Miracle-dz/UniFAR-FTUs huggingface dataset:
STOCHASTIC PARSING AND EVOLUTIONARY ALGORITHMS

This article aims to show the effectiveness of evolutionary algorithms in automatically parsing sentences of real texts. Parsing methods based on complete search techniques are limited by the exponential increase of the size of the search space with the size of the grammar and the length of the sentences to be parsed. Approximated methods, such as evolutionary algorithms, can provide approximate results, adequate to deal with the indeterminism that ambiguity introduces in natural language processing. This work investigates different alternatives to implement an evolutionary bottom-up parser. Different genetic operators have been considered and evaluated. We focus on statistical parsing models to establish preferences among different parses. It is not our aim to propose a new statistical model for parsing but a new algorithm to perform the parsing once the model has been defined. The training data are extracted from syntactically annotated corpora (treebanks) which provide sets of lexical and syntactic tags as well as the grammar in which the parsing is based. We have tested the system with two corpora: Susanne and Penn Treebank, obtaining very encouraging results.
Diuretic renography with the addition of quantitative gravity-assisted drainage in infants and children.

UNLABELLED The aim of this study was to evaluate the use of quantitative gravity-assisted drainage (GAD) using >50% residual activity as an indicator to confirm obstruction in diuretic renography in the investigation of hydronephrosis and hydroureteronephrosis in infants and children. This was evaluated in 2 groups: furosemide clearance half-time (t 1/2) > 20 min (obstructed range) and t 1/2 = 10-20 min (indeterminate range). METHODS Two hundred children (155 boys, 45 girls; age range, 2 d to 16 y; median age, 26 wk) were studied over a 2-y period. One hundred thirty-five F+20 (diuretic given 20 min after radiopharmaceutical) and 65 F+0 (simultaneous administration of diuretic and radiopharmaceutical) studies were performed with intravenous administration of 99mTc-mercaptoacetyltriglycine (MAG3) and furosemide. At the end of the 20-min diuretic phase, a 5-min post-GAD image was obtained, and the percentage of residual activity was calculated by comparison with the last 5 min of the diuretic phase. All patients were monitored for 6-12 mo, and the final diagnoses were based on either surgical findings or conservative management with follow-up sonography or 99mTc-MAG3 studies. Results of the diuretic renography using quantitative GAD were then compared with the final diagnoses. RESULTS A renal unit was defined as a kidney and its ureter. In the 200 patients studied, 256 hydronephrotic renal units were analyzed: 10 units showed no function, 1 unit showed poor function, 131 units had t 1/2 < 10 min, 62 units had t 1/2 > 20 min, and 52 units had t 1/2 = 10-20 min. Of the 131 renal units with t 1/2 < 10 min, there was only 1 case of obstruction. Using GAD > 50% residual activity for the diagnosis of obstruction in 62 renal units with t 1/2 > 20 min, the sensitivity was 88.4%, the specificity was 73.7%, and the accuracy was 83.9%. Similarly, using GAD > 50% residual activity for the diagnosis of obstruction in 52 units with t 1/2 = 10-20 min, the sensitivity was 100%, the specificity was 79.5%, and the accuracy was 82.7%. CONCLUSION The quantitation of GAD > 50% residual activity in diuretic renography can help to differentiate between obstruction and nonobstruction in renal units with t 1/2 > 20 min and t 1/2 = 10-20 min. The quantitation of GAD when t 1/2 < 10 min is not useful because obstruction has already been excluded.
Characterization of MIMO Antennas Using Spherical Vector Waves

Spherical vector waves are used to analyze multiple-input multiple-output (MIMO) antennas. An expansion of the far-field pattern in spherical vector waves gives the correlation matrix and correlation loss of the MIMO antenna in uniform multipath channels. Numerical examples of a MIMO tetrahedron and a MIMO cube are presented
Possible evolutionary origins of human female sexual fluidity

