Miracle-dz/UniFAR-FTUs huggingface dataset:
SRAM Interleaving Distance Selection With a Soft Error Failure Model

The significance of multiple cell upsets (MCUs) is revealed by sharing the soft-error test results in three major technologies, 90 nm, 65 nm, and 45 nm. The effectiveness of single-bit error correction (SEC) codes can be maximized in mitigating MCU errors when used together with the interleaving structure in memory designs. The model proposed in this paper provides failure probability to probabilistically demonstrate the benefits of various interleaving scheme selections for the memories with SEC. Grouped events such as MCU are taken into account in the proposed model by using the compound Poisson process. As a result of the proposed model, designers can perform predictive analysis of their design choices of interleaving schemes. The model successfully showed the difference in failure probability for different choices of interleaving schemes. The model behaved as the upper bound for failure probability when compared to the neutron test data with the 45-nm static-random-access memory (SRAM) design.
Course Update for Nurse Anesthetists Pathophysiology and Management of Angiotensin-Converting Enzyme Inhibitor – Associated Refractory Hypotension During the Perioperative Period

Objectives At the completion of this course, the reader should be able to: 1. Describe the factors that control short-term and long-term blood pressure regulation. 2. Identify the therapeutic effects and side effects of ACE inhibitors. 3. Understand the two types of hypotension associated with the preoperative use of ACE inhibitors. 4. Explain the pathophysiology of vasoplegic syndrome. 5. Discuss available treatment options for vasoplegic syndrome.
Successful use of rt-PA in pediatric stroke

There are no widely accepted guidelines for the use of recombinant tissue plasminogen activator (rt-PA) in children with acute stroke. We report a single case of rt-PA use in a 13-year-old girl with acute hemiplegia. She had a history of previous stroke, secondary to carotid dissection, and additional stroke risk factors. Treatment with IV rt-PA resulted in rapid clinical improvement. Our experience suggests that in selected pediatric patients with acute ischemic stroke rt-PA can be safely administered, and that this treatment option should be considered in children. A 13-year-old right-handed girl had a history of ischemic stroke secondary to internal carotid artery dissection. She presented with subacute onset of headache and sensory deficit in her left hand. On noncontrast head CT, an area of poor gray/white differentiation in the right parietal region and possible clot in the right middle cerebral artery (MCA) was seen. Angiography showed right internal carotid dissection; there was no evidence of fibromuscular dysplasia or other vascular irregularity. Several days earlier, while swimming, the patient had bumped her head on the pool bottom; she had also carried several friends on …
A Geometric Approach to Quantum Computation

A problem of particular interest in quantum computation is to find families of unitary operations that can be efficiently decomposed into elementary quantum gates. No previous methods have been able to solve this problem in the general case. Here we present a method using Riemannian geometry to determine such decompositions, as well as find an efficient circuit for them.
Alternatives to Bpref

Recently, a number of TREC tracks have adopted a retrieval effectiveness metric called bpref which has been designed for evaluation environments with incomplete relevance data. A graded-relevance version of this metric called rpref has also been proposed. However, we show that the application of Q-measure, normalised Discounted Cumulative Gain (nDCG) or Average Precision (AveP)to condensed lists, obtained by ? ltering out all unjudged documents from the original ranked lists, is actually a better solution to the incompleteness problem than bpref. Furthermore, we show that the use of graded relevance boosts the robustness of IR evaluation to incompleteness and therefore that Q-measure and nDCG based on condensed lists are the best choices. To this end, we use four graded-relevance test collections from NTCIR to compare ten different IR metrics in terms of system ranking stability and pairwise discriminative power.
A High-Isolation Dual-Polarization Patch Antenna With Omnidirectional Radiation Patterns

In this letter, a high-isolation dual-polarization microstrip patch antenna with omnidirectional radiation patterns is proposed. The radiation elements of the antenna are a combination of an annular-ring patch and four curved branches. The annular-ring patch is fed by a modified capacitive coupling structure to radiate a vertically polarized omnidirectional pattern, while the four curved branches that are set around the annular-ring patch with a suitable distance for high isolation are fed in phase to radiate a good horizontally polarized omnidirectonal radiation pattern. The isolation between the two ports is better than a high degree of - 40 dB to limit the interference of the signals. A prototype of the proposed antenna is fabricated and measured to verify the predictions, and the measured results are in good agreement with the simulated ones. The proposed antenna is a good candidate for wireless communication for its extremely low profile, high port isolation, and omnidirectional radiation property.
Protein phosphatase subunit G5PR is needed for inhibition of B cell receptor–induced apoptosis

