Miracle-dz/UniFAR-FTUs huggingface dataset:
Finding Common RNA Secondary Structures: A Case Study on the Dynamic Parallelization of a Data-driven Recurrence

This paper presents the dynamic parallelization of a sequential algorithm for finding common RNA secondary structures that initially does not appear to be amenable to parallelization. A critical insight into the problem structure, which at first appears to be inherently top-down, leads to the development of a revised sequential algorithm that uses both bottom-up tabulation and top-down memoization. This novel combined approach proves well-suited for parallelization, overcoming the inherent difficulties in parallelizing the original top-down algorithm. The improved algorithm also eliminates two factors from the space complexity to fit into quadratic space, enabling the comparison of lengthy and complex RNA structures. Experimental results demonstrate that the parallel algorithm scales well, achieving speedup of up to 32X using 64 processors for contrived worst-case data containing structures having up to 1600 nested arcs. This algorithm illustrates the significant benefits that can be achieved by designing an underlying sequential dynamic programming algorithm with parallelizability in mind, instead of directly parallelizing an existing sequential algorithm. Our results also show the usefulness of combining both bottom-up and top-down perspectives when designing a parallel dynamic programming algorithm.
Peer-to-peer caching schemes for integrated wired and wireless network environments

In order to make the unstructured P2P Freenet appropriate for integrated wired and wireless network environments, we propose two kinds of Freenet caching schemes, WDC (Wireless Dependent Caching) and HNS (Half Node Storing), and evaluate their performance through simulation. The performance of WDC is similar to the original Freenet, however it can save bandwidth of the wireless link significantly by replicating files only at wired nodes. With the HNS scheme, although it utilizes more bandwidth than WDC, nodes keep half of the files of the original Freenet, and both the number of hops for success and failure rate decrease. Therefore, the WDC scheme is appropriate for extremely limited wireless link or low proportion of wireless node environments while the HNS scheme can provide a smaller number of hops to success and higher success rate than the original Freenet
Systematic review of the effect of smoking on nonsurgical periodontal therapy.

abstraction, quality assessment, and data analysis.This aspect of the design was planned to minimizethe effect of our possible bias on the review and, inparticular, on the potential to alter the methods oranalytical techniques based on study ﬁndings. Search strategy The search strategy involved the use of the followingelectronic databases: MEDLINE, EMBASE and theCochrane Central Register of Controlled ClinicalTrials (CENTRAL), as well as hand searching of bib-liographies of found references, review articles andconsensus statements. All databases were searchedfrom their earliest records until March 2003; onlyEnglish language publications were searched. The fullsearch strategy is included as Appendix 1. Study selection The primary study design selected was controlledclinical trials as smoking habit cannot be random-ized. In addition, arms of randomized controlled tri-als investigating the effectiveness of nonsurgicalperiodontal treatment that reported results sepa-rately for smokers and nonsmokers were included.Other inclusion criteria were studies that assessedsystemically healthy patients who had been diag-nosed with chronic or adult periodontitis and wherethe patient was the unit of analysis (rather than atooth- or site-based analysis). Studies were notexcluded on the basis of quality, only on whetherthey fulﬁlled the inclusion criteria for entry. Weplanned to investigate the impact of quality on studyoutcome if there was heterogeneity between studies.
TFC selection for MAC scheduling in WCDMA

Reacting to the evolution of user's needs toward multimedia applications, an important feature of the third generation mobile networks is to support efficiently multiple applications with different quality of service. In the radio access networks of UMTS, RLC/MAC layers are designed to accommodate simultaneously mixed services through establishing multiple bearers. A major issue is the rate adaption of these bearers. In this paper, we examine the scheduling problem in the WCDMA MAC layer and propose five scheduling methods. Our simulation result shows that a load measurement based priority method can achieve better fairness and has better execution time performance than the other four methods.
Gene-Based Therapy for Hypertension – Do Preclinical Data Suggest a Promising Future?

Many experimental studies have obtained a prolonged control of blood pressure through gene treatment. This consists in the administration of genes coding for vasodilator proteins (the ‘sense’ approach), or of nucleotide sequences that are complementary to the mRNA of vasoconstrictor proteins, which are consequently synthesized in smaller amounts (the ‘antisense’ approach). Examples of the sense approach include the genes encoding endothelial nitric oxide synthase and kallikrein. Examples of the second type of approach are the antisense oligodeoxynucleotides to angiotensin-converting enzyme and endothelin-1. Also, RNA molecules, such as ribozymes and small interfering RNAs, are capable to inhibit RNA function. Whole sense genes are usually administered through viral vectors, while antisense oligonucleotides may be administered with plasmids or liposomes. Both viral and non-viral vectors have advantages and disadvantages. Despite the still persisting limitations, the possibility exists that in the future some forms of genetic treatment will be extended to the clinical setting, allowing a prolonged control of essential hypertension and its end-organ sequelae.
Ground Granulated Blast Slag (GGBS) In Concrete – A Review

