Miracle-dz/UniFAR-FTUs huggingface dataset:
Critical Aspects for Mechanical Simulation in Dental Implantology

Dental implants have been widely used for the rehabilitation of completely and partially edentulous patients. (Branemark et al. 1969; Branemark et al. 1977; Adell et al. 1990; van Steenberghe et al. 1990) Despite the high success rates reported by a vast number of clinical studies, early or late implant failures are still unavoidable. (Esposito et al. 1998) Mechanical complications and failures have frequently been reported during prosthetic treatment. (Roberts 1970; Randow et al. 1986; Walton et al. 1986; Levine et al. 1999)
Resilient SARS-CoV-2 diagnostics workflows including viral heat inactivation

There is a worldwide need for reagents to perform SARS-CoV-2 detection. Some laboratories have implemented kit-free protocols, but many others do not have the capacity to develop these and/or perform manual processing. We provide multiple workflows for SARS-CoV-2 nucleic acid detection in clinical samples by comparing several commercially available RNA extraction methods: QIAamp Viral RNA Mini Kit (QIAgen), RNAdvance Blood/Viral (Beckman) and Mag-Bind Viral DNA/RNA 96 Kit (Omega Bio-tek). We also compared One-step RT-qPCR reagents: TaqMan Fast Virus 1-Step Master Mix (FastVirus, ThermoFisher Scientific), qPCRBIO Probe 1-Step Go Lo-ROX (PCR Biosystems) and Luna® Universal Probe One-Step RT-qPCR Kit (Luna, NEB). We used primer-probes that detect viral N (EUA CDC) and RdRP. RNA extraction methods provided similar results, with Beckman performing better with our primer-probe combinations. Luna proved most sensitive although overall the three reagents did not show significant differences. N detection was more reliable than that of RdRP, particularly in samples with low viral titres. Importantly, we demonstrated that heat treatment of nasopharyngeal swabs at 70°C for 10 or 30 min, or 90°C for 10 or 30 min (both original variant and B 1.1.7) inactivated SARS-CoV-2 employing plaque assays, and had minimal impact on the sensitivity of the qPCR in clinical samples. These findings make SARS-CoV-2 testing portable in settings that do not have CL-3 facilities. In summary, we provide several testing pipelines that can be easily implemented in other laboratories and have made all our protocols and SOPs freely available at https://osf.io/uebvj/.
Fwd: ApJ96041R2 Decision Letter

Supra–arcade downﬂows (SADs) are sunward, generally dark, plasma density depletions originated above posteruption ﬂare arcades. In this paper using 3D MHD simulations we investigate if the SAD cavities can be produced by a direct combination of the tearing mode and Kelvin–Helmholtz instabilities leading to a turbulent current sheet (CS) medium or if the current sheet is merely the background where SADs are produced triggered by an impulsive deposition of energy. We ﬁnd that to give account of the observational dark lane structures an addition of local energy, provided by a reconnection event, is required. We suggest that there may be a closed relation between characteristic SAD sizes and CS widths that must be satisﬁed to obtain an observable SAD
Asymptomatic or mild symptomatic SARS-CoV-2 infection elicits durable neutralizing antibody responses in children and adolescents

As SARS-CoV-2 continues to spread globally, questions have emerged regarding the strength and durability of immune responses in specific populations. In this study, we evaluated humoral immune responses in 69 children and adolescents with asymptomatic or mild symptomatic SARS-CoV-2 infection. We detected robust IgM, IgG, and IgA antibody responses to a broad array of SARS-CoV-2 antigens at the time of acute infection and 2 and 4 months after acute infection in all participants. Notably, these antibody responses were associated with virus-neutralizing activity that was still detectable 4 months after acute infection in 94% of children. Moreover, antibody responses and neutralizing activity in sera from children and adolescents were comparable or superior to those observed in sera from 24 adults with mild symptomatic infection. Taken together, these findings indicate that children and adolescents with mild or asymptomatic SARS-CoV-2 infection generate robust and durable humoral immune responses that can likely contribute to protection from reinfection.
Altitudinal segregation partially predicts survival of three alpine plant species across nunatak and peripheral glacial refugia