I propose an evolutionary theory of human female sexual fluidity and argue that women may have been evolutionarily designed to be sexually fluid in order to allow them to have sex with their cowives in polygynous marriage and thus reduce conflict and tension inherent in such marriage. In addition to providing an extensive definition and operationalization of the concept of sexual fluidity and specifying its ultimate function for women, the proposed theory can potentially solve several theoretical and empirical puzzles in evolutionary psychology and sex research. Analyses of the National Longitudinal Study of Adolescent Health (Add Health) confirm the theory's predictions that: (i) women (but not men) who experience increased levels of sexual fluidity have a larger number of children (suggesting that female sexual fluidity, if heritable, may be evolutionarily selected); (ii) women (but not men) who experience marriage or parenthood early in adult life subsequently experience increased levels of sexual fluidity; and (iii) sexual fluidity is significantly positively correlated with known markers of unrestricted sexual orientation among women whereas it is significantly negatively correlated with such markers among men.
The Production of Social Meaning Via the Association of Variety and Style: A Case Study of French Vowel Lengthening in Belgian

Abstract This article questions the common usage of the concept of “linguistic variety” and the usual view of vernacular speech as the expression of a speaker’s identity. The term “variety” in linguistics has an ambiguous status: it is used to describe “linguistic representations” (social constructs) as well as actual linguistic practices. An alternative way of understanding the function of varieties in the sociolinguistic space is proposed: we explain how varieties relate to speech styles in a way that captures the social significance of linguistic variation. A case study about vowel lengthening in the French spoken in Belgium is then presented. Through both a quantitative and qualitative analysis, it is shown how marked regional variants are used to produce a particular social meaning, even among middle-class speakers.
Role of shelterin in cancer and aging

Mammalian telomeres are formed by tandem repeats of the TTAGGG sequence bound by a specialized six‐protein complex known as shelterin, which has fundamental roles in the regulation of telomere length and telomere capping. In the past, the study of mice genetically modified for telomerase components has been instrumental to demonstrate the role of telomere length in cancer and aging. Recent studies using genetically modified mice for shelterin proteins have highlighted an equally important role of telomere‐bound proteins in cancer and aging, even in the presence of proficient telomerase activity and normal telomere length. In this review, we will focus on recent findings, suggesting a role of shelterin components in cancer and aging.
Notch signaling is required for the maintenance of enteric neural crest progenitors

Notch signaling is involved in neurogenesis, including that of the peripheral nervous system as derived from neural crest cells (NCCs). However, it remains unclear which step is regulated by this signaling. To address this question, we took advantage of the Cre-loxP system to specifically eliminate the protein O-fucosyltransferase 1 (Pofut1) gene, which is a core component of Notch signaling, in NCCs. NCC-specific Pofut1-knockout mice died within 1 day of birth, accompanied by a defect of enteric nervous system (ENS) development. These embryos showed a reduction in enteric neural crest cells (ENCCs) resulting from premature neurogenesis. We found that Sox10 expression, which is normally maintained in ENCC progenitors, was decreased in Pofut1-null ENCCs. By contrast, the number of ENCCs that expressed Mash1, a potent repressor of Sox10, was increased in the Pofut1-null mouse. Given that Mash1 is suppressed via the Notch signaling pathway, we propose a model in which ENCCs have a cell-autonomous differentiating program for neurons as reflected in the expression of Mash1, and in which Notch signaling is required for the maintenance of ENS progenitors by attenuating this cell-autonomous program via the suppression of Mash1.
Ultrawideband Antenna Distortion Compensation

The radiation characteristics of ultrawideband (UWB) antennas vary with frequency, introducing directionally asymmetric bandwidth reduction and waveform dispersion. In this paper, we develop a simple technique to alleviate the distortion due to nonisotropically dispersive antennas, and use indoor channel measurements to verify its performance. The approach is based on multipath direction estimation and therefore involves antenna arrays. We show that antenna distortion can enhance sensor localization ambiguity and introduce errors in its estimate. Antenna compensation mitigates this effect, significantly improving the location estimation accuracy. We further demonstrate that antenna compensation helps reduce the small-scale fading artifacts that arise due to the antennas, thus reducing the channel spatial variability and delay spread. Our technique can also aid empirical channel characterization by providing antenna-independent propagation data.
Osmoregulatory modulation of thermal sweating in humans: reflex effects of drinking.

