Miracle-dz/UniFAR-FTUs huggingface dataset:
Protein structure prediction

Owing to significant efforts in genome sequencing over nearly three decades (McPherson et al. 2001; Venter et al. 2001), gene sequences from many organisms have been deduced. Over 100 million nucleotide sequences from over 300 thousand different organisms have been deposited in the major DNA databases, DDBJ/ EMBL/GenBank (Benson et al. 2003; Miyazaki et al. 2003; Kulikova et al. 2004), totaling almost 200 billion nucleotide bases (about the number of stars in the Milky Way). Over 5 million of these nucleotide sequences have been translated into amino acid sequences and deposited in the UniProtKB database (Release 12.8) (Bairoch et al. 2005). The protein sequences in UniParc triple this number. However, the protein sequences themselves are usually insufficient for determining protein function as the biological function of proteins is intrinsically linked to three dimensional protein structure (Skolnick et al. 2000). The most accurate structural characterization of proteins is provided by X-ray crystallography and NMR spectroscopy. Owing to the technical difficulties and labor intensiveness of these methods, the number of protein structures solved by experimental methods lags far behind the accumulation of protein sequences. By the end of 2007, there were 44,272 protein structures deposited in the Protein Data Bank (PDB) (www.rcsb.org) (Berman et al. 2000) − accounting for just one percent of sequences in the UniProtKB database (http://www.ebi.ac.uk/swissprot). Moreover, the gap between the number of protein sequences and the number of structures has been increasing as indicated in Fig. 11.1. One of the major efforts in protein structure determination in recent years is the structural genomics (SG) project initiated at the end of last century (Sali 1998; Terwilliger et al. 1998; Burley et al. 1999; Smaglik 2000; Stevens et al. 2001). The SG project aims to obtain 3D models of all proteins by an optimized combination of experimental
Using participatory research, remote sensing and field surveys to build a state and transition model for the native pastures of northern Uruguay.

Native grasslands cover 55% of the agricultural lands of Uruguay. Balancing conservation, agricultural production and human well-being is a major management challenge. Adaptive management approaches have been developed for leased land, underpinned by a newly developed state and transition model (STM). The model was tested in northern Uruguay, in the Department of Paysandú, covering an area of 8300 ha. Floristic surveys were used to define five states, based on the relative cover of key plant species and functional types. Each state was characterized in terms of livestock density, sheep/cattle ratio and years since last ploughing. Aboveground Net Primary Production (ANPP) data were derived from MODIS NDVI data using the Monteith model. Total production and ANPP, including seasonal and inter-annual variability, were characterized for each state. Hypotheses on the drivers of the transitions between states of degradation were derived from local studies on the effect of grazing and cropping on grassland structure and function. A participatory engagement process with local stakeholders was used to develop actions that focused on managing the heterogeneity of forage resources and the desired transitions between states.
A one-dimensional radiative convective model with detailed cloud microphysics

The Arctic is a key element in determining the radiation budget of the earth. Within the polar regions, the net radiation (incoming solar radiation minus outgoing infrared radiation) is negative. To understand the role this energy deficit plays in the overall radiation budget, one must examine the prevalent atmospheric features of the Arctic. One such feature is a persistent layer of low-altitude, stratiform clouds found over the central Arctic predominantly from April to September. These Arctic stratus clouds (ASC) modulate the earth`s radiation budget by contributing to the vertical transport of heat. It is, therefore, crucial to understand the radiative properties of Arctic stratus clouds. We believe that the radiative properties of ASC are strongly coupled with their cloud microphysics. Our aim is to develop a model that will determine if this coupling is sufficient to describe the observed characteristic properties, such as lifetime and the multi-layered structure, of ASC. In addition, we hope to provide useful input to measurement programs at the Atmospheric Radiation Measurement Program`s North Slope of Alaska site by isolating the measurable parameters that influence the overall radiative properties of ASC. Several features of ASC have been integrated directly into the one-dimensional model currently being developed.more » Generally, ASC cover large areas and exhibit reasonable horizontal homogeneity but extensive vertical inhomogeneities. Therefore, in our model, we have assumed radiative processes are important in determining vertical structure while not considering horizontal transport. In addition, ASC occur in defined, multi-layered structures. This feature of the ASC, in conjunction with their horizontal homogeneity, justifies the use of radiative transfer theory for plane-parallel geometry with multiple scattering. Finally, ASC are generally long-lived and precipitate little during their lifetimes. « less
DIABETIC FOOT: A SCOPING REVIEW OF NEUROSENSORIC DISORDERS – THERMOGRAPHY

