Miracle-dz/UniFAR-FTUs huggingface dataset:
Structure of Extruded Fibers and Films Prepared from Nylon 6-Clay Hybrid

Nylon 6-clay hybrid (NCH) was a nanocomposite consisting of nylon 6 and montmorillonite; the silicate layers of montmorillonite were well dispersed individually in the matrix of nylon 6. Five extruded strands with different clay contents and films were prepared. The structures of the NCH extrudates and NCH films were investigated by wide angle and small angle scattering methods. In NCH extrudates, silicate layers were oriented along the extrusion direction and the fiber axis of the γ-type crystallites of nylon 6 was oriented perpendicular to the extrusion direction. In NCH films, not only the hydrogen-bonded sheets of nylon 6 crystallites but also the surface of the silicate layer were found to be parallel to the film surface. Such preferred orientations of the silicate layer and the nylon 6 crystallites suggested the presence of an interaction between them. This interaction hindered the crystal transformation from γ to α types, which took place during the heat treatment and drawing process.
Mechanisms imposing the Vβ bias of Vα14 natural killer T cells and consequences for microbial glycolipid recognition

Mouse and human natural killer T (NKT) cells recognize a restricted set of glycosphingolipids presented by CD1d molecules, including self iGb3 and microbial α-glycuronosylceramides. The importance of the canonical Vα14-Jα18 TCR α chain for antigen recognition by NKT cells is well recognized, but the mechanisms underlying the Vβ8, Vβ7, and Vβ2 bias in mouse have not been explored. To study the influences of thymic selection and the constraints of pairing with Vα14-Jα18, we have created a population of mature T cells expressing Vα14-Jα18 TCR α chain in CD1d-deficient mice and studied its recognition properties in vitro and in vivo. Transgenic cells expressed a diverse Vβ repertoire but their recognition of endogenous ligands and synthetic iGb3 was restricted to the same biased Vβ repertoire as expressed in natural NKT cells. In contrast, α-GalCer, a synthetic homologue of microbial α-glycuronosylceramides, was recognized by a broader set of Vβ chains, including the biased NKT set but also Vβ6, Vβ9, Vβ10, and Vβ14. These surprising findings demonstrate that, whereas Vβ8, Vβ7, and Vβ2 represent the optimal solution for recognition of endogenous ligand, many Vβ chains that are potentially useful for the recognition of foreign lipids fail to be selected in the NKT cell repertoire.
THE FRESHWATER CYANOBACTERIUM PLANKTOTHRIX SP. FP1: MOLECULAR IDENTIFICATION AND DETECTION OF PARALYTIC SHELLFISH POISONING TOXINS

A filamentous cyanobacterium, belonging to the Order of Oscillatoriales, was found to be responsible for a toxic algal bloom in Lake Varese, Italy, during the summer of 1997. Morphological characters, as well as near complete 16S rRNA gene sequencing, revealed that the dominant species of the bloom was most closely related to the genus Planktothrix. In addition, genetic analysis of the phycocyanin operon of Planktothrix sp. FP1 revealed a novel primary structure, previously undescribed within the cyanobacteria, which was used as a genetic marker for rapid detection and identification of this toxic strain. The occurrence of saxitoxin (STX), a principal toxin in paralytic shellfish poisoning (PSP), was confirmed in the natural bloom sample by both pre‐column and post‐column derivatization high‐performance liquid chromatography (HPLC) analyses, and eventually by liquid chromatography/mass spectrometry (LC/MS). The toxicity of this field sample was also revealed by electrophysiological assays in which the extract inhibited 90% of the voltage‐dependent Na+ current in human neuroblastoma cells at the STX concentration of 80 nM. The cultured strain showed a lower physiologic activity than the bloom sample (67% blockage of Na+ current at a toxin concentration of 200 nM), and STX was detected only by pre‐column HPLC, indicating the presence of a compound structurally close to STX. Chemical and molecular genetic analyses performed here add Planktothrix sp. FP1 to the growing list of diverse cyanobacterial species capable of synthesizing STX and its related compounds.
Relation between Health Literacy Levels, Hypertension Awareness and Control among Primary-secondary School Teachers in Turkey

