Miracle-dz/UniFAR-FTUs huggingface dataset:
Le sommeil des personnes atteintes de schizophrénie : résultats d'études par questionnaire, polysomnographie et analyse spectrale de l'EEG en sommeil paradoxal

Patients with schizophrenia may have an abnormal sleep even when clinically stable under pharmacological treatments. In the present thesis, sleep studies aim at measuring central nervous system dysfunctions that can be involved in the pathophysiology of schizophrenia. The present thesis includes three studies. These studies report results on sleep in patients with schizophrenia in a three levels analysis with three different groups of patients. The first level is subjective and describes sleep habits using a questionnaire administered to outpatients with schizophrenia clinically stable under pharmacological treatments. The second level of analysis is objective and evaluates sleep architecture using a meta-analysis of polysomnographic studies in untreated patients with schizophrenia. The third level is microstructural and uses electroencephalogram (EEG) spectral analysis to characterize REM sleep in never-treated patients with first-episode schizophrenia. The first study shows that, when evaluated using a sleep habits questionnaire, outpatients with schizophrenia clinically stable under pharmacological treatments report increased time to fall asleep, have earlier bedtime, later risetime, spend more time in bed and do more naps compared to healthy participants. Also, similarly to healthy participants, most patients with schizophrenia report normal wake time after sleep onset, are normally satisfied about their sleep and feel normally refreshed in the morning. The second study reveals that, objectively, when polysomnographic studies evaluating untreated patients with schizophrenia are submitted to a meta-analysis, patients with schizophrenia have increased sleep latency, reduced total sleep time, reduced sleep efficiency and increased wake time after sleep onset compared to healthy participants. Patients in acute drug withdrawal show more severe sleep disturbances in these variables compared to never treated patients. Only never treated patients show decreased stage 2 sleep duration compared to healthy participants. The meta-analysis does not reveal
Virtual-Switching-Aware VM Consolidation in Virtualized Data Centers

In virtualized data centers, live virtual machine (VM) migration can increase energy efficiency by consolidating VMs on fewer servers. This problem is usually considered as Bin Packing Problem with the server capacity constraints, such as CPU, memory and network bandwidth. In order to minimize the communication traffic in data center network, existing works proposed correlation-aware VM consolidation algorithms. VMs with high inter traffic will be consolidated as close as possible (e.g. Within a physical server). However, the traffic load of virtual switches causes a certain number of CPU cycles of physical servers to move traffic through virtual switches. This increases the risk that VMs running on servers are not allocated enough resource, and consequently reduces VMs' performance. In this work, we conduct experiments to estimate the server CPU overhead caused by virtual switching, and based on the experiment results, we propose virtual-switching-aware VM consolidation algorithm to solve this problem. Experiments on representative data center workloads show that the overhead can occupy 10% to 30% of server's CPU resources. Besides, our algorithm has a sharp decrease of the server capacity violation probability compared with the state-of-the-art baseline.
Developing Pragmatic Fluency in English as a Foreign Language: Routines and Metapragmatic Awareness

This study explores whether pragmatic fluency can best be acquired in the classroom by provision of input and opportunity for communicative practice alone, or whether learners profit more when additional explicit instruction in the use of conversational routines is provided. It is hypothesized that such instruction raises learners' awareness of the functions and contextual distributions of routines, enabling them to become more pragmatically fluent. Two versions of a communication course taught to advanced German learners of English for 14 weeks are examined, one version providing explicit metapragmatic information, the other withholding it. Samples of tape-recorded conversations at various stages of the courses are used to assess how students' pragmatic fluency developed and whether and how the development of fluency benefits from metapragmatic awareness.
Blocking Single-Stranded Transferred DNA Conversion to Double-Stranded Intermediates by Overexpression of Yeast DNA REPLICATION FACTOR A1

Double-stranded intermediates play a significant role in the process of Agrobacterium T-DNA integration into the host genome. Agrobacterium tumefaciens delivers its single-stranded transferred DNA (T-strand) into the host cell nucleus, where it can be converted into double-stranded molecules. Various studies have revealed that double-stranded transfer DNA (T-DNA) intermediates can serve as substrates by as yet uncharacterized integration machinery. Nevertheless, the possibility that T-strands are themselves substrates for integration cannot be ruled out. We attempted to block the conversion of T-strands into double-stranded intermediates prior to integration in order to further investigate the route taken by T-DNA molecules on their way to integration. Transgenic tobacco (Nicotiana benthamiana) plants that overexpress three yeast (Saccharomyces cerevisiae) protein subunits of DNA REPLICATION FACTOR A (RFA) were produced. In yeast, these subunits (RFA1–RFA3) function as a complex that can bind single-stranded DNA molecules, promoting the repair of genomic double strand breaks. Overexpression of the RFA complex in tobacco resulted in decreased T-DNA expression, as determined by infection with A. tumefaciens cells carrying the β-glucuronidase intron reporter gene. Gene expression was not blocked when the reporter gene was delivered by microbombardment. Enhanced green fluorescent protein-assisted localization studies indicated that the three-protein complex was predominantly nuclear, thus indicating its function within the plant cell nucleus, possibly by binding naked T-strands and blocking their conversion into double-stranded intermediates. This notion was further supported by the inhibitory effect of RFA expression on the cell-to-cell movement of Bean dwarf mosaic virus, a single-stranded DNA virus. The observation that RFA complex plants dramatically inhibited the transient expression level of T-DNA and only reduced T-DNA integration by 50% suggests that double-stranded T-DNA intermediates, as well as single-stranded T-DNA, play significant roles in the integration process.
Recovery from bereavement

