Miracle-dz/UniFAR-FTUs huggingface dataset:
LlamaFur: learning latent category matrix to find unexpected relations in Wikipedia

Besides finding trends and unveiling typical patterns, modern information retrieval is increasingly interested in the discovery of serendipity and surprising information. In this work we focus on finding unexpected links in hyperlinked corpora when documents are assigned to categories. To achieve our goal, we determine a latent category matrix that explains common links using a highly scalable margin-based online learning algorithm, which makes us able to process graphs with 108 links in less than 10 minutes. We show that our method provides better accuracy than all existing text-based techniques, with higher efficiency and relying on a much smaller amount of information. It also provides higher precision than standard link prediction, especially at low recall levels; the two methods are in fact shown to be orthogonal to each other and can therefore be fruitfully combined.
The Duality of XML Markup and Programming Notation

In web projects it is often necessary to mix XML notation and program notation in a single document or program. In mono-lingual situations, the XML notation is either subsumed in the program or the program notation is subsumed in the XML document. As an introduction we analyze XML notation and programming notation in relation to each other. As the main contribution of the paper we describe a number of general issues to consider when subsuming XML in a given programming language.
Comparison therapeutic efficacy of underwater and overground walking training on the healthy subjects balancing ability

[Purpose] This study’s working hypothesis is that underwater walking training is beneficial for healthy subjects balance. [Subjects and Methods] Forty eight subjects (Underwater walking group=25, Overground walking group=23) completed the experiment. Healthy subjects with no orthopedic history of lower extremity injuries were recruited. Gait training is performed using the underwater treadmill consisted of 30-minute walking sessions, five times per week for four weeks. [Results] After the intervention, the medial-lateral and anterior-posterior balance indices increased significantly. [Conclusion] This study conducted underwater walking training on the healthy subjects, with positive effects on balancing ability.
Particle image velocimetry

Работа направлена на экспериментальное исследование турбулентной структуры течений при кавитационном обтекании одиночной пластины, гидрокрыла NACA0015 и каскада гидрокрыльев NACA0015. В результате измерений, проведенных методом PIV/LIF, были получены мгновенные поля скорости течения, и на их основе рассчитаны двумерные распределения средней скорости потока и всех статистических моментов турбулентных пульсаций скорости до третьего порядка включительно. В работе показано, что с уменьшением числа кавитации формирование турбулентного следа начинается выше по течению. При этом наблюдается значительное увеличение поперечных размеров следа, а также происходит интенсификация турбулентных пульсаций вследствие генерации крупномасштабных вихревых структур.
Graph structured views and their incremental maintenance

Studies the problem of maintaining materialized views of graph structured data. The base data consists of records containing identifiers of other records. The data could represent traditional objects (with methods, attributes and a class hierarchy), but it could also represent a lower-level data structure. We define simple views and materialized views for such graph structured data, analyzing options for representing record identity and references in the view. We develop incremental maintenance algorithms for these views.
Transvection mediated by the translocated cyclin D1 locus in mantle cell lymphoma

In mantle cell lymphoma (MCL) and some cases of multiple myeloma (MM), cyclin D1 expression is deregulated by chromosome translocations involving the immunoglobulin heavy chain (IgH) locus. To evaluate the mechanisms responsible, gene targeting was used to study long-distance gene regulation. Remarkably, these targeted cell lines lost the translocated chromosome (t(11;14)). In these MCL and MM cells, the nonrearranged cyclin D1 (CCND1) locus reverts from CpG hypomethylated to hypermethylated. Reintroduction of the translocated chromosome induced a loss of methylation at the unrearranged CCND1 locus, providing evidence of a transallelic regulatory effect. In these cell lines and primary MCL patient samples, the CCND1 loci are packaged in chromatin-containing CCCTC binding factor (CTCF) and nucleophosmin (NPM) at the nucleolus. We show that CTCF and NPM are bound at the IgH 3′ regulatory elements only in the t(11;14) MCL cell lines. Furthermore, NPM short hairpin RNA produces a specific growth arrest in these cells. Our data demonstrate transvection in human cancer and suggest a functional role for CTCF and NPM.
3 A ug 2 00 7 Predictability of band-limited and other processes

