Miracle-dz/UniFAR-FTUs huggingface dataset:
Towards reflexive land and water management in Iran: linking technology, governance and culture.

Key words: Qanat, land and water, sustainability, Industrial and reflexive modernity This PhD thesis is concerned with the causes and consequences of the environmental crisis and explores possible trajectories towards sustainable land and water management in Iran and other countries of the Middle East and North Africa (MENA). The basic assumption underlying the conceptual framework of this thesis is that soil and water technologies, social institutions and environmental mentalities are strongly interconnected; they co-evolve, shaping and reshaping one another in the process. The main research question concerns the changes within this network of technologies, institutions and mentalities that are required for a successful transition from industrial modernity to what sociologists like Ulrich Beck, Anthony Giddens and Scott Lash have called ‘reflexive’ modernity. In order to examine the possibilities and problems of a reflexive turn in land and water management in Iran and other MENA-countries, large-scale empirical studies were conducted among farmers and village informants, soil and water experts, and policymakers.
Fur mites of the family Listrophoridae (Acariformes: Sarcoptoidea) associated with South American sigmodontine rodents (Cricetidae: Sigmodontinae)

Six species of 3 genera belonging to the fur mite family Listrophoridae were recorded on skins of South American rodents of the cricetid subfamily Sigmodontinae housed in the Bavarian State Collection of Zoology (Munich, Germany). Among them, Amlistrophorus geoxus sp. nov. from Geoxus valdivianus from Chile is described as a new for science, and males of Prolistrophorus amazonicus amazonicus Fain, 1971 are recorded for the first time. The full generic status for the subgenus Amlistrophorus of the genus Prolistrophorus proposed by Fain et al. (1996) is not supported, and Prolistrophorus musculinus Fain, 1973 stat. nov. (formerly a subspecies of P. amazonicus) from Mus musculus (Rodentia: Muridae) from Suriname is raised to species status. New hosts are recorded for the following species: Prolistrophorus argentinus (Hirst, 1921) from Holochilus brasiliensis and H. chacarius from Argentina, P. amazonicus from Calomys callosus from Argentina and Bolivia, C. laucha and C. musculinus from Argentina, P. akodon Fain and Lukoschus, 1982 from Akodon montensis from Argentina, P. nectomys Fain, 1971 from Nectomys palmipes from Peru and Melanomys caliginosus from Panama, and Sclerolistrophorus oxymycteris Fain, 1976 from Oryzomys laticeps from Brazil.
An uncoupling agent containing strontium prevents bone loss by depressing bone resorption and maintaining bone formation in estrogen‐deficient rats

Trabecular bone loss in estrogen deficiency is associated with enhanced bone resorption with a smaller increase in bone formation. We previously reported that low doses of strontium can increase trabecular bone volume in rodents by affecting bone resorption and formation. In this study we determined the effect of a new divalent strontium salt (S12911) on bone loss induced by E2 deficiency. Sprague‐Dawley female rats (230 g, n = 15–25 per group) were sham operated or ovariectomized (OVX) and treated with 17β‐estradiol (E2, 10 μg/kg/day, sc) or S12911 by gavage at the dose of 77, 154, or 308 mg/kg/day or the vehicle. Treatment for 60 days with S12911 resulted in a dose‐dependent increase in plasma, urine, and bone strontium concentrations without any deleterious effect on total or skeletal growth. OVX rats were osteopenic compared to sham rats as shown by decreased femoral dry bone weight and mineral content measured on bone ash and by DXA. Treatment of OVX rats with S12911 prevented bone loss as bone ash and bone mineral content were restored to the values in sham rats. Trabecular bone volume measured by histomorphometry on the tibial metaphysis was decreased by 46% in OVX rats and was corrected by E2. Treatment of OVX rats with S12911 increased the trabecular bone volume by 30–36%. Histomorphometric indices of bone resorption (osteoclast surface and number) were increased in OVX rats and were reduced by S12911 to the levels in sham rats. In contrast to this inhibitory effect on bone resorption, the osteoid surface, osteoblast surface, mineral apposition rate, and bone formation rate were as high in OVX rats treated with S12911 as in untreated OVX rats. In addition, plasma osteocalcin (OC) and alkaline phosphatase (ALP) levels remained elevated or were further increased in OVX rats treated with S12911. In contrast, treatment with E2 reduced both bone resorption and formation and plasma ALP and OC to the levels in sham rats. The data indicate that the divalent strontium salt S12911 is acting as an uncoupling agent that can prevent the femoral osteopenia and partially prevent the trabecular bone loss in E2‐deficient rats by inhibiting bone resorption without reducing bone formation.
Are the actively respiring cells (CTC+) those responsible for bacterial production in aquatic environments?