Survival of Quaternary cold stages in peripheral refugia and/or ice-free peaks within ice-sheets (nunataks) has likely (co)shaped the genetic structure of temperate mountain biota. We used three altitudinally segregated species endemic to the Dolomites and the adjacent Carnic Prealps in the southeastern European Alps to perform genetic structure analyses and demographic modeling based on RADseq data and retrospective species distribution models to test the following hypotheses. (i) The deep Piave valley forms the deepest genetic split in the species distributed across it. (ii) The montane to alpine species Campanula morettiana and Primula tyrolensis survived the Quaternary cold stages in peripheral refugia, while high-alpine to subnival Saxifraga facchinii likely survived in several nunatak refugia. (iii) The lower-elevation species suﬀered a strong population decline during the Quaternary glaciation. By contrast, the higher-elevation species shows long-term stability of population sizes due to survival on permanently ice-free peaks. We found peripheral refugia on both sides of the Piave Valley, which acted as a major genetic barrier. Demographic modeling conﬁrmed nunatak survival not only for S. facchinii, but also for C. morettiana; results were inconclusive for P. tyrolensis. Altitudinal segregation inﬂuenced the species’ demographic ﬂuctuations, with the lower-elevation species showing a signiﬁcant population increase at the end of the Quaternary cold stages, and the higher-elevation species either showing decrease towards the present or stable population sizes with a short bottleneck. Our results highlight the role of both nunatak survival and of species ecology in the demographic history of mountain species.
The Unique Challenges And Perspectives Of Telugu Jews In South India: Advocating For Greater Attention To Small And Overlooked Minority Communities

: This article provides an overview of the history and challenges faced by the Telugu Jewish community in India. The article highlights the diversity of India's cultural landscape and the challenges faced by minority communities, including the Jewish community, in preserving their cultural and religious identity. The article also introduces the Indian Jewish Heritage Centre, which was established in 2019 to showcase the history and culture of Indian Jews. The research design chosen for the study, which uses qualitative methods such as semi-structured interviews to explore the experiences and perspectives of Telugu Jews in South India. The article acknowledges the limitations of qualitative research and cautions against generalizing the findings to other Jewish communities in India or other minority communities facing similar challenges. The study identifies maintaining Jewish traditions and identity in a predominantly Hindu society as a key theme in the study. The article explains that the pressure to conform to the dominant culture can create difficulties in preserving religious practices and traditions critical to maintaining Jewish identity. The article also highlights the lack of access to Jewish resources, such as synagogues and religious texts, as a further challenge for Telugu Jews living in South India.Overall, the article provides valuable insights into the experiences of Telugu Jews in India and highlights the need for policies and programs aimed at promoting greater cultural diversity and social inclusion in India .
Analysis of Mode Choice Behavior in Greater Cairo Region

The paper analyzes individuals’ mode choice behavior in Greater Cairo Region (GCR) by calibrating a group of Multinomial Logit (MNL) mode choice models. Data used in the current work were collected through two surveys undretaken as a part of Cairo Regional Area Transportation Study (CREATS). These are: the Home Interview Survey (HIS) and the Revealed Preference Survey (RPS). Four mode choice models were calibrated; a general model, and three models for work, education and other trips. The analysis considered both socioeconomic and network variables. The socioeconomic variables included age, gender, and income. Network variables included travel time, travel fare, and out of vehicle time. An application exercise was carried out to predict the modal shifts in GCR under four hypothetical policy scenarios; increasing bus fare, increasing metro fare, increasing shared taxi fare and increasing individual income level. The results showed that the potential for mode shifts is minor even with drastic changes in network characteristics, therefore, mode choice in GCR is can be described as inelastic.
Industrial fluoride pollution of Jerbi grape leaves and the distribution of F,Ca, Mg, and P in them

