Miracle-dz/UniFAR-FTUs huggingface dataset:
Analysis on Awareness of Functional Dyspepsia and Rome Criteria Among Japanese Internists by the Self-administered Questionnaires

Background/Aims Functional dyspepsia (FD) is one of the commonest diseases in the field of Internal Medicine. The Japanese Society of Gastroenterology (JSGE) has been enlightening the term and concept of FD. Aim of this survey was to elucidate the understanding status of FD and Rome criteria and attitude toward FD among Japanese internists. Methods Data were collected at the time of lifelong education course for certified members of Japanese Society of Internal Medicine. Self-administered questionnaires were delivered to the medical doctors prior to the lectures. Results Analysis subjects were 1,623 (24-90 years old) internists among 1,660 medical doctors out of 4,264 attendees. The terms related to FD were known in 62.0-68.9% of internists, whereas 95.5% understood chronic gastritis. Internists who had been taking care of FD patients informed them as chronic gastritis (50.0%), FD in Japanese Kanji character (50.8%) and FD in Kanji and Katakana (18.6%). Logistic linear regression analysis revealed that positive factors for the understanding of FD and intensive care for FD patients were practitioner, caring many patients and certified physician by JSGE. Existence of Rome criteria was known in 39.9% of internists, and 31.8% out of them put it to practical use. The certified physician by JSGE was a positive factor for awareness, but not for utilization. Conclusions The results suggest the needs of enlightening the medical term FD in Japan and revision of Rome criteria for routine clinical practice. Precise recognition of FD may enhance efficient patient-based clinical practice.
Behavioral characteristics of elementary and secondary students with emotional/behavioral disabilities in four different cascade placements

The present investigation compared the characteristics of students with emotional/behavioral disabilities (EBD) in four sequential special education placements. Special education teachers in resource rooms, special classes, special schools, and residential schools rated the behavior of 473 elementary and secondary students in order to determine whether students' behavioral characteristics varied as a function of either placement or instructional level. RESULTS revealed differences in overall maladaptive behavior for some elementary, but no secondary placements. Elementary students had significantly higher rates of maladaptive behavior than secondary peers. Students in residential schools were more maladaptive than peers in either resource rooms or special classes. Implications for the reintegration and inclusion of students with EBD are discussed in light of the findings. Language: en
Création de valeur des TIC et banques de réseau : une contribution de la théorie de l'architecture organisationnelle

Cette these a pour but de mieux connaitre quelle est la contribution des technologies de l'information et de la communication (T. I. C. ) sur la creation de valeur des banques de reseau. Il s'agit de mettre en lumiere la place des T. I. C. Dans la coordination interne des banques en utilisant la theorie de l'architecture organisationnelle (A. O. ). Les T. I. C. Contribuent directement a la creation de valeur par l'utilisation pertinente qui est faite des outils. Les T. I. C. Contribuent indirectement a la creation de valeur par l'influence qu'ils peuvent avoir sur l'allocation des droits decisionnels ( qui entraine un mouvement de centralisation ou de decentralisation). La creation de valeur provient d'une mise en coherence des differentes composantes de l'A. O. Dans une premiere partie, nous procedons a une revue de litterature qui permet de definir les contours de l'investissement T. I. C. Une deuxieme partie developpe notre modelisation. Une troisieme partie presente les resultats empiriques.
Immunophenotypic evolution of blast populations in pediatric acute myeloid leukemia

Hospital Israelita Albert Einstein, Sao Paulo, SP, Brazil.Corresponding author: Welbert Oliveira Pereira – Avenida Albert Einstein, 627/701 − Morumbi − Zip code: 05652-900 − Sao Paulo, SP, Brazil − Phone: (55 11) 2151-3512 – E-mail: welbert.pereira@einstein.brReceived on: Sep 8, 2015 – Accepted on: Nov 4, 2015DOI: 10.1590/S1679-45082016AI3516
Porphyromonas gingivalis: a clonal pathogen?

