Miracle-dz/UniFAR-FTUs huggingface dataset:
RECONHECIMENTO DE ATIVOS INTANGÍVEIS: UMA ANÁLISE SOBRE O VALUE RELEVANCE NO BRASIL

O objetivo do artigo foi analisar a influencia dos ativos intangiveis reconhecidos apos a adocao obrigatoria das International Financial Reporting Standards (IFRS) e a relevância da informacao contabil no mercado de capitais brasileiro. O estudo iniciou-se a partir da identificacao dos trabalhos ja feitos sobre o tema em outros paises, e justifica-se pela importância da abordagem do value relevance apos a adocao das IFRS em um mercado de capitais emergente. O procedimento metodologico caracteriza a pesquisa como descritiva, com uso de tecnica estatistica por meio de testes de correlacao de Pearson e regressao multipla para a analise dos resultados. Na amostra foram selecionados dados trimestrais das 100 empresas nao financeiras mais liquidas listadas na BM&FBovespa, no periodo de 2010 a 2012. No resultado evidencia-se que ha relacao positiva e significativa entre os valores identificados dos ativos intangiveis reconhecidos e o valor de mercado. No entanto, nao ha relacao significativa com o reconhecimento do goodwill.
Real-time endobronchial ultrasound-guided transbronchial needle aspiration of mediastinal and hilar lymph nodes.

STUDY OBJECTIVES Although various techniques are available for obtaining pathology specimens from the mediastinal lymph nodes, including conventional bronchoscopic transbronchial needle aspiration (TBNA), transesophageal ultrasonography-guided needle aspiration, and mediastinoscopy, there are limitations to these techniques, which include low yield, poor access, need for general anesthesia, or complications. To overcome these problems, we undertook the current study to evaluate the clinical utility of the newly developed ultrasound puncture bronchoscope to visualize and perform real-time TBNA of the mediastinal and hilar lymph nodes under direct endobronchial ultrasonography (EBUS) guidance. DESIGN Prospective patient enrollment. SETTING University teaching hospital. PATIENTS From March 2002 to September 2003, 70 patients were included in the study. INTERVENTIONS The new convex probe (CP) EBUS is integrated with a convex scanning probe on its tip with a separate working channel, thus permitting real-time EBUS-guided TBNA. The indications for CP-EBUS were the diagnosis of mediastinal and/or hilar lymphadenopathy for known or suspected malignancy. Lymph nodes and the surrounding vessels were first visualized with CP-EBUS using the Doppler mode. The dimensions of the lymph nodes were recorded, followed by real-time TBNA under direct EBUS guidance. Final diagnosis was based on cytology, surgical results, and/or clinical follow-up. RESULTS All lymph nodes that were detected on the chest CT scan could be visualized using CP-EBUS. In 70 patients, CP-EBUS-guided TBNA was performed to obtain samples from mediastinal lymph nodes (58 nodes) and hilar lymph nodes (12 nodes). The sensitivity, specificity, and accuracy of CP-EBUS-guided TBNA in distinguishing benign from malignant lymph nodes were 95.7%, 100%, and 97.1%, respectively. The procedure was uneventful, and there were no complications. CONCLUSIONS Real-time CP-EBUS-guided TBNA of mediastinal and hilar lymph nodes is a novel approach that is safe and has a good diagnostic yield. This new ultrasound puncture bronchoscope has an excellent potential for assisting in safe and accurate diagnostic interventional bronchoscopy.
Investigation of physical activity and its correlates in adolescent youth: evaluation of the Youth-Physical Activity Towards Health (Y-PATH) intervention

