Miracle-dz/UniFAR-FTUs huggingface dataset:
An Efficient Characterization of a Family of Hyperbent Functions

Charpin and Gong recently characterized a large class of hyperbent functions defined on fields of order 2n, which include the well-known monomial functions with the Dillon exponent as a special case. We give a reformulation of the Charpin-Gong criterion in terms of the number of rational points on certain hyperelliptic curves. We present two applications of our result: The time needed to check the hyperbentness of a specific function is now polynomial in n , and hyperbent functions with subfield coefficients can be constructed.
Revolution oder Evolution – Neue Trends in der Business Intelligence

Um im Wettbewerb bestehen zu können, ist es für industrielle Unternehmen von zentraler Bedeutung, die Auswirkungen produktbezogener Entscheidungen möglichst zum Zeitpunkt der Entscheidung antizipieren zu können. Betriebswirtschaftliche Analysen müssen dazu neben Daten aus transaktionsorientierten und betriebswirtschaftlichen Systemen auch Produkteigenschaften beschreibende Daten des technischen Bereichs wie der Konstruktion berücksichtigen. Gegenwärtig existiert hier jedoch keine ausreichende Integration. Dieser Beitrag thematisiert die Ausgangssituation und zeigt auf, wie Daten aus den verschiedenen Systemen der Bereiche in einem produktorientierten Datawarehouse zusammengeführt und für Auswertungen entlang des gesamten Produktlebenszyklus verfügbar gemacht werden können, um dadurch die Notwendigkeit eines Konzepts für ETLProzesse zur Befüllung von produktorientierten Datawarehouses als Ziel des dargestellten Forschungsvorhabens bzw. den Forschungsbedarf abzuleiten.
Empirical evaluation of hybrid filtering: An approach for speech enhancement

The speech enhancement technique used in this paper improves the quality of noisy speech. Speech is corrupted by different background noises hence quality of speech is degraded. The approach used in this paper enhances quality of speech using wiener filter. The combination of two dimensional and one dimensional wiener filter named hybrid wiener filter improves quality of noisy speech. The approach shown in this paper for speech enhancement shows that speech enhancement is transform dependent. This is presented in this paper by applying hybrid filter to transformed speech using DFT, DCT and DWT. The validation that hybrid filtering and transform domain dependency is presented using different objective quality measures.
The right shift theory of a genetic balanced polymorphism for cerebral dominance and cognitive processing. Commentaries. Author's reply

The right shift (RS) theory of handedness (Annett, 1972, 1985) suggested that the high prevalence of human right-handedness and left hemisphere specialization for speech is due to a single factor which induces the typical pattern of cerebral specialization and incidentally displaces a chance distribution of manual asymmetry toward dextrality. The factor could be a single gene (rs+). An estimate of genotype frequencies based on the percentage of right hemisphere speakers suggested a genetic balanced polymorphism with heterozygote advantage. Studies of actual hand skill suggest that strong dextrality depends on a process which induces left hand weakness, probably associated with impairment of right hemisphere function. Non gene-carriers (rs-genotypes) avoid right hemisphere handicap but are at risk for the development of speech and speech dependent language processes. People with specific deficits of phonological processing have reduced bias to dextrality, as expected if they lack the rs+ gene. The presence of the rs+ gene is associated with poorer spatial ability and this is true for left-handers as well as right-handers. The higher proportion of nonright-handers among mathematicians and other talented groups may be due to the absence of rs++ genotypes, rather than to an intrinsic advantage for left-handers. Evidence for heterozygote advantage has been found in studies of educational achievement, especially in reading. Poor readers are more prevalent at both extremes of the laterality distribution. A critical test of the balanced polymorphism hypothesis asked whether a double dissociation exists between people with specific deficits of phonological versus visual memory for words, and reduced versus strong bias to dextrality respectively. Evidence for this double dissociation was found in school and university samples. Applying the model to dyslexia, children with specific reading difficulties classified for presence versus absence of poor phonology were found to differ for handedness as expected if the former are less dextral and the latter more dextral than controls. These findings are not due to pathology, but they are associated with differences in the handedness of relatives, as expected by the RS model. Criticisms of the balanced polymorphism model are shown to be ill-founded. Questions of interpretation of the theory are considered and needs for further research are indicated.
V-src kinase shifts the cadherin-based cell adhesion from the strong to the weak state and beta catenin is not required for the shift

