Miracle-dz/UniFAR-FTUs huggingface dataset:
Neuro-Fuzzy Systems Modeling Tools for Bacterial Growth

Many techniques have been used in classification of bacterial growth-non-growth database are network based. This paper proposes adaptive neuro-fuzzy system for classifying the bacterial growth/non-growth and modeling the growth history. A brief description of the neuro-fuzzy intelligent systems scheme is proposed. The performance of neuro-fuzzy system is investigated for their quality and accuracy in classification of growth/no-growth state of a pathogenic Escherichia coli R31 in response to temperature and water activity. A comparison with the most common used statistics and data mining classifiers was carried out. The neuro-fuzzy system classifier was found to do better than both linear/nonlinear regression and multilayer neural networks. Results show bright future in implementing it in food science and medical industry.
Recognition and Predicting Lava Underground Based on Regression Support Vector Machine Using Seismic Signal

Deep lava maybe contain petroleum and natural gas or CO2 gas. It is very important to find lava but the lava is in deep stratum and has complex structure and less sample data, so it is difficult to find lava stratum. There were some methods to predict where the lava is but some problem also was in them such as the precision of recognition and predicting was not high limited by the small number of sample, a regression SVM method of recognition and predicting underground lava is proposed, moreover, we propose a self-adaptive parameter adjust iterative algorithm to confirm SVM parameters, thereby enhancing the converging speed and the predicting accuracy. The prediction results of an example prove this method validity and practicability
Interaction of barbiturate analogs with the Torpedo californica nicotinic acetylcholine receptor ion channel.

Barbiturate-induced anesthesia is a complex mechanism that probably involves several ligand-gated ion channel superfamilies. One of these superfamilies includes the archetypical nicotinic acetylcholine receptor (nAChR), in which barbiturates act as noncompetitive antagonists. In this regard, we used the Torpedo californica nAChR and a series of barbiturate analogs to characterize the barbiturate binding site(s) on this superfamily member. [(14)C]Amobarbital binds to one high-affinity (K(d) = 3.7 microM) and several (approximately 11) low-affinity (K(d) = 930 microM) sites on the resting and desensitized nAChRs, respectively. Characteristics of the barbiturate binding site on the resting nAChR include: (1) a tight structure-activity relationship. For example, the barbiturate isobarbital [5-ethyl-5'-(2-methylbutyl) barbituric acid] is >10-fold less potent than its formula isomer amobarbital [5-ethyl-5'-(3-methylbutyl) barbituric acid] in inhibiting [(14)C]amobarbital binding. (2) A binding locus within the pore of the nAChR ion channel. Each of the barbiturate analogs inhibited the binding of [(3)H]tetracaine or photoincorporation of 3-trifluoromethyl-3-(m-[(125)I]iodophenyl) diazirine in a mutually exclusive manner. (3) Stereoselective binding. The R(+)-enantiomers of isobarbital and pentobarbital are approximately 2-fold more potent in inhibiting 3-trifluoromethyl-3-(m-[(125)I]iodophenyl) diazirine photoincorporation than the S(-)-enantiomers. Finally, molecular modeling suggests that within the channel, the pyrimidine ring of the barbiturate is located just above the highly conserved leucine ring (M2--9; e.g., delta Leu-265), whereas the 5' side chain projects downward, and depending upon its conformation, introduces steric hindrance to binding because of the restriction in the lumen of the channel introduced by the leucine side chains.
Ovarian Cancer Stem Cells: A New Target for Cancer Therapy

Ovarian cancer is a highly lethal disease among all gynecologic malignancies and is the fifth leading cause of cancer-related death in women. Although the standard combination of surgery and chemotherapy was initially effective in patients with ovarian cancer, disease relapse commonly occurred due to the generation of chemoresistance. It has been reported that cancer stem cells (CSCs) are involved in drug resistance and cancer recurrence. Over the past decades, increasing studies have been done to identify CSCs from human ovarian cancer cells. The present paper will summarize different investigations on ovarian CSCs, including isolation, mechanisms of chemoresistance, and therapeutic approaches. Although there are still numerous challenges to translate basic research to clinical applications, understanding the molecular details of CSCs is essential for developing effective strategies to prevent ovarian cancer and its recurrence.
Integrated CMOS-MEMS technology and its applications

