Miracle-dz/UniFAR-FTUs huggingface dataset:
Different classification techniques considering brain computer interface applications

In this work the application of different machine learning techniques for classification of mental tasks from electroencephalograph (EEG) signals is investigated. The main application for this research is the improvement of brain computer interface (BCI) systems. For this purpose, Bayesian graphical network, neural network, Bayesian quadratic, Fisher linear and hidden Markov model classifiers are applied to two known EEG datasets in the BCI field. The Bayesian network classifier is used for the first time in this work for classification of EEG signals. The Bayesian network appeared to have a significant accuracy and more consistent classification compared to the other four methods. In addition to classical correct classification accuracy criteria, the mutual information is also used to compare the classification results with other BCI groups.
The Prognostic Importance of Isolated Tumor Cell Clusters and Micrometastases in Sentinel Lymph Nodes

This chapter explores the prognostic impact of nodal metastases and in particular considers the importance of sentinel lymph node biopsy in the context of enhanced detection of micrometastases and isolated tumor cell clusters (ITC). Lymph node metastases, specifically axillary nodal metastases, are considered to be one of the most important factors stratifying between good and bad prognosis breast cancers. Historically, the emphasis has been placed on the presence or absence of nodal disease. This dichotomous stratification was challenged as accumulated clinical data indicated the total number of involved lymph nodes had prognostic significance (1). Further, pathological data indicated the size of the metastatic focus had prognostic significance (2). Acknowledging these observations, the sixth edition AJCC and UICC staging manuals formally incorporated semiquantitative nodal tumor burden into the stage and substage groupings; both the number of involved lymph nodes and the size of the metastatic foci influence overall stage (3–5). This principle is consistent with quantifying primary tumor burden, the other mainstay of tumor prognosis and staging. Tumor burden has stood the test of time as a valuable prognostic factor; however, it is a relatively crude measure when one considers that modern investigations of tumor biology can identify defects in isolated biochemical regulatory pathways. Why then in a book on translational therapeutic strategies for breast cancer are we interested in a factor as crude as nodal tumor burden? The answer to this question rests on the foundational observation that a focus of tumor in a lymph node, a metastasis in the traditional sense, represents the demonstrated capacity of a tumor to proliferate, invade, travel to a new location, proliferate in that location, and potentially spawn further metastatic foci. The critical question is when does a discovered nodal tumor deposit have clinical significance? This is not a simple question when considering micrometastases. The discussion in this chapter focuses on minimal tumor burden and how it is detected in sentinel nodes. The underlying thesis is that micrometastases and ITC clusters in lymph nodes must have less prognostic significance than macrometastases.
Getting the most out of a international diffusion model through evolutionary programming

The use of an evolutionary programming approach called differential evolution for configuring a simulation model is described. Designed to simulate the international diffusion of technology, the simulation model has eight bounded configuration parameters, six continuous and two discrete. The performance of the model is measured using the non-parametric rank order correlation of simulated versus actual year of national adoption of the technology in question. Results show that, with one exception, the best performing configurations identified for simulating the international diffusion of nine technologies compare favorably with a range of published works on diffusion and specifically the international diffusion process. The comparison provides some validation for the model and for the utility of differential evolution as a method for the heuristic search of simulation parameters. The paper can be viewed as a case study in differential evolution applied to finding good quality configurations of a simulation model.
ardiac esynchronization Therapy 101 f It ’ s Not Late , acing It Early Won ’ t Help * nne

ardiac resynchronization therapy (CRT) is an effective reatment for heart failure (HF) for patients who still have ignificant symptoms despite optimal medical therapy. any patients with HF have interventricular and intravenricular conduction delays that cause delayed activation of he lateral wall of the left ventricle (LV). This delayed ctivation leads to ventricular dyssynchrony, which comproises diastolic filling time, decreases LV ejection fraction, nd worsens mitral regurgitation and ventricular dilation. y placing a lead through the coronary sinus to a lateral or osterolateral branch, the LV can be paced simultaneously r near-simultaneously with pacing from the right ventricle, eading to resynchronization of the ventricles. New York eart Association functional class, exercise tolerance, qualty of life, and LV ejection fraction have all been shown to mprove with CRT (1–4).
Pedestrian Fall Action Detection and Alarm in Video Surveillance

In this paper we introduce a novel method to detect and alarm pedestrian fall action in video surveillance by using frame difference method and pedestrians marker frame. Firstly, we used the fixed camera to capture video image information, and applied the morphological erosion and dilation method to reduce the noises. Then combined the frame difference method and the background difference method to mark the target contour, and analyzed the contour information to fix the pedestrian location. Finally, by analyzing the motion position and trajectory of the centroid of pedestrian and analyzing length-to-width ratio of pedestrians marker frame and residence time to detect pedestrian fall action and other abnormal motions, and give the alarm in time. The experiments show that the proposed method captures the pedestrian fall action successfully.
Warm-up in a Virtual Reality Environment Improves Performance in the Operating Room