B cell receptor (BCR) cross-linking induces B cell proliferation and sustains survival through the phosphorylation-dependent signals. We report that a loss of the protein phosphatase component G5PR increased the activation-induced cell death (AICD) and thus impaired B cell survival. G5PR associates with GANP, whose expression is up-regulated in mature B cells of the peripheral lymphoid organs. To study G5PR function, the G5pr gene was conditionally targeted with the CD19-Cre combination (G5pr−/− mice). The G5pr −/− mice had a decreased number of splenic B cells (60% of the controls). G5pr−/− B cells showed a normal proliferative response to lipopolysaccharide or anti-CD40 antibody stimulation but not to BCR cross-linking with or without IL-4 in vitro. G5pr−/− B cells did not show abnormalities in the BCR-mediated activation of Erks and NF-κB, cyclin D2 induction, or Akt activation. However, G5pr−/− B cells were sensitive to AICD caused by BCR cross-linking. This was associated with an increased depolarization of the mitochondrial membrane and the enhanced activation of c-Jun NH2-terminal protein kinase and Bim. These results suggest that G5PR is required for the BCR-mediated proliferation associated with the prevention of AICD in mature B cells.
Genome Sequence of Borrelia crocidurae Strain 03-02, a Clinical Isolate from Senegal

ABSTRACT The draft genome sequence of Borrelia crocidurae strain 03-02, a blood isolate from a febrile Senegalese patient, comprises a 920,021-bp linear chromosome (27.7% G+C content), 32 tRNAs, 818 open reading frames, and one cluster of regularly interspaced short palindromic repeats. Its genotype differs from that of the Achema reference strain.
Quasi-static Centralized Rate Allocation for Sensor Networks

Rate control for congestion mitigation and avoidance has received significant attention in the sensor networks literature. Existing rate control schemes dynamically assign rates in a distributed manner. In this paper, we take a step back and ask: is a near-optimal quasi-static centralized rate allocation even feasible for wireless sensor networks? Intuition would suggest otherwise, since wireless conditions vary dynamically, and optimal centralized rate allocation is known to be computationally intractable. Surprisingly, however, we find that, quasi-static centralized rate allocation performs well at time-scales of tens of minutes on a 40-node testbed. Our approach relies on a relatively simple, lightweight rate allocation heuristic that uses topology and loss rate information, and adapts at relatively long time-scales to channel variability. Extensive experiments on a 40-node wireless testbed show that sensor nodes achieve a goodput very close to their allocated rate, even in harsh wireless conditions. Furthermore, this achieved goodput is nearly 50% higher than that achieved by IFRC, a recently-proposed distributed rate control scheme, and within 13% of an empirically-determined optimal rate. We also evaluate extensions to our heuristic to support weighted fairness and networks with multiple base stations.
Data Mining Contributions to Characterize MV Consumers and to Improve the Suppliers-Consumers Settlements

This paper deals with the establishment of a characterization methodology of electric power profiles of medium voltage (MV) consumers. The characterization is supported on the data base knowledge discovery process (KDD). Data Mining techniques are used with the purpose of obtaining typical load profiles of MV customers and specific knowledge of their customers' consumption habits. In order to form the different customers' classes and to find a set of representative consumption patterns, a hierarchical clustering algorithm and a clustering ensemble combination approach (WEACS) are used. Taking into account the typical consumption profile of the class to which the customers belong, new tariff options were defined and new energy coefficients prices were proposed. Finally, and with the results obtained, the consequences that these will have in the interaction between customer and electric power suppliers are analyzed.
PEUT-ON RECOURIR A LA CORRUPTION DANS LES AFFAIRES ?