The paper describes integrated CMOS-MEMS technology and its applications. We discuss the features of integrated complementary metal-oxide-semi-conductor-microelectromechanical systems (CMOS- MEMS). The prospect of this integration is also presented. A MEMS fingerprint sensor and a low-voltage radio frequency (RF) CMOS-MEMS switch are the case studies discussed. In conclusion, it is confirmed that the integrated CMOS-MEMS technology will pave the way for the more than Moore technology.
Arc spaces, motivic integration and stringy invariants

The concept of motivic integration was invented by Kontsevich to show that birationally equivalent Calabi-Yau manifolds have the same Hodge numbers. He constructed a certain measure on the arc space of an algebraic variety, the motivic measure, with the subtle and crucial property that it takes values not in R, but in the Grothendieck ring of algebraic varieties. A whole theory on this subject was then developed by Denef and Loeser in various papers, with several applications. Batyrev introduced with motivic integration techniques new singularity invariants, the stringy invariants, for algebraic varieties with mild singularities, more precisely log terminal singularities. He used them for instance to formulate a topological Mirror Symmetry test for pairs of singular Calabi-Yau varieties. We generalized these invariants to almost arbitrary singular varieties, assuming Mori’s Minimal Model Program. The aim of these notes is to provide a gentle introduction to these concepts. There exist already good surveys by Denef-Loeser [DL8] and Looijenga [Loo], and a nice elementary introduction by Craw [Cr]. Here we merely want to explain the basic concepts and first results, including the p-adic number theoretic pre-history of the theory, and to provide concrete examples. The text is a slightly adapted version of the ‘extended abstract’ of the author’s talks at the 12th MSJ-IRI ”Singularity Theory and Its Applications” (2003) in Sapporo. At the end we included a list of various recent results.
Folk Intuitions on Free Will

This paper relies on experimental methods to explore the psychological underpinnings of folk intuitions about free will and responsibility. In different conditions, people give conflicting responses about agency and responsibility. In some contexts, people treat agency as indeterminist; in other contexts, they treat agency as determinist. Furthermore, in some contexts people treat responsibility as incompatible with determinism, and in other contexts people treat responsibility as compatible with determinism. The paper considers possible accounts of the psychological mechanisms that underlie these conflicting responses.
BEHAVIOR EVALUATION AND LEARNING FROM AN INTERNALPOINT OF VIEWFran cois

This paper describes a new approach that makes a robot learn by evaluating its own performance based on the use of its resources. For a behavior-based robot, this means that learning is accomplished from the observation of behavior use over time. The acquired knowledge can then be exploited for future selection of behaviors. When applied to the multi-robot domain, this approach will make the robot nd regularities in its interactions with its environment and exploit them eeciently, eventually resulting in specialization within the group.
Acidification Process in the Area of the Abandoned Ľubietová - Podlipa Cu-Deposit, Slovakia / Proces Acidifikácie V Oblasti Opusteného Cu-Ložiska Ľubietová - Podlipa, Slovensko

Abstract Acidity in surroundings of the abandoned Ľubietová-Podlipa Cu-deposit depends predominantly on the geochemical behaviour (weathering) of particular minerals (mainly pyrite). The article presents the results of measurements of basic physicochemical parameters - pH and Eh in technogenic sediments and in surface and drainage water of a dump-field. Although the dump material shows a significant amount of mobility-able metals and thus also a potential to form acidity, a massive AMD formation in future is not probable. Abstrakt Acidita v okolí opusteného Cu-ložiska Ľubietová - Podlipa závisí predovšetkým od geochemického správania sa (zvetrávania) niektorých minerálov (hlavne pyritu). V článku sú prezentované výsledky meraní základných fyzikálno-chemických parametrov - pH a Eh v technogénnych sedimentoch a v povrchovej a drenážnej vode haldového poľa. Haldový materiál síce stále vykazuje značné množstvo mobilizovateľných kovov a teda aj istý potenciál tvoriť kyslosť, podľa výsledkov výpočtu rizika, k masívnejšej tvorbe AMD nebude v budúcnosti pravdepodobne dochádzať.
A personal mashup framework for mobile users