The 5-cyano-2,3-ditolyl tetrazolium chloride (CTC) staining method is commonly and increasingly used to detect and to enumerate actively respiring cells (CTC+ cells) in aquatic systems. However, this method remains controversial since some authors promote this technique while others pointed out several drawbacks of the method. Using flow cytometry (FCM), we showed that CTC staining kinetics vary greatly from one sample to another. Therefore, there is no universal staining protocol that can be applied to aquatic bacterial communities. Furthermore, using (3)H-leucine incorporation, it was shown that the CTC dye has a rapid toxic effect on bacterial cells by inhibiting protein synthesis, a key physiological function. The coupling of radioactive labelling with cell sorting by FCM suggested that CTC+ cells contribute to less than 60% of the whole bacterial activity determined at the community level. From these results, it is clearly demonstrated that the CTC method is not valid to detect active bacteria, i.e. cells responsible for bacterial production.
Structural and Functional Insights into the Pilotin-Secretin Complex of the Type II Secretion System

Gram-negative bacteria secrete virulence factors and assemble fibre structures on their cell surface using specialized secretion systems. Three of these, T2SS, T3SS and T4PS, are characterized by large outer membrane channels formed by proteins called secretins. Usually, a cognate lipoprotein pilot is essential for the assembly of the secretin in the outer membrane. The structures of the pilotins of the T3SS and T4PS have been described. However in the T2SS, the molecular mechanism of this process is poorly understood and its structural basis is unknown. Here we report the crystal structure of the pilotin of the T2SS that comprises an arrangement of four α-helices profoundly different from previously solved pilotins from the T3SS and T4P and known four α-helix bundles. The architecture can be described as the insertion of one α-helical hairpin into a second open α-helical hairpin with bent final helix. NMR, CD and fluorescence spectroscopy show that the pilotin binds tightly to 18 residues close to the C-terminus of the secretin. These residues, unstructured before binding to the pilotin, become helical on binding. Data collected from crystals of the complex suggests how the secretin peptide binds to the pilotin and further experiments confirm the importance of these C-terminal residues in vivo.
Exposure to Secondhand Smoke and Risk of Tuberculosis: Prospective Cohort Study

Background Prospective evidence on the association between secondhand-smoke exposure and tuberculosis is limited. Methods We included 23,827 never smokers from two rounds (2001 and 2005) of Taiwan National Health Interview Survey. Information on exposure to secondhand smoke at home as well as other sociodemographic and behavioral factors was collected through in-person interview. The participants were prospectively followed for incidence of tuberculosis through cross-matching the survey database to the national tuberculosis registry of Taiwan. Results A total of 85 cases of active tuberculosis were identified after a median follow-up of 7.0 years. The prevalence of exposure to secondhand smoke at home was 41.8% in the study population. In the multivariable Cox proportional hazards analysis, secondhand smoke was not associated with active tuberculosis (adjusted hazard ratio [HR], 1.03; 95% CI, 0.64 to 1.64). In the subgroup analysis, the association between secondhand smoke and tuberculosis decreased with increasing age; the adjusted HR for those <18, > = 18 and <40, > = 40 and <60, and > = 60 years old was 8.48 (0.77 to 93.56), 2.29 (0.75 to 7.01), 1.33 (0.58 to 3.01), and 0.66 (0.35 to 1.23) respectively. Results from extensive sensitivity analyses suggested that potential misclassification of secondhand-smoke exposure would not substantially affect the observed associations. Conclusions The results from this prospective cohort study did not support an overall association between secondhand smoke and tuberculosis. However, the finding that adolescents might be particularly susceptible to secondhand smoke's effect warrants further investigation.
A Decision Heuristic for Party Identification: New British and German Data and a New Understanding for a Classic Concept