La corruption preoccupe de nombreux organismes publics ou prives qui aspirent a lutter contre ses ravages en impliquant l'entreprise. Elle constitue a la fois une menace et une opportunite pour l'entreprise. La question essentielle pour l'entreprise est des lors de savoir s'il est possible de gerer les risques induits par la corruption, plutot que d'appliquer un principe d'evitement systematique, ou de fermer les yeux sur certaines pratiques. Si l'idee qu'il existe une corruption acceptable est politiquement incorrecte, il convient neanmoins d'apprehender la realite de la corruption sur le terrain, pour permettre a l'entreprise de trouver des solutions equilibrees, a travers une methode appropriee de gestion des risques. Cet article prend en compte ce double aspect et demontre que la prise en compte de la corruption concerne a la fois les modes de gouvernance de l'entreprise, son fonctionnement operationnel, et doit s'inserer dans une strategie de gestion globale des risques.
Detection of Breast Cancer in Nipple Aspirate Fluid by CpG Island Hypermethylation

Purpose: New approaches to the early detection of breast cancer are urgently needed as there is more benefit to be realized from screening. Nipple aspiration is a noninvasive technique that yields fluid known to contain breast epithelial cells. Silencing of tumor suppressor genes such as p16INk4a, BRCA1, and hMLH1 have established hypermethylation as a common mechanism for tumor suppressor inactivation in human cancer and as a promising target for molecular detection. Experimental Design: Using sensitive methylation-specific PCR, we searched for aberrant promoter hypermethylation in a panel of six normally unmethylated genes: glutathione S-transferase π 1 (GSTP1); retinoic acid receptor-β2 (RARβ2); p16INk4a; p14ARF; RAS association domain family protein 1A (RASSF1A); and death-associated protein kinase (DAP-kinase) in 22 matched specimens of tumor, normal tissue, and nipple aspirate fluid collected from breast cancer patients. Results: Hypermethylation of one or more genes was found in all 22 tumor DNAs (100% diagnostic coverage) and identical gene hypermethylation detected in 18 of 22 (82%) matched aspirate fluid DNAs. In contrast, hypermethylation was absent in benign and normal breast tissue and nipple aspirate DNA from healthy women. Conclusions: Promoter hypermethylation of important cancer genes is common in breast cancer and could be detected in matched aspirate DNAs from patients with ductal carcinoma in situ or stage I cancer. Promoter hypermethylation represents a promising marker, and larger studies may lead to its useful application in breast cancer diagnosis and management.
DENSE GRAPHLET STATISTICS OF PROTEIN INTERACTION NETWORKS AND RANDOM NETWORKS

Understanding evolutionary dynamics from a systemic point of view crucially depends on knowledge about how evolution affects size and structure of the organisms’ functional building blocks (modules). It has been recently reported that statistics over sparse PPI graphlets can robustly monitor such evolutionary changes. However, there is abundant evidence that in PPI networks modules can be identified with highly interconnected (dense) and/or bipartite subgraphs. We count such dense graphlets in PPI networks by employing recently developed search strategies that render related inference problems tractable. We demonstrate that corresponding counting statistics differ significantly between prokaryotes and eukaryotes as well as between ”real” PPI networks and scale free network emulators. We also prove that another class of emulators, the low-dimensional geometric random graphs (GRGs) cannot contain a specific set of motifs, complete bipartite graphs, which are abundant in PPI networks.
ANALISIS PENGARUH STRATEGI SERVICE RECOVERY YANG DILAKUKAN PERBANKAN TERHADAP KEPUASAN NASABAH DI KOTA SEMARANG

Sekalipun perusahaan telah berusaha melakukan yang terbaik dalam rangka memenuhi kebutuhan dan keinginan pelanggannya, seringkali kegagalan jasa (service failure) tetap saja terjadi. Menurut UU RI No 10 Tahun 1998 tanggal 10 November 1998 tentang perbankan, dapat disimpulkan bahwa usaha perbankan meliputi tiga kegiatan, yaitu menghimpun dana, menyalurkan dana dan memberikan jasa bank lainnya. Service recovery merupakan tindakan spesifik yang dilakukan untuk memastikan bahwa pelanggan mendapatkan tingkat pelayanan yang pantas setelah terjadi masalah-masalah dalam pelayanan secara normal. Se rvice recovery yang baik akan mendeteksi dan memecahkan masalah, mencegah kekecewaan dan didisain untuk mengakomodasi keluhan. Service recovery secara umum dapat diwujudkan dengan tiga cara pokok yaitu : distributive justice, procedural justice dan interactional justice. Kata Kunci : Strategi Service, Kepuasan
Self-reported discrimination and mental health status among African descendants, Mexican Americans, and other Latinos in the New Hampshire REACH 2010 Initiative: the added dimension of immigration.