To gain better insight into the interaction between thermoregulation and osmoregulation, we examined the thermal sweating response to drinking in cell-dehydrated humans. Cell dehydration (CDH) was induced by infusion of a 3% NaCl solution, at 1.2 ml/kg, for 2 h; infusion of a 0.9% NaCl solution in a separate experiment served as a control (euhydrated condition, EH). After infusion, subjects were heated by immersion of the lower legs in 42 degrees C water at an ambient temperature of 28 degrees C for 90 min. Subjects drank 4.3 ml/kg of H2O (approximately 38 degrees C) at 60 min of heating. The 3% NaCl infusion increased plasma osmolality by 13.6 +/- 0.8 mosmol/kgH2O and plasma arginine vasopressin concentration ([AVP]) by 3.3 +/- 0.7 pg/ml. Neither variable was altered with 0.9% NaCl infusion. Before drinking, esophageal temperature (Tes) had increased by 0.91 +/- 0.08 degrees C in CDH and by 0.40 +/- 0.11 degrees C in EH. Local chest sweating rate (SRch) had increased by 0.67 +/- 0.08 and 0.63 +/- 0.07 mg.min-1.cm-2 in CDH and EH, respectively. Thus the change in SRch per unit rise in Tes was much lower in CDH than in EH. Drinking immediately increased SRch and reduced Tes in CDH, with a reduction in plasma [AVP] and thirst rating. Drinking did not change thermoregulatory and osmoregulatory responses in EH. These results suggest that the act of drinking itself eliminates, at least partially, an osmotic inhibitory input to the thermoregulatory center, as well as osmotic AVP secretion and thirst.
A Psychometric Investigation of the Wechsler Individual Achievement Test with a Sample of Saskatchewan Schoolchildren

The Wechsler Individual Achievement Test (WIAT, Psychological Corporation) was introduced in 1992. The purpose of this study was to examine the psyciiometric properfies and normative data of the WIAT with a sample of Canadian children. Ninety randomly selected Saskatchewan schoolchildren in grades 4, 5, and 6 were administered the WIAT in conjurcction with the Canadinn Achievement Test/2 (Canadian Test Centre, 1992). Teacher ratings of academic achievement and expert evaluations of the WIAT item content were obtained. Although there is support for the reliability and validity of the WIAT, prelimirzary data suggest the need fnr further study of Canadian children's perfornurnce on this test.
Alternative RNA Splicing of the NMDA Receptor NR1 mRNA in the Neurons of the Teleost Electrosensory System

The sequence for cDNA encoding the NMDA receptor subunit 1 (aptNR1) of the weakly electric fish Apteronotus leptorhynchushas been determined. The deduced amino acid sequence is ∼88% identical to other vertebrate NR1 proteins, with sequence homology extending to the alternatively spliced cassettes N1 and C1. The fish and mammalian N1 and C1 splice cassettes are identical at 20 of 21 and 30 of 37 amino acid positions, respectively. We did not detect a C2 splice cassette in aptNR1 mRNA, but we did find two novel C-terminal alternative splice cassettes labeled C1′ and C1". The relative levels of NR1 transcripts containing the N1 and C1 splice cassettes were determined by using RNase protection and in situ hybridization analysis. N1-containing mRNAs are more abundant in caudal brain regions, similar to the patterns reported for mammalian brain. In contrast, the relative levels of transcripts containing the C1 splice cassette are much lower in fish than in mammals, averaging only 9% for the whole brain. The levels of C1 splicing increased in more rostral brain regions. In situ hybridizations with N1- and C1-specific probes demonstrated that N1 cassette splicing occurs in most neurons but that C1 splicing is heterogeneous and is restricted to a subset of neuronal types in the electrosensory system.
The Relationship of School Belonging and Friends' Values to Academic Motivation Among Urban Adolescent Students

