Miracle-dz/UniFAR-FTUs huggingface dataset:
Factorial analysis of psychological and technical-tactic fitness of tennis players at stage of specialized basic training

Цель : определить структуру психологической и технико-тактической подготовленности теннисистов методом главных компонент. Материал : в исследованиях приняли участие 24 теннисиста 14-15 лет. Для определения личностных психологических свойств юных теннисистов использовались методики: Дембо-Рубинштейна (исследование самооценки), Бурдона-Анфимова (внимание), тест Г. Айзенка (тип темперамента), методики Т. Элерса (мотивация), тест Спилбергега-Ханина (уровень тревожности). Результаты : Установлена структура психологической и технико-тактической подготовленности теннисистов, которые пребывают на этапе специализированной базовой подготовки. Для психологической подготовленности было определено пять факторов, для технико-тактической - три фактора. Высокий уровень межфакторных взаимосвязей наблюдался лишь для структуры технико-тактической подготовленности. Значимых связей между пятью факторами психологической подготовленности выявлено не было. Выводы : установленные особенности факторной структуры подготовленности теннисистов могут быть использованы во время планирования программ психологической подготовки и учебно-тренировочного процесса юных игроков.
Evaluation of Left Ventricular Diastolic Dysfunction in Asymptomatic Normotensive Patients with Type-2 Diabetes Mellitus

1 Assistant Professor, Dept of Medicine, P.S. Medical College, Karamsad, Anand-388325, Gujarat, India 2 Programme Officer, GorakhpurJhpiego Corporation Uttar Pradesh, India 3 Deputy Chief Medical officer, Department of Medicine, Mumbai Port Trust Hospital, Wadala (E), Mumbai Corresponding Author Dr Kalyan Mansukhbhai Shekhda 218, New Shakti Vijay Soc; Opp. Surat Super Store, Varachha Road, Surat – 395006 Email: kalokly@gmail.com, Number: +919769700302 ABSTRACT Introduction: Diabetes mellitus (DM) is known to affect cardiovascular system adversely. Various studies reported left ventricular diastolic dysfunction (LVDD) as an early sign of cardiac involvement in asymptomatic patients with type-2 DM, diagnosed using Color Doppler echocardiography. With this background, the study was conducted with an aim to study the prevalence of LVDD in normotensive asymptomatic type-2 DM patients and association with various risk factors. Methodology: The cross-sectional study was carried out among the type 2 DM patients who visited our hospital for regular follow-up. 100 patients of type 2 DM were enrolled and patients without the history of hypertension, Heart diseases, renal dysfunction were recruited on a convenient basis. Demographic data such as age, sex, history, duration, treatment of DM, Investigations like Fasting and Postprandial blood sugar levels, Serum Creatinine, Fasting lipid profile, HbA1c, and also ECG, 2D echocardiography, and Treadmill test were carried out. Data were entered in MS Excel spread sheet and analysed with the help of SPSS software packages and Open Epi. Chi-square test was used for the comparison of qualitative data. Results: LVDD was present in 64 (64%) among 100 patients. A strong association of LVDD with Duration of Diabetes and HbA1c (p<0.001) was observed but there was no correlation with age, sex, Type of Treatment, total cholesterol, triglycerides, high-density lipoprotein. Conclusion: Duration of diabetes and the level of HbA1c were found to have a strong association with LVDD. It is recommended that all patients with long term and uncontrolled type 2 DM should be screened for LVDD.
Ligand-induced folding of the thiM TPP riboswitch investigated by a structure-based fluorescence spectroscopic approach

Riboswitches are genetic control elements within non-coding regions of mRNA. They consist of a metabolite-sensitive aptamer and an adjoining expression platform. Here, we describe ligand-induced folding of a thiamine pyrophosphate (TPP) responsive riboswitch from Escherichia coli thiM mRNA, using chemically labeled variants. Referring to a recent structure determination of the TPP/aptamer complex, each variant was synthesized with a single 2-aminopurine (AP) nucleobase replacement that was selected to monitor formation of tertiary interactions of a particular region during ligand binding in real time by fluorescence experiments. We have determined the rate constants for conformational adjustment of the individual AP sensors. From the 7-fold differentiation of these constants, it can be deduced that tertiary contacts between the two parallel helical domains (P2/J3-2/P3/L3 and P4/P5/L5) that grip the ligand's ends in two separate pockets, form significantly faster than the function-critical three-way junction with stem P1 fully developed. Based on these data, we characterize the process of ligand binding by an induced fit of the RNA and propose a folding model of the TPP riboswitch aptamer. For the full-length riboswitch domain and for shorter constructs that represent transcriptional intermediates, we have additionally evaluated ligand-induced folding via AP-modified variants and provide insights into the sequential folding pathway that involves a finely balanced equilibrium of secondary structures.
Effectiveness of forward collision warnings for different driver attention states

