Miracle-dz/UniFAR-FTUs huggingface dataset:
Low level exposure to cadmium and early kidney damage: the OSCAR study

OBJECTIVES To study the dose-response relation between cadmium dose and renal tubular damage in a population of workers and people environmentally or occupationally exposed to low concentrations of cadmium. METHODS Early kidney damage in 1021 people, occupationally or environmentally exposed to cadmium, was assessed from cadmium in urine to estimate dose, and protein HC (α1-microglobulin) in urine to assess tubular proteinuria. RESULTS There was an age and sex adjusted correlation between cadmium in urine and urinary protein HC. The prevalence of tubular proteinuria ranged from 5% among unexposed people to 50% in the most exposed group. The corresponding prevalence odds ratio was 6.0 (95% confidence interval (95% CI) 1.6 to 22) for the highest exposure group, adjusted for age and sex. Multiple logistic regression analysis showed an increasing prevalence of tubular proteinuria with urinary cadmium as well as with age. After adjustment to the mean age of the study population (53 years), the results show an increased prevalence of 10% tubular proteinuria (taking into account a background prevalence of 5%) at a urinary cadmium concentration of 1.0 nmol/mmol creatinine. CONCLUSION Renal tubular damage due to exposure to cadmium develops at lower levels of cadmium body burden than previously anticipated.
Climas urbanos y contaminación atmosférica en Santiago de Chile

Current relationships between urban temperatures and particulate matter concentrations at a scale that is representative of the whole city have been analyzed, highlighting a clear division in two zones, the eastern and western part of the city during the days that register the worst air pollution. On a more detailed scale, based on characteristic urban morphology types, land uses and extensions are correlated with vegetation cover and surface temperatures in so-called climatic sub-zones, in the municipalities of Penalolen, Santiago Centro and Cerrillos, that represent different urban locations, natural cover and socioeconomic variables across the city. The article concludes that there are areas with adverse conditions for the population and configurations that highlight the heterogeneity and diversity of these municipalities.
THE INFLUENCE OF CULTURAL ADAPTATION ON DEPRESSIVE SYMPTOMS AMONG YOUNG HISPANIC IMMIGRANTS

ii LIST OF ABBREVIATIONS & SYMBOLS . iii ACKNOWLEDGEMENTS . iv LIST OF TABLES . viii LIST OF FIGURES . ix CHAPTER 1 RESEARCH PROBLEM . 1 Background . 1 Purpose of the Study . 7 Study Aims . 8 Significance of Study to Research Area . 8 Significance of Study to Social Work . 9 CHAPTER 2 LITERATURE REVIEW . 10 Youthful Migration Among Hispanic Immigrants, Cultural Adaptation, & Mental Illness . 10 Ethnicity & Culture . 14 Acculturation . 17 Acculturation Gap Distress Model . 21 Social Identity Theory & The Immigrant Paradigm . 23 Family Cohesion, Subjective Social Status, & Discrimination Among Hispanic Immigrants . 28 Psychosocial Context . 31 Depressive Symptoms . 34 Gaps in the Literature . 36 Research Questions . 37 Conclusion . 37
Gambling: a dependence without a drug

This paper reviews the research literature on excessive and persistent gambling with particular emphasis on the reasons why such behaviour has come to be classified among the addictions. The characteristics of gamblers who seek help from mental health agencies are discussed in relation to the diagnostic criteria for ‘pathological gambling’ given in DSM III-R.5 Although there have been few controlled treatment evaluations the range of therapeutic approaches employed in Australia, the U.S.A. and the U.K. are reviewed. A variety of theoretical models have been proposed to explain the psychological and physiological processes that may underlie the progression of this behavior from an infrequent leisure habit to a costly, all-engrossing, addictive-like preoccupation. These models are critically reviewed in the light of existing empirical findings. The evidence that excessive gambling shows features of dependence despite the absence of a psychoactive agent is evaluated. The concluding section of the paper explo.
Architecture-level Simulations with Rapid Power Estimations for Security Processors with Multiple Power Domains ∗

