Miracle-dz/UniFAR-FTUs huggingface dataset:
Functional Analysis of Conserved Motifs in the Mechanosensitive Channel Homolog MscS-Like2 from Arabidopsis thaliana

The Mechanosensitive channel of Small conductance (MscS) of Escherichia coli has become an excellent model system for the structural, biophysical, and functional study of mechanosensitive ion channels. MscS, a complex channel with multiple states, contributes to protection against lysis upon osmotic downshock. MscS homologs are widely and abundantly dispersed among the bacterial and plant lineages, but are not found in animals. Investigation into the eukaryotic branch of the MscS family is in the beginning stages, and it remains unclear how much MscS homologs from eukaryotes resemble E. coli MscS with respect to structure, function, and regulation. Here we test the effect of mutating three conserved motifs on the function of MscS-Like (MSL)2, a MscS homolog localized to the plastids of Arabidopsis thaliana. We show that 1) a motif at the top of the cytoplasmic domain, referred to here as the PN(X)9N motif, is essential for MSL2 function and for its proper intraplastidic localization; 2) substituting polar residues for two large hydrophobic residues located in the predicted pore-lining transmembrane helix of MSL2 produces a likely gain-of-function allele, as previously shown for MscS; and 3) mis-expression of this allele causes severe defects in leaf growth, loss of chloroplast integrity, and abnormal starch accumulation. Thus, two of the three conserved motifs we analyzed are critical for MSL2 function, consistent with the conservation of structure and function between MscS family members in bacteria and plants. These results underscore the importance of plastidic mechanosensitive channels in the maintenance of normal plastid and leaf morphology.
BUTknot at SemEval-2016 Task 5: Supervised Machine Learning with Term Substitution Approach in Aspect Category Detection

This paper describes an approach used to solve Aspect Category Detection (Subtask 1, Slot 1) of SemEval 2016 Task 5. The core of the presented system is based on Supervised machine learning using bigram bag-of-words model. The performance is enhanced by several pre-processing methods, most importantly by a term substitution technique. The system has reached a very good performance in comparison with other submitted systems.
Presenting a new approach for the fuzzy shortest path problem in network

Along with developments in computer sciences and new technologies, linear programming and network flows methods have been significantly applied. These are important discussions in operation research that address linear optimization and its application in network flows. Shortest path problem has been always one of the most practical problems in network analysis. By development of mathematical models, different algorithms have been offered for optimal routing given the parameters, characteristics and structure of network. In this research a proposed algorithm based on the node combination algorithm has been presented to solve the shortest path problem in the fuzzy environment by using the graded mean integration method. Node combination algorithm that sought to find the shortest path by node combination instead of labeling operation. It makes the procedure of finding shortest path very simple and understandable and coupled with saving system memory.
Semantic Representation of Provenance in Wikipedia

Wikis are often considered as being a wide source of information. However, identifying provenance information about their content is crucial, whether it is for computing trust in public wiki pages or to identify experts in corporate wikis. In this paper, we address this issue by providing a lightweight ontology for provenance management in wikis, based on the W7 model. Furthermore, we showcase the use of our model in a framework that computes provenance information in Wikipedia, also using DBpedia to compute provenance and contribution information per category, and not only per page.
A model for popularity dynamics to predict hot articles in discussion blog

It is interesting and informative to predict the set of articles that will be popular from the early observation stage. In this paper, we concentrate on the characteristics of hot articles and estimate the saturation point that is the earliest time the hits variation approaches zero. We have shown the statistical measures of our prediction method for popular articles, by observing the hit records from the birth time of the article. Our experiment showed that the more popular the subject article, the harder it is to identify such popular articles by observing only the early stage. The main contributions of this paper are as follows. We revealed the relationship between the amount of observation data and the predictability of popular articles. And We showed that there is a limit in predicting highly popular articles using partial knowledge. This implies the high popularity of online articles have common basic characteristics of a dynamic system that is hard to predict at the early stage.
Analysis of the immune response in infants hospitalized with viral bronchiolitis shows different Th1/Th2 profiles associated with respiratory syncytial virus and human rhinovirus

Severe bronchiolitis is often associated with the development of wheezing and asthma during childhood but the mechanisms behind the development of respiratory disorders after bronchiolitis remain controversial (1). The respiratory syncytial virus (RSV) and the human rhinovirus (HRV) are the most important etiologies of bronchiolitis (2, 3). Compared to RSV, HRV-infected infants display peculiar clinical characteristics and a correlation of HRV-bronchiolitis with asthma has been suggested (4-7). We report here the results of a preliminary investigation aimed at the evaluation of the ongoing T-cell responses in infants with bronchiolitis of different etiology. This article is protected by copyright. All rights reserved.
Linking Parental Support and Parental Control to Physical Activity Participation in Youth: The Mediating Role of Self-efficacy and Enjoyment

