Miracle-dz/UniFAR-FTUs huggingface dataset:
A sentiment-based filteration and data analysis framework for social media

This paper describes a framework that explains the processes involved in the filteration and analysis of data for user generated content in social media.Previous researches have put their focus in leveraging high quality data from social media data stream, but there are many opportunities that need to be explored.This paper proposes a sentiment-based filteration and data analysis framework in identifying relevant information from data generated by users in social media.Based on the textual contents generated and spread through social media, it is assumed that each of the set of text streams/corpora might carry a sentiment associated with it regardless of its polarity bias. Due to this, the proposed framework introduces the idea of data filtering that exploits information and sentiment captured in text while at the same time adapts text analysis methods overcoming the noisy and unstructured nature of social media textual content.
Overall cost in the treatment of otitis media.

BACKGROUND Numerous antimicrobial agents are available for treatment of otitis media (OM); however, little is known about the relative cost effectiveness of these drugs. METHODS We developed a noninvasive, observational model to assess the total costs (direct and indirect) associated with commonly used antibiotics in the therapy of OM. We also gathered data on recurrence rates, which can significantly affect costs. RESULTS The average total cost of treating an episode of OM in this study was $115.80. Treatment of a recurrent OM episode was significantly more costly than treatment of an initial episode ($124.64 vs. $107.81, P = 0.0001). This study suggests that significant costs are associated with OM treatment and that antibiotic price constitutes only a small portion of this cost. Recurrence rates appeared to vary with various antibiotic treatments. CONCLUSION We conclude that recurrence is a major determinant of OM treatment costs. Drugs associated with lower rates of recurrence will usually be the most cost-effective treatment options.
Dynamic Resource Allocation for Overload Avoidance and Green Cloud Computing

Cloud Computing is a flourishing technology because of its scalability, flexibility, availability of resources and other features. Resource multiplexing is done through the virtualization technology in cloud computing. Virtualization technology acts as a backbone for provisioning requirements of the cloud based solutions. At present, load balancing is one of the challenging issues in cloud computing environment. This issue arises due to massive consumer demands variety of services as per their dynamically changing requirements. So it becomes liability of cloud service provide to facilitate all the demanded services to the cloud consumers. However, due to the availability of finite resources, it is very challenging for cloud service providers to facilitate all the demanded services efficiently. From the cloud service provider’s perspective, cloud resources must be allocated in a fair manner. This paper addresses the existing techniques for resource allocation in cloud computing and proposes the dynamic resource allocation technique to mitigate overloads. It also focuses on energy consumption issue of cloud data centres and devised technique for lower energy consumption in order to achieve green cloud computing.
Relación de género, curso y tipo de colegio con el clima motivacional percibido en la Educación Física escolar en estudiantes colombianos Relationship of gender, grade and school type to the perceived motivational climate in school Physical Education among Colombian students

Motivational climate during Physical Education classes may be relevant for the adoption of active and healthy lifestyles, as well as for the learning progression and for the curricular development of Physical Education itself. This study was aimed to analyze the influence of different variables on the perceived motivational climate during Physical Education classes in a sample of Colombian students, using Spanish adaptations of the Perceived Motivational Climate in Physical Education Classes Questionnaire (PCSMQ-2) and the Learning and Performance Oriented Physical Education Classes Questionnaire (LAPOPECQ). A total of 3,149 students participated (1,455 boys and 1,694 girls), with ages between 9 and 19 years, and coming from three public and three private schools from the metropolitan zone of the municipality of Bucaranga, in Colombia.Results of factor analysis and measurement of Cronbach alpha coefficients confirm the validity and reliability of the two questionnaires and indicate that both instruments allow to measure equivalent dimensions of the motivational climate in the classes of Physical Education. Our investigation has shown, using a sample different from the habitual coming from developed countries, that gender,grade and type of school are modulator variables of the perceived motivational climate. Part of the obtained results could be interpreted considering the existence of cultural factors as far as the type of learning climate in which Physical Education is developed.
On Matroids of Branch-Width Three