The power dissipation is the concern for SoC designs and embedded systems to extend battery life. Techniques like dynamic voltage scaling (DVS), power gating (PG), and multiple domain partitioning help provide mechanisms to reduce dynamic and static powers. Based on those techniques, the control system can be system software or hardware monitors. In ether cases, energy estimations in the architecture level are needed to facilitate the design space explorations of architecture and software scheduling designs for energy reductions. In this paper, we propose an architecture-level simulation environment for security processors with power estimation. The simulation environment includes a transaction-level modeling (TLM) simulator implemented in SystemC with multiple power domains, an analytical model, a workload generator, power parameter banks, versatile outputs, and succinct GUIs. Architecture developers can use it to evaluate different architecture configurations and retrieve performance results and power estimations. System software developers can use these tools for experiments in devising power-aware scheduling methods on security processors for power dissipation reduction.
For ethical, economic and scientific reasons, health-relevant degree theses must be made publicly accessible

In an article published in the James Lind Library , Gordon Guyatt and Andy Oxman – pioneers in the development of methods to support evidence-based medicine – explain why those of us working in the field of healthcare owe a methodological debt to the social sciences.1 American social scientists – including one who introduced the term ‘meta-analysis’2 – pioneered assessments of the effects of educational and social interventions using systematic reviews. They made clear that reviews should be conceptualised as research projects, and so needed to use scientifically defensible methods.3 One of the most important methodological contributions made by the social scientists in the 1970s was to point out that, as systematic reviews were based on surveys of the relevant primary evidence, these surveys needed to identify the relevant studies as completely as possible. The consequence of failing to take account of evidence that had not been published in academic journal articles was made clear by Mary Lee Smith and her colleagues in articles published more than three decades ago.4 5 For example, they tabulated the results of 12 meta-analyses that had used data derived both from published journal articles and from studies that had not been formally published. In every one of the 10 meta-analyses in which the comparison could be made, the …
Mitochondrial Genome Recombination in the Zone of Contact Between Two Hybridizing Conifers

Variation in mitochondrial DNA was surveyed at four gene loci in and around the zone of contact between two naturally hybridizing conifers, black spruce (Picea mariana) and red spruce (P. rubens) in northeastern North America. Most of the mtDNA diversity of these species was found in populations next to or into the zone of contact, where some individuals bore rare mitotypes intermediate between the common mitotypes observed in the allopatric areas of each species. Sequence analysis and tests for mtDNA recombination point to this phenomenon, rather than to recurrent mutation, as the most tenable hypothesis for the origin of these rare mitotypes. From the 10 mitotypes observed, at least 4 would be the product of recombination between 4 of the 5 putative ancestral mitotypes. Tests for cytonuclear disequilibrium and geographical structure of the putative recombinant mitotypes suggest that mtDNA recombination is not frequent and relatively recent on the geological time scale. mtDNA recombination would have been promoted by transient heteroplasmy due to leakage of paternal mtDNA since the Holocene secondary contact between the two species.
The Role of the Syllable in Lexical Segmentation in French: Word-Spotting Data

Three word-spotting experiments assessed the role of syllable onsets and offsets in lexical segmentation. Participants detected CVC words embedded initially or finally in bisyllabic nonwords with aligned (CVC.CVC) or misaligned (CV.CCVC) syllabic structure. A misalignment between word and syllable onsets (Experiment 1) produced a greater perceptual cost than a misalignment between word and syllable offsets (Experiments 2 and 3). These results suggest that listeners rely on syllable onsets to locate the beginning of words. The implications for theories of lexical access in continuous speech are discussed.
Plagiocephaly and Brachycephaly in the First Two Years of Life: A Prospective Cohort Study