Abstract The introduction of multilocus sequence typing (MLST) in infectious disease research has allowed standardized typing of bacterial clones. Through multiple markers around the genome, it is possible to determine the sequence type (ST) of bacterial isolates to establish the population structure of a species. For the periodontal pathogen, Porphyromonas gingivalis, the MLST scheme has been established at www.pubmlst. org/pgingivalis, and data from the database indicate a high degree of genetic diversity and a weakly clonal population structure comparable with Neisseria menigitidis. The major fimbriae (FimA) have been held responsible for the adhesive properties of P. gingivalis and represent an important virulence factor. The fimA genotyping method (PCR based) indicate that fimA genotype II, IV and Ib are associated with diseased sites in periodontitis and tissue specimens from cardiovascular disease. fimA genotyping of the isolates in the MLST database supports the association of genotypes II and IV with periodontitis. As a result of multiple positive PCR reactions in the fimA genotyping, sequencing of the fimA gene revealed only minor nucleotide variation between isolates of the same and different genotypes, suggesting that the method should be redesigned or re-evaluated. Results from several investigations indicate a higher intraindividual heterogeneity of P. gingivalis than found earlier. Detection of multiple STs from one site in several patients with “refractory” periodontitis, showed allelic variation in two housekeeping genes indicating recombination between different clones within the periodontal pocket.
Good genes, oxidative stress and condition–dependent sexual signals

The immune and the detoxication systems of animals are characterized by allelic polymorphisms, which underlie individual differences in ability to combat assaults from pathogens and toxic compounds. Previous studies have shown that females may improve offspring survival by selecting mates on the basis of sexual ornaments and signals that honestly reveal health. In many cases the expression of these ornaments appears to be particularly sensitive to oxidative stress. Activated immune and detoxication systems often generate oxidative stress by an extensive production of reactive metabolites and free radicals. Given that tolerance or resistance to toxic compounds and pathogens can be inherited, female choice should promote the evolution of male ornaments that reliably reveal the status of the bearer's level of oxidative stress. Hence, oxidative stress may be one important agent linking the expression of sexual ornaments to genetic variation in fitness–related traits, thus promoting the evolution of female mate choice and male sexual ornamentation, a controversial issue in evolutionary biology ever since Darwin.
A new approach to quantify reserve demand in systems with significant installed wind capacity

With wind power capacities increasing in many electricity systems across the world, operators are faced with new problems related to the uncertain nature of wind power. Foremost of these is the quantification and provision of system reserve. In this paper a new methodology is presented which quantifies the reserve needed on a system taking into account the uncertain nature of the wind power. Generator outage rates and load and wind power forecasts are taken into consideration when quantifying the amount of reserve needed. The reliability of the system is used as an objective measure to determine the effect of increasing wind power penetration. The methodology is applied to a model of the all Ireland electricity system, and results show that as wind power capacity increases, the system must increase the amount of reserve carried or face a measurable decrease in reliability.
Ethnic Background and Genetic Variation in the Evaluation of Cancer Risk: A Systematic Review

The clinical use of genetic variation in the evaluation of cancer risk is expanding, and thus understanding how determinants of cancer susceptibility identified in one population can be applied to another is of growing importance. However there is considerable debate on the relevance of ethnic background in clinical genetics, reflecting both the significance and complexity of genetic heritage. We address this via a systematic review of reported associations with cancer risk for 82 markers in 68 studies across six different cancer types, comparing association results between ethnic groups and examining linkage disequilibrium between risk alleles and nearby genetic loci. We find that the relevance of ethnic background depends on the question. If asked whether the association of variants with disease risk is conserved across ethnic boundaries, we find that the answer is yes, the majority of markers show insignificant variability in association with cancer risk across ethnic groups. However if the question is whether a significant association between a variant and cancer risk is likely to reproduce, the answer is no, most markers do not validate in an ethnic group other than the discovery cohort’s ancestry. This lack of reproducibility is not attributable to studies being inadequately populated due to low allele frequency in other ethnic groups. Instead, differences in local genomic structure between ethnic groups are associated with the strength of association with cancer risk and therefore confound interpretation of the implied physiologic association tracked by the disease allele. This suggest that a biological association for cancer risk alleles may be broadly consistent across ethnic boundaries, but reproduction of a clinical study in another ethnic group is uncommon, in part due to confounding genomic architecture. As clinical studies are increasingly performed globally this has important implications for how cancer risk stratifiers should be studied and employed.
Involvement of an Extracellular Glucan Sheath during Degradation of Populus Wood by Phanerochaete chrysosporium

