Miracle-dz/UniFAR-FTUs huggingface dataset:
Studying Celebrity Engagement on Social Media: An Indian Experience

Leveraging a celebrity for instant recognition and visibility or building significant brand credibility and driving sales has been a long-established recipe for success over the years. Engaging a reputed face for brand promotion has ever been an exorbitant investment. Digital or social media as a communication platform has not only driven brands to create a desired recall without the burden of unreasonable spends, but has also strengthened and empowered celebrity engagement like never before by throwing a versatile array of options for individual branding and visibility. This chapter aims to explore and analyse the engagement of celebrity on different social media platforms like Facebook and Instagram, Twitter etc. with special reference to Bollywood. It delves into understanding the engagement patterns; aspects of celebrity evoked; brand impact; media celebrity brand fit, and intended target audience whether it leads to action or Influences perceptions.
Multi-Sensor Coordination And Fusion For Automotive Safety Applications

This paper focuses on the solution of the problem of (onboard moving vehicles) multiple sensor data fusion systems. The proposed application uses distributed architectures that operate with sensors or sensor systems and give redundant or complementary information for moving objects. This architecture ensures a modular approach allowing exchangeability and benchmarking using the output of individual trackers, whereas the fusion algorithm gives a solution to the track management problem and the coverage of wide perception areas. The test case is a multi-sensor configuration, which monitors the rear and lateral areas of traffic. Results from simulations and real data show that the given approach allows maintenance of the ID of objects and recognition of the vehicle environment with acceptable rates of false alarm and misses
FC2Q: exploiting fuzzy control in server consolidation for cloud applications with SLA constraints

Modern cloud data centers rely on server consolidation (the allocation of several virtual machines on the same physical host) to minimize their costs. Choosing the right consolidation level (how many and which virtual machines are assigned to a physical server) is a challenging problem, because contemporary multitier cloud applications must meet service level agreements in face of highly dynamic, nonstationary, and bursty workloads. In this paper, we deal with the problem of achieving the best consolidation level that can be attained without violating application service level agreements. We tackle this problem by devising fuzzy controller for consolidation and QoS (FC2Q), a resource management framework exploiting feedback fuzzy logic control, that is able to dynamically adapt the physical CPU capacity allocated to the tiers of an application in order to precisely match the needs induced by the intensity of its current workload. We implement FC2Q on a real testbed and use this implementation to demonstrate its ability of meeting the aforementioned goals by means of a thorough experimental evaluation, carried out with real‐world cloud applications and workloads. Furthermore, we compare the performance achieved by FC2Q against those attained by existing state‐of‐the‐art alternative solutions, and we show that FC2Q works better than them in all the considered experimental scenarios. Copyright © 2014 John Wiley & Sons, Ltd.
Distinct Poly(rC) Binding Protein KH Domain Determinants for Poliovirus Translation Initiation and Viral RNA Replication

ABSTRACT The limited coding capacity of picornavirus genomic RNAs necessitates utilization of host cell factors in the completion of an infectious cycle. One host protein that plays a role in both translation initiation and viral RNA synthesis is poly(rC) binding protein 2 (PCBP2). For picornavirus RNAs containing type I internal ribosome entry site (IRES) elements, PCBP2 binds the major stem-loop structure (stem-loop IV) in the IRES and is essential for translation initiation. Additionally, the binding of PCBP2 to the 5′-terminal stem-loop structure (stem-loop I or cloverleaf) in concert with viral protein 3CD is required for initiation of RNA synthesis directed by poliovirus replication complexes. PCBP1, a highly homologous isoform of PCBP2, binds to poliovirus stem-loop I with an affinity similar to that of PCBP2; however, PCBP1 has reduced affinity for stem-loop IV. Using a dicistronic poliovirus RNA, we were able to functionally uncouple translation and RNA replication in PCBP-depleted extracts. Our results demonstrate that PCBP1 rescues RNA replication but is not able to rescue translation initiation. We have also generated mutated versions of PCBP2 containing site-directed lesions in each of the three RNA-binding domains. Specific defects in RNA binding to either stem-loop I and/or stem-loop IV suggest that these domains may have differential functions in translation and RNA replication. These predictions were confirmed in functional assays that allow separation of RNA replication activities from translation. Our data have implications for differential picornavirus template utilization during viral translation and RNA replication and suggest that specific PCBP2 domains may have distinct roles in these activities.
The Skin Microbiome: Is It Affected by UV-induced Immune Suppression?