Objectives: To explore the hypothesised reciprocal relationship between fundamentalmovement skill (FMS) competence and physical activity (PA) behaviour and investigate the role of health-related fitness (HRF) as a mediator of this association. Design: Cross-sectional. Methods: Adolescents aged 12.80 years (SD±.45 years) were recruited from 20 schools (n = 222, 50% male). FMS (TGMD, TGMD-2, Victorian Skills Manual), moderate-to-vigorous physical activity (MVPA) per day (Actigraph accelerometers for a 7-day period), and HRF (3 minute Queens College step test used to calculate a predicted VO2max value) were assessed. Descriptive statistics and frequencies were calculated. Preacher and Hayes (2004), bootstrap method was used to assess the hypothesised reciprocal relationship between FMS and PA and the potential mediating effect of VO2max on the reciprocal relationship between PA and FMS. Mediation was determined using the logic of Baron and Kenny (1986). Results: A reciprocal relationship was found between PA and FMS (τ' = 0.22, p<0.01 in both directions). VO2max mediated 17% and 19% of these relationships, respectively. Conclusion:Analyses suggest a reciprocal relationship between PA and FMS exists in youth. VO2max explained part of this relationship, in both directions, suggesting that increasing adolescent fitness will serve to enhance both PA participation and skill development. The unexplained variance in the reciprocal relationship between PA and FMS must be explored further in an attempt to understand and target this relationship, better.
Space, Time and Consciousness

This paper describes a new theory of consciousness based on previous work by C.D. Broad, H.H. Price, Andrei Linde and others. This hypothesis states that the Universe consists of three fundamental entities — space-time, matter and consciousness, each with their own degrees of freedom. The paper pays particular attention to three areas that impact on this theory: (1) the demonstration by neuroscience and psychophysics that we do not perceive the world as it actually is but as the brain computes it most probably to be; (2) the need to delineate between phenomenal space-time and physical space-time. Recent theories in physics that suggest that the Universe has more than three spatial dimensions are relevant here; (3) the role of consciousness in the block Universe described by Special Relativity. The integration of these topics suggests a new physical theory of the nature of consciousness.
Increased Efficiency Versus Increased Reliability

The vast majority of totally enclosed fan cooled (TEFC) squirrel cage induction motors in the 1-to 20-hp range installed in the petroleum and chemical industries are National Electrical Manufacturers Association (NEMA) "T" frames built prior to 1992, NEMA "T" frames built in accordance with the Energy Policy Act of 1992 (commonly referred to as EPAct motors), and the NEMA Premium motors, introduced after the year 2000, that exceed the EPAct efficiency standards. All three types are available in accordance with the IEEE 841 recommended practice and standards. The most obvious difference in these three generations of motors is their efficiency levels. There has been some concern expressed by the users of these motors that to achieve the premium levels of efficiency it was necessary to compromise other performance characteristics and the motor reliability. This article addresses these claims and shows that they are without basis.
OLFACTORY GROOVE MENINGIOMAS – CLINICAL PRESENTATION , TREATMENT AND OUTCOMES

Olfactory groove meningiomas are benign tumors, which arise in the midline of the anterior cranial fossa, over the cribriform plate and frontosphenoid suture. They represent approximately 10 percent of all intracranial meningiomas, more likely to occur in women in the fifth and sixth decades of life. They often involve the area from the grista galli to the posterior planum sphenoidale, and can be either simetric, bilateral or unilateral based on their midline origin. We report the case of a 45-year-old man who presented with an episode of loss of consciousness, progressive mental disturbances, impairment of visual acuity, anosmia and headache. Gadoliniumenhanced T1-weighted MR images showed a well-defined, hyperintense mass, located in the anterior cranial fossa, measuring 45/50/61 mm, with homogenous enhancement and a broad dural attachment to the cribriform plate, from crista galli to the planum sphenoidale. Preoperative Angiography revealed tumor vascularization from anterior and posterior ethmoidal arteries, branches of ophthalmic artery and branches of external carotid artery. The olfactory groove meningioma was successfully resected using a bifrontal approach with frontal sinuses opened in order to avoid brain retraction. Cranialization with pericranium of frontal sinuses was performed at the end of surgical procedure. Improvement of visual acuity was noted, mental disturbances and seizures remitted, but cerebrospinal leakage occurred, resolved via recranialization of frontal sinuses and lumbar punctions. The last postoperative computer-tomography investigation showed total surgical removal with no recurrence or residual tumor. Total tumor removal must be performed with coagulation of its arachnoid attachments and resection of hyperostotic bone in order to avoid recurrence, but with least brain retraction.
miR-493 mediated DKK1 down-regulation confers proliferation, invasion and chemo-resistance in gastric cancer cells

