Miracle-dz/UniFAR-FTUs huggingface dataset:
Influence of Temperature and Time of Acid Etching on the Surface Morphology of Titanium for Dental Implants

The surface morphology of dental implants affects the primary stability (mechanical stability), the secondary stability (osseointegration), and the tertiary stability (long-term stability). In this work, the effects of surface etching on commercially pure titanium grade 4 (cp Ti G4) were investigated. The objective was to study the influence of temperature and time of acid etching on surface roughness and morphology. The roughness parameters were measured with 3D optical surface profilers and the surface morphology was analyzed by scanning electron microscopy. The results showed that the roughness parameters Ra, Rsk, Rz, Rms, peak size and valley depth increased as the temperature and time of etching increased. An empirical mathematical model was developed relating the etching variables to the roughness parameters. Based on this mathematical model, one may choose the optimum temperature and time of etching to obtain the best surface roughness parameters for osseointegration.
Trustrace: Improving Automated Trace Retrieval through Resource Trust Analysis

Traceability is a task to create/recover traceability links among different software artifacts. It uses resources, such as an expert, source and target document, and traceability approach, to create/recover traceability links. However, it does not provide any guidance that how much we can trust on available resources. We propose Trustrace, a trust-based traceability recovery process, to improve expert trust on a recovered link and trust over the traceability inputs. Trustrace has three sub components, in particular, Link trust improver (LTI), traceability factor controller (TFC), and a hybrid traceability approach (HTA). LTI uses various source of information, such as temporal information, design documents, source code structure, and so on, to increase experts' trust over a link. To develop TFC, we will perform a systematic literature review and empirical studies to find out which factors impact the traceability-process inputs and document these factors in a trust pattern. TFC trust pattern will help practitioner and researchers to know which steps they can take to avoid/control these factors to improve their trust on these inputs. In the HTA, we will combine different traceability recovery approaches. All approaches have different positive and negative points, we will combine all the positive points of different approaches to increase experts' trust over the HTA. In Trustrace, HTA will implement the LTI model following TFC instructions to improve the expert trust over recovered link as well as precision and recall.
Final-focus Superconducting Magnets for SuperKEKB

SuperKEKB is now being operated with the final focus system as the phase-2 commissioning from March 16 th , 2018. The final focus system is the key device to attain the target luminosity of 8 × 10 35 cm -2 s -1 . Designing the system had started from 2009, and the construction was completed in March 2017. The final focus system consists of 55 superconducting magnets, and they were assembled carefully in two cryostats under the very tight space constraints. This paper describes the design configuration of the system, and reports the results of the commissioning on the beam lines in the SuperKEKB interaction region.
A novel BIST architecture with built-in self check

We propose an improved BIST architecture which supports on-chip comparison of signatures at no significant increase in area. The BILBO-based BIST architecture, used popularly in application-specific integrated circuits, suffers from two disadvantages. First, the initialization of the BILBO registers and the scanning out of the signatures are slow processes due to the sequential nature of these steps. Second, the test application time an a BILBO-based architecture does not depend on whether or not the circuit is faulty. It is typical to organize the testing procedure into one or more test sessions. In each test session, one or more functional modules are tested by applying pseudo-random test patterns. The responses of the functional modules are compressed into signatures which are captured into signature registers. Since the signature of the circuit is compared outside the chip, the test application must continue irrespective of whether or not a fault was detected in the middle of the testing process. More seriously, aliasing errors may result when a single signature is used and testing continues in spite of one or more faulty responses. The test architecture proposed in this paper is abbe to improve the above situation by performing on-chip signature check. Thus, we allow testing and signature comparison to occur concurrently. We show that such a test method can give rise to significant reduction in test application time.
Proteolytic activity of selected moulds in the first fermentation of black-seeded soysauce

Black-seeded soybean is preferred as normally it has higher protein content and would give black colour to the soyfiltrate for making soysauce. Mould is usually used in the first fermentation of soysauce making to prepare koji with high soluble protein as a media for the subsequent bacteria fermentation in brine solution. Black-seeded soybean of Detam 1 variety was used as the soysauce ingredient. The trial was a randomized complete design with four replicates. The treatments were (1) Rhizopus oligosporus starter (in flour form) with two day-fermentation, (2) similar R. oligosporus starter with three-day fermentation, (3) Aspergillus sojae (pure culture) with three-day fermentation and (4) A. sojae in flour form with three-day fermentation. The black-seeded soybean had 100-grain weight of 11.7 g, high protein content of 42.5% dw and fat content of 14.9% dw. Koji prepared using R. oligosporus starter with two-day fermentation had the lowest protein content (48.9% dw). Both starters of A. sojae culture and flour gave the highest soluble protein content of koji (41.0-41.5% dw), followed by R. oligosporus starter with 3 day-fermentation (35.2% dw). Whilst the lowest value was noted in koji prepared using R. oligosporus starter with two day-fermentation (30.8% dw). This suggests that both A. sojae starters had similar proteolitic activity and higher than that of R. oligosporus starter. In terms of practical application and maintenance of the mould viability by soysauce processors, the use of A. sojae flour starter with three-day fermentation is suggested.
Probability density of response times and Neurophysiology of Cognition