This paper proposes a framework to help improve the operability of mobile devices. End users can utilize websites in combination with less operation steps and create their own combinations on demand without any kind of programming. This paper also proposes a text extraction method which is required for the framework. It learns an extraction rule from one example.
QUEUEING NOTATION

Queueing theory is concerned with the mathematical analysis of systems that provide service to random demands. This theory has many application areas (e.g., industrial engineering, electrical engineering, computer science, telecommunications, and operations management). Consequently, the terminology and notation, while often intuitively sensible, are not always consistent. The mathematical theory is focused on simple (but meaningful) mathematical models that can be described in the precise terminology required for mathematical analysis. In this article, we give an overview of the notation and terminology used in describing the standard basic queueing models. In the basic queueing model, ‘‘customers’’ arrive (to request service), wait (if necessary) for a ‘‘server’’ to become available to provide the required service, and then leave. Thus the model consists of three components: (i) the (stochastic) arrival process, (ii) the (stochastic) service requirement, and (iii) the physical configuration of the servers and their operating rules. The objective of the theory is to understand the relationship between these components and the behavior (performance measures) of the system. In a now-classic 1953 paper, D.G. Kendall [1] proposed the following notation to describe a queueing model: a/b/c, where a describes the input (arrival) process, b describes the service process, and c is the number of servers. Implicit in this description is the assumption that each arriving customer is assigned to a server immediately if one is available and holds that server for the length of time required (the ‘‘service time’’); if a server is not immediately available, the customer waits
Novel variants in growth differentiation factor 9 in mothers of dizygotic twins.

CONTEXT Genes from the ovarian bone morphogenetic signaling pathway (GDF9 and BMP15) are critical for normal human fertility. We previously identified a deletion mutation in GDF9 in sisters with spontaneous dizygotic (DZ) twins, but the prevalence of rare GDF9 variants in twinning families is unknown. OBJECTIVE The objective was to evaluate the frequency of rare variants in GDF9 in families with a history of DZ twinning. DESIGN AND SUBJECTS We recruited 3450 individuals from 915 DZ twinning families (1693 mothers of twins) and 1512 controls of Caucasian origin. One mother of DZ twins was selected from 279 of the 915 families, and a DNA sample was screened for rare variants in GDF9 using denaturant HPLC. Variants were confirmed by DNA sequencing and genotyped in the entire sample by matrix-assisted laser desorption ionization time of flight (MALDI-TOF) mass spectrometry. RESULTS We found two novel insertion/deletions (c.392-393insT, c.1268-1269delAA) and four missense alterations in the GDF9 sequence in mothers of twins. Two of the missense variants (c.307C > T, p.Pro103Ser and c.362C > T, p.Thr121Leu) were located in the pro-region of GDF9 and two (c.1121C > T, p.Pro374Leu and c.1360C > T, p.Arg454Cys) in the mature protein region. For each variant, the frequencies were higher in cases compared with controls. The proportion of mothers of DZ twins carrying any variant (4.12%) was significantly higher (P < 0.0001) than the proportion of carriers in controls (2.29%). CONCLUSION We describe new variants in the GDF9 gene that are significantly more common in mothers of DZ twins than controls, suggesting that rare GDF9 variants contribute to the likelihood of DZ twinning.
How to Design Optimistic Operations for Peer-to-Peer Replication