Human skin apart from functioning as a physical barricade to stop the entry of pathogens, also hosts innumerable commensal organisms. The skin cells and the immune system constantly interact with microbes, to maintain cutaneous homeostasis, despite the challenges offered by various environmental factors. A major environmental factor affecting the skin is ultraviolet radiation (UV-R) from sunlight. UV-R is well known to modulate the immune system, which can be both beneficial and deleterious. By targeting the cells and molecules within skin, UV-R can trigger the production and release of antimicrobial peptides, affect the innate immune system and ultimately suppress the adaptive cellular immune response. This can contribute to skin carcinogenesis and the promotion of infectious agents such as herpes simplex virus and possibly others. On the other hand, a UV-established immunosuppressive environment may protect against the induction of immunologically mediated skin diseases including some of photodermatoses such as polymorphic light eruption. In this article, we share our perspective about the possibility that UV-induced immune suppression may alter the landscape of the skin’s microbiome and its components. Alternatively, or in concert with this, direct UV-induced DNA and membrane damage to the microbiome may result in pathogen associated molecular patterns (PAMPs) that interfere with UV-induced immune suppression.
Enhanced Approach to Detection of SQL Injection Attack

In recent years, many financial sectors are evolving with huge numbers of web applications, which plays a crucial role in organizations to make important decisions. Considering this, the data has to be secured in order to prevent it from any attacks which lead to a huge loss. One of the topmost attacks in the database is SQL injection attack, is injecting some malicious query into the database causing serious threats. This paper proposes an enhanced approach to dynamic query matching technique by imposing a sanitizer for quick and easy detection of attack.
Test case prioritization based on requirement correlations

Test case prioritization technique aims to improve test efficiency rate by sorting test cases according to some specific criteria. Requirements play an important role throughout software testing. This paper proposes a test case prioritization method based on requirement correlations. Prioritization of requirements is defined by the users and the developers. This technique focuses on requirements with detected faults after the last regression testing. By readjusting prioritization of fault-related requirements, it can optimize the order of test cases. Experimental results show that this technique exactly contributes to achieving high testing efficiency.
Proprioceptive Input to Feeding Motor Programs inAplysia

Although central pattern generators (CPGs) can produce rhythmic activity in isolation, it is now generally accepted that under physiological conditions information from the external and internal environment is incorporated into CPG-induced motor programs. Experimentally advantageous invertebrate preparations may be particularly useful for studies that seek to characterize the cellular mechanisms that make this possible. In these experiments, we study sensorimotor integration in the feeding circuitry of the molluscAplysia. We show that a premotor neuron with plateau properties, B51, is important for generating the radula closing/retraction phase of ingestive motor programs. When B51 is depolarized in semi-intact preparations, radula closing/retractions are enhanced. When B51 is hyperpolarized, radula closing/retractions are reduced in size. In addition to being important as a premotor interneuron, B51 is also a sensory neuron that is activated when the feeding apparatus, the radula, rotates backward. The number of centripetal spikes in B51 is increased if the resistance to backward rotation is increased. Thus, B51 is a proprioceptor that is likely to be part of a feedback loop that insures that food will be moved into the buccal cavity when difficulty is encountered. Our data suggest, therefore, that Aplysia are able to adjust feeding motor programs to accommodate the specific qualities of the food ingested because at least one of the neurons that generates the basic ingestive motor program also serves as an on-line monitor of the success of radula movements.
The Fate of the Tumor in the Hands of Microenvironment: Role of TAMs and mTOR Pathway