Objectives.Although referrals for nonsynostotic plagiocephaly (NSP) have increased in recent years, the prevalence, natural history, and determinants of the condition have been unclear. The objective of this study was to assess the prevalence and natural history of NSP in normal infants in the first 2 years of life and to identify factors that may contribute to the development of NSP. Methods.Two hundred infants were recruited at birth. At 6 weeks, 4 months, 8 months, 12 months, and 2 years, the head circumference shape was digitally photographed, and head shape was quantified using custom-written software. At each age, infants were classified as cases when the cephalic index was ≥93% and/or the oblique cranial length ratio was ≥106%. Neck rotation and a range of infant, infant care, socioeconomic, and obstetric factors were assessed. Results.Ninety-six percent of infants were followed to 12 months, and 90.5% were followed to 2 years. Prevalence of plagiocephaly and/or brachycephaly at 6 weeks and 4, 8, 12, and 24 months was 16.0%, 19.7%, 9.2%, 6.8%, and 3.3% respectively. The mean cephalic index by 2 years was 81.6% (range: 72.0%–102.6%); the mean oblique cranial length ratio was 102.6% (range: 100.1%–109.4%). Significant univariate risk factors of NSP at 6 weeks include limited passive neck rotation at birth, preferential head orientation, supine sleep position, and head position not varied when put to sleep. At 4 months, risk factors were male gender, firstborn, limited passive neck rotation at birth, limited active head rotation at 4 months, supine sleeping at birth and 6 weeks, lower activity level, and trying unsuccessfully to vary the head position when putting the infant down to sleep. Conclusions.There is a wide range of head shapes in infants, and prevalence of NSP increases to 4 months but diminishes as infants grow older. The majority of cases will have resolved by 2 years of age. Limited head rotation, lower activity levels, and supine sleep position seem to be important determinants.
QoE-Based Server Selection for Content Distribution Networks

As current server capacity and network bandwidth become increasingly overloaded by the rapid growth of high quality emerging multimedia services such as mobile online gaming, social networking or IPTV, a critical factor of success of these multimedia services becomes the end-user perception of quality while them using the service. As a result, user-centered approaches that consider quality of experience (QoE) constitute the current design trend for network systems of content providers and network operators. A content distribution network (CDN) that replicates the content from original servers to the replicated servers close to end users is actually an effective solution to improve network quality. We propose a QoE-based server selection algorithm in the context of a CDN architecture. Using realistic characteristics of the server selection process, we formalize our selection model as a sequential decision problem solved by the multi-armed bandit (MAB) paradigm. By using realistic experiments, we demonstrate that our approach yields significant improvements in term of user perception compared to traditional methods (such as Fastest, Closest and Round Robin).
Age-related lobular involution and risk of breast cancer.

BACKGROUND As women age, the lobules in their breasts undergo involution or regression. We investigated whether lobular involution in women with benign breast disease was associated with subsequent breast cancer risk. METHODS We examined biopsy specimens of 8736 women in the Mayo Benign Breast Disease Cohort from whom biopsy samples were taken between January 1, 1967, and December 31, 1991. Median follow-up for breast cancer outcomes was 17 years. We classified lobular involution in the background breast tissue as none (0% involuted lobules), partial (1%-74%), or complete (> or = 75%). Subsequent breast cancer events and data on other risk factors were obtained from medical records and follow-up questionnaires. To estimate relative risks (RRs), standardized incidence ratios were calculated by use of incidence rates from the Iowa Surveillance, Epidemiology, and End Results (SEER) Registry. All statistical tests were two-sided. RESULTS Distribution of extent of involution was none among 1627 (18.6%) women, partial among 5197 (59.5%), and complete among 1912 (21.9%). Increased involution was positively associated with increased age and inversely associated with parity (both P<.001). The relative risk for the entire cohort of 8736 women, compared with the Iowa SEER population, was 1.40 (95% CI = 1.30 to 1.51). Risk of breast cancer was associated with the extent of involution (for no involution, RR [i.e., observed versus expected] = 1.88, 95% confidence interval [CI] = 1.59 to 2.21; for partial involution, RR = 1.47, 95% CI = 1.33 to 1.61; and for complete involution, RR = 0.91, 95% CI = 0.75 to 1.10; test for heterogeneity P<.001). Lobular involution modified risk in all subsets (e.g., among women with atypia, for no involution, RR = 7.79, 95% CI = 3.56 to 14.81; for partial involution, RR = 4.06, 95% CI = 3.03 to 5.33; and for complete involution, RR = 1.49, 95% CI = 0.41 to 3.82; P = .003). CONCLUSIONS In this large cohort of women with benign breast disease, lobular involution was associated with reduced risk of breast cancer. Aberrant involution may be a biologically important phenomenon in breast cancer biology.
Who's on and why are they there?: A study of visitors to electoral candidates' websites in Taiwan