The elevation of tyrosine phosphorylation level is thought to induce the dysfunction of cadherin through the tyrosine phosphorylation of beta catenin. We evaluated this assumption using two cell lines. First, using temperature-sensitive v-src-transfected MDCK cells, we analyzed the modulation of cadherin-based cell adhesion by tyrosine phosphorylation. Cell aggregation and dissociation assays at nonpermissive and permissive temperatures indicated that elevation of the tyrosine phosphorylation does not totally affect the cell adhesion ability of cadherin but shifts it from a strong to a weak state. The tyrosine phosphorylation levels of beta catenin, ZO-1, ERM (ezrin/radixin/moesin), but not alpha catenin, vinculin, and alpha- actinin, were elevated in the weak state. To evaluate the involvement of the tyrosine phosphorylation of beta catenin in this shift of cadherin-based cell adhesion, we introduced v-src kinase into L fibroblasts expressing the cadherin-alpha catenin fusion protein, in which beta catenin is not involved in cell adhesion. The introduction of v-src kinase in these cells shifted their adhesion from a strong to a weak state. These findings indicated that the tyrosine phosphorylation of beta catenin is not required for the strong-to-weak state shift of cadherin-based cell adhesion, but that the tyrosine phosphorylation of other junctional proteins, ERM, ZO-1 or unidentified proteins is involved.
Bidirectional Work–Family Enrichment Mediates The Relationship Between Family-Supportive Supervisor Behaviors and Work Engagement

We applied the resource–gain–development perspective to test a theoretical model in which family-supportive supervisor behaviors (FSSB) were expected to predict work engagement through the mediator of bidirectional work–family enrichment (work–family enrichment and family–work enrichment) over time. Using a 2-wave survey conducted over a 5-month interval, we collected data from 268 full-time employees of Chinese industries. When controlling for perceived general supervisor support and perceived organizational support at Time 1, the hierarchical regression analysis results revealed that FSSB at Time 1 increased bidirectional work–family enrichment and work engagement at Time 2. In addition, bidirectional work–family enrichment was found to fully mediate the relationship between FSSB and work engagement. Theoretical contributions and managerial implications are discussed.
Connectivity reliability analysis of different scale BA networks

Large scale networks, which are complex systems with huge number of nodes and links, are difficult to evaluate reliability with the existing theory of algorithms, simulation and test methods because of high complexity. In practice, a simplified version of network is always developed as the basis for the evaluation in order to greatly decrease the complexity of the analysis. Therefore, it is of great importance to search for the potential influences on reliability brought by the network simplification. BA network is a classic scale-free network model, which is best suitable to describe the network topology of many practical complex engineering networks. However, the effect on connectivity reliability of BA network brought by downsizing and reducing the number of nodes for simplification is still not clear. In this paper, a reliability simulation test is designed based on the network model built up to analyze the changing of network connectivity rate as the result of the physical failure of BA network nodes. Simulation results demonstrate the conclusion that the connectivity reliability of BA networks with different sizes shares some similarities, which can be regarded as the basis for network simplification in the scale-free network reliability analysis.
Diagnosis of toxoplasmosis after allogeneic stem cell transplantation: results of DNA detection and serological techniques.

BACKGROUND The biological diagnosis of toxoplasmosis after allogeneic hematopoietic stem cell transplantation (HSCT) is based on the detection of Toxoplasma gondii DNA in blood specimens or other samples. Serological testing is used mainly to define the immunity status of the patient before HSCT. The aim of our study was to examine the performance of polymerase chain reaction (PCR) and serological techniques in the diagnosis of toxoplasmosis after HSCT. METHODS Seventy patients underwent allogeneic HSCT from September 2004 through September 2006. DNA was detected by PCR, and immunoglobulin G and immunoglobulin M were detected by enzyme-linked immunosorbent assay. RESULTS The results of immunoglobulin G detection before allogeneic HSCT were positive in 40 (57.1%) of the patients and negative in 30 (42.9%). After HSCT, 57 patients (81.4%) had test results that were negative for immunoglobulin M and had negative results of DNA detection, without toxoplasmosis infection. Four patients (5.7%) had at least 4 samples with positive PCR results and/or test results positive for immunoglobulin M against T. gondii; toxoplasmosis was then confirmed by clinical symptoms. Nine patients (12.9%) with positive PCR results and 1 or 2 samples with test results negative for immunoglobulin M were considered to have asymptomatic T. gondii infection. Reactivation of latent infection was the cause of toxoplasmosis in 3 of the 4 patients, and toxoplasmosis occurred as a primary infection in 1 patient. The detection of specific anti-T. gondii immunoglobulin M was the only biological evidence of toxoplasmosis in 2 patients, and samples were positive for immunoglobulin M before PCR was performed in 1 patient. CONCLUSIONS Thus, after HSCT, all patients were at risk for toxoplasmosis; all patients who receive HSCTs should be followed up with biological testing that combines PCR and serological techniques.
Effect of oxytocin-supplemented semen on fertility of sows bred by intrauterine insemination

