Miracle-dz/UniFAR-FTUs huggingface dataset:
Utilisation des jeux vidéo dans les soins de réhabilitation des sujets souffrant de schizophrénie : revue de la littérature

Introduction : depuis quelques annees les jeux video et la realite virtuelle sont utilises par des professionnels de sante comme medias d’informations, de formation ou meme comme outils therapeutiques. Le but de cette revue de la litterature est de faire un point sur l’utilisation de ces technologies a but therapeutique aupres de patients souffrant de schizophrenie. Methode : une recherche de toutes les etudes portant sur l’utilisation des JV dans la prise en charge des sujets souffrant de schizophrenie a ete realisee en octobre 2016. Les articles ont ete recenses a partir des bases de donnees electroniques PubMed, PsycInfo et Scopus grâce a une equation de recherche incluant les Medical Subject Headings (MESH) suivants : « video games », « virtual reality » et « therapy, computer-assisted/methods », chacun associe a « schizophrenia » Resultats : Vingt-cinq publications correspondant aux criteres de recherche et dont le contenu avait un interet significatif ont ete incluses. Les dispositifs etudies pouvaient etre classes en fonction de leurs objectifs therapeutiques correspondant a des cibles de prise en charge de rehabilitation psychosociale : ‐ Amelioration de la symptomatologie residuelle ‐ Remediation cognitive ‐ Remediation de la cognition et des habiletes sociales ‐ Amelioration de l’adhesion therapeutique ‐ Accompagnement dans les activites de la vie quotidienne ‐ Aide a l’insertion professionnelle. Discussion : les dispositifs cites ne peuvent remplacer une prise en charge usuelle mais pourraient la completer. Cependant leur recours semble premature du fait du caractere extremement recent de ces technologies et de la recherche s’y rattachant. Par ailleurs force est de constater le manque de lien existant entre ces travaux en psychiatrie et des champs de recherche autres en particulier les game studies. Enfin il pourrait etre interessant de s’attacher a analyser plus precisement l’impact neuropsychologique des jeux commerciaux existants, qui pourraient potentiellement trouver une utilite dans ces prises en charge.
Unsupervised Classification of Functions using Dirichlet Process Mixtures of Gaussian

The machine is equipped with a device for cutting the sheet to shift from one roll to another; the cutting device comprises a stand (3) on which a turret (2) has been mounted, said turret bearing at least two parallel spindles (1), each linked to rotating driving means known in the art; the rotation of the turret simultaneously removes a full roll and brings an empty spindle to the coiling station. A carriage (5) capable of motion perpendicular to the spindle axis conveys cylinders to load the machine with sheets to be rolled. The carriage (5) of the machine comprises a cylinder (16) for measuring the tension at which the position of the approaching sheet (F) is approximately horizontal; a contact cylinder (14) in contact with the roll at the coiling station, which is placed underneath and more or less in a vertical line with the tension measuring cylinder (16); a cutting device (11) positioned between the tension measuring and contact cylinders (16, 14) respectively, upstream of the coiling point onto the spindle or the roll to be formed.
Comparison between cationic polymer and lipid in plasmidic DNA delivery to the cell nucleus

We investigated the cell association and intracellular pathway to the nucleus of complexes formed between DNA and cationic lipid DOTAP (lipoplexes) or cationic polymer polyethylenimine (polyplexes). Flow cytometry and confocal microscope analysis showed that lipoplexes presented higher affinity for cell membrane than polyplexes. Electron microscopy demonstrated that both types of complexes followed an endocytic pathway and were metabolized but did not enter the nucleus. However, by in situ PCR and FISH it was possible to show that the plasmid localized to the nuclei, indicating that DNA must be dissociated from the vectors to be delivered to the nucleus. Our results identify a different behaviour in the interaction of polyplexes and lipoplexes with the cell, indicating that a combination of advantageous properties of the two kinds of cationic molecules could further ameliorate efficiency of nonviral gene transfer vectors.
Moral Reasoning in Driving Behavior