Identifying modifiable factors associated with physical activity (PA) is necessary to develop effective behaviour change interventions to promote PA. We examined the associations between parental support, parental control, youth’s self-efficacy, enjoyment, and PA participation inand out-of-school. Data for our cross-sectional study were collected via selfreport questionnaires from 602 youth (Mage=13.4 years; SD=.6) and analyzed using path analysis. We found that parental support and parental control indirectly influenced youth’s PA via self-efficacy and enjoyment. Specifically, parental control negatively influenced youth’s selfefficacy and enjoyment (β=-.12 to -.15), whereas parental support positively influenced youth’s self-efficacy and enjoyment (β=.18 to .31). Also, youth’s self-efficacy and enjoyment positively influenced PA performed inand out-of-school (β=.12 to .26). Our findings suggest parental supportive and controlling behaviours affect youth’s self-efficacy and enjoyment, which in turn influence PA participation in different settings. Promoting parental support, while reducing parental control, may effectively increase youth’s participation in PA. PARENTAL INFLUENCES AND YOUTH PHYSICAL ACTIVITY iv
Secure transmission medical data for pervasive healthcare system using android

Emerging technologies are transforming the workflows in pervasive healthcare enterprises. Pervasive Healthcare is a one of the developing technology within the pervasive computing paradigm. The presence of pervasive computing, consisting of wireless network gives innovative medium for data transmission of medical applications. We currently use a various wireless technology in healthcare domain. In the existing technology of e-Health has less security of Electronic Medical Records (EMR) and cannot access the medical records in wireless medium. An EMR is a digital version of the traditional paper-based medical record for an each patient's record. The EMR represents a medical record within a faculty can access the data, such as a doctor or a patient or administration. The accessing of information from the remote database should be high security; it should be a secured access of data by authorized persons. We propose a Pervasive Mobile Healthcare solve these problems and provide user to access the multimedia medical record from anywhere and anytime with security using Elliptical Curve Cryptography(ECC) algorithm, which includes authentication and access control. The authentication is allows the types of users who is authorized to use the application. Security is provided through the process of Encryption and decryption of data. This secured system will provide security in delivering the EMR of patients. Implementation here is done by using Android software and for database MySql is used in Server system. A Wi-Fi enabled mobile is used to receive or transmit the secured medical data as well as image retrieval. The novelty of my application deals with mobility where the users can able to access the secure information. The mobile application develop for real world environment.
Serotonin modulation of hippocampal activity

Article de synthese sur la modulation par la serotonine de l'activite electrophysiologique de l'hippocampe. Effet de la serotonine in vitro, mecanismes postsynaptiques, effet in vivo et greffes de raphe dans l'hippocampe
The Electronic Design Interchange Format EDIF: present and future

The authors review the present status and current developments of the Electronic Design Interchange Format, EDIF. EDIF is now the primary mechanism for transfer of connectivity and schematic data. However, real practical problems exist and are being tackled. Some of the difficulties that have arisen are reviewed and some solutions are discussed. Some of the new ideas being developed for inclusion in the new release of EDIF (Version 2 1 0) are introduced. <<ETX>>
Chern-Simons and WZNW Theories and the Quark-Gluon Plasma

Summation over hard thermal loops, by themselves and as insertions in higher order Feynman diagrams, is important in thermal perturbation theory for Quantum Chromodynamics, so that all contributions of a given order in the coupling constant can be consistently taken into account. I review some of the basic properties of hard thermal loops and how the generating functional for them is related to the eikonal for a Chern-Simons gauge theory, and using an auxiliary field, to the gauged Wess-Zumino-Novikov-Witten action. The Hamiltonian analysis of the effective action and a discussion of plasma waves are given. It is also pointed out that a possible expression for the magnetic mass term can be written in a closely related way.
Pretreatment on Initial Value of Image Restoration Models with Different Boundary Conditions

In this paper we present a simple but very effective pretreatment on the initial value applied to two kinds of time dependent image restoration model. Two kinds of images and two kinds of boundary conditions (BCs) are used for our numerical experiments. Numerical results demonstrate that the little change accelerates the convergence and gets a better restoration effect.
Topological features of gene regulatory networks predict patterns of natural diversity in environmental response

