Miracle-dz/UniFAR-FTUs huggingface dataset:
“VAI JOGAR?” FATORES QUE INFLUENCIAM A PARTICIPAÇÃO DE ADOLESCENTES COM PARALISIA CEREBRAL NA EDUCAÇÃO FÍSICA ESCOLAR

O objetivo do estudo foi compreender fatores que influenciam a participação de adolescentes com paralisia cerebral (PC) na Educação Física Escolar. Dez adolescentes com PC foram entrevistados utilizando roteiro de entrevista semiestruturado, cujo conteúdo foi gravado, transcrito e submetido à Análise de Conteúdo. Três categorias e sete subcategorias emergiram dessa análise. Verificou-se que fatores ambientais (atitudinais e físicos) e pessoais influenciaram a participação. Especificamente, as atitudes de colegas, professores e monitores, bem como a disponibilidade de dispositivos de auxílio para marcha e a acessibilidade física da escola foram elementos importantes que impactaram, negativamente ou positivamente, a participação na Educação Física. Características pessoais, como medo de realizar as atividades e baixa ou alta percepção de autoeficácia, também influenciaram o engajamento dos adolescentes na Educação Física e devem ser consideradas por profissionais da Educação Física e reabilitação.
SAFE Software and FED Database to Uncover Protein-Protein Interactions using Gene Fusion Analysis

Domain Fusion Analysis takes advantage of the fact that certain proteins in a given proteome A, are found to have statistically significant similarity with two separate proteins in another proteome B. In other words, the result of a fusion event between two separate proteins in proteome B is a specific full-length protein in proteome A. In such a case, it can be safely concluded that the protein pair has a common biological function or even interacts physically. In this paper, we present the Fusion Events Database (FED), a database for the maintenance and retrieval of fusion data both in prokaryotic and eukaryotic organisms and the Software for the Analysis of Fusion Events (SAFE), a computational platform implemented for the automated detection, filtering and visualization of fusion events (both available at: Error! Hyperlink reference not valid.). Finally, we analyze the proteomes of three microorganisms using these tools in order to demonstrate their functionality.
Soluble Notch ligand and receptor peptides act antagonistically during angiogenesis.

AIMS Notch signalling is essential for blood vessel formation. During angiogenesis, the Notch ligand DLL4 on the leading tip cell activates Notch receptors on the adjacent stalk cells. DLL4-Notch signalling is impaired by the Notch ligand JAG1 in endothelial cells. The Delta/Serrate/Lag2 (DSL) domain of the Notch ligands binds to the EGF-like repeats 11-13 of the Notch receptor. This study aimed to elucidate how soluble proteins containing these short domains interfere with Notch signalling during angiogenesis. METHODS AND RESULTS Adenoviral vectors were generated to express the DSL domains of DLL1, DLL4, JAG1, and the Notch1 EGF-like repeats 11-13 fused to immunoglobulin-G heavy chain. These soluble ligand peptides inhibited Notch signalling in endothelial cells and this caused hyperbranching in cellular angiogenesis assays and in the neonatal mouse retina. The soluble Notch receptor peptides bound stronger to JAG1 than DLL4 ligands, resulting in increased signalling activity. This led to impaired tip cell formation and less vessel sprouting in the retina. CONCLUSION The minimal binding domains of Notch ligands are sufficient to interfere with Notch signalling. The corresponding soluble Notch1 EGF11-13 peptide binds stronger to inhibitory Notch ligands and thereby promotes Notch signalling in endothelial cells.
Electrochemical Degradation Mechanisms in Algan/gan Hemts

