Miracle-dz/UniFAR-FTUs huggingface dataset:
A study on the structure of information platform for virtual logistics based on agent

Virtual logistics is a modern logistics mode in which logistics efficiency can be enhanced and logistics resources can be saved greatly, while as logistics information platform is the technical base for it. This paper studies the structure of virtual logistics information platform based on Multi-Agent. It first argues the whole framework of virtual logistics information platform is mainly constructed by customer management module, task scheduling module, business processing module, resource integrating module and process monitoring module. Then Agent elements and their relative functions, running principles in the main modules are analyzed.
Neurogenesis may relate to some but not all types of hippocampal‐dependent learning

The hippocampal formation generates new neurons throughout adulthood. Recent studies indicate that these cells possess the morphology and physiological properties of more established neurons. However, the function of adult generated neurons is still a matter of debate. We previously demonstrated that certain forms of associative learning can enhance the survival of new neurons and a reduction in neurogenesis coincides with impaired learning of the hippocampal‐dependent task of trace eyeblink conditioning. Using the toxin methylazoxymethanol acetate (MAM) for proliferating cells, we tested whether reduction of neurogenesis affected learning and performance associated with different hippocampal dependent tasks: spatial navigation learning in a Morris water maze, fear responses to context and an explicit cue after training with a trace fear paradigm. We also examined exploratory behavior in an elevated plus maze. Rats were injected with MAM (7 mg/kg) or saline for 14 days, concurrent with BrdU, to label new neurons on days 10, 12, and 14. After treatment, groups of rats were tested in the various tasks. A significant reduction in new neurons in the adult hippocampus was associated with impaired performance in some tasks, but not with others. Specifically, treatment with the antimitotic agent reduced the amount of fear acquired after exposure to a trace fear conditioning paradigm but did not affect contextual fear conditioning or spatial navigation learning in the Morris water maze. Nor did MAM treatment affect exploration in the elevated plus maze. These results combined with previous ones suggest that neurogenesis may be associated with the formation of some but not all types of hippocampal‐dependent memories. Hippocampus 2002;12:578–584. © 2002 Wiley‐Liss, Inc.
The importance of quantum decoherence in brain processes

Based on a calculation of neural decoherence rates, we argue that that the degrees of freedom of the human brain that relate to cognitive processes should be thought of as a classical rather than quantum system, i.e., that there is nothing fundamentally wrong with the current classical approach to neural network simulations. We find that the decoherence timescales ~10^{-13}-10^{-20} seconds are typically much shorter than the relevant dynamical timescales (~0.001-0.1 seconds), both for regular neuron firing and for kink-like polarization excitations in microtubules. This conclusion disagrees with suggestions by Penrose and others that the brain acts as a quantum computer, and that quantum coherence is related to consciousness in a fundamental way.
Complex Dynamics in Ecological Time Series

Although the possibility of complex dynamical behaviors-limit cycles, quasiperiodic oscillations, and aperiodic chaos-has been recognized theoretically, most ecologists are skeptical of their importance in nature. In this paper we develop a meth- odology for reconstructing endogenous (or deterministic) dynamics from ecological time series. Our method consists of fitting a response surface to the yearly population change as a function of lagged population densities. Using the version of the model that includes two lags, we fitted time-series data for 14 insect and 22 vertebrate populations. The 14 insect populations were classified as: unregulated (1 case), exponentially stable (three cases), damped oscillations (six cases), limit cycles (one case), quasiperiodic oscillations (two cases), and chaos (one case). The vertebrate examples exhibited a similar spectrum of dynamics, although there were no cases of chaos. We tested the results of the response-surface meth- odology by calculating autocorrelation functions for each time series. Autocorrelation pat- terns were in agreement with our findings of periodic behaviors (damped oscillations, limit cycles, and quasiperiodicity). On the basis of these results, we conclude that the complete spectrum of dynamical behaviors, ranging from exponential stability to chaos, is likely to be found among natural populations.
Vodcasts and Active-Learning Exercises in a “Flipped Classroom” Model of a Renal Pharmacotherapy Module