Concrete is a mixture of cement, fine aggregate, coarse aggregate and water. Concrete plays a vital role in the development of infrastructure Viz., buildings, industrial structures, bridges and highways etc. leading to utilization of large quantity of concrete. On the other side, cost of concrete is attributed to the cost of its ingredients which is scarce and expensive, this leading to usage of economically alternative materials in its production. This requirement is drawn the attention of investigators to explore new replacements of ingredients of concrete. The present technical report focuses on investigating characteristics of concrete with partial replacement of cement with Ground Granulated Blast furnace Slag (GGBS). The topic deals with the usage of GGBS and advantages as well as disadvantages in using it in concrete. This usage of GGBS serves as replacement to already depleting conventional building materials and the recent years and also as being a by product it serves as an Eco Friendly way of utilizing the product without dumping it on ground.
Development of high resolution scanning aeoustie tomograph for advanced LSI packages

We have newly developed a scanning acoustic tomograph with higher resolution and detectability than the conventional type. The system can be equipped with a special signal processing unit that has been designed in order to emphasize the high frequency component of ultrasound. The signal processing unit enhanced the resolution and signal to noise ratio. Because of improvement in the signal to noise ratio, a slit with a width of 1 μm was detected by the new system with the signal processing unit.
Predictors of Stress Fracture Susceptibility in Young Female Recruits

Background Stress fractures account for substantial morbidity for young women undergoing U.S. Marine Corps basic training. Hypothesis Certain pretraining characteristics identify women at increased risk of stress fractures during boot camp. Study Design Cohort study; Level of evidence, 2. Methods Data collected included baseline performance on a timed run (a measure of aerobic fitness), anthropometric measurements, and a baseline questionnaire highlighting exercise and menstrual status among 2962 women undergoing basic training at the Marine Corps Recruit Depot, Parris Island, in 1995 and 1996. Results One hundred fifty-two recruits (5.1%) had 181 confirmed lower extremity stress fractures, with the most common sites being the tibia (25%), metatarsals (22%), pelvis (22%), and femur (20%). Logistic regression models revealed that having low aerobic fitness (a slower time on the timed run) and no menses during the past year were significantly associated with the occurrence of any stress fracture and with pelvic or femoral stress fracture during boot camp. Conclusion These findings suggest that stress fractures may be reduced if women entering Marine Corps Recruit Depot training participated in pretraining activities designed to improve aerobic fitness. Furthermore, women reporting no menses during the previous year may need additional observation during training. Clinical Relevance Consistent with previous studies, we found that low aerobic fitness was the only modifiable risk factor associated with stress fractures during boot camp.
Effects of Model Complexity on Generalization Performance of Convolutional Neural Networks

Convolutional neural networks are known to be effective in learning complex image classification tasks. However, how to design the architecture or complexity of the network structure requires a more quantitative analysis of the architecture design. In this paper, we study the effect of model complexity on generalization capability of the convolutional neural networks on large-scale, real-life digit recognition data. We used the digit images of the MNIST dataset to train the neural networks and evaluated their performance on a test set of unobserved images. Using the LeNet software tool we varied the number of hidden layers and the number of units in the layers to evaluate the effect of model complexity on the generalization capability of the convolutional neural networks. In our experimental settings, we observe robust generalization performances of the convolutional neural networks on a wide range of model complexities. We analyze and discuss how the convolution layer and the subsampling layer may contribute to the generalization performance.
Three‐Plane Ballistocardiography: The Effect of Age on the Longitudinal, Lateral, and Dorsoventral Ballistocardiograms

The motions of the thorax and of the shins were recorded by a technic which gives approximately the same size waves when a given force is applied to the thorax in each of three planes. Applied to a group of men and women under 30 years of age and another group of normals over 50, the variations in form and size of the ballistocardiographic forces in three planes were recorded. During expiration and as a result of aging, the lateral systolic wave, IJ, increases in size relative to the head-foot IJ. It is concluded that the classic head-foot ballistocardiogram yields inadequate information on the force liberated in systole, particularly in older men.
Electrotravelgram: Data art & DIY sensors

This paper intends to discuss some of the theories on data visualization and their application to the arts. As an example of mapping art, I plan to analyze an artwork we have developed at Ecoarte group that presents a control panel of the data collected during the 2-day trip on the sea and river. As part of the “Sensorium: from the sea to the river” project, “Electrotravelgram” presents the data collected by different sensors as a way to tell a story of this journey. The eight measurements of the environment captured by these sensors are here presented visually in order to produce a new form of perceiving the space.
A cultural model of infidelity among African American and Puerto Rican young adults