The last twenty years have witnessed numerous developments in the design and performance of GaN-based high electron mobility transistors (HEMTs). The unique combination of the high critical electric field of wide band gap materials and the existence of a high mobility two-dimensional electron gas (2DEG) allows AlGaN/GaN transistors to be one of the most promising candidates for high power and high frequency applications [1]. Nowadays, the most of the focus of the GaN-based device development has shifted from breaking performance records or designing new device structures to achieving a higher level of device reliability. Various degradation modes have been found to limit the device performance of AlGaN/GaN HEMTs. Unfortunately, there has not been been a consensus on the physical mechanisms nor a clear solution yet on how to overcome the device degradation without de-rating the devices [2][3][4]. The main goal of this talk is therefore to provide physical understanding of some of main degradation mechanisms and provide new approached to solve them. We have carried out systematic studies on the origin of permanent structural and electrical degradation in AlGaN/GaN HEMTs. Hydroxyl groups (OH-) from the environment and/or adsorbed water on the III-N surface are found to play an important role in the formation of surface pits during OFF-state electrical stress. The mechanism of this water-related structural degradation is explained by an electrochemical cell formed at the gate edge where gate metal, the III-N surface and the passivation layer meet (Fig. 1). In this electrochemical cell, the gate metal acts as the cathode which provides electrons to the water at the interface between the passivation layer and the AlGaN layer when the gate-to-drain diode is reversed biased. The AlGaN layer acts as the anode and is decomposed and subsequently anodically oxidized in the presence of holes and hydroxyl ions (OH-). The complete balanced electrochemical reaction is in fact a reduction-oxidation (redox) reaction between AlGaN and water: 2 2 3 2 3 2 2 x 1 x 3H N O x)Ga (1 O xAl O 3H N Ga 2Al + + − + = + − The relationship between permanent structural and electrical degradation in AlGaN/GaN HEMTs under OFF-state stress has also been studied. Specifically, we have found that the permanent decrease of the drain current is directly linked with the formation of surface pits. One potential mechanism could be that the surface pits decrease the average thickness of the AlGaN barrier, …
Deltr: Digital embryo lineage tree reconstructor

We present DELTR, an automated pipeline for the analysis of time-resolved light sheet fluorescence microscopy images of zebrafish embryogenesis. It comprises 3D nucleus segmentation using shape-regularized graph cuts, parallelized extraction of geometrical features, and cell tracking by means of combinatorial optimization. We also discuss the interactive visualization software used for validating the results, and describe our advances towards reconstructing the entire cell lineage tree of the zebrafish. Our method achieves ca. 96 % accuracy for cell nucleus detection and ca. 90 % accuracy for the association of nuclei across subsequent time steps.
Finnish Future: From eLearning to mLearning?

The first part of the article is based on a book “The Challenges of ICT in Finnish Education” (Sinko&Lehtinen, 1999). That book describes results of national research about ICT in Finnish education. The project was divided into five sub-projects: universities (two sub-reports) edited by Jarmo Viteli; kindergartens and institutions of general and vocational education edited by Liisa Huovinen with the assistance of many reporters; lifelong learning, edited by Irene Hein; digital learning materials, written by Pekka Lehtiö. This article, which is aimed at an international readership, is based on the material of the whole project. The second part is introduction about mLearning (mobilelearning). Finland has been called the “experimental laboratory of information society and mobile communication” and as such it provides an interesting test case for exploring the use of information and communications technologies in education. The first results of mlearning activities will be available at December 2000.
Cross Language Dependency Parsing using a Bilingual Lexicon

This paper proposes an approach to enhance dependency parsing in a language by using a translated treebank from another language. A simple statistical machine translation method, word-by-word decoding, where not a parallel corpus but a bilingual lexicon is necessary, is adopted for the treebank translation. Using an ensemble method, the key information extracted from word pairs with dependency relations in the translated text is effectively integrated into the parser for the target language. The proposed method is evaluated in English and Chinese treebanks. It is shown that a translated English treebank helps a Chinese parser obtain a state-of-the-art result.
Design-for-test strategies for analogue and mixed-signal integrated circuits

Recent advances in technology are leading to increases in the complexity and applications of analogue and mixed-signal integrated circuits. This trend has been accompanied by an increase in the complexity of associated test specifications. Furthermore, the use of functional and specification based test programs for the analogue circuitry is being questioned due to high implementation costs, the difficulties associated with quantifying the effectiveness of the tests and in many cases difficulties in accessing embedded analogue macros. In addition quality levels expected by integrated circuit (IC) users are increasing, with typical targets currently being better than 40 ppm defect levels. New test solutions are therefore required for these circuit types. Design-for-Test (DfT) strategies are well established for digital circuits, whilst for analogue and mixed signal circuits, few techniques have been proposed and implementation of custom approaches is rare. This paper presents a summary of a number of possible approaches for improving test access by increasing both controllability and observability of internal functional blocks in analogue and mixed-signal ICs, evaluating both their effectiveness and their impact on circuit performance.
Expansive Subdynamics

