Miracle-dz/UniFAR-FTUs huggingface dataset:
TRANSPARENCY ANALYSIS OF FIRST-ORDER TAKAGI-SUGENO SYSTEMS

The primary goal of this paper is to investigate transparency properties of Takagi-Sugeno (TS) systems. TS systems, distinguished by half-linguistic/half-functional rules are exploited in numerous applications today and deserve special attention from transparency viewpoint. The fact that TS systems can be interpreted in terms of local linear models is generally acknowledged. Few authors, however, have been interested with the question if this interpretation can be considered accurate (i.e. if the system is transparent). In this paper, the problem is taken into consideration and transparency measure for 1 order TS systems is introduced. Included are examples of TS modeling demonstrating that transparency and adaptability of TS systems are of somewhat exclusive character.
A Novel Hybridization of Expectation-Maximization and K-Means Algorithms for Better Clustering Performance

Expectation Maximization (EM) is a widely employed mixture model-based data clustering algorithm and produces exceptionally good results. However, many researchers reported that the EM algorithm requires huge computational efforts than other clustering algorithms. This paper presents an algorithm for the novel hybridization of EM and K-Means techniques for achieving better clustering performance (NovHbEMKM). This algorithm first performs K-Means and then using these results it performs EM and K-Means in the alternative iterations. Along with the NovHbEMKM, experiments are carried out with the algorithms for EM, EM using the results of K-Means and Cluster package of Purdue University. Experiments are carried out with datasets from UCI ML repository and synthetic datasets. Execution time, Clustering Fitness and Sum of Squared Errors (SSE) are computed as performance criteria. In all the experiments the proposed NovHbEMKM algorithm is taking less execution time by producing results with higher clustering fitness and lesser SSE than other algorithms including the Cluster package.
Mindfulness training for medical and psychology students

Background: Distress and burnout among medical and psychology professionals are commonly reported and have implications for the quality of patient care delivered. Already in the course of university studies, medicine and psychology students report mental distress and low life satisfaction. There is a need for interventions that promote better coping skills in students in order to prevent distress and future burnout. This study examines the effect of a seven-week Mindfulness-Based Stress Reduction (MBSR) programme on mental distress, study stress, burnout, subjective well-being, and mindfulness of medical and psychology students. Methods: A total of 288 students (mean age = 23 years, 76% female) from the University of Oslo and the University of Tromsø were randomly allocated to an intervention or control group. The control group continued with their standard university courses and received no intervention. Participants were evaluated using self-reported measures both before and after the intervention. These were: the ‘General Health Questionnaire, Maslach Burnout Inventory Student version, Perceived Medical School Stress, Subjective Well-being, and Five Facet Mindfulness Questionnaire’ and additional indices of compliance. Results: Following the intervention, a moderate effect on mental distress (Hedges’g 0.65, CI = .41, .88), and a small effect on both subjective well-being (Hedges’g 0.40, CI = .27, .63) and the mindfulness facet ‘non-reacting’ (Hedges’g 0.33, CI = .10, .56) were found in the intervention group compared with the control group. A higher level of programme attendance and reported mindfulness exercises predicted these changes. Significant effects were only found for female students who additionally reported reduced study stress and an increase in the mindfulness facet ‘non-judging’. Gender specific effects of participation in the MBSR programme have not previously been reported, and gender differences in the present study are discussed. Conclusion: Female medical and psychology students experienced significant positive improvements in mental distress, study stress, subjective well-being and mindfulness after participating in the MBSR programme. Trial registration: NCT00892138
Misunderstood misunderstanding: social identities and public uptake of science