Since 2000, written with elegance and accuracy, Hanahan and Weinberg have proposed six major hallmarks of cancer and, together, they provide great advances to the understanding of tumoral biology. Our knowledge about tumor behavior has improved and the investigators have now recognized that inflammatory microenvironment may be a new feature for the tumor entities. Macrophages are considered as an important component of tumoral microenvironment. Biologically, two forms of activated macrophages can be observed: classically activated macrophages (M1) and alternative activated macrophages (M2). Despite the canonical pathways that control this puzzle of macrophages polarization, recently, mTOR signaling pathway has been implicated as an important piece in determining the metabolic and functional differentiation of M1 and M2 profiles. Currently, it is believed that macrophages related to tumoral microenvironment present an “M2-like” feature promoting an immunosuppressive microenvironment enhancing tumoral angiogenesis, growth, and metastasis. In the present review we discuss the role of macrophages in the tumor microenvironment and the role of mTOR pathway in M1 and M2 differentiation. We also discuss the recent findings in M1 and M2 polarization as a possible target in the cancer therapy.
Collaborative BIM in the Cloud and the Communication Tools to Support it

Process in the AEC industry is characterised by the distributed and temporary nature of project teams; discipline specific teams engage in a highly collaborative process with not yet fully standardised requirements for information exchange which often results in chaotic communication patterns. This collaborative process makes communication and coordination challenging and intensifies the need for sophisticated software tools. Efforts to address some of the UK construction industry's problems have seen rapid acceleration of BIM adoption in recent years. The exchange of interoperable building information models across teams provides the opportunity for an improved communication paradigm, where the "structured model" rather than the "document" acts as the focal unit of communication. Since collaborators are geographically distributed, this communication type finds its natural environment in online collaboration platforms hosting building information models. Effective collaboration requires coordinated communication and communicated coordination. BIM can be expressed as the "language of construction" and requires structure and standardization even on the human communication level. The life-cycle approach will pose additional collaboration requirements. Integrated, intuitive communication tools for BIM should replace e-mail. A preliminary analysis of data from the usage of online collaboration software, including network graph representations, provides some insight into usage patterns and serves as a basis for similar analyses as more of project data becomes available. Improved results would come from a better designed analysis of more projects.
Opportunistic screening of atrial fibrillation by automatic blood pressure measurement in the community

Objective Timely detection of atrial fibrillation (AF) may effectively prevent cardiovascular consequences. However, traditional diagnostic tools are either poorly reliable (pulse palpation) or not readily accessible (ECG) in general practice. We tested whether an automatic oscillometric blood pressure (BP) monitor embedded with an algorithm for AF detection might be effective for opportunistic screening of asymptomatic AF in the community. Setting A community-based screening campaign in an unselected population to verify the feasibility of AF screening with a Microlife WatchBP Office BP monitor with a patented AFIB algorithm. When possible AF was detected (≥2 of 3 BP measurements reporting AF), a doctor immediately performed a single-lead ECG in order to confirm or exclude the presence of the arrhythmia. The main demographic and clinical data were also collected. Participants 220 consecutive participants from an unselected sample of individuals in a small Italian community. Primary and secondary outcome measures Number of patients detected with AF and diagnosed risk factors for AF. Results In 12 of 220 participants, the device detected possible AF during the BP measurement: in 4 of them (1.8%), the arrhythmia was confirmed by the ECG. Patients with AF were more likely to be older (77.0±1.2 vs 57.2±15.2 years, p=0.010), obese (50.0 vs 14.4%, p=0.048) and to suffer from a cardiovascular disease (50.0 vs 10.6%, p=0.014) than patients without AF. Participants with a positive BP AF reading and non-AF arrhythmias (n=8) did not differ in their general characteristics from participants with a negative BP AF reading and were younger than patients with AF (mean age 56.4±14.8, p=0.027; 5 of 8 participants aged <65 years). Conclusions Opportunistic screening of AF by BP measurement is feasible to diagnose this arrhythmia in unaware participants, particularly in those older than 65 years, who are the target patient group recommended by current AF screening guidelines.
LOW POWER CMOS OUTPUT CELL DESIGN WITH SPIKE FILTERING FOR BASEBAND DIGITAL SIGNAL PROCESSING