SUMMARY: Fluoride damaged leaves of the Jerbi grape vine tree ( Vitis vinifera L) growing in the vicinity of a phosphate fertilizer manufacturing plant near Sfax, Tunisia, were used to study the distribution of the chemical elements F, Ca, Mg, and P in the leaves and stalks. Photosynthesis and the chlorophyll content of healthy leaf parts were also investigated to determine tolerance mechanisms of this species to fluoride. The subdivision of the necrotic zone into concentric necrotic halos evidently reflects a series of plant reactions to preserve a large portion of the leaf assimilatory surface. Photosynthesis still occurred with 30 to 40% necrosis of the leaves. Preferential accumulation of F was found in the leaf margins along with a parallel accumulation of Ca. Necrosis becomes evident when a fall in Ca occurs with an excess of F. After this happens, the plant tends to maintain high Mg and P concentrations in its healthy leaf parts. At 60% leaf necrosis, F seems to be effective in reducing photosynthesis and chlorophyll content.
of a text-independent speaker verification system by using feature combination and parallel structure

— Speaker Verification (SV) systems involve mainly two individual stages: feature extraction and classification. In this paper, we explore these two modules with the aim of improving the performance of a speaker verification system under noisy conditions. On the one hand, the choice of the most appropriate acoustic features is a crucial factor for performing robust speaker verification. The acoustic parameters used in the proposed system are: Mel Frequency Cepstral Coefficients (MFCC), their first and second derivatives (Deltas and Delta-Deltas), Bark Frequency Cepstral Coefficients (BFCC), Perceptual Linear Predictive (PLP), and Relative Spectral Transform - Perceptual Linear Predictive (RASTA-PLP). In this paper, a complete comparison of different combinations of the previous features is discussed. On the other hand, the major weakness of a conventional Support Vector Machine (SVM) classifier is the use of generic traditional kernel functions to compute the distances among data points. However, the kernel function of an SVM has great influence on its performance. In this work, we propose the combination of two SVM-based classifiers with different kernel functions: Linear kernel and Gaussian Radial Basis Function (RBF) kernel with a Logistic Regression (LR) classifier. The combination is carried out by means of a parallel structure approach, in which
Direct Estimation of the risk neutral factor dynamics of Gaussian term structure models

This paper proposes panel data tests of Gaussian a.ne term structure models. Yield curve data for di0erent moments in time are pooled with the factors treated as 1xed e0ects. With 1xed e0ects the time series properties of the price of risk can be ignored. Results of tests with US interest rate data show that the Gaussian model is able to capture the cross sectional structure of yields as well as unrestricted factor loadings from principal components analysis. However, estimates of the mean reversion parameters in a 3-factor model di0er signi1cantly when the model is estimated from yield levels or forward di0erences, which is inconsistent with the Gaussian model.
Identification of a novel and ancestral machinery involved in mitochondrial membrane branching in Trypanosoma brucei

African trypanosomes are eukaryotic parasites that exist in two main replicative forms; the procyclic form in the midgut of the insect vector, the tsetse fly Glossina spp. and the bloodstream form responsible for diseases in humans and cattle. Unlike most other eukaryotes, where mitochondria continuously fuse and divide, trypanosome mitochondria form a single and continuously interconnected network that only divides during cytokinesis. The machineries governing mitochondrial remodeling and interconnection, however, remain largely unknown. We characterize a dynamin-related protein (DRP) from T. brucei (TbDBF, previously called TbMfnL) that depicts sequence similarities with Opa1 and Mfn, mammalian DRPs involved mitochondrial fusion. We showed that TbDBF has closely related homologues in several organisms that are devoid of Mfn and Opa1, such as eukaryotes from different phyla, prokaryotes and archaea. TbDBF is the first member of this new protein family to be functionally characterized. It localizes to the mitochondrial periphery and, upon overexpression, induces a strong increase in the interconnection and branching of mitochondrial filaments in a GTPase dependent manner. Its overexpression also promotes a major increase in cellular and mitochondrial volume and an increased consumption of the two major carbon sources used by the parasite (glucose and proline), as well as ethanolamine, a precursor of phosphatidyl-ethanolamine involved in membrane biogenesis and shaping. We propose that mitochondrial TbDBF is a component of an ancestral membrane remodeling machinery that contributes to the formation of intermitochondrial connections.
Indium phosphide based membrane photodetector for optical interconnects on silicon