This paper draws general insights into the public reception of scientific knowledge from a case study of Cumbrian sheep farmers' responses to scientific advice about the restrictions introduced after the Chernobyl radioactive fallout. The analysis identifies several substantive factors which influence the credibility of scientific communication. Starting from the now-accepted point that public uptake of science depends primarily upon the trust and credibility public groups are prepared to invest in scientific institutions and representatives, the paper observes that these are contingent upon the social relationships and identities which people feel to be affected by scientific knowledge, which never comes free of social interests or implications. The case study shows laypeople capable of extensive informal reflection upon their social relationships towards scientific experts, and on the epistemological status of their own `local' knowledge in relation to `outside' knowledge. Public uptake of science might be improved if scientific institutions expressed an equivalent reflexive discourse in the public domain.
Type IIB orientifolds without untwisted tadpoles, and non-BPS D-branes

We discuss the construction of six- and four-dimensional type-IIB ori- entifoldswithvanishinguntwistedRRtadpoles,butgenericallynon-zerotwistedRR tadpoles. Tadpole cancellation requires the introduction of D-brane systems with zero untwisted RR charge, but non-zero twisted RR charges. We construct explicit models containing branes and antibranes at xed points of the internal space, or non-BPS branes partially wrapped on it. The models are non-supersymmetric, but are absolutely stable against decay to supersymmetric vacua. For particular values of the compactication radii tachyonic modes may develop, triggering phase tran- sitions between the dierent types of non-BPS congurations of branes, which we study in detail in a particular example. As an interesting spin-o, we show that the T 6 =Z4orientifoldwithoutvectorstructure,previously consideredinconsistent dueto uncancelable twisted tadpoles, can actually be made consistent by introducing a set of brane-antibrane pairs whose twisted charge cancels the problematic tadpole.
Using Supertags in Document Filtering: the Eeect of Increased Context on Information Retrieval Eeectiveness

The syntactic information latent in any coherent text can be exploited to overcome some inadequacies of keyword-based retrieval and make information retrieval more e ective. We have earlier quantitatively demonstrated how syntactic information is useful in ltering out irrelevant documents. We have implemented a system which exploits a rich syntactic representation of supertags in a exible manner to lter documents for relevance. The system has been tested on a large collection of newswire sentences, and achieves recall and precision gures of 88% and 97% for ltering out irrelevant documents. Its performance and modularity makes it a promising postprocessing addition to any Information Retrieval system. In this paper we examine how the performance of this system is a ected by varying the context provided to the system and show that the experimentally determined optimal size of the context validates linguistic intuitions.
Aesthetics and preferences of web pages

The first impressions of web pages presented to users was investigated by using 13 different web pages, three types of scales and 18 participants. Multidimensional analysis of similarity and preference judgements found four important dimensions: beauty, mostly illustrations versus mostly text, overview and structure. Category scales indicated the existence of two factors related to formal aspects and to appeal of the objects, respectively. The best predictor for the overall judgement of the category scales was beauty. Property vector fitting of the multidimensional solutions with the category scales further indicated the importance of beauty for the preference space. Aspects of usability, product design and aesthetics are discussed.
The emerging role of 5-hydroxymethylcytosine in neurodegenerative diseases

DNA methylation primarily occurs within human cells as a 5-methylcytosine (5mC) modification of the cytosine bases in CpG dinucleotides. 5mC has proven to be an important epigenetic mark that is involved in the control of gene transcription for processes such as development and differentiation. However, recent studies have identified an alternative modification, 5-hydroxymethylcytosine (5hmC), which is formed by oxidation of 5mC by ten-eleven translocation (TET) enzymes. The overall levels of 5hmC in the mammalian genome are approximately 10% of 5mC levels, although higher levels have been detected in tissues of the central nervous system (CNS). The functions of 5hmC are not yet fully known, but evidence suggests that 5hmC may be both an intermediate product during the removal of 5mC by passive or active demethylation processes and also an epigenetic modification in its own right, regulating chromatin or transcriptional factors involved in processes such as neurodevelopment or environmental stress response. This review highlights our current understanding of the role that 5hmC plays in neurodegenerative diseases, including Alzheimer's disease (AD), amyotrophic lateral sclerosis (ALS), fragile X-associated tremor/ataxia syndrome (FXTAS), Friedreich ataxia (FRDA), Huntington's disease (HD), and Parkinson's disease (PD).
Interference cancellation in multiuser hybrid overlay cognitive radio

