Miracle-dz/UniFAR-FTUs huggingface dataset:
The Validity of Police Gang Intelligence Lists: Examining Differences in Delinquency Between Documented Gang Members and Nondocumented Delinquent Youth

Over the past 15 years, the United States has seen a dramatic increase in the number of specialized gang units established by police departments across the country. The majority of these units were established for the purpose of gathering intelligence on gangs, gang members, and gang-related activity. The present study seeks to advance the understanding of the usefulness of gang intelligence systems. In particular, the authors focus on how successful the police are at identifying and documenting youth whom they believe pose a substantial threat to the community. Using data obtained from the Mesa, Arizona, police department's gang unit and the Maricopa County Juvenile Probation Department, the authors found that gang lists may be more helpful to the police than first believed. Policy implications are presented along with recommendations for future research.
Scheduling Commercial Videotapes in Broadcast Television

This paper, motivated by the experiences of a major U.S.-based broadcast television network, presents algorithms and heuristics to schedule commercial videotapes. Major advertisers purchase several slots to air commercials during a given time period on a broadcast network. We study the problem of scheduling advertiser's commercials in the slots it purchased when the same commercial is to be aired multiple times. Under such a situation, the advertisers typically want the airings of a commercial to be as evenly spaced as possible. Thus, our objective is to schedule a set of commercials in a set of available slots such that multiple airings of the same commercial are as evenly spaced as possible. A natural formulation of this problem is a mixed-integer program that can be solved using third-party solvers. We also develop a branch-and-bound algorithm based on a problem-specific bounding scheme. Both approaches fail to solve larger problem instances within a reasonable time frame. We present an alternative mixed-integer program that lends itself to an efficient solution. For solving even larger problems, we present multiple heuristics.
Researching education and the environment: retrospect and prospect

Previously published as a special issue of Environmental Education Research, this collection includes some of the most influential and important articles contributed to the field over the last decade. Drawing out the best articles from volumes one to ten, the editors highlight six major themes: * EE and ESD: tension or transition? * locating the environmental in environmental education research * doing environmental education research * environmental learning as process and outcome * environmental education for . * developing environmental education research. For each theme, two papers published by the journal in the first ten years are re-printed and two researchers review the issues they raise, giving readers a broad and future-facing overview of the development of the field today.
DGA comparison between ester and mineral oils

This paper reports on a comparative study between mineral and ester oils basing on DGA (Dissolved Gas Analysis). Electrical (breakdown of low energy) and thermal (stray gassing) faults are realized at laboratory scale and gas formation as well as diagnosis methods are compared. Two extraction methods described in IEC 60567 were used: total vacuum degassing and stripping method. Three different diagnosis methods were used: IEC 60599 gas ratios, Duval's triangle and key gases. It appears that for electrical faults and especially for low energy discharges, the same gases (Hydrogen and Acetylene), in relatively same ratios, are created. It is shown that classic Duval's triangle is well applicable for this type of fault confirming thus the results reported in literature. For thermal faults and especially for stray gassing issue (low thermal faults), Ethane (associated with Hydrogen) constitutes the key gas of natural esters and the new Duval's triangle can be applied for mineral oil whereas some arrangements need to be introduced for ester oils.
Cortical Mapping of Gait in Humans: A Near-Infrared Spectroscopic Topography Study

While we have a fair understanding of how and where forelimb-hand manipulative movements are controlled by the neocortex, due to functional imaging studies, we know little about the control of bipedal movements such as walking because of technical difficulties. We succeeded in visualizing cortical activation patterns of human gait by measuring relative changes in local hemoglobin oxygenation using a recently developed near-infrared spectroscopic (NIRS) topography technique. Walking activities were bilaterally associated with increased levels of oxygenated and total hemoglobin in the medial primary sensorimotor cortices and the supplementary motor areas. Alternating foot movements activated similar but less broad regions. Gait imagery increased activities caudally located in the supplementary motor areas. These findings provide new insight into cortical control of human locomotion. NIRS topography might be also useful for evaluating cerebral activation patterns during pathological gait and rehabilitative intervention.
Gallbladder Cancer in the 21st Century