This paper provides a framework for studying the dynamics of commuting homeomorphisms. Let α be a continuous action of Zd on an infinite compact metric space. For each subspace V of Rd we introduce a notion of expansiveness for α along V , and show that there are nonexpansive subspaces in every dimension ≤ d − 1. For each k ≤ d the set Ek(α) of expansive kdimensional subspaces is open in the Grassmann manifold of all k-dimensional subspaces of Rd. Various dynamical properties of α are constant, or vary nicely, within a connected component of Ek(α), but change abruptly when passing from one expansive component to another. We give several examples of this sort of “phase transition,” including the topological and measure-theoretic directional entropies studied by Milnor, zeta functions, and dimension groups. For d = 2 we show that, except for one unresolved case, every open set of directions whose complement is nonempty can arise as an E1(α). The unresolved case is that of the complement of a single irrational direction. Algebraic examples using commuting automorphisms of compact abelian groups are an important source of phenomena, and we study several instances in detail. We conclude with a set of problems and research directions suggested by our analysis.
Policy, Poverty, and Student Achievement: An Exploration of the Impact of State Policies

This article explores the associations between the achievement of economically disadvantaged students and the presence of state policies that include student achievement in teacher evaluations. We looked at student achievement across all 50 states from 2007 through 2013. A simple comparison of states with and without the policy suggested that economically disadvantaged students had similar or slightly lower reading and lower math achievement in those states with the policy than in states without it. Once state context was considered, we found that states that included student achievement in teacher assessment policies had slightly higher reading achievement among economically disadvantaged students than they would have had otherwise. We found no similar impact on math achievement. This policy did not reduce the gaps in achievement between economically disadvantaged students and their more affluent peers. Combined, these findings indicate that including student achievement in teacher assessment models did not eliminate poverty-induced educational disparities in the system.
Dynamics of mobile coupled phase oscillators

We study the transient synchronization dynamics of locally coupled phase oscillators moving on a one-dimensional lattice. Analysis of spatial phase correlation shows that mobility speeds up relaxation of spatial modes and leads to faster synchronization. We show that when mobility becomes sufficiently high, it does not allow spatial modes to form and the population of oscillators behaves like a mean-field system. Estimating the relaxation timescale of the longest spatial mode and comparing it with systems with long-range coupling, we reveal how mobility effectively extends the interaction range. © 2013 American Physical Society.
Assessment Method for a Power Analysis to Identify Differentially Expressed Pathways

Gene expression data can provide a very rich source of information for elucidating the biological function on the pathway level if the experimental design considers the needs of the statistical analysis methods. The purpose of this paper is to provide a comparative analysis of statistical methods for detecting the differentially expression of pathways (DEP). In contrast to many other studies conducted so far, we use three novel simulation types, producing a more realistic correlation structure than previous simulation methods. This includes also the generation of surrogate data from two large-scale microarray experiments from prostate cancer and ALL. As a result from our comprehensive analysis of parameter configurations, we find that each method should only be applied if certain conditions of the data from a pathway are met. Further, we provide method-specific estimates for the optimal sample size for microarray experiments aiming to identify DEP in order to avoid an underpowered design. Our study highlights the sensitivity of the studied methods on the parameters of the system.
Relay selection in FSO systems with all-optical relaying over Gamma-Gamma turbulence channels

In this paper, we consider an all-optical multi-relay FSO system and investigate its outage performance over Gamma-Gamma atmospheric turbulence channels. To avoid strict synchronization requirements among relay nodes, we employ relay selection and use only the selected relay in the relaying phase. The outage probability results indicate that relay selection demonstrates significant improvements over the conventional scheme with all relays active.
Similar Handwritten Chinese Character Discrimination by Weakly Supervised Learning

Traditional approaches for handwritten Chinese character recognition suffer in classifying similar characters. In this paper, we propose to discriminate similar handwritten Chinese characters by using weakly supervised learning. Our approach learns a discriminative SVM for each similar pair which simultaneously localizes the discriminative region of similar character and makes the classification. For the first time, similar handwritten Chinese character recognition (SHCCR) is formulated as an optimization problem extended from SVM. We also propose a novel feature descriptor, Gradient Context, and apply bag-of-words model to represent regions with different scales. In our method, we do not need to select a sized-fixed sub-window to differentiate similar characters. The unconstrained property makes our method well adapted to high variance in the size and position of discriminative regions in similar handwritten Chinese characters. We evaluate our proposed approach over the CASIA Chinese character data set and the results show that our method outperforms the state of the art.
A Theory of Networks: In the Beginning . .