Objective Health literacy plays a critical role in chronic disease self-management. This study aimed to determine the relation between health literacy levels, hypertension awareness and control among primary-secondary school teachers in Turkey. Materials and Methods This descriptive and cross-sectional research was conducted among school teachers with the participation of 500 volunteer teachers of both genders. The response rate was 86.2%. To determine health literacy levels, the Newest Vital Sign Scale and Blood Pressure Concept Test were used. Results The mean scores of all individuals were 2.12 ± 1.82 over six points although this showed “limited” levels of health literacy. The mean scores obtained from the scale were 2.13 ± 1.83 in non-hypertensives, while it was 2.06 ± 1.77 in hypertensives. Nonetheless, disease knowledge and awareness were low in teachers. Adequate health literacy levels were low according to disease awareness and control. The measured health literacy levels of teachers didn't overlap with their own assessments about health literacy skills. Recommendations Limited health literacy levels in educators gave an impression that our education system was poor in terms of health education programs.
Postoperative Pain Experience: Results from a National Survey Suggest Postoperative Pain Continues to Be Undermanaged

Postoperative pain can have a significant effect on patient recovery. An understanding of patient attitudes and concerns about postoperative pain is important for identifying ways health care professionals can improve postoperative care. To assess patients’ postoperative pain experience and the status of acute pain management, we conducted a national study by using telephone questionnaires. A random sample of 250 adults who had undergone surgical procedures recently in the United States was obtained from National Family Opinion. Patients were asked about the severity of postsurgical pain, treatment, satisfaction with pain medication, patient education, and perceptions about postoperative pain and pain medications. Approximately 80% of patients experienced acute pain after surgery. Of these patients, 86% had moderate, severe, or extreme pain, with more patients experiencing pain after discharge than before discharge. Experiencing postoperative pain was the most common concern (59%) of patients. Almost 25% of patients who received pain medications experienced adverse effects; however, almost 90% of them were satisfied with their pain medications. Approximately two thirds of patients reported that a health care professional talked with them about their pain. Despite an increased focus on pain management programs and the development of new standards for pain management, many patients continue to experience intense pain after surgery. Additional efforts are required to improve patients’ postoperative pain experience.
Effect of Bottle Storage on Colour, Phenolics and Volatile Composition of Malvasia and Moscato White Wines

The effect of bottle storage on the colour, phenolics and volatile composition of Malvasia and Muscat wines obtained from grapes grown in Sardinia was evaluated. Colour was evaluated by UV-VIS spectrophotometry and by tristimulus colorimetry. Polyphenols were analysed by UV-VIS spectrophotometry and HPLCDAD. GC/MS was used to identify and quantify the content of free and bound volatile compounds. As expected, the absorbance values at 420 nm increased significantly for both wines during storage, due to oxidative browning, while difference in colour (DE*) from the beginning of storage and after 18 months was more intense in the Muscat wine than in the Malvasia wine. A significant decrease was observed in different phenolic compounds over time, especially in the Malvasia wine. In-bottle storage for 18 months at 20°C in the dark resulted in a significant decrease in all the classes of free and bound volatiles. These finding enhance knowledge regarding the effects of bottle storage on Muscat and Malvasia wines. This is of interest because, rather surprisingly, this topic has been poorly investigated in relation to these two varieties.
FPGA based image processing for optical surface inspection with real time constraints