Gallbladder cancer (GBC) is an uncommon disease in the majority of the world despite being the most common and aggressive malignancy of the biliary tree. Early diagnosis is essential for improved prognosis; however, indolent and nonspecific clinical presentations with a paucity of pathognomonic/predictive radiological features often preclude accurate identification of GBC at an early stage. As such, GBC remains a highly lethal disease, with only 10% of all patients presenting at a stage amenable to surgical resection. Among this select population, continued improvements in survival during the 21st century are attributable to aggressive radical surgery with improved surgical techniques. This paper reviews the current available literature of the 21st century on PubMed and Medline to provide a detailed summary of the epidemiology and risk factors, pathogenesis, clinical presentation, radiology, pathology, management, and prognosis of GBC.
Energy expenditure in adults living in developing compared with industrialized countries: a meta-analysis of doubly labeled water studies.

BACKGROUND There is an assumption that people in developing countries have a higher total energy expenditure (TEE) and physical activity level (PAL) than do people in developed nations, but few objective data for this assertion exist. OBJECTIVE We conducted a meta-analysis of TEE and PAL by using data from countries that have a low or middle human development index (HDI) compared with those with a high HDI to better understand how energy-expenditure variables are associated with development status and population differences in body size. DESIGN We performed a literature search for studies in which energy expenditure was measured by using doubly labeled water. Mean data on age, weight, body mass index (BMI; in kg/m(2)), TEE, and PAL were extracted, and HDI status was assessed. Pooled estimates of the mean effect by sex were obtained, and the extent to which age, weight, HDI status, and year of publication explained heterogeneity was assessed. RESULTS A total of 98 studies (14 studies from low- or middle-HDI countries) that represented 183 cohorts and 4972 individuals were included. Mean (±SE) BMI was lower in countries with a low or middle HDI than in those with a high HDI for both men and women (22.7 ± 1.0 compared with 26.0 ± 0.7, respectively, in men and 24.3 ± 0.7 compared with 26.6 ± 0.4, respectively, in women). In meta-regression models, there was an inverse association of age (P < 0.001) and a positive association of weight (P < 0.001) with TEE for both sexes; there was an association of age only in men with PAL (P < 0.001). There was no association of HDI status with either TEE or PAL. CONCLUSION TEE adjusted for weight and age or PAL did not differ significantly between developing and industrialized countries, which calls into question the role of energy expenditure in the cause of obesity at the population level.
Hey! It was just a joke! Understanding propositions and propositional attitudes by normally developing children and children with autism.

Two- and three-year-old children were asked why a speaker named objects falsely. Most produced explanations in terms of the speaker's intention to joke. This implies a sensitivity to two distinct levels in language: the proposition itself and the propositional attitude. Children with learning difficulties showed a similar competence. In contrast, most children with autism failed to explain such false statements in these terms, instead merely describing them as "wrong. " This was not simply due to a metalinguistic deficit, as they correctly answered questions about what a speaker had said the object was. These results suggest the normally developing toddler has a remarkable facility in processing propositional attitudes, while children with autism do not; and that such an ability is broadly independent of general intelligence.
Characterization of the 1p/19q Chromosomal Loss in Oligodendrogliomas Using Comparative Genomic Hybridization Arrays (CGHa)