Pathwise predictability of continuous time processes is studied. We found that all band-limited processes are predictable in certain weak sense. More precisely, an integral over future time can be approximated by integrals over past time. The same result is obtained for processes being orthogonal to low-band processes, i.e., with zero energy at low frequencies. This result could be a useful addition to Nyquist-Shannon-Kotelnikov interpolation theorem. For processes of the general kind, we found that the similar predictability can have place in models where a low-pass ideal filter exists.
A traffic jam prediction device and method

The present invention provides a road environment even when it is possible to predict the traffic congestion changes apparatus and methods. The latest of which is the current traffic congestion information and changes in the traffic jam information from the previous estimate based on the current traffic status. It predicted the current level of traffic congestion based on the latest traffic congestion information and the current traffic status. This result can be used in a conventional navigation method and apparatus for driving route of the vehicle design.
Canevas logiciel pour la construction d'infrastructures logicielles dynamiquement adaptables

La construction d'infrastructures logicielles adaptables a fait l'objet de nombreux travaux de recherche au cours des dernieres annees. Cependant, dans le nouvel environnement de traitement global de l'information, caracterise par une grande taille et par une nature tres dynamique, les systemes existants presentent des limitations certaines. Les mecanismes utilises pour la composition et l'adaptation sont effectivement figes et restreints dans leurs possibilites d'evolution. Dans cette these, nous entendons lever ces limitations en proposant un modele de composition et un modele d'adaptation, bases sur un jeu complet d'interfaces facultatives. Nous suivons une approche minimale, afin de rendre les deux modeles proposes accessibles a la construction d'infrastructures logicielles "a la carte". Par ailleurs, nous montrons que ces modeles sont directement implantables et utilisables pour la construction de systemes. Nous avons realise un generateur de composants reconfigurables, nomme GReC, reposant sur ces modeles, dont l'objectif est de simplifier la tâche du developpeur d'infrastructures adaptables. Deux experiences menees dans le cadre des reseaux actifs valident l'interet de la demarche et montrent l'apport de GReC en matiere d'adaptabilite.
Contemporary Role of Testis Sparing Surgery: A Systematic Review

Testis-sparing surgery (TSS) represents a therapeutic choice for testicular cancer (TC). However, international guidelines are very cautious about the use of the testis-sparing technique, namely due to the lack of certain indications and long-term oncological outcomes. The aim of this systematic-review is to illustrate current trends of what may today be the uses of organ-sparing surgery in TC, to evaluate the relationship between the organ-sparing safety and oncological features such as definitive histology, tumour size, and post-surgery oncological outcomes. This analysis was conducted according to the Preferred Reporting Items for Systematic Reviews and Meta-analysis guidelines. An electronic search of the Medline and Embase was undertaken until September 2014. The search was limited to English-Language articles. Current indications of TSS are synchronous bilateral testicular tumours, metachronous contralateral tumours, or tumour in a solitary testis with normal preoperative testosterone levels. Moreover, histological characteristics should not be taken into account when performing a TSS approach. TSS outcomes for germ cell tumours are encouraging and we reported high rates of disease-free survival and a few cases of patients receiving neoadjuvant chemotherapy or radiotherapy. In light of the examined, TSS could be considered a viable alternative to radical surgery of the testis but it should be performed in specialised centres with competence.
MOVING OBJECT DETECTION USING BACKGROUND SUBTRACTION ALGORITHM USING SIMULINK

