Miracle-dz/UniFAR-FTUs huggingface dataset:
Electric dipole moments of atoms, molecules, nuclei, and particles

A permanent electric dipole moment (EDM) of a particle or system is a separation of charge along its angular momentum axis and is a direct signal of T violation and, assuming CPT symmetry, CP violation. For over 60 years EDMs have been studied, first as a signal of a parity-symmetry violation and then as a signal of CP violation that would clarify its role in nature and in theory. Contemporary motivations include the role that CP violation plays in explaining the cosmological matter-antimatter asymmetry and the search for new physics. Experiments on a variety of systems have become ever-more sensitive, but provide only upper limits on EDMs, and theory at several scales is crucial to interpret these limits. Nuclear theory provides connections from standard-model and beyond-standard-model physics to the observable EDMs, and atomic and molecular theory reveal how CP violation is manifest in these systems. EDM results in hadronic systems require that the standard-model QCD parameter of θ¯ must be exceptionally small, which could be explained by the existence of axions, also a candidate dark-matter particle. Theoretical results on electroweak baryogenesis show that new physics is needed to explain the dominance of matter in the Universe. Experimental and theoretical efforts continue to expand with new ideas and new questions, and this review provides a broad overview of theoretical motivations and interpretations as well as details about experimental techniques, experiments, and prospects. The intent is to provide specifics and context as this exciting field moves forward.
Critical field-exponents for secure message-passing in modular networks

We study secure message-passing in the presence of multiple adversaries in modular networks. We assume a dominant fraction of nodes in each module have the same vulnerability, i.e., the same entity spying on them. We find both analytically and via simulations that the links between the modules (interlinks) have effects analogous to a magnetic field in a spin-system in that for any amount of interlinks the system no longer undergoes a phase transition. We then define the exponents δ, which relates the order parameter (the size of the giant secure component) at the critical point to the field strength (average number of interlinks per node), and γ, which describes the susceptibility near criticality. These are found to be δ = 2 and γ = 1 (with the scaling of the order parameter near the critical point given by β = 1). When two or more vulnerabilities are equally present in a module we find δ = 1 and γ = 0 (with β ≥ 2). Apart from defining a previously unidentified universality class, these exponents show that increasing connections between modules is more beneficial for security than increasing connections within modules. We also measure the correlation critical exponent ν, and the upper critical dimension dc, finding that ν d c = 3 as for ordinary percolation, suggesting that for secure message-passing dc = 6. These results provide an interesting analogy between secure message-passing in modular networks and the physics of magnetic spin-systems.
New type of controller: the proportional integral minus delay controller

In the design of a control system, the derivative controller is often required to obtain a quick response. However, when the control system is subject to noise inputs, the functioning of the derivative controller may be jeopardized owing to its sensitivity to high-frequency noise. In order to overcome this problem, a new type of controller, called the proportional-integral-minus-delay (PIMD) controller is proposed in this paper. It is shown that in addition to exhibiting almost the same characteristics as the conventional proportional-plus-integral-plus-derivative (PID) controller, the PIMD controller is less sensitive to high-frequency noise. It seems that an appropriate PIMD controller would be a good replacement for a PID controller. The output time responses of the closed-loop system with a PIMD controller and the frequency-response characteristics of a PIMD controller are obtained by computer simulation.
Orbital currents in insulating and doped antiferromagnets

We describe square lattice spin liquids which break time-reversal symmetry, while preserving translational symmetry. The states are distinguished by the manner in which they transform under mirror symmetries. All the states have non-zero scalar spin chirality, which implies the appearance of spontaneous orbital charge currents in the bulk (even in the insulator); but in some cases, orbital currents are non-zero only in a formulation with three orbitals per unit cell. The states are formulated using both the bosonic and fermionic spinon approaches. We describe states with $\mathbb{Z}_2$ and U(1) bulk topological order, and the chiral spin liquid with semionic excitations. The chiral spin liquid has no orbital currents in the one-band formulation, but does have orbital currents in the three-band formulation. We discuss application to the cuprate superconductors, after postulating that the broken time-reversal and mirror symmetries persist into confining phases which may also break other symmetries. In particular, the broken symmetries of the chiral spin liquid could persist into the Neel state.
The SILCC project – V. The impact of magnetic fields on the chemistry and the formation of molecular clouds