As collaboration over the Internet becomes an everyday affair, it is increasingly important to provide high quality of interactivity. Distributed applications can replicate collaborative objects at every site for the purpose of achieving high interactivity. Replication, however, has a fatal weakness that it is difficult to maintain consistency among replicas. This paper introduces operation commutativity as a key principle in designing operations in order to manage distributed replicas consistent. In addition, we suggest effective schemes that make operations commutative using the relations of objects and operations. Finally, we apply our approaches to some simple replicated abstract data types, and achieve their consistency without serialization and locking.
Running Head : Conscientiousness and OCPD Conscientiousness and Obsessive-Compulsive Personality Disorder

A dimensional perspective on personality disorder hypothesizes that the current diagnostic categories represent maladaptive variants of general personality traits. However, a fundamental foundation of this viewpoint is that dimensional models can adequately account for the pathology currently described by these categories. While most of the personality disorders have well established links to dimensional models that buttress this hypothesis, obsessive-compulsive personality disorder (OCPD) has obtained only inconsistent support. The current study administered multiple measures of 1) conscientiousness-related personality traits, 2) DSM-IV OCPD, and 3) specific components of OCPD (e.g., compulsivity and perfectionism) to a sample of 536 undergraduates who were oversampled for elevated OCPD scores. Six existing measures of conscientiousness-related personality traits converged strongly with each other supporting their assessment of a common trait. These measures of conscientiousness correlated highly with scales assessing specific components of OCPD, but obtained variable relationships with measures of DSM-IV OCPD. More specifically, there were differences within the conscientiousness instruments such that those designed to assess general personality functioning had small to medium relationships with OCPD, but those assessing more maladaptive variants obtained large effect sizes. These findings support the view that OCPD does represent a maladaptive variant of normal-range conscientiousness.
Children in Archaeological Lithic Analysis

One assumption that persists in the field of archaeology is that it is easier to observe children within historic sites through toys or burials than it is to observe children within a prehistoric setting through lithic production. The purpose of this paper is to examine the current position of children within the prehistoric archaeological literature and to provide case studies of research that focus specifically on how children can be observed within lithic analysis.
The Implementation of a Multiplexing Gold Code Generator using a Xilinx Logic Cell Array

This paper presents a novel system for generating, and switching between, a large number of Gold codes for use in a spread spectrum network. The underlying theory behind the choice of Gold codes is briefly discussed, and a method for reducing the amount of hardware required is introduced. The system is implemented using a Xilinx Logic Cell Array, and it is shown that use of a multiplexing arrangement can reduce the amount of hardware by a factor proportional to the number of transmitters in the network.
Some New Parallel Mechanisms Containing the Planar Four-Bar Parallelogram

A parallelogram allows the output link to remain at a fixed orientation with respect to an input link, for which it acts as a unique role in the design of parallel mechanisms. In this paper, the unique role of a parallelogram is used completely to design some new parallel mechanisms with two to six degrees of freedom (DoFs). In these mechanisms, some with three DoFs possess the advantage of very high rotational capability and some with two DoFs have the translational output of a rigid body. More than that, the design concept is also applied first to some parallel mechanisms to improve the systems' rotational capability. The parallel mechanisms proposed in this paper have wide applications in industrial robots, simulators, micromanipulators, parallel kinematics machines, and any other manipulation devices in which high rotational capability and stiffness are needed. Especially, the paper provides new concepts of the design of novel parallel mechanisms and the improvement of rotational capability for such systems.
Are retinal arteriolar or venular diameters associated with markers for cardiovascular disorders? The Rotterdam Study.