Today, high-quality printing products like banknotes, stamps, or vouchers, are automatically checked by optical surface inspection systems. In a typical optical surface inspection system, several digital cameras acquire the printing products with fine resolution from different viewing angles and at multiple wavelengths of the visible and also near infrared spectrum of light. The cameras deliver data streams with a huge amount of image data that have to be processed by an image processing system in real time. Due to the printing industry’s demand for higher throughput together with the necessity to check finer details of the print and its security features, the data rates to be processed tend to explode. In this contribution, a solution is proposed, where the image processing load is distributed between FPGAs and digital signal processors (DSPs) in such a way that the strengths of both technologies can be exploited. The focus lies upon the implementation of image processing algorithms in an FPGA and its advantages. In the presented application, FPGAbased image-preprocessing enables real-time implementation of an optical color surface inspection system with a spatial resolution of 100 μm and for object speeds over 10 m/s. For the implementation of image processing algorithms in the FPGA, pipeline parallelism with clock frequencies up to 150 MHz together with spatial parallelism based on multiple instantiations of modules for parallel processing of multiple data streams are exploited for the processing of image data of two cameras and three color channels. Due to their flexibility and their fast response times, it is shown that FPGAs are ideally suited for realizing a configurable all-digital PLL for the processing of camera line-trigger signals with frequencies about 100 kHz, using pure synchronous digital circuit design.
Heat Loss May Explain Bill Size Differences between Birds Occupying Different Habitats

Background Research on variation in bill morphology has focused on the role of diet. Bills have other functions, however, including a role in heat and water balance. The role of the bill in heat loss may be particularly important in birds where water is limiting. Song sparrows localized in coastal dunes and salt marsh edge (Melospiza melodia atlantica) are similar in size to, but have bills with a 17% greater surface area than, those that live in mesic habitats (M. m. melodia), a pattern shared with other coastal sparrows. We tested the hypotheses that sparrows can use their bills to dissipate “dry” heat, and that heat loss from the bill is higher in M. m. atlantica than M. m. melodia, which would indicate a role of heat loss and water conservation in selection for bill size. Methodology/Principal Findings Bill, tarsus, and body surface temperatures were measured using thermal imaging of sparrows exposed to temperatures from 15–37°C and combined with surface area and physical modeling to estimate the contribution of each body part to total heat loss. Song sparrow bills averaged 5–10°C hotter than ambient. The bill of M. m atlantica dissipated up to 33% more heat and 38% greater proportion of total heat than that of M. m. melodia. This could potentially reduce water loss requirements by approximately 7.7%. Conclusions/Significance This >30% higher heat loss in the bill of M. m. atlantica is independent of evaporative water loss and thus could play an important role in the water balance of sparrows occupying the hot and exposed dune/salt marsh environments during the summer. Heat loss capacity and water conservation could play an important role in the selection for bill size differences between bird populations and should be considered along with trophic adaptations when studying variation in bill size.
Optimizing countershading camouflage

Significance Because the sun and sky are above us, natural illumination is directional and the cues from shading reveal shape and depth. However, many animals are darker on their backs and, over 100 years ago, it was proposed that this phenomenon was camouflage: countering the cues to shape that directional illumination creates. However, does this camouflage work in practice? We predicted the optimal countershading for different lighting conditions and tested this possibility with correspondingly patterned model “caterpillars” predated by birds in the wild. Predation rates varied with coloration and lighting in exactly the manner predicted. Such subtlety in the effects of countershading vindicates conclusions from prior evidence demonstrating stronger countershading in animals in more brightly lit habitats. Countershading, the widespread tendency of animals to be darker on the side that receives strongest illumination, has classically been explained as an adaptation for camouflage: obliterating cues to 3D shape and enhancing background matching. However, there have only been two quantitative tests of whether the patterns observed in different species match the optimal shading to obliterate 3D cues, and no tests of whether optimal countershading actually improves concealment or survival. We use a mathematical model of the light field to predict the optimal countershading for concealment that is specific to the light environment and then test this prediction with correspondingly patterned model “caterpillars” exposed to avian predation in the field. We show that the optimal countershading is strongly illumination-dependent. A relatively sharp transition in surface patterning from dark to light is only optimal under direct solar illumination; if there is diffuse illumination from cloudy skies or shade, the pattern provides no advantage over homogeneous background-matching coloration. Conversely, a smoother gradation between dark and light is optimal under cloudy skies or shade. The demonstration of these illumination-dependent effects of different countershading patterns on predation risk strongly supports the comparative evidence showing that the type of countershading varies with light environment.
Electronic Patient Reported Outcomes in Paediatric Oncology - Applying Mobile and Near Field Communication Technology