For all positive integers k, the class Bk of matroids of branch-width at most k is minor-closed. When k is 1 or 2, the class Bk is, respectively, the class of direct sums of loops and coloops, and the class of direct sums of series-parallel networks. B3 is a much richer class as it contains infinite antichains of matroids and is thus not well-quasi-ordered under the minor order. In this paper, it is shown that, like B1 and B2, the class B3 can be characterized by a finite list of excluded minors.
Cortactin and Crk cooperate to trigger actin polymerization during Shigella invasion of epithelial cells

Shigella, the causative agent of bacillary dysentery, invades epithelial cells in a process involving Src tyrosine kinase signaling. Cortactin, a ubiquitous actin-binding protein present in structures of dynamic actin assembly, is the major protein tyrosine phosphorylated during Shigella invasion. Here, we report that RNA interference silencing of cortactin expression, as does Src inhibition in cells expressing kinase-inactive Src, interferes with actin polymerization required for the formation of cellular extensions engulfing the bacteria. Shigella invasion induced the recruitment of cortactin at plasma membranes in a tyrosine phosphorylation–dependent manner. Overexpression of wild-type forms of cortactin or the adaptor protein Crk favored Shigella uptake, and Arp2/3 binding–deficient cortactin derivatives or an Src homology 2 domain Crk mutant interfered with bacterial-induced actin foci formation. Crk was shown to directly interact with tyrosine-phosphorylated cortactin and to condition cortactin-dependent actin polymerization required for Shigella uptake. These results point at a major role for a Crk–cortactin complex in actin polymerization downstream of tyrosine kinase signaling.
GENERIC ENZYMATIC RATE EQUATION UNDER LIVING CONDITIONS

Based on our experience in kinetic modeling of coupled multiple metabolic pathways, we propose a generic rate equation for the dynamical modeling of metabolic kinetics. It is symmetric for forward and backward reactions. Its Michaelis-Menten-King-Altman form makes the kinetic parameters (or functions) easy to relate to experimental values in the database and to use in computation. In addition, such a uniform form is ready to arbitrary number of substrates and products with different stiochiometry. We explicitly show how to obtain such rate equations rigorously for three well-known binding mechanisms. Hence, the proposed rate equation is formally exact under the quasi-steady state condition. Various features of this generic rate equation are discussed. In particular, for irreversible reactions, the product inhibition which directly arises from enzymatic reaction is eliminated in a natural way. We also discuss how to include the effects of modifiers and cooperativity.
Survival benefit of chemotherapy in metastatic colorectal cancer: a meta-analysis of randomized controlled trials

To estimate the magnitude of benefit of chemotherapy in prolonging survival for patients with metastatic colorectal cancer, a meta-analysis of randomized controlled trial was performed. A systematic search was performed to identify randomized trials comparing chemotherapy with observation or supportive care alone. Trials were assessed for quality of reporting, publication bias and heterogeneity. Relative risks for outcomes from published data were pooled using a random-effects model. Seven trials with 614 patients were included. All trials used fluoropyrimidine-based chemotherapy, through a variety of routes and schedules, including intravenous, intra-portal and hepatic arterial infusion. Compared with the ‘no-chemotherapy’ arm, chemotherapy significantly reduced 1-year mortality (risk ratio 0.69; 95% confidence interval (CI) 0.60–0.81, P< 0.00001). The mortality at 2 years was not significantly different (risk ratio 0.93; 95% CI 0.87–1.00, P = 0.053). Between-trial comparisons demonstrated benefit with a variety of routes and schedules. Chemotherapy significantly prolongs 1-year survival for patients with metastatic colorectal cancer, and should be offered to those with good performance status. © 2000 Cancer Research Campaign
Assisting Tourists on the Move- An Evaluation of Mobile Tourist Guides