We discuss several markers of the probability densities of response times — specifically those with power-law tails — that allow us to gain insights into neurophysiology of cognition. We argue that combining individual subjects’ data into a single set for a distribution-function analysis allows for a better comparison of a group of interest to a control group. We illustrate our findings using time response trials with dyslexic children.
Estimation and optimisation of effective thermal conductivity for polymer matrix composites with hybrid inclusions

Composites with hybrid inclusions have shown remarkable thermal conductivity enhancement over composites with a single type of inclusion. However, to achieve maximum thermal conductivity enhancement, the optimum ratio of inclusions in the hybrid mix needs to be determined. In this communication, an effective medium theory based model for the estimation of effective thermal conductivity of composites with hybrid inclusions is presented. The proposed model accurately captures the synergic effect of hybrid inclusions within the composite and can be used to optimise the filler ratio in the hybrid mix. The model has been validated against several published experimental results and is found to be in good agreement with them. Parametric studies have also been carried out to study the effect of material and model parameters on the optimum ratio of hybrid inclusions.
Retinal degeneration in cone photoreceptor cell-ablated transgenic mice.

PURPOSE To examine the effect of loss of cone photoreceptor cells on retinal degeneration. METHODS We previously identified a cone photoreceptor cell-specific promoter of human cone transducin a-subunit (GNAT2) gene. In this report, a minigene, Trc-Tox176, that contains the GNAT2 promoter, an attenuated diphtheria toxin A-chain gene, and an enhancer element from human interphotoreceptor retinoid-binding protein (IRBP) was used to generate coneless transgenic mice. Transgenic mice were identified by PCR and the copy number of the transgene was determined by Southern hybridization, and examined by histology. RESULTS The results of immunostaining with anti-mouse GNAT2 antibodies and reverse transcription-PCR (RT-PCR) analysis with mRNA from the retinas of transgenic mice showed that cone photoreceptor cells were ablated in one of four transgenic mouse lines. The ablation of cone cells began at postnatal day 8, at the same time as the expression of endogenous GNAT2. An age-related rod degeneration was also found in this cone-ablated mouse line, beginning at postnatal day 9, proceeding from the central retina to the peripheral retina. CONCLUSIONS Cone photoreceptor cells may play an important role in the survival of rod photoreceptor cells during mouse retina development.
Speaker verification via articulatory feature-based conditional pronunciation modeling with vowel and consonant mixture models

Articulatory feature-based conditional pronunciation modeling (AFCPM) aims to capture the pronunciation characteristics of speakers by modeling the linkage between the states of articulation during speech production and the actual phones produced by a speaker. Previous AFCPM systems use one discrete density function for each phoneme to model the pronunciation characteristics of speakers. This paper proposes using a mixture of discrete density functions for AFCPM. In particular, the pronunciation characteristics of each phoneme is modeled by two density functions: one responsible for describing the articulatory features that are more relevant to vowels and the other for consonants. Verification scores are the weighted sum of the outputs of the two models. To enhance the resolution of the pronunciation models, four articulatory properties (front-back, liprounding, place of articulation, and manner of articulation) are used for pronunciation modeling. The proposed AFCPM is applied to a speaker verification task. Results show that using four articulatory features achieves a lower error rate as compared to using two features (manner and place of articulation) only. It was also found that dividing the articulatory properties into two groups is an effective means of solving the data-sparseness problem encountered in the training phase of AFCPM systems.
Reduced Connexin26 in the Mature Cochlea Increases Susceptibility to Noise-Induced Hearing Loss in Mice