In this paper, we consider an overlay cognitive radio (CR) consisting of a primary macro-cell and cognitive small cells of cooperative secondary base stations (SBS). We suggest studying a hybrid CR where a filter bank multicarrier (FBMC) is used for the secondary users (SU) whereas the primary users (PU) are based on orthogonal frequency division multiplexing (OFDM). Compared to OFDM, FBMC has the advantage of reducing the SU interference level that is induced by the differences between the SBS and PU carrier frequency offsets (CFO). Our contribution is threefold: 1/ we derive the interference expression due to SU at the PU receiver, 2/ we propose to use zero forcing beamforming (ZFBF) to cancel the interference, 3/ a comparative study with CR based on OFDM for both the PU and the SU confirms the efficiency of the proposed scheme.
Robust visual tracking via binocular multi-task multi-view joint sparse representation

Visual object tracking has been a major and fundamental topic in computer vision field for decades. Despite of great progress that has been made, robust tracking under drastic illumination changes, continuous occlusions and scale changes remains a very challenging work. In this paper, an efficient binocular object tracker via joint sparse representation is proposed as Binocular Multi-task Multi-view Tracker (BMTMVT). By introducing the unit-norm normalized 3D depth feature into previous multiple 2D views (such as intensity, color, texture and edge) based sparse representation framework, tracking performance is significantly improved. Meanwhile, an approach for occlusion detection utilizing depth based histogram analysis is further proposed to efficiently decide the accurate time to update target template set. Besides, a strategy of particles pretreatment and a screening process are introduced to enhance the particles efficiency and to optimize tracking performance with employing range data respectively. Extensive experiments on various types of challenging sequences from KITTI and Princeton data sets demonstrate that the proposed BMTMVT algorithm outperforms the state-of-the-art trackers, especially when handling frequently changing illuminations, successive obstructions and variations in scale.
A distinct cohort of the TGFβ superfamily members expressed in human endometrium regulate decidualization

BACKGROUND Successful blastocyst implantation requires the differentiation of human endometrial stromal cells (HESC), a process known as decidualization. Activin A, a transforming growth factor β (TGFβ) superfamily member, enhances HESC decidualization and localizes to decidual cells in human endometrium. Other TGFβ superfamily members, including BMP2, BMP4, BMP7, GDF5, GDF8, GDF11, TGFβs and Nodal, may also play a role during decidualization. This study aimed to identify these TGFβ family members in human endometrium, and to determine whether they are involved in human decidualization. METHODS Protein localization of TGFβ family members was examined in secretory phase human endometrium and first trimester decidua by immunohistochemistry. mRNA expression was examined in HESC. Activin inhibitors (Activin-M108A/SB431542) with differing specificities for the other TGFβ members under consideration were applied during HESC decidualization in vitro. The secretion levels of potential TGFβ superfamily members were measured during decidualization, and recombinant proteins added to examine their effect. RESULTS This study has identified BMP2, BMP4, BMP7, GDF5, GDF8 and GDF11 but not Nodal in secretory phase human endometrium, but only BMP2, GDF5 and TGFβ1 protein were detected in decidual cells. All ligands except Nodal were expressed by cultured HESC. Both inhibitors significantly reduced decidualization validating the role of activin, but potentially also other TGFβ members, during decidualization. BMP2 and TGFβ1 secretion increased during HESC decidualisation and exogenous administration of these proteins significantly enhanced decidualization in vitro. CONCLUSIONS Like activin, BMP2 and TGFβ1 are likely to be involved in HESC decidualization. This is the first study to identify and localize BMP4, BMP7, GDF5, GDF8 and GDF11 in secretory phase human endometrium. Understanding the factors critical for the implantation process is needed for improving fertility and pregnancy outcomes.
Performance Evaluation of AES Targeting a High-End DSP