The penetration of high-end mobile devices equipped with GPS and enhanced with multimedia features together with decreasing mobile data prices have resulted in larger usage of mobile services. One of the application domains particularly well-suited for mobile services is tourism, not least since tourists can be assisted especially during the vacation itself. Currently, there is a proliferation of such mobile tourist guides, proposing an unmanageable number of diverse functionalities. To counteract this situation, the contribution of this paper is threefold. First, an evaluation framework is proposed, comprising both, a classification of mobile tourist services and a categorization of their delivery aspects in terms of several orthogonal dimensions. Second, on basis of this framework, four representative mobile tourist guides are evaluated, thereby demonstrating the frameworks' applicability. Third, several lessons learned are discussed, thereby shedding light on the current state of effort in the area of mobile tourist guides.
Paradoxical Symptomatic Air Embolism after Saline Contrast Transesophageal Echocardiography

We read, with great interest, the recently published case report of paradoxical air embolism after air contrast transesophageal echocardiography (TEE). 1 The authors describe an interesting issue: a patient with suspected patent foramen ovale (PFO) may be at considerable risk of paradoxical embolism during injection of agitated saline. While the bubbles injected are small, their entrapment in the brain tissue could carry grave morbidity as in the reported patient. Furthermore, Belvis et al.2 conducted a prospective study of stroke patients undergoing TEE. They monitored the patients simultaneously with transcranial Doppler (TCD) and showed strong correlation between the number of microbubbles recorded by TEE and TCD. Their study confirms that microbubbles in the left atrium traverse in significant numbers to the brain. Therefore, it is only reasonable to believe that agitated saline injection in a patient with PFO could result in neurological symptoms. Microbubbles that traverse in microcirculation obstruct blood flow and cause ischemia in the surrounding tissue. Local damage is further extended by inflammation and complement activation.3 The elimination of microbubbles depends on several factors, such as gas composition, temperature, and pressure, and is not instantaneous. While this process takes place, local tissue damage occurs. Brain tissue is susceptible to interruption in blood flow and microbubbles injury, as was established in cardiac surgery.4 The clinical consequences of microbubbles in cerebral circulation range according to the extent of injury and the patient’s condition. Certainly, there is rarely a visible neurological deterioration, as described in the case report,1 because the bubbles are small. Fortunately, in most cases of agitated saline injection during TEE, there are no symptoms. The risk for paradoxical embolism following air contrast is well discussed, yet we are reluctant to agree with the authors’ recommendations as they appear in the last paragraph of the Discussion.1 Amongst others, they suggest that vigorously shaking the saline ensures minimal bubble size. This is inaccurate, bubbles in a liquid medium are in a dynamic process of uniting into large bubbles and separating into small bubbles.5 This persistent change continues in the blood. Thus, injecting smallsized bubbles can not guarantee small bubbles later, in the left atrium. Another suggestion was to administer inhaled oxygen to facilitate air bubble elimination. No experiment was carried out to prove that the administration of oxygen in ambient, “normal” pressure affect bubble elimination Hyperbaric oxygen therapy is considered to be the definitive treatment for cerebral air emboli.6,7 Indeed, the extent of injected air contrast should be limited in order to reduce the risk of cerebral microbubbles during transesophageal echocardiography.
Evaluation of a nurse-led falls prevention programme versus usual care: a randomized controlled trial.

OBJECTIVE to evaluate a nurse-led management plan and care pathway for older people discharged from an Accident and Emergency Department after a fall. DESIGN randomized controlled trial. SETTING a large teaching hospital. SUBJECTS 348 consecutive patients aged 65 or over attending the Accident and Emergency Department with a fall. INTERVENTIONS we randomized patients to falls nurse intervention or usual care. Within 4 weeks, the intervention group received a home assessment to address easily modifiable risk factors for falls. This included assessments of medication, ECG, blood pressure, cognition, visual acuity, hearing, vestibular dysfunction, balance, mobility, feet and footwear. All patients were given advice and education about general safety in the home. MAIN OUTCOME MEASURES Further falls, functional ability, re-attendance at the Accident and Emergency Department and admission to hospital. RESULTS at 6 months post-Index fall, 36 patients in the intervention group and 39 patients in the control group had had 89 and 145 falls respectively. Although the intervention group had less falls, this was not significant (P>0.05). Similarly, the intervention group had fewer fall-related admissions and bed days (8 and 69 respectively) than the control group (10 and 233 respectively). The intervention group scored significantly higher in indicators of function (P<0.05) and mobility within the community (P<0.02). CONCLUSIONS although the differences were not significant, patients in the intervention group had fewer falls, less hospital attendances and spent less time in hospital. Moreover, patients in the intervention group were more functionally independent at 6 months post-Index fall.
Immune Tolerance Negatively Regulates B Cells in Knock-In Mice Expressing Broadly Neutralizing HIV Antibody 4E10