Objective. To implement a “flipped classroom” model for a renal pharmacotherapy topic module and assess the impact on pharmacy students’ performance and attitudes. Design. Students viewed vodcasts (video podcasts) of lectures prior to the scheduled class and then discussed interactive cases of patients with end-stage renal disease in class. A process-oriented guided inquiry learning (POGIL) activity was developed and implemented that complemented, summarized, and allowed for application of the material contained in the previously viewed lectures. Assessment. Students’ performance on the final examination significantly improved compared to performance of students the previous year who completed the same module in a traditional classroom setting. Students’ opinions of the POGIL activity and the flipped classroom instructional model were mostly positive. Conclusion. Implementing a flipped classroom model to teach a renal pharmacotherapy module resulted in improved student performance and favorable student perceptions about the instructional approach. Some of the factors that may have contributed to students’ improved scores included: student mediated contact with the course material prior to classes, benchmark and formative assessments administered during the module, and the interactive class activities.
ROBUST PERFORMANCE IN BIOPHYSICAL NETWORKS

Abstract Robust performance, the attainment of a specified response under uncertainty, is a well studied problem in control engineering. In the field of systems biology, related problems are emerging from the quantitative analysis of complex biophysical networks. In this paper, connections are made between the robust performance questions in biology and engineering. Two examples are used to illustrate these ideas: (i) a signal transduction network, and (ii) the gene network responsible for circadian oscillations.
A Conserved Threonine Residue in the Juxtamembrane Domain of the XA21 Pattern Recognition Receptor Is Critical for Kinase Autophosphorylation and XA21-mediated Immunity*

Despite the key role that pattern recognition receptors (PRRs) play in regulating immunity in plants and animals, the mechanism of activation of the associated non-arginine-aspartate (non-RD) kinases is unknown. The rice PRR XA21 recognizes the pathogen-associated molecular pattern, Ax21 (activator of XA21-mediated immunity). Here we show that the XA21 juxtamembrane (JM) domain is required for kinase autophosphorylation. Threonine 705 in the XA21 JM domain is essential for XA21 autophosphorylation in vitro and XA21-mediated innate immunity in vivo. The replacement of Thr705 by an alanine or glutamic acid abolishes XA21 autophosphorylation and eliminates interactions between XA21 and four XA21-binding proteins in yeast and rice. Although threonine residues analogous to Thr705 of XA21 are present in the JM domains of most RD and non-RD plant receptor-like kinases, this residue is not required for autophosphorylation of the Arabidopsis RD RLK BRI1 (brassinosteroid insensitive 1). The threonine 705 of XA21 is conserved only in the JM domains of plant RLKs but not in those of fly, human, or mouse suggesting distinct regulatory mechanisms. These results contribute to growing knowledge regarding the mechanism by which non-RD RLKs function in plant.
Climate-Based Model Predicting Acarological Risk of Encountering the Human-Biting Adult Life Stage of Dermacentor andersoni (Acari: Ixodidae) in a Key Habitat Type in Colorado