Molecular interactions affect the evolution of complex traits. For instance, adaptation may be constrained by pleiotropic or epistatic effects, both of which will be reflected in the structure of molecular interaction networks. To date, empirical studies investigating the role of molecular interactions in phenotypic evolution have been idiosyncratic, offering no clear patterns. Here, we investigated the network topology of genes putatively involved in local adaptation to two abiotic stressors—drought and cold—in Arabidopsis thaliana. Our findings suggest that the gene-interaction topologies for both cold and drought stress response are non-random, with genes that show genetic variation in drought response (GxE) being significantly more peripheral and cold response genes being significantly more central than genes not involved in either response. We suggest that the observed topologies reflect different constraints on the genetic pathways involved in the assayed phenotypes. The approach presented here may inform predictive models linking genetic variation in molecular signaling networks with phenotypic variation, specifically traits involved in environmental response. Significance Statement Our study focuses on genes whose transcriptional activity exhibits genetic variation in response to the environment, or “GxE. ” GxE is a widely observed phenomenon of critical importance to understanding the genotype-to-phenotype map, the evolution of natural populations, medical genetics, population response to climate change, and agricultural improvement. We investigated expression GxE in plant responses to two abiotic cues: cold and drought. We found that genes showing genetically variable response to cold stress are centrally located in regulatory networks whereas genes showing genetically variable response to drought stress are peripherally located in regulatory networks. This result suggests that selection is presented with vastly different mutational landscapes for shaping evolutionary or breeding response to these two important climatic factors
Combined Two-Stage Stochastic Programming and Receding Horizon Control Strategy for Microgrid Energy Management Considering Uncertainty

Microgrids (MGs) are presented as a cornerstone of smart grids. With the potential to integrate intermittent renewable energy sources (RES) in a flexible and environmental way, the MG concept has gained even more attention. Due to the randomness of RES, load, and electricity price in MG, the forecast errors of MGs will affect the performance of the power scheduling and the operating cost of an MG. In this paper, a combined stochastic programming and receding horizon control (SPRHC) strategy is proposed for microgrid energy management under uncertainty, which combines the advantages of two-stage stochastic programming (SP) and receding horizon control (RHC) strategy. With an SP strategy, a scheduling plan can be derived that minimizes the risk of uncertainty by involving the uncertainty of MG in the optimization model. With an RHC strategy, the uncertainty within the MG can be further compensated through a feedback mechanism with the lately updated forecast information. In our approach, a proper strategy is also proposed to maintain the SP model as a mixed integer linear constrained quadratic programming (MILCQP) problem, which is solvable without resorting to any heuristics algorithms. The results of numerical experiments explicitly demonstrate the superiority of the proposed strategy for both island and grid-connected operating modes of an MG.
Knowledge, Attitude and Practice Regarding Organic Solvents among Printing Workers in Hong Kong

Knowledge, Attitude and Practice Regarding Organic Solvents among Printing Workers in Hong Kong: Ignatius Tak‐Sun YU, et al. Department of Community & Family Medicine, The Chinese University of Hong Kong, China—To find out the prevalence of good knowledge, appropriate attitude and safe practice among printing workers exposed to organic solvents in Hong Kong, and to see if safe practice was influenced by the knowledge of and the attitude towards the harmful effects of organic solvents as well as other factors. The survey was conducted in a sample of 501 male printing workers from 28 factories in Hong Kong. The knowledge of and attitude towards the harmful effects of organic solvents, as well as the good practices adopted by the workers when handling solvents were explored using a questionnaire. Multiple logistic regression analysis was conducted to identify the major factors that influenced the knowledge, attitude and practice of workers. The prevalence of good knowledge, appropriate attitude and safe practice was low, being 20.4%, 38.4% and 22.0% respectively. Good knowledge was positively associated with awareness of the relevant legislation and past drinking behavior and negatively associated with current smoking. Appropriate attitude depended on having good knowledge and younger age. Safe practice did not depend on knowledge and attitude, but was positively associated with being informed of safety precautions and being supplied with chemical information by supervisors. The majority of workers believed that their employers, the Government and other statutory bodies should be responsible for providing information on chemicals, but very few of them actually obtained information from these sources. More workers preferred publications and talks rather than television as the means of obtaining further knowledge on chemicals. Front line supervisors have a pivotal role to play in improving safe practices of workers by informing them of the necessary precautions and supplying the relevant chemical information.
The Binormalized Data-Reusing LMS Algorithm

A new algorithm, the binormalized data-reusing least mean squares (LMS) algorithm is presented. The new algorithm has been found to converge faster than other LMS-like algorithms, such as the Normalized LMS algorithm and several data-reusing LMS algorithms, when the input signal is highly correlated. The computational complexity of this new algorithm is only slightly higher than a recently proposed normalized new data-reusing LMS algorithm.
First Optical Images of Circumstellar Dust Surrounding the Debris Disk Candidate HD 32297

