2003, 2007, 2011, 2016; Briz y Albelda 2013; Albelda 2016). Los datos manejados sostienen la independencia de las categorias evidencial y epistemica asi como el valor deictico de los evidenciales.
Fluorodeoxyglucose positron emission tomography may aid the diagnosis of aggressive primary prostate cancer: A case series study

Recent evidence has shown that positive results may be observed for fluorodeoxyglucose-positron emission tomography (FDG-PET) in undifferentiated, biologically aggressive and metastatic tumors. The present study describes a case series of six patients with normal prostate-specific antigen (PSA) serum levels who underwent FDG-PET due to other causes. Positive PET results were observed at the prostate and the patients were subsequently diagnosed with high-risk prostate cancer. Clinical, anamnestic, laboratory and instrumental data were collected from six asymptomatic patients with total serum PSA levels of <4 ng/ml who had undergone FDG-PET due to other causes. The FDG-PET and prostate biopsy were positive for prostate cancer. All the patients were treated with radical intent. The median age was 66 years (range, 52–72 years), the median total PSA value was 2.4 ng/ml (range, 1.5–3.9 ng/ml) and the body mass index was 26.4 (range, 21.8–30.2). Three of the six patients underwent FDG-PET due to a clinical suspicion of multiple myeloma, while three patients were examined for other oncological diseases. The pathological analysis at the prostate biopsy revealed three patients with a Gleason score of 6, two with a score of 7 (4+3) and one with a score of 8 (4+4). Five of the six patients were treated by radical prostatectomy and one by radiotherapy. The pathological analysis revealed one patient of pT2a stage, three of pT2c and one of pT3b. No patients demonstrated lymph node invasion. The definitive Gleason score was 3+3 in one patient, 4+3 in one patient, 4+4 in two patients and 5+3 in one patient. Following a median follow-up time of six months (range, 1–12 months), five of the six patients underwent FDG-PET again, which revealed negative results. At the end of this study, these patients were alive without evidence of disease. By contrast, one patient demonstrated positive FDG-PET results. In conclusion, FDG-PET has been used to characterize prostate cancers in patients with apparently normal PSA levels.
Repeated Sense of Hunger Leads to the Development of Visceral Obesity and Metabolic Syndrome in a Mouse Model

Obesity-related disorders, especially metabolic syndrome, contribute to 2.8 million deaths each year worldwide, with significantly increasing morbidity. Eating at regular times and proper food quantity are crucial for maintaining a healthy status. However, many people in developed countries do not follow a regular eating schedule due to a busy lifestyle. Herein, we show that a repeated sense of hunger leads to a high risk of developing visceral obesity and metabolic syndrome in a mouse model (both 3-week and 6-week-old age, 10 mice in each group). The ad libitum (AL) group (normal eating pattern) and the food restriction (FR) group (alternate-day partially food restriction by given only 1/3 of average amount) were compared after 8-week experimental period. The total food consumption in the FR group was lower than in the AL group, however, the FR group showed a metabolic syndrome-like condition with significant fat accumulation in adipose tissues. Consequently, the repeated sense of hunger induced the typical characteristics of metabolic syndrome in an animal model; a distinct visceral obesity, hyperlipidemia, hyperglycemia and hepatic steatosis. Furthermore, we found that specifically leptin, a major metabolic hormone, played a major role in the development of these pathological disorders. Our study indicated the importance of regular eating habits besides controlling calorie intake.
Designing for child resilience

This short case study describes the design and initial feedback of a color-changing "mood lamp" that allows children to make informed decisions about risk-taking behavior on the internet. Such a device is a case study of an attempt to improve resilience amongst unsupervised children on the internet: an important goal in child protection studies.
Pathogenesis of Renal Disease in Systemic Lupus Erythematosus—The Role of Autoantibodies and Lymphocytes Subset Abnormalities

