Miracle-dz/UniFAR-FTUs huggingface dataset:
Transcriptome and Proteome Analysis Revealed the Influence of High-Molecular-Weight Glutenin Subunits (HMW-GSs) Deficiency on Expression of Storage Substances and the Potential Regulatory Mechanism of HMW-GSs

The processing quality of wheat is affected by seed storage substances, such as protein and starch. High-molecular-weight glutenin subunits (HMW-GSs) are the major components of wheat seed storage proteins (SSPs); they are also key determinators of wheat end-use quality. However, the effects of HMW-GSs absence on the expression of other storage substances and the regulation mechanism of HMW-GSs are still limited. Previously, a wheat transgenic line LH-11 with complete deletions of HMW-GSs was obtained through introducing an exogenous gene Glu-1Ebx to the wild-type cultivar Bobwhite by transgenic approach. In this study, comparative seed transcriptomics and proteomics of transgenic and non-transgenic lines at different seed developmental stages were carried out to explore the changes in genes and proteins and the underlying regulatory mechanism. Results revealed that a number of genes, including genes related to SSPs, carbohydrates metabolism, amino acids metabolism, transcription, translation, and protein process were differentially enriched. Seed storage proteins displayed differential expression patterns between the transgenic and non-transgenic line, a major rise in the expression levels of gliadins were observed at 21 and 28 days post anthesis (DPA) in the transgenic line. Changes in expressions of low-molecular-weight glutenins (LMW-GSs), avenin-like proteins (ALPs), lipid transfer proteins (LTPs), and protease inhibitors (PIs) were also observed. In addition, genes related to carbohydrate metabolism were differentially expressed, which probably leads to a difference in starch component and deposition. A list of gene categories participating in the accumulation of SSPs was proposed according to the transcriptome and proteome data. Six genes from the MYB and eight genes from the NAC transcription families are likely important regulators of HMW-GSs accumulation. This study will provide data support for understanding the regulatory network of wheat storage substances. The screened candidate genes can lay a foundation for further research on the regulation mechanism of HMW-GSs.
An improved sub‐harmonic to harmonic ratio method for pitch estimation and Shadja detection

In this paper, we have presented an improved Sub‐Harmonic to Harmonic ratio (SHR) algorithm using the Genetic algorithm (GA) for pitch estimation of audio recordings of various ragas. Then we study the problem of Shadja identification using machine learning with the help of feature extraction and classification. The extraction of features from the raga signal is done with the help of statistical analysis of pitch estimation and these features are classified using a Neural Network (NN). Here, the training of NN is accomplished by Gray Wolf Optimization (GWO) algorithm for, determining the weights. Performance of the proposed Sa detection algorithm is analyzed by comparing the developed NN using Gray Wolf Optimization (GWO) models with the conventional models such as Levenberg Marquardt based NN (LM‐NN), Gradient Descent based (GD‐NN), Particle Swarm Optimization based NN (PSO‐NN) and FireFly based NN (FF‐NN) in terms of positive and negative performance measures.
An evaluation of Jung’s psychological types and their relationship to psychopathology

This paper compares Jung’s original conception of psychological types with the modern Myers-Briggs Type Indicator (MBTI) and the Big Three and Big Five personality traits in order to evaluate their relationship to various forms of psychopathology. In doing so it becomes apparent that Jung’s original conception of psychological types are fundamentally different to both the MBTI and the Big Three and Big Five personality traits. Modern personality research focuses on categorisation for the purposes of defining diagnostic categories and treatment strategies but this was not Jung’s purpose in describing the types. Jung’s differentiation of the two psychological types and the four functions did not imply any value judgement or that one was more prone to psychopathology than another. Furthermore, Jung’s understanding of the introverted and extraverted types as fundamentally different ways of perceiving and comprehending the world has been overlooked by modern personality trait psychology,possibly to the detriment of the introverted type in our extravert-oriented society.
Is SVS 13 the Exciting Source of the HH 7-11 Flow?

Since 1976 it has been believed that the Herbig-Haro (HH) objects 7-11 are excited by SVS 13, an infrared source located approximately along the line defined by this chain of nebulosities. It is well established that the exciting sources of HH flows are frequently detected in the centimeter continuum. When observed with high angular resolution, these radio sources appear as subarcsecond thermal jets that are elongated in the direction of the outflow axis. We present sensitive, high angular resolution VLA observations of the region that show radio continuum emission associated with SVS 13 but also reveal at about 6'' to its southwest the presence of a second radio source previously undetected at other wavelengths. This source is better aligned with the axis defined by the HH 7-11 outflow and also exhibits an elongation along this axis. We favor this new object as the most likely exciting source of this classic HH system. However, high angular resolution molecular observations of the region are required to test this proposition.
Effect of the Lorentz force on cylinder drag reduction and its optimal location