Near-infrared imaging with the Hubble Space Telescope recently revealed a circumstellar dust disk around the A star HD 32297. Dust-scattered light is detected as far as 400 AU radius, and the linear morphology is consistent with a disk ~10° away from an edge-on orientation. Here we present the first optical images that show the dust-scattered light morphology from 560 to 1680 AU radius. The position angle of the putative disk midplane diverges by ~31°, and the color of dust scattering is most likely blue. We associate HD 32297 with a wall of interstellar gas and the enigmatic region south of the Taurus molecular cloud. We propose that the extreme asymmetries and blue disk color originate from a collision with a clump of interstellar material as HD 32297 moves southward, and discuss evidence consistent with an age of 30 Myr or younger.
Innate Immune Activation and Subversion of Mammalian Functions by Leishmania Lipophosphoglycan

Leishmania promastigotes express several prominent glycoconjugates, either secreted or anchored to the parasite surface. Of these lipophosphoglycan (LPG) is the most abundant, and along with other phosphoglycan-bearing molecules, plays important roles in parasite infectivity and pathogenesis in both the sand fly and the mammalian host. Besides its contribution for parasite survival in the sand fly vector, LPG is important for modulation the host immune responses to favor the establishment of mammalian infection. This review will summarize the current knowledge regarding the role of LPG in Leishmania infectivity, focusing on the interaction of LPG and innate immune cells and in the subversion of mammalian functions by this molecule.
Escherichia coli exonuclease III enhances long PCR amplification of damaged DNA templates.

Recent development of the long PCR technology has provided an invaluable tool in many areas of molecular biology. However, long PCR amplification fails whenever the DNA template is imperfectly preserved. We report that Escherichia coli exonuclease III, a major repair enzyme in bacteria, strikingly improves the long PCR amplification of damaged DNA templates. Escherichia coli exonuclease III permitted or improved long PCR amplification with DNA samples submitted to different in vitro treatments known to induce DNA strand breaks and/or apurinic/apyrimidinic (AP) sites, including high temperature (99 degrees C), depurination at low pH and near-UV radiation. Exonuclease III also permitted or improved amplification with DNA samples that had been isolated several years ago by the phenol/chloroform method. Amelioration of long PCR amplification was achieved for PCR products ranging in size from 5 to 15.4 kb and with DNA target sequences located either within mitochondrial DNA or the nuclear genome. Exonuclease III increased the amplification of damaged templates using either rTth DNA polymerase alone or rTth plus Vent DNA polymerases or TAQ: plus PWO: DNA polymerases. However, exonuclease III could not improve PCR amplification from extensively damaged DNA samples. In conclusion, supplementation of long PCR mixes with E.COLI: exonuclease III may represent a major technical advance whenever DNA samples have been partly damaged during isolation or subsequent storage.
A Fully Integrated Dual-Band Low Noise Amplifier for IEEE 802.11 and Hiper LAN Application

A fully-integrated dual-band Low Noise Amplifier (LNA), which can be used for IEEE 802.11 and Hiper LAN applications, was investigated in this paper. The proposed LAN was implemented entirely pm a single chip based on a standard 0.18 ? m 1P6M CMOS process. It draws 13 mA current from a 1.5-V voltage supply and achieves power gains of 17 and 10 dB, noise figure of 3.7 and 4.2 dB at 2.4 and 5.3 GHz respectively.
Surface-Illuminant Ambiguity and Color Constancy: Effects of Scene Complexity and Depth Cues

Two experiments were conducted to study how scene complexity and cues to depth affect human color constancy. Specifically, two levels of scene complexity were compared. The low-complexity scene contained two walls with the same surface reflectance and a test patch which provided no information about the illuminant. In addition to the surfaces visible in the low-complexity scene, the high-complexity scene contained two rectangular solid objects and 24 paper samples with diverse surface reflectances. Observers viewed illuminated objects in an experimental chamber and adjusted the test patch until it appeared achromatic. Achromatic settings made under two different illuminants were used to compute an index that quantified the degree of constancy. Two experiments were conducted: one in which observers viewed the stimuli directly, and one in which they viewed the scenes through an optical system that reduced cues to depth. In each experiment, constancy was assessed for two conditions. In the valid-cue condition, many cues provided valid information about the illuminant change. In the invalid-cue condition, some image cues provided invalid information. Four broad conclusions are drawn from the data: (a) constancy is generally better in the valid-cue condition than in the invalid-cue condition; (b) for the stimulus configuration used, increasing image complexity has little effect in the valid-cue condition but leads to increased constancy in the invalid-cue condition; (c) for the stimulus configuration used, reducing cues to depth has little effect for either constancy condition; and (d) there is moderate individual variation in the degree of constancy exhibited, particularly in the degree to which the complexity manipulation affects performance.