We have designed, fabricated and characterized an InP-based membrane photodetector on an SOI wafer containing a Si-wiring photonic circuit. New results on RF characterization up to 20 GHz are presented. The detector fabrication is compatible with wafer scale processing steps, guaranteeing compatibility towards future generation electronic IC processing.
Lifetime risk of maternal near miss: A novel indicator

The lifetime risk of maternal death is the risk that a 15-year-old girl will die of a maternal cause in her reproductive lifetime. Its intuitive appeal means it is a widely used summary measure for advocacy and international comparisons of maternal health. But relative to mortality, women are at a higher risk of experiencing life-threatening maternal morbidity called 'maternal near miss events' - complications so severe that women almost died. As maternal mortality continues to decline, stronger health indicators that include information on both fatal and non-fatal maternal outcomes are required. Thus, we propose a novel measure - the lifetime risk of maternal near miss - to estimate the risk a girl will experience at least one maternal near miss in her reproductive lifetime, accounting for survival from ages 15-49. This new indicator is urgently needed because existing measures of maternal morbidity prevalence (near miss ratio or rate) do not capture the cumulative risk over the reproductive life course. We use estimates of fertility and survival from the World Population Prospects for Kenya in 2021 along with simulated data on the maternal near miss ratio to demonstrate the calculation of the lifetime risk of maternal near miss. We estimate that the lifetime risk of maternal near miss in Kenya is 1 in 37, compared to a lifetime risk of maternal death of 1 in 59.
Basin Scale and Runoff Model Complexity

Many have contributed directly or indirectly to the research effort reported here. Special thanks to Dr. David A. Woolhiser. I am forever in his debt for his thoughtful guidance, gracious patience, and largess of time, insight and wisdom. Dr. Soroosh Sorooshian's acumen and discerning judgement has contributed greatly to this effort. Many staff members of the Aridland Watershed Management Research Unit of USDA -Agricultural Research Service (ARS), Tucson, Arizona have provided valuable knowledge, assistance and diligent collection of high quality hydrologic data. Special thanks are extended to Carl Unkrich, Tim Keefer, Roger Simanton and Fatima Lopez. Financial assistance during the course of my graduate work has been provided by the National Science Foundation via a Graduate Research Fellowship, the American Society of Civil Engineers and the Hydrology Section of the American Geophysical Union for a Research Fellowships, the U. S. Geological Survey, USDA - Agricultural Research Service, and the U. S. Department of Energy (Los Alamos National Laboratory). Preparation and distribution of this report was made possible by a NASA /EOS interdisciplinary investigation (Sorooshian and Huerte, 1989). Without this assistance this effort could not have been undertaken and I gratefully acknowledge this support.
6 Missing the Good Old Days: Investigating Outgroup Attitudes through Collective Nostalgia and Global Identification

A wooden toy from childhood, a song from an old movie or a retro hat we see in a storefront may get us to reminisce about the past. This bittersweet taste might make one feel sentimental or peaceful, while reimagining how good these old days were. Nostalgia refers to “a feeling of pleasure and also slight sadness when you think about things that happened in the past” (Cambridge University Press, n.d.). Research shows that nostalgia promotes a number of positive outcomes including social connectedness (Wildschut et al., 2010; Zhou et al., 2008), social support (Wildschut et al., 2010; Zhou et al., 2008), strong bonds with relatives (Abeyta et al., 2015; Wildschut et al., 2018), meaning in life (Routledge et al., 2011), belongingness and acceptance with the past generations (Abakoumkin et al., 2019; Sedikides et al., 2015, 2016) and approach motivation (Stephan et al., 2014). This individual feeling of missing the
Edinburgh Research Explorer Broadly speaking