OBJECTIVES We examined whether self-reported racial discrimination was associated with mental health status and whether this association varied with race/ethnicity or immigration status. METHODS We performed secondary analysis of a community intervention conducted in 2002 and 2003 for the New Hampshire Racial and Ethnic Approaches to Community Health 2010 Initiative, surveying African descendants, Mexican Americans, and other Latinos. We assessed mental health status with the Mental Component Summary (MCS12) of the Medical Outcomes Study Short Form 12, and measured discrimination with questions related to respondents' ability to achieve goals, discomfort/anger at treatment by others, and access to quality health care. RESULTS Self-reported discrimination was associated with a lower MCS12 score. Additionally, the strength of the association between self-reported health care discrimination and lower MCS12 score was strongest for African descendants, then Mexican Americans, then other Latinos. These patterns may be explained by differences in how long a respondent has lived in the United States. Furthermore, the association of health care discrimination with lower MCS12 was weaker for recent immigrants. CONCLUSIONS Discrimination may be an important predictor of poor mental health status among Black and Latino immigrants. Previous findings of decreasing mental health status as immigrants acculturate might partly be related to experiences with racial discrimination.
A Teoria da Computação e o Profissional de Informática

Discute-se neste trabalho a importância do dominio do conhecimento e da fluencia em assuntos teoricos e abstratos como parte da bagagem conceitual dos profissionais da area de Informatica. Apresenta-se um quadro panorâmico geral da area, tecendo-se comentarios sobre diversos assuntos teoricos de interesse, procurando-se correlaciona-los e mostrar a sua relevância para o exercicio competente da pratica profissional. Palavras-chave: informatica; Computacao; Teoria da Computacao; abstracoes; ciencia; tecnologia; fundamentos; pratica; aplicacao. Abstract This paper discusses the importance of mastering and having detailed domain of theoretical and abstract knowledge as a part of the conceptual background for professionals in the field of informatics. A broad landscape of this field is shown, a diversity of interesting theoretical subjects are commented and interrelated, and their relevance for a competent professional practice is emphasized. Keywords: informatics; Computation; Theory of Computation; abstraction; science; technology; foundations; practice; applications.
Alterations in Exocytosis Induced by Neuronal Ca2+Sensor-1 in Bovine Chromaffin Cells

A variety of Ca2+ binding proteins are known to play an integral role in catecholamine release from synapses as well as secretory cells, such as chromaffin cells. TheDrosophila protein frequenin and its mammalian homolog neuronal Ca2+ sensor-1 (NCS-1) belong to a family of Ca2+ sensors with EF hands that bind Ca2+ and then interact with other proteins. Frequenin/NCS-1 has been shown to enhance exocytotic activity in addition to altering Ca2+ channel regulation. To better understand how NCS-1 regulates stimulus–secretion coupling, bovine chromaffin cells were infected with Semliki Forest virus (SFV) vectors containing the rat NCS-1 gene. Cells were studied in the perforated whole-cell patch-clamp configuration. Membrane capacitance was monitored as an indicator of exocytosis–endocytosis. Exocytosis elicited by membrane depolarization was not significantly different between cells infected with SFV expressing green fluorescent protein (GFP) or GFP plus NCS-1, except that the overexpression of NCS-1 resulted in a faster rundown in exocytosis. When cells were stimulated with histamine, NCS-1 overexpression led to higher exocytosis, as well as [Ca2+]i elevation. Immunocytochemistry showed a similar distribution of NCS-1 and phosphatidylinositol 4-kinase β (PI4Kβ). NCS-1 and PI4Kβ coimmunoprecipitate, opening up the possibility that the two proteins directly interact. These results suggest that NCS-1 may regulate cellular activity through the modulation of the phosphatidylinositol signaling pathway.
Carbonic anhydrase and acid–base regulation in fish