Connexin26 (Cx26, encoded by GJB2) mutations are the most common cause of non-syndromic deafness. GJB2 is thought to be involved in noise-induced hearing loss (NIHL). However, the role of Cx26 in NIHL is still obscure. To explore the association between Cx26 and NIHL, we established a Cx26 knockdown (KD) mouse model by conditional knockdown of Cx26 at postnatal day 18 (P18), and then we observed the auditory threshold and morphologic changes in these mice with or without noise exposure. The Cx26 KD mice did not exhibit substantial hearing loss and hair cell degeneration, while the Cx26 KD mice with acoustic trauma experienced higher hearing loss than simple noise exposure siblings and nearly had no recovery. Additionally, extensive outer hair cell loss and more severe destruction of the basal organ of Corti were observed in Cx26 KD mice after noise exposure. These data indicate that reduced Cx26 expression in the mature mouse cochlea may increase susceptibility to noise-induced hearing loss and facilitate the cell degeneration in the organ of Corti.
Ambiguity Made Precise: A Comparative Foundation

There is no doubt that the subjective expected utility (SEU) theory of decision making under uncertainty of Savage (1954) is solidly established as the choice-theoretic underpinning of modern economic theory. However, Ellsberg (1961)'s famous thought experiment shows that SEU cannot take into account the possibility that the information a decision maker (DM) has about some uncertain event (that is relevant to her choice) be vague or imprecise, and that such "ambiguity" might affect her behavior.
Word association tests of associative memory and implicit processes: Theoretical and assessment issues

Word association is one of the most commonly used measures of association in cognitive science. These restS have been used ro infer association parameters in normative studies, to derive cues and primes used in diverse paradigms (semantic priming, cued recall, illusory memory), to test implicit memory in experimental studies, and to suggest the operation of implicit processes in nonexperimental work. This chapter briefly ourlines some of the historical routes and current controversies about association and summarizes basic cognitive research applying associative tests. The authors then describe benefits and limitations of the rests, as well as implications for theory and interventions on drug use. This chapter briefly outlines some of the historical routes of word association and then summarizes several of the major streams of basic cognitive research revealing the value of these tests. We delineate several current controversies from this basic research and suggest why they are critical for understanding drug-related cognitions and behavior. We then address benefits, limitations, and further implications of the testS. A BRIEF HISTORY OF WORD ASSOCIATION The concept of association can be traced back tO Aristotle and was not refined substantially until the effort of the British empiricists (Dawson, 2004). Some of Aristotle's primary concepts such as contiguity, similarity, and sequence effects anticipated a variety of associationist and connectionist models of the last AUTHOR'S NOTE: This chapter was supported by a grant from the National Institute on Drug Abuse, DA16094.
Modifiable risk behaviors in patients with head and neck cancer

Use of tobacco products, excessive alcohol consumption, and high‐risk sexual behaviors increase the risk of developing head and neck cancer and impacts treatment effectiveness after diagnosis. This study examined smoking and engagement in other modifiable behavioral risk factors and human papillomavirus (HPV) status in patients with head and neck cancer in order to facilitate identification and foster development of targeted interventions in high‐risk patients.
Component-based registration with curvature descriptors for expression insensitive 3d face recognition

Deformations caused by facial expression variations complicate the task of 3D face registration which is vital for successful 3D face recognition systems. In this work, we propose to use a hierarchical component-based face registration technique capable of handling the difficulties caused by non-rigid nature of faces. Local components independently registered by the iterative closest point (ICP) algorithm provides a fast registration with the use of a generic face model and does not suffer from non-rigidity of human facial surface. Invariance of the proposed approach is further increased by utilizing curvature-based 3D surface descriptors. Identification experiments conducted on the multi-expression Bosphorus database reveal that the accuracy of the classical ICP-based approach can be significantly increased under extreme expression variations.
Tolerance of Human and Rat Atrial Muscle to Hypothermia and Anoxia

Evidence is presented which strongly suggests the preservation of contractility of human atrial muscle when hypothermia of 25 to 31 C. is used during anoxia. Parallel studies were carried out on albino rat atria which gave results similar to that of the human tissue. This report adds further evidence that hypothermia is valuable in open-heart surgery when anoxic is indicated for the repair of cardiac malformations.
The Establishment of a Hyperactive Structure Allows the Tumour Suppressor Protein p53 to Function through P-TEFb during Limited CDK9 Kinase Inhibition