Magnetic fields are ubiquitously observed in the interstellar medium (ISM) of present-day star-forming galaxies with dynamically relevant energy densities. Using three-dimensional magneto-hydrodynamic (MHD) simulations of the supernova (SN) driven ISM in the flux-freezing approximation (ideal MHD) we investigate the impact of the magnetic field on the chemical and dynamical evolution of the gas, fragmentation and the formation of molecular clouds. We follow the chemistry with a network of six species (H$^{+}$, H, H$_2$, C$^+$, CO, free electrons) including local shielding effects. We find that magnetic fields thicken the disc by a factor of a few to a scale height of $\sim100\,\mathrm{pc}$, delay the formation of dense (and molecular) gas by $\sim25\,\mathrm{Myr}$ and result in differently shaped gas structures. The magnetised gas fragments into fewer clumps, which are initially at subcritical mass-to-flux ratios, $M/\Phi\approx0.3(M/\Phi)_\mathrm{crit}$, and accrete gas preferentially parallel to the magnetic field lines until supercritial mass-to-flux ratios of up to order 10 are reached. The accretion rates onto molecular clouds scale with $\dot{M}\propto M^{1.5}$. The median of the inter-cloud velocity dispersion is $\sim2-5\,\mathrm{km\,s}^{-1}$ and lower than the internal velocity dispersion in the clouds ($\sim3-7\,\mathrm{km\,s}^{-1}$). However, individual cloud-cloud collisions occur at speeds of a few $10\,\mathrm{km\,s}^{-1}$.
Gauging Metallicity of Diffuse Gas under an Uncertain Ionizing Radiation Field

Gas metallicity is a key quantity used to determine the physical conditions of gaseous clouds in a wide range of astronomical environments, including interstellar and intergalactic space. In particular, considerable effort in circumgalactic medium (CGM) studies focuses on metallicity measurements because gas metallicity serves as a critical discriminator for whether the observed heavy ions in the CGM originate in chemically enriched outflows or in more chemically pristine gas accreted from the intergalactic medium. However, because the gas is ionized, a necessary first step in determining CGM metallicity is to constrain the ionization state of the gas which, in addition to gas density, depends on the ultraviolet background radiation field (UVB). While it is generally acknowledged that both the intensity and spectral slope of the UVB are uncertain, the impact of an uncertain spectral slope has not been properly addressed in the literature. This Letter shows that adopting a different spectral slope can result in an order of magnitude difference in the inferred CGM metallicity. Specifically, a harder UVB spectrum leads to a higher estimated gas metallicity for a given set of observed ionic column densities. Therefore, such systematic uncertainties must be folded into the error budget for metallicity estimates of ionized gas. An initial study shows that empirical diagnostics are available for discriminating between hard and soft ionizing spectra. Applying these diagnostics helps reduce the systematic uncertainties in CGM metallicity estimates.
Association of fall rate and functional status by APOE genotype in cancer survivors after exercise intervention.