A major goal of HIV research is to develop vaccines reproducibly eliciting broadly neutralizing Abs (bNAbs); however, this has proved to be challenging. One suggested explanation for this difficulty is that epitopes seen by bNAbs mimic self, leading to immune tolerance. We generated knock-in mice expressing bNAb 4E10, which recognizes the membrane proximal external region of gp41. Unlike b12 knock-in mice, described in the companion article (Ota et al. 2013. J. Immunol. 191: 3179–3185), 4E10HL mice were found to undergo profound negative selection of B cells, indicating that 4E10 is, to a physiologically significant extent, autoreactive. Negative selection occurred by various mechanisms, including receptor editing, clonal deletion, and receptor downregulation. Despite significant deletion, small amounts of IgM and IgG anti-gp41 were found in the sera of 4E10HL mice. On a Rag1−/− background, 4E10HL mice had virtually no serum Ig of any kind. These results are consistent with a model in which B cells with 4E10 specificity are counterselected, raising the question of how 4E10 was generated in the patient from whom it was isolated. This represents the second example of a membrane proximal external region–directed bNAb that is apparently autoreactive in a physiological setting. The relative conservation in HIV of the 4E10 epitope might reflect the fact that it is under less intense immunological selection as a result of B cell self-tolerance. The safety and desirability of targeting this epitope by a vaccine is discussed in light of the newly described bNAb 10E8.
Relational Parametricity and Separation Logic

Separation logic is a recent extension of Hoare logic for reasoning about programs with references to shared mutable data structures. In this paper, we provide a new interpretation of the logic for a programming language with higher types. Our interpretation is based on Reynolds's relational parametricity, and it provides a formal connection between separation logic and data abstraction.
On the effectiveness of accuracy of automated feature location technique

Automated feature location techniques have been proposed to extract program elements that are likely to be relevant to a given feature. A more accurate result is expected to enable developers to perform more accurate feature location. However, several experiments assessing traceability recovery have shown that analysts cannot utilize an accurate traceability matrix for their tasks. Because feature location deals with a certain type of traceability links, it is an important question whether the same phenomena are visible in feature location or not. To answer that question, we have conducted a controlled experiment. We have asked 20 subjects to locate features using lists of methods of which the accuracy is controlled artificially. The result differs from the traceability recovery experiments. Subjects given an accurate list would be able to locate a feature more accurately. However, subjects could not locate the complete implementation of features in 83% of tasks. Results show that the accuracy of automated feature location techniques is effective, but it might be insufficient for perfect feature location.
Studies on live rubella vaccine. V. Quantitative aspects of interference between rubella, measles and mumps viruses in their trivalent vaccine.

Rubella vaccine combined with measles and mumps vaccines was administered in a single injection to children of 1 to 5 years of age. All three vaccines were serologically effective, and the clinical reactions caused by measles vaccine were considerably alleviated, when 6 x 10(3) PFU of rubella and 10(4) TCD50 per dose of mumps vaccines were combined with 5 x 10(4) TCD50 of measles vaccine. When a larger amount of mumps vaccine (3 x 10(5) TCD50/dose) was used, it caused interference with the rubella and measles viruses, i.e., the antibody response to rubella virus became poor and the incidence of clinical reactions to measles virus decreased. On the other hand, when 5 x 10(5) TCD50/dose of measles vaccine was combined with 10(4) TCD50/dose of mumps vaccine, the clinical reactions to measles virus were decreased but were almost the same as those induced by this vaccine alone.
Precursor Lesions for Sporadic Pancreatic Cancer: PanIN, IPMN, and MCN