The concept party identification lies at the heart of much research on political preferences and behavior in established democracies. Drawing on data obtained from the British Household Panel Survey (1991-99) and the German Socio-Economic Panel Survey (1984-1998), we offer a fresh approach to the concept. Party identification is a stance that people take towards the political parties. They apply a consistent rule -a decision heuristic -persistently returning to the same preference year after year or behaving haphazardly, moving with no clear pattern among the choices. Most take a definitively negative stance towards one of the parties and a positive stance towards the other major party. Of these, about half display behavior that reflects a psychological commitment and about half are as likely as not to pick that party when asked. For most people, party identification is neither a loyalty, as conceived by traditional understanding associated with the Michigan -nor a calculated choice -as offered by rational choice theory -but a way to situate oneself persistently in relation to the relatively distant objects of politics.
Procrastination and Obedience

In this lecture I shall focus on situations involving repeated decisions with time inconsistent behavior. Although each choice may be close to maximizing and therefore result in only small losses, the cumulative effect of a series of repeated errors may be quite large. Thus, in my examples, decision makers are quite close to the intelligent, well-informed individuals usually assumed in economic analysis, but cumulatively they make seriously wrong decisions that do not occur in standard textbook economics. This lecture discusses and illustrates several "pathological" modes of individual and group behavior: procrastination in decision making, undue obedience to authority, membership of seemingly normal individuals in deviant cult groups, and escalation of commitment to courses of action that are clearly unwise. In each case, individuals choose a series of current actions without fully appreciating how those actions will affect future perceptions and behavior. The standard assumption of rational, forwardlooking, utility maximizing is violated. The nonindependence of errors in decision making in the series of decisions can be explained with the concept from cognitive psychology of undue salience or vividness. For example, present benefits and costs may have undue salience relative to future costs
Gut to Brain Dysbiosis: Mechanisms Linking Western Diet Consumption, the Microbiome, and Cognitive Impairment

Consumption of a Western Diet (WD) that is high in saturated fat and added sugars negatively impacts cognitive function, particularly mnemonic processes that rely on the integrity of the hippocampus. Emerging evidence suggests that the gut microbiome influences cognitive function via the gut-brain axis, and that WD factors significantly alter the proportions of commensal bacteria in the gastrointestinal tract. Here we review mechanisms through which consuming a WD negatively impacts neurocognitive function, with a particular focus on recent evidence linking the gut microbiome with dietary- and metabolic-associated hippocampal impairment. We highlight evidence linking gut bacteria to altered intestinal permeability and blood brain barrier integrity, thus making the brain more vulnerable to the influx of deleterious substances from the circulation. WD consumption also increases production of endotoxin by commensal bacteria, which may promote neuroinflammation and cognitive dysfunction. Recent findings also show that diet-induced alterations in gut microbiota impair peripheral insulin sensitivity, which is associated with hippocampal neuronal derrangements and associated mnemonic deficits. In some cases treatment with specific probiotics or prebiotics can prevent or reverse some of the deleterious impact of WD consumption on neuropsychological outcomes, indicating that targeting the microbiome may be a successful strategy for combating dietary- and metabolic-associated cognitive impairment.
Detecting and quantifying different types of self-admitted technical Debt