Abstract Students' subjective sense of school belonging recently has been identified as a potentially important influence on academic motivation, engagement, and participation, especially among students from groups at risk of school dropout. Students' friends also influence their academic motivation, sometimes negatively. In this study, the relationship among early adolescent students' sense of school belonging, perceptions of their friends' academic values, and academic motivation was investigated among 301 African-American, White/Anglo, and Hispanic students in two urban junior high schools. School belonging was significantly associated with several motivation-related measures—expectancy of success, valuing schoolwork, general school motivation, and self-reported effort. Students' beliefs about their friends' academic values were more weakly related to these outcomes. The correlations between school belonging and the motivation-related measures remained positive and statistically significant even after .
Skin cancer in Puerto Rico: a multiannual incidence comparative study.

BACKGROUND The incidence of skin cancer continues to increase worldwide. The purpose of this study was to determine the incidence of skin cancer in Puerto Rico in a selected year (2005) and to compare these findings with those previously reported for Puerto Rico in 1974 and 1981 and with other countries. METHODS The data was collected from the pathology reports corresponding to the period of January to December 2005 of 21 participating Pathology Laboratories throughout Puerto Rico. The rate and distribution of the main types of skin cancer was calculated based on sex, age, anatomic location and laterality. RESULTS The incidence of skin cancer in Puerto Rico for 2005 was 6,568 cases, which represent a rate of 167.9 per 100,000 inhabitants. The most common type of skin cancer was basal-cell carcinoma. Skin cancer was more common in males except for melanoma, which was more common in females. The incidence increases with age on all types of skin cancer. The head and neck area was the most frequent location, except for melanoma in women, which was more common on the legs. The incidence rate was 41.5/100,000 in 1974, 52.5/100,000 in 1981 and 167.9/100,000 in 2005, a 305% increase. CONCLUSIONS We found an increasing incidence of skin cancer in Puerto Rico when compared with previous reported data. This analysis provides a comprehensive evaluation of the epidemiology of skin cancer in Puerto Rico.
Scalability-based manycore partitioning

Multicore processors have been popular for years, and the industry is gradually shifting towards the era of manycore processors. Single-thread performance of microprocessors is not growing at a historical rate, but the existence of a number of active processes in the computer system and the continuing development of multi-threaded applications benefit from the growing core counts to sustain system throughput. This trend brings us a situation where a number of parallel applications simultaneously being executed on a single system. Since multi-threaded applications try to maximize its throughput by utilizing the whole system, each of them usually create equal or larger number of threads compared to underlying logical core counts. This introduces much greater number of threads to be co-scheduled in the entire system. However, each program has different characteristics (or scalability) and contends for shared resources, which are the CPU cores and memory hierarchies, with each other. Therefore, it is clear that OS thread scheduling will play a major role in achieving high system performance under such conditions. We develop a sophisticated scheduler that (1) dynamically predicts the scalability of programs via the use of hardware performance monitoring units, (2) decides the optimal number of cores to be allocated for each program, and (3) allocates the cores to programs while maximizing the system utilization to achieve fair and maximum performance. The evaluation results on a 48-core AMD Opteron system show improvements over the Linux scheduler for a variety of multiprogramming workloads.
Measurement of Personality Change in an Alcoholic Treatment Program: Further Validation of the Personal Orientation Dimensions

This study was designed to examine the validity of the Personal Orientation Dimensions (POD) for measuring changes following an inpatient alcoholic treatment program and to describe these changes in terms of concepts of the actualizing person. Differences between pretest and posttest raw scores were significant for 9 of 13 POD scales. Eight of the changes were in the direction of greater actualizing and one in the direction of greater social conformity. It was concluded that the POD was sensitive to changes resulting from the present alcoholic treatment program and that these changes were generally in the direction of greater actualizing.
Formation of a Quasar Host Galaxy through a Wet Merger 1.4 Billion Years after the Big Bang