Observations by transmission electron microscopy of wood samples of Populus tremula inoculated with the white rot fungus Phanerochaete chrysosporium showed that, at certain stages of their growth cycle, hyphae were encapsulated by a sheath which seems to play an active role in the wood cell wall degradation. Chemical and immunochemical techniques and 13C nuclear magnetic resonance spectroscopy were applied to demonstrate the β-1,3-1,6-d-glucan nature of the sheath. Double-staining methods revealed the interaction between the extracellular peroxidases involved in lignin degradation and the glucan mucilage. The glucan was also shown to establish a material junction between the fungus and the wood cell wall. It was concluded that, by means of these interactions, the sheath provides a transient junction between the hyphae and the wood, thus establishing a point of attachment to the site of the degradation. The association of peroxidases to the glucan matrix is in favor of the role of the sheath as a supporting structure. Furthermore, that the sheath was hydrolyzed during the attack demonstrated its active role both in providing the H2O2 necessary to the action of peroxidases and in providing a mode of transport of the fungal enzymes to their substrates at the surface of the wood cell wall.
Economic evaluation of a brief education, self-management and upper limb exercise training in people with rheumatoid arthritis (EXTRA) programme: a trial-based analysis.

OBJECTIVE The aim of this study was to conduct a cost-utility analysis of the Education, Self-management and Upper Limb Exercise Training in People with RA (EXTRA) programme compared with usual care. METHODS A within-trial incremental cost-utility analysis was conducted with 108 participants randomized to either the EXTRA programme (n = 52) or usual care (n = 56). A health care perspective was assumed for the primary analysis with a 36 week follow-up. Resource use information was collected on interventions, medication, primary and secondary care contacts, private health care and social care costs. Quality-adjusted life years (QALYs) were calculated from the EuroQol five-dimension three-level (EQ-5D-3L) questionnaire responses at baseline, 12 and 36 weeks. RESULTS Compared with usual care, total QALYs gained were higher in the EXTRA programme, leading to an increase of 0.0296 QALYs. The mean National Health Service (NHS) costs per participant were slightly higher in the EXTRA programme (by £82), resulting in an incremental cost-effectiveness ratio of £2770 per additional QALY gained. Thus the EXTRA programme was cost effective from an NHS perspective when assessed against the threshold of £20 000-£30 000/QALY gained. Overall, costs were lower in the EXTRA programme compared with usual care, suggesting it was the dominant treatment option from a societal perspective. At a willingness-to-pay of £20 000/QALY gained, there was a 65% probability that the EXTRA programme was the most cost-effective option. These results were robust to sensitivity analyses accounting for missing data, changing the cost perspective and removing cost outliers. CONCLUSION The physiotherapist-led EXTRA programme represents a cost-effective use of resources compared with usual care and leads to lower health care costs and work absence. TRIAL REGISTRATION International Standard Randomized Controlled Trial Number Register; http://www.controlled-trials.com/isrctn/ (ISRCTN14268051).
Subjective well-being one year after stroke