Abstract Loss of genetic material from the short arm of chromosome 1 and the long arm of chromosome 19 in anaplastic oligodendrogliomas has been shown to predict responsiveness to chemotherapy. Currently, the most common approach used to detect this loss of 1p/19q material employs microsatellite/FISH analysis using markers along the length of these chromosome arms. This analysis is highly focused and carried out on a locus-by-locus basis and gives no indication of the extent of other genetic changes occurring in the tumor cells, which may be important in future studies to explore genetic heterogeneity in the response to treatment. We have investigated the use of comparative genomic hybridization arrays (CGHa) of bacterial artificial chromosomes (BACs) in the identification of tumor samples that carry loss of the 1p/19q chromosome arms. These BAC arrays carry approximately 6,000 BAC clones and provide an average inter-BAC resolution of 500 Kb. Using this approach we have clearly shown that 1p/19q loss in these cases, when compared with microsatellite-mediated detection of loss of heterozygosity, is due to physical hemizygous deletion of the whole chromosome arms in all cases. Furthermore, CGHa allows the simultaneous definition of the other genetic changes that are occurring in the tumors. From our survey of 14 tumors consisting of low-grade oligodendrogliomas (n = 6), anaplastic oligodendrogliomas (n = 5), or mixed oligoastrocytoma (n = 3), we were able to demonstrate the presence of additional genetic markers that were characteristic of the various grades of tumors as well as novel changes that had occurred. Thus, CGHa provides a robust, high throughput, genome-wide analysis of genetic changes of oligodendroglial tumors that can be used not only to predict chemo-responsiveness but also place these genetic changes in the context of other abnormalities in the same experiment without the need for extensive chromosome or LOH analysis.
Angiotensin-(1–7) Attenuates the Development of Heart Failure After Myocardial Infarction in Rats

Background—The renin-angiotensin system (RAS) is a key player in the progression of heart failure. Angiotensin-(1–7) is thought to modulate the activity of the RAS. Furthermore, this peptide may play a part in the beneficial effects of angiotensin-converting enzyme inhibitors in cardiovascular disease. We assessed the effects of angiotensin-(1–7) on the progression of heart failure. Methods and Results—Male Sprague-Dawley rats underwent either coronary ligation or sham surgery. Two weeks after induction of myocardial infarction, intravenous infusion of angiotensin-(1–7) (24 &mgr;g/kg per hour) or saline was started by minipump. After 8 weeks of treatment, hemodynamic parameters were measured, endothelial function was assessed in isolated aortic rings, and plasma angiotensin-(1–7) levels were determined. Myocardial infarction resulted in a significant deterioration of left ventricular systolic and diastolic pressure, dP/dt, and coronary flow. Raising plasma levels 40-fold, angiotensin-(1–7) infusion attenuated this impairment to a nonsignificant level, markedly illustrated by a 40% reduction in left ventricular end-diastolic pressure. Furthermore, angiotensin-(1–7) completely preserved aortic endothelial function, whereas endothelium-dependent relaxation in aortas of saline-treated infarcted rats was significantly decreased. Conclusions—Angiotensin-(1–7) preserved cardiac function, coronary perfusion, and aortic endothelial function in a rat model for heart failure.
Joint Discussion Paper Series in Economics by the Universities of Aachen ∙ Gießen ∙

Cryptocurrencies such as Bitcoin might revolutionize the economy through enabling peer-to-peer based transactions by abolishing the need for a trusted intermediary. As for now, Bitcoin remains to be the best recognized cryptocurrency, in particular in terms of market capitalization. However, as this paper shows, there are plenty of alternatives. This paper outlines the historical roots which have led to the creation of privately emitted, cryptography based digital currencies. Additionally, this paper discusses future possible hurdles of the development of cryptocurrencies and outlines features which might influence the success of a cryptocurrency. Insights into the beginning of cryptocurrency development are gained by analysis of the publicly available DOACC dataset. The paper does so by providing an overview of the techniques and mechanisms used by cryptocurrencies. It shows that newly created cryptocurrencies tend to be very similar in some properties in the early stages but new features and more diversity developed in more recent years. Additionally, newly created cryptocurrencies tend more and more to create a fixed number of coins before the initial announcement in order to sell these in Initial Coin Offerings. Even when the amount of premining increases over years, it remains at lower levels on the aggregate.
Diagnóstico diferencial de envejecimiento patológico. Desempeños en el Addenbrooke’s Cognitive Examination (ACE)

The objective of this research is to determine the percentage of adults that show a certain tendency to suffer from frontotemporal dementia (FTD) or Alzheimer’s disease (AD) from the scores obtained in the VLOM coefficient, and if these values may vary according to gender, level of education and history of illness. The study was carried out with 649 adults from Rio Cuarto, Cordoba, Argentina with the application of the ACE (Addenbrooke’s Cognitive Examination) instrument of Mathuranath et al., (2000) in an adapted version. A chi-squared analysis was made, together with average comparision and Anova, to establish whether there are differences in scores in the instrument by groups. The results show that there are no significant differences by gender, but certain tendencies stand out according to age, level of education and history of illness.
Aetiology of the relationship between callous-unemotional traits and conduct problems in childhood.