Lupus nephritis (LN) is a common and severe organ manifestation of systemic lupus erythematosus (SLE), and is associated with significant patient morbidity and mortality. Autoantibodies and aberrations in lymphocyte subsets have putative roles in the pathogenesis of SLE and LN, and might reflect disease activity and are amenable to immunosuppressive treatments. Anti-DNA is one of the well-studied autoantibodies, which correlates with disease activity and has direct nephritogenic effects on resident renal cells and various glomerular components. Other important autoantibodies in the pathogenesis of LN include anti-C1q, anti-α-actinin and anti-nucleosome antibodies. Changes in naive and memory B cells and plasma cells have been observed in SLE and LN patients. These B cell subsets exert diverse effects during pathogenesis of LN such as production of autoantibodies, secretion of proinflammatory and anti-inflammatory cytokines and presentation of auto-antigens to effector cells. Aberration of T lymphocytes, especially the T-helper subsets, is also highly pertinent in the development of LN. In this context, important T helper subsets include Th1, Th2, Th9, Th17, TReg and follicular T-helper cells. The growing knowledge on these autoantibodies and lymphocyte subset abnormalities will enhance our understanding of SLE and LN, and hence help devise better strategies for disease monitoring and treatment.
Colloquium: Multimessenger astronomy with gravitational waves and high-energy neutrinos

Ando, S. ; Baret, B. ; Bartos, I. ; Bouhou, B. ; Chassande-Mottin, E. ; Corsi, A. ; Di Palma, I. ; Dietz, A. ; Donzaud, C. ; Eichler, D. ; Finley, C. ; Guetta, D. ; Halzen, F. ; Jones, G. ; Kandhasamy, S. ; Kotake, K. ; Kouchner, A. ; Mandic, V. ; Márka, S. ; Márka, Z. ; Moscoso, L. ; Papa, M.A.; Piran, T. ; Pradier, T. ; Romero, G.E. ; Sutton, P.; Thrane, E. ; van Elewyck, V. ; Waxman, E. DOI 10.1103/RevModPhys.85. 1401 Publication date 2013 Document Version Final published version Published in Reviews of Modern Physics
A Mixed Voltage Bidirectional I/O IP corewith low power modification for automotive BCM SoC

This paper proposed a Mixed-Voltage Bidirectional (MVB) I/O IP core for an automotive Body Control Module (BCM) SoC. It is based on a conventional bidirectional I/O circuit, four configuration signals with a constraints module, and level shifters to transform 1.8V core logic to 3.3V or 5V external logic are added. Data level shifter and input Schmitt trigger are modified to achieve low power strategy. With that strategy, this I/O could avoid any unnecessary power consumptions. This circuit will be fabricated under the TSMC automotive qualified 0. 18μm technology.
The effect of methodological variations on university rankings and associated decision-making and policy

ABSTRACT This paper explores the effect of methodological choice on global Higher Education Institutions’ (HEI) rankings, and the effect of choices regarding League Table and Ranking Systems (LTRSs) upon decision-making and policy. LTRSs are identified as heuristics to aid decision-making about HEIs. The paper examines the methodological choices commonly made within ‘rankology’. It describes the methodologies used in six popular LTRSs and the manner in which the ranking formulae were constructed. An analysis of the ranking of global HEIs by the six LTRSs for 2015 revealed that whilst there was a degree of agreement across these LTRSs regarding the ranking of two ‘elite’ institutions, the level of agreement across the LTRSs rapidly broke down as one progressed to consider institutions further down the ranking order. The study shows that the use of LTRSs to aid decisions is highly sensitive to one’s choice of LTRS.
Sae2 Function at DNA Double-Strand Breaks Is Bypassed by Dampening Tel1 or Rad53 Activity

The MRX complex together with Sae2 initiates resection of DNA double-strand breaks (DSBs) to generate single-stranded DNA (ssDNA) that triggers homologous recombination. The absence of Sae2 not only impairs DSB resection, but also causes prolonged MRX binding at the DSBs that leads to persistent Tel1- and Rad53-dependent DNA damage checkpoint activation and cell cycle arrest. Whether this enhanced checkpoint signaling contributes to the DNA damage sensitivity and/or the resection defect of sae2Δ cells is not known. By performing a genetic screen, we identify rad53 and tel1 mutant alleles that suppress both the DNA damage hypersensitivity and the resection defect of sae2Δ cells through an Sgs1-Dna2-dependent mechanism. These suppression events do not involve escaping the checkpoint-mediated cell cycle arrest. Rather, defective Rad53 or Tel1 signaling bypasses Sae2 function at DSBs by decreasing the amount of Rad9 bound at DSBs. As a consequence, reduced Rad9 association to DNA ends relieves inhibition of Sgs1-Dna2 activity, which can then compensate for the lack of Sae2 in DSB resection and DNA damage resistance. We propose that persistent Tel1 and Rad53 checkpoint signaling in cells lacking Sae2 increases the association of Rad9 at DSBs, which in turn inhibits DSB resection by limiting the activity of the Sgs1-Dna2 resection machinery.
Maternal Control of Integument Cell Elongation and Zygotic Control of Endosperm Growth Are Coordinated to Determine Seed Size in Arabidopsis