Page e6 Driving has become stressful, dangerous, and demeaning. Drivers report being stressed out, threatened by each other, exhibit bad moods, terrorize their passengers, and often fantasize violent acts against other motorists or bicyclists.1-3 These serious issues indicate that there is a strong need for driving psychology and education that can help reverse this trend and change people’s driving habits. Drivers need to be taught the moral dimension of driving, which indicates the character we have as a driver.4,5 Research is needed to assess how drivers can be taught to assess their own driving personality as supportive or hostile, rational or impatient, calm or frustrated, error-free or making mistakes, and cooperative or opportunistic. There is a need for motorists to acknowledge that driving is a social activity that requires coordinated interactions.6
Approaching Effective Data Visualisation in a Research Setting

A general purpose, easy-to-use graphical visualisation tool has been developed to facilitate the display of experiment data, ft supports simultaneous or selective rendering of surfaces, graphs and animated traces in a virtual 3D environment. It can accept as many as 100,000 objects for animated replay, and allows for interactive control of viewing position, lighting and other display parameters. The viewer is thus well suited to scoping experiment results, visually debugging data processing algorithms, and presenting complex data. Its principal application is in the visualisation of surfaces and graphs in the entropy analysis of medical and industrial related time-series
Does microtargeting matter? Campaign contact strategies and young voters

ABSTRACT In recent elections, campaigns have based their contact decisions on individual microtargeted propensity scores generated using “Big Data” rather than the more traditional geographic-based contacting. Shifts in campaign strategy have implications for who is contacted and ultimately who participates in elections. As campaigns focus more of their outreach towards individuals who the data indicate are more likely to turn out and more likely to vote for their candidate, some groups may be systematically excluded from contact. We investigate this using voter files and survey data from the 2012 US elections to compare who the Republicans identified for campaign contact using microtargeted propensity scores and who would have been identified for contact if they used a strictly geographic-based approach. Our findings suggest that young people are much less likely to be designated for contact when campaigns rely on microtargeted data than older individuals, the latter of whom are more likely to be contacted under both geographic and microtargeting strategies.
Release of cAMP Gating by the α6β4 Integrin Stimulates Lamellae Formation and the Chemotactic Migration of Invasive Carcinoma Cells

The α6β4 integrin promotes carcinoma in-vasion by its activation of a phosphoinositide 3-OH (PI3-K) signaling pathway (Shaw, L.M., I. Rabinovitz, H.H.-F. Wang, A. Toker, and A.M. Mercurio. Cell. 91: 949–960). We demonstrate here using MDA-MB-435 breast carcinoma cells that α6β4 stimulates chemotactic migration, a key component of invasion, but that it has no influence on haptotaxis. Stimulation of chemotaxis by α6β4 expression was observed in response to either lysophosphatidic acid (LPA) or fibroblast conditioned medium. Moreover, the LPA-dependent formation of lamellae in these cells is dependent upon α6β4 expression. Both lamellae formation and chemotactic migration are inhibited or “gated” by cAMP and our results reveal that a critical function of α6β4 is to suppress the intracellular cAMP concentration by increasing the activity of a rolipram-sensitive, cAMP-specific phosphodiesterase (PDE). This PDE activity is essential for lamellae formation, chemotactic migration and invasion based on data obtained with PDE inhibitors. Although PI3-K and cAMP-specific PDE activities are both required to promote lamellae formation and chemotactic migration, our data indicate that they are components of distinct signaling pathways. The essence of our findings is that α6β4 stimulates the chemotactic migration of carcinoma cells through its ability to influence key signaling events that underlie this critical component of carcinoma invasion.
Regional modulation of BOLD MRI responses to human sensorimotor activation by transcranial direct current stimulation

Blood oxygenation level dependent (BOLD) MRI was used to monitor modulations of human sensorimotor activity by prior transcranial direct current stimulation (tDCS). Activation maps for a right hand sequential finger opposition task were obtained for six subjects before as well as 0–5 min and 15–20 min after a 5‐min period of 1 mA cathodal and, in a separate session, anodal tDCS of the left‐hemispheric motor cortex. Cathodal tDCS resulted in a global decrease of the mean number of activated pixels by 38% (P < 0.01) 0–5 min after stimulation, which reduced to 28% (P < 0.05) 15–20 min after stimulation. A region‐of‐interest analysis revealed a 57% decrease of activated pixels (P < 0.001) in the supplementary motor area, but no change in the hand area of the primary motor cortex. Anodal tDCS yielded a nonsignificant 5% increase of activated pixels with no regional differences. These findings support the view that reduced neuroaxonal excitability after cathodal tDCS causes reduced brain activity. However, rather than affecting the primary sensorimotor input of an active task, the process appears to dampen those responses that rely on cortico‐cortical connections and related processing. Magn Reson Med 45:196–201, 2001. © 2001 Wiley‐Liss, Inc.
Morphological Productivity and Phonological Transparency