Background subtraction methods are widely exploited for moving object detection in videos in many applications, such as traffic monitoring, human motion capture and video surveillance. How to correctly and efficiently model and update the background model and how to deal with shadows are two of the most distinguishing and challenging aspects of such approaches. This work proposes a general-purpose method which combines statistical assumptions with the object-level knowledge of moving objects, apparent objects (ghosts) and shadows acquired in the processing of the previous frames. Pixels belonging to moving objects, ghosts and shadows are processed differently in order to supply an object-based selective update. The proposed approach exploits gray color information for both background subtraction to improve object segmentation. The approach proves fast, flexible and precise in terms of pixel accuracy. The implementation of the background subtraction algorithm is done in two domains code is written in Matlab, then using Simulink blocks sets.
Growth overshoot and seasonal size changes in the skulls of two weasel species

Ontogenetic changes in mammalian skulls are complex. For a very few species (i.e. some Sorex shrews), these also include seasonally driven, bidirectional size changes within individuals, presumably to reduce energy requirements during low resource availabilities. These patterns are poorly understood, but are likely most pronounced in high-metabolic species with limited means for energy conservation. We used generalized additive models to quantify the effect of location, Julian day, age and sex on the length and depth of 512 and 847 skulls of stoat (Mustela erminea) and weasel (M. nivalis) specimens collected throughout the northern hemisphere. Skull length of both species varies between sexes and geographically, with stoat skull length positively correlated with latitude. Both species demonstrate seasonal and ontogenetic patterns, including a rare, absolute growth overshoot in juvenile braincase depth. Standardized braincase depths of both species peak in their first summer, then decrease in their first winter, followed by a remarkable regrowth that peaks again during their second summer. This seasonal pattern varies in magnitude and timing between geographical regions and the sexes, matching predictions of Dehnel's phenomenon. This suggests implications for the evolution of over-wintering strategies in mammals, justifying further research on their mechanisms and value, with implications for applied osteology research.
Inferring quantitative models of regulatory networks from expression data

MOTIVATION Genetic networks regulate key processes in living cells. Various methods have been suggested to reconstruct network architecture from gene expression data. However, most approaches are based on qualitative models that provide only rough approximations of the underlying events, and lack the quantitative aspects that are critical for understanding the proper function of biomolecular systems. RESULTS We present fine-grained dynamical models of gene transcription and develop methods for reconstructing them from gene expression data within the framework of a generative probabilistic model. Unlike previous works, we employ quantitative transcription rates, and simultaneously estimate both the kinetic parameters that govern these rates, and the activity levels of unobserved regulators that control them. We apply our approach to expression datasets from yeast and show that we can learn the unknown regulator activity profiles, as well as the binding affinity parameters. We also introduce a novel structure learning algorithm, and demonstrate its power to accurately reconstruct the regulatory network from those datasets.
Guideline-Based Evaluation of Web Readability

Effortless reading remains an issue for many Web users, despite a large number of readability guidelines available to designers. This paper presents a study of manual and automatic use of 39 readability guidelines in webpage evaluation. The study collected the ground-truth readability for a set of 50 webpages using eye-tracking with average and dyslexic readers (n = 79). It then matched the ground truth against human-based (n = 35) and automatic evaluations. The results validated 22 guidelines as being connected to readability. The comparison between human-based and automatic results also revealed a complex framework: algorithms were better or as good as human experts at evaluating webpages on specific guidelines - particularly those about low-level features of webpage legibility and text formatting. However, multiple guidelines still required a human judgment related to understanding and interpreting webpage content. These results contribute a guideline categorization laying the ground for future design evaluation methods.
N-Glycosylation of Fibroblast Growth Factor Receptor 1 Regulates Ligand and Heparan Sulfate Co-receptor Binding*