CDK9 is the catalytic subunit of positive elongation factor b (P-TEFb) that controls the transition of RNA polymerase II (RNAPII) into elongation. CDK9 inhibitors block mRNA synthesis and trigger activation of the stress-sensitive p53 protein. This in turn induces transcription of CDKN1A (p21) and other cell cycle control genes. It is presently unclear if and how p53 circumvents a general P-TEFb-requirement when it activates its target genes. Our investigations using a panel of specific inhibitors reason for a critical role of CDK9 also in the case of direct inhibition of the kinase. At the prototypic p21 gene, the activator p53 initially accumulates at the pre-bound upstream enhancer followed—with significant delay—by de novo binding to a secondary enhancer site within the first intron of p21. This is accompanied by recruitment of the RNAPII initiation machinery to both elements. ChIP and functional analyses reason for a prominent role of CDK9 itself and elongation factor complexes PAF1c and SEC involved in pause and elongation control. It appears that the strong activation potential of p53 facilitates gene activation in the situation of global repression of RNAPII transcription. The data further underline the fundamental importance of CDK9 for class II gene transcription.
A DTI study to probe tumor microstructure and its connection with hypoxia

Solid tumors have chaotic organization of blood vessels, disruptive nerve paths and muscle fibers that result in a hostile and heterogeneous microenvironment. These tumor regions are often hypoxic and resistant to radiation therapy. The knowledge of partial pressure of oxygen concentration (pO2), in conjunction with the information about tissue organization, can predict tissue health and may eventually be used in combination with intensity-modulated radiation therapy (IMRT) for targeted destruction of radiation-resistant areas, while sparing healthy tissues. Diffusion tensor imaging (DTI) based parameter fractional anisotropy (FA) can be used to assess organization of tissue microstructure, whereas the pO2 can be measured using electron paramagnetic resonance oxygen imaging (EPROI). This study is our first step to connect these two important physiological parameters. We calculated FA in fixed fibrosarcoma (FSa) grown in hind leg of nude mice (n = 6) using preclinical 9.4 T MRI. The FA in tumor region (0.34 ± 0.014) was found to be lower when compared to normal surrounding region (0.36 ± 0.013). We hypothesized that the change in FA is directly correlated with the change in oxygen concentration in tumor. We present preliminary in vivo results showing a positive correlation (R = 0.85, p = 0.017) between the FA and pO2 values acquired for MCa4 tumor (n = 1) using DTI and EPROI.
A Client-Server Extension to PICSearch system 2 Related Work

The large numberof application domains, increasedcomputationalpower and the possibility to have massive databases have directed many researchers to the area of image retrieval. The remarkable research effort on this particular area has produced a lot of image retrieval algorithms. However, there have not been freely distributed and portable platforms where to easily embed these algorithms. We have made effort to facilitate the work of these researchers by offering a framework system for image retrieval. Earlier, we have introduced a portable, extendible and freely available framework system which can be used with local databases. In this paper we introduce a client-server extension to that PICSearch system. We give an overview to the architectural solution of the client-server system and we present some key ideas of our data communication protocol to minimize the communication rate.
Speckle-based portable device for in-situ metrology of x-ray mirrors at Diamond Light Source

For modern synchrotron light sources, the push toward diffraction-limited and coherence-preserved beams demands accurate metrology on X-ray optics. Moreover, it is important to perform in-situ characterization and optimization of X-ray mirrors since their ultimate performance is critically dependent on the working conditions. Therefore, it is highly desirable to develop a portable metrology device, which can be easily implemented on a range of beamlines for in-situ metrology. An X-ray speckle-based portable device for in-situ metrology of synchrotron X-ray mirrors has been developed at Diamond Light Source. Ultra-high angular sensitivity is achieved by scanning the speckle generator in the X-ray beam. In addition to the compact setup and ease of implementation, a user-friendly graphical user interface has been developed to ensure that characterization and alignment of X-ray mirrors is simple and fast. The functionality and feasibility of this device is presented with representative examples.
Managing Variability in Software Product Lines

Software Product Lines are large systems intended for reuse in concrete products. As such these large systems provide reusable architecture and implementation that the individual products have in common. The differences between the product are left open. We refer to these open spots as variability points. In this article we provide a conceptual framework of terminology for the concept of variability and we discuss how variability can be managed in Software Product Lines.
Transient heat transfer characterization of impinging hot / cold jets by analytical IHCP

Unknown transient surface temperature and heat flux distribution at the impingement side (front side) is estimated from known temperature distribution at non-impingement side (back side) using analytical solution to three dimensional inverse heat conduction problem (IHCP). Back side input temperature data are obtained by running forward code in Fluent. Hot as well as cold impinging jets are characterized with the help of this solution. Laminar and turbulent jets at nozzle to plate spacing (Z/d) equal to 4 are considered. Hot gas at temperature 500 K and 3000 K is impinged on a 1 mm flat plate which considered initially at temperature 300 K in case of heating application. Whereas in cooling application, flat plate is initially assumed at temperature 673 K and isothermal air jet at 293 K is impinged on it. The temperature and heat flux estimation data by present technique is in very good agreement with the simulation data.