We present high-resolution Very Large Array imaging of the molecular gas in the host galaxy of the high-redshift quasar BRI 1335–0417 (z = 4.41). Our CO(J = 2→ 1) observations have a linear resolution of 0.15′ ′ (1.0 kpc) and resolve the molecular gas emission both spatially and in velocity. The molecular gas in BRI 1335–0417 is extended on scales of 5 kpc, and shows a complex structure. At least three distinct components encompassing about two-thirds of the total molecular mass of 9.2 × 1010 M☉ are identified in velocity space, which are embedded in a structure that harbors about one-third of the total molecular mass in the system. The brightest CO(J = 2→ 1) line emission region has a peak brightness temperature of 61 ± 9 K within 1 kpc diameter, which is comparable to the kinetic gas temperature as predicted from the CO line excitation. This is also comparable to the gas temperatures found in the central regions of nearby ultraluminous infrared galaxies, which are however much more compact than 1 kpc. The spatial and velocity structure of the molecular reservoir in BRI 1335–0417 is inconsistent with a simple gravitationally bound disk, but resembles a merging system. Our observations are consistent with a major, gas-rich (“wet”) merger that both feeds an accreting supermassive black hole (causing the bright quasar activity), and fuels a massive starburst that builds up the stellar bulge in this galaxy. Our study of this z > 4 quasar host galaxy may thus be the most direct observational evidence that wet mergers at high redshift are related to AGN activity.
Spatial Distribution of the Pathways of Cholesterol Homeostasis in Human Retina

Background The retina is a light-sensitive tissue lining the inner surface of the eye and one of the few human organs whose cholesterol maintenance is still poorly understood. Challenges in studies of the retina include its complex multicellular and multilayered structure; unique cell types and functions; and specific physico-chemical environment. Methodology/Principal Findings We isolated specimens of the neural retina (NR) and underlying retinal pigment epithelium (RPE)/choroid from six deceased human donors and evaluated them for expression of genes and proteins representing the major pathways of cholesterol input, output and regulation. Eighty-four genes were studied by PCR array, 16 genes were assessed by quantitative real time PCR, and 13 proteins were characterized by immunohistochemistry. Cholesterol distribution among different retinal layers was analyzed as well by histochemical staining with filipin. Our major findings pertain to two adjacent retinal layers: the photoreceptor outer segments of NR and the RPE. We demonstrate that in the photoreceptor outer segments, cholesterol biosynthesis, catabolism and regulation via LXR and SREBP are weak or absent and cholesterol content is the lowest of all retinal layers. Cholesterol maintenance in the RPE is different, yet the gene expression also does not appear to be regulated by the SREBPs and varies significantly among different individuals. Conclusions/Significance This comprehensive investigation provides important insights into the relationship and spatial distribution of different pathways of cholesterol input, output and regulation in the NR-RPE region. The data obtained are important for deciphering the putative link between cholesterol and age-related macular degeneration, a major cause of irreversible vision loss in the elderly.
Membrane Potential-Dependent Modulation of Recurrent Inhibition in Rat Neocortex

Dynamic balance of excitation and inhibition is crucial for network stability and cortical processing, but it is unclear how this balance is achieved at different membrane potentials (V m) of cortical neurons, as found during persistent activity or slow V m oscillation. Here we report that a V m-dependent modulation of recurrent inhibition between pyramidal cells (PCs) contributes to the excitation-inhibition balance. Whole-cell recording from paired layer-5 PCs in rat somatosensory cortical slices revealed that both the slow and the fast disynaptic IPSPs, presumably mediated by low-threshold spiking and fast spiking interneurons, respectively, were modulated by changes in presynaptic V m. Somatic depolarization (>5 mV) of the presynaptic PC substantially increased the amplitude and shortened the onset latency of the slow disynaptic IPSPs in neighboring PCs, leading to a narrowed time window for EPSP integration. A similar increase in the amplitude of the fast disynaptic IPSPs in response to presynaptic depolarization was also observed. Further paired recording from PCs and interneurons revealed that PC depolarization increases EPSP amplitude and thus elevates interneuronal firing and inhibition of neighboring PCs, a reflection of the analog mode of excitatory synaptic transmission between PCs and interneurons. Together, these results revealed an immediate V m-dependent modulation of cortical inhibition, a key strategy through which the cortex dynamically maintains the balance of excitation and inhibition at different states of cortical activity.