We use Arabidopsis thaliana as a model to investigate coordination of cell proliferation and cell elongation in the three components that develop side by side in the seed. Two of these, the embryo and its nurturing annex, the endosperm, are placed under zygotic control and develop within the seed integument placed under maternal control. We show that integument cell proliferation and endosperm growth are largely independent from each other. By contrast, prevention of cell elongation in the integument by the mutation transparent testa glabra2 (ttg2) restricts endosperm and seed growth. Conversely, endosperm growth controlled by the HAIKU (IKU) genetic pathway modulates integument cell elongation. Combinations of TTG2 defective seed integument with reduction of endosperm size by iku mutations identify integument cell elongation and endosperm growth as the primary regulators of seed size. Our results strongly suggest that a cross talk between maternal and zygotic controls represents the primary regulator of the coordinated control of seed size in Arabidopsis.
ROUTE OPTIMIZATION IN NESTED MOBILE NETWORKS (NEMO) USING OLSR

Internet edge mobility has been possible for a number of years: mobile IP[8], allows a host to change its point of at- tachment to the Internet and NEMO [6] allows the same functionality for a group of hosts along with a mobile router. The virtue of NEMO and mobile IP is transparency: a host remains identifiable through the same IP address, and traffic sent to that IP address will be tunneled to arrive at the intended node. NEMO allows "nested networks": a mobile network which attaches to another mobile network to arbitrary depth. However for each level of nesting, traffic is encap- sulated and tunneled to reach the destination. This leads to increased overhead (encapsulation) and to sub-optimal paths (tunneling without consideration for the actual net- work topology). In this paper, we investigate route-optimization in nested NEMO networks. We employ an ad-hoc routing protocol between mobile routers to ensure shortest routes when both source and destination for traffic is within the nested NEMO network. The mechanism also simplifies the requirements for route optimization when the source node is located outside of the nested NEMO network.
Memory management scheme for cost-effective disk-on-modules in consumer electronics devices

A disk-on-module (DOM) is a NAND flash memory-based device with legacy I/O interface which does not require any special device driver due to the presence of flash translation layer (FTL). FTL is an intermediate software layer which makes DOMs look like conventional hard disk drives. Since DOMs are usually used in mass-market consumer electronics devices, they are extremely cost sensitive; hence FTL should be able to run in a severely resource-constrained environment. In this paper, we propose TinyFTL, a new FTL which employs an efficient memory management scheme for DOMs with a very small amount of memory. TinyFTL divides the mapping information into multiple levels and caches only recently-accessed mapping information in memory. According to experimental evaluation, TinyFTL shows the performance comparable to or better than the existing FTLs with only 4.3- 6.2% of memory requirement (12 KB) for 16 GB NAND flash memory.
Discovery of Gas Accretion onto Stars in 13 Myr old h and χ Persei

We report the discovery of accretion disks associated with ~13 Myr old intermediate/low-mass stars in h and χ Persei. Optical spectroscopy of ~5000 stars in these clusters and a surrounding halo population reveal 32 A-K stars with Hα emission. Matching these stars with 2MASS and optical photometry yields 25 stars with the highest probability of cluster membership and EW(Hα) ≥ 5 Å. Sixteen of these sources have EW(Hα) ≥ 10 Å. The population of accreting sources is strongly spectral type dependent: Hα emission characteristic of accretion, especially strong accretion [EW(Hα) ≥ 10 Å], is much more prevalent around stars later than G0. Strong Hα emission from accretion is typically associated with redder Ks - [8] colors. The existence of accreting pre-main-sequence stars in h and χ Persei implies that circumstellar gas in some systems, especially those with primaries later than G5 spectral type, can last longer than 10-15 Myr.