In wondering the things that you should do, reading can be a new choice of you in making new things. It's always said that reading will always help you to overcome something to better. Yeah, recovery from bereavement is one that we always offer. Even we share again and again about the books, what's your conception? If you are one of the people love reading as a manner, you can find recovery from bereavement as your reading material.
Mental Illness and Juvenile Offenders

Within the past decade, reliance on the juvenile justice system to meet the needs of juvenile offenders with mental health concerns has increased. Due to this tendency, research has been conducted on the effectiveness of various intervention and treatment programs/approaches with varied success. Recent literature suggests that because of interrelated problems involved for youth in the juvenile justice system with mental health issues, a dynamic system of care that extends beyond mere treatment within the juvenile justice system is the most promising. The authors provide a brief overview of the extent to which delinquency and mental illness co-occur; why treatment for these individuals requires a system of care; intervention models; and the juvenile justice systems role in providing mental health services to delinquent youth. Current and future advancements and implications for practitioners are provided.
Influencing factors of consumer intention towards web group buying

In this paper, based on the technology acceptance model (TAM) we explore the influencing factors of consumer intention towards web group buying. We took back 224 questionnaires. The samples are students and staff in the company, who are the typical web group buying consumers. We use correlation analysis and regression analysis to analyze the questionnaire data and test the hypothesis model. The results show that perceived risk does not have a significant impact on customer intention; however, electronic Word-of-Mouth (eWOM) and discount would influence the intention through changing consumers' perceived usefulness and subjective norm.
Interfacial Stress Transfer in a Graphene Monolayer Nanocomposite

It is demonstrated from stress-induced Raman bands shifts that stress can be transferred from a polymer matrix to a graphene monolayer (see image) in a model nanocomposite. It is shown further that the behavior can be modeled using continuum mechanics and that the interface between the graphene and the polymer breaks down at a shear stress of the order of 2 MPa.
Sexual Salvation: Affirming Women's Sexual Rights and Pleasures

Foreword by Elizabeth Rice Allgeier Foreword by Albert Ellis Acknowledgments The Search for Sexual Salvation Lessons in Seduction Love and Intimacy Lesbian and Bisexual Identities Women Sex Trade Workers Sexual Victimization and Pornography Woman-Affirming Models of Sexual Fulfillment Sexual Rights and Pleasures in the Next Century Bibliography Index
A share strategy for utility frequent patterns mining

Frequent pattern mining and utility mining have been studied popularly. However, frequent pattern mining only mines frequent patterns without considering the different utility values of individual items and utility mining focuses on identifying the patterns with high utilities but no guarantee their frequencies. In this paper, we introduce a utility frequent pattern mining model based on a share strategy to find the combination of items with high frequencies and utilities. This model first find all patterns with a given minimum support threshold. In this step, a share strategy gives a way to share most of the results from the previous mining process instead of separating them distinctively, thereby dramatically reducing the cost of computation. And then all patterns that do not satisfy a user specified utility are pruned. The performance study shows that the share strategy is efficient for utility frequent patterns mining.
Enhancing banana weevil ( Cosmopolites sordidus ) resistance by plant genetic modification: A perspective

Banana weevil is a serious pest of bananas and plantains in Africa. The development of resistant cultivars is seen as the long term and more sustainable control strategy. The difficulty in conventional breeding of bananas and plantains has prompted efforts towards the use of genetic transformation for banana and plantain improvement. In this review, the current status of banana weevil resistance, sources of resistance and resistance mechanisms is assessed. Further, current efforts and future prospects for identifying resistance genes outside the genus Musa with potential to control banana weevil in a transgenic approach are outlined and discussed. Key words : Banana weevil, host plant resistance, pest resistance genes, transgenic plants African Journal of Biotechnology Vol. 2 (12), pp. 563-569, December 2003
Inhibition of the Human Liver Microsomal and Human Cytochrome P450 1A2 and 3A4 Metabolism of Estradiol by Deployment-Related and Other Chemicals