Having concurrent sexual partners is a risk factor for STIs and HIV/AIDS, yet few studies have investigated the cultural meanings and functions of concurrency. A multi-method qualitative/quantitative study of sexual ideas, attitudes, and behaviors among inner-city Puerto Rican and African American emergent adults (age 18–25) in Hartford, Connecticut, USA, suggests that having concurrent partners is common in this population. Using data from 12 focus groups and 40 participants in systematic data collection techniques (e.g., pile sorts), the underlying cognitive structure of concurrency and cheating/infidelity are explored. Results suggest that participants are less tolerant of multiple partners in more committed relationships, but that very few relationships can be considered committed. Furthermore, participants see cheating as inevitable even in committed relationships. Sexual transgressions are considered the most severe form of cheating. Having an outside partner for emotional reasons or to have access to one's child were seen as more acceptable/forgivable than doing so for sexual satisfaction, social status or material goods. Multiple partnerships must be seen in the context of the inner city where resources and opportunities are scarce and young adults attempt to protect themselves from emotional injury. Documenting new and changing social constructions of infidelity is important for understanding the social context of sexual behavior in our global world and for designing culturally appropriate health interventions.
Intracellular neutralization of viral infection in polarized epithelial cells by neonatal Fc receptor (FcRn)-mediated IgG transport

IgG was traditionally thought to neutralize virions by blocking their attachment to or penetration into mucosal epithelial cells, a common site of exposure to viruses. However, we describe an intracellular neutralizing action for an influenza hemagglutinin-specific monoclonal antibody, Y8-10C2 (Y8), which has neutralizing activity only at an acidic pH. When Y8 was applied to the basolateral surface of Madin–Darby canine kidney cells expressing the rat neonatal Fc receptor for IgG (FcRn), it significantly reduced viral replication following apical exposure of the cell monolayer to influenza virus. Virus neutralization by Y8 mAb was dependent on FcRn expression and its transport of IgG. As both FcRn and Y8 mAb bind their partners only at acidic pH, the Y8 mAb is proposed to carry out its antiviral activity intracellularly. Furthermore, the virus, Y8 mAb, and FcRn colocalized within endosomes, possibly inhibiting the fusion of viral envelopes with endosomal membranes during primary uncoating, and preventing the accumulation of the neutralized viral nucleoprotein antigen in the nucleus. Prophylactic administration of Y8 mAb before viral challenge in WT mice, but not FcRn-KO mice, conferred protection from lethality, prevented weight loss, resulted in a significant reduction in pulmonary virus titers, and largely reduced virus-induced lung pathology. Thus, this study reveals an intracellular mechanism for viral neutralization in polarized epithelial cells that is dependent on FcRn-mediated transport of neutralizing IgG.
FGA effects on plasma-induced damage: beyond the appearances

Indispensable for manufacturing of modern CMOS technologies, plasma processes result in charging of dielectric surfaces, thus damaging the gate oxide. A forming gas annealing (FGA) step is usually done at the end of the process to passivate and/or recover this damage. We investigated this problem on thin (3.5 nm) gate oxides by using a series of stress-anneal-stress steps on devices with different level of latent damage. Our results confirm that FGA actually reduces the number of traps responsible for stress-induced leakage current (SILC) or for microbreakdown in ultrathin gate oxides, but also put in evidence that defects induced by plasma treatments and those generated by way of electrical stress feature different anneal kinetics. Further, we have identified two categories of dielectric breakdown events, whose characteristics are strongly modified by the FGA step.
Plastic-Compatible Low Resistance Printable Gold Nanoparticle Conductors for Flexible Electronics

Low resistance conductors are crucial for the development of ultra-low-cost electronic systems such as radio frequency identification tags. Low resistance conductors are required to enable the fabrication of high- Q inductors, capacitors, tuned circuits, and interconnects. The fabrication of these circuits by printing will enable a dramatic reduction in cost, through the elimination of lithography, vacuum processing, and the need for high-cost substrates. Solutions of organic-encapsulated gold nanoparticles many be printed and subsequently annealed to form low resistance conductor patterns. We describe a process to form the same, and discuss the optimization of the process to demonstrate plastic-compatible gold conductors for the first time. By optimizing both the size of the nanoparticle and the length of the alkanethiol encapsulant, it is possible to produce particles that anneal at low temperatures (,150°C) to form continuous gold films having low resistivity. We demonstrate the printing of these materials using
Designing Crushers With A Multi-objective Evolutionary Algorithm