In the present study, we demonstrated that the levels of DKK1 were decreased in serums and tissues of GC. DKK1 levels inversely correlated with tumor class, TNM stage, distant metastasis and lymph node metastasis of GC. GC patients with low DKK1 levels had a poor overall survival. DKK1 inhibited the proliferation of GC cells in vitro and in vivo. DKK1 also inhibited invasion, but enhanced chemo-sensitivity of GC cells. Mechanically, miR-493 levels increased in GC and directly targeted and down-regulated DKK1 expression. In agreement, miR-493 promoted proliferation of GC cells in vitro and in vivo. MiR-493 also promoted invasion and chemo-resistance of GC cells. However, DKK1 overexpression reversed the effects of miR-493 on proliferation, invasion and chemo-sensitivity. Thus, our results provide new insight for the role of miR-493/DKK1 axis in GC.
Early Life History of Deep-Water Gorgonian Corals May Limit Their Abundance

Deep-water gorgonian corals are long-lived organisms found worldwide off continental margins and seamounts, usually occurring at depths of ∼200–1,000 m. Most corals undergo sexual reproduction by releasing a planktonic larval stage that disperses; however, recruitment rates and the environmental and biological factors influencing recruitment in deep-sea species are poorly known. Here, we present results from a 4-year field experiment conducted in the Gulf of Maine (northwest Atlantic) at depths >650 m that document recruitment for 2 species of deep-water gorgonian corals, Primnoa resedaeformis and Paragorgia arborea. The abundance of P. resedaeformis recruits was high, and influenced by the structural complexity of the recipient habitat, but very few recruits of P. arborea were found. We suggest that divergent reproductive modes (P. resedaeformis as a broadcast spawner and P. arborea as a brooder) may explain this pattern. Despite the high recruitment of P. resedaeformis, severe mortality early on in the benthic stage of this species may limit the abundance of adult colonies. Most recruits of this species (∼80%) were at the primary polyp stage, and less than 1% of recruits were at stage of 4 polyps or more. We propose that biological disturbance, possibly by the presence of suspension-feeding brittle stars, and limited food supply in the deep sea may cause this mortality. Our findings reinforce the vulnerability of these corals to anthropogenic disturbances, such as trawling with mobile gear, and the importance of incorporating knowledge on processes during the early life history stages in conservation decisions.
Logic-Enhanced Type Systems : Programming Language Support for Reasoning about Security and Other Program Properties

Existing compilers that produce certified code (e.g. the Java compiler) focus on relatively simple and informally specified safety properties that are enforced by an elaborate run-time system with a significant performance overhead. Recent research supports the opinion that it is possible to design and implement a general framework for formally reasoning about security and other interesting program properties using low-level languages with strong type systems. In such a language, a certified binary file is simply a program whose type provides a collection of properties that the program satisfies; the type checker can determine statically and with little cost whether a given certified binary is sound and, if it is, the program can be executed with no further performance overhead. In this paper, we exemplify how a formal logic can be embedded in the type system of a programming language. Without plunging into details, we discuss a number of interesting program properties that can be certified and what is to be expected in the foreseeable future.
Powdery Mildew-Induced Mla mRNAs Are Alternatively Spliced and Contain Multiple Upstream Open Reading Frames1