The regulation of cell function by fibroblast growth factors (FGF) occurs through a dual receptor system consisting of a receptor-tyrosine kinase, FGFR and the glycosaminoglycan heparan sulfate (HS). Mutations of some potential N-glycosylation sites in human fgfr lead to phenotypes characteristic of receptor overactivation. To establish how N-glycosylation may affect FGFR function, soluble- and membrane-bound recombinant receptors corresponding to the extracellular ligand binding domain of FGFR1-IIIc were produced in Chinese Hamster Ovary cells. Both forms of FGFR1-IIIc were observed to be heavily N-glycosylated and migrated on SDS-PAGE as a series of multiple bands between 50 and 75 kDa, whereas the deglycosylated receptors migrated at 32 kDa, corresponding to the expected molecular weight of the polypeptides. Optical biosensor and quartz crystal microbalance-dissipation binding assays show that the removal of the N-glycans from FGFR1-IIIc caused an increase in the binding of the receptor to FGF-2 and to heparin-derived oligosaccharides, a proxy for cellular HS. This effect is mediated by N-glycosylation reducing the association rate constant of the receptor for FGF-2 and heparin oligosaccharides. N-Glycans were analyzed by mass spectrometry, which demonstrates a predominance of bi- and tri-antennary core-fucosylated complex type structures carrying one, two, and/or three sialic acids. Modeling of such glycan structures on the receptor protein suggests that at least some may be strategically positioned to interfere with interactions of the receptor with FGF ligand and/or the HS co-receptor. Thus, the N-glycans of the receptor represent an additional pathway for the regulation of the activity of FGFs.
Diltiazem increases late-onset congestive heart failure in postinfarction patients with early reduction in ejection fraction. The Adverse Experience Committee; and the Multicenter Diltiazem Postinfarction Research Group.

The Multicenter Diltiazem Postinfarction Trial (MDPIT) reported no consistent diltiazem effect on new or worsened congestive heart failure (CHF) during 12-52 months' follow-up after acute myocardial infarction. This was puzzling in light of the observation that patients with findings suggesting left ventricular dysfunction (LVD) at baseline on diltiazem had more cardiac events (cardiac mortality or recurrent nonfatal infarction) than such patients on placebo. We hypothesized that diltiazem increased the frequency of late CHF as well as of cardiac events, but only in patients predisposed by LVD. Using the same characterizing variables as the primary MDPIT analysis, we found that patients with pulmonary congestion, anterolateral Q wave infarction, or reduced ejection fraction (EF) at baseline were more likely to have CHF during follow-up than those without these markers of LVD. CHF was particularly frequent in the patients with LVD who were randomized to diltiazem. Among those with a baseline EF of less than 0.40, late CHF appeared in 12% (39/326) receiving placebo and 21% (61/297) receiving diltiazem (p = 0.004). Life table analysis in patients with an EF of less than 0.40 confirmed more frequent late CHF in those taking diltiazem (p = 0.0017). In addition, the diltiazem-associated rise in the frequency of late CHF was progressively greater with increasingly severe decrements in baseline EF. This diltiazem effect was absent in patients with pulmonary congestion at baseline but an EF of 0.40 or more, suggesting a unique association between diltiazem-related late CHF and systolic LVD. (ABSTRACT TRUNCATED AT 250 WORDS)
Access and utilization of HIV treatment and services among women sex workers in Vancouver’s downtown eastside

Many HIV-infected women are not realizing the benefits of highly active antiretroviral therapy (HAART) despite significant advancements in treatment. Women in Vancouver’s Downtown Eastside (DTES) are highly marginalized and struggle with multiple morbidities, unstable housing, addiction, survival sex, and elevated risk of sexual and drug-related harms, including HIV infection. Although recent studies have identified the heightened risk of HIV infection among women engaged in sex work and injection drug use, the uptake of HIV care among this population has received little attention. The objectives of this study are to evaluate the needs of women engaged in survival sex work and to assess utilization and acceptance of HAART. During November 2003, a baseline needs assessment was conducted among 159 women through a low-threshold drop-in centre servicing street-level sex workers in Vancouver. Cross-sectional data were used to describe the sociodemographic characteristics, drug use patterns, HIV/hepatitis C virus (HCV) testing and status, and attitudes towards HAART. High rates of cocaine injection, heroin injection, and smokeable crack cocaine use reflect the vulnerable and chaotic nature of this population. Although preliminary findings suggest an overall high uptake of health and social services, there was limited attention to HIV care with only 9% of the women on HAART. Self-reported barriers to accessing treatment were largely attributed to misinformation and misconceptions about treatment. Given the acceptability of accessing HAART through community interventions and women specific services, this study highlights the potential to reach this highly marginalized group and provides valuable baseline information on a population that has remained largely outside consistent HIV care.
TWO FACES OF SIGN: ICONIC AND ABSTRACT *