BACKGROUND Electronic Patient Reported Outcomes (ePRO) gathered using telemonitoring solutions might be a valuable source of information in rare cancer research. OBJECTIVES The objective of this paper was to develop a concept and implement a prototype for introducing ePRO into the existing neuroblastoma research network by applying Near Field Communication and mobile technology. METHODS For physicians, an application was developed for registering patients within the research network and providing patients with an ID card and a PIN for authentication when transmitting telemonitoring data to the Electronic Data Capture system OpenClinica. For patients, a previously developed telemonitoring system was extended by a Simple Object Access Protocol (SOAP) interface for transmitting nine different health parameters and toxicities. RESULTS The concept was fully implemented on the front-end side. The developed application for physicians was prototypically implemented and the mobile application of the telemonitoring system was successfully connected to OpenClinica. Future work will focus on the implementation of the back-end features.
Barriers to and Correlates of Retention in Behavioral Health Treatment Among Latinos in 2 Different Host Countries: The United States and Spain

Context: Latino immigrants constitute a large portion of the Spanish and US immigrant populations, yet a dearth of research exists regarding barriers to retention in behavioral health care. Objectives: To identify and compare perceived barriers related to behavioral health care among first- and second-generation Latinos in Boston, Madrid, and Barcelona, and evaluate whether the frequency of behavioral health care use in the last year was related to these barriers. Design, Setting, and Participants: Data were obtained from the International Latino Research Partnership project. First- or second-generation self-identified Latino immigrants aged 18 years and more who resided more than 1 year in the host country were recruited from community agencies and primary care, mental health, substance abuse, and HIV clinics. Main Outcome Measures: Eleven barriers were assessed and compared across sites. The relationship between barriers and behavioral services visits within the last year was evaluated, adjusting for sociodemographics, clinical measures, degree of health literacy, cultural, and social factors. Results: Wanting to handle the problem on one's own, thinking that treatment would not work, and being unsure of where to go or who to see were the most frequently reported barriers for Latino immigrants. Previous treatment failure, difficulties in transportation or scheduling, and linguistic barriers were more likely to be reported in Boston; trying to deal with mental health problems on one's own was more commonly reported in Barcelona and Madrid. Two barriers associated with the number of visits were concerns about the cost of services and uncertainty about where to go or who to see. Conclusions: After adjusting for sociodemographics, clinical measures, degree of health literacy, cultural, and social factors, barriers still differed significantly across sites. Efforts to improve behavioral health services must be tailored to immigrants' context, with attention to changing attitudes of self-reliance and outreach to improve access to and retention in care.
Preparation of Self‐Organized Mesoscale Polymer Patterns on a Solid Substrate: Continuous Pattern Formation from a Receding Meniscus

Regular polymer patterns are formed from casting a dilute polymer solution on a solid substrate. Dissipative structures, e.g., convection patterns, fingering instabilities, and so on, are formed in the evaporation process of casting polymer films. Controlled production and manufacturing of patterned polymer films can be achieved when the evaporating solution edge, especially the meniscus region on the casting substrate, is formed under controlled casting conditions. In this report, we describe a computer‐controlled apparatus which has two precisely manipulated sliding glass plates. A narrow, thin liquid film of polymer solution with a receding meniscus is continuously supplied from a small gap between two glass plates (one sliding and the other stationary), and a patterned polymer film is subsequently formed on the stationary substrate from the evaporating solution edge. Several types of polymer patterns from various polymers are reproducibly prepared by changing preparation conditions such as sliding speed and polymer concentration.
Etude de la formation de débris d'usure dans la pro thèse totale de hanche par un modèle numérique particulaire