In this paper, the effects of the Lorentz force on drag reduction in a circular cylinder and its optimal location on the surface have been studied. The Lorentz force influence is found to be composed of two opposite parts: one acts directly on the cylinder and is named as the wall Lorentz force and the other operates on the fluid near the cylinder surface and is called the field Lorentz force. The wall Lorentz force leads to the generation of thrust, while the field Lorentz force results in a pressure drag increase. The former dominates the drag variation. Therefore, the drag may become negative (thrust) with large enough Lorentz forces. Moreover, the maximum thrust and the pressure drag location under the effects of wall and field Lorentz forces are found to be the same, θ = ± 90°. However, the optimal location of drag reduction under the total effects of wall and field Lorentz forces is found to be in the central area of the flow separation coverage on the cylinder surface for Re = 100–200.
Soy Food Consumption Is Inversely Associated with Handgrip Strength: Results from the TCLSIH Cohort Study

Background: Soy foods contain high levels of soy protein or isoflavones, which can stimulate muscle protein synthesis and increase antioxidant capacity, and thus ameliorate muscle strength decline. However, data from epidemiological studies investigating the association of habitual soy food consumption with muscle strength decline among general Chinese adults are limited. Methods: This study included 29,525 participants (mean age: 41.6 years; 16,933 (53.8%) males). Soy food consumption was evaluated using a validated 100-item food frequency questionnaire. Handgrip strength (HGS) was assessed with a hand dynamometer. Analysis of covariance were performed to assess the multivariable-adjusted least square means (LSM) and 95% confidence interval (CI) for HGS. Results: The multiple adjusted LSM (95% CI) of HGS across soy food consumption were 35.5 (34.2, 37.1) kg for <1 time per week, 36.1 (34.6, 37.6) kg for 1 time per week, 36.3 (34.8, 37.8) kg for 2–3 times per week, and 36.6 (35.1, 38.0) kg for ≥4 times per week (p for trend < 0.001). Compared to participants with soy food consumption less than one time per week, the multiple adjusted odds ratio (95% CI) of low HGS was 0.638 (0.485, 0.836) when the weekly consumption was ≥ 4 times (p for trend < 0.01). Conclusions: Higher habitual soy food consumption was positively associated with HGS in general Chinese adults. Consumption of soy foods may have beneficial effects on muscle health.
A Characteristic Property of the Poisson Distribution

Abstract Suppose that N is a nonnegative, integer-valued random variable and that the conditional distribution of N 1, ···, N m (given N) is multinomial. Then, according to a result by Moran and Renyi, N 1 and N 2 are independent if and only if N has a Poisson distribution. A new proof is given that uses only the generating function of a single variable.
Buffer-Based High-Coverage and Low-Overhead Request Event Monitoring in the Cloud

Request latency directly affects the performance of modern cloud applications. Due to various causes in hosts and networks, requests can suffer from request latency anomalies (RLAs), which may violate the Service-Level Agreement. However, existing performance monitoring tools have incomplete coverage and inconsistent semantics for monitoring requests and cannot accurately diagnose RLAs. This paper presents <italic>BufScope</italic>, a high-coverage and low-overhead request event monitoring system, which monitors <italic>buffers</italic> to capture most RLA-related abnormal events with consistent request-level semantics in the end-to-end datapath of request. First, <italic>BufScope</italic> models the datapath of request as a buffer chain and defines events based on three properties of buffers, so as to <italic>end-to-end monitor</italic> the root causes of RLA. Then, to achieve <italic>consistent semantics</italic> for captured events, <italic>BufScope</italic> designs a request-level semantics injection mechanism to make events captured in networks have the victim requests’ ID. Finally, <italic>BufScope</italic> offloads the semantics operations and event collection in software to SmartNICs for <italic>low CPU overhead</italic>. We have implemented <italic>BufScope</italic> on commodity SmartNICs and programmable switches. Evaluation results show that <italic>BufScope</italic> can diagnose 98% RLAs with < 0.08% network bandwidth overhead and 0.6% application throughput decline.
Nonlinear regression for modeling censored one-dimensional concentration profiles of fugitive dust plumes

Dust plumes were generated by farm equipment during standard field preparations and harvest operations. Light detection and ranging (lidar) measurements of dust particle concentrations in the plumes were censored by an upper detection limit. The nonstandardized Gaussian curve, with range values as the argument, was used as a model for the one-dimensional plume profile. Maximum likelihood estimates for the Gaussian plume equation were found in order to make inferences concerning plume characteristics.
A simple stochastic cluster dynamics: rigorous results