Methods: During September 2002, mixed parity sows on two commercial farrow-towean units (3000 and 1500 PIC sows) were inseminated at their first estrus after weaning (weaned sows; n = 442) or at a repeat estrus following a previous failure to successfully conceive (repeat sows; n = 100), using either a cervical (199 sows) or intrauterine AI catheter. For sows inseminated using the intrauterine catheter, the semen did (172 sows), or did not (171 sows), contain 5 IU oxytocin. Semen age at insemination varied from 2 to 8 days.
Cloning and Sequence Analysis of the Promoter Region of the MRP Gene of HL 60 Cells Isolated for Resistance to Adriamyein 1

Non-P-glycoprotein multidrug resistance of HL60/ADR cells appears to be related to overexpression of the MRP gene. Recent studies suggest that this gene may play an important role in a new form of cell resistance to certain chemotherapeutic agents. To examine mechanisms regulating transcriptional activity of this gene, a 2.2-kilobase 5'-flanking sequence of MRP has been isolated from a genomic library prepared from HL60/ADR cells. The 2.2-kilobase DNA fragment linked to the chloramphenicol acetyltransferase (CAT) gene in a reporter plasmid was found to be capable of driving expression of this gene in transient transfection exper iments. This DNA containing promoter activity has been sequenced in its entirety and found to contain multiple putative regulatory sites. A series of deletion mutants linked to the CA T reporter gene was used to examine functional domains of the 2.2-kilobase sequence. The results suggest that promoter activity is contained in nucleotides -91 to +103 in a GC-rich region of the MRP genome. Promoter activity contained within this se quence, however, is modulated by both positive and negative regulatory elements. Certain of the regulatory sites contain consensus sequences for positive and negative regulatory elements which have been found in the promoter regions of other genes. Primer extension analysis indicates the presence of multiple major transcriptional start sites from the MRP promoter. Sequence analysis of MHI' genomic and complementary DNAs has defined the exon/intron boundaries and the organization of a portion of the 5 '-end region of the MRP genome. The results of these studies thus provide new insight in site-specific domains which may function in the regulation of MRP gene expression.
The Art of Entrainment

The circadian system actively synchronizes the temporal sequence of biological functions with the environment. The oscillatory behavior of the system ensures that entrainment is not passive or driven and therefore allows for great plasticity and adaptive potential. With the tools at hand, we now can concentrate on the most important circadian question: How is the complex task of entrainment achieved by anatomical, cellular, and molecular components? Understanding entrainment is equal to understanding the circadian system. The results of this basic research will help us to understand temporal ecology and will allow us to improve conditions for humans in industrialized societies.
Ontological Metaphor in Economic News Reports: A Pragmatic Approach

With the development of the world of economy, economic reports in journals, magazines or news websites have become an essential part of daily life. Economic news demonstrates rigid and abstract concepts and meanings. It is a truism that clarity is as important as accuracy. However, writers of such news should not stick only to formal language. Their words would sound boring. To keep the audience interested, figurative language is manipulated. One rhetorical device frequently used in this genre is metaphor. It sheds some colorings on the rigid language of finance and economics. Thus, it deserves an investigatory research work. This paper sets itself the task of exploring one particular kind of metaphor, i.e. ontological metaphor. It aims at pragmatically exploring its kinds that can be possibly utilized in economic news reports. This involves specifying the most prevalent kind of ontological metaphor. It is hypothesized that in such a kind of news, ontological metaphorical uses show different manifestations like metonymy, personification or hyperbole. However, it is assumed that metonymy is the most prevailing one. The data chosen for the analysis are randomly taken from different economic websites and are analyzed by means of a model developed by this study. The analysis is quantitatively supported by a statistical analysis conducted via the percentage equation. The most significant findings of the analyses vindicate the two hypotheses set above. This paper is hoped to be valuable to pragmaticians and economic news writers or journalists who should be aware of such rhetorical devices to make use of them.
Learning Temporal Tagging Behaviour

Social networking services, such as Facebook, Google+, and Twitter are commonly used to share relevant Web documents with a peer group. By sharing a document with her peers, a user recommends the content for others and annotates it with a short description text. This short description yield many chances for text summarization and categorization. Because today's social networking platforms are real-time media, the sharing behaviour is subject to many temporal effects, i.e., current events, breaking news, and trending topics. In this paper, we focus on time-dependent hashtag usage of the Twitter community to annotate shared Web-text documents. We introduce a framework for time-dependent hashtag recommendation models and introduce two content-based models. Finally, we evaluate the introduced models with respect to recommendation quality based on a Twitter-dataset consisting of links to Web documents that were aligned with hashtags.
"Kann es sein, dass ich das Beginndatum falsch erfasst habe?" Reactive Dependent Interviewing bei der Erhebung von Ausbildungs- und Erwerbsverläufen junger Erwachsener