PURPOSE A lower retinal arteriolar-to-venular ratio (AVR) has been suggested to reflect generalized arteriolar narrowing and to predict the risk of cardiovascular diseases. The contribution of the separate arteriolar and venular diameters to this AVR is unknown. Thus, associations between retinal arteriolar and venular diameters, and the AVR on the one hand and blood pressure, atherosclerosis, inflammation markers, and cholesterol levels on the other were examined in the Rotterdam Study. METHODS In this cross-sectional population-based study, for one eye of each subject (> or =55 years; n = 5674), retinal arteriolar and venular diameters (in micrometers) of the blood columns were summed on digitized images. At baseline blood pressures, cholesterol levels, and markers of atherosclerosis and inflammation were also measured. RESULTS With increasing blood and pulse pressures, retinal arteriolar and venular diameters and the AVR decreased significantly and linearly. Lower arteriolar diameters were associated with increased carotid intima-media thickness. Larger venular diameters were associated with higher carotid plaque score, more aortic calcifications, lower ankle-arm index, higher leukocyte count, higher erythrocyte sedimentation rate, higher total serum cholesterol, lower HDL, higher waist-to-hip ratio, and smoking. A lower AVR was related to increased carotid intima-media thickness, higher carotid plaque score, higher leukocyte count, lower HDL, higher body mass index, higher waist-to-hip ratio, and smoking. CONCLUSIONS Because larger venular diameters are associated with atherosclerosis, inflammation, and cholesterol levels, the AVR does not depend only on generalized arteriolar narrowing due to the association between smaller arteriolar diameters and higher blood pressures. These data indicate that retinal venular diameters are variable and may play their own independent role in predicting cardiovascular disorders.
Incident prioritisation using analytic hierarchy process (AHP): Risk Index Model (RIM)

The landscape of security threats continues to evolve, with attacks becoming more serious and the number of vulnerabilities rising. For these threats to be managed, many security studies have been undertaken in recent years, mainly focusing on improving detection, prevention and response efficiency. This paper proposes an incident prioritisation model, the Risk Index Model (RIM), which is based on risk assessment and the analytic hierarchy process. For incidents to be prioritised, the model uses indicators, such as criticality, as decision factors to calculate incidents' risk index. The model also adopts different strategies to enhance the prioritisation process. To evaluate the model, two stages of evaluation study were conducted. The first stage aims to validate the model by comparing its results with the Common Vulnerability Scoring System and Snort. The second stage aims to enhance RIM by analysing the effect of using different strategies in the model. The experimental results in the first stage have shown that 100% of incidents could be rated with RIM, compared with only 17.23% with the Common Vulnerability Scoring System. The experiments in the second stage have shown significant changes in the resultant risk index as well as some of the top-priority incidents. Copyright © 2012 John Wiley & Sons, Ltd.
A Survey of Anonymous Blacklisting Systems

Anonymous communications networks, such as Tor, help to solve the real and important problem of enabling users to communicate privately over the Internet. However, by doing so, they also introduce an entirely new problem: How can service providers on the Internet allow anonymous access while protecting themselves against abuse by misbehaving anonymous users? Recent research efforts have proposed anonymous blacklisting systems (which are sometimes called anonymous revocation systems) to solve this problem. As opposed to revocable anonymity systems, which enable some trusted third party to deanonymize users, anonymous blacklisting systems provide users with a way to authenticate anonymously with a service provider (such as a website), while enabling the service provider to revoke access from any users that misbehave without revealing their identities. Unfortunately, although the various anonymous blacklisting systems are designed to solve similar problems, each operates under different assumptions and no unified security definitions exist. This paper proposes a formal definition for anonymous blacklisting systems, and a set of security and privacy properties that they should possess to protect: 1) users’ privacy against malicious service providers and third parties (including other malicious users), and 2) service providers against abuse by malicious users. We then propose a set of new performance requirements that should be satisfied to maximize any anonymous blacklisting system’s potential for real-world adoption, and provide formal definitions of some optional features already found in the literature on anonymous blacklisting systems. With especially close attention paid to the category we call Nymble-like systems, we give an overview of the anonymous blacklisting systems found in the literature.
Blocking artifacts reduction in block-based Dual-Tree Complex Wavelet transform

We propose a new method to reduce blocking artifacts in an encoded image by block-based Dual-Tree Complex Wavelet. In this paper, we describe a cause of blocking artifacts of the block-based approach and focus on a method for finding sparse representations from redundant complex coefficients. The proposed method offers minimal transform operation performing on the same resolution for an input image. Experimental results show that the proposed method reduces blocking artifacts that are observed along block boundaries and thus improves the visual quality.