SUMMARY Carbonic anhydrase (CA) is the zinc metalloenzyme that catalyses the reversible reactions of CO2 with water. CA plays a crucial role in systemic acid–base regulation in fish by providing acid–base equivalents for exchange with the environment. Unlike air-breathing vertebrates, which frequently utilize alterations of breathing (respiratory compensation) to regulate acid–base status, acid–base balance in fish relies almost entirely upon the direct exchange of acid–base equivalents with the environment (metabolic compensation). The gill is the critical site of metabolic compensation, with the kidney playing a supporting role. At the gill, cytosolic CA catalyses the hydration of CO2 to H+ and HCO3– for export to the water. In the kidney, cytosolic and membrane-bound CA isoforms have been implicated in HCO3– reabsorption and urine acidification. In this review, the CA isoforms that have been identified to date in fish will be discussed together with their tissue localizations and roles in systemic acid–base regulation.
The Dynamic Nature of Leisure Experience: An Application of Affect Control Theory

Leisure experiences are believed to be dynamic and to emerge through an interaction process. A lack of theoretically based research has kept leisure scholars from developing a systematic understanding of this process. Affect Control Theory provides one basis for understanding the emerging and dynamic nature of emotions experienced during recreation. We have adopted the theory and applied it to a behavioral setting where people interact with social and physical aspects of the environment. One hundred and eleven respondents were intercepted and surveyed on a multiple-use trail in an urban greenway. An analysis program developed by Heise (1991) INTERACT II was used to predict emotions based on respondents' evaluations of events they encountered on the trail. Examples are conveyed that suggest why and how emotions, as a part of a recreational trail experience, differ both within a respondent's experience and between respondents' experiences. Results suggest that Affect Control Theory has potential to help explain how an interaction process in recreation creates a dynamic experience.
PORPLE: An Extensible Optimizer for Portable Data Placement on GPU

GPU is often equipped with complex memory systems, including globalmemory, texture memory, shared memory, constant memory, and variouslevels of cache. Where to place the data is important for theperformance of a GPU program. However, the decision is difficult for aprogrammer to make because of architecture complexity and thesensitivity of suitable data placements to input and architecturechanges.This paper presents PORPLE, a portable data placement engine thatenables a new way to solve the data placement problem. PORPLE consistsof a mini specification language, a source-to-source compiler, and a runtime data placer. The language allows an easy description of amemory system; the compiler transforms a GPU program into a formamenable to runtime profiling and data placement; the placer, based onthe memory description and data access patterns, identifies on the flyappropriate placement schemes for data and places themaccordingly. PORPLE is distinctive in being adaptive to program inputsand architecture changes, being transparent to programmers (in mostcases), and being extensible to new memory architectures. Ourexperiments on three types of GPU systems show that PORPLE is able toconsistently find optimal or near-optimal placement despite the largedifferences among GPU architectures and program inputs, yielding up to2.08X (1.59X on average) speedups on a set of regular and irregularGPU benchmarks.
First Italian case of cyclosporiasis in an immunocompetent woman: local acquired infection.

Cyclospora cayetanensis is a coccidian agent of chronic diarrhea in humans with a worldwide distribution. We report the first documented case of acquired Cyclosporiasis in Italy. The patient was an immunocompetent woman with no recent history of travel outside the country. Microscopy detected Cyclospora oocysts in a feces sample. PCR detected the pathogen in a second sample, which had tested negative by microscopy. The patient was investigated to detect other microorganisms in feces, such as Salmonella spp. , Shigella spp, Campylobacter spp. , Yersinia spp, and enteroviruses: all were negative. All symptoms disappeared 72 h after the beginning of therapy.
Research Priorities in Sales Strategy and Performance

A set of research issues and questions concerning strategic aspects of the sales function is developed, using as a framework the following “best practices” from industry identified by the Chally Group (1998): (1) establishing a customer-centric culture; (2) market segmentation; (3) market adaptability; (4) information technology; (5) sales, service, and technical support systems; (6) customer feedback and satisfaction; and (7) selecting and developing sales personnel. The article highlights the potential for sales academicians who pursue these research topics to contribute substantively to the effectiveness and efficiency of the sales function in modern organizations.