Abstract We exploited an elevation (climate) gradient ranging from 1,700 to 2,500 m in Poudre Canyon of Larimer County, CO, to determine climatic correlates of abundance per 15-s drag sampling time unit (hereafter referred to as abundance) of the human-biting adult life stage of the Rocky Mountain wood tick, Dermacentor andersoni Stiles (Acari: Ixodidae), in a key risk habitat for tick exposure: south/west-facing, rocky hillsides with mixed grass–brush–conifer vegetation. The relationship between elevation and abundance was parabolic, with peak tick abundances occurring at mid-range elevations (2,200–2,400 m) and tick abundances approaching zero at ≈2,100 and 2,500 m. Regression modeling demonstrated that abundance of host-seeking adult ticks in south/west-facing exposures was accurately predicted by several climate variables related to temperature (e.g., mean annual minimum temperature, maximum temperature, and base 10°C growing degree-days, and median length of annual freeze-free period; r2 values ranging from 0.771 to 0.864), whereas mean annual precipitation, snowfall, or relative humidity were uninformative in this respect (r2 values ranging from 0.020 to 0.316). Abundance of D. andersoni adults peaked at a mean annual maximum temperature of ≈10°C and a mean annual growing degree-day value of ≈650. Relationships between climate variables and abundance of D. andersoni adults were used to create geographic information system (GIS)-based models for predicted tick abundance in south/west-facing exposures in Larimer County. This is the first GIS-based model developed for spatial patterns of abundance of D. andersoni. Finally, preliminary data from Poudre Canyon indicate a shift toward peak abundances of D. andersoni adults occurring in sheltered northern/eastern exposures, rather than in drier and hotter southern/western exposures, at elevations below 2,100 m.
Clusters as vehicles for entrepreneurial innovation and new idea generation - a critical assessment

Recent theorizing in cluster literature emphasizes the importance of inter-cluster knowledge linkages in addition to local knowledge dynamics, enabling new and innovative ideas to flow from one cluster to the other. This paper contributes to this topic by studying inter-cluster knowledge linkages at an individual level of analysis, making use of qualitative social network measures. Central to this case is the Amsterdam New Media-cluster, with a special focus on entrepreneurs engaging in lively inter-cluster exchange of knowledge and debate, resulting in the exchange of new visions and ideas across cluster boundaries. The results reported in this paper provide us with an opportunity to discuss cluster boundaries as a social construction, especially in relation to the knowledge-based view of clusters.
Privacy and Information Markets: Controlling Information Flows in Decentralized Social Networking

The contribution motivates a substantial conceptual overlap between privacy control and potential information markets in decentralized contextual Social Networking and suggests substituting appropriate means for controlling outgoing and incoming information flows as the key problem of both points of view. An XACML-based approach for information flow control is suggested based on social conventions and involving traceable signed speech acts and sticky policies based on long- and short term social contexts, spatio-temporal regions and digital IDs as basic building blocks. An analysis of the basic micro-economics of information markets based on such a flow control approach shows how price building mechanisms and other characteristics of these markets may contribute to privacy and information quality.
1. Lexicalized meaning and the internal temporal structure of events

This paper addresses the question of whether the four-way Vendler classification is appropriate for verbs or VPs. It suggests that the Vendler classification is not appropriate as a classification of verbs, and offers a different classification for the elements of lexicalized meaning which determine the aspectual potential of verbs. It highlights the importance of a class of verbs with a lexically encoded scale, illustrating that a large class of scalar verbs cannot be classified once and for all either as activities, accomplishments or achievements, though the lexically encoded scale accounts for most of the aspectual behavior of these verbs. The aspectual and syntactic significance of a lexicalized scale is explored. The class of verbs lexicalizing a scale is shown not to be the same as the class of verbs selecting an incremental theme. This is justified both on semantic grounds and on syntactic grounds. There appears to be more justification for recognizing the four-way Vendler classification at the VP level, though it is demonstrated that accomplishments do not have a uniform internal temporal structure, predominantly because of the variety of sources of incremental structure.
Regulatory mutations in Sin recombinase support a structure-based model of the synaptosome

The resolvase Sin regulates DNA strand exchange by assembling an elaborate interwound synaptosome containing catalytic and regulatory Sin tetramers, and an architectural DNA‐bending protein. The crystal structure of the regulatory tetramer was recently solved, providing new insights into the structural basis for regulation. Here we describe the selection and characterization of two classes of Sin mutations that, respectively, bypass or disrupt the functions of the regulatory tetramer. Activating mutations, which allow the catalytic tetramer to assemble and function independently at site I (the crossover site), were found at ∼20% of residues in the N‐terminal domain. The most strongly activating mutation (Q115R) stabilized a catalytically active synaptic tetramer in vitro. The positions of these mutations suggest that they act by destabilizing the conformation of the ground‐state site I‐bound dimers, or by stabilizing the altered conformation of the active catalytic tetramer. Mutations that block activation by the regulatory tetramer mapped to just two residues, F52 and R54, supporting a functional role for a previously reported crystallographic dimer–dimer interface. We suggest how F52/R54 contacts between regulatory and catalytic subunits might promote assembly of the active catalytic tetramer within the synaptosome.
Multimedia analysis of video sources