Background: Diabetic foot is a chronic complication that can be detrimental and has an impact on the quality of life of diabetic patients. Neurosensory examination of skin temperature using a thermograph can help prevent diabetic foot. Objective: to identify the neurosensory examination of skin temperature using infrared thermographs in addressing the risk of diabetic foot Design: The design in this study is Scoping review Methods: A journal search was conducted using the keywords "infrared thermography, screening or assessment, diabetic foot, and meta-analysis" to collect relevant articles published in the last ten years from four databases (ProQuest, PubMed, ScienceDirect, and Google Scholar). The inclusion criteria were: nurses, patients, diabetic foot, assessment, full-text articles, studies focusing on nursing issues, and written in English. Four journal articles were selected and analyzed using PICO. Results: Four meta-analysis articles on neurosensory examination of skin temperature sensitivity using a thermograph have a p value < 0.05, which can support clinical nursing for monitoring diabetic foot prevention. Conclusion: Examination of skin temperature sensation using a thermograph can be used as a method for neurosensory assessment in monitoring nursing care for structural integrity problems in the physiological changes of the diabetic foot.
Application of Analytic Hierarchy Process in the Selection of Botryococcus braunii Cultivation Technology for Bio-crude Oil Production

Bio-crude oil is a way to utilize bioenergy that can reduce the Indonesian government's dependence on fossil energy. Bio-crude oil can be obtained by carrying out a thermochemical process of biomass. Microalgae is a potential source of biomass and Botryococcus braunii is one of the promising types of microalgae for this matter. One of the units required in the conversion process of microalgae into bio-crude oil is the cultivation unit. The objective of this study is to determine the most effective and optimal cultivation technology to be applied to the bio-crude oil refinery plant. Location of the cultivation system is in Cilacap, Central Java, Indonesia. A study was conducted for this purpose using the Analytic Hierarchy Process (AHP) method. The cultivation systems proposed to be the alternatives were open raceway pond, flat panel photo-bioreactor, hybrid, and membrane photo-bioreactor. The AHP results showed that the open raceway pond was selected to be applied to the bio-crude oil refinery process. The biomass production potential of Botryococcus braunii from the cultivation unit in this study was 19.8795 ton/year/ha which could be processed into 11.5301 ton of bio-crude oil with a high heating value (HHV) of 553,448.8 MJ.
Grey Correlation Analysis of Air Quality and Its Affection Factors in Luoyang City

By using the grey correlation analysis,air quality and its affected factors were studied in Luoyang city.The results showed that from 2006 to 2009,PM_(10) was the major pollutant.The air quality of Luoyang city has a hybrid features,polluted by both coal burning and dust.Total amount emission of dust is the first important factor,and the increase of vehicle is the second factor.Meantime,area of public green per capita and total amount emission of SO_2 also affect the air quality.To improve the air quality of Luoyang city,effective measures should be taken,such as reconstructing the gas consumption structure,controlling the vehicle exhaust emission and enhancing the urban greening.
Bulletin of the American Meteorological Society

Manuscript Number: BAMS-D-14-00176 Full Title: MED-CORDEX initiative for Mediterranean Climate studies. Article Type: Article Corresponding Author: Paolo Ruti, PhD ENEA Roma, ITALY Corresponding Author's Institution: ENEA First Author: Paolo Ruti, PhD Order of Authors: Paolo Ruti, PhD Samuel Somot Filippo Giorgi Clotilde Dubois Emmanouil Flaounas Anika Obermann Alessandro Dell'Aquila Giovanna Pisacane Ali Harzallah Emanuele Lombardi Bodo Ahrens Naveed Akhtar Antoinette Alias Thomas Arsouze Rodriguez raznar@puertos.es Sophie Bastin J Bartholy Karine Beranger Jonathan Beuvier Sophie Bouffies-Cloche Jennifer Brauch William Cabos Sandro Calmanti Jean-Christophe Calvet Adriana Carillo Dario Conte Erika Coppola Vladimir Djurdjevic Philippe Drobinski
A History Of Modern Palestine One Land Two Peoples

a history of modern palestine one land two peoples is available in our book collection an online access to it is set as public so you can download it instantly. Our digital library spans in multiple countries, allowing you to get the most less latency time to download any of our books like this one. Merely said, the a history of modern palestine one land two peoples is universally compatible with any devices to read.
UvA-DARE ( Digital Academic Repository ) Supported Home Ownership and Adult Independence in Milan : The Gilded Cage of Family Housing Gifts and Transfers