Ultra-High Molecular Weight Polyethylene (UHMWPE) wdebris has been recognized as the one of the main causes of aseptic loosening in total hi p replacement. The experimental work of Cooper has confirmed the general theory of abrasive and adhesi ve wear for UHMWPE at a microscopic level in joint replacement. In addition to the different operating conditions, such as normal load and sliding veloci ty, abrasive wear mechanisms are related to the angular ity of the abrasive wear particles or microscopic asperity. The goal of the present study is to analy ze the effect of the asperity geometry on abrasive wear mechanisms as well as wear particle formation. Our study consists in numerical simulation of a rigid asperity sliding against the UHMWPE surface using t he so-called Smoothed Particle Hydrodynamics (SPH) method. Mots-clefs : abrasion, UHMWPE, SPH
A bioabsorbable membrane (Seprafilm®) may prevent postoperative mediastinal adhesions following mediastinoscopy: an experimental study in rats.

INTRODUCTION The aim of this experimental study was to investigate the anti-adhesion property of a bioabsorbable membrane following mediastinoscopy in a rat model. METHODS The study was conducted in 20 male Sprague-Dawley rats. Mediastinoscopy was performed all of them. Rats were divided into two groups; control group (n=10); mediastinoscopy alone, study group (n=10); mediastinoscopy and sodiumhyaluronate-carboxymethlycellulose film (Seprafilm®; Genzyme Corporation, Cambridge, Mass. USA). It was used to the mediastinal surface at the end of the surgical procedure in study group. Re-mediastinoscopy was performed after 7 days. Adhesion and vascularity grade description scores were analyzed. The parameters evaluated were presence of polymorhphonucleer leucocyte, macrophage, lymphocyte, fibroblasts, edema, neovascularisation, collagenisation, and foreing body reaction. RESULTS All the rats survived uneventfully until being sacrificed without any postoperative complications. The mean adhesion score was found to be significantly higher in control group (n=2.5±0.5) compared with study group (n=1.0±0.1) (P=0.007). Vascularity grade description score was significantly higher in control group (n=2.3±0.6) than in study group (n=1.4±0.6) (P=0.009). There were no statistical differences between the groups with regard to edema, lymphocyte and macrophage infiltration, fibroblast proliferation and foreign body reactions (P>0.05). CONCLUSION The used of Seprafilm® during the primary procedure can reduce to the mediastinal adhesions. However, further studies are required to assess the precise impact of the anti-adhesive agents on adhesion.
Secure Arithmetic Coding Using Interval Splitting

We present a modified approach to arithmetic coding in which the overall length within the range (0, 1) allocated to each symbol is preserved, but the traditional assumption that a single contiguous interval is used for each symbol is removed. A key known to both the encoder and decoder is used to describe where the intervals are "split" prior to encoding each new symbol. The repeated splitting has the effect of both scrambling the intervals and altering their lengths, thereby allowing both encryption and compression to be obtained simultaneously.
Identification and Structural Characterization of a New Three-Finger Toxin Hemachatoxin from Hemachatus haemachatus Venom

Snake venoms are rich sources of biologically active proteins and polypeptides. Three-finger toxins are non-enzymatic proteins present in elapid (cobras, kraits, mambas and sea snakes) and colubrid venoms. These proteins contain four conserved disulfide bonds in the core to maintain the three-finger folds. Although all three-finger toxins have similar fold, their biological activities are different. A new three-finger toxin (hemachatoxin) was isolated from Hemachatus haemachatus (Ringhals cobra) venom. Its amino acid sequence was elucidated, and crystal structure was determined at 2.43 Å resolution. The overall fold is similar to other three-finger toxins. The structure and sequence analysis revealed that the fold is maintained by four highly conserved disulfide bonds. It exhibited highest similarity to particularly P-type cardiotoxins that are known to associate and perturb the membrane surface with their lipid binding sites. Also, the increased B value of hemachotoxin loop II suggests that loop II is flexible and may remain flexible until its interaction with membrane phospholipids. Based on the analysis, we predict hemachatoxin to be cardiotoxic/cytotoxic and our future experiments will be directed to characterize the activity of hemachatoxin.