Motivated by the Swendsen-Wang algorithm for the Ising model with no external magnetic field the authors consider a particle system on a discrete lattice evolving according to the following parallel algorithm: at each time step connected clusters of particles are removed with probability 1/2 and at each empty site a particle is created with probability p. Due to the presence of arbitrarily large clusters the interaction can have an arbitrary range. In the one-dimensional case they solve the model completely by means of a novel path expansion in spacetime. In the two-dimensional case they show that, due to strong time correlation, the probability of having a large cluster of particles does not rapidly decay exponentially in the cardinality of the cluster even for p very small. They then prove ergodicity for 1-p close to zero.
Thorough Characterization of ETHQB3.5, a QTL Involved in Melon Fruit Climacteric Behavior and Aroma Volatile Composition

The effect of the QTL involved in climacteric ripening ETHQB3.5 on the fruit VOC composition was studied using a set of Near-Isogenic Lines (NILs) containing overlapping introgressions from the Korean accession PI 16375 on the chromosome 3 in the climacteric ‘Piel de Sapo’ (PS) genetic background. ETHQB3.5 was mapped in an interval of 1.24 Mb that contained a NAC transcription factor. NIL fruits also showed differences in VOC composition belonging to acetate esters, non-acetate esters, and sulfur-derived families. Cosegregation of VOC composition (23 out of 48 total QTLs were mapped) and climacteric ripening was observed, suggesting a pleiotropic effect of ETHQB3.5. On the other hand, other VOCs (mainly alkanes, aldehydes, and ketones) showed a pattern of variation independent of ETHQB3.5 effects, indicating the presence of other genes controlling non-climacteric ripening VOCs. Network correlation analysis and hierarchical clustering found groups of highly correlated compounds and confirmed the involvement of the climacteric differences in compound classes and VOC differences. The modification of melon VOCs may be achieved with or without interfering with its physiological behavior, but it is likely that high relative concentrations of some type of ethylene-dependent esters could be achieved in climacteric cultivars.
Series expansions for the electric and magnetic fields produced by a line current source

The electric and magnetic fields that an overhead infinitely long line current produces at the surface of the Earth can be expressed as inverse Fourier integrals over a horizontal wave number. In the quasi‐static approximation acceptable in most applications and assuming a uniform Earth, expressions in terms of the Neumann and Struve functions are also possible. These are further developed in this paper, resulting in new infinite series expansions, not presented before, for the electric and magnetic fields. An application of the series expansions will remove the need to calculate the standard integral expressions, and performing exact numerical computations will be straightforward.
The Influence of Ion-Acoustic Turbulence on the Electron Acceleration in the Reconnecting Current Sheet

Through solving the single electron equation of motion and the Fokker-Planck equation including the terms of electric field strength and ion-acoustic turbulence, we study the influence of the ion-acoustic wave on the electron acceleration in turbulent reconnecting current sheets. It is shown that the ion-acoustic turbulence which causes plasma heating rather than particle acceleration should be considered. With typical parameter values, the acceleration time scale is around the order of 10(-6) s, the accelerated electrons may have approximately a power-law distribution in the energy range 20 similar to 100 keV and the spectral index is about 3 similar to 10, which is basically consistent with,the observed hard X-ray spectra in solar flares.
Size dependent change of mean square displacement in gold nanocrystals: A molecular dynamics simulation

Thermally activated atomic vibrations significantly decrease the x‐ray diffraction intensities of nanocrystalline powders. Hence their quantification is critical for accurate structural characterization of small nanocrystals by x‐ray diffraction. In this study, atomic vibrations in the form of mean square displacements (MSDs) in 5, 10, 15, 20, and 30 nm diameter spherical gold nanocrystals were computed by molecular dynamics (MD) simulations at room temperature and below. A strong size and temperature dependency of MSD was observed from spherical gold nanocrystals. Moreover, these displacements increased radially from the center of the nanocrystals and reached a maximum at the surface layers due to the presence of undercoordinated surface atoms and their relatively unrestricted motions. High temperature simulations were performed to investigate the evolution of structural stability of nanoparticles with increasing temperature. Surface melting was observed before complete melting of nanocrystals. Results of this work will be useful to understand the effect of nanocrystal size on the amplitude of thermally activated atomic vibrations and their quantification in measured intensities by x‐ray diffraction experiments.
Future Pose Prediction from 3D Human Skeleton Sequence with Surrounding Situation

Human pose prediction is vital for robot applications such as human–robot interaction and autonomous control of robots. Recent prediction methods often use deep learning and are based on a 3D human skeleton sequence to predict future poses. Even if the starting motions of 3D human skeleton sequences are very similar, their future poses will have variety. It makes it difficult to predict future poses only from a given human skeleton sequence. Meanwhile, when carefully observing human motions, we can find that human motions are often affected by objects or other people around the target person. We consider that the presence of surrounding objects is an important clue for the prediction. This paper proposes a method for predicting the future skeleton sequence by incorporating the surrounding situation into the prediction model. The proposed method uses a feature of an image around the target person as the surrounding information. We confirmed the performance improvement of the proposed method through evaluations on publicly available datasets. As a result, the prediction accuracy was improved for object-related and human-related motions.
Identification of Aging and Young Subtypes for Predicting Colorectal Cancer Prognosis and Immunotherapy Responses