PURPOSE/OBJECTIVES Cancer treatment survivors often report impaired functioning and increased falls. Not all survivors experience the same symptom burden, suggesting individual susceptibilities. APOE genotype is a potential genetic risk factor for cancer treatment related side effects. Lifestyle factors such as physical activity can mitigate the effect of APOE genotype on measures of clinical interest in individuals without a history of cancer. We tested the hypothesis that APOE genotype influences cancer treatment related side effects and symptoms as well as response to exercise intervention. MATERIALS AND METHODS Data from a subsample of a study of fall prevention exercise in post-treatment female cancer survivors aged 50-75 years old (https://clinicaltrials.gov NCT01635413) were used to conduct a secondary data analysis. ApoE genotype was determined by serum sampling. Physical functioning, frequency of falls, and symptom burden were assessed using survey instruments. RESULTS Data from 126 female cancer survivors a median of 49 months out from cancer diagnosis were analyzed. ApoE4 carriers trended toward a higher fall rate at baseline (p = 0.059), but after exercise intervention had a fall rate lower than E4 non-carriers both immediately after structured intervention (p = 0.013) and after 6 months of follow up (p = 0.002). E2 carriers did not show improved measures of depressive symptoms and self-report disability after exercise intervention. E3 homozygotes showed increased self report physical activity after the 6 month exercise intervention, but E4 and E2 carriers did not. CONCLUSIONS APOE genotype may modulate cancer treatment related side effects and symptoms and response to exercise intervention.
Circulating Serum Cystatin C as an Independent Risk Biomarker for Vascular Endothelial Dysfunction in Patients with COVID-19-Associated Multisystem Inflammatory Syndrome in Children (MIS-C): A Prospective Observational Study

Introduction: Multisystem inflammatory syndrome in children (MIS-C) is a new clinical entity that has emerged in the context of the COVID-19 pandemic. Despite the less severe course of the disease, varying degrees of cardiovascular events may occur in MIS-C; however, data on vascular changes occurring in MIS-C are still lacking. Endothelial dysfunction (ED) is thought to be one of the key risk factors contributing to MIS-C. Background: We conducted a prospective observational study. We investigated possible manifestations of cardiac and endothelial involvement in MIS-C after the treatment of the acute stage and potential predictive biomarkers in patients with MIS-C. Methods: Twenty-seven consecutive pediatric subjects (≥9 years), at least three months post-treated MIS-C of varying severity, in a stable condition, and twenty-three age- and sex-matched healthy individuals (HI), were enrolled. A combined non-invasive diagnostic approach was used to assess endothelial function as well as markers of organ damage using cardiac examination and measurement of the reactive hyperemia index (RHI), by recording the post- to pre-occlusion pulsatile volume changes and biomarkers related to ED and cardiac disease. Results: MIS-C patients exhibited a significantly lower RHI (indicative of more severe ED) than those in HI (1.32 vs. 1.80; p = 0.001). The cutoff of RHI ≤ 1.4 was independently associated with a higher cardiovascular risk. Age and biomarkers significantly correlated with RHI, while serum cystatin C (Cys C) levels were independently associated with a diminished RHI, suggesting Cys C as a surrogate marker of ED in MIS-C. Conclusions: Patients after MIS-C display evidence of ED, as shown by a diminished RHI and altered endothelial biomarkers. Cys C was identified as an independent indicator for the development of cardiovascular disease. The combination of these factors has the potential to better predict the cardiovascular consequences of MIS-C. Our study suggests that ED may be implicated in the pathophysiology of this disease.
Deformation Process of a Water Droplet Impinging on a Solid Surface

We are concerned with numerical simulations of the deformation behavior of a liquid droplet impinging on a flat solid surface, as well as the flow field inside the droplet. In the present situation, the case where a droplet impinges on the surface at room temperature with a speed in the order of a few [m/s], is treated. These simulations were performed using the MAC-type solution method to solve a finite-differencing approximation of the Navier-Stokes equations governing an axisymmetric and incompressible fluid flow. For the first case where the liquid is water, the liquid film formed by the droplet impinging on the solid surface flows radially along it and expands in a fairly thin discoid-like shape. Thereafter, the liquid flow shows a tendency to stagnate at the periphery of the circular film, with the result that water is concentrated there is a doughnut-like shape. Subsequently, the water begins to flow backwards toward the center where it accumulates in the central region. For the second case where a n-heptane droplet impinges the surface, the film continues to spread monotonically up to a maximum diameter and there is no recoiling process to cause a backwards flow towards the central region.
ISAP+: ISAP with Fast Authentication