Objective:To assess the impact of warm-up on laparoscopic performance in the operating room (OR). Background:Implementation of simulation-based training into clinical practice remains limited despite evidence to show that the improvement in skills is transferred to the OR. The aim of this study was to evaluate the impact of a short virtual reality warm-up training program on laparoscopic performance in the OP. Methods:Sixteen Laparoscopic Cholecystectomies were performed by 8 surgeons in the OR. Participants were randomized to a group which received a preprocedure warm-up using a virtual reality simulator and no warm-up group. After the initial laparoscopic cholecystectomy all surgeons served as their own controls by performing another procedure with or without preoperative warm-up. All OR procedures were videotaped and assessed by 2 independent observers using the generic OSATS global rating scale (from 7 to 35). Results:There was significantly better surgical performance on the laparoscopic Cholecystectomy following preoperative warm-up, median 28.5 (range = 18.5–32.0) versus median 19.25 (range = 15–31.5), P = 0.042. The results demonstrated excellent reliability of the assessment tool used (Cronbach's &agr; = 0.92). Conclusion:This study showed a significant beneficial impact of warm-up on laparoscopic performance in the OP. The suggested program is short, easy to perform, and therefore realistic to implement in the daily life in a busy surgical department. This will potentially improve the procedural outcome and contribute to improved patient safety and better utilization of OR resources.
A real time processing and streaming of wireless network data using Storm

Growth of the Internet, Lead to Cloud Computing, Mobile Network and Internet of Things increasing rapidly, big data is becoming a hot-spot in recent years. Data generated from many sources made huge demand for storing, managing, processing and querying on various stream. This gives rise to data processing in our daily life such as mobile devices, RFID and Wireless sensors, which aims at dealing with billions of users interactive data. At real time processing is intently needed integrated system. An entire system is built on one such application Storm, associated with Sql Stream. In this survey use this static data stream and some logs stream and also click stream to show some basic result. To ensure the practical applicability and high efficiency, A Simulation System is established and shown acceptable performance in various expressions using data sheet. It proved that data analysis system for stream and real time processing based on storm can be used in various computing environment.
Sex ratio effects on reproductive strategies in humans

Characterizations of coy females and ardent males are rooted in models of sexual selection that are increasingly outdated. Evolutionary feedbacks can strongly influence the sex roles and subsequent patterns of sex differentiated investment in mating effort, with a key component being the adult sex ratio (ASR). Using data from eight Makushi communities of southern Guyana, characterized by varying ASRs contingent on migration, we show that even within a single ethnic group, male mating effort varies in predictable ways with the ASR. At male-biased sex ratios, men's and women's investment in mating effort are indistinguishable; only when men are in the minority are they more inclined towards short-term, low investment relationships than women. Our results support the behavioural ecological tenet that reproductive strategies are predictable and contingent on varying situational factors.
Tagging Heterogeneous Evaluation Corpora for Opinionated Tasks

Opinion retrieval aims to tell if a document is positive, neutral or negative on a given topic. Opinion extraction further identifies the supportive and the non-supportive evidence of a document. To evaluate the performance of technologies for opinionated tasks, a suitable corpus is necessary. This paper defines the annotations for opinionated materials. Heterogeneous experimental materials are annotated, and the agreements among annotators are analyzed. How human can monitor opinions of the whole is also examined. The corpus can be employed to opinion extraction, opinion summarization, opinion tracking and opinionated question answering.
Multiple functions encoded by the N-terminal PAT domain of adipophilin

Adipophilin (ADPH), a member of the perilipin family of cytoplasmic lipid droplet (CLD)-binding proteins, is crucially dependent on triglyceride synthesis for stability. We have used cell lines expressing full-length or N-terminally modified forms of ADPH to investigate the role of the N-terminus in regulating ADPH stability and interactions with CLD. Full-length ADPH was unstable and could not be detected on CLDs unless cultures were incubated with oleic acid (OA) to stimulate triglyceride synthesis, or were treated with MG132 to block proteasomal degradation. By contrast, ADPH lacking amino acids 1-89 (Δ 2,3 ADPH), or N-terminally GFP-tagged full-length ADPH, was stable in the absence of OA or MG132, as was the closely related protein TIP47. However, none of these proteins localized to CLDs unless OA was added to the culture medium. Furthermore, immunofluorescence analysis showed that TIP47 localization to CLDs was prevented by full-length ADPH, but not by Δ 2,3 ADPH. These results suggest that the N-terminal region of ADPH mediates proteasomal degradation and access of TIP47 to the CLD surface and possibly contributes to CLD stability. Chimeras of ADPH and TIP47, generated by swapping their N- and C-terminal halves, showed that these properties are specific to ADPH.
Verification of Description Logic Knowledge and Action Bases