One of the cardinal features of semantic dementia (SD) is a steady reduction in expressive vocabulary. We investigated the nature of this breakdown by assessing the psycholinguistic characteristics of words produced spontaneously by SD patients during an autobiographical memory interview. Speech was analysed with respect to frequency and imageability, and a recently-developed measure called semantic diversity. This measure quantifies the degree to which a word can be used in a broad range of different linguistic contexts. We used this measure in a formal exploration of the tendency for SD patients to replace specific terms with more vague and general words, on the assumption that more specific words are used in a more constrained set of contexts. Relative to healthy controls, patients were less likely to produce low-frequency, high-imageability words, and more likely to produce highly frequent, abstract words. These changes in the lexical-semantic landscape were related to semantic diversity: the highly frequent and abstract words most prevalent in the patients’ speech were also the most semantically diverse. In fact, when the speech samples of healthy controls were artificially engineered such that low semantic diversity words (e.g., garage, spanner) were replaced with broader terms (e.g., place, thing), the characteristics of their speech production came to closely resemble that of SD patients. A similar simulation in which low frequency words were replaced was less successful in replicating the patient data. These findings indicate systematic biases in the deterioration of lexical-semantic space in SD. As conceptual knowledge degrades, speech increasingly consists of general terms that can be applied in a broad range of linguistic contexts and convey less specific information.
to Estimate the Impact of Journal articles in

This article discusses the potential of Google Scholar ™ as an alternative or complement to the Web of Science and Scopus ™ for measuring the impact of journal articles in education. Three handbooks on research in science education, language education, and educational technology were used to identify a sample of 112 accomplished scholars. Google Scholar, Web of Science, and Scopus citations for 401 journal articles published by these authors during the five-year period 2003-2007 were then analyzed. The findings illustrate the promise and pitfalls of using Google Scholar for characterizing the influence of research output, particularly in terms of differences between the three sub-fields in publication practices. A calibration of the growth of Google Scholar citations is also provided.
Common Fixed Point Theorem for Weakly Compatible Mappings in Intuitionistic Fuzzy Metric Spaces

The present paper deals with a common fixed point theorem for weakly compatible mappings using condition of integral type in an intuitionistic fuzzy metric space. This result discovers the possibility of the idea of reciprocal continuity and weakly compatible maps to the problem of finding common fixed point of six mappings. Mathematics Subject Classification: 47H10, 54H25
and Beyond:

At the dawn of the twenty-first century, the world is awakened to a new series of phenomena and developments of far-reaching consequences. One of the most significant, in this regard, is the accelerated process of globalisation. While movements of goods and services, labour and capital , information and ideas, across national borders are not new; its acceleration in the last decade or so marks a qualitative break with the past. The process is also allpervasive. Not only the markets for goods, services, and capital are being globalised, the process also embraces such areas, like information, technology, socio-economic, politico-cultural and even moral spiritual institutions, ideas and values. No country, no region on earth, can remain outside the reach of the globalisation wave that is sweeping the world. As a consequence, the world today is more integrated than ever and the process of integration is accelerating further and further.
Linking specification to differentiation

Much of developmental biology is concerned with the processes by which cells become committed to particular fates in a regulated fashion, whereas cell biology addresses, among other things, the variety of differentiated forms and functions that cells can acquire. One open question is how the regulators of the former process lead to attainment of the latter. 'High-level' regulators of cell fate specification include the proneural factors, which drive cells to commit as precursors in the sensory nervous system. Recent research has concentrated on the gene expression events downstream of proneural factor function. Here we summarise this research and describe our own research that has provided clear links between a proneural factor, atonal, and the cell biological programme of ciliogenesis, which is a central aspect of sensory neuron differentiation.