This study is aimed mainly at portraying the profiles of the visitors to presidential candidate's websites in Taiwan's 2000 election. An online survey was conducted, initiated by visitors' clicking button ads on different candidates' websites, which linked them to a questionnaire. The results reveal that mainly the site visitors were male, young, and highly educated. Most visitors agreed that their motive to visit candidates' websites were to acquire candidate‐related information, and to better understand the candidates' standing on policies. Those who visited a particular candidate's site tended to be supporters of that candidate.
When More Media Equals Less News: Patterns of Content Homogenization in Argentina's Leading Print and Online Newspapers

This article examines content homogeneity, understood as the degree to which different media focus on the same stories during a particular news cycle, in Argentina's leading print and online newspapers. It focuses on the role of technical practices across media and over time—during a decade for print and during 24 hours for online. The analysis shows three main patterns of homogenization: (a) an increase in the level of homogeneity in print newspapers tied to their online counterparts' practice of publishing breaking and developing stories during the day, (b) an increase in the level of homogeneity in online newspapers as the day unfolds, and (c) a densely interconnected web of homogeneity across print and online newspapers in 2005. We draw from these findings to make contributions to research on online news and media sociology and to reflect upon the direction and meaning of changes in journalistic form in the current media environment.
Time Limits: The Effects on Welfare Use and Other Consumption-Smoothing Mechanisms

We use data from the Survey of Income and Program Participation covering the period 1989-2006 to investigate the impact that time limits on receipt of Temporary Assistance for Needy Families have on female-headed family outcomes, including welfare use, employment and living arrangements. The effects of time limits depend on the stock of remaining months of eligibility, which in turn depends on the state time limit and on family’s welfare use since the policy was implemented. Since the latter is potentially endogenous to current outcomes, we form a prediction of remaining eligibility based on state rules and observable family characteristics. For families who are predicted to have hit the limit, we find evidence of enforcement of the policy, which causes monthly income from welfare to drop by an average of $250. This loss is not offset by increases in other income sources: not only there is no significant change in earnings (despite a sizable increase in the likelihood that the mother works), but also income from other transfer programs (such as SSI and Food Stamps) decreases – resulting in increasing rates of deep poverty among these families. Additional analyses suggest that doubling up is a way for families who timed out of welfare to share housekeeping expenses.
Probing microscopic origins of confined subdiffusion by first-passage observables

Subdiffusive motion of tracer particles in complex crowded environments, such as biological cells, has been shown to be widespread. This deviation from Brownian motion is usually characterized by a sublinear time dependence of the mean square displacement (MSD). However, subdiffusive behavior can stem from different microscopic scenarios that cannot be identified solely by the MSD data. In this article we present a theoretical framework that permits the analytical calculation of first-passage observables (mean first-passage times, splitting probabilities, and occupation times distributions) in disordered media in any dimensions. This analysis is applied to two representative microscopic models of subdiffusion: continuous-time random walks with heavy tailed waiting times and diffusion on fractals. Our results show that first-passage observables provide tools to unambiguously discriminate between the two possible microscopic scenarios of subdiffusion. Moreover, we suggest experiments based on first-passage observables that could help in determining the origin of subdiffusion in complex media, such as living cells, and discuss the implications of anomalous transport to reaction kinetics in cells.
Robust Flexible Capacitive Surface Sensor for Structural Health Monitoring Applications