This paper analyses the lightweight, sponge-based NAEAD mode ISAP , one of the ﬁnalists of the NIST Lightweight Cryptography (LWC) standardisation project, that achieves high-throughput with inherent protection against diﬀerential power analysis (DPA). We observe that ISAP requires 256-bit capacity in the authentication module to satisfy the NIST LWC security criteria. In this paper, we study the analysis carefully and observe that this is primarily due to the collision in the associated data part of the hash function which can be used in the forgery of the mode. However, the same is not applicable to the ciphertext part of the hash function because a collision in the ciphertext part does not always lead to a forgery. In this context, we deﬁne a new security notion, named 2PI+ security, which is a strictly stronger notion than the collision security, and show that the security of a class of encrypt-then-hash based MAC type of authenticated encryptions, that includes ISAP , reduces to the 2PI+ security of the underlying hash function used in the authentication module. Next we investigate and observe that a feed-forward variant of the generic sponge hash achieves better 2PI+ security as compared to the generic sponge hash. We use this fact to present a close variant of ISAP , named ISAP+ , which is structurally similar to ISAP , except that it uses the feed-forward variant of the generic sponge hash in the authentication module. This improves the overall security of the mode, and hence we can set the capacity of the ciphertext part to 192 bits (to achieve a higher throughput) and yet satisfy the NIST LWC security criteria.
Integrable scalar cosmologies.II. Can they fit into Gauged Extended Supergravity or be encoded in N=1 superpotentials?

The question whether the integrable one-field cosmologies classified in a previous paper by Fré, Sagnotti and Sorin can be embedded as consistent one-field truncations into Extended Gauged Supergravity or in N = 1 supergravity gauged by a superpotential without the use of D-terms is addressed in this paper. The answer is that such an embedding is very difficult and rare but not impossible. Indeed, we were able to find two examples of integrable models embedded in supergravity in this way. Both examples are fitted into N = 1 supergravity by means of a very specific and interesting choice of the superpotentialW(z). The question whether there are examples of such an embedding in Extended Gauged Supergravity remains open. In the present paper, relying on the embedding tensor formalism we classified all gaugings of the N = 2 STU model, confirming, in the absence on hypermultiplets, the uniqueness of the stable de Sitter vacuum found several years ago by Fré, Trigiante and Van Proeyen and excluding the embedding of any integrable cosmological model. A detailed analysis of the space of exact solutions of the first supergravity-embedded integrable cosmological model revealed several new features worth an in-depth consideration. When the scalar potential has an extremum at a negative value, the Universe necessarily collapses into a Big Crunch notwithstanding its spatial flatness. The causal structure of these Universes is quite different from that of * Corresponding author. E-mail addresses: fre@to.infn. it (P. Fré), sorin@theor.jinr. ru (A.S. Sorin), mario.trigiante@gmail.com (M. Trigiante). 1 Prof. Fré is presently fulfilling the duties of Scientific Counselor of the Italian Embassy in the Russian Federation, Denezhnij pereulok, 5, 121002 Moscow, Russia. http://dx.doi. org/10.1016/j.nuclphysb. 2014.01. 024 0550-3213/© 2014 The Authors. Published by Elsevier B.V. This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/3.0/). Funded by SCOAP3. 92 P. Fré et al. / Nuclear Physics B 881 (2014) 91–180 the closed, positive curved, Universe: indeed, in this case the particle and event horizons do not coincide and develop complicated patterns. The cosmological consequences of this unexpected mechanism deserve careful consideration. © 2014 The Authors. Published by Elsevier B.V. This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/3.0/). Funded by SCOAP3.
Clinical Epidemiology, Pathology, and Molecular Investigation of Lumpy Skin Disease Outbreaks in Bangladesh during 2020–2021 Indicate the Re-Emergence of an Old African Strain