Colorectal cancer (CRC) is critically related to aging and severely threatens human lives. To better explore the effects of aging on CRC progression and therapy outcome, a reliable aging subtypes identification of CRC is urgently desired. Here, 28 aging-related genes associated with the CRC prognosis were selected by univariate Cox analyses. Based on these 28 genes, CRC patients were divided into the aging subtype and young subtype by non-negative matrix factorization clustering. Aging subtype and young subtype of CRC were identified with distinct molecular features and clinical prognosis. The aging subtype was characterized by upregulation of senescence-associated secretory phenotype, higher frequencies of TP53 and immune checkpoint molecules, and high sensitivity to protein kinase and angiogenesis inhibitors. Furthermore, 14 genes were selected by LASSO penalized Cox regression analyses for aging-related risk signature construction. The constructed aging risk signature exhibited good prediction and the nomogram showed robust discrimination power over the traditional CRC staging system. In conclusion, this study successfully established aging subtype and young subtype of CRC, which is helpful to identify patients with aging characteristics to evaluate prognosis and treatment outcomes. Introducing aging-based subtypes into clinical concern and patient prognostication provides new opportunities for personalized CRC treatment.
Characterization and Seasonal Modulation of Adenosine A1 Receptors in the Arctic Ground Squirrel Brain

Hibernation is an adaptation that allows animals such as the Arctic ground squirrel (AGS) to survive the absence of food or water during the winter season. Understanding mechanisms of metabolic suppression during hibernation torpor promises new therapies for critical care. The activation of the Adenosine A1 receptor (A1AR) has been shown to be necessary and sufficient for entrance into hibernation with a winter season sensitization to the agonist, but the role of the A1AR in seasonal sensitization is unknown. In the current study, we characterize the A1AR in the forebrain, hippocampus and hypothalamus of summer and torpid AGS. For the first time, we define the pharmacological characteristics of the A1AR agonist, N6-cyclohexyladenosine and the A1AR antagonist dipropylcyclopentylxanthine (DPCPX) in the AGS brain. In addition, we test the hypothesis that increased A1AR agonist efficacy is responsible for sensitization of the A1AR during the torpor season. The resulting 35S-GTPγS binding data indicate an increase in agonist potency during torpor in two out of three brain regions. In addition to 35S-GTPγS binding, [3H]DPCPX saturation and competition assays establish for the first-time pharmacological characteristics for the A1AR agonist, N6-cyclohexyladenosine and the A1AR antagonist dipropylcyclopentylxanthine (DPCPX) in AGS brain.
Vacuum Particle Creation: Analogy with the Bloch Theory in Solid State Physics

A nonperturbative kinetic description of interband tunneling under the action of a strong electric field (dynamical analogue of the Zener effect) is presented. The developed approach is based on the similarity to the Sauter‐Schwinger effect and its dynamical analogue in QED. The kinetic equation for electron‐hole quasiparticle excitations is derived on a dynamical basis in the framework of the oscillator representation. Numerical estimates are made for some simple cases of external fields. Detailed comparisons with the method based on the Bloch equations for electron‐hole systems interacting with a time dependent electric field are performed. The proposed approach is an alternative to the Bloch theory and does not use the dipole approximation. This leads to predictions which differ from the ones based on the Bloch equations, in particular, concerning the frequency dependence of the absorption coefficient (© 2009 WILEY‐VCH Verlag GmbH & Co. KGaA, Weinheim)
Series representation and simulation of multifractional Lévy motions

This paper introduces a method of generating real harmonizable multifractional Lévy motions (RHMLMs). The simulation of these fields is closely related to that of infinitely divisible laws or Lévy processes. In the case where the control measure of the RHMLM is finite, generalized shot-noise series are used. An estimation of the error is also given. Otherwise, the RHMLM X h is split into two independent RHMLMs, X ε,1 and X ε,2. More precisely, X ε,2 is an RHMLM whose control measure is finite. It can then be rewritten as a generalized shot-noise series. The asymptotic behaviour of X ε,1 as ε → 0+ is further elaborated. Sufficient conditions to approximate X ε,1 by a multifractional Brownian motion are given. The error rate in terms of Berry-Esseen bounds is then discussed. Finally, some examples of simulation are given.
Emergent fractional quantum Hall effect at even denominator ν = 3/2 in a triple quantum well in tilted magnetic fields

This work reports on the experimental observation of the even-denominator state ν = 3/2 in a trilayer electron system in tilted magnetic fields. The ν = 3/2 state demonstrates a strong minimum in longitudinal resistance and is accompanied by a plateau in Hall resistance in a narrow range of tilt angles.