In this paper, we show that the total range of the communication system of the deaf is considerably enriched but at the same time rendered more difficult to analyze, because pantomime and other spontaneous nonsign representations occur in the same mode as regular ASL signs in deaf discourse. We note that the rarification of what was originally nonsign depiction is clearly an important source of regular ASL signs. We show that criteria can be established that would distinguish the clear cases of pantomime from the regular ASL signs. Nonetheless, there remain a sizable number of regular ASL signs which, although they are neither pantomimic nor otherwise freely mimetic, still appear to retain an iconic cast. We show that very few ASL signs are actually transparent; that is, a nonsigner cannot guess the meaning of a sign in the absence of further information. On the other hand, many signs are iconic in the sence that nonsigners, when given the sign and its meaning, show considerable agreement in how the two are related. More important in terms of language and its users is the significance of iconicity for deaf signers themselves. This paper shows that while in special circumstances the deaf do play on iconic elements of certain signs for special effects, iconicity plays no observable role in the coding of signs in short-term memory. The abstract formational parameters definitely dominate. We further note that it is the abstract system and not purely iconic aspects that have determined observed historical changes in the form of ASL signs. We interpret this as indicating the deeper structural significance of the abstract formational level. Finally, we show that very widespread and productive grammatical processes, especially suited for a visual-gestural language, override the iconic aspects of signs also at the synchronic structural level.
Involvement of Wnt signaling in the injury of murine mesenchymal stem cells exposed to X-radiation

Abstract Purpose: To investigate the injury of murine mesenchymal stem cells (mMSC) exposed to 4 Gy X-radiation and the role of canonical and non-canonical wingless-type (Wnt) signaling in the radiation injury. Materials and methods: C3H10T1/2 cells were submitted to 4 Gy X-radiation. At different time points after radiation, Hoechst33258 staining and Annexin V-fluorescein isothiocyanate (FITC) flow cytometry analysis were performed to assess cellular apoptosis. Senescence-associated β-galactosidase (SA-β-gal) staining was performed to analyze cellular senescence. Cell cycle was measured by flow cytometry. P53, p21, Wnt3a, Wnt5a, sonic hedgehog (Shh) mRNA was detected by Real time polymerase chain reaction (PCR) and Wnt5a protein was determined by Western blot. Results: A time-dependent cellular apoptosis was observed with a peak level 12 hours after radiation. Cellular senescence was detected 72 h after radiation. A remarkable up-regulation of Wnt5a mRNA expression (∼ 269-fold) and protein expression was seen 72 h after radiation. Conclusions: The effect of 4 Gy X-radiation to mMSC was time-dependent in the form of cellular apoptosis in the early period and cellular senescence in the late period. Non-canonical Wnt signaling may be involved in mMSC senescence induced by 4 Gy X-radiation.
Using Trusted Execution Environments in Two-factor Authentication: comparing approaches

Classic two-factor authentication has been around for a long time and has enjoyed success in certain markets (such as the corporate and the banking environ- ment). A reason for this success are the strong security properties, particularly where user interaction is concerned. These properties hinge on a security token being a physi- cally separate device. This paper investigates whether Trusted Execution Environments (TEE) can be used to achieve a comparable level of security without the need to have a separate device. To do this, we introduce a model that shows the security properties of user interaction in two-factor authentication. The model is used to examine two TEE technologies, Intel’s IPT and ARM TrustZone, revealing that, although it is possible to get close to classic two-factor authentication in terms of user interaction security, both technologies have distinct drawbacks. The model also clearly shows an open problem shared by many TEEs: how to prove to the user that they are dealing with a trusted application when trusted and untrusted applications share the same display.