Cytochromes P450 (P450s) are major catalysts in the metabolism of xenobiotics and endogenous substrates such as estradiol (E2). It has previously been shown that E2 is predominantly metabolized in humans by CYP1A2 and CYP3A4 with 2-hydroxyestradiol (2-OHE2) the major metabolite. This study examines effects of deployment-related and other chemicals on E2 metabolism by human liver microsomes (HLM) and individual P450 isoforms. Kinetic studies using HLM, CYP3A4, and CYP1A2 showed similar affinities (Km) for E2 with respect to 2-OHE2 production. Vmax and CLint values for HLM are 0.32 nmol/min/mg protein and 7.5 μl/min/mg protein; those for CYP3A4 are 6.9 nmol/min/nmol P450 and 291 μl/min/nmol P450; and those for CYP1A2 are 17.4 nmol/min/nmol P450 and 633 μl/min/nmol P450. Phenotyped HLM use showed that individuals with high levels of CYP1A2 and CYP3A4 have the greatest potential to metabolize E2. Preincubation of HLM with a variety of chemicals, including those used in military deployments, resulted in varying levels of inhibition of E2 metabolism. The greatest inhibition was observed with organophosphorus compounds, including chlorpyrifos and fonofos, with up to 80% inhibition for 2-OHE2 production. Carbaryl, a carbamate pesticide, and naphthalene, a jet fuel component, inhibited ca. 40% of E2 metabolism. Preincubation of CYP1A2 with chlorpyrifos, fonofos, carbaryl, or naphthalene resulted in 96, 59, 84, and 87% inhibition of E2 metabolism, respectively. Preincubation of CYP3A4 with chlorpyrifos, fonofos, deltamethrin, or permethrin resulted in 94, 87, 58, and 37% inhibition of E2 metabolism. Chlorpyrifos inhibition of E2 metabolism is shown to be irreversible.
A Low Cost Grip Transducer Based Instrument To Quantify Fingertip Touch Force

In this paper, a transducer based instrument for fingertip touch force is developed. As a diagnostic tool, the system was coupled with an EMG analog signal processor, which is considered as the main basis of evaluation for motor function impairment. A software program is developed to analyze EMG signal during fingertips effort to obtain valid characteristic parameters with spectral analysis. These parameters are associated with a low cost grip transducer based on Hall Effect component developed for the improvement of fingertip movement during holding objects or training exercises. Thus, the changes on each sensor signal can be detected and monitored with the software interface. The output signal and the EMG analog processor are feeding a high resolution data acquisition system of National Instrument. Preliminary experimental tests have been carried out for the fingertip force grasping according to the adductor Pollicis muscle (AdP) for controlling the adductive motion of the thumb. The experimental results show that the changes of dynamic fingertip force affect the muscle.
A multifunctional bioactive material that stimulates osteogenesis and promotes the vascularization bone marrow stem cells and their resistance to bacterial infection

The main limitation of tissue engineering lies in the inability to stimulate osteogenesis, angiogenesis of stem cells and broad-spectrum antimicrobial activity. However, the development of multifunctional bioactive materials with these capabilities remains a great challenge. In this study, we prepared mesoporous silica nanoparticles encapsulated with silver nanocrystals (AG-MSN) with uniform sphere size and mesopores. Platelet-derived growth factor BB (PDGF-BB) was effectively loaded in the AG-MSN mesopores (P-AG-MSN). The silicon ions (Si) released by P-AG-MSN stimulate osteogenic differentiation of bone marrow stromal cells (BMSC) by activating the alkaline phosphatase (ALP) activity of bone-related genes and increasing protein (OCN, RUNX2 and OPN) expression. Ag+ ions could be slowly released from the interior of the shell, highlighting their durable antibacterial activity. The sustained release of PDGF-BB from P-AG-MSN stimulated the angiogenic differentiation of BMSC, as indicated by the enhanced secretion of vascular endothelial growth factor (VEGF), HIF-1α, HGF and ANG-1 and protein expression. Our results show that P-AG-MSN can clearly promote BMSC osteostimulation and vascularization. This research serves as a preliminary study of the utilization of this multifunctional mixture to fabricate a new active biological scaffold that integrates BMSC osteostimulation, vascularization and bactericidal effects by 3D printing technology.
Abortion Knowledge and Experiences Among U.S. Servicewomen: A Qualitative Study