Law Enforcement Agencies (LEAs) spend increasing efforts and resources on monitoring open sources, searching for suspicious behaviours and crime clues. The task of efficiently and effectively monitoring open sources is strongly linked to the capability of automatically retrieving and analyzing multimedia data. This paper presents a multimodal analytics system, created in cooperation with European LEAs. In particular it is described how the video analytics subsystem produces a workflow of multimedia data analysis processes. After a first analysis of video files, images are extracted in order to perform image comparison, classification and face recognition. In addition, audio content is extracted to perform speaker recognition and multilingual analysis of text transcripts. The integration of multimedia analysis results allows LEAs to extract pertinent knowledge from the gathered information.
A High-Level Implementation of STM Haskell with Write/Write Conflict Detection

This paper describes a high level implementation of Software Transactional Memory (STM) for the Haskell language. The library is implemented completely in Haskell and, as opposed to all other implementation of STM Haskell, it features early detection of write/write conflicts. Preliminary performance measurements using the Haskell STM benchmark show that the library performs much better than a TL2~implementation written in Haskell, and performs reasonably well compared to the current implementation of STM Haskell written in C.
Hand interception of occluded motion in humans : A test of model-based versus on-line control 2 3

3 Barbara La Scaleia, Myrka Zago and Francesco Lacquaniti 4 Laboratory of Neuromotor Physiology, IRCCS Santa Lucia Foundation, Via Ardeatina 306, 00179 5 Rome, Italy, Italy, Department of Systems Medicine, University of Rome Tor Vergata, Via 6 Montpellier 1, 00133 Rome, Centre of Space Bio-medicine, University of Rome Tor Vergata, Via 7 Montpellier 1, 00133 Rome, Italy 8 9 Authors’ contributions: B.LS. , M.Z. and F.L. designed the experiments, B.LS. performed the 10 experiments and analyzed the data, M.Z. contributed methodology, B.LS. , M.Z. and F.L. wrote the 11 manuscript. All authors read and approved the submitted manuscript. 12 13 Running head: Hand interception of occluded projectile motion 14 15 Correspondence: 16 Dr. Barbara La Scaleia 17 IRCCS Fondazione Santa Lucia 18 via Ardeatina 306 19 00179 Rome (Italy) 20 b.lascaleia@hsantalucia.it 21 22 23 Articles in PresS. J Neurophysiol (July 1, 2015). doi:10.1152/jn.00475. 2015
Sphingosine Kinase 2 Is Required for Modulation of Lymphocyte Traffic by FTY720*

Immunotherapeutic drugs that mimic sphingosine 1-phosphate (S1P) disrupt lymphocyte trafficking and cause T helper and T effector cells to be retained in secondary lymphoid tissue and away from sites of inflammation. The prototypical therapeutic agent, 2-alkyl-2-amino-1,3-propanediol (FTY720), stimulates S1P signaling pathways only after it is phosphorylated by one or more unknown kinases. We generated sphingosine kinase 2 (SPHK2) null mice to demonstrate that this kinase is responsible for FTY720 phosphorylation and thereby its subsequent actions on the immune system. Both systemic and lymphocyte-localized sources of SPHK2 contributed to FTY720 induced lymphopenia. Although FTY720 was selectively activated in vivo by SPHK2, other S1P pro-drugs can be phosphorylated to cause lymphopenia through the action of additional sphingosine kinases. Our results emphasize the importance of SPHK2 expression in both lymphocytes and other tissues for immune modulation and drug metabolism.
Removing Shadows for Color Projection Using Sun Position Estimation