A novel power-saving and small-area digital output cell is proposed in this work. The new cell drastically reduces the output power consumption by filtering pre-defined spikes, which have been considered as one of the major power dissipation sources of the whole chip, with little sacrifice of speed or delay. The duration of the spikes to be removed can be pre-defined either dynamically by digital selection signals or permanently by fuses to be burned. The maximum operating clock is 200 MHz given a 10 pF off-chip load according to measurements on silicon. Not only the proposed design removes hostile spikes to baseband DSP modules, it also reduces unwanted power dissipation caused by the spikes.
Low Power Continuous-time Bandpass Delta-Sigma Modulators.

2012 ii To Dad, Mom, my brother, and friends. iii ACKNOWLEDGEMENTS I would like to thank my advisor Prof. Michael Flynn for guiding and encouraging me technically and personally during the whole time in Ann Arbor. He inspired and motivated me with his passion and intelligence, and I would never have been able to finish my research without his care and support. I also would like to thank my committee members, Prof. Analog Devices. I learned a lot from them while my internship in Analog Devices, and my research was successful thanks to their advice and generous support. And I would like to acknowledge my best friend Dr. Sungwook Chang who always showed the best of friendship for 15 years and other friends: Kihyuk Son. All of them not only gave me unforgettable memories in Ann Arbor but also helped my research greatly. iv I would like to thank my former and current research group members who are always good mentors as well as sincere friends: Dr. And I am also very grateful to Korean Foundation for advanced studies (KFAS) for providing me with a fellowship and other supports. Finally, I would like to thank my family. My father, mother, and brother gave me their endless love and support, and they are a big part of my success.
Early Experiences with Persistent Java

This paper reports on initial experiences with an orthogonally persistent variant of the Java platform, called Persistent Java (PJava). We review and reflect on the design of PJava and discuss compatibility with Java. The features and limitations of an initial prototype are discussed. The experiences gained in running four distinct applications on PJava are described in detail.
Degradation of Three Aromatic Dyes by White Rot Fungi and the Production of Ligninolytic Enzymes

This study was conducted to evaluate the degradation of aromatic dyes and the production of ligninolytic enzymes by 10 white rot fungi. The results of this study revealed that Pycnoporus cinnabarinus, Pleurotus pulmonarius, Ganoderma lucidum, Trametes suaveolens, Stereum ostrea and Fomes fomentarius have the ability to efficiently degrade congo red on solid media. However, malachite green inhibited the mycelial growth of these organisms. Therefore, they did not effectively decolorize malachite green on solid media. However, P. cinnabarinus and P. pulmonarius were able to effectively decolorize malachite green on solid media. T. suaveolens and F. rosea decolorized methylene blue more effectively than any of the other fungi evaluated in this study. In liquid culture, G. lucidum, P. cinnabarinus, Naematoloma fasciculare and Pycnoporus coccineus were found to have a greater ability to decolorize congo red. In addition, P. cinnabarinus, G. lucidum and T. suaveolens decolorized methylene blue in liquid media more effectively than any of the other organisms evaluated in this study. Only F. fomentarius was able to decolorize malachite green in liquid media, and its ability to do so was limited. To investigate the production of ligninolytic enzymes in media containing aromatic compounds, fungi were cultured in naphthalene supplemented liquid media. P. coccineus, Coriolus versicolor and P. cinnabarinus were found to produce a large amount of laccase when grown in medium that contained napthalene.
A Comparison of Eight Methods for the Dual‐Endpoint Evaluation of Efficacy in a Proof‐of‐Concept HIV Vaccine Trial