This paper describes the use of a multi-objective evolutionary algorithm to solve an engineering design problem - determining the geometry and operating settings for a crusher in a comminution circuit for ore processing. The outcome is a tool for consulting engineers that can be used to create and explore candidate designs for various scenarios. The tool has proved capable of deriving designs that are clearly superior to existing designs, promising significant financial benefits. The approach is flexible enough to be applied to a variety of similar problems.
Analyzing Mapping Extraction Approaches

While lots of research in ontology matching is related to the issue of computing and refining similarity measures, only little attention has been paid to question how to extract the final alignment from a matrix of similarity values. In this paper we present a theoretical framework for describing extraction methods and argue that the quality of the final matching result is highly affected by the extraction method. Therefore, we discuss several extraction methods and apply them to some of the results submitted to the OAEI 2006. The results of our experimental study show that the proposed strategies differ with respect to precision and recall. In particular, theoretical considerations as well as emprirical results indicate that methods that additionally make use of information encoded in the ontologies result in better extractions compared to state of the art approaches.
Tweet if you will: the real question is, who do you influence?

Large numbers of today's businesses use social media in advertising. There is a belief in a great opportunity, even if return on investment is difficult to quantify. To fill this gap we consider a cross-media-platform-analysis across Facebook, Twitter and Foursquare. Rationale for and against different characteristics within social media advertisement are addressed. The paper finds correlation from posts and tweets to Foursquare check-ins. Results show that posts or tweets containing pictures have higher return on investment than posts or tweets without, and that when the text of a post or tweet raises curiosity or attracts individuals or groups Foursquare check-ins increase.
Syntactic and semantic validation of SPARQL queries

In this paper we present a tool to syntactically and semantically validate SPARQL queries. With this aim, we extract triple patterns and filter conditions from SPARQL queries and we use the OWL API and an OWL ontology reasoner in order to detect wrong expressions. Given an ontology and a query, the tool reports different kinds of programming errors: wrong use of vocabulary, wrong use of resources and literals, wrong filter conditions and wrong use of variables in triple patterns and filter conditions. When the OWL ontology reasoner is used the tool reports a diagnosis.
Transcriptional regulation by MAP kinases

Tyrosine kinase growth factor receptors activate MAP kinase by a complex mechanism involving the SH2/3 protein Grb2, the exchange protein Sos, and Ras. The GTP‐bound Ras protein binds to the Raf kinase and initiates a protein kinase cascade that leads to MAP kinase activation. Three MAP kinase kinase kinases have been described‐c‐Raf, c‐Mos, and Mekk—that phosphorylate and activate Mek, the MAP kinase kinase. Activated Mek phosphorylates and activates MAP kinase. Subsequently, the activated MAP kinase translocates into the nucleus where many of the physiological targets of the MAP kinase signal transduction pathway are located. These substrates include transcription factors that are regulated by MAP kinase phosphorylation (e.g., Elk‐1, c‐Myc, c‐Jun, c‐Fos, and C/EBPβ). Thus the MAP kinase pathway represents a significant mechanism of signal transduction by growth factor receptors from the cell surface to the nucleus that results in the regulation of gene expression.
The rise of the (modelling) bots: Towards assisted modelling via social networks

We are witnessing a rising role of mobile computing and social networks to perform all sorts of tasks. This way, social networks like Twitter or Telegram are used for leisure, and they frequently serve as a discussion media for work-related activities. In this paper, we propose taking advantage of social networks to enable the collaborative creation of models by groups of users. The process is assisted by modelling bots that orchestrate the collaboration and interpret the users' inputs (in natural language) to incrementally build a (meta-)model. The advantages of this modelling approach include ubiquity of use, automation, assistance, natural user interaction, traceability of design decisions, possibility to incorporate coordination protocols, and seamless integration with the user's normal daily usage of social networks. We present a prototype implementation called SOCIO, able to work over several social networks like Twitter and Telegram, and a preliminary evaluation showing promising results.
Increasing the tracking region of an eye-in-hand system using controlled active vision

A control strategy that allows a manipulator-camera system to track objects with planar motion while simultaneously avoiding kinematic singularities by moving in directions along which the tracking task space is unconstrained is presented. The projection of a Cartesian manipulability gradient on these directions of motion is used to determine the magnitude and direction of the required motion for singularity avoidance, while the controlled active vision paradigm is used for tracking. The algorithms developed have been experimentally verified on an eye-in-hand system. Results demonstrate the effectiveness of the method by showing that the tracking region of a manipulator tracking objects with planar motion can be increased by a factor of between two and three. The overall accuracy of the tracking system is also improved. <<ETX>>