In barley (Hordeum vulgare), theMla13 powdery mildew resistance gene confersRar1-dependent, AvrMla13-specific resistance to Blumeria graminis f. sp.hordei (Bgh). We have identified cDNA and genomic copies of Mla13 and used this coiled-coil nucleotide-binding site leucine-rich repeat protein-encoding gene as a model for the regulation of host resistance to obligate biotrophic fungi in cereals. We demonstrate quantitatively that a rapid increase in the accumulation of Mla transcripts and transcripts of the Mla-signaling genes, Rar1 andSgt1, is triggered between 16 and 20 h post inoculation, the same time frame that haustoria of avirulentBgh make contact with the host cell plasma membrane. An abundance of Mla13 cDNAs revealed five classes of transcript leader regions containing two alternatively spliced introns and up to three upstream open reading frames (uORFs). Alternative splicing of introns in the transcript leader region results in a different number of uORFs and variability in the size of uORF2. These results indicate that regulation of Mlatranscript accumulation is not constitutive and that induction is coordinately controlled by recognition-specific factors. The sudden increase in specific transcript levels could account for the rapid defense response phenotype conferred by Mla6 andMla13.
Employer-sponsored temporary labour migration schemes in Australia, Canada and Sweden: enhancing efficiency, compromising fairness?

ABSTRACT For governments concerned with enhancing labour market efficiency, employer-sponsored temporary labour migration schemes have become increasingly popular. However, the equity implications of these arrangements, which constrain the mobility of migrant workers, have largely been ignored. This paper assesses the factors affecting the vulnerability of employer-sponsored migrant workers and addresses the question of whether these schemes comply with ethical principles relating to fair treatment. It draws upon migration ethics, political economy and socio-legal perspectives to evaluate visa schemes in Australia, Canada and Sweden. The paper argues that there is an ethically justifiable case for selectively restricting certain rights of migrant workers within clearly defined parameters. However, policies facilitating worker mobility, restricting sponsorship to higher-skilled occupations, promoting enforcement and worker representation, and providing accessible opportunities for permanent residency and citizenship help to ensure that employer-sponsored temporary labour migration schemes comply with ethical principles relating to the fair treatment of workers.
The role of schizophrenia susceptibility genes in associative learning

Schizophrenia is highly heritable, indicating that a large proportion of one’s susceptibility to developing the disorder is attributable to genetics. Recent large-scale genomic studies have revealed that genetic variants in patients with schizophrenia affect genes involved in synaptic plasticity processes, which are required for learning and memory, including genes encoding protein complexes associated with the NMDA receptor and the postsynaptic density. Further evidence suggests that associative learning may be particularly affected, although it is unclear which components of this cognitive process are implicated in schizophrenia. The present studies investigated the relationship between particular phases of associative learning, represented by the consolidation, retrieval and extinction of contextual fear memory in rats, with genetic variants, psychoactive drugs and postsynaptic density proteins associated with schizophrenia. I tested associative learning-related gene expression datasets for enrichment in genetic copy number variants from a large cohort of patients with schizophrenia and demonstrated that only genes associated with extinction learning are enriched in patient variants (Chapter 3). I report that fear extinction in rats was impaired by administration of the NMDA antagonist and psychotomimetic, ketamine (Chapter 4). The expression of activity- induced, postsynaptic density products of the Homer1 gene, which has been linked to psychiatric disease, was differentially regulated in specific hippocampal subregions following extinction learning (Chapter 5), and the effect of a partial knockdown of these genes during different phases of associative learning was investigated (Chapter 6). These results build on clinical studies linking abnormalities in associative and, specifically, extinction learning with schizophrenia and support the notion that genetic variants associated with the disorder impact particular cognitive domains. My findings are consistent with the theory that altered inhibitory-type learning processes contribute to the manifestation of schizophrenia.
Adaptive Individual Differences

Individuals differ in innumerable ways, some adaptive, some maladaptive, and some neutral. Personality theories, we argue, can profit from distinguishing among these importantly different types of individual variation. This article outlines a taxonomy of origins of individual differences—environ- mental sources of adaptive differences(e.g., early environmental calibration), heritable sources of adaptive differences (e.g., adaptive self-assessment of heritable qualities), nonadaptive sources of individual differences(e.g., inciden- tal by-products of adaptive variation), and maladaptive sources of individual differences (e.g., epigenetic trauma). The second section outlines empirical procedures for confirming or falsifying the differing conceptions of individual differences, with a special focus on empirically distinguishing adaptive individ- ual differences from those that are maladaptive or nonadaptive. The final section highlights the importance of individual differences for solving social adaptive problems. Scientists since Darwin (1859) have known that members of single species show marked differences from one another. A coherent theoreti- cal understanding of the origins and possible functions of individual
Ad hoc subgroup proofs for RFID