Technical Debt is a term that has been used to express non-optimal solutions during the development of software projects. These non optimal solutions are often shortcuts that allow the project to move faster in the short term, at the cost of increased maintenance in the future. To help alleviate the impact of technical debt, a number of studies focused on the detection of technical debt. More recently, our work shown that one possible source to detect technical debt is using source code comments, also referred to as self-admitted technical debt. However, what types of technical debt can be detected using source code comments remains as an open question. Therefore, in this paper we examine code comments to determine the different types of technical debt. First, we propose four simple filtering heuristics to eliminate comments that are not likely to contain technical debt. Second, we read through more than 33K comments, and we find that self-admitted technical debt can be classified into five main types - design debt, defect debt, documentation debt, requirement debt and test debt. The most common type of self-admitted technical debt is design debt, making up between 42% to 84% of the classified comments. Lastly, we make the classified dataset of more than 33K comments publicly available for the community as a way to encourage future research and the evolution of the technical debt landscape.
Retinal Reflectivity Measurement for Cone Impairment Estimation and Visual Assessment After Diabetic Macular Edema Resolution (RECOVER-DME).

Purpose Photoreceptor loss has been suspected of being involved in incomplete visual recovery after diabetic macular edema (DME) resolution. Recent studies have shown that cone density in the perifoveal area could be estimated by in vivo measurements of the outer retinal reflectivity on optical coherence tomography (OCT). The main objective of this study was to assess the photoreceptor layer reflectivity after DME resolution and to determine its relationship with final visual acuity (VA). Methods In this cross-sectional case-control study, 77 eyes of 58 patients were divided into three groups: a first group (n = 34) encompassed eyes with resolved DME (R-DME), a second group (n = 24) corresponded to diabetic eyes without DME (no-DME), and a third group (n = 19) comprised a control group of nondiabetic healthy eyes. Outer retinal reflectivity was measured on volumetric spectral-domain (SD)-OCT scans acquired 3 months after DME resolution, from the photoreceptor ellipsoid zone (EZ) and the retinal pigment epithelium (RPE). Results The mean DME duration was 26.5 ± 13.4 months in the R-DME group. EZ reflectivity was 19.8% lower (P < 0.0001) in this group compared to diabetic eyes without DME and 26.5% lower (P < 0.0001) than in nondiabetic control eyes. Reflectivity was 7.8% lower in the no-DME group compared to controls (P < 0.0001). RPE reflectivity was comparable among the three groups (P > 0.05). VA was significantly correlated with EZ reflectivity in diabetic patients (r2 = 0.57; P < 0.0001). Reflectivity tended to decrease with prolonged DME duration without reaching statistical significance (P = 0.10). Conclusions DME significantly impacts the photoreceptor layer. This impairment can be estimated by measuring outer retinal reflectivity on OCT images after edema resorption. We also provide evidence that in diabetic eyes without a history of DME, there is early photoreceptor loss, or at least outer segment (OS) disorganization, in addition to the inner retinal degeneration reported previously. This suggests the neurodegenerative process in diabetes. This quantitative approach may help monitor neuroprotective strategies to rescue photoreceptor cells in diabetic eyes.
A novel approach for achieving bulk silicon MEMS on CMOS substrate by Au-Au bonding

This paper presents a new approach for achieving single-crystal silicon MEMS on CMOS substrate. Through this technology, High-performance bulk-Si MEMS sensors are merged with the integrated circuit (IC) technology. Also, substrate isolation and electrical interconnection between the CMOS circuits and MEMS sensors are achieved perfectly. In applications, the pressure sensor and electrothermal actuator have been realized and monolithic integrated using this approach. The measurement results show that sensitivities of the pressure sensor and the electrothermal actuator are 0.29fF/hPa, and 19. 6µm/V, respectively. The measurement ranges are 450–1010hPa, and 1.8–2.7V, respectively.
Ant colony inspired self-optimized routing protocol based on cross layer architecture for wireless sensor networks