In recent years various collision warning systems for rear-end crash situations have been introduced into the market. Their goal is to reduce the number of fatalities and to mitigate collision consequences. The challenge in the design for such functions is to achieve a high effectiveness for both attentive and inattentive drivers. A possible approach could be an adaptation of the human-machine interface (HMI) to driver attentiveness levels. This paper presents a preliminary study of different visual-acoustical HMI concepts performed in a driving simulator. The participants completed two drives with each warning signal. In the first drive they were distracted by a secondary task and in the second one they were in an attentive state. The statistical analysis of the inattentive drivers' data showed a significant reaction time reduction by employing an acoustical speech warning. A visual alert for inattentive subjects did not result in an additional reduction. Only a simple and intuitive visual display showed a significant reduction of response time for attentive participants. The results of this study show that for varying driver attentiveness levels a warning intensity adaptation is needed in order to increase the benefit and acceptance of the collision warning.
Multifunctional materials for bone cancer treatment

The purpose of this review is to present the most recent findings in bone tissue engineering. Special attention is given to multifunctional materials based on collagen and collagen–hydroxyapatite composites used for skin and bone cancer treatments. The multi-functionality of these materials was obtained by adding to the base regenerative grafts proper components, such as ferrites (magnetite being the most important representative), cytostatics (cisplatin, carboplatin, vincristine, methotrexate, paclitaxel, doxorubicin), silver nanoparticles, antibiotics (anthracyclines, geldanamycin), and/or analgesics (ibuprofen, fentanyl). The suitability of complex systems for the intended applications was systematically analyzed. The developmental possibilities of multifunctional materials with regenerative and curative roles (antitumoral as well as pain management) in the field of skin and bone cancer treatment are discussed. It is worth mentioning that better materials are likely to be developed by combining conventional and unconventional experimental strategies.
Performance evaluation of a controlled drift detector for diffraction enhanced breast imaging

Diffraction enhanced breast imaging could potentially give a significant increase in contrast and sensitivity to tissue type with respect to conventional transmission X-ray mammography. A device that looks extremely promising for this application area is the controlled drift detector as it has the basic features of a charge-coupled device in terms of small pixel size but it is superior to the charge-coupled device in certain key areas as it can operate (a) in photon counting mode measuring the energy with spectroscopic resolution, (b) at very high frame rates (up to 100 kHz) and it can potentially be constructed to a large area linear device. The first results of a thorough performance evaluation of the controlled drift detector in its application to diffraction enhanced breast imaging are presented and discussed
Assessing the potential of Channel NewsAsia as the next ‘Al Jazeera’: A comparative discourse analysis of Channel NewsAsia and the BBC

In the last decade, Western news organizations such as CNN and the BBC have been increasingly upstaged by satellite news services from the global South. The Qatari news network, Al Jazeera, has emerged as a prime example of a global media contra-flow that has been able to give its region a voice in the international news arena. At a time when developments like the global economic crisis have called for greater checks and balances on Western governments and corporations, this paper takes a critical look at an increasingly prominent news player in the fast-growing developing region of East Asia, Channel NewsAsia, to ascertain if it is likely to rise up the ranks to the level of Al Jazeera. A critical discourse analysis comparing the coverage of Channel NewsAsia and the BBC’s most salient stories, however, shows that the Singapore-based station falls short in its claim to ‘provide Asian perspectives’ because it is constrained by political-economic factors to operate within an authoritarian developmental news model.
Quality assessment of clusters of electrical disturbances: A case study

Electrical disturbances can have an adverse affect on people, businesses and other systems, and increased understanding of such events has huge potential benefits. Clustering or unsupervised learning is a technique of computational intelligence that can be used to identify natural clusters or groups of disturbances. The understanding of disturbances is important for planning and maintenance, and may lead to fresh insights which prove useful in upgrade of infrastructure. Ideally this should be a fully automated process, so that no bias is introduced by the practitioner. The complete process involves several steps including data cleaning, transformation, feature selection, clustering, evaluation of clusters, cluster description and cluster interpretation. We designate this process as the Clustering Knowledge Chain, beginning with raw data and ending with new knowledge. This case study examines each of these steps, showing how they might be applied in a situation involving real-world data, and illustrates some of the difficulties that a practitioner with domain knowledge may encounter. Results from this case study reveal new knowledge about electrical disturbances, but also show that selection of parameters using a quantitative measure of clustering quality is not enough, by itself, to guarantee clusters that can inform the practitioner.
Component-Based Composition of Wide-Area Workflows