With a few important exceptions, such as Berko (1958) and Derwing and Baker (1977), linguistic morphology has always been a descriptive science, content with investigating actually occurring words and extracting patterns from these. Consequently, it has suffered from a difficulty common to all descriptive endeavours, the fear of obscuring individual cases in abstracting to general principles. In turn, as a result of this deficiency, morphological theory has tended to expend its energy not on general patterns, but rather on single words: more thought has been devoted to the one English word sang than to most other topics. In an earlier paper, Aronoff and Schvaneveldt (1978) showed how an experimental technique borrowed from cognitive psychology, the Lexical Decision Task, could be used to investigate morphological patterns without focusing primary attention on single actually occurring words. The essence of the technique is to ask native speakers of a language (English in this case) whether certain stimuli are words of their language or not.
A unified study of contention-resolution schemes in optical packet-switched networks

This paper presents a comprehensive study of contention-resolution schemes in a multiwavelength optical packet-switched network. This investigation aims to provide a unified study of a network of optical routers, which include contention resolution in wavelength, time, and space dimensions. Specifically, we show: 1) how to accommodate all three dimensions of contention resolution in an integrated optical router; 2) how the performance of the three dimensions compare with one another; and 3) how various combinational schemes can be designed and how they perform. With the representative architectures and network topologies studied in this paper, the simulation experiment results capture the characteristics of different contention-resolution schemes, and they quantify the upper-bound average offered transmitter load for these schemes. The combinational contention resolution schemes are shown to effectively resolve packet contention and achieve good network performance under light to intermediate load.
Discussions on Implementing Iterative Hard Thresholding Algorithm

Compressive sensing is a potential technology for lossy image compression. With a given quality, we may represent an image with a few significant coefficients in the transform domain. When the number of the significant coefficients is much less than the number of the pixels, the assumption of sparse representation is satisfied. Based on the sparse modeling theories, an image could be sensed with a relatively simple hardware and reconstructed with a powerful computer. We are interested in how to implement the iterative hard thresholding algorithm. The formula is not complex, but the implementation is not straightforward when the image resolution is high. Therefore, the computation complexity and the memory consumptions are analyzed. With the analysis result and the implementation experiences, we discuss the issues that should be considered carefully when implementing the algorithm in this paper.
Traffic Measurement and Analysis of a Broadband Wireless Internet Access

The increasing broadband wireless Internet usage and the limited wireless resources require a careful network management and optimization of the wireless Internet Service Providers (ISPs). Unfortunately, those providers often just have statistics about the overall usage and limited knowledge about the detailed application distribution as well as the traffic char- acteristics. In this paper we present user and traffic characteristics measured at a broadband wireless Internet access. The results show that the applications change quickly but the general characteristics like packet size and TCP/UDP percentage have not changed during the last years. Index Terms—traffic measurements, traffic classification, home networks, BWA, WLAN
Bias and precision in visual analogue scales: a randomized controlled trial.

Various types of visual analogue scales (VAS) are used in epidemiologic and clinical research. This paper reports on a randomized controlled trial to investigate the effects of variations in the orientation and type of scale on bias and precision in cross-sectional and longitudinal analyses. This trial was included in the pilot study of the SU.VI. MAX (supplementation by antioxidant vitamins and minerals) prevention trial in France in 1994. Six types of VAS (simple, middle-marked, graphic rating, graduated, graduated-numbered, and numerical rating) and two orientations (horizontal and vertical) were used to measure three symptoms of ear, nose, and throat infection at 2-month intervals in 870 subjects. Differences between scales were analyzed by comparing variances (Levene's test) and means (variance-covariance analysis for repeated measures). Scale characteristics were shown to influence the proportion of zero and low values (i.e., there was a floor effect), but not mean scores. The precision of measurements varied cross-sectionally according to the type of scale, but no differences were observed in the precision of measurement of change over time. In conclusion, the characteristics of VAS seem to be important in cross-sectional studies, particularly when symptoms of low or high intensity are being measured. Researchers should try to reach a consensus on what type of VAS to use if studies are to be compared.
Striatal and extrastriatal microPET imaging of D2/D3 dopamine receptors in rat brain with [18F]fallypride and [18F]desmethoxyfallypride