Objective: To compare the subjective well-being of stroke patients with that of a reference group, and to study its relationship to patient characteristics. Design: Cross-sectional study. Setting: Interviews performed in the respondents' homes, tests performed at the outpatient clinic. Subjects: Sixty patients one year after stroke (median age 74 years, interquartile range (IQR) 68-80), and 419 reference individuals (median age 75 years, IQR 71-80). Measures: Subjective well-being assessed with the General Health Questionnaire (GHQ-20). Explanatory variables were demographic and medical characteristics of the individuals and scores on validated tests: Barthel Index, Frenchay Activities Index (FAI), Sodring Motor Evaluation of Stroke Patients, Assessment of Cerebral Stroke and other Brain Damage, and Mini-Mental State Examination (MMSE). Results: A significantly higher proportion of the stroke patients than of the controls rated their subjective well-being as low, also after adjustment for age and gender (adjusted odds ratio 20.1, 95% confidence interval 9.6-42.0 by logistic regression). In bivariate analyses, leg and arm motor impairment, visuospatial impairment, apraxia, aphasia, low Barthel score, low FAI score, low MMSE score, and institutionalization were highly significant predictors of low subjective well-being (p-values <0.01). In multiple linear regression, a model with gender (p = 0.3) and upper extremity motor score (p <0.01 ) fitted the data well, and explained 48% of the variance in GHQ. Conclusion: Subjective well-being is decreased one year after stroke, and this is mainly attributed to arm motor impairments.
Low-Complexity CFO Compensation for Uplink OFDMA Systems

Orthogonal frequency-division multiplexing multiple access (OFDMA) has been considered as a promising multiple access technique in OFDM-based communication systems. In the system, all users share subcarriers in a frequency-division multiplexing manner. Similar to OFDM systems, the carrier frequency offset (CFO) induces inter-carrier interference (ICI) degrading the system performance seriously. However, since the CFO for each user may be different, the compensation turns out much more complicated than that in OFDM systems. A simple method to this problem is the use of a direct zero-forcing (ZF) method which involves the inverse of a matrix. The required computational complexity becomes prohibitively high when the number of subcarriers is large. In this paper, we propose a low-complexity method to overcome the problem in an interleaved uplink OFDMA system. We explore the special structure of the CFO-induced interference matrix and develop a method to solve the matrix inversion problem with fast Fourier transform (FFT). The proposed method can reduce the required computational complexity from O(Nc 3) to O(Nclog2Nc). From the simulations, we can see that the proposed method can perform as well as that of the direct ZF method while the required complexity is much lower
The Potential of Embedding Research Methods into Substantive Political Science Courses

Teaching research methods is an important part of most undergraduate political science curricula, though many programs do not have the capacity to require or offer the class for all of their majors. We examine whether it is possible to embed this knowledge into substantive courses to improve student understanding and knowledge of research methods issues. Using a quasi-experimental design in which test group students were exposed to low levels of research methods materials, we do not find that there is a statistically significant relationship between the means of correct answers between the preand post test, but we do find statistically significant change between the groups for certain items. We also discuss two unintended consequences of the experiment: depressed levels of efficacy about research methods materials and lower course ratings about readings by test group students.
The WebQuest as a Means of Enhancing Computer Efficacy.