This article analyses practices of intergenerational support for homeownership among different generations of families in Milan, Italy, highlighting the role of housing in family welfare relations and life-course transitions. It makes use of an original dataset of qualitative interviews investigating homeownership pathways and the negotiations of support that they pre-suppose. The article explores the meanings and moral reasoning behind the decision to accept (or not) support in context of contemporary discourses surrounding the liquidity and availability of housing and finance. It highlights the moral compromises and emotional negotiations inherent in the giving and receiving of support for housing, contributing to a body of literature concerned with the reproduction of home and family. Furthermore, it stresses the importance of homes and housing assets in mediating dependence and re-affirming family bonds within a family-oriented welfare context, despite conflict, resistance and frustrated aspirations.
Report of Postdoctoral Visit to FernUniversität in Hagen Complex Networks: Topology, Dynamics and Synchronization

This report is a recompilation of the research done during my visit to FernUniversitat in Hagen from April 2005 to April 2006. It consists of a tutorial review of the background of Complex Dynamical Networks and some ideas set forward during this research period. The intension is for this manuscript to serve as a complement to the report for the DAAD Research Grant that I received to visit Germany and at the same time as a documental reference and background for future work. 1 Financially Supported by DAAD -Research Scholarship 2005-
Working from Home: Creativity and Innovation in the High-Tech Industry in Israel

Creativity is a crucial aspect of tech management, as it allows hi-tech workers to identify and solve problems, generate new ideas, and create innovative solutions that meet the needs and desires of consumers. The COVID-19 pandemic has had a significant impact on the way that people work, with many companies shifting to remote work as a means of maintaining business continuity. This shift has led to a debate about the impact of remote work on creativity, with some arguing that working from home increases creativity since it allows for more flexibility and autonomy. In contrast, others say it decreases it since it can lead to isolation and a lack of collaboration. While some evidence suggests that working from home may positively impact creativity, there is also evidence to suggest that it may have a negative impact. The main objective of this study is to investigate differences, if any, in the perceived creativity among hi-tech workers working from home or the office. The study provides a more nuanced understanding of hi-tech workers' attitudes toward creativity, innovation, and related risk-related issues. We used a validated questionary about the extent of innovation and creativity of people in general. Then we investigated these characteristics with the extent of working from home or the office. We statistically compared the means of variables of interest for categories of interest of respondents. We found no significant difference between high-tech workers working from home or the office. Yet, we discovered that hi-tech workers working from home reveal more resilience toward creative ways to solve problems even though these ways are associated with more risk. They are willing to take more risks to accomplish assignments innovatively and creatively. We also found that managers and development hi-tech workers tend to work from home.
As Time Goes By: Comprehensive Tagging of Textual Phrases with Temporal Scopes

Temporal expressions (TempEx's for short) are increasingly important in search, question answering, information extraction, and more. Techniques for identifying and normalizing explicit temporal expressions work well, but are not designed for and cannot cope with textual phrases that denote named events, such as "Clinton's term as secretary of state". This paper addresses the problem of detecting such temponyms, inferring their temporal scopes, and mapping them to events in a knowledge base if present there. We present methods for this kind of temponym resolution, using an entity- and TempEx-oriented document model and the Yago knowledge base for distant supervision. We develop a family of Integer Linear Programs for jointly inferring temponym mappings to the timeline and knowledge base. This enriches the document representation and also extends the knowledge base by obtaining new alias names for events. Experiments with three different corpora demonstrate the viability of our methods.
IMPROVING STUDENTS’ READING COMPREHENSION OF DESCRIPTIVE TEXTS THROUGH COGNITIVE STRATEGY AT GRADE VII-2 OF SMPN 1 INDRA PRAJA TEMBILAHAN MENINGKATKAN PEMAHAMAN MEMBACA DALAM TEKS DESKRIPTIF MELALUI COGNITIVE STRATEGY PADA SISWA KELAS VII-2 SMPN 1 INDRA PRAJA TEMBILAHAN

This study aims to determine whether cognitive strategy can improve students' skills in writing descriptive text, and what factors affect the improvement of writing skills. This research is a classroom action research conducted in two cycles. Each cycle consists of four meetings. Each consists of plan, action, observation, and reflection. Participants in this study is as straight as the students of class VII-2 SMPN 1 Indra Praja Tembilahan totaling 22 students. The data of this study were collected through: (1) observation sheet; students, teachers, teaching steps (2) field notes (3) interviews, and (4) writing tests. This study found that the use of cognitive strategy can improve students' skills in writing descriptive text. The findings of this study indicate that there is an increase in the average score of students above the completeness criteria of a minimum of English subjects is 75. The factors that influence the skills of students in writing descriptive text are (a) reading material given to the students, (b) motivation students, and (c) teacher's approach to students. So it can be concluded that the application of cognitive strategy on the teaching of reading descriptive text can give positive results with the increase of students' skills in reading descriptive text.
The architecture tradeoff analysis method