One of the challenges in the collection of life course-data in panel-design-surveys is to guarantee overall consistency of the data from different annual surveys. “Dependent Interviewing” is one possibility to reduce these difficulties, by drawing on data collected at previous waves to phrase questions or direct respondents through the Survey-instrument. For the eighth wave of the longitudinal survey TREE (Transitions from Education to Employment) forms of “Reactive Dependent Interviewing” were used to ensure the connection to existing episodes of previous waves. Based on findings from cognitive psychology, further modules of plausibilisation were integrated in the CATI-instrument: a visual presentation of life course-data on the screen for interviewers and consistency checks for gaps – periods without activity – as well as overlapping activities. This article presents results of the first analysis of survey raw data and describes the application and usefulness of the developed CATI-tools.
Enhanced Thermal Stability and Hydrolytic Ability of Bacillus subtilis Aminopeptidase by Removing the Thermal Sensitive Domain in the Non-Catalytic Region

Besides the catalytic ability, many enzymes contain conserved domains to perform some other physiological functions. However, sometimes these conserved domains were unnecessary or even detrimental to the catalytic process for industrial application of the enzymes. In this study, based on homology modeling and molecular dynamics simulations, we found that Bacillus subtilis aminopeptidase contained a thermal sensitive domain (protease-associated domain) in the non-catalytic region, and predicted that deletion of this flexible domain can enhance the structure stability. This prediction was then verified by the deletion of protease-associated domain from the wild-type enzyme. The thermal stability analysis showed that deletion of this domain improved the T50 (the temperature required to reduce initial activity by 50% in 30 min) of the enzyme from 71°C to 77°C. The melting temperature (Tm) of the enzyme also increased, which was measured by thermal denaturation experiments using circular dichroism spectroscopy. Further studies indicated that this deletion did not affect the activity and specificity of the enzyme toward aminoacyl-p-nitroanilines, but improved its hydrolytic ability toward a 12-aa-long peptide (LKRLKRFLKRLK) and soybean protein. These findings suggested the possibility of a simple technique for enzyme modification and the artificial enzyme obtained here was more suitable for the protein hydrolysis in food industry than the wild-type enzyme.
Optimal full matching for survival outcomes: a method that merits more widespread use

Matching on the propensity score is a commonly used analytic method for estimating the effects of treatments on outcomes. Commonly used propensity score matching methods include nearest neighbor matching and nearest neighbor caliper matching. Rosenbaum (1991) proposed an optimal full matching approach, in which matched strata are formed consisting of either one treated subject and at least one control subject or one control subject and at least one treated subject. Full matching has been used rarely in the applied literature. Furthermore, its performance for use with survival outcomes has not been rigorously evaluated. We propose a method to use full matching to estimate the effect of treatment on the hazard of the occurrence of the outcome. An extensive set of Monte Carlo simulations were conducted to examine the performance of optimal full matching with survival analysis. Its performance was compared with that of nearest neighbor matching, nearest neighbor caliper matching, and inverse probability of treatment weighting using the propensity score. Full matching has superior performance compared with that of the two other matching algorithms and had comparable performance with that of inverse probability of treatment weighting using the propensity score. We illustrate the application of full matching with survival outcomes to estimate the effect of statin prescribing at hospital discharge on the hazard of post‐discharge mortality in a large cohort of patients who were discharged from hospital with a diagnosis of acute myocardial infarction. Optimal full matching merits more widespread adoption in medical and epidemiological research. © 2015 The Authors. Statistics in Medicine Published by John Wiley & Sons Ltd.
Integrating Model-Based Testing in Model-Driven Web Engineering

Much of the research into testing model-driven systems has focused on checking the models used to drive code generation, and testing the transformations that are used. This is predicated upon the use of full code generation. However, much of the model-driven system development used in practice is based on the use of partial code generation, where the developer implements sections of the system by modifying or adding to the generated code. In these situations, it is important to test for problems in or caused by this manually modified code. In this paper, we present a pragmatic approach to testing model-driven systems based on partial code generation. Our approach uses model-based testing techniques based on reuse of development models to drive test case generation.
Application of eGaN FETs for highly efficient Radio Frequency Power Amplifier

In this paper, application of new technological solution for power switches based on Gallium Nitride (GaN) in Envelope Amplifier for Radio Frequency Power Amplifier is proposed. The goal of this application is the efficiency enhancement at high switching frequency, due to superior conductivity and switching characteristics of enhancement mode GaN FETs over Si devices. Experimental results provided comparison between the performance of GaN FETs on one hand and standard Si MOSFETs and LDMOS transistors on the other. Advantages of GaN devices were experimentally verified as well as the operating conditions (regarding the output power and switching frequency) where these advantages exist.