This study examined the efficacy and outcomes expectancy of elementary preservice teachers related to using a WebQuest strategy to develop inquiry skills among elementary students. The findings of this study show that students in the experimental section of a group of preservice elementary teachers enrolled in a science methods course demonstrated a decrease in outcomes expectancy as measured on the MUTEBI instrument as compared to preservice teachers in a control group. Given that the preservice elementary education majors were in an experimental group that included actual classroom instruction with technology, concern arises with respect to having a nominally useful activity work against infusion of technology in the science classroom. Discussion from the author interprets the findings and offers thoughts for applying this in future teaching and clinical settings. (Author) Reproductions supplied by EDRS are the best that can be made from the original document. PERMISSION TO REPRODUCE AND DISSEMINATE THIS MATERIAL HAS BEEN GRANTED BY TO THE EDUCATIONAL RESOURCES INFORMATION CENTER (ERIC) U.S. DEPARTMENT OF EDUCATION Office of Educational Research and Improvement EDUCATIONAL RESOURCES INFORMATION CENTER (ERIC) Iii4liiiie-document has been reproduced as received from the person or organization originating it. 0 Minor changes have been made to improve reproduction quality. Points of view or opinions stated in this document do not necessarily represent official OERI position or policy. The WebQuest as a Means of Enhancing Computer Efficacy Kenneth P. King Department of Teaching and Learning Northern Illinois University DeKalb, IL 60115 W: 815-753-0384 F: 815-753-8594 kkingl@niu.edu 2 BEST COPY AVAILABLE Web Quest Investigation 2 Abstract This study examined the efficacy and outcomes expectancy of elementary preservice teachers related to using a Web Quest strategy to develop inquiry skills among elementary students. The findings of this study show that students in the experimental section of a group of preservice elementary teachers enrolled in a science methods course demonstrated a decrease in outcomes expectancy as measured on the MUTEBI instrument as compared to preservice teachers in a control group. Given that the preservice elementary education majors were in a experimental group that included actual classroom instruction with technology, concern arises with respect to having a nominally useful activity work against infusion of technology in the science classroom. Discussion from the author interprets the findings and offers thoughts for applying this in future teaching and clinical settings. WebQuest Investigation
Computational rim illumination with aerial robots

Lighting plays a major role in photography. Professional photographers use elaborate installations to light their subjects and achieve sophisticated styles. However, lighting moving subjects performing dynamic tasks presents significant challenges and requires expensive manual intervention. A skilled additional assistant might be needed to reposition lights as the subject changes pose or moves, and the extra logistics significantly raises costs and time. We present a new approach to lighting dynamic subjects where an aerial robot equipped with a portable light source lights the subject to automatically achieve a desired lighting effect. We focus on rim lighting, a particularly challenging effect to achieve with dynamic subjects, and allow the photographer to specify a required rim width. Our algorithm processes the images from the photographer's camera and provides necessary motion commands to the aerial robot to achieve the desired rim width in the resulting photographs. We demonstrate a control approach that localizes the aerial robot with reference to the subject and tracks the subject to achieve the necessary motion. Our proof-of-concept results demonstrate the utility of robots in computational lighting.
[Some risk factors in breast tumour etiology. Observations in Iaşi County between 2006 and 2010].

THE AIM OF STUDY To assess some risk factors and their involvement in female breast tumours etiology. MATERIAL AND METHODS The study was performed on a sample of 67 patients registered with breast tumours, at family phisicians' offices from Iasi, Romania. RESULTS Some risk factors were defined such as: nuliparity (20.8%) and first pregnancy after age 30 (34.3%); fibrous mastopathy in personal history (73.1% of cases with breast cancer) and breast cancer in siblings of first (8.9%) and second grade (11.9%). Relative to lifestyle, sedentary life was remarked in 59.2% of patients; modification of circadian rhythm in 28.3%, and excesive caffeine consumption in 80.9% of cases. CONCLUSIONS Further prevention and educational programs on breast tumoural risk factors are needed in Romania, even at female teenage, performed by family physician.
Scalable virtual machine storage using local disks

In virtualized data centers, storage systems have traditionally been treated as black boxes administered separately from the compute nodes. Direct-attached storage is often left unused, to not have VM availabilty depend on individual hosts. Our work aims to integrate storage and compute, addressing the fundamental limitations of contemporary centralized storage solutions. We are building Lithium, a distributed storage system designed specifically for virtualization workloads running in large-scale data centers and clouds. Lithium aims to be scalable, highly available, and compatible with commodity hardware and existing application software. The design of Lithium borrows techniques from Byzantine Fault Tolerance, stream processing, and distributed version control software, and demonstrates their practical applicability to the performance-sensitive task of virtual machine storage