CONTEXT U.S. servicewomen have a higher rate of unintended pregnancy than civilian women, yet the military does not provide or cover abortion, except in limited circumstances. Servicewomen's experiences with abortion care have received little research attention. METHODS Twenty-one in-depth interviews with servicewomen who had had an abortion during active-duty service in the prior two years were conducted between January 2015 and July 2016. Women reported on their experiences accessing abortion, as well as their knowledge and opinions of the military's abortion policy. Data were analyzed thematically using inductive and deductive codes. RESULTS In regard to their pregnancy and abortion experiences, servicewomen cited concerns about confidentiality, stigma and negative effects on their career, which prevented half of participants from seeking care from the military. Of those who visited a military treatment facility during pregnancy, some reported feeling upset or abandoned by the lack of options counseling and referral. Women reported that the military's abortion policy had negative health and emotional consequences for servicewomen, and negative financial and logistical consequences for both servicewomen and the military. Most did not have accurate knowledge of the abortion policy. Upon learning the law, the majority believed that the military should provide and cover abortion; yet, servicewomen also expressed apprehension about the military's involvement in abortion care, because of concerns about privacy and negative effects on women's careers. CONCLUSIONS Policy recommendations to better meet the needs of servicewomen include wider dissemination of the military's abortion policy, establishing abortion referral and support guidelines, and improving confidentiality in military health services.
Does market experience eliminate market anomalies

This study examines individual behavior in two well-functioning marketplaces to investigate whether market experience eliminates the endowment effect. Field evidence from both markets suggests that individual behavior converges to the neoclassical prediction as market experience increases. In an experimental test of whether these observations are due to treatment (market experience) or selection (e.g., static preferences), I find that market experience plays a significant role in eliminating the endowment effect. I also find that these results are robust to institutional change and extend beyond the two marketplaces studied. Overall, this study provides strong evidence that market experience eliminates an important market anomaly.
Recursive blocked algorithms for solving triangular systems—Part I: one-sided and coupled Sylvester-type matrix equations

Triangular matrix equations appear naturally in estimating the condition numbers of matrix equations and different eigenspace computations, including block-diagonalization of matrices and matrix pairs and computation of functions of matrices. To solve a triangular matrix equation is also a major step in the classical Bartels--Stewart method for solving the standard continuous-time Sylvester equation (AX − XB = C). We present novel recursive blocked algorithms for solving one-sided triangular matrix equations, including the continuous-time Sylvester and Lyapunov equations, and a generalized coupled Sylvester equation. The main parts of the computations are performed as level-3 general matrix multiply and add (GEMM) operations. In contrast to explicit standard blocking techniques, our recursive approach leads to an automatic variable blocking that has the potential of matching the memory hierarchies of today's HPC systems. Different implementation issues are discussed, including when to terminate the recursion, the design of new optimized superscalar kernels for solving leaf-node triangular matrix equations efficiently, and how parallelism is utilized in our implementations. Uniprocessor and SMP parallel performance results of our recursive blocked algorithms and corresponding routines in the state-of-the-art libraries LAPACK and SLICOT are presented. The performance improvements of our recursive algorithms are remarkable, including 10-fold speedups compared to standard algorithms.
Listening between the notes: personality, listening context, and aesthetic chills in everyday music listening

Why do people get chills in response to music? Most people report feeling chills — experienced as goose bumps, shivers down the spine, or hair standing on end — at least sometimes when listening to music, but a small minority of people say they've never had this experience. Past work indicates that personality, experience, and engagement in music are partially responsible for individual differences in the experience of chills in response to music, but there is still significant variance in chills that is unexplained. In the present study, experience sampling methods were used to better understand the within-person variability in the experience of chills. Eighty-nine undergraduates completed surveys of Big Five personality traits and music preferences, habits, and experience. For one week, participants responded to multiple daily surveys asking about activities, emotions, and environment, with an emphasis on music listening and chills. Hierarchical linear modeling was used to estimate several models of the variability in chills. Several factors of music listening were examined as potential predictors of chills, including the location, involvement of friends, music choice, structural components of the music, purpose of music listening, and concurrent activities. Of these, music that had special meaning and music that was instrumental had significant main effects on the occurrence of chills, as did taking more music classes and scoring high in facets of neuroticism and openness to experience. In addition, neuroticism and openness facets significantly interacted with contextual aspects of music listening, such as music familiarity, paying close attention to the music, and listening on headphones. Directions for future theorizing are discussed.
UWB Pulse Generation and modulation for signal extraction from implantable devices

Ultra WideBand (UWB) communication systems have been undergoing tremendous developments over the recent past years. The areas of interests are industrial automation, identification for short range geolocational positioning systems and for extraction of signals from implants and wearable gadgets used in the bio-medical field. Such interests are the motivation of exploring this technology in terms of its utility in estimating the bit-error-rate (BER) various modulation techniques offer as performance indices. In this paper, a UWB pulse generator is designed and the performance of different modulation techniques utilizing the same pulse generator is presented. The results include frequency domain power spectral density estimates for gauging the power requirements and BER for highlighting its performance index for benchmarking purposes. The power spectral density of the different modulated streams is also compared to the Federal Communications Commission (FCC) mask to check the adherence to the FCC power emission regulations.