Lumpy skin disease (LSD) emerged in Bangladesh in mid-2019, leading to great economic losses for cattle farmers. This study describes the recent occurrence of the LSDV in Bangladesh and examines the clinical manifestation of the disease in local cattle breeds, characteristic epidemiological features, and pathological findings in affected animals. In addition, a full-genome sequencing of two local LSDV isolates was carried out. A total of 565 animals from 88 households were investigated, and 165 samples (skin lesions, saliva, nasal discharge, feces, and milk) were collected for virus detection. Pathology and immunohistochemistry were performed on nodule biopsies. Fever, nodular skin lesions, and swelling of the joints were the most common clinical manifestations. Skin lesions had a higher concentration of viral DNA compared to other sample types and were therefore selected for virus isolation and characterization. Pathology of the LSD skin nodules comprised a granulomatous reaction in the dermis and hypodermis that extended to the surrounding tissues. Development of the skin lesions started with swelling of keratinocytes with cytoplasmic vacuolation, vasculitis, panniculitis, thrombosis, and infarction. Altogether, the LSDV produced transmural, hemorrhagic, necrotizing, proliferative and ulcerative dermatitis. The LSD viral antigen was detected occasionally in the macrophages, epithelial cells, and vascular smooth muscle cells. The complete genome sequence analysis revealed that the two Bangladeshi field strains (BD-V392.1 and BD-V395.1) were distinct from the contemporary field strains and were closely related to the ancestral African Neethling strain. The findings of this study will improve the diagnosis, monitoring, and control of LSD in Bangladesh.
The orphan nuclear receptor Nor1/Nr4a3 is a negative regulator of (cid:2) -cell mass

The Nr4a subfamily of nuclear receptor comprises three members in mammalian cells: Nur77/Nr4a1, Nurr1/Nr4a2, and Nor1/Nr4a3. Nr4a proteins play key roles in the regulation of glucose homeostasis in peripheral metabolic tissues. However, their biological functions in (cid:2) -cells remain relatively uncharac-terized. Here we sought to investigate the potential role of Nor1 in the regulation of (cid:2) -cell mass and, in particular, (cid:2) -cell survival/apoptosis. We used histological analysis to examine the consequences of genetic deletion of either Nur77 and Nor1 on (cid:2) -cell mass, investigated the expression patterns of Nr4as in human islets and INS cells and performed gain- and loss-of-function experiments to further characterize the role of Nor1 in (cid:2) -cell apoptosis. Surprisingly, Nor1 knockout mice displayed increased (cid:2) -cell mass, whereas mice with genetic deletion of Nur77 did not exhibit any significant differences compared with their WT littermates. The increase in (cid:2) -cell mass in
Creating the universe from brane-antibrane annihilation

When p-dimensional branes annihilate with antibranes in the early universe, as in brane-antibrane inflation, stable $(p\ensuremath{-}2)$-dimensional branes can appear in the final state. We reexamine the possibility that one of these $(p\ensuremath{-}2)$-branes could be our universe. In the low energy effective theory, the final state branes are cosmic string defects of the complex tachyon field which describes the instability of the initial state. We quantify the dynamics of formation of these vortices. This information is then used to estimate the production of massless gauge bosons on the final branes, due to their coupling to the time-dependent tachyon background, which would provide a mechanism for reheating after inflation. We improve upon previous estimates indicating that this can be an efficient reheating mechanism for observers on the brane.
Visualising the heterogeneity in phenotype, disease progression and drug response in a large population with type 2 diabetes

1 Division of Population Health and Genomics, School of Medicine, University of Dundee, Dundee, UK 2 Wellcome Centre for Human Genetics, University of Oxford, Oxford, UK 3 Novo Nordisk Center for Protein Research, University of Copenhagen, Copenhagen, Denmark 4 Madras Diabetes Research Foundation, Chennai, India 5 Institute of Biomedical and Clinical Science, Royal Devon and Exeter Hospital, University of Exeter,UK
Gamma-ray imaging system for real-time measurements in nuclear waste characterisation

A compact, portable and large field-of-view gamma camera that is able to identify, locate and quantify gamma-ray emitting radioisotopes in real-time has been developed. The device delivers spectroscopic and imaging capabilities that enable its use it in a variety of nuclear waste characterisation scenarios, such as radioactivity monitoring in nuclear power plants and more specifically for the decommissioning of nuclear facilities. The technical development of this apparatus and some examples of its application in field measurements are reported in this article. The performance of the presented gamma-camera is also benchmarked against other conventional techniques.