The evolution of workflow models has been characterized by profound flux ever since the formative days of flow charts. Despite, or because of, a proliferation of workflow-oriented standards, none can honestly claim to be ubiquitous. In a widely distributed grid, gaps will inevitably exist in the model of workflows deployed therein. Thus, there is a need to present a consistent view of disparate processes to high-level roles such as analysts. To that end, we propose virtualizing the workflow layer to reconcile such gaps, both in the modeling and the execution sense. Given a wide area network of workflow providers, we overlay it with one based on WS-BPEL, our reference model. For every provider, we build virtualization-enabling silos, realized as components driven by a SCA container. Further, we describe design patterns to facilitate bindings to other models at various levels. Finally, we take reality checks by identifying those patterns in such standards as BPMN, XPDL, WWF and ebBP.
Automatically extracting mock object behavior from Design by Contract#8482; specification for test data generation

Test data generation is an important task in the process of automated unit test generation. Random and heuristic approaches are well known for test input data generation. Unfortunately, in the presence of complex pre-conditions especially in the case of non-primitive data types those approaches often fail. A promising technique for generating an object that exactly satisfies a given pre-condition is mocking, i.e., replacing the concrete implementation with an implementation only considering the necessary behavior for a specific test case. In this paper we follow this technique and present an approach for automatically deriving the behavior of mock objects from given Design by Contract#8482; specifications. The generated mock objects behave according to the Design by Contract#8482; specification of the original class. Furthermore, we make sure that the observed behavior of the mock object satisfies the pre-condition of the method under test. We evaluate the approach using the Java implementations of 20 common Design Patterns and a stack based calculator. Our approach clearly outperforms pure random data generation in terms of line coverage.
Structure and function of the small terminase component of the DNA packaging machine in T4-like bacteriophages

Tailed DNA bacteriophages assemble empty procapsids that are subsequently filled with the viral genome by means of a DNA packaging machine situated at a special fivefold vertex. The packaging machine consists of a “small terminase” and a “large terminase” component. One of the functions of the small terminase is to initiate packaging of the viral genome, whereas the large terminase is responsible for the ATP-powered translocation of DNA. The small terminase subunit has three domains, an N-terminal DNA-binding domain, a central oligomerization domain, and a C-terminal domain for interacting with the large terminase. Here we report structures of the central domain in two different oligomerization states for a small terminase from the T4 family of phages. In addition, we report biochemical studies that establish the function for each of the small terminase domains. On the basis of the structural and biochemical information, we propose a model for DNA packaging initiation.
New interpretations of the skull of a primitive bony fish Erpetoichthys calabaricus (Actinopterygii: Cladistia)

Polypterid fishes are considered the basalmost group of extant actinopterygians and may be a direct link to understanding the systematics and evolution of the first bony fishes. Several investigations have been conducted on one member genus, Polypterus; however, since the first specimens of its sister taxon Erpetoichthys calabaricus were described, remarkably little work has been done on the species. We review terminology critical to understanding cranial morphology in polypterids and present a new description of the skull of E. calabaricus as observed through classical methods of skeletal preparation, X‐radiographic microfocus computed tomography, and 3D‐digital reconstruction. Differences among E. calabaricus and at least three species of Polypterus (P. bichir, P. senegalus, and P. endlicheri), besides the gross variation in size, include an overall elongation of the skull roof observable in most elements of E. calabaricus with a shortening of most associated processes. In addition, several elements present in species of Polypterus are absent in E. calabaricus. As a result, Polypterus should not be used as a proxy for the family Polypteridae to the exclusion of E. calabaricus in phylogenetic studies, which examine early actinopterygians. Each should be treated separately, to resolve inter‐ and intrarelationships of Polypteridae. J. Morphol. , 2007. © 2007 Wiley‐Liss, Inc.
Differences in light sleep and deep sleep measured with IST Vivago WristCare

Activity monitoring is a widespread alternative to polysomnography (PSG) in studying sleep/wake patterns because it enables inexpensive long-term monitoring and does not require laboratory conditions for recording. IST Vivago® WristCare is a wrist worn activity monitoring device, which has been found to produce similar results to traditional actigraphs in sleep/wake detection. The movement sensor of Vivago® is more sensitive to low intensity movements than that of traditional actigraphs. We compared activity measured with IST Vivago® during deep sleep, light sleep and awake. The results showed that average (p<0.001) and standard deviation (p<0.00001) of activity are significantly lower in deep sleep than in light sleep. However, minute-by-minute classification of sleep level was not successful. In conclusion, Vivago® activity gives indication of the overall sleep quality, but does not allow sleep stage classification.
Fear Responses to Threat Appeals: Functional Form, Methodological Considerations, and Correspondence Between Static and Dynamic Data