This paper presents the Architecture Tradeoff Analysis Method (ATAM), a structured technique for understanding the tradeoffs inherent in the architectures of software-intensive systems. This method was developed to provide a principled way to evaluate a software architecture's fitness with respect to multiple competing quality attributes: modifiability, security, performance, availability, and so forth. These attributes interact-improving one often comes at the price of worsening one or more of the others-as is shown in the paper, and the method helps us to reason about architectural decisions that affect quality attribute interactions. The ATAM is a spiral model of design: one of postulating candidate architectures followed by analysis and risk mitigation, leading to refined architectures.
Prevalence and Factors Associated with Atrial Fibrillation in Patients with Transient Ischemic Attack or Ischemic Stroke in Northern Vietnam

Background: The prevalence and risk factors of atrial fibrillation (AF) in patients with transient ischemic attack (TIA) or ischemic stroke in Northern Vietnam are not well understood. This study aimed to estimate the prevalence and identify factors associated with AF in this population. Methods: A cross-sectional study was conducted on 2038 consecutive patients with TIA or ischemic stroke admitted to Bach Mai Hospital. AF was diagnosed using an electrocardiogram or Holter monitor. Logistic regression analyses were performed to determine the association between AF and risk factors. Results: Among the patients, 18.1% (95% CI: 16.46 to 19.85) had AF. Older age, renal dysfunction, valvular heart disease (VHD), and low ejection fraction were significantly associated with AF. Advanced age (per 10 years) (adjusted OR, aOR 1.39; 95% CI, 1.23 to 1.57), estimated glomerular filtration ratio decrease (per 10 mL/min/1.73 m2) (aOR 1.12; 95% CI, 1.06 to 1.17), VHD (aOR 9.59; 95% CI, 7.10 to 12.95), and low ejection fraction (<50%) (aOR 2.61; 95% CI, 1.62 to 4.21) had notable odds ratios for AF. Conclusions: Atrial fibrillation is prevalent among patients with TIA or ischemic stroke in Northern Vietnam, surpassing rates in other Southeast Asian countries. Age, renal dysfunction, VHD, and low ejection fraction were significant risk factors for AF in this population.
Prevalence and factors associated with adolescent pregnancy among sexually active adolescent girls in Peru: Evidence from Demographic and Family Health Survey, 2015-2019

Background The objective of this study was to estimate the prevalence of adolescent pregnancy among sexually active adolescents, and identify the factors associated with this problem. Methods A population-based analytical cross-sectional study was conducted using pooled data from the Demographic and Family Health Surveys of Peru, 2015-2019. A total sample of 8850 adolescent girls aged 12 to 19 years who reported a history of sexual intercourse were included. To identify factors related to adolescent pregnancy, the study employed adjusted prevalence ratios (aPR) with 95% confidence intervals (95% CI). The aPR were obtained from a multivariable logistic regression model. Results The prevalence of adolescent pregnancy among sexually active adolescents in Peru was 30.9% (95%CI: 29.4–32.4%). In the multivariable analysis; being 17-19 years (aPR: 1.48; 95%CI:1.33–1.64), being married or cohabitant (aPR: 4.01; 95%CI: 3.48–4.61) and belonging to the Quechua ethnicity group (aPR: 1.16; 95%CI: 1.07–1.25), were associated with a higher prevalence. Conversely, the following factors were associated with a lower prevalence of pregnancy: being employed (aPR: 0.81; 95%CI: 0.76–0.86), being currently studying (aPR: 0.43; 95%CI: 0.38–0.49), belonging to the second (aPR: 0.91; 95%CI: 0.85–0.97), third (aPR: 0.81; 95%CI: 0.74–0.89), fourth (aPR: 0.79; 95%CI: 0.69–0.91) and fifth (aPR: 0.59; 95%CI: 0.47–0.75) wealth quintile, initiating sexual relations in middle adolescente (aPR: 0.76; 95%CI: 0.69–0.83) or late adolescence (aPR: 0.40; 95%CI: 0.35–0.46), perceiving a future pregnancy as a problem (aPR: 0.77; 95%CI: 0.72–0.83) and having knowledge of the moment in the cycle when pregnancy can occur (aPR: 0.84; 95%CI: 0.77–0.92) Conclusions Approximately three out of ten adolescents who initiated a sexual life had at least one pregnancy. Age, marital status, employment, education, wealth, ethnicity, age at first intercourse, knowledge of when in the cycle she may become pregnant, and perception of future pregnancy were associated with adolescent pregnancy. To decrease the prevalence of teenage pregnancy in Peru, it is imperative to enhance national policies concerning family planning and provide comprehensive sex education targeted at adolescents.
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