In this study, we compared two different D2/3 receptor ligands, [18F]fallypride and [18F]desmethoxyfallypride ([18F]DMFP) with respect to the duration of the scan, visualization of extrastriatal receptors, and binding potentials (BPND) in the rat brain. In addition, we studied the feasibility of using these tracers following a period of awake tracer uptake, during which the animal may perform a behavioral task. Male Sprague–Dawley rats were imaged with [18F]fallypride and with [18F]DMFP in four different studies using microPET. All scans were performed under isoflurane anesthesia. The first (test) and second (retest) study were 150‐min baseline scans. No retest scans were performed with [18F]DMFP. A third study was a 60‐min awake uptake of radiotracer followed by a 90‐min scan. A fourth study was a 150‐min competition scan with haloperidol (0.2 mg/kg) administered via tail vein at 90‐min post‐[18F]fallypride injection and 60‐min post‐[18F]DMFP. For the test–retest studies, BPND was measured using both Logan noninvasive (LNI) method and the interval ratios (ITR) method. Cerebellum was used as a reference region. For the third study, the binding was measured only with the ITR method, and the results were compared to the baseline results. Studies showed that the average transient equilibrium time in the dorsal striatum (DSTR) was at 90 min for [18F]fallypride and 30 min for [18F]DMFP. The average BPND for [18F]fallypride was 14.4 in DSTR, 6.8 in ventral striatum (VSTR), 1.3 in substantia nigra/ventral tegmental area (SN/VTA), 1.4 in colliculi (COL), and 1.5 in central gray area. In the case of [18F]DMFP, the average BPND values were 2.2 in DSTR, 2.7 in VSTR, and 0.8 in SN/VTA. The haloperidol blockade showed detectable decrease in binding of both tracers in striatal regions with a faster displacement of [18F]DMFP. No significant changes in BPND of [18F]fallypride due to the initial awake state of the animal were found, whereas BPND of [18F]DMFP was significantly higher in the awake state compared to baseline. We were able to demonstrate that dynamic PET using MicroPET Inveon allows quantification of both striatal and extrastriatal [18F]fallypride binding in rats in vivo. Quantification of the striatal regions could be achieved with [18F]DMFP. Synapse 2011. © 2011 Wiley‐Liss, Inc.
It’s All in the Eyes: Subcortical and Cortical Activation during Grotesqueness Perception in Autism

Atypical face processing plays a key role in social interaction difficulties encountered by individuals with autism. In the current fMRI study, the Thatcher illusion was used to investigate several aspects of face processing in 20 young adults with high-functioning autism spectrum disorder (ASD) and 20 matched neurotypical controls. “Thatcherized” stimuli were modified at either the eyes or the mouth and participants discriminated between pairs of faces while cued to attend to either of these features in upright and inverted orientation. Behavioral data confirmed sensitivity to the illusion and intact configural processing in ASD. Directing attention towards the eyes vs. the mouth in upright faces in ASD led to (1) improved discrimination accuracy; (2) increased activation in areas involved in social and emotional processing; (3) increased activation in subcortical face-processing areas. Our findings show that when explicitly cued to attend to the eyes, activation of cortical areas involved in face processing, including its social and emotional aspects, can be enhanced in autism. This suggests that impairments in face processing in autism may be caused by a deficit in social attention, and that giving specific cues to attend to the eye-region when performing behavioral therapies aimed at improving social skills may result in a better outcome.
Lower bounds for RAMs and quantifier elimination