Nowadays, wireless sensor networks (WSNs) are becoming increasingly beneficial, worthwhile and a challenging research area. The advancements in WSN enable a wide range of environmental monitoring and object tracking applications. Moreover, multihop (node by node) routing in WSN is affected by new devices constantly entering or leaving the network. Therefore, nature inspired self-maintained protocols are required to tackle the problems arising in WSN. We proposed ant colony stimulated routing, which shows an outstanding performance for WSNs. In this manuscript, a cross layer design based selfoptimized (ACO) routing protocol for WSN and the results are presented. Link quality, energy level and velocity parameters are used to discover an optimal route. The signal strength, remaining power and timestamp metrics are trade in from physical layer to network layer. The emitted decision through the WSN discovery will establish the optimal route from source to destination. The adopted cross layer architecture helps ACO in improving the overall data delivery ratio; especially in the case of real time traffic.
Adventitial Mast Cells Contribute to Pathogenesis in the Progression of Abdominal Aortic Aneurysm

Abdominal aortic aneurysm (AAA) is histologically characterized by medial degeneration and various degrees of chronic adventitial inflammation, although the mechanisms for progression of aneurysm are poorly understood. In the present study, we carried out histological study of AAA tissues of patients, and interventional animal and cell culture experiments to investigate a role of mast cells in the pathogenesis of AAA. The number of mast cells was found to increase in the outer media or adventitia of human AAA, showing a positive correlation between the cell number and the AAA diameter. Aneurysmal dilatation of the aorta was seen in the control (+/+) rats following periaortic application of calcium chloride (CaCl2) treatment but not in the mast cell–deficient mutant Ws/Ws rats. The AAA formation was accompanied by accumulation of mast cells, T lymphocytes and by activated matrix metalloproteinase 9, reduced elastin levels and augmented angiogenesis in the aortic tissue, but these changes were much less in the Ws/Ws rats than in the controls. Similarly, mast cells were accumulated and activated at the adventitia of aneurysmal aorta in the apolipoprotein E–deficient mice. The pharmacological intervention with the tranilast, an inhibitor of mast cell degranulation, attenuated AAA development in these rodent models. In the cell culture experiment, a mast cell directly augmented matrix metalloproteinase 9 activity produced by the monocyte/macrophage. Collectively, these data suggest that adventitial mast cells play a critical role in the progression of AAA.
PLU-E: a proposed framework for planning and conducting evaluation studies with children

While many models exist to support the design process of a software development project, the evaluation process is far less well defined and this lack of definition often leads to poorly designed evaluations, or the use of the wrong evaluation method. Evaluations of products for children can be especially complex as they need to consider the different requirements and aims that such a product may have, and often use new or developing evaluation methods. This paper takes the view that evaluations should be planned from the start of a project in order to yield the best results, and proposes a framework to facilitate this. This framework is particularly intended to support the varied and often conflicting requirements of a product designed for children, as defined by the PLU model, but could be adapted for other user groups.
Automatic Extraction of Subcorpora based on Subcategorization Frames from a Part-ofSpeech Tagged Corpus

This paper presents a method for extracting subcorpora documenting different subcategorization frames for verbs, nouns, and adjectives in the 100 mio. word British National Corpus. The extraction tool consists of a set of batch files for use with the Corpus Query Processor (CQP), which is part of the IMS corpus workbench (cf. Christ 1994a, b). A macroprocessor has been developed that allows the user to specify in a simple input file which subcorpora are to be created for a given lemma.The resulting subcorpora can be used (1) to provide evidence for the subcategorization properties of a given lemma, and to facilitate the selection of corpus lines for lexicographic research, and (2) to determine the frequencies of different syntactic contexts of each lemma.
Hierarchical Maximum Pattern Matching with Rule Induction Approach for Sentence Parsing

Chinese parsing has been a highly active research area in recent years. This paper describes a hierarchical maximum pattern matching to integrate rule induction approach for sentence parsing on traditional Chinese parsing task. We have analyzed and extracted statistical POS (part-of-speech) tagging information from training corpus, then used the related information for labeling unknown words in test data. Finally, the rule induction regulation was applied to extract of the structure of short-term syntactic and then performed maximum pattern matching for longterm syntactic structure. On Sentence Parsing task, our system performs at 44% precision, 53% recall, and F1 is 48% in the formal testing evaluation. The proposed method can achieve the significant performance in traditional Chinese sentence parsing.