BACKGROUND A callous and unemotional disposition is an indicator of early-onset antisocial behaviour. AIMS To investigate the extent to which genetic influences contribute to the overlap between callous-unemotional traits and conduct problems in a large population sample of 7-year-old twins. METHOD Teachers provided ratings of callous-unemotional traits and conduct problems for 3434 twin pairs from the Twins Early Development Study. Model-fitting analyses were performed across the continuum of scores and at the extremes. RESULTS The phenotypic relationship was primarily genetically mediated, both across the continuum and at the extremes and was substantial. CONCLUSIONS At 7 years of age, genetic influences on callous-unemotional traits overlap substantially with genetic influences on conduct problems. This combination should guide selection criteria in future molecular genetic studies.
Neighbor-aware dynamic backoff algorithm for wireless multihop ad hoc networks

In this paper, we propose a neighbor-aware dynamic backoff scheme and evaluate the performance of the proposed scheme for ad hoc networks. The backoff scheme that we devised grants node access to the channel, according to the competing number of nodes for a transmitted frame. We use both an analytical model and simulation experiments to evaluate the dynamic performance of our backoff mechanism in an ad hoc network.
The sunflower downy mildew pathogen Plasmopara halstedii.

UNLABELLED Downy mildew of sunflower is caused by Plasmopara halstedii (Farlow) Berlese & de Toni. Plasmopara halstedii is an obligate biotrophic oomycete pathogen that attacks annual Helianthus species and cultivated sunflower, Helianthus annuus. Depending on the sunflower developmental stage at which infection occurs, the characteristic symptoms range from young seedling death, plant dwarfing, leaf bleaching and sporulation to the production of infertile flowers. Downy mildew attacks can have a great economic impact on sunflower crops, and several Pl resistance genes are present in cultivars to protect them against the disease. Nevertheless, some of these resistances have been overcome by the occurrence of novel isolates of the pathogen showing increased virulence. A better characterization of P. halstedii infection and dissemination mechanisms, and the identification of the molecular basis of the interaction with sunflower, is a prerequisite to efficiently fight this pathogen. This review summarizes what is currently known about P. halstedii, provides new insights into its infection cycle on resistant and susceptible sunflower lines using scanning electron and light microscopy imaging, and sheds light on the pathogenicity factors of P. halstedii obtained from recent molecular data. TAXONOMY Kingdom Stramenopila; Phylum Oomycota; Class Oomycetes; Order Peronosporales; Family Peronosporaceae; Genus Plasmopara; Species Plasmopara halstedii. DISEASE SYMPTOMS Sunflower seedling damping off, dwarfing of the plant, bleaching of leaves, starting from veins, and visible white sporulation, initially on the lower side of cotyledons and leaves. Plasmopara halstedii infection may severely impact sunflower seed yield. INFECTION PROCESS In spring, germination of overwintered sexual oospores leads to sunflower root infection. Intercellular hyphae are responsible for systemic plant colonization and the induction of disease symptoms. Under humid and fresh conditions, dissemination structures are produced by the pathogen on all plant organs to release asexual zoosporangia. These zoosporangia play an important role in pathogen dissemination, as they release motile zoospores that are responsible for leaf infections on neighbouring plants. DISEASE CONTROL Disease control is obtained by both chemical seed treatment (mefenoxam) and the deployment of dominant major resistance genes, denoted Pl. However, the pathogen has developed fungicide resistance and has overcome some plant resistance genes. Research for more sustainable strategies based on the identification of the molecular basis of the interaction are in progress. USEFUL WEBSITES http://www.heliagene. org/HP, http://lipm-helianthus.toulouse. inra.fr/dokuwiki/doku.php? id=start, https://www.heliagene. org/PlasmoparaSpecies (soon available).
Evolution of Heterogeneity (I2) Estimates and Their 95% Confidence Intervals in Large Meta-Analyses