Pancreatic cancer is still a dismal disease. The high mortality rate is mainly caused by the lack of highly sensitive and specific diagnostic tools, and most of the patients are diagnosed in an advanced and incurable stage. Knowledge about precursor lesions for pancreatic cancer has grown significantly over the last decade, and nowadays we know that mainly three lesions (PanIN, and IPMN, MCN) are responsible for the development of pancreatic cancer. The early detection of these lesions is still challenging but provides the chance to cure patients before they might get an invasive pancreatic carcinoma. This paper focuses on PanIN, IPMN, and MCN lesions and reviews the current level of knowledge and clinical measures.
A Low-Noise 40-GS/s Continuous-Time Bandpass $\Delta\Sigma$ ADC Centered at 2 GHz for Direct Sampling Receivers

This paper presents a 40-GS/s continuous-time bandpass DeltaSigma analog-to-digital converter centered at 2 GHz for wireless base station applications. The ADC consists of a fourth-order loop with multiple feedback and is designed entirely in the s-domain. The circuit achieves an SNDR of 55 dB and 52 dB over bandwidths of 60 MHz and 120 MHz, respectively, and an SFDR of 61dB with a single-ended IIP3 of +4 dBm. The center frequency is tunable from 1.8 to 2 GHz. It employs a Gm-LCVAR filter based on a MOS-HBT cascode transconductor with an NFMIN of 2.29 dB. The entire circuit is implemented in a 130-nm SiGe BiCMOS technology with 150-GHz fT SiGe HBT and dissipates 1.6 W from a 2.5-V supply
Ferrocement water storage tanks

FERROCEMENT IS A form of thin concrete reinforced with layers of continuous and relatively small diameter mesh. It is usually made from a mortar of Portland cement and sand applied to steel reinforcement which is often provided in the form of small aperture wire mesh and/or closely spaced small diameter bars or wires. In conventional ferrocement this relatively close spacing of reinforcement throughout the mortar creates a composite material which behaves almost homogeneously; very differently to the way reinforced concrete behaves. However, many so called ‘ferrocement tanks’, although using small meshes, do not have reinforcement widely dispersed through the mortar, but they still function successfully. Although, perhaps, such tanks should strictly be referred to as ‘wire reinforced mortar tanks’, in this paper they will be included within the term ‘ferrocement tanks’. The aim of this paper is to publicise the advantages that ferrocement has over other materials commonly used for constructing water storage tanks. It also aims to give basic information on the different construction methods which can be used for ferrocement tanks. Further references are suggested for readers who want to examine some published tank designs and to experiment with using this material. Because of the lack of space , this paper has focused on cylindrical tanks. A hemispherical excavation lined with ferrocement and covered with a domed roof is one cost effective alternative (Nissen-Petersen 1992b). For smaller storage volumes jar shapes are appropriate.
Genome Sequence of Zymomonas mobilis subsp. mobilis NRRL B-1960

ABSTRACT Zymomonas mobilis subsp. mobilis is an efficient ethanol producer with application for industrial production of biofuel. To supplement existing Z. mobilis genomic resources and to facilitate genomic research, we used Oxford Nanopore and Illumina sequencing to assemble the complete genome of the beer spoilage isolate Z. mobilis subsp. mobilis strain NRRL B-1960.
Sub-Nano-Strain Multiplexed Fiber Optic Sensor Array for Quasi-Static Strain Measurement

This letter presents a high resolution multiplexed strain sensor for quasi-static strain measurement based on π-phase-shifted fiber Bragg gratings (π-PSFBGs). The sensor array is composed by four π-PSFBGs in parallel with different delay lines, and a time-division multiplexing scheme is proposed to interrogate the π-PSFBGs in turn. The Pound-Drever-Hall technique and the sideband interrogation method are employed to improve the resolution and the sampling rate. In the demonstrational experiment, three-channel quasi-static strain sensing is realized with a resolution better than 0.4 n and a sampling rate of 100 samples/s.