In many RFID applications it is necessary to be able to identify the presence of (all) the tags of a predefined group, e.g., to establish that all components of a kit are present. If the interrogation is offline, by RFID readers that do not share any secret keys with the tags, then a record of simultaneous presence, or agrouping proof , has to be generated by the tags themselves. This type of proof is typically obtained by assigning to each tag in the group a unique group identifier. In certain situations, however, the entire group may not be present, and it may be sufficient that a (an ad hoc) subgroup proof is generated. In this paper we consider ad hoc subgroup proofs . We first describe a generic ad hoc subgroup proof by extending a previously proposed grouping proof to an ad hoc setting. We then propose a novel ad hoc subgroup proof for RFID that supports privacy (unlinkability).
Vers une approche Bio-inspirée pour l'orchestration pédagogique des activités mobiles d'apprentissage

Cet article presente une nouvelle approche pour recommander des parcours d'apprentissage adaptes au contexte des apprenants mobiles. Pour cela, nous proposons un systeme de filtrage collaboratif des points d'interet qui permet de guider l'apprenant dans le cadre d'une sortie pedagogique. Ce systeme de recommandation permet ainsi l’orchestration automatique des activites mobiles d’apprentissage en fonction de la localisation geographique des apprenants et de leurs historiques.
A Comparative Evaluation of Amitriptyline and Duloxetine in Painful Diabetic Neuropathy

OBJECTIVE To compare the efficacy and safety of duloxetine and amitriptyline in painful diabetic neuropathy (PDN). RESEARCH DESIGN AND METHODS In this randomized, double-blind, cross-over, active-control trial, 58 patients received amitriptyline and duloxetine orally once daily at bedtime, each for 6 weeks with optional dose uptitration fortnightly. Single-blinded placebo washout was given for 2 weeks between the two treatments and a single-blinded placebo run-out phase of 4 weeks was given at the end of the treatment period. Pain relief was measured by the patient’s global assessment of efficacy, using a visual analog scale (0–100) as a primary end point, and overall improvement and adverse events were assessed as secondary outcome measures. Median pain score reductions of >50%, 25–50%, and <25% were considered good, moderate, and mild responses, respectively. RESULTS There was a significant improvement in pain with both treatments compared with their baseline values (P < 0.001 for both). Good, moderate, and mild pain relief was achieved in 55, 24, and 15% of patients, respectively, on amitriptyline and 59, 21, and 9% of patients, respectively, on duloxetine. There were no significant differences in various other outcome measures between the groups. Of the reported adverse events, dry mouth was significantly more common with amitriptyline than duloxetine (55 vs. 24%; P < 0.01). Although, numerically, more patients preferred duloxetine, overall this was not statistically significant (48 vs. 36%; P = 0.18). CONCLUSIONS Both duloxetine and amitriptyline demonstrated similar efficacy in PDN. A large, multicentric clinical trial in other populations could possibly demonstrate the superiority of either drug.
Computing Location from Ambient Radio Signals

We present a method for computing the location of a device down to a radius of several miles within a greater metropolitan area by analyzing the signal strengths observed from commercial FM radio stations. The use of ambient commercial radio signals allows for wide coverage, both indoor and outdoor reception, client-side computing for privacy, and the feasibility of employing inexpensive, low-power measurement hardware. Our technique is based on a model for computing the likelihood of locations using both received signal strengths and information from a simulated signal strength map. Using simulated signal strengths relieves the burden of manually measuring signal strength as a function of location. We account for the inevitable measurement variations among devices by comparing rankings of radio stations by signal strength. Our experiments show we can measure location down to a median error of about 8 kilometers (5 miles) in the greater Seattle area by listening to seven different radio stations.