Summary To support the design of the world's first proof‐of‐concept (POC) efficacy trial of a cell‐mediated immunity‐based HIV vaccine, we evaluate eight methods for testing the composite null hypothesis of no‐vaccine effect on either the incidence of HIV infection or the viral load set point among those infected, relative to placebo. The first two methods use a single test applied to the actual values or ranks of a burden‐of‐illness (BOI) outcome that combines the infection and viral load endpoints. The other six methods combine separate tests for the two endpoints using unweighted or weighted versions of the two‐part z, Simes', and Fisher's methods. Based on extensive simulations that were used to design the landmark POC trial, the BOI methods are shown to have generally low power for rejecting the composite null hypothesis (and hence advancing the vaccine to a subsequent large‐scale efficacy trial). The unweighted Simes' and Fisher's combination methods perform best overall. Importantly, this conclusion holds even after the test for the viral load component is adjusted for bias that can be introduced by conditioning on a postrandomization event (HIV infection). The adjustment is derived using a selection bias model based on the principal stratification framework of causal inference.
A robust mosaic panorama technique for video

Digital image mosaic can be defined as image registration and fusion of lots of overlapping digital images or multiple video frames into a single wide field of view image or dynamic panoramic image. It is brought for the limitation of camera visual angle, which is impossible to shoot a panorama image once. So the research of such a robust mosaic panorama technique for video is necessary and possible. In this paper, a robust mosaic panorama technique for video is proposed. We describe the panorama mosaic process, involving the following main tasks. At the start, we describe the feature-based motion estimator to obtain the video motion parameters. After that, for the purpose of removing the foreground objects, the input frames are combined into the panorama. Experimental results show the proposed method can be successfully provided with the video mosaic panorama capability.
Segmentation of Intervertebral Discs , Trachea and Spinal Cord from MRI Images

For preoperative planning and intraoperative support, segmentation of soft tissue structures from the cervical region is a prerequisite. Main activities have been started in the past to segment vertebrae from CT images. But soft tissue structures have been neglected. There is only little research work about segmentation of the spinal chord and the trachea, however as far as we know there is no work about segmentation of intervertebral discs. In this paper a new segmentation method is presented for cervical discs, trachea and the spinal chord. The approach implements a continuous process, which uses neighboring information and medical knowledge to accomplish automatic segmentation. Even seed points are not needed since localization of the discs is done using a generalized Hough transform and a cluster analysis. Additionally, for a complete view of the cervical region a rule based analyzer algorithm is briefly presented, which uses anatomical knowledge to find out attachment points on the surface of the cervical vertebrae.
Virtual Worlds for Serious Applications ( VS-GAMES ' 12 ) The Design Principles for Flow Experience in Educational Games

Educational games have to be well designed to incorporate learner engagement, an integral component of educational effectiveness. One foundation of designing educational engagement is flow theory. This article presents a flow framework that describes the building blocks of flow experience that can be used to design appealing and effective educational games for formal and informal learning contexts. The framework provides the principles for good educational game design, based upon associative, cognitive and situative learning theories, including engagement and pedagogic elements with a focus upon feedback and flow principles. Furthermore, the paper clarifies the relation between the flow experience and immersion. We tested the flow framework in the RealGame case study, which revealed that the RealGame business simulation game was high and the findings indicated that sense of control, clear goals and challenge-skill dimensions of flow scored the highest, but a rewarding experience and feedback dimensions also scored highly by the students. Overall, the results indicate that flow framework is a useful tool in studying game-based learning experiences. © 2012 The Authors. Published by Elsevier B.V. Selection and/or peer-review under responsibility of the scientific programme committee of VS-Games 2012