The study tested (a) the extent to which an inverted-U pattern of fear response predicted persuasion, (b) the degree to which the fear curve mediated the effects of the four components of threat appeals on persuasion, (c) the correspondence between the static measures of fear used in between-subjects designs and the dynamic indices required by the within-subject approach, and (d) the methodological threats inherent to dynamic designs. Participants (N = 418) read a message that advocated for colorectal cancer screening. Results showed that the inverted-U fear curve predicted intention to obtain a colonoscopy, and that susceptibility and response efficacy exerted their influence on persuasion via the fear curve while severity and self-efficacy did not. The static measure of fear showed poor absolute correspondence with the peak and end indices of dynamic fear, but strong pattern correspondence. Hazards to inference posed by dynamic designs of the type used in this study appear negligible.
Serendipity rendezvous as a mitigation of exploration's interruptibility for a team of robots

Dependence on a team of robots to carry out the exploration missions has many benefits such as speeding up the missions; provided that the coordination among robots is maintained. Many circumstances can limit the communication, which is crucial for the coordination among robots (e.g. impenetrable barriers, high temperature etc.). A periodic rendezvous strategy is considered in this paper as a work around in order to overlap communication ranges of the robots. Attending these periodic rendezvous sessions requires that the robots interrupt their current exploration progress periodically and traverse back to the rendezvous points (i.e. Interruptibility). During their trips to these points, they do not gain new knowledge since they cross already explored parts of the area. Therefore, using rendezvous strategies improves the team behavior but has a negative impact on the time efficiency. The contribution of this paper is to mitigate this negative impact of Interruptibility on explorations while maintaining the coordination among robots. The mitigation algorithm is evaluated on several graphs and its performance is compared with other rendezvous approaches where the results are promising.
Migration and cultural diversity challenges in the 21st century

In this discussion we will consider some of the literature that seeks to take stock of the challenges and opportunities for liberal citizenship regimes that follow processes of migration; a body of thought that has variously centred on ways to reconcile political unity with ethnic, cultural and religious difference (e.g., Young, 1990; Taylor, 1992; Kymlicka, 1995; Parekh, 2000; Modood, 2007). In addition to this prevailing ‘canon’ there is a sustained and interdisciplinary body of theory and research exploring configurations of national membership, within and across a number of European polities, especially in terms of citizenship and national identity (e.g., Brubaker, 2001; Joppke, 2004; Koopmans et al, 2005; Banting and Kymlicka, 2006; Jacobs and Rea, 2007; Uberoi; 2008; Joppke, 2009; Meer, 2010; Faas, 2010; Triandafyllidou et al, 2011; Modood, 2013). We begin by noting the perpetual role that migration plays in unsettl ing existing configurations, before elaborating a rationale for remaking forms of collective memb ership in a manner that includes new groups too. Multiculturalism, we argue, is the foremost example of this even though its political fate remains uncertain. To support our reading we positively contrast it with categories such as interculturalism and superdiversity.
Simulating the local behavior of small pedestrian groups using synthetic-vision based steering approach

With the development of Computer Graphics and Virtual Reality technology, crowds in the virtual worlds have become increasingly lively and appealing. However, few existing methods take into account that pedestrians usually walk in small groups of twos and threes in real life, for instance, shopping couples and partners. Our research is based on dynamic behavior of small groups and the interaction between them. By using synthetic-vision based steering approach, combining with formation characteristics and deformation mode of small groups, we propose an approach to simulate the local behavior of small groups. Experiments show that our method can reproduce the local behavior of small groups in real life.
Ensino e aprendizagem na sociedade do entretenimento: desafios para a formação docente Teaching and learning in the entertainment society: challenges for teacher training

This article aims to discuss and question the learning of young people in society of entertainment as well as analyze the possible challenges for teacher education in a society mediated by digital technology of information and communication (TDIC). The centrality of leisure and entertainment in contemporary life reconfigures the teaching strategies and learning school. However, the school, for being the place of tradition and systematic learning, finds it difficult to face this problem, since there are obstacles to higher initial teacher training, in a perspective of incorporating different language media in this process. Finally, the paper explores possible paths to these training practices at the risk of his absence to increase the fragility of the school face the transformations derived from TDIC.