We introduce description logic (DL) Knowledge and Action Bases (KAB), a mechanism that provides both a semantically rich representation of the information on the domain of interest in terms of a DL KB and a set of actions to change such information over time, possibly introducing new objects. We resort to a variant of DL-Lite where UNA is not enforced and where equality between objects may be asserted and inferred. Actions are specified as sets of conditional effects, where conditions are based on epistemic queries over the KB (TBox and ABox), and effects are expressed in terms of new ABoxes. We address the verification of temporal properties expressed in a variant of first-order μ-calculus where a controlled form of quantification across states is allowed. Notably, we show decidability of verification, under a suitable restriction inspired by the notion of weak acyclicity in data exchange.
The SH2 and SH3 domains of pp60src direct stable association with tyrosine phosphorylated proteins p130 and p110.

Transformation of chicken embryo cells with the tyrosine kinase oncogene src results in the tyrosine phosphorylation of numerous cellular proteins. We have recently generated monoclonal antibodies to individual tyrosine phosphorylated cellular src substrates, several of which are directed to the phosphotyrosine‐containing proteins p130 and p110. These proteins form stable complexes with activated variants of pp60src. Mutagenesis of the src homology domains (SH2 and SH3) of activated pp60src resulted in src variants with altered association with p130 and p110. Analysis of these variants showed that the SH3 domain was required for association of p110, while the SH2 domain contained residues necessary for the formation of the ternary complex involving p130, p110 and pp60src. Both the tyrosine phosphorylation status and pp60src association of p130 and p110 appeared to correlate, in part, with the extent of cell transformation. Biochemical analysis demonstrated that p130 and p110 were substrates of both serine/threonine and tyrosine kinases. In addition, p130 was redistributed from the nucleus to cellular membranes upon src transformation, whereas p110, which normally colocalized with cytoskeletal elements, was observed in adhesion plaques (podosomes) in src transformed cells. These data indicate that tyrosine phosphorylation of two different phosphoproteins may play a role during src transformation either by directing their interaction with pp60src, by redirecting subcellular distribution or both.
K-exponential Stabilization of Uncertain High-order Nonholonomic Chained Systems

In this paper, we address the problem of K-exponential stabilization for a class of uncertain high-order nonholonomic chained systems. This particular class of nonlinear systems is an extension of a nonholonomic system in chained form that has received considerable attention in the past few years. Using input/state scaling and integrator backstepping methods, we construct noncontinuous feedback law and give out the switching strategy, such that the related closed-loop systems K-exponential stable.
High order integral sliding mode control with gain adaptation

In this paper, an adaptive integral sliding mode is proposed. The main interest of gain adaptation is the reduction of the chattering and the possibility to control uncertain nonlinear systems whose the uncertainties have unknown bounds. The proposed control approach consists in using dynamically adapted control gain that ensure the establishment, in a finite time, of a real high order sliding mode. The control is applied by simulation to an academic example to evaluate its efficiency.
Incremental Record Linkage

Record linkage clusters records such that each cluster corresponds to a single distinct real-world entity. It is a crucial step in data cleaning and data integration. In the big data era, the velocity of data updates is often high, quickly making previous linkage results obsolete. This paper presents an end-to-end framework that can incrementally and efficiently update linkage results when data updates arrive. Our algorithms not only allow merging records in the updates with existing clusters, but also allow leveraging new evidence from the updates to fix previous linkage errors. Experimental results on three real and synthetic data sets show that our algorithms can significantly reduce linkage time without sacrificing linkage quality.
Antimicrobial Activity of a Novel Catheter Lock Solution

ABSTRACT Intravascular catheter-associated bloodstream infections significantly increase rates of morbidity and hospital costs. Microbial colonization and development of biofilms, which are known to be recalcitrant to antibiotic therapy, often lead to the loss of otherwise patent vascular access systems. We evaluated a new taurolidine- and citrate-based catheter lock solution (Neutrolin; Biolink Corporation, Norwell, Mass.) for its activity against planktonic microbes, antimicrobial activity in a catheter model, and biofilm eradication activity. In studies of planktonic microbes, after 24 h of contact, 675 mg of taurolidine-citrate solution per liter caused >99% reductions in the initial counts of Staphylococcus aureus, Staphylococcus epidermidis, Pseudomonas aeruginosa, and Entercoccus faecalis. A solution of 13,500 mg/liter was cidal for Candida albicans. Ports and attached catheters inoculated with 50 to 600 CFU of these bloodstream isolates per ml were locked with heparin or the taurolidine-citrate solution. After 72 h, there was no growth in the taurolidine-citrate-treated devices but the heparin-treated devices exhibited growth in the range of 6 × 102 to 5 × 106 CFU/ml. Biofilms were developed on silicone disks in modified Robbins devices with broth containing 6% serum (initial counts, 106 to 108 CFU/cm2). The axenic biofilms were treated for 24 h with taurolidine-citrate or heparin. Taurolidine-citrate exposure resulted in a median reduction of 4.8 logs, whereas heparin treatment resulted in a median reduction of 1.7 logs (P < 0.01). No significant differences in the effects of the two treatments against P. aeruginosa and C. albicans were observed. These findings suggest that taurolidine-citrate is a promising combination agent for the prevention and treatment of intravascular catheter-related infections.
Physical Layer Network Coding and Precoding for the Two-Way Relay Channel in Cellular Systems