Efficient implementation of block ciphers is critical towards achieving both high security and high-speed processing. Numerous block ciphers, such as the Advanced Encryption Standard, have been proposed and implemented targeting a wide range of general purpose processors. It is therefore of interest to evaluate the performance of block ciphers on different types of processors to determine their implementation suitability. In October of 2000, NIST chose Rjindael as the Advanced Encryption Standard and thus the evaluation of Rijndael performance is of high interest. This work evaluates the performance of Rijndael targeting the Texas Instruments (TI) TMS320C6713 Floating-Point Digital Signal Processor (DSP). In addition, we compare the measured performance results to results obtained targeting the TI TMS320C6201 Floating-Point DSP in an effort to provide a more complete performance analysis when targeting the TI C6x family of DSPs.
An evaluation of Internet banking in New Zealand

This paper examines how New Zealand banks enhance their retail banking services through the Internet. Seven NZ online banks were studied in terms of their web sites' effectiveness, functionalities and Internet strategies. The functionality was examined by evaluating banks' web sites using a tailored electronic commerce model. The effectiveness was surveyed utilising a judgment sample of actual and potential retail Internet banking customers. Main factors that inhibit the adoption of I-banking in NZ are security, doubt about the complication of Internet banking and the ability to bank using other facilities. Other important factors that customers use to judge the performance of retail I-banking services are response time, services free from technical problems and up-to-date information. NZ banks perform extremely well in providing up-to-date information. However, further improvements on security, download time, response time and the ability to provide services free from technical problems should be considered in order to satisfy customers' requirements.
YB-1 Is Important for Late-Stage Embryonic Development, Optimal Cellular Stress Responses, and the Prevention of Premature Senescence

ABSTRACT Proteins containing “cold shock” domains belong to the most evolutionarily conserved family of nucleic acid-binding proteins known among bacteria, plants, and animals. One of these proteins, YB-1, is widely expressed throughout development and has been implicated as a cell survival factor that regulates the transcription and/or translation of many cellular growth and death-related genes. For these reasons, YB-1 deficiency has been predicted to be incompatible with cell survival. However, the majority of YB-1 −/− embryos develop normally up to embryonic day 13.5 (E13.5). After E13.5, YB-1 −/− embryos exhibit severe growth retardation and progressive mortality, revealing a nonredundant role of YB-1 in late embryonic development. Fibroblasts derived from YB-1 −/− embryos displayed a normal rate of protein synthesis and minimal alterations in the transcriptome and proteome but demonstrated reduced abilities to respond to oxidative, genotoxic, and oncogene-induced stresses. YB-1 −/− cells under oxidative stress expressed high levels of the G1-specific CDK inhibitors p16Ink4a and p21Cip1 and senesced prematurely; this defect was corrected by knocking down CDK inhibitor levels with specific small interfering RNAs. These data suggest that YB-1 normally represses the transcription of CDK inhibitors, making it an important component of the cellular stress response signaling pathway.
Randomized Distributed Space Time Codes Using Nakagami-M Fading Channels in Wireless Communication

In this paper, we are presenting the space time coding to analysis the performance of Nakagami-m fading channel in wireless communication. We introduce a class of space time codes known as space time block code. We propose a space time (ST) codes for multi antenna using QAM over Nakagami -m fading channel. Frame error rate and outage probability are the two basic parameters that are used in this paper to analysis the performance of the space time code. To improving the data rate and/or the reliability of communications over fading channels using multiple transmit antennas has been considered. Simulation results show the performance of STC using Frame Error Rate (FER) and outage capacity using 4-QAM and 8-QAM modulation techniques with different number of transmitting and receiving antenna. From the comparative analysis we can also show that as the number of receiver goes on increases frame error rate also goes on decreasing. Result also reveals that the outage capacity of the system increases with increase in SNR. In this paper simulations have been conducted to study the Frame Error Rate (FER) and Outage capacity of Space-Time block Coding with different number of transmit and receive antennas performance of a Nakagami-m fading channel.
Object oriented approach to prefix based fast mining of closed sequential patterns