The geomorphic view of networking is a modular theory of contemporary networking, which is currently being developed. This paper presents the basic components and ideas of this theory in the form of a genesis story—what is needed to build the simplest possible network, and why other structures must be added as the network grows bigger and more complex. The story ends with the contemporary Internet, which is vastly more complex than what the classic Internet architecture describes. The paper also summarizes work on formalizing the theory and applying it to solve real problems.
Successive parallel interference canceller for asynchronous multirate DS-CDMA systems

The multi-code (MC) multirate DS-CDMA (direct sequence-code division multiple access) transmission system's performance is analyzed, associated to a multistage parallel interference cancellation (MPIC) structure, MC-MPIC, with hyperbolic tangent decision device in the intermediate stages. Extensive Monte Carlo simulations (MCS) considering total and partial cancellation in additive white Gaussian noise (AWGN) and flat Rayleigh channels indicated great performance gain of the MC-MPIC structure when compared to the conventional MC detection. The results show the feasibility of the proposed structure for future third generation (3G) systems.
Combining Sensorial Modalities in Haptic Navigation Tasks for Blind People

Recent development of haptic technology has made possible the physical interaction with virtual environments. The combination of sight, hearing and touch senses provides these virtual environments with enhanced realism perception and interactivity to simulate multiple real world tasks. Furthermore, the addition of the sense of touch can help in the design of specific virtual tasks for people with visual impairment. This paper analyses the advantages and drawbacks of combining tactile and sound stimuli to render virtual environments for blind people. Specifically, it studies the combination of both senses to provide navigation-related information in virtual tasks. A user study has been carried out among several subjects in order to discuss this issue. Results state that a combination of both senses provides better performance in navigation tasks than with only haptic feedback.
Efficient Speech Reinforcement Based on Low-Bit-Rate Speech Coding Parameters

In this paper, a novel approach to speech reinforcement in a low-bit-rate speech coder under ambient noise environments is proposed. The excitation vector of ambient noise is efficiently obtained at the near-end and then combined with the excitation signal of the far-end for a suitable reinforcement gain within the G.729 CS-ACELP Annex. B framework. For this reason, this can be clearly different from previous approaches in that the present approach does not require an additional arithmetic step such as the discrete Fourier transform (DFT). Experimental results indicate that the proposed method shows better performance than or at least comparable to conventional approaches with a lower computational burden.
The Cournot Model with Incomplete Information Based on the RDEU Theory

The classical Cournot model and the current model of oligopolistic competition have some serious defects which are inconsistent with the serious reality. These are complete information and rational player . Based on the RDEU theory, emotion function will be introduced to the game process. It constructs a RDEU-Cournot model with incomplete information . This model is capable to depict the relationship between the Nash equilibrium in the problem of duopolies game and the emotion preference of manufacturers. Moreover, the classical Cournot is a special case of it. On this basis, this paper obtains the Nash equilibrium of the RDEU-Cournot model, and the example of a Nash equilibrium dynamic evolution of modeling analysis.
Trajectory tracking for unicycle-type and two-steering-wheels mobile robots

Through two different approaches, this report proposes two general controllers for unicycle-type and two-steering-wheels mobile robots. For both systems, conditions for asymptotical convergence to a predefined path are established and simulation results are presented. Rather than writing the systems' equations with respect to a fixed reference frame, the robot state is here parametrized relative to the followed path, in terms of distance and orientation.
A robust ECO engine by resource-constraint-aware technology mapping and incremental routing optimization

ECO re-mapping is a key step in functional ECO tools. It implements a given patch function on a layout database with a limited spare cell resource. Previous ECO re-mapping algorithms are based on existing technology mappers. However, these mappers are not designed to consider the resource limitation and thus the corresponding ECO results are generally not good enough, or even become much worse when the spare cells are sparse. In this paper, we proposed a new solution for ECO remapping. It includes a robust resource-constraint-aware technology mapper and a fast incremental router for wire-length optimization. Moreover, we adopt a Pseudo-Boolean solver to search feasible solutions when the spare cells are sparse. Our experimental results show that our ECO engine can outperform the previous tool in both runtime and routing costs. We also demonstrate the robustness of our tool by performing ECOs on various spare cell limitations.
Posttranscriptional Gene Regulation by Spatial Rearrangement of the 3′ Untranslated Region

Translation termination at premature termination codons (PTCs) triggers degradation of the aberrant mRNA, but the mechanism by which a termination event is defined as premature is still unclear. Here we show that the physical distance between the termination codon and the poly(A)-binding protein PABPC1 is a crucial determinant for PTC recognition in human cells. “Normal” termination codons can trigger nonsense-mediated mRNA decay (NMD) when this distance is extended; and vice versa, NMD can be suppressed by folding the poly(A) tail into proximity of a PTC or by tethering of PABPC1 nearby a PTC, indicating an evolutionarily conserved function of PABPC1 in promoting correct translation termination and antagonizing activation of NMD. Most importantly, our results demonstrate that spatial rearrangements of the 3′ untranslated region can modulate the NMD pathway and thereby provide a novel mechanism for posttranscriptional gene regulation.