Background Assessment of heterogeneity is essential in systematic reviews and meta-analyses of clinical trials. The most commonly used heterogeneity measure, I2, provides an estimate of the proportion of variability in a meta-analysis that is explained by differences between the included trials rather than by sampling error. Recent studies have raised concerns about the reliability of I2 estimates, due to their dependence on the precision of included trials and time-dependent biases. Authors have also advocated use of 95% confidence intervals (CIs) to express the uncertainty associated with I2 estimates. However, no previous studies have explored how many trials and events are required to ensure stable and reliable I2 estimates, or how 95% CIs perform as evidence accumulates. Methodology/Principal Findings To assess the stability and reliability of I2 estimates and their 95% CIs, in relation to the cumulative number of trials and events in meta-analysis, we looked at 16 large Cochrane meta-analyses - each including a sufficient number of trials and events to reliably estimate I2 - and monitored the I2 estimates and their 95% CIs for each year of publication. In 10 of the 16 meta-analyses, the I2 estimates fluctuated more than 40% over time. The median number of events and trials required before the cumulative I2 estimates stayed within +/−20% of the final I2 estimate was 467 and 11. No major fluctuations were observed after 500 events and 14 trials. The 95% confidence intervals provided good coverage over time. Conclusions/Significance I2 estimates need to be interpreted with caution when the meta-analysis only includes a limited number of events or trials. Confidence intervals for I2 estimates provide good coverage as evidence accumulates, and are thus valuable for reflecting the uncertainty associated with estimating I2.
Altered Starch Turnover in the Maternal Plant Has Major Effects on Arabidopsis Fruit Growth and Seed Composition1[W][OA]

Mature seeds of both the high-starch starch-excess1 (sex1) mutant and the almost starchless phosphoglucomutase1 mutant of Arabidopsis (Arabidopsis thaliana) have 30% to 40% less lipid than seeds of wild-type plants. We show that this is a maternal effect and is not attributable to the defects in starch metabolism in the embryo itself. Low lipid contents and consequent slow postgerminative growth are seen only in mutant embryos that develop on maternal plants with mutant phenotypes. Mutant embryos that develop on plants with wild-type starch metabolism have wild-type lipid contents and postgerminative growth. The maternal effect on seed lipid content is attributable to carbohydrate starvation in the mutant fruit at night. Fruits on sex1 plants grow more slowly than those on wild-type plants, particularly at night, and have low sugars and elevated expression of starvation genes at night. Transcript levels of the transcription factor WRINKLED1, implicated in lipid synthesis, are reduced at night in sex1 but not in wild-type seeds, and so are transcript levels of key enzymes of glycolysis and fatty acid synthesis. sex1 embryos develop more slowly than wild-type embryos. We conclude that the reduced capacity of mutant plants to convert starch to sugars in leaves at night results in low nighttime carbohydrate availability in the developing fruit. This in turn reduces the rate of development and expression of genes encoding enzymes of storage product accumulation in the embryo. Thus, the supply of carbohydrate from the maternal plant to the developing fruit at night can have an important influence on oilseed composition and on postgerminative growth.
Application of the random field theory in PET imaging - injection dose optimization

This work presents new application of the random field theory in medical imaging. Results from both integral geometry and random field theory can be used to detect locations with significantly increased radiotracer uptake in images from positron emission tomography (PET). The assumptions needed to use these results are verified on a set of real and simulated phantom images. The proposed method of detecting activation (locations with increased radiotracer concentration) is used to quantify the quality of simulated PET images. Dependence of the quality on the injection dose (amount of applied radiotracer) and patient’s body parameters is estimated. It is used to derive curves of constant quality determining the injection dose needed to achieve desired quality of the resulting images. The curves are compared with the formula currently used in medical practice.