The result of an outdoors 3D scanning acquisition campaign is usually an accurate 3D model of the site, but in most of the cases the quality of the color acquired by the scanner is not satisfying. Alternative solutions, like the projection of a photographic dataset acquired in a different stage, are still dependent on the quality of the initial images. The short time for the acquisition campaigns and the weather conditions often force the shooting of images taken under a strong direct sun illumination. This generates colored models of poor quality. In this paper we present a method to estimate the sun position starting from a geo-referenced 3D model and a set of images. The sun position can enhance both the image alignment and color projection phases. Moreover, the detection and removal of the shadows from the images produces a better and more coherent color in the final 3D model. Using this kind of approach, outdoor sites can be acquired producing a high quality color information together with an accurate geometric measurement.
Digit Recognition in Handwritten Weather Records

Abstract. This paper addresses the automatic recognition of handwritten tem-peraturevaluesinweatherrecords. Thelocalizationoftablecellsisbasedon line detection using projection proﬁles. Further, a stroke-preservinglineremovalmethodwhichisbasedongradientimagesisproposed. Thepresented digit recognition utilizes features which are extracted using aset of ﬁlters and a Support Vector Machine classiﬁer. It was evaluatedontheMNISTandtheUSPSdatasetandourowndatabasewithabout17,000RGBdigitimages. Anaccuracyof99.36%perdigitisachievedfortheentiresystemusingasetof84weatherrecords. 1 Introduction Inadditiontohandwrittendocumentsstoredinhistoricarchivestherearepro-cesses, like manually ﬁlling out forms, which still depend on pen and paper.However, accessing the information stored in those documents requires timeand manpower [9]. By digitizing those documents, the advantages of digitallystored information, such as ease of access, can be exploited for handwrittendocuments[9]. Thedocumentscoveredinthispaper,i.e. weatherrecords,consistofknownprintedformswithhandwritteninformation. Eventhoughthestructureoftheform is known beforehand, due to prior handling and the scanning process,global and local deformations are introduced. Further, the structure of formssuggestscertainareaswhichareapplicableforhandwriting,yetwritersarenotbound to this constraint. Additionally, handwriting varies signiﬁcantly dueto diﬀerent writing styles. Even the handwriting of a single writer exhibitsvariations. In Figure 1 an example of a weather record is shown. The originsoftheweatherrecordsregardedinthispaperareseveralmeasurementstationslocatedinAustria(LowerAustria). Figure1: WeatherrecordfromFebruaryoftheyear2000fromameasurementstation in Lower Austria. The temperature values are located in the column"Lufttemperatur
Combining Text and Formula Queries in Math Information Retrieval: Evaluation of Query Results Merging Strategies

Specific to Math Information Retrieval is combining text with mathematical formulae both in documents and in queries. Rigorous evaluation of query expansion and merging strategies combining math and standard textual keyword terms in a query are given. It is shown that techniques similar to those known from textual query processing may be applied in math information retrieval as well, and lead to a cutting edge performance. Striping and merging partial results from subqueries is one technique that improves results measured by information retrieval evaluation metrics like Bpref.
Fast ICP-SLAM for a bi-steerable mobile robot in large environments

This paper describes the implementation of a local ICP-SLAM (Iterative Closest Point - Simultaneous Localization and Mapping) to improve the method presented in [1] to become faster. The ICP algorithm is known as a method that requires more computation time when the environment grows leading to poor results for both localization and mapping. Therefore, the ICP-SLAM is not recommended to use in real time for large environments. To overcome this problem, a local ICP-SLAM is introduced which is based on the partition of the environment on smaller parts. This method is implemented and tested on the car-like mobile robot “Robucar”. It allows the optimization of the computation time and localization accuracy. The experimental results show the effectiveness of the proposed local ICP-SLAM compared to the method in [1].