In this paper, we study the application of physical layer network coding to the joint design of uplink and downlink transmissions, where the base station and the relay have multiple antennas, and all mobile stations only have a single antenna. A new network coding transmission protocol is proposed, where uplink and downlink transmissions can be accomplished within two time slots. Since each single antenna user has poor receive capability, precoding at the base station and relay has been carefully designed to ensure that co-channel interference can be removed completely. Explicit analytic results have been developed to demonstrate that the multiplexing gain achieved by the proposed transmission protocol is , much better than existing time sharing schemes. To further increase the achievable diversity gain, two variations of the proposed transmission protocols have also been proposed when there are multiple relays and the number of the antennas at the base station and relay is increased. Monte-Carlo simulation results have also been provided to demonstrate the performance of the proposed network coded transmission protocol.
Urinary Excretion of C5b-9 in Severe Preeclampsia: Tipping the Balance of Complement Activation in Pregnancy

The complement cascade is activated in normal pregnancy, and excessive complement activation propagates the systemic inflammatory response in severe preeclampsia. Consequently, biomarkers of complement dysregulation may be useful for prediction or treatment of disease. Because renal damage with proteinuria is a characteristic pathological feature of preeclampsia, we hypothesized that complement markers in urine, rather than plasma, could better reflect complement dysregulation in disease. To investigate this, we performed a case–control study of pregnant women, enrolling 25 cases with severe preeclampsia, 25 controls with chronic hypertension, and 25 healthy controls without hypertension matched by gestational age and parity. Subjects were recruited from the Brigham and Women’s Hospital from March 2012 to March 2013. Urine and blood samples were collected on the day of enrollment, with complement activation (C3a, C5a, and C5b-9) measured by ELISA. Severe preeclampsia was associated with marked elevations in urinary C5b-9 (median [interquartile range], 4.3 [1.2–15.1] ng/mL) relative to subjects with chronic hypertension (0 [0–0]) and healthy controls (0 [0–0]; P<0.0001). Urinary excretion of C5b-9 was detected in 96% of cases with severe preeclampsia, 12% of controls with chronic hypertension, and 8% of healthy controls. Cases were also notable for significantly greater urinary excretion of C3a and C5a. Plasma levels of C5a and C5b-9, but not C3a, were increased in the cases with severe preeclampsia compared with healthy controls; however, they did not distinguish preeclampsia from chronic hypertension, supporting our hypothesis that complement markers in urine, rather than plasma, better reflect complement dysregulation. Complement inhibition is an intriguing treatment option for patients with severe preeclampsia.
Improvement of computer network transmission by packing and compression agent technology

In this paper, algorithms which could improve the transmission band for computer networks has been presented. The paper presents the idea and implementation of a mobile agent which could the improve transmission band in a computer network, especially for HTTP files. As a result, the number of transmitted packets (frames) has been reduced several times and transmission efficiency has been improved.
The Relationship between Mothers' Knowledge of Child Development and the Age at Which They Recognize the Special Needs of Their Child.

Noting that early intervention can be an effective method to help children who have special needs and their parents, this study explored the relationship between a mother's knowledge of development and the age at which she recognizes her child's special needs. The second portion of the Knowledge of Infant Development Inventory was used to quantify the mothers' knowledge of child development. Separate questionnaires were developed to address demographic information and the mothers' own personal experiences. Mothers whose children attended local early intervention and preschool programs were asked to volunteer to complete the questionnaires. Analysis of responses found no relationship between the mothers' knowledge of child development and the age at which they recognized their children's special needs. A high significant positive relationship was found between the age at which the mothers noticed their children's special needs and the age at which they sought help. (Contains the Knowledge of Infant Development Inventory, a questionnaire, and 24 references.) (HTH) Reproductions supplied by EDRS are the best that can be made from the ori inal document. THE RELATIONSHIP BETWEEN MOTHERS' KNOWLEDGE OF CHILD DEVELOPMENT AND THE AGE AT WHICH THEY RECOGNIZE THE SPECIAL NEEDS OF THEIR CHILD