For each natural number d we consider a finite structure M<sub>d</sub> whose universe is the set of all 0,1-sequence of length n=2<sup>d</sup>, each representing a natural number in the set {0,1,. ,2<sup>n</sup>-1} in binary form. The operations included in the structure are the four constants 0,1,2<sup>n</sup>-1,n, multiplication and addition modulo 2<sup>n</sup>, the unary function min{2<sup>x</sup>, 2<sup>n</sup>-1}, the binary functions ⌊ x/y⌋ (with ⌊ x/0 ⌋ =0), max(x,y), min(x,y), and the boolean vector operations, vee,- defined on 0,1 sequences of length n, by performing the operations on all components simultaneously. These are essentially the arithmetic operations that can be performed on a RAM, with wordlength n, by a single instruction. We show that there exists an ε>0 and a term (that is, an algebraic expression) F(x,y) built up from the mentioned operations, with the only free variables x,y, such that if G<sub>d</sub>(y), d=0,1,2,. , is a sequence of terms, and for all d=0,1,2,. , M<sub>d</sub> models ∀ x, [G<sub>d</sub>(x)-> ∃ y, F(x,y)=0], then for infinitely many integers d, the depth of the term G<sub>d</sub>, that is, the maximal number of nestings of the operations in it, is at least ε (log d)<sup>1/2</sup> = ε (log log n)<sup>1/2</sup>. The following is a consequence. We are considering RAMs N<sub>n</sub>, with wordlength n=2<sup>d</sup>, whose arithmetic instructions are the arithmetic operations listed above, and also have the usual other RAM instructions. The size of the memory is restricted only by the address space, that is, it is 2<sup>n</sup> words. The RAMs has a finite instruction set, each instruction is encoded by a fixed natural number independently of n. Therefore a program P can run on each machine N<sub>n</sub>, if n=2<sup>d</sup> is sufficiently large. We show that there exists an ε>0 and a program P, such that it satisfies the following two conditions. (i) For all sufficiently large n=2<sup>d</sup>, if P running on N<sub>n</sub> gets an input consisting of two words a and b, then, in constant time, it gives a 0,1 output P<sub>n</sub>(a,b). (ii) Suppose that Q is a program such that for each sufficiently large n=2<sup>d</sup>, if Q, running on N<sub>n</sub>, gets a word a of length n as an input, then it decides whether there exists a word b of length n such that P<sub>n</sub>(a,b)=0. Then, for infinitely many positive integers d, there exists a word a of length n=2<sup>d</sup>, such that the running time of Q on N<sub>n</sub> at input a is at least ε (log d)<sup>1/2</sup> (log log d)<sup>-1</sup> ≥ (log d)<sup>1/2-ε</sup>= (log log n)<sup>1/2-ε</sup>.
Sensorless friction-compensated passive lead-through programming for industrial robots

Industrial robots are important when the degree of automation in industry is increased. To enable the use of robots also when the products change rapidly, the programming must be quick and easy to perform. One way to accomplish this is to use lead-through programming, i.e., the user manually guides the robot. This paper presents a sensorless approach, and thus avoids the need for a typically expensive sensor. The method is based on disabling low-level joint controllers combined with gravity compensation. It is reported how the performance can be improved by compensating for friction. Further, a method for detecting small external torques is described, based on the use of the low-level joint controllers with increased integral gain. The lead-through programming is experimentally evaluated using two different industrial robots.
Fasting acylation-stimulating protein is predictive of postprandial triglyceride clearance Published, JLR Papers in Press, October 16, 2003. DOI 10.1194/jlr.M300214-JLR200

Postprandial plasma triglyceride (ppTG) and NEFA clearance were stratified by plasma acylation-stimulating protein (ASP) and gender to determine the contribution of fasting ASP in a normal population (70 men; 71 women). In the highest ASP tertile only, ASP decreased over 8 h (90 ± 9.7 nM to 70 ± 5.9 nM, P < 0.05 males; 61.9 ± 4.0 nM to 45.6 ± 6.2 nM, P < 0.01 females). Fasting ASP correlated positively with ppTG response. ppTG (P < 0.0001, 2-way ANOVA, both genders) and NEFA levels progressively increased from lowest to highest ASP tertile, with the greatest differences in males. By stepwise multiple regression, the best prediction of ppTG was: (fasting ASP + apolipoprotein B + insulin + TG; r = 0.806) for men and (fasting ASP + total cholesterol; r = 0.574) for women. Leptin, body mass index, and other fasting variables did not improve the prediction. Thus, in men and women, ASP significantly predicted ppTG and NEFA clearance and, based on lower ASP, women may be more ASP sensitive than men. Plasma ASP may be useful as a fasting variable that will provide additional information regarding ppTG and NEFA clearance.