Early detection of possible defects in civil infrastructure is vital to ensuring timely maintenance and extending structure life expectancy. The authors recently proposed a novel method for structural health monitoring based on soft capacitors. The sensor consisted of an off-the-shelf flexible capacitor that could be easily deployed over large surfaces, the main advantages being cost-effectiveness, easy installation, and allowing simple signal processing. In this paper, a capacitive sensor with tailored mechanical and electrical properties is presented, resulting in greatly improved robustness while retaining measurement sensitivity. The sensor is fabricated from a thermoplastic elastomer mixed with titanium dioxide and sandwiched between conductive composite electrodes. Experimental verifications conducted on wood and concrete specimens demonstrate the improved robustness, as well as the ability of the sensing method to diagnose and locate strain.
The United States and Idi Amin: Congress to the Rescue

Idi Amin's brutal regime in Uganda presented a series of unique and complicated dilemmas for American policymakers. Despite its stated commitment to the cause of human rights, the administration of President Jimmy Carter opposed the imposition of economic sanctions against Uganda. Congress, however, determined that the levels of atrocity and repression which marked Amin's dictatorship warranted a new foreign policy approach. In addition, by providing another example of changing executive-legislative relations in foreign policy, the October 10, 1978, embargo of United States' trade with Uganda established new precedents in America's commitment to human rights. Amin came to power in Uganda as a result of a 1971 coup against President Milton Obote. During his eight-year regime, over 100,000 people were murdered and thousands of others were expelled (U.S. Congress, House, Subcommittee on Africa [hereafter U.S. Congress, House], 1978: 5; International Commission of Jurists, 1977). A number of Amin's victims received worldwide press attention. Two Americans, Nicholas Stroh, a thirty-three year old journalist, and Robert Siedele, a forty-six year old lecturer, were brutally killed in 1971. The expulsion of the Asians from Uganda in 1972 attracted international attention. An El Al jetliner hijacked in July 4, 1976, again thrust Uganda into the headlines. In the aftermath of the daring Israeli raid to rescue the hostages at Entebbe airport in Kampala, the Ugandan authorities murdered Mrs. Dora Bloch, a seventy year old passenger who had been removed to a hospital. The 1977 murder of Ugandan Anglican Archbishop Janai Luwuum, together with two government officials, was condemned throughout the world. This event prompted Senator Clifford Case (R-NJ) to introduce Senate Resolution 175, expressing the sense of the Senate that the regime in Uganda should be condemned.
Multicenter mapping of structural network alterations in autism

Autism spectrum disorders (ASD) are a group of neurodevelopmental conditions primarily characterized by abnormalities in social cognition. Abundant previous functional MRI studies have shown atypical activity in networks encompassing medial prefrontal cortex (mPFC) and medial parietal regions corresponding to posterior cingulate cortex and precuneus (PCC/PCU). Conversely, studies assessing structural brain anomalies in ASD have been rather inconsistent. The current work evaluated whether structural changes in ASD can be reliability detected in a large multicenter dataset. Our comprehensive structural MRI framework encompassed cortical thickness mapping and structural covariance analysis based on three independent samples comprising individuals with ASD and controls (n = 220), selected from the Autism Brain Imaging Data Exchange open‐access database. Surface‐based analysis revealed increased cortical thickness in ASD relative to controls in mPFC and lateral prefrontal cortex. Clusters encompassing mPFC were embedded in altered inter‐regional covariance networks, showing decreased covariance in ASD relative to controls primarily to PCC/PCU and inferior parietal regions. Cortical thickness increases and covariance reductions in ASD were consistent, yet of variable effect size, across the different sites evaluated and measurable both in children and adults. Our multisite study shows regional and network‐level structural alterations in mPFC in ASD that, possibly, relate to atypical socio‐cognitive functions in this condition. Hum Brain Mapp 36:2364–2373, 2015. © 2015 Wiley Periodicals, Inc.