In recent years, mining of sequential patterns has been studied extensively in various domains. Most of the existing algorithms find patterns in transactional databases. This paper proposes a novel algorithm to mine closed sequential patterns using an inverted matrix and prefix based sequence element matrix. Inverted matrix minimizes the search space for discovering various sequential patterns of different items. We use a prefix based sequence element matrix to minimize the scans required at levels k and k+1 in the mining process. Our experimental results show the performance improvement of the new algorithm over the various algorithms.
Maximum torque control of SynRM drive using ALM-FNN controller

The paper is proposed maximum torque control of SynRM drive using adaptive learning mechanism-fuzzy neural network(ALM-FNN) controller and artificial neural network(ANN). The control method is applicable over the entire speed range and considered the limits of the inverter's current and voltage rated value. For each control mode, a condition that determines the optimal d-axis current for maximum torque operation is derived. The proposed control algorithm is applied to SynRM drive system controlled ALM-FNN and ANN controller, the operating characteristics controlled by maximum torque control are examined in detail. Also, this paper is proposed the analysis results to verify the effectiveness of the ALM-FNN and ANN controller.
Inactivation of a Plasmodium apicoplast protein attenuates formation of liver merozoites

Malaria parasites undergo a population expansion inside the host liver before disease onset. Developmental arrest inside host hepatocytes elicits protective immune responses. Therefore, elucidation of the molecular mechanisms leading to mature hepatic merozoites, which initiate the pathogenic blood phase, also informs anti‐malaria vaccine strategies. Using targeted gene deletion in the rodent model malaria parasite Plasmodium berghei, we show that a Plasmodium‐specific Apicoplast protein plays an important role for Liver Merozoite formation (PALM). While the resulting knockout mutants develop normally for most of the life cycle, merozoite release into the blood stream and the ability to establish an infection are severely impaired. Presence of a signature blood‐stage antigen, merozoite surface protein 1 and normal apicoplast morphology indicate that the inability to finalize merozoite segregation is a direct consequence of loss of PALM function. Experimental immunization of mice with as few as two doses of palm‐ sporozoites can elicit sterile protection up to 110 days after final immunization. Our data establish that a tailor‐made arrest in the final steps of hepatic merozoite formation can induce strong protective immune responses and that malaria parasites employ a distinct apicoplast protein for efficient formation of pre‐erythrocytic merozoites.
Evidence for the Coupling of ATP Hydrolysis to the Final (Extension) Phase of RecA Protein-mediated DNA Strand Exchange (*)

RecA protein promotes a limited DNA strand exchange reaction, without ATP hydrolysis, that typically results in formation of short (1-2 kilobase pairs) regions of hybrid DNA. This nascent hybrid DNA is extended in a reaction that can be coupled to ATP hydrolysis. When ATP is hydrolyzed, the extension phase is progressive and its rate is 380 ± 20 bp min at 37°C. A single RecA nucleoprotein filament can participate in multiple DNA strand exchange reactions concurrently (involving duplex DNA fragments that are homologous to different segments of the DNA within a nucleoprotein filament), with no effect on the observed rate of ATP hydrolysis. The ATP hydrolytic and hybrid DNA extension activities exhibit a dependence on temperature between 25 and 45°C that is, within experimental error, identical. This provides new evidence that the two processes are coupled. Arrhenius activation energies derived from the work are 13.3 ± 1.1 kcal mole for DNA strand exchange, and 14.4 ± 1.4 kcal mole for ATP hydrolysis during strand exchange. The rate of branch movement in the extension phase (base pair min) is related to the k for ATP hydrolysis during strand exchange (min) by a factor equivalent to 18 bp throughout the temperature range examined. The 18-base pair factor conforms to a quantitative prediction derived from a model in which ATP hydrolysis is coupled to a facilitated rotation of the DNA substrates. RecA filaments possess an intrinsic capacity for DNA strand exchange, mediated by binding energy rather than ATP